Amino acid dipepetide frequency for Lettuce chordovirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.573AlaAla: 2.573 ± 1.303
1.103AlaCys: 1.103 ± 0.558
2.94AlaAsp: 2.94 ± 0.913
3.308AlaGlu: 3.308 ± 2.068
4.043AlaPhe: 4.043 ± 0.829
4.778AlaGly: 4.778 ± 1.675
2.205AlaHis: 2.205 ± 0.756
4.778AlaIle: 4.778 ± 1.769
2.94AlaLys: 2.94 ± 1.262
4.41AlaLeu: 4.41 ± 1.513
1.838AlaMet: 1.838 ± 1.907
1.103AlaAsn: 1.103 ± 0.558
1.103AlaPro: 1.103 ± 0.508
1.838AlaGln: 1.838 ± 0.93
4.043AlaArg: 4.043 ± 0.829
5.513AlaSer: 5.513 ± 1.012
4.778AlaThr: 4.778 ± 1.698
4.778AlaVal: 4.778 ± 1.167
0.735AlaTrp: 0.735 ± 0.372
1.47AlaTyr: 1.47 ± 0.977
0.0AlaXaa: 0.0 ± 0.0
Cys
0.735CysAla: 0.735 ± 0.54
0.0CysCys: 0.0 ± 0.0
1.838CysAsp: 1.838 ± 0.93
0.368CysGlu: 0.368 ± 0.186
1.838CysPhe: 1.838 ± 0.433
1.103CysGly: 1.103 ± 0.558
0.0CysHis: 0.0 ± 0.0
1.838CysIle: 1.838 ± 1.054
2.573CysLys: 2.573 ± 0.403
0.735CysLeu: 0.735 ± 0.372
0.0CysMet: 0.0 ± 0.0
1.838CysAsn: 1.838 ± 0.93
0.368CysPro: 0.368 ± 0.186
0.368CysGln: 0.368 ± 0.628
1.838CysArg: 1.838 ± 0.581
1.47CysSer: 1.47 ± 0.744
0.368CysThr: 0.368 ± 0.186
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.675AspAla: 3.675 ± 1.142
1.47AspCys: 1.47 ± 0.744
8.085AspAsp: 8.085 ± 3.737
6.983AspGlu: 6.983 ± 1.484
1.838AspPhe: 1.838 ± 0.581
4.41AspGly: 4.41 ± 1.597
0.368AspHis: 0.368 ± 0.186
2.94AspIle: 2.94 ± 0.424
6.248AspLys: 6.248 ± 0.542
6.983AspLeu: 6.983 ± 2.174
2.94AspMet: 2.94 ± 0.933
3.675AspAsn: 3.675 ± 0.818
3.308AspPro: 3.308 ± 1.229
1.47AspGln: 1.47 ± 1.179
2.94AspArg: 2.94 ± 0.424
5.145AspSer: 5.145 ± 2.032
2.205AspThr: 2.205 ± 1.117
4.043AspVal: 4.043 ± 0.94
1.47AspTrp: 1.47 ± 0.744
2.573AspTyr: 2.573 ± 0.403
0.0AspXaa: 0.0 ± 0.0
Glu
7.35GluAla: 7.35 ± 1.262
0.0GluCys: 0.0 ± 0.0
3.675GluAsp: 3.675 ± 0.641
5.145GluGlu: 5.145 ± 0.764
3.675GluPhe: 3.675 ± 1.06
1.838GluGly: 1.838 ± 0.433
1.47GluHis: 1.47 ± 0.744
3.675GluIle: 3.675 ± 2.5
5.145GluLys: 5.145 ± 0.807
4.778GluLeu: 4.778 ± 1.923
3.308GluMet: 3.308 ± 2.039
2.573GluAsn: 2.573 ± 4.281
1.103GluPro: 1.103 ± 0.474
1.838GluGln: 1.838 ± 0.93
4.41GluArg: 4.41 ± 0.741
5.513GluSer: 5.513 ± 1.756
2.205GluThr: 2.205 ± 1.209
4.043GluVal: 4.043 ± 0.803
0.735GluTrp: 0.735 ± 1.026
1.838GluTyr: 1.838 ± 0.581
0.0GluXaa: 0.0 ± 0.0
Phe
2.94PheAla: 2.94 ± 0.806
1.838PheCys: 1.838 ± 0.93
5.145PheAsp: 5.145 ± 0.807
5.513PheGlu: 5.513 ± 1.981
2.94PhePhe: 2.94 ± 1.262
4.043PheGly: 4.043 ± 0.829
1.47PheHis: 1.47 ± 0.744
3.675PheIle: 3.675 ± 1.142
4.778PheLys: 4.778 ± 1.119
2.94PheLeu: 2.94 ± 0.806
1.103PheMet: 1.103 ± 0.481
3.675PheAsn: 3.675 ± 0.694
2.205PhePro: 2.205 ± 0.962
0.368PheGln: 0.368 ± 0.186
2.205PheArg: 2.205 ± 0.522
4.778PheSer: 4.778 ± 1.035
2.573PheThr: 2.573 ± 1.303
1.103PheVal: 1.103 ± 0.558
0.368PheTrp: 0.368 ± 0.186
1.838PheTyr: 1.838 ± 0.433
0.0PheXaa: 0.0 ± 0.0
Gly
3.675GlyAla: 3.675 ± 0.694
1.838GlyCys: 1.838 ± 0.433
6.248GlyAsp: 6.248 ± 1.873
1.103GlyGlu: 1.103 ± 0.508
1.47GlyPhe: 1.47 ± 0.744
2.573GlyGly: 2.573 ± 0.653
1.47GlyHis: 1.47 ± 0.744
2.94GlyIle: 2.94 ± 0.806
2.94GlyLys: 2.94 ± 0.828
4.41GlyLeu: 4.41 ± 2.145
1.47GlyMet: 1.47 ± 0.744
2.94GlyAsn: 2.94 ± 0.424
1.47GlyPro: 1.47 ± 0.541
2.205GlyGln: 2.205 ± 0.522
3.675GlyArg: 3.675 ± 1.262
5.513GlySer: 5.513 ± 2.746
1.838GlyThr: 1.838 ± 0.631
5.88GlyVal: 5.88 ± 0.99
1.47GlyTrp: 1.47 ± 0.414
1.47GlyTyr: 1.47 ± 0.744
0.0GlyXaa: 0.0 ± 0.0
His
1.103HisAla: 1.103 ± 0.558
0.0HisCys: 0.0 ± 0.0
1.47HisAsp: 1.47 ± 0.744
0.735HisGlu: 0.735 ± 0.59
1.47HisPhe: 1.47 ± 0.414
1.103HisGly: 1.103 ± 0.474
0.368HisHis: 0.368 ± 0.186
1.103HisIle: 1.103 ± 0.474
1.47HisLys: 1.47 ± 0.414
1.103HisLeu: 1.103 ± 0.558
0.368HisMet: 0.368 ± 0.735
0.368HisAsn: 0.368 ± 0.186
0.735HisPro: 0.735 ± 0.372
1.47HisGln: 1.47 ± 1.077
1.103HisArg: 1.103 ± 0.985
2.573HisSer: 2.573 ± 1.303
0.0HisThr: 0.0 ± 0.0
2.573HisVal: 2.573 ± 0.903
0.0HisTrp: 0.0 ± 0.0
1.103HisTyr: 1.103 ± 0.558
0.0HisXaa: 0.0 ± 0.0
Ile
2.94IleAla: 2.94 ± 1.062
1.103IleCys: 1.103 ± 0.474
4.778IleAsp: 4.778 ± 1.167
5.88IleGlu: 5.88 ± 0.454
2.94IlePhe: 2.94 ± 0.913
4.043IleGly: 4.043 ± 1.318
1.47IleHis: 1.47 ± 0.414
2.94IleIle: 2.94 ± 0.424
6.983IleLys: 6.983 ± 1.267
5.145IleLeu: 5.145 ± 1.843
2.205IleMet: 2.205 ± 0.522
4.41IleAsn: 4.41 ± 1.874
1.103IlePro: 1.103 ± 0.474
2.94IleGln: 2.94 ± 1.758
3.675IleArg: 3.675 ± 0.865
2.94IleSer: 2.94 ± 0.984
1.103IleThr: 1.103 ± 0.474
2.573IleVal: 2.573 ± 2.796
0.368IleTrp: 0.368 ± 0.186
3.308IleTyr: 3.308 ± 1.387
0.0IleXaa: 0.0 ± 0.0
Lys
5.145LysAla: 5.145 ± 2.111
2.573LysCys: 2.573 ± 0.903
3.675LysAsp: 3.675 ± 0.648
6.248LysGlu: 6.248 ± 1.973
3.675LysPhe: 3.675 ± 1.06
5.513LysGly: 5.513 ± 2.038
1.838LysHis: 1.838 ± 0.433
5.513LysIle: 5.513 ± 1.964
8.82LysLys: 8.82 ± 5.634
11.025LysLeu: 11.025 ± 5.262
2.205LysMet: 2.205 ± 1.757
3.308LysAsn: 3.308 ± 0.826
1.47LysPro: 1.47 ± 0.414
1.103LysGln: 1.103 ± 0.888
4.778LysArg: 4.778 ± 1.769
4.778LysSer: 4.778 ± 1.341
2.94LysThr: 2.94 ± 1.489
6.248LysVal: 6.248 ± 1.186
0.368LysTrp: 0.368 ± 0.186
1.838LysTyr: 1.838 ± 0.631
0.0LysXaa: 0.0 ± 0.0
Leu
5.145LeuAla: 5.145 ± 1.843
1.47LeuCys: 1.47 ± 0.541
5.88LeuAsp: 5.88 ± 0.545
4.043LeuGlu: 4.043 ± 3.04
6.983LeuPhe: 6.983 ± 1.346
2.94LeuGly: 2.94 ± 1.083
0.735LeuHis: 0.735 ± 0.372
8.453LeuIle: 8.453 ± 1.446
8.82LeuLys: 8.82 ± 4.892
6.983LeuLeu: 6.983 ± 0.655
2.94LeuMet: 2.94 ± 0.83
7.35LeuAsn: 7.35 ± 0.485
1.47LeuPro: 1.47 ± 0.541
2.94LeuGln: 2.94 ± 0.806
5.88LeuArg: 5.88 ± 1.347
9.555LeuSer: 9.555 ± 1.928
3.675LeuThr: 3.675 ± 1.161
3.675LeuVal: 3.675 ± 0.694
0.0LeuTrp: 0.0 ± 0.0
0.735LeuTyr: 0.735 ± 0.372
0.0LeuXaa: 0.0 ± 0.0
Met
4.043MetAla: 4.043 ± 1.318
0.368MetCys: 0.368 ± 0.186
2.205MetAsp: 2.205 ± 0.522
2.573MetGlu: 2.573 ± 0.849
2.94MetPhe: 2.94 ± 0.806
2.205MetGly: 2.205 ± 0.464
0.735MetHis: 0.735 ± 1.026
1.103MetIle: 1.103 ± 0.474
3.308MetLys: 3.308 ± 1.229
1.103MetLeu: 1.103 ± 0.888
0.735MetMet: 0.735 ± 0.59
1.838MetAsn: 1.838 ± 1.269
0.735MetPro: 0.735 ± 0.372
1.47MetGln: 1.47 ± 0.414
3.675MetArg: 3.675 ± 3.497
3.675MetSer: 3.675 ± 2.597
1.103MetThr: 1.103 ± 0.508
0.735MetVal: 0.735 ± 0.372
0.0MetTrp: 0.0 ± 0.0
0.735MetTyr: 0.735 ± 0.54
0.0MetXaa: 0.0 ± 0.0
Asn
1.47AsnAla: 1.47 ± 0.414
0.735AsnCys: 0.735 ± 0.59
4.043AsnAsp: 4.043 ± 0.615
1.838AsnGlu: 1.838 ± 0.93
3.308AsnPhe: 3.308 ± 0.971
2.205AsnGly: 2.205 ± 1.117
1.103AsnHis: 1.103 ± 0.474
4.41AsnIle: 4.41 ± 1.876
2.573AsnLys: 2.573 ± 1.966
5.145AsnLeu: 5.145 ± 2.855
2.94AsnMet: 2.94 ± 1.262
2.94AsnAsn: 2.94 ± 1.062
1.103AsnPro: 1.103 ± 0.474
1.103AsnGln: 1.103 ± 0.985
4.41AsnArg: 4.41 ± 1.211
3.675AsnSer: 3.675 ± 0.911
1.838AsnThr: 1.838 ± 0.433
3.675AsnVal: 3.675 ± 1.906
0.368AsnTrp: 0.368 ± 0.186
1.103AsnTyr: 1.103 ± 0.558
0.0AsnXaa: 0.0 ± 0.0
Pro
1.103ProAla: 1.103 ± 0.474
0.368ProCys: 0.368 ± 0.735
2.573ProAsp: 2.573 ± 1.153
1.838ProGlu: 1.838 ± 0.631
1.103ProPhe: 1.103 ± 0.508
0.735ProGly: 0.735 ± 0.372
0.368ProHis: 0.368 ± 0.628
2.205ProIle: 2.205 ± 0.949
1.838ProLys: 1.838 ± 0.93
2.94ProLeu: 2.94 ± 0.913
1.103ProMet: 1.103 ± 0.474
0.368ProAsn: 0.368 ± 0.186
0.368ProPro: 0.368 ± 0.186
0.368ProGln: 0.368 ± 0.628
0.735ProArg: 0.735 ± 0.372
1.838ProSer: 1.838 ± 0.93
0.368ProThr: 0.368 ± 0.735
4.043ProVal: 4.043 ± 1.575
0.0ProTrp: 0.0 ± 0.0
0.735ProTyr: 0.735 ± 0.372
0.0ProXaa: 0.0 ± 0.0
Gln
2.573GlnAla: 2.573 ± 0.403
0.368GlnCys: 0.368 ± 0.186
3.308GlnAsp: 3.308 ± 1.423
0.735GlnGlu: 0.735 ± 0.59
2.205GlnPhe: 2.205 ± 1.117
1.47GlnGly: 1.47 ± 1.179
0.368GlnHis: 0.368 ± 0.735
1.47GlnIle: 1.47 ± 0.977
2.205GlnLys: 2.205 ± 1.117
4.778GlnLeu: 4.778 ± 1.3
1.838GlnMet: 1.838 ± 1.829
1.103GlnAsn: 1.103 ± 0.474
0.368GlnPro: 0.368 ± 0.186
0.735GlnGln: 0.735 ± 0.372
1.103GlnArg: 1.103 ± 0.474
2.94GlnSer: 2.94 ± 1.345
1.103GlnThr: 1.103 ± 0.508
1.838GlnVal: 1.838 ± 0.631
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
6.248ArgAla: 6.248 ± 1.639
0.368ArgCys: 0.368 ± 0.628
3.308ArgAsp: 3.308 ± 0.515
2.94ArgGlu: 2.94 ± 0.826
2.573ArgPhe: 2.573 ± 0.871
2.94ArgGly: 2.94 ± 3.871
1.47ArgHis: 1.47 ± 0.744
3.308ArgIle: 3.308 ± 1.182
5.88ArgLys: 5.88 ± 1.215
5.88ArgLeu: 5.88 ± 2.221
2.205ArgMet: 2.205 ± 0.756
2.573ArgAsn: 2.573 ± 0.903
0.735ArgPro: 0.735 ± 0.59
1.47ArgGln: 1.47 ± 1.179
2.205ArgArg: 2.205 ± 1.015
3.675ArgSer: 3.675 ± 1.066
1.838ArgThr: 1.838 ± 1.054
2.94ArgVal: 2.94 ± 1.062
1.103ArgTrp: 1.103 ± 1.319
2.573ArgTyr: 2.573 ± 0.403
0.0ArgXaa: 0.0 ± 0.0
Ser
2.573SerAla: 2.573 ± 0.961
1.838SerCys: 1.838 ± 0.433
4.778SerAsp: 4.778 ± 0.723
5.88SerGlu: 5.88 ± 0.854
4.41SerPhe: 4.41 ± 1.043
7.718SerGly: 7.718 ± 1.995
1.838SerHis: 1.838 ± 0.998
4.043SerIle: 4.043 ± 1.318
4.778SerLys: 4.778 ± 1.777
9.188SerLeu: 9.188 ± 1.005
2.573SerMet: 2.573 ± 0.961
2.205SerAsn: 2.205 ± 1.769
2.205SerPro: 2.205 ± 0.464
3.675SerGln: 3.675 ± 1.161
2.94SerArg: 2.94 ± 2.218
8.085SerSer: 8.085 ± 1.647
6.248SerThr: 6.248 ± 1.799
5.513SerVal: 5.513 ± 1.018
0.368SerTrp: 0.368 ± 0.186
4.043SerTyr: 4.043 ± 1.575
0.0SerXaa: 0.0 ± 0.0
Thr
0.368ThrAla: 0.368 ± 0.628
0.0ThrCys: 0.0 ± 0.0
1.838ThrAsp: 1.838 ± 0.581
4.043ThrGlu: 4.043 ± 1.035
4.778ThrPhe: 4.778 ± 1.675
2.94ThrGly: 2.94 ± 1.489
0.368ThrHis: 0.368 ± 0.186
2.573ThrIle: 2.573 ± 1.303
1.838ThrLys: 1.838 ± 0.581
4.41ThrLeu: 4.41 ± 1.217
1.103ThrMet: 1.103 ± 1.175
0.735ThrAsn: 0.735 ± 0.372
0.735ThrPro: 0.735 ± 0.372
1.47ThrGln: 1.47 ± 0.541
2.94ThrArg: 2.94 ± 0.424
4.41ThrSer: 4.41 ± 0.88
2.205ThrThr: 2.205 ± 1.117
0.735ThrVal: 0.735 ± 0.59
0.735ThrTrp: 0.735 ± 0.372
0.368ThrTyr: 0.368 ± 0.186
0.0ThrXaa: 0.0 ± 0.0
Val
5.145ValAla: 5.145 ± 0.807
1.47ValCys: 1.47 ± 0.541
4.41ValAsp: 4.41 ± 1.597
2.94ValGlu: 2.94 ± 0.913
2.205ValPhe: 2.205 ± 1.117
1.838ValGly: 1.838 ± 1.054
0.735ValHis: 0.735 ± 0.59
3.308ValIle: 3.308 ± 0.851
7.718ValLys: 7.718 ± 1.059
4.778ValLeu: 4.778 ± 1.698
1.838ValMet: 1.838 ± 0.631
4.41ValAsn: 4.41 ± 1.217
1.838ValPro: 1.838 ± 0.433
2.573ValGln: 2.573 ± 0.403
2.205ValArg: 2.205 ± 1.117
5.145ValSer: 5.145 ± 1.856
1.838ValThr: 1.838 ± 1.054
5.145ValVal: 5.145 ± 1.788
0.368ValTrp: 0.368 ± 0.186
1.103ValTyr: 1.103 ± 0.474
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.368TrpCys: 0.368 ± 0.186
0.368TrpAsp: 0.368 ± 0.735
0.368TrpGlu: 0.368 ± 0.186
0.368TrpPhe: 0.368 ± 0.186
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.368TrpIle: 0.368 ± 0.186
0.735TrpLys: 0.735 ± 1.026
1.47TrpLeu: 1.47 ± 1.179
0.735TrpMet: 0.735 ± 0.372
1.103TrpAsn: 1.103 ± 0.558
0.735TrpPro: 0.735 ± 0.372
0.368TrpGln: 0.368 ± 0.186
0.368TrpArg: 0.368 ± 0.186
1.103TrpSer: 1.103 ± 0.558
0.0TrpThr: 0.0 ± 0.0
0.368TrpVal: 0.368 ± 0.186
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.47TyrAla: 1.47 ± 0.977
0.0TyrCys: 0.0 ± 0.0
2.573TyrAsp: 2.573 ± 0.903
1.838TyrGlu: 1.838 ± 0.93
0.735TyrPhe: 0.735 ± 0.59
2.205TyrGly: 2.205 ± 1.117
1.838TyrHis: 1.838 ± 0.93
2.205TyrIle: 2.205 ± 1.117
1.47TyrLys: 1.47 ± 0.414
1.47TyrLeu: 1.47 ± 0.541
1.47TyrMet: 1.47 ± 0.541
1.47TyrAsn: 1.47 ± 1.435
1.838TyrPro: 1.838 ± 0.433
0.735TyrGln: 0.735 ± 0.54
1.103TyrArg: 1.103 ± 0.558
2.573TyrSer: 2.573 ± 0.403
0.368TyrThr: 0.368 ± 0.186
1.103TyrVal: 1.103 ± 0.558
0.368TyrTrp: 0.368 ± 0.186
0.368TyrTyr: 0.368 ± 0.628
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (2722 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski