Amino acid dipepetide frequency for Candidatus Propionivibrio aalborgensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.883AlaAla: 12.883 ± 0.165	1.294AlaCys: 1.294 ± 0.035	5.806AlaAsp: 5.806 ± 0.076	6.799AlaGlu: 6.799 ± 0.09	3.891AlaPhe: 3.891 ± 0.064	8.874AlaGly: 8.874 ± 0.113	2.19AlaHis: 2.19 ± 0.043	5.782AlaIle: 5.782 ± 0.093	4.139AlaLys: 4.139 ± 0.075	12.443AlaLeu: 12.443 ± 0.138	2.993AlaMet: 2.993 ± 0.051	3.191AlaAsn: 3.191 ± 0.063	4.343AlaPro: 4.343 ± 0.072	4.091AlaGln: 4.091 ± 0.066	7.316AlaArg: 7.316 ± 0.099	6.184AlaSer: 6.184 ± 0.07	5.49AlaThr: 5.49 ± 0.081	7.621AlaVal: 7.621 ± 0.081	1.452AlaTrp: 1.452 ± 0.039	2.503AlaTyr: 2.503 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	1.1CysAla: 1.1 ± 0.037	0.173CysCys: 0.173 ± 0.013	0.581CysAsp: 0.581 ± 0.023	0.584CysGlu: 0.584 ± 0.023	0.46CysPhe: 0.46 ± 0.021	1.055CysGly: 1.055 ± 0.033	0.346CysHis: 0.346 ± 0.021	0.462CysIle: 0.462 ± 0.021	0.332CysLys: 0.332 ± 0.015	1.046CysLeu: 1.046 ± 0.03	0.223CysMet: 0.223 ± 0.016	0.336CysAsn: 0.336 ± 0.018	0.574CysPro: 0.574 ± 0.027	0.357CysGln: 0.357 ± 0.019	0.741CysArg: 0.741 ± 0.029	0.643CysSer: 0.643 ± 0.025	0.546CysThr: 0.546 ± 0.025	0.71CysVal: 0.71 ± 0.028	0.145CysTrp: 0.145 ± 0.011	0.274CysTyr: 0.274 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	5.993AspAla: 5.993 ± 0.076	0.612AspCys: 0.612 ± 0.022	2.932AspAsp: 2.932 ± 0.069	3.547AspGlu: 3.547 ± 0.074	2.414AspPhe: 2.414 ± 0.053	4.397AspGly: 4.397 ± 0.077	1.081AspHis: 1.081 ± 0.03	2.834AspIle: 2.834 ± 0.052	1.984AspLys: 1.984 ± 0.048	5.482AspLeu: 5.482 ± 0.077	1.179AspMet: 1.179 ± 0.035	1.444AspAsn: 1.444 ± 0.038	2.851AspPro: 2.851 ± 0.053	1.777AspGln: 1.777 ± 0.043	3.347AspArg: 3.347 ± 0.061	3.054AspSer: 3.054 ± 0.05	2.492AspThr: 2.492 ± 0.063	3.623AspVal: 3.623 ± 0.063	0.944AspTrp: 0.944 ± 0.03	1.588AspTyr: 1.588 ± 0.042	0.0AspXaa: 0.0 ± 0.0
Glu	6.407GluAla: 6.407 ± 0.1	0.562GluCys: 0.562 ± 0.021	2.499GluAsp: 2.499 ± 0.052	3.065GluGlu: 3.065 ± 0.06	2.194GluPhe: 2.194 ± 0.047	3.647GluGly: 3.647 ± 0.062	1.394GluHis: 1.394 ± 0.038	3.604GluIle: 3.604 ± 0.061	2.751GluLys: 2.751 ± 0.056	6.438GluLeu: 6.438 ± 0.093	1.603GluMet: 1.603 ± 0.045	1.881GluAsn: 1.881 ± 0.042	2.339GluPro: 2.339 ± 0.05	2.507GluGln: 2.507 ± 0.056	4.607GluArg: 4.607 ± 0.083	3.524GluSer: 3.524 ± 0.058	3.091GluThr: 3.091 ± 0.056	4.059GluVal: 4.059 ± 0.058	0.832GluTrp: 0.832 ± 0.028	1.363GluTyr: 1.363 ± 0.04	0.0GluXaa: 0.0 ± 0.0
Phe	4.269PheAla: 4.269 ± 0.064	0.46PheCys: 0.46 ± 0.023	2.549PheAsp: 2.549 ± 0.053	2.239PheGlu: 2.239 ± 0.044	1.69PhePhe: 1.69 ± 0.044	3.466PheGly: 3.466 ± 0.062	0.803PheHis: 0.803 ± 0.03	1.899PheIle: 1.899 ± 0.047	1.315PheLys: 1.315 ± 0.035	3.615PheLeu: 3.615 ± 0.064	0.816PheMet: 0.816 ± 0.03	1.299PheAsn: 1.299 ± 0.038	1.709PhePro: 1.709 ± 0.042	1.078PheGln: 1.078 ± 0.035	2.255PheArg: 2.255 ± 0.049	2.876PheSer: 2.876 ± 0.057	1.84PheThr: 1.84 ± 0.041	2.999PheVal: 2.999 ± 0.051	0.508PheTrp: 0.508 ± 0.021	1.038PheTyr: 1.038 ± 0.031	0.0PheXaa: 0.0 ± 0.0
Gly	7.31GlyAla: 7.31 ± 0.094	0.983GlyCys: 0.983 ± 0.035	3.999GlyAsp: 3.999 ± 0.089	4.674GlyGlu: 4.674 ± 0.061	3.452GlyPhe: 3.452 ± 0.057	6.094GlyGly: 6.094 ± 0.117	1.797GlyHis: 1.797 ± 0.046	4.739GlyIle: 4.739 ± 0.074	4.023GlyLys: 4.023 ± 0.062	8.125GlyLeu: 8.125 ± 0.104	2.285GlyMet: 2.285 ± 0.048	2.527GlyAsn: 2.527 ± 0.061	2.375GlyPro: 2.375 ± 0.045	2.855GlyGln: 2.855 ± 0.053	5.027GlyArg: 5.027 ± 0.07	4.567GlySer: 4.567 ± 0.068	3.977GlyThr: 3.977 ± 0.07	5.876GlyVal: 5.876 ± 0.076	1.22GlyTrp: 1.22 ± 0.036	2.247GlyTyr: 2.247 ± 0.049	0.0GlyXaa: 0.0 ± 0.0
His	2.317HisAla: 2.317 ± 0.048	0.295HisCys: 0.295 ± 0.019	1.191HisAsp: 1.191 ± 0.034	1.243HisGlu: 1.243 ± 0.032	1.02HisPhe: 1.02 ± 0.03	1.832HisGly: 1.832 ± 0.042	0.614HisHis: 0.614 ± 0.025	1.072HisIle: 1.072 ± 0.028	0.662HisLys: 0.662 ± 0.025	2.341HisLeu: 2.341 ± 0.051	0.448HisMet: 0.448 ± 0.02	0.591HisAsn: 0.591 ± 0.024	1.399HisPro: 1.399 ± 0.04	0.773HisGln: 0.773 ± 0.028	1.507HisArg: 1.507 ± 0.04	1.242HisSer: 1.242 ± 0.038	0.941HisThr: 0.941 ± 0.028	1.437HisVal: 1.437 ± 0.039	0.335HisTrp: 0.335 ± 0.017	0.668HisTyr: 0.668 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	6.382IleAla: 6.382 ± 0.076	0.557IleCys: 0.557 ± 0.024	3.603IleAsp: 3.603 ± 0.06	3.89IleGlu: 3.89 ± 0.068	1.765IlePhe: 1.765 ± 0.043	4.78IleGly: 4.78 ± 0.079	1.067IleHis: 1.067 ± 0.034	2.295IleIle: 2.295 ± 0.047	2.098IleLys: 2.098 ± 0.05	4.729IleLeu: 4.729 ± 0.08	0.96IleMet: 0.96 ± 0.027	1.818IleAsn: 1.818 ± 0.045	2.635IlePro: 2.635 ± 0.049	1.523IleGln: 1.523 ± 0.037	3.352IleArg: 3.352 ± 0.057	3.369IleSer: 3.369 ± 0.062	2.683IleThr: 2.683 ± 0.051	4.121IleVal: 4.121 ± 0.058	0.55IleTrp: 0.55 ± 0.026	1.26IleTyr: 1.26 ± 0.034	0.0IleXaa: 0.0 ± 0.0
Lys	4.096LysAla: 4.096 ± 0.078	0.272LysCys: 0.272 ± 0.018	1.93LysAsp: 1.93 ± 0.046	2.052LysGlu: 2.052 ± 0.051	1.132LysPhe: 1.132 ± 0.036	2.688LysGly: 2.688 ± 0.061	0.885LysHis: 0.885 ± 0.029	2.072LysIle: 2.072 ± 0.053	1.811LysLys: 1.811 ± 0.046	4.251LysLeu: 4.251 ± 0.064	1.071LysMet: 1.071 ± 0.031	1.304LysAsn: 1.304 ± 0.038	2.303LysPro: 2.303 ± 0.053	1.647LysGln: 1.647 ± 0.043	2.734LysArg: 2.734 ± 0.056	2.434LysSer: 2.434 ± 0.053	2.232LysThr: 2.232 ± 0.048	2.651LysVal: 2.651 ± 0.063	0.422LysTrp: 0.422 ± 0.019	0.85LysTyr: 0.85 ± 0.029	0.0LysXaa: 0.0 ± 0.0
Leu	13.373LeuAla: 13.373 ± 0.151	1.105LeuCys: 1.105 ± 0.028	6.11LeuAsp: 6.11 ± 0.087	5.892LeuGlu: 5.892 ± 0.085	3.964LeuPhe: 3.964 ± 0.069	8.041LeuGly: 8.041 ± 0.103	2.234LeuHis: 2.234 ± 0.047	5.732LeuIle: 5.732 ± 0.089	4.214LeuLys: 4.214 ± 0.067	11.862LeuLeu: 11.862 ± 0.155	2.483LeuMet: 2.483 ± 0.045	3.161LeuAsn: 3.161 ± 0.056	5.984LeuPro: 5.984 ± 0.078	3.504LeuGln: 3.504 ± 0.064	7.397LeuArg: 7.397 ± 0.097	6.842LeuSer: 6.842 ± 0.085	5.627LeuThr: 5.627 ± 0.073	7.436LeuVal: 7.436 ± 0.091	1.244LeuTrp: 1.244 ± 0.036	2.309LeuTyr: 2.309 ± 0.047	0.0LeuXaa: 0.0 ± 0.0
Met	2.67MetAla: 2.67 ± 0.046	0.182MetCys: 0.182 ± 0.012	1.111MetAsp: 1.111 ± 0.032	1.137MetGlu: 1.137 ± 0.029	0.733MetPhe: 0.733 ± 0.026	1.678MetGly: 1.678 ± 0.043	0.549MetHis: 0.549 ± 0.021	1.287MetIle: 1.287 ± 0.033	1.222MetLys: 1.222 ± 0.031	2.829MetLeu: 2.829 ± 0.054	0.637MetMet: 0.637 ± 0.024	1.052MetAsn: 1.052 ± 0.033	1.423MetPro: 1.423 ± 0.041	1.024MetGln: 1.024 ± 0.029	1.71MetArg: 1.71 ± 0.044	1.607MetSer: 1.607 ± 0.04	1.488MetThr: 1.488 ± 0.038	1.65MetVal: 1.65 ± 0.039	0.209MetTrp: 0.209 ± 0.016	0.398MetTyr: 0.398 ± 0.021	0.0MetXaa: 0.0 ± 0.0
Asn	3.412AsnAla: 3.412 ± 0.057	0.352AsnCys: 0.352 ± 0.019	1.642AsnAsp: 1.642 ± 0.057	1.68AsnGlu: 1.68 ± 0.039	1.189AsnPhe: 1.189 ± 0.035	2.426AsnGly: 2.426 ± 0.053	0.64AsnHis: 0.64 ± 0.026	1.614AsnIle: 1.614 ± 0.046	1.092AsnLys: 1.092 ± 0.035	3.129AsnLeu: 3.129 ± 0.054	0.699AsnMet: 0.699 ± 0.027	0.942AsnAsn: 0.942 ± 0.03	2.001AsnPro: 2.001 ± 0.047	1.154AsnGln: 1.154 ± 0.036	2.012AsnArg: 2.012 ± 0.046	1.637AsnSer: 1.637 ± 0.041	1.604AsnThr: 1.604 ± 0.043	2.133AsnVal: 2.133 ± 0.046	0.508AsnTrp: 0.508 ± 0.021	0.778AsnTyr: 0.778 ± 0.026	0.0AsnXaa: 0.0 ± 0.0
Pro	5.354ProAla: 5.354 ± 0.081	0.421ProCys: 0.421 ± 0.02	3.15ProAsp: 3.15 ± 0.055	3.595ProGlu: 3.595 ± 0.063	1.775ProPhe: 1.775 ± 0.039	4.052ProGly: 4.052 ± 0.069	0.981ProHis: 0.981 ± 0.027	2.324ProIle: 2.324 ± 0.051	1.783ProLys: 1.783 ± 0.043	4.941ProLeu: 4.941 ± 0.064	1.146ProMet: 1.146 ± 0.034	1.397ProAsn: 1.397 ± 0.042	2.569ProPro: 2.569 ± 0.064	1.804ProGln: 1.804 ± 0.042	2.563ProArg: 2.563 ± 0.052	2.738ProSer: 2.738 ± 0.053	2.33ProThr: 2.33 ± 0.054	3.958ProVal: 3.958 ± 0.076	0.702ProTrp: 0.702 ± 0.028	1.258ProTyr: 1.258 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	4.107GlnAla: 4.107 ± 0.061	0.336GlnCys: 0.336 ± 0.02	1.477GlnAsp: 1.477 ± 0.038	1.803GlnGlu: 1.803 ± 0.045	1.213GlnPhe: 1.213 ± 0.035	2.444GlnGly: 2.444 ± 0.05	0.893GlnHis: 0.893 ± 0.028	2.114GlnIle: 2.114 ± 0.051	1.364GlnLys: 1.364 ± 0.038	4.05GlnLeu: 4.05 ± 0.066	0.988GlnMet: 0.988 ± 0.032	1.05GlnAsn: 1.05 ± 0.029	1.926GlnPro: 1.926 ± 0.048	1.658GlnGln: 1.658 ± 0.051	2.842GlnArg: 2.842 ± 0.049	2.195GlnSer: 2.195 ± 0.048	1.887GlnThr: 1.887 ± 0.047	2.632GlnVal: 2.632 ± 0.055	0.502GlnTrp: 0.502 ± 0.019	0.771GlnTyr: 0.771 ± 0.029	0.0GlnXaa: 0.0 ± 0.0
Arg	6.108ArgAla: 6.108 ± 0.097	0.705ArgCys: 0.705 ± 0.027	3.54ArgAsp: 3.54 ± 0.055	4.252ArgGlu: 4.252 ± 0.063	2.993ArgPhe: 2.993 ± 0.054	4.122ArgGly: 4.122 ± 0.071	1.759ArgHis: 1.759 ± 0.05	4.26ArgIle: 4.26 ± 0.067	2.488ArgLys: 2.488 ± 0.053	8.062ArgLeu: 8.062 ± 0.107	1.775ArgMet: 1.775 ± 0.043	2.226ArgAsn: 2.226 ± 0.043	2.846ArgPro: 2.846 ± 0.056	2.947ArgGln: 2.947 ± 0.056	4.914ArgArg: 4.914 ± 0.092	3.7ArgSer: 3.7 ± 0.056	2.946ArgThr: 2.946 ± 0.051	4.689ArgVal: 4.689 ± 0.066	1.006ArgTrp: 1.006 ± 0.037	1.962ArgTyr: 1.962 ± 0.044	0.0ArgXaa: 0.0 ± 0.0
Ser	6.353SerAla: 6.353 ± 0.077	0.587SerCys: 0.587 ± 0.024	3.115SerAsp: 3.115 ± 0.052	3.369SerGlu: 3.369 ± 0.061	2.411SerPhe: 2.411 ± 0.045	5.811SerGly: 5.811 ± 0.077	1.234SerHis: 1.234 ± 0.033	3.177SerIle: 3.177 ± 0.06	2.103SerLys: 2.103 ± 0.049	6.406SerLeu: 6.406 ± 0.085	1.476SerMet: 1.476 ± 0.038	1.792SerAsn: 1.792 ± 0.046	3.203SerPro: 3.203 ± 0.057	1.946SerGln: 1.946 ± 0.043	3.872SerArg: 3.872 ± 0.064	3.779SerSer: 3.779 ± 0.079	3.138SerThr: 3.138 ± 0.056	4.213SerVal: 4.213 ± 0.069	0.806SerTrp: 0.806 ± 0.024	1.416SerTyr: 1.416 ± 0.038	0.0SerXaa: 0.0 ± 0.0
Thr	5.23ThrAla: 5.23 ± 0.066	0.454ThrCys: 0.454 ± 0.021	2.551ThrAsp: 2.551 ± 0.052	2.511ThrGlu: 2.511 ± 0.054	1.726ThrPhe: 1.726 ± 0.043	4.502ThrGly: 4.502 ± 0.077	1.168ThrHis: 1.168 ± 0.034	2.497ThrIle: 2.497 ± 0.057	1.523ThrLys: 1.523 ± 0.04	6.223ThrLeu: 6.223 ± 0.079	1.136ThrMet: 1.136 ± 0.033	1.354ThrAsn: 1.354 ± 0.039	3.165ThrPro: 3.165 ± 0.061	1.832ThrGln: 1.832 ± 0.043	3.342ThrArg: 3.342 ± 0.056	2.89ThrSer: 2.89 ± 0.052	2.755ThrThr: 2.755 ± 0.063	3.905ThrVal: 3.905 ± 0.057	0.596ThrTrp: 0.596 ± 0.022	1.151ThrTyr: 1.151 ± 0.037	0.0ThrXaa: 0.0 ± 0.0
Val	8.225ValAla: 8.225 ± 0.1	0.825ValCys: 0.825 ± 0.03	3.911ValAsp: 3.911 ± 0.056	4.259ValGlu: 4.259 ± 0.065	3.034ValPhe: 3.034 ± 0.061	5.33ValGly: 5.33 ± 0.074	1.369ValHis: 1.369 ± 0.038	3.987ValIle: 3.987 ± 0.062	2.61ValLys: 2.61 ± 0.054	7.932ValLeu: 7.932 ± 0.09	1.832ValMet: 1.832 ± 0.04	2.159ValAsn: 2.159 ± 0.047	3.292ValPro: 3.292 ± 0.058	2.13ValGln: 2.13 ± 0.044	4.67ValArg: 4.67 ± 0.069	4.669ValSer: 4.669 ± 0.068	3.732ValThr: 3.732 ± 0.06	5.862ValVal: 5.862 ± 0.098	0.91ValTrp: 0.91 ± 0.025	1.491ValTyr: 1.491 ± 0.033	0.0ValXaa: 0.0 ± 0.0
Trp	1.09TrpAla: 1.09 ± 0.032	0.167TrpCys: 0.167 ± 0.013	0.546TrpAsp: 0.546 ± 0.024	0.597TrpGlu: 0.597 ± 0.025	0.554TrpPhe: 0.554 ± 0.025	0.835TrpGly: 0.835 ± 0.027	0.355TrpHis: 0.355 ± 0.02	0.731TrpIle: 0.731 ± 0.029	0.574TrpLys: 0.574 ± 0.025	1.932TrpLeu: 1.932 ± 0.047	0.378TrpMet: 0.378 ± 0.021	0.445TrpAsn: 0.445 ± 0.024	0.63TrpPro: 0.63 ± 0.027	0.672TrpGln: 0.672 ± 0.028	1.137TrpArg: 1.137 ± 0.036	0.8TrpSer: 0.8 ± 0.027	0.549TrpThr: 0.549 ± 0.025	0.965TrpVal: 0.965 ± 0.029	0.253TrpTrp: 0.253 ± 0.016	0.32TrpTyr: 0.32 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.61TyrAla: 2.61 ± 0.053	0.348TyrCys: 0.348 ± 0.018	1.334TyrAsp: 1.334 ± 0.038	1.178TyrGlu: 1.178 ± 0.035	1.111TyrPhe: 1.111 ± 0.033	2.079TyrGly: 2.079 ± 0.053	0.567TyrHis: 0.567 ± 0.021	0.954TyrIle: 0.954 ± 0.032	0.749TyrLys: 0.749 ± 0.027	2.681TyrLeu: 2.681 ± 0.05	0.466TyrMet: 0.466 ± 0.02	0.675TyrAsn: 0.675 ± 0.023	1.272TyrPro: 1.272 ± 0.035	0.972TyrGln: 0.972 ± 0.029	1.957TyrArg: 1.957 ± 0.048	1.458TyrSer: 1.458 ± 0.038	1.162TyrThr: 1.162 ± 0.037	1.692TyrVal: 1.692 ± 0.038	0.384TyrTrp: 0.384 ± 0.019	0.733TyrTyr: 0.733 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3621 proteins (1086514 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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