Amino acid dipepetide frequency for Chimeric virus 14

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.322AlaAla: 3.322 ± 0.84
0.0AlaCys: 0.0 ± 0.0
7.752AlaAsp: 7.752 ± 0.862
4.43AlaGlu: 4.43 ± 1.669
3.322AlaPhe: 3.322 ± 2.455
3.322AlaGly: 3.322 ± 2.455
4.43AlaHis: 4.43 ± 1.669
3.322AlaIle: 3.322 ± 2.455
4.43AlaLys: 4.43 ± 1.669
7.752AlaLeu: 7.752 ± 0.785
3.322AlaMet: 3.322 ± 0.807
5.537AlaAsn: 5.537 ± 0.851
11.074AlaPro: 11.074 ± 0.055
1.107AlaGln: 1.107 ± 0.818
2.215AlaArg: 2.215 ± 0.011
5.537AlaSer: 5.537 ± 2.444
6.645AlaThr: 6.645 ± 1.614
1.107AlaVal: 1.107 ± 0.818
0.0AlaTrp: 0.0 ± 0.0
1.107AlaTyr: 1.107 ± 0.829
0.0AlaXaa: 0.0 ± 0.0
Cys
1.107CysAla: 1.107 ± 0.818
0.0CysCys: 0.0 ± 0.0
1.107CysAsp: 1.107 ± 0.829
1.107CysGlu: 1.107 ± 0.829
0.0CysPhe: 0.0 ± 0.0
1.107CysGly: 1.107 ± 0.829
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
2.215CysLys: 2.215 ± 0.011
1.107CysLeu: 1.107 ± 0.829
1.107CysMet: 1.107 ± 0.818
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.107CysSer: 1.107 ± 0.829
0.0CysThr: 0.0 ± 0.0
1.107CysVal: 1.107 ± 0.829
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.215AspAla: 2.215 ± 0.011
0.0AspCys: 0.0 ± 0.0
2.215AspAsp: 2.215 ± 1.658
6.645AspGlu: 6.645 ± 4.975
1.107AspPhe: 1.107 ± 0.818
3.322AspGly: 3.322 ± 0.84
0.0AspHis: 0.0 ± 0.0
5.537AspIle: 5.537 ± 0.851
6.645AspLys: 6.645 ± 3.327
6.645AspLeu: 6.645 ± 3.327
1.107AspMet: 1.107 ± 0.818
3.322AspAsn: 3.322 ± 2.487
2.215AspPro: 2.215 ± 0.011
2.215AspGln: 2.215 ± 0.011
3.322AspArg: 3.322 ± 2.487
3.322AspSer: 3.322 ± 0.84
2.215AspThr: 2.215 ± 0.011
3.322AspVal: 3.322 ± 0.84
2.215AspTrp: 2.215 ± 1.658
6.645AspTyr: 6.645 ± 0.033
0.0AspXaa: 0.0 ± 0.0
Glu
1.107GluAla: 1.107 ± 0.829
1.107GluCys: 1.107 ± 0.818
5.537GluAsp: 5.537 ± 4.146
5.537GluGlu: 5.537 ± 4.146
3.322GluPhe: 3.322 ± 0.807
0.0GluGly: 0.0 ± 0.0
2.215GluHis: 2.215 ± 1.658
2.215GluIle: 2.215 ± 1.658
3.322GluLys: 3.322 ± 2.487
6.645GluLeu: 6.645 ± 1.68
1.107GluMet: 1.107 ± 0.829
3.322GluAsn: 3.322 ± 0.807
3.322GluPro: 3.322 ± 0.84
1.107GluGln: 1.107 ± 0.818
1.107GluArg: 1.107 ± 0.829
3.322GluSer: 3.322 ± 0.84
1.107GluThr: 1.107 ± 0.829
1.107GluVal: 1.107 ± 0.818
1.107GluTrp: 1.107 ± 0.829
2.215GluTyr: 2.215 ± 0.011
0.0GluXaa: 0.0 ± 0.0
Phe
4.43PheAla: 4.43 ± 1.669
0.0PheCys: 0.0 ± 0.0
3.322PheAsp: 3.322 ± 2.487
1.107PheGlu: 1.107 ± 0.818
1.107PhePhe: 1.107 ± 0.818
3.322PheGly: 3.322 ± 2.455
0.0PheHis: 0.0 ± 0.0
3.322PheIle: 3.322 ± 0.807
2.215PheLys: 2.215 ± 0.011
0.0PheLeu: 0.0 ± 0.0
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
3.322PhePro: 3.322 ± 2.455
3.322PheGln: 3.322 ± 0.807
1.107PheArg: 1.107 ± 0.818
3.322PheSer: 3.322 ± 0.84
6.645PheThr: 6.645 ± 1.614
2.215PheVal: 2.215 ± 1.658
0.0PheTrp: 0.0 ± 0.0
1.107PheTyr: 1.107 ± 0.818
0.0PheXaa: 0.0 ± 0.0
Gly
8.859GlyAla: 8.859 ± 4.898
0.0GlyCys: 0.0 ± 0.0
4.43GlyAsp: 4.43 ± 1.625
3.322GlyGlu: 3.322 ± 0.807
3.322GlyPhe: 3.322 ± 2.455
5.537GlyGly: 5.537 ± 0.796
2.215GlyHis: 2.215 ± 0.011
3.322GlyIle: 3.322 ± 0.807
9.967GlyLys: 9.967 ± 0.873
6.645GlyLeu: 6.645 ± 1.614
3.322GlyMet: 3.322 ± 2.455
3.322GlyAsn: 3.322 ± 0.807
1.107GlyPro: 1.107 ± 0.818
0.0GlyGln: 0.0 ± 0.0
1.107GlyArg: 1.107 ± 0.818
7.752GlySer: 7.752 ± 2.433
3.322GlyThr: 3.322 ± 2.455
5.537GlyVal: 5.537 ± 2.444
0.0GlyTrp: 0.0 ± 0.0
1.107GlyTyr: 1.107 ± 0.818
0.0GlyXaa: 0.0 ± 0.0
His
2.215HisAla: 2.215 ± 1.658
0.0HisCys: 0.0 ± 0.0
2.215HisAsp: 2.215 ± 1.658
1.107HisGlu: 1.107 ± 0.829
1.107HisPhe: 1.107 ± 0.829
2.215HisGly: 2.215 ± 1.636
0.0HisHis: 0.0 ± 0.0
1.107HisIle: 1.107 ± 0.829
1.107HisLys: 1.107 ± 0.829
3.322HisLeu: 3.322 ± 2.487
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.107HisPro: 1.107 ± 0.829
0.0HisGln: 0.0 ± 0.0
3.322HisArg: 3.322 ± 0.84
0.0HisSer: 0.0 ± 0.0
1.107HisThr: 1.107 ± 0.829
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
1.107HisTyr: 1.107 ± 0.818
0.0HisXaa: 0.0 ± 0.0
Ile
8.859IleAla: 8.859 ± 1.691
0.0IleCys: 0.0 ± 0.0
2.215IleAsp: 2.215 ± 1.658
3.322IleGlu: 3.322 ± 2.455
2.215IlePhe: 2.215 ± 1.636
4.43IleGly: 4.43 ± 3.273
2.215IleHis: 2.215 ± 0.011
4.43IleIle: 4.43 ± 0.022
4.43IleLys: 4.43 ± 3.317
3.322IleLeu: 3.322 ± 0.84
2.215IleMet: 2.215 ± 0.011
3.322IleAsn: 3.322 ± 0.807
2.215IlePro: 2.215 ± 0.011
1.107IleGln: 1.107 ± 0.829
0.0IleArg: 0.0 ± 0.0
7.752IleSer: 7.752 ± 2.433
2.215IleThr: 2.215 ± 1.636
4.43IleVal: 4.43 ± 1.669
1.107IleTrp: 1.107 ± 0.829
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
8.859LysAla: 8.859 ± 0.044
1.107LysCys: 1.107 ± 0.829
1.107LysAsp: 1.107 ± 0.818
4.43LysGlu: 4.43 ± 3.317
2.215LysPhe: 2.215 ± 1.658
4.43LysGly: 4.43 ± 1.669
2.215LysHis: 2.215 ± 1.658
7.752LysIle: 7.752 ± 2.509
3.322LysLys: 3.322 ± 0.84
4.43LysLeu: 4.43 ± 1.669
2.215LysMet: 2.215 ± 1.658
2.215LysAsn: 2.215 ± 0.011
6.645LysPro: 6.645 ± 1.68
2.215LysGln: 2.215 ± 1.636
2.215LysArg: 2.215 ± 0.011
5.537LysSer: 5.537 ± 0.851
3.322LysThr: 3.322 ± 2.487
2.215LysVal: 2.215 ± 1.658
1.107LysTrp: 1.107 ± 0.829
2.215LysTyr: 2.215 ± 1.658
0.0LysXaa: 0.0 ± 0.0
Leu
8.859LeuAla: 8.859 ± 0.044
1.107LeuCys: 1.107 ± 0.829
7.752LeuAsp: 7.752 ± 4.157
1.107LeuGlu: 1.107 ± 0.829
1.107LeuPhe: 1.107 ± 0.829
8.859LeuGly: 8.859 ± 3.251
2.215LeuHis: 2.215 ± 0.011
4.43LeuIle: 4.43 ± 1.669
3.322LeuLys: 3.322 ± 2.487
3.322LeuLeu: 3.322 ± 2.487
0.0LeuMet: 0.0 ± 0.0
2.215LeuAsn: 2.215 ± 1.658
3.322LeuPro: 3.322 ± 0.84
0.0LeuGln: 0.0 ± 0.0
4.43LeuArg: 4.43 ± 1.669
2.215LeuSer: 2.215 ± 1.658
7.752LeuThr: 7.752 ± 0.785
1.107LeuVal: 1.107 ± 0.818
2.215LeuTrp: 2.215 ± 0.011
3.322LeuTyr: 3.322 ± 0.807
0.0LeuXaa: 0.0 ± 0.0
Met
1.107MetAla: 1.107 ± 0.818
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
1.107MetGlu: 1.107 ± 0.818
0.0MetPhe: 0.0 ± 0.0
1.107MetGly: 1.107 ± 0.818
0.0MetHis: 0.0 ± 0.0
1.107MetIle: 1.107 ± 0.818
1.107MetLys: 1.107 ± 0.829
4.43MetLeu: 4.43 ± 1.669
1.107MetMet: 1.107 ± 0.818
0.0MetAsn: 0.0 ± 0.0
1.107MetPro: 1.107 ± 0.818
1.107MetGln: 1.107 ± 0.818
2.215MetArg: 2.215 ± 0.011
3.322MetSer: 3.322 ± 0.807
0.0MetThr: 0.0 ± 0.0
3.322MetVal: 3.322 ± 0.84
1.107MetTrp: 1.107 ± 0.829
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.215AsnAla: 2.215 ± 1.658
1.107AsnCys: 1.107 ± 0.829
1.107AsnAsp: 1.107 ± 0.829
1.107AsnGlu: 1.107 ± 0.829
4.43AsnPhe: 4.43 ± 0.022
6.645AsnGly: 6.645 ± 0.033
1.107AsnHis: 1.107 ± 0.829
3.322AsnIle: 3.322 ± 0.807
2.215AsnLys: 2.215 ± 1.658
2.215AsnLeu: 2.215 ± 0.011
0.0AsnMet: 0.0 ± 0.0
2.215AsnAsn: 2.215 ± 0.011
3.322AsnPro: 3.322 ± 0.84
1.107AsnGln: 1.107 ± 0.818
4.43AsnArg: 4.43 ± 1.669
0.0AsnSer: 0.0 ± 0.0
4.43AsnThr: 4.43 ± 1.625
2.215AsnVal: 2.215 ± 1.636
1.107AsnTrp: 1.107 ± 0.829
2.215AsnTyr: 2.215 ± 1.636
0.0AsnXaa: 0.0 ± 0.0
Pro
2.215ProAla: 2.215 ± 1.636
0.0ProCys: 0.0 ± 0.0
2.215ProAsp: 2.215 ± 1.658
1.107ProGlu: 1.107 ± 0.829
2.215ProPhe: 2.215 ± 1.658
7.752ProGly: 7.752 ± 2.433
2.215ProHis: 2.215 ± 1.658
2.215ProIle: 2.215 ± 1.636
3.322ProLys: 3.322 ± 0.84
4.43ProLeu: 4.43 ± 0.022
1.107ProMet: 1.107 ± 0.551
1.107ProAsn: 1.107 ± 0.829
3.322ProPro: 3.322 ± 0.807
1.107ProGln: 1.107 ± 0.818
4.43ProArg: 4.43 ± 0.022
5.537ProSer: 5.537 ± 2.444
0.0ProThr: 0.0 ± 0.0
3.322ProVal: 3.322 ± 2.455
3.322ProTrp: 3.322 ± 0.807
4.43ProTyr: 4.43 ± 0.022
0.0ProXaa: 0.0 ± 0.0
Gln
1.107GlnAla: 1.107 ± 0.818
0.0GlnCys: 0.0 ± 0.0
2.215GlnAsp: 2.215 ± 0.011
1.107GlnGlu: 1.107 ± 0.829
1.107GlnPhe: 1.107 ± 0.818
2.215GlnGly: 2.215 ± 1.636
0.0GlnHis: 0.0 ± 0.0
2.215GlnIle: 2.215 ± 1.636
1.107GlnLys: 1.107 ± 0.829
0.0GlnLeu: 0.0 ± 0.0
1.107GlnMet: 1.107 ± 0.818
2.215GlnAsn: 2.215 ± 1.658
1.107GlnPro: 1.107 ± 0.818
2.215GlnGln: 2.215 ± 1.636
0.0GlnArg: 0.0 ± 0.0
1.107GlnSer: 1.107 ± 0.818
1.107GlnThr: 1.107 ± 0.818
5.537GlnVal: 5.537 ± 0.796
1.107GlnTrp: 1.107 ± 0.818
1.107GlnTyr: 1.107 ± 0.818
0.0GlnXaa: 0.0 ± 0.0
Arg
5.537ArgAla: 5.537 ± 2.498
0.0ArgCys: 0.0 ± 0.0
3.322ArgAsp: 3.322 ± 2.487
2.215ArgGlu: 2.215 ± 0.011
1.107ArgPhe: 1.107 ± 0.829
3.322ArgGly: 3.322 ± 2.455
0.0ArgHis: 0.0 ± 0.0
5.537ArgIle: 5.537 ± 0.796
2.215ArgLys: 2.215 ± 0.011
4.43ArgLeu: 4.43 ± 0.022
0.0ArgMet: 0.0 ± 0.0
1.107ArgAsn: 1.107 ± 0.818
0.0ArgPro: 0.0 ± 0.0
1.107ArgGln: 1.107 ± 0.829
1.107ArgArg: 1.107 ± 0.818
6.645ArgSer: 6.645 ± 1.614
0.0ArgThr: 0.0 ± 0.0
3.322ArgVal: 3.322 ± 2.487
1.107ArgTrp: 1.107 ± 0.829
1.107ArgTyr: 1.107 ± 0.818
0.0ArgXaa: 0.0 ± 0.0
Ser
5.537SerAla: 5.537 ± 0.851
3.322SerCys: 3.322 ± 0.807
1.107SerAsp: 1.107 ± 0.829
5.537SerGlu: 5.537 ± 2.498
4.43SerPhe: 4.43 ± 1.625
7.752SerGly: 7.752 ± 4.08
0.0SerHis: 0.0 ± 0.0
1.107SerIle: 1.107 ± 0.818
8.859SerLys: 8.859 ± 0.044
1.107SerLeu: 1.107 ± 0.829
1.107SerMet: 1.107 ± 0.818
4.43SerAsn: 4.43 ± 0.022
3.322SerPro: 3.322 ± 0.84
4.43SerGln: 4.43 ± 3.273
3.322SerArg: 3.322 ± 2.487
9.967SerSer: 9.967 ± 2.422
8.859SerThr: 8.859 ± 4.898
5.537SerVal: 5.537 ± 0.796
0.0SerTrp: 0.0 ± 0.0
4.43SerTyr: 4.43 ± 1.625
0.0SerXaa: 0.0 ± 0.0
Thr
6.645ThrAla: 6.645 ± 4.909
0.0ThrCys: 0.0 ± 0.0
2.215ThrAsp: 2.215 ± 1.636
2.215ThrGlu: 2.215 ± 1.636
3.322ThrPhe: 3.322 ± 0.807
1.107ThrGly: 1.107 ± 0.829
2.215ThrHis: 2.215 ± 1.658
2.215ThrIle: 2.215 ± 0.011
1.107ThrLys: 1.107 ± 0.818
2.215ThrLeu: 2.215 ± 0.011
1.107ThrMet: 1.107 ± 0.829
1.107ThrAsn: 1.107 ± 0.818
4.43ThrPro: 4.43 ± 3.273
2.215ThrGln: 2.215 ± 0.011
3.322ThrArg: 3.322 ± 2.455
7.752ThrSer: 7.752 ± 4.08
0.0ThrThr: 0.0 ± 0.0
5.537ThrVal: 5.537 ± 0.796
1.107ThrTrp: 1.107 ± 0.829
9.967ThrTyr: 9.967 ± 0.774
0.0ThrXaa: 0.0 ± 0.0
Val
5.537ValAla: 5.537 ± 4.091
3.322ValCys: 3.322 ± 2.487
4.43ValAsp: 4.43 ± 1.669
1.107ValGlu: 1.107 ± 0.829
4.43ValPhe: 4.43 ± 1.669
5.537ValGly: 5.537 ± 2.444
0.0ValHis: 0.0 ± 0.0
0.0ValIle: 0.0 ± 0.0
3.322ValLys: 3.322 ± 0.84
2.215ValLeu: 2.215 ± 1.658
1.107ValMet: 1.107 ± 0.829
6.645ValAsn: 6.645 ± 1.614
3.322ValPro: 3.322 ± 2.455
0.0ValGln: 0.0 ± 0.0
3.322ValArg: 3.322 ± 2.455
8.859ValSer: 8.859 ± 0.044
5.537ValThr: 5.537 ± 2.444
2.215ValVal: 2.215 ± 1.636
0.0ValTrp: 0.0 ± 0.0
1.107ValTyr: 1.107 ± 0.818
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
5.537TrpAsp: 5.537 ± 4.146
1.107TrpGlu: 1.107 ± 0.829
0.0TrpPhe: 0.0 ± 0.0
1.107TrpGly: 1.107 ± 0.818
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.107TrpLys: 1.107 ± 0.829
1.107TrpLeu: 1.107 ± 0.818
0.0TrpMet: 0.0 ± 0.0
2.215TrpAsn: 2.215 ± 1.658
0.0TrpPro: 0.0 ± 0.0
1.107TrpGln: 1.107 ± 0.829
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
1.107TrpThr: 1.107 ± 0.818
2.215TrpVal: 2.215 ± 0.011
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
0.0TyrCys: 0.0 ± 0.0
4.43TyrAsp: 4.43 ± 3.273
1.107TyrGlu: 1.107 ± 0.829
0.0TyrPhe: 0.0 ± 0.0
1.107TyrGly: 1.107 ± 0.818
0.0TyrHis: 0.0 ± 0.0
6.645TyrIle: 6.645 ± 1.68
4.43TyrLys: 4.43 ± 1.669
3.322TyrLeu: 3.322 ± 0.807
1.107TyrMet: 1.107 ± 1.299
2.215TyrAsn: 2.215 ± 0.011
1.107TyrPro: 1.107 ± 0.818
2.215TyrGln: 2.215 ± 0.011
2.215TyrArg: 2.215 ± 0.011
1.107TyrSer: 1.107 ± 0.829
4.43TyrThr: 4.43 ± 3.273
6.645TyrVal: 6.645 ± 4.909
0.0TyrTrp: 0.0 ± 0.0
1.107TyrTyr: 1.107 ± 0.829
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (904 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski