Amino acid dipepetide frequency for Apis mellifera associated microvirus 17

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.915AlaAla: 9.915 ± 2.781
0.0AlaCys: 0.0 ± 0.0
4.958AlaAsp: 4.958 ± 1.344
2.125AlaGlu: 2.125 ± 1.413
4.249AlaPhe: 4.249 ± 2.001
5.666AlaGly: 5.666 ± 1.999
2.125AlaHis: 2.125 ± 1.271
3.541AlaIle: 3.541 ± 2.76
6.374AlaLys: 6.374 ± 3.07
5.666AlaLeu: 5.666 ± 2.479
0.0AlaMet: 0.0 ± 0.0
6.374AlaAsn: 6.374 ± 1.423
4.249AlaPro: 4.249 ± 2.966
7.082AlaGln: 7.082 ± 1.909
7.79AlaArg: 7.79 ± 1.601
4.249AlaSer: 4.249 ± 1.721
6.374AlaThr: 6.374 ± 2.351
5.666AlaVal: 5.666 ± 2.657
0.708AlaTrp: 0.708 ± 0.615
2.125AlaTyr: 2.125 ± 0.578
0.0AlaXaa: 0.0 ± 0.0
Cys
1.416CysAla: 1.416 ± 0.583
0.0CysCys: 0.0 ± 0.0
0.708CysAsp: 0.708 ± 0.711
0.708CysGlu: 0.708 ± 0.615
1.416CysPhe: 1.416 ± 1.23
1.416CysGly: 1.416 ± 1.23
0.0CysHis: 0.0 ± 0.0
0.708CysIle: 0.708 ± 0.615
0.708CysLys: 0.708 ± 0.474
2.125CysLeu: 2.125 ± 0.872
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.708CysArg: 0.708 ± 0.615
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
1.416CysVal: 1.416 ± 1.408
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.958AspAla: 4.958 ± 1.509
0.0AspCys: 0.0 ± 0.0
2.833AspAsp: 2.833 ± 1.223
3.541AspGlu: 3.541 ± 1.321
6.374AspPhe: 6.374 ± 1.205
1.416AspGly: 1.416 ± 0.947
0.708AspHis: 0.708 ± 0.474
1.416AspIle: 1.416 ± 1.422
0.708AspLys: 0.708 ± 0.615
3.541AspLeu: 3.541 ± 1.413
0.0AspMet: 0.0 ± 0.0
1.416AspAsn: 1.416 ± 0.583
2.833AspPro: 2.833 ± 2.075
2.833AspGln: 2.833 ± 0.949
3.541AspArg: 3.541 ± 1.549
4.958AspSer: 4.958 ± 1.497
3.541AspThr: 3.541 ± 1.366
2.125AspVal: 2.125 ± 0.867
0.0AspTrp: 0.0 ± 0.0
2.833AspTyr: 2.833 ± 1.269
0.0AspXaa: 0.0 ± 0.0
Glu
4.249GluAla: 4.249 ± 1.535
0.708GluCys: 0.708 ± 0.711
1.416GluAsp: 1.416 ± 0.758
2.125GluGlu: 2.125 ± 0.855
0.708GluPhe: 0.708 ± 0.909
2.833GluGly: 2.833 ± 1.56
2.125GluHis: 2.125 ± 0.698
6.374GluIle: 6.374 ± 3.171
2.833GluLys: 2.833 ± 1.255
3.541GluLeu: 3.541 ± 1.647
0.708GluMet: 0.708 ± 0.715
2.125GluAsn: 2.125 ± 0.698
3.541GluPro: 3.541 ± 1.607
2.125GluGln: 2.125 ± 1.044
4.958GluArg: 4.958 ± 1.455
4.249GluSer: 4.249 ± 0.742
6.374GluThr: 6.374 ± 1.989
2.125GluVal: 2.125 ± 0.867
0.708GluTrp: 0.708 ± 0.474
2.833GluTyr: 2.833 ± 1.167
0.0GluXaa: 0.0 ± 0.0
Phe
2.833PheAla: 2.833 ± 0.861
0.708PheCys: 0.708 ± 0.909
4.249PheAsp: 4.249 ± 1.745
2.125PheGlu: 2.125 ± 1.257
2.125PhePhe: 2.125 ± 1.421
2.833PheGly: 2.833 ± 1.269
1.416PheHis: 1.416 ± 1.291
1.416PheIle: 1.416 ± 0.583
2.125PheLys: 2.125 ± 1.424
2.125PheLeu: 2.125 ± 1.421
3.541PheMet: 3.541 ± 1.139
2.833PheAsn: 2.833 ± 1.269
0.708PhePro: 0.708 ± 0.711
2.125PheGln: 2.125 ± 0.921
4.249PheArg: 4.249 ± 1.75
3.541PheSer: 3.541 ± 1.072
3.541PheThr: 3.541 ± 2.44
1.416PheVal: 1.416 ± 0.947
0.0PheTrp: 0.0 ± 0.0
1.416PheTyr: 1.416 ± 0.675
0.0PheXaa: 0.0 ± 0.0
Gly
6.374GlyAla: 6.374 ± 2.931
2.125GlyCys: 2.125 ± 1.101
8.499GlyAsp: 8.499 ± 1.648
5.666GlyGlu: 5.666 ± 1.332
2.833GlyPhe: 2.833 ± 1.167
7.082GlyGly: 7.082 ± 2.619
2.125GlyHis: 2.125 ± 0.867
4.249GlyIle: 4.249 ± 1.115
2.125GlyLys: 2.125 ± 0.872
4.249GlyLeu: 4.249 ± 1.365
1.416GlyMet: 1.416 ± 0.706
2.833GlyAsn: 2.833 ± 0.682
2.833GlyPro: 2.833 ± 0.88
2.125GlyGln: 2.125 ± 1.397
1.416GlyArg: 1.416 ± 0.825
2.833GlySer: 2.833 ± 0.682
5.666GlyThr: 5.666 ± 1.063
4.958GlyVal: 4.958 ± 1.978
0.708GlyTrp: 0.708 ± 1.104
2.833GlyTyr: 2.833 ± 1.269
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
1.416HisAsp: 1.416 ± 0.947
1.416HisGlu: 1.416 ± 0.825
2.833HisPhe: 2.833 ± 1.434
4.249HisGly: 4.249 ± 1.586
0.0HisHis: 0.0 ± 0.0
1.416HisIle: 1.416 ± 0.583
1.416HisLys: 1.416 ± 1.408
0.708HisLeu: 0.708 ± 0.474
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
2.125HisPro: 2.125 ± 1.915
0.708HisGln: 0.708 ± 0.715
0.708HisArg: 0.708 ± 0.615
2.833HisSer: 2.833 ± 1.816
1.416HisThr: 1.416 ± 1.073
1.416HisVal: 1.416 ± 0.947
0.0HisTrp: 0.0 ± 0.0
0.708HisTyr: 0.708 ± 0.615
0.0HisXaa: 0.0 ± 0.0
Ile
3.541IleAla: 3.541 ± 1.234
0.708IleCys: 0.708 ± 0.615
0.0IleAsp: 0.0 ± 0.0
1.416IleGlu: 1.416 ± 0.583
0.0IlePhe: 0.0 ± 0.0
5.666IleGly: 5.666 ± 0.985
0.708IleHis: 0.708 ± 0.615
2.125IleIle: 2.125 ± 0.921
0.708IleLys: 0.708 ± 0.909
2.833IleLeu: 2.833 ± 1.255
0.708IleMet: 0.708 ± 1.104
3.541IleAsn: 3.541 ± 1.366
3.541IlePro: 3.541 ± 1.726
2.125IleGln: 2.125 ± 0.872
2.833IleArg: 2.833 ± 1.274
3.541IleSer: 3.541 ± 1.437
4.249IleThr: 4.249 ± 1.75
2.833IleVal: 2.833 ± 1.283
0.708IleTrp: 0.708 ± 0.474
1.416IleTyr: 1.416 ± 0.947
0.0IleXaa: 0.0 ± 0.0
Lys
7.082LysAla: 7.082 ± 3.195
0.708LysCys: 0.708 ± 0.615
1.416LysAsp: 1.416 ± 1.422
1.416LysGlu: 1.416 ± 0.758
2.833LysPhe: 2.833 ± 1.075
3.541LysGly: 3.541 ± 1.107
0.0LysHis: 0.0 ± 0.0
2.125LysIle: 2.125 ± 1.601
5.666LysLys: 5.666 ± 2.91
6.374LysLeu: 6.374 ± 1.453
2.833LysMet: 2.833 ± 2.897
2.833LysAsn: 2.833 ± 1.582
3.541LysPro: 3.541 ± 1.249
1.416LysGln: 1.416 ± 0.971
3.541LysArg: 3.541 ± 1.838
2.833LysSer: 2.833 ± 0.983
4.958LysThr: 4.958 ± 1.533
0.708LysVal: 0.708 ± 0.474
0.0LysTrp: 0.0 ± 0.0
3.541LysTyr: 3.541 ± 2.045
0.0LysXaa: 0.0 ± 0.0
Leu
6.374LeuAla: 6.374 ± 2.015
0.0LeuCys: 0.0 ± 0.0
3.541LeuAsp: 3.541 ± 1.173
8.499LeuGlu: 8.499 ± 3.272
2.833LeuPhe: 2.833 ± 0.88
4.249LeuGly: 4.249 ± 1.29
2.125LeuHis: 2.125 ± 1.067
2.125LeuIle: 2.125 ± 1.238
1.416LeuLys: 1.416 ± 0.825
4.249LeuLeu: 4.249 ± 2.195
0.708LeuMet: 0.708 ± 1.104
4.958LeuAsn: 4.958 ± 1.815
7.79LeuPro: 7.79 ± 2.178
4.958LeuGln: 4.958 ± 1.8
8.499LeuArg: 8.499 ± 3.203
2.125LeuSer: 2.125 ± 0.578
5.666LeuThr: 5.666 ± 2.021
3.541LeuVal: 3.541 ± 1.863
1.416LeuTrp: 1.416 ± 1.23
1.416LeuTyr: 1.416 ± 0.583
0.0LeuXaa: 0.0 ± 0.0
Met
1.416MetAla: 1.416 ± 1.287
0.0MetCys: 0.0 ± 0.0
0.708MetAsp: 0.708 ± 0.474
0.708MetGlu: 0.708 ± 0.711
1.416MetPhe: 1.416 ± 0.808
2.125MetGly: 2.125 ± 1.308
0.708MetHis: 0.708 ± 0.909
0.708MetIle: 0.708 ± 0.715
3.541MetLys: 3.541 ± 1.773
1.416MetLeu: 1.416 ± 0.947
0.0MetMet: 0.0 ± 0.0
2.833MetAsn: 2.833 ± 1.434
1.416MetPro: 1.416 ± 0.583
1.416MetGln: 1.416 ± 1.218
0.708MetArg: 0.708 ± 1.104
0.708MetSer: 0.708 ± 1.104
0.0MetThr: 0.0 ± 0.0
2.125MetVal: 2.125 ± 1.308
0.708MetTrp: 0.708 ± 0.474
0.708MetTyr: 0.708 ± 0.474
0.0MetXaa: 0.0 ± 0.0
Asn
3.541AsnAla: 3.541 ± 1.863
0.708AsnCys: 0.708 ± 0.615
1.416AsnAsp: 1.416 ± 0.971
4.958AsnGlu: 4.958 ± 1.867
1.416AsnPhe: 1.416 ± 0.583
1.416AsnGly: 1.416 ± 0.675
0.708AsnHis: 0.708 ± 0.711
2.833AsnIle: 2.833 ± 1.283
3.541AsnLys: 3.541 ± 1.096
5.666AsnLeu: 5.666 ± 2.499
0.708AsnMet: 0.708 ± 0.474
2.125AsnAsn: 2.125 ± 0.855
5.666AsnPro: 5.666 ± 1.421
0.708AsnGln: 0.708 ± 0.715
2.833AsnArg: 2.833 ± 1.35
4.249AsnSer: 4.249 ± 1.074
0.708AsnThr: 0.708 ± 0.474
2.125AsnVal: 2.125 ± 0.921
0.0AsnTrp: 0.0 ± 0.0
0.708AsnTyr: 0.708 ± 0.474
0.0AsnXaa: 0.0 ± 0.0
Pro
5.666ProAla: 5.666 ± 2.672
1.416ProCys: 1.416 ± 1.23
3.541ProAsp: 3.541 ± 1.202
2.125ProGlu: 2.125 ± 0.867
2.833ProPhe: 2.833 ± 1.225
6.374ProGly: 6.374 ± 2.125
2.125ProHis: 2.125 ± 0.867
1.416ProIle: 1.416 ± 0.808
4.249ProLys: 4.249 ± 2.763
3.541ProLeu: 3.541 ± 2.05
2.833ProMet: 2.833 ± 1.318
0.708ProAsn: 0.708 ± 0.474
3.541ProPro: 3.541 ± 1.492
2.833ProGln: 2.833 ± 1.894
2.833ProArg: 2.833 ± 1.283
3.541ProSer: 3.541 ± 1.22
4.958ProThr: 4.958 ± 2.244
8.499ProVal: 8.499 ± 1.782
1.416ProTrp: 1.416 ± 0.583
2.125ProTyr: 2.125 ± 1.067
0.0ProXaa: 0.0 ± 0.0
Gln
3.541GlnAla: 3.541 ± 0.617
1.416GlnCys: 1.416 ± 1.211
2.125GlnAsp: 2.125 ± 0.855
2.833GlnGlu: 2.833 ± 1.3
0.0GlnPhe: 0.0 ± 0.0
2.833GlnGly: 2.833 ± 1.3
0.708GlnHis: 0.708 ± 0.909
2.125GlnIle: 2.125 ± 1.238
4.958GlnLys: 4.958 ± 1.978
3.541GlnLeu: 3.541 ± 2.051
2.125GlnMet: 2.125 ± 1.308
4.958GlnAsn: 4.958 ± 1.978
0.0GlnPro: 0.0 ± 0.0
0.708GlnGln: 0.708 ± 0.474
4.249GlnArg: 4.249 ± 1.627
0.708GlnSer: 0.708 ± 0.909
1.416GlnThr: 1.416 ± 0.808
1.416GlnVal: 1.416 ± 0.675
0.708GlnTrp: 0.708 ± 0.615
0.708GlnTyr: 0.708 ± 0.715
0.0GlnXaa: 0.0 ± 0.0
Arg
7.082ArgAla: 7.082 ± 1.966
0.708ArgCys: 0.708 ± 0.615
4.958ArgAsp: 4.958 ± 1.888
2.125ArgGlu: 2.125 ± 1.397
0.708ArgPhe: 0.708 ± 0.711
3.541ArgGly: 3.541 ± 0.915
1.416ArgHis: 1.416 ± 0.808
0.708ArgIle: 0.708 ± 0.711
6.374ArgLys: 6.374 ± 3.0
4.958ArgLeu: 4.958 ± 1.578
2.125ArgMet: 2.125 ± 0.837
1.416ArgAsn: 1.416 ± 0.808
7.082ArgPro: 7.082 ± 2.958
2.125ArgGln: 2.125 ± 0.578
6.374ArgArg: 6.374 ± 1.083
5.666ArgSer: 5.666 ± 2.243
3.541ArgThr: 3.541 ± 1.249
4.958ArgVal: 4.958 ± 0.969
0.0ArgTrp: 0.0 ± 0.0
2.833ArgTyr: 2.833 ± 1.269
0.0ArgXaa: 0.0 ± 0.0
Ser
7.082SerAla: 7.082 ± 3.732
0.708SerCys: 0.708 ± 0.474
0.708SerAsp: 0.708 ± 0.711
4.958SerGlu: 4.958 ± 1.25
2.833SerPhe: 2.833 ± 1.269
3.541SerGly: 3.541 ± 1.647
2.833SerHis: 2.833 ± 1.269
3.541SerIle: 3.541 ± 2.286
4.249SerLys: 4.249 ± 0.794
7.79SerLeu: 7.79 ± 2.922
2.125SerMet: 2.125 ± 0.855
0.708SerAsn: 0.708 ± 0.474
3.541SerPro: 3.541 ± 0.617
1.416SerGln: 1.416 ± 1.189
2.833SerArg: 2.833 ± 0.984
7.082SerSer: 7.082 ± 2.928
4.958SerThr: 4.958 ± 1.872
2.125SerVal: 2.125 ± 0.867
0.0SerTrp: 0.0 ± 0.0
1.416SerTyr: 1.416 ± 0.583
0.0SerXaa: 0.0 ± 0.0
Thr
4.958ThrAla: 4.958 ± 1.677
1.416ThrCys: 1.416 ± 0.808
2.125ThrAsp: 2.125 ± 0.578
5.666ThrGlu: 5.666 ± 1.984
3.541ThrPhe: 3.541 ± 1.022
7.79ThrGly: 7.79 ± 1.604
1.416ThrHis: 1.416 ± 0.583
4.249ThrIle: 4.249 ± 1.733
3.541ThrLys: 3.541 ± 0.915
5.666ThrLeu: 5.666 ± 1.845
1.416ThrMet: 1.416 ± 1.22
1.416ThrAsn: 1.416 ± 0.947
5.666ThrPro: 5.666 ± 2.796
2.833ThrGln: 2.833 ± 1.382
3.541ThrArg: 3.541 ± 2.246
3.541ThrSer: 3.541 ± 1.399
3.541ThrThr: 3.541 ± 1.726
2.125ThrVal: 2.125 ± 1.067
0.708ThrTrp: 0.708 ± 0.474
0.708ThrTyr: 0.708 ± 0.615
0.0ThrXaa: 0.0 ± 0.0
Val
5.666ValAla: 5.666 ± 1.333
0.0ValCys: 0.0 ± 0.0
3.541ValAsp: 3.541 ± 1.022
1.416ValGlu: 1.416 ± 0.758
4.249ValPhe: 4.249 ± 1.073
2.125ValGly: 2.125 ± 1.308
0.0ValHis: 0.0 ± 0.0
2.125ValIle: 2.125 ± 1.238
1.416ValLys: 1.416 ± 1.23
4.958ValLeu: 4.958 ± 1.939
0.708ValMet: 0.708 ± 0.474
2.833ValAsn: 2.833 ± 1.013
4.958ValPro: 4.958 ± 2.747
1.416ValGln: 1.416 ± 0.825
3.541ValArg: 3.541 ± 1.526
5.666ValSer: 5.666 ± 1.329
4.249ValThr: 4.249 ± 1.721
2.833ValVal: 2.833 ± 1.577
1.416ValTrp: 1.416 ± 0.947
2.833ValTyr: 2.833 ± 0.949
0.0ValXaa: 0.0 ± 0.0
Trp
0.708TrpAla: 0.708 ± 0.615
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.708TrpPhe: 0.708 ± 0.474
0.708TrpGly: 0.708 ± 0.615
0.708TrpHis: 0.708 ± 0.474
0.0TrpIle: 0.0 ± 0.0
0.708TrpLys: 0.708 ± 0.615
0.708TrpLeu: 0.708 ± 0.615
0.0TrpMet: 0.0 ± 0.0
1.416TrpAsn: 1.416 ± 0.947
2.833TrpPro: 2.833 ± 1.121
0.708TrpGln: 0.708 ± 0.474
0.0TrpArg: 0.0 ± 0.0
0.708TrpSer: 0.708 ± 0.474
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.833TyrAla: 2.833 ± 0.682
0.0TyrCys: 0.0 ± 0.0
1.416TyrAsp: 1.416 ± 0.808
2.833TyrGlu: 2.833 ± 1.685
1.416TyrPhe: 1.416 ± 0.947
3.541TyrGly: 3.541 ± 1.651
1.416TyrHis: 1.416 ± 1.094
0.0TyrIle: 0.0 ± 0.0
0.708TyrLys: 0.708 ± 0.474
2.833TyrLeu: 2.833 ± 1.269
0.708TyrMet: 0.708 ± 0.474
0.708TyrAsn: 0.708 ± 0.474
1.416TyrPro: 1.416 ± 1.094
1.416TyrGln: 1.416 ± 0.947
3.541TyrArg: 3.541 ± 1.022
1.416TyrSer: 1.416 ± 0.825
0.708TyrThr: 0.708 ± 0.474
3.541TyrVal: 3.541 ± 1.249
0.708TyrTrp: 0.708 ± 0.474
1.416TyrTyr: 1.416 ± 1.23
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1413 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski