Amino acid dipepetide frequency for Suttonella ornithocola

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.599AlaAla: 8.599 ± 0.151
0.891AlaCys: 0.891 ± 0.037
4.771AlaAsp: 4.771 ± 0.113
6.094AlaGlu: 6.094 ± 0.119
3.668AlaPhe: 3.668 ± 0.074
5.814AlaGly: 5.814 ± 0.113
1.918AlaHis: 1.918 ± 0.05
6.993AlaIle: 6.993 ± 0.112
5.355AlaLys: 5.355 ± 0.091
11.002AlaLeu: 11.002 ± 0.147
2.276AlaMet: 2.276 ± 0.061
3.696AlaAsn: 3.696 ± 0.098
2.882AlaPro: 2.882 ± 0.08
4.886AlaGln: 4.886 ± 0.121
4.094AlaArg: 4.094 ± 0.084
4.392AlaSer: 4.392 ± 0.097
4.408AlaThr: 4.408 ± 0.101
5.673AlaVal: 5.673 ± 0.1
1.098AlaTrp: 1.098 ± 0.037
2.954AlaTyr: 2.954 ± 0.066
0.0AlaXaa: 0.0 ± 0.0
Cys
0.869CysAla: 0.869 ± 0.034
0.152CysCys: 0.152 ± 0.016
0.477CysAsp: 0.477 ± 0.027
0.522CysGlu: 0.522 ± 0.028
0.423CysPhe: 0.423 ± 0.024
0.938CysGly: 0.938 ± 0.041
0.371CysHis: 0.371 ± 0.021
0.613CysIle: 0.613 ± 0.028
0.314CysLys: 0.314 ± 0.022
0.984CysLeu: 0.984 ± 0.041
0.16CysMet: 0.16 ± 0.016
0.278CysAsn: 0.278 ± 0.019
0.433CysPro: 0.433 ± 0.028
0.481CysGln: 0.481 ± 0.026
0.468CysArg: 0.468 ± 0.03
0.606CysSer: 0.606 ± 0.031
0.396CysThr: 0.396 ± 0.022
0.522CysVal: 0.522 ± 0.031
0.096CysTrp: 0.096 ± 0.011
0.405CysTyr: 0.405 ± 0.027
0.0CysXaa: 0.0 ± 0.0
Asp
4.409AspAla: 4.409 ± 0.088
0.578AspCys: 0.578 ± 0.031
2.705AspAsp: 2.705 ± 0.072
3.393AspGlu: 3.393 ± 0.071
2.268AspPhe: 2.268 ± 0.058
3.635AspGly: 3.635 ± 0.149
0.924AspHis: 0.924 ± 0.036
4.474AspIle: 4.474 ± 0.09
3.449AspLys: 3.449 ± 0.08
4.669AspLeu: 4.669 ± 0.085
1.08AspMet: 1.08 ± 0.039
2.746AspAsn: 2.746 ± 0.077
1.818AspPro: 1.818 ± 0.052
1.281AspGln: 1.281 ± 0.048
2.022AspArg: 2.022 ± 0.053
2.784AspSer: 2.784 ± 0.093
2.878AspThr: 2.878 ± 0.076
2.953AspVal: 2.953 ± 0.106
0.846AspTrp: 0.846 ± 0.033
2.072AspTyr: 2.072 ± 0.058
0.0AspXaa: 0.0 ± 0.0
Glu
5.658GluAla: 5.658 ± 0.111
0.508GluCys: 0.508 ± 0.029
2.632GluAsp: 2.632 ± 0.072
3.824GluGlu: 3.824 ± 0.1
1.68GluPhe: 1.68 ± 0.06
3.225GluGly: 3.225 ± 0.062
1.623GluHis: 1.623 ± 0.049
4.543GluIle: 4.543 ± 0.082
5.032GluLys: 5.032 ± 0.109
5.4GluLeu: 5.4 ± 0.099
1.68GluMet: 1.68 ± 0.05
3.5GluAsn: 3.5 ± 0.081
1.897GluPro: 1.897 ± 0.06
3.795GluGln: 3.795 ± 0.088
3.449GluArg: 3.449 ± 0.085
2.991GluSer: 2.991 ± 0.069
3.518GluThr: 3.518 ± 0.074
3.424GluVal: 3.424 ± 0.087
0.758GluTrp: 0.758 ± 0.034
1.7GluTyr: 1.7 ± 0.051
0.0GluXaa: 0.0 ± 0.0
Phe
3.769PheAla: 3.769 ± 0.085
0.461PheCys: 0.461 ± 0.026
2.147PheAsp: 2.147 ± 0.061
2.001PheGlu: 2.001 ± 0.056
1.892PhePhe: 1.892 ± 0.061
2.899PheGly: 2.899 ± 0.069
0.962PheHis: 0.962 ± 0.035
3.017PheIle: 3.017 ± 0.075
1.76PheLys: 1.76 ± 0.048
4.044PheLeu: 4.044 ± 0.101
0.87PheMet: 0.87 ± 0.035
1.81PheAsn: 1.81 ± 0.055
1.555PhePro: 1.555 ± 0.055
1.27PheGln: 1.27 ± 0.048
1.579PheArg: 1.579 ± 0.05
3.341PheSer: 3.341 ± 0.074
2.333PheThr: 2.333 ± 0.053
2.182PheVal: 2.182 ± 0.062
0.619PheTrp: 0.619 ± 0.035
1.537PheTyr: 1.537 ± 0.048
0.0PheXaa: 0.0 ± 0.0
Gly
5.247GlyAla: 5.247 ± 0.114
0.744GlyCys: 0.744 ± 0.035
3.241GlyAsp: 3.241 ± 0.117
4.537GlyGlu: 4.537 ± 0.079
3.033GlyPhe: 3.033 ± 0.072
4.876GlyGly: 4.876 ± 0.131
1.465GlyHis: 1.465 ± 0.044
5.378GlyIle: 5.378 ± 0.093
4.548GlyLys: 4.548 ± 0.096
6.475GlyLeu: 6.475 ± 0.116
1.826GlyMet: 1.826 ± 0.057
2.901GlyAsn: 2.901 ± 0.116
1.084GlyPro: 1.084 ± 0.043
2.784GlyGln: 2.784 ± 0.07
2.853GlyArg: 2.853 ± 0.067
3.687GlySer: 3.687 ± 0.096
3.159GlyThr: 3.159 ± 0.088
4.298GlyVal: 4.298 ± 0.093
0.901GlyTrp: 0.901 ± 0.036
2.607GlyTyr: 2.607 ± 0.069
0.0GlyXaa: 0.0 ± 0.0
His
1.731HisAla: 1.731 ± 0.047
0.287HisCys: 0.287 ± 0.021
0.973HisAsp: 0.973 ± 0.039
1.212HisGlu: 1.212 ± 0.043
1.031HisPhe: 1.031 ± 0.039
1.646HisGly: 1.646 ± 0.051
0.823HisHis: 0.823 ± 0.037
1.689HisIle: 1.689 ± 0.048
1.097HisLys: 1.097 ± 0.041
2.569HisLeu: 2.569 ± 0.063
0.404HisMet: 0.404 ± 0.022
0.918HisAsn: 0.918 ± 0.037
1.486HisPro: 1.486 ± 0.047
1.386HisGln: 1.386 ± 0.047
1.309HisArg: 1.309 ± 0.048
1.407HisSer: 1.407 ± 0.047
1.226HisThr: 1.226 ± 0.041
0.976HisVal: 0.976 ± 0.04
0.519HisTrp: 0.519 ± 0.028
1.109HisTyr: 1.109 ± 0.041
0.0HisXaa: 0.0 ± 0.0
Ile
7.507IleAla: 7.507 ± 0.133
0.778IleCys: 0.778 ± 0.034
4.613IleAsp: 4.613 ± 0.078
5.083IleGlu: 5.083 ± 0.105
3.093IlePhe: 3.093 ± 0.078
5.552IleGly: 5.552 ± 0.111
1.653IleHis: 1.653 ± 0.052
5.299IleIle: 5.299 ± 0.103
3.384IleLys: 3.384 ± 0.072
6.695IleLeu: 6.695 ± 0.129
1.419IleMet: 1.419 ± 0.043
3.211IleAsn: 3.211 ± 0.075
3.068IlePro: 3.068 ± 0.07
2.818IleGln: 2.818 ± 0.059
3.512IleArg: 3.512 ± 0.075
4.598IleSer: 4.598 ± 0.089
4.07IleThr: 4.07 ± 0.089
4.453IleVal: 4.453 ± 0.083
0.728IleTrp: 0.728 ± 0.034
2.255IleTyr: 2.255 ± 0.067
0.0IleXaa: 0.0 ± 0.0
Lys
5.434LysAla: 5.434 ± 0.116
0.284LysCys: 0.284 ± 0.018
3.006LysAsp: 3.006 ± 0.08
3.59LysGlu: 3.59 ± 0.073
1.441LysPhe: 1.441 ± 0.048
3.449LysGly: 3.449 ± 0.071
1.215LysHis: 1.215 ± 0.046
4.174LysIle: 4.174 ± 0.096
3.466LysLys: 3.466 ± 0.09
4.842LysLeu: 4.842 ± 0.099
1.606LysMet: 1.606 ± 0.055
3.29LysAsn: 3.29 ± 0.076
2.237LysPro: 2.237 ± 0.071
3.017LysGln: 3.017 ± 0.074
3.092LysArg: 3.092 ± 0.08
3.037LysSer: 3.037 ± 0.067
3.651LysThr: 3.651 ± 0.1
3.223LysVal: 3.223 ± 0.072
0.583LysTrp: 0.583 ± 0.03
1.568LysTyr: 1.568 ± 0.045
0.0LysXaa: 0.0 ± 0.0
Leu
9.839LeuAla: 9.839 ± 0.151
1.08LeuCys: 1.08 ± 0.048
4.984LeuAsp: 4.984 ± 0.101
5.751LeuGlu: 5.751 ± 0.112
4.281LeuPhe: 4.281 ± 0.099
6.517LeuGly: 6.517 ± 0.109
2.065LeuHis: 2.065 ± 0.056
7.389LeuIle: 7.389 ± 0.125
5.765LeuLys: 5.765 ± 0.103
11.008LeuLeu: 11.008 ± 0.193
2.565LeuMet: 2.565 ± 0.062
4.802LeuAsn: 4.802 ± 0.088
5.593LeuPro: 5.593 ± 0.103
4.111LeuGln: 4.111 ± 0.093
4.648LeuArg: 4.648 ± 0.108
8.089LeuSer: 8.089 ± 0.12
6.136LeuThr: 6.136 ± 0.105
5.405LeuVal: 5.405 ± 0.101
1.382LeuTrp: 1.382 ± 0.047
3.057LeuTyr: 3.057 ± 0.078
0.0LeuXaa: 0.0 ± 0.0
Met
2.067MetAla: 2.067 ± 0.055
0.181MetCys: 0.181 ± 0.016
1.242MetAsp: 1.242 ± 0.045
1.043MetGlu: 1.043 ± 0.041
0.748MetPhe: 0.748 ± 0.034
1.497MetGly: 1.497 ± 0.054
0.463MetHis: 0.463 ± 0.029
1.663MetIle: 1.663 ± 0.055
1.493MetLys: 1.493 ± 0.052
2.524MetLeu: 2.524 ± 0.06
0.669MetMet: 0.669 ± 0.032
1.098MetAsn: 1.098 ± 0.04
1.164MetPro: 1.164 ± 0.043
1.271MetGln: 1.271 ± 0.045
1.388MetArg: 1.388 ± 0.049
1.486MetSer: 1.486 ± 0.048
1.572MetThr: 1.572 ± 0.046
1.316MetVal: 1.316 ± 0.046
0.276MetTrp: 0.276 ± 0.021
0.405MetTyr: 0.405 ± 0.024
0.0MetXaa: 0.0 ± 0.0
Asn
4.215AsnAla: 4.215 ± 0.093
0.416AsnCys: 0.416 ± 0.023
2.389AsnAsp: 2.389 ± 0.095
2.43AsnGlu: 2.43 ± 0.064
1.538AsnPhe: 1.538 ± 0.056
3.403AsnGly: 3.403 ± 0.1
1.296AsnHis: 1.296 ± 0.048
3.512AsnIle: 3.512 ± 0.077
2.171AsnLys: 2.171 ± 0.068
4.079AsnLeu: 4.079 ± 0.085
0.855AsnMet: 0.855 ± 0.031
2.139AsnAsn: 2.139 ± 0.065
2.517AsnPro: 2.517 ± 0.076
2.16AsnGln: 2.16 ± 0.066
2.165AsnArg: 2.165 ± 0.051
2.487AsnSer: 2.487 ± 0.075
2.614AsnThr: 2.614 ± 0.084
2.188AsnVal: 2.188 ± 0.061
0.644AsnTrp: 0.644 ± 0.035
1.471AsnTyr: 1.471 ± 0.057
0.0AsnXaa: 0.0 ± 0.0
Pro
3.273ProAla: 3.273 ± 0.106
0.299ProCys: 0.299 ± 0.022
2.372ProAsp: 2.372 ± 0.056
3.298ProGlu: 3.298 ± 0.076
1.725ProPhe: 1.725 ± 0.051
1.847ProGly: 1.847 ± 0.048
1.012ProHis: 1.012 ± 0.036
3.099ProIle: 3.099 ± 0.069
2.482ProLys: 2.482 ± 0.064
4.179ProLeu: 4.179 ± 0.081
0.89ProMet: 0.89 ± 0.035
2.072ProAsn: 2.072 ± 0.055
1.632ProPro: 1.632 ± 0.065
1.793ProGln: 1.793 ± 0.056
1.374ProArg: 1.374 ± 0.051
2.372ProSer: 2.372 ± 0.058
2.389ProThr: 2.389 ± 0.058
2.612ProVal: 2.612 ± 0.071
0.503ProTrp: 0.503 ± 0.031
1.59ProTyr: 1.59 ± 0.048
0.0ProXaa: 0.0 ± 0.0
Gln
4.906GlnAla: 4.906 ± 0.114
0.344GlnCys: 0.344 ± 0.024
1.902GlnAsp: 1.902 ± 0.073
2.617GlnGlu: 2.617 ± 0.077
1.832GlnPhe: 1.832 ± 0.055
2.6GlnGly: 2.6 ± 0.069
1.194GlnHis: 1.194 ± 0.051
3.185GlnIle: 3.185 ± 0.067
3.059GlnLys: 3.059 ± 0.067
4.929GlnLeu: 4.929 ± 0.096
1.132GlnMet: 1.132 ± 0.04
2.05GlnAsn: 2.05 ± 0.069
1.878GlnPro: 1.878 ± 0.052
2.906GlnGln: 2.906 ± 0.084
2.387GlnArg: 2.387 ± 0.077
3.093GlnSer: 3.093 ± 0.074
3.079GlnThr: 3.079 ± 0.078
2.408GlnVal: 2.408 ± 0.06
0.77GlnTrp: 0.77 ± 0.033
1.707GlnTyr: 1.707 ± 0.052
0.0GlnXaa: 0.0 ± 0.0
Arg
3.791ArgAla: 3.791 ± 0.094
0.404ArgCys: 0.404 ± 0.025
2.181ArgAsp: 2.181 ± 0.071
3.485ArgGlu: 3.485 ± 0.083
2.278ArgPhe: 2.278 ± 0.074
2.66ArgGly: 2.66 ± 0.054
1.239ArgHis: 1.239 ± 0.044
3.137ArgIle: 3.137 ± 0.073
2.572ArgLys: 2.572 ± 0.073
5.777ArgLeu: 5.777 ± 0.111
1.312ArgMet: 1.312 ± 0.047
1.718ArgAsn: 1.718 ± 0.056
1.873ArgPro: 1.873 ± 0.055
2.684ArgGln: 2.684 ± 0.07
2.708ArgArg: 2.708 ± 0.071
2.366ArgSer: 2.366 ± 0.057
2.02ArgThr: 2.02 ± 0.048
2.636ArgVal: 2.636 ± 0.074
0.703ArgTrp: 0.703 ± 0.029
2.056ArgTyr: 2.056 ± 0.057
0.0ArgXaa: 0.0 ± 0.0
Ser
5.746SerAla: 5.746 ± 0.12
0.479SerCys: 0.479 ± 0.027
3.415SerAsp: 3.415 ± 0.07
3.598SerGlu: 3.598 ± 0.091
2.321SerPhe: 2.321 ± 0.061
4.363SerGly: 4.363 ± 0.102
1.496SerHis: 1.496 ± 0.043
4.162SerIle: 4.162 ± 0.099
2.898SerLys: 2.898 ± 0.075
6.192SerLeu: 6.192 ± 0.115
1.301SerMet: 1.301 ± 0.043
2.34SerAsn: 2.34 ± 0.073
2.494SerPro: 2.494 ± 0.062
2.835SerGln: 2.835 ± 0.079
2.663SerArg: 2.663 ± 0.07
3.331SerSer: 3.331 ± 0.09
3.154SerThr: 3.154 ± 0.099
3.888SerVal: 3.888 ± 0.097
0.709SerTrp: 0.709 ± 0.034
1.929SerTyr: 1.929 ± 0.054
0.0SerXaa: 0.0 ± 0.0
Thr
5.443ThrAla: 5.443 ± 0.153
0.391ThrCys: 0.391 ± 0.024
2.697ThrAsp: 2.697 ± 0.066
3.024ThrGlu: 3.024 ± 0.068
2.216ThrPhe: 2.216 ± 0.059
3.778ThrGly: 3.778 ± 0.122
1.517ThrHis: 1.517 ± 0.051
3.992ThrIle: 3.992 ± 0.101
2.313ThrLys: 2.313 ± 0.071
6.992ThrLeu: 6.992 ± 0.112
1.005ThrMet: 1.005 ± 0.035
2.034ThrAsn: 2.034 ± 0.071
2.993ThrPro: 2.993 ± 0.097
2.625ThrGln: 2.625 ± 0.074
2.25ThrArg: 2.25 ± 0.06
2.66ThrSer: 2.66 ± 0.067
2.902ThrThr: 2.902 ± 0.078
3.597ThrVal: 3.597 ± 0.101
0.574ThrTrp: 0.574 ± 0.031
1.607ThrTyr: 1.607 ± 0.049
0.0ThrXaa: 0.0 ± 0.0
Val
5.129ValAla: 5.129 ± 0.091
0.681ValCys: 0.681 ± 0.03
2.991ValAsp: 2.991 ± 0.084
3.283ValGlu: 3.283 ± 0.08
2.483ValPhe: 2.483 ± 0.062
3.851ValGly: 3.851 ± 0.076
1.123ValHis: 1.123 ± 0.038
4.617ValIle: 4.617 ± 0.085
3.121ValLys: 3.121 ± 0.09
6.046ValLeu: 6.046 ± 0.117
1.668ValMet: 1.668 ± 0.051
2.614ValAsn: 2.614 ± 0.078
2.251ValPro: 2.251 ± 0.069
2.064ValGln: 2.064 ± 0.057
2.732ValArg: 2.732 ± 0.064
3.886ValSer: 3.886 ± 0.104
2.998ValThr: 2.998 ± 0.14
3.904ValVal: 3.904 ± 0.102
0.71ValTrp: 0.71 ± 0.035
1.849ValTyr: 1.849 ± 0.053
0.0ValXaa: 0.0 ± 0.0
Trp
0.965TrpAla: 0.965 ± 0.035
0.111TrpCys: 0.111 ± 0.012
0.485TrpAsp: 0.485 ± 0.028
0.579TrpGlu: 0.579 ± 0.027
0.595TrpPhe: 0.595 ± 0.03
0.672TrpGly: 0.672 ± 0.034
0.437TrpHis: 0.437 ± 0.025
1.088TrpIle: 1.088 ± 0.043
0.638TrpLys: 0.638 ± 0.03
2.013TrpLeu: 2.013 ± 0.058
0.311TrpMet: 0.311 ± 0.02
0.359TrpAsn: 0.359 ± 0.023
0.218TrpPro: 0.218 ± 0.017
1.256TrpGln: 1.256 ± 0.048
0.894TrpArg: 0.894 ± 0.037
0.595TrpSer: 0.595 ± 0.032
0.51TrpThr: 0.51 ± 0.029
0.82TrpVal: 0.82 ± 0.036
0.226TrpTrp: 0.226 ± 0.021
0.375TrpTyr: 0.375 ± 0.027
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.87TyrAla: 2.87 ± 0.076
0.439TyrCys: 0.439 ± 0.024
1.762TyrAsp: 1.762 ± 0.053
1.472TyrGlu: 1.472 ± 0.048
1.5TyrPhe: 1.5 ± 0.05
2.421TyrGly: 2.421 ± 0.065
1.001TyrHis: 1.001 ± 0.036
1.767TyrIle: 1.767 ± 0.052
1.288TyrLys: 1.288 ± 0.048
4.045TyrLeu: 4.045 ± 0.078
0.537TyrMet: 0.537 ± 0.026
1.112TyrAsn: 1.112 ± 0.042
1.741TyrPro: 1.741 ± 0.053
2.559TyrGln: 2.559 ± 0.074
2.012TyrArg: 2.012 ± 0.054
2.105TyrSer: 2.105 ± 0.055
1.596TyrThr: 1.596 ± 0.049
1.524TyrVal: 1.524 ± 0.05
0.502TyrTrp: 0.502 ± 0.029
1.294TyrTyr: 1.294 ± 0.044
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2483 proteins (711237 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski