Amino acid dipepetide frequency for Changping Tick Virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.461AlaAla: 6.461 ± 8.3
2.661AlaCys: 2.661 ± 0.17
3.041AlaAsp: 3.041 ± 0.359
5.321AlaGlu: 5.321 ± 0.341
4.181AlaPhe: 4.181 ± 1.376
2.661AlaGly: 2.661 ± 2.131
0.0AlaHis: 0.0 ± 0.0
2.661AlaIle: 2.661 ± 0.17
4.561AlaLys: 4.561 ± 0.037
6.461AlaLeu: 6.461 ± 2.546
1.9AlaMet: 1.9 ± 0.944
3.041AlaAsn: 3.041 ± 0.359
3.041AlaPro: 3.041 ± 3.094
3.421AlaGln: 3.421 ± 0.603
6.461AlaArg: 6.461 ± 3.697
5.321AlaSer: 5.321 ± 0.81
3.421AlaThr: 3.421 ± 2.905
5.701AlaVal: 5.701 ± 2.923
0.76AlaTrp: 0.76 ± 0.378
5.321AlaTyr: 5.321 ± 0.341
0.0AlaXaa: 0.0 ± 0.0
Cys
1.9CysAla: 1.9 ± 0.207
0.0CysCys: 0.0 ± 0.0
1.52CysAsp: 1.52 ± 0.755
0.38CysGlu: 0.38 ± 0.189
0.38CysPhe: 0.38 ± 0.189
0.0CysGly: 0.0 ± 0.0
0.76CysHis: 0.76 ± 0.378
1.14CysIle: 1.14 ± 0.566
0.38CysLys: 0.38 ± 0.962
2.661CysLeu: 2.661 ± 1.321
0.76CysMet: 0.76 ± 0.378
0.0CysAsn: 0.0 ± 0.0
1.9CysPro: 1.9 ± 0.944
0.76CysGln: 0.76 ± 0.378
1.9CysArg: 1.9 ± 0.944
0.38CysSer: 0.38 ± 0.189
1.14CysThr: 1.14 ± 0.566
0.38CysVal: 0.38 ± 0.189
0.38CysTrp: 0.38 ± 0.189
2.281CysTyr: 2.281 ± 0.018
0.0CysXaa: 0.0 ± 0.0
Asp
3.801AspAla: 3.801 ± 0.414
0.38AspCys: 0.38 ± 0.189
2.661AspAsp: 2.661 ± 0.17
3.041AspGlu: 3.041 ± 0.792
2.281AspPhe: 2.281 ± 0.018
2.281AspGly: 2.281 ± 0.018
1.14AspHis: 1.14 ± 0.585
4.561AspIle: 4.561 ± 1.114
1.9AspLys: 1.9 ± 0.207
6.081AspLeu: 6.081 ± 0.718
0.76AspMet: 0.76 ± 0.378
0.38AspAsn: 0.38 ± 0.189
3.041AspPro: 3.041 ± 1.51
0.38AspGln: 0.38 ± 0.962
3.801AspArg: 3.801 ± 1.888
3.421AspSer: 3.421 ± 0.603
3.041AspThr: 3.041 ± 1.943
4.561AspVal: 4.561 ± 0.037
1.14AspTrp: 1.14 ± 0.566
2.661AspTyr: 2.661 ± 1.321
0.0AspXaa: 0.0 ± 0.0
Glu
4.561GluAla: 4.561 ± 1.188
0.76GluCys: 0.76 ± 0.378
3.041GluAsp: 3.041 ± 1.51
5.321GluGlu: 5.321 ± 0.341
2.661GluPhe: 2.661 ± 0.17
4.941GluGly: 4.941 ± 1.303
3.041GluHis: 3.041 ± 1.943
2.281GluIle: 2.281 ± 1.133
3.421GluLys: 3.421 ± 0.548
8.362GluLeu: 8.362 ± 5.055
1.14GluMet: 1.14 ± 0.566
2.281GluAsn: 2.281 ± 1.133
1.52GluPro: 1.52 ± 0.755
3.041GluGln: 3.041 ± 1.51
3.041GluArg: 3.041 ± 1.51
4.181GluSer: 4.181 ± 0.925
1.9GluThr: 1.9 ± 0.944
4.181GluVal: 4.181 ± 0.226
1.9GluTrp: 1.9 ± 0.944
3.041GluTyr: 3.041 ± 0.359
0.0GluXaa: 0.0 ± 0.0
Phe
3.421PheAla: 3.421 ± 0.603
1.14PheCys: 1.14 ± 0.566
3.421PheAsp: 3.421 ± 0.548
1.52PheGlu: 1.52 ± 0.755
1.9PhePhe: 1.9 ± 0.207
1.14PheGly: 1.14 ± 0.566
0.0PheHis: 0.0 ± 0.0
1.9PheIle: 1.9 ± 0.207
1.9PheLys: 1.9 ± 0.944
4.181PheLeu: 4.181 ± 1.376
0.38PheMet: 0.38 ± 0.189
1.14PheAsn: 1.14 ± 0.566
2.281PhePro: 2.281 ± 2.32
1.52PheGln: 1.52 ± 2.698
3.421PheArg: 3.421 ± 0.603
1.9PheSer: 1.9 ± 0.944
1.52PheThr: 1.52 ± 0.755
4.181PheVal: 4.181 ± 0.925
0.76PheTrp: 0.76 ± 0.378
1.9PheTyr: 1.9 ± 0.944
0.0PheXaa: 0.0 ± 0.0
Gly
2.661GlyAla: 2.661 ± 0.981
1.52GlyCys: 1.52 ± 0.755
3.801GlyAsp: 3.801 ± 0.414
4.561GlyGlu: 4.561 ± 1.114
2.661GlyPhe: 2.661 ± 0.981
1.9GlyGly: 1.9 ± 0.207
1.52GlyHis: 1.52 ± 0.396
2.281GlyIle: 2.281 ± 0.018
3.041GlyLys: 3.041 ± 0.359
4.941GlyLeu: 4.941 ± 0.999
1.14GlyMet: 1.14 ± 0.566
1.52GlyAsn: 1.52 ± 0.755
1.52GlyPro: 1.52 ± 1.547
1.14GlyGln: 1.14 ± 1.736
3.801GlyArg: 3.801 ± 0.737
2.661GlySer: 2.661 ± 0.981
3.421GlyThr: 3.421 ± 4.056
2.661GlyVal: 2.661 ± 0.17
0.76GlyTrp: 0.76 ± 0.773
2.281GlyTyr: 2.281 ± 1.133
0.38GlyXaa: 0.38 ± 0.189
His
1.52HisAla: 1.52 ± 2.698
0.38HisCys: 0.38 ± 0.189
0.38HisAsp: 0.38 ± 0.189
2.661HisGlu: 2.661 ± 1.321
0.76HisPhe: 0.76 ± 0.378
0.38HisGly: 0.38 ± 0.189
0.76HisHis: 0.76 ± 0.378
1.52HisIle: 1.52 ± 0.396
1.9HisLys: 1.9 ± 0.207
4.181HisLeu: 4.181 ± 1.376
0.38HisMet: 0.38 ± 0.189
1.52HisAsn: 1.52 ± 0.396
1.9HisPro: 1.9 ± 0.944
1.14HisGln: 1.14 ± 0.566
1.9HisArg: 1.9 ± 0.207
1.9HisSer: 1.9 ± 0.944
0.0HisThr: 0.0 ± 0.0
2.281HisVal: 2.281 ± 1.133
1.14HisTrp: 1.14 ± 0.585
1.52HisTyr: 1.52 ± 0.755
0.0HisXaa: 0.0 ± 0.0
Ile
3.421IleAla: 3.421 ± 0.548
0.38IleCys: 0.38 ± 0.189
1.52IleAsp: 1.52 ± 0.755
3.041IleGlu: 3.041 ± 1.51
0.76IlePhe: 0.76 ± 0.378
3.041IleGly: 3.041 ± 0.359
0.76IleHis: 0.76 ± 0.378
1.52IleIle: 1.52 ± 0.755
2.661IleLys: 2.661 ± 0.981
3.421IleLeu: 3.421 ± 1.699
1.9IleMet: 1.9 ± 0.207
3.801IleAsn: 3.801 ± 1.888
3.041IlePro: 3.041 ± 1.51
2.281IleGln: 2.281 ± 1.169
4.181IleArg: 4.181 ± 0.925
4.561IleSer: 4.561 ± 0.037
5.321IleThr: 5.321 ± 0.81
1.9IleVal: 1.9 ± 0.944
0.38IleTrp: 0.38 ± 0.189
2.281IleTyr: 2.281 ± 1.133
0.0IleXaa: 0.0 ± 0.0
Lys
4.181LysAla: 4.181 ± 0.226
0.76LysCys: 0.76 ± 0.378
3.041LysAsp: 3.041 ± 1.51
4.941LysGlu: 4.941 ± 0.152
3.801LysPhe: 3.801 ± 0.737
0.38LysGly: 0.38 ± 0.962
1.14LysHis: 1.14 ± 0.585
3.041LysIle: 3.041 ± 0.792
2.661LysLys: 2.661 ± 0.17
4.181LysLeu: 4.181 ± 0.925
1.14LysMet: 1.14 ± 0.566
2.281LysAsn: 2.281 ± 1.133
1.52LysPro: 1.52 ± 0.755
1.9LysGln: 1.9 ± 0.944
2.661LysArg: 2.661 ± 0.981
1.52LysSer: 1.52 ± 0.755
5.321LysThr: 5.321 ± 0.341
4.181LysVal: 4.181 ± 2.076
0.38LysTrp: 0.38 ± 0.189
1.14LysTyr: 1.14 ± 0.566
0.0LysXaa: 0.0 ± 0.0
Leu
6.081LeuAla: 6.081 ± 3.885
1.52LeuCys: 1.52 ± 1.547
6.842LeuAsp: 6.842 ± 2.357
6.842LeuGlu: 6.842 ± 1.206
3.421LeuPhe: 3.421 ± 1.754
6.461LeuGly: 6.461 ± 0.907
3.421LeuHis: 3.421 ± 0.548
3.421LeuIle: 3.421 ± 1.699
4.561LeuLys: 4.561 ± 1.114
11.022LeuLeu: 11.022 ± 1.432
2.281LeuMet: 2.281 ± 0.018
3.421LeuAsn: 3.421 ± 0.603
6.461LeuPro: 6.461 ± 0.244
6.081LeuGln: 6.081 ± 0.718
7.982LeuArg: 7.982 ± 0.64
9.122LeuSer: 9.122 ± 0.073
5.321LeuThr: 5.321 ± 1.961
7.982LeuVal: 7.982 ± 1.791
2.661LeuTrp: 2.661 ± 1.321
2.661LeuTyr: 2.661 ± 0.17
0.0LeuXaa: 0.0 ± 0.0
Met
2.281MetAla: 2.281 ± 2.32
0.38MetCys: 0.38 ± 0.189
0.38MetAsp: 0.38 ± 0.189
2.281MetGlu: 2.281 ± 1.133
0.0MetPhe: 0.0 ± 0.0
1.52MetGly: 1.52 ± 0.755
0.76MetHis: 0.76 ± 0.378
1.14MetIle: 1.14 ± 0.566
1.14MetLys: 1.14 ± 0.585
1.9MetLeu: 1.9 ± 0.944
0.76MetMet: 0.76 ± 0.378
0.38MetAsn: 0.38 ± 0.189
1.52MetPro: 1.52 ± 0.755
0.0MetGln: 0.0 ± 0.0
1.52MetArg: 1.52 ± 0.755
1.9MetSer: 1.9 ± 0.944
2.281MetThr: 2.281 ± 0.018
2.661MetVal: 2.661 ± 0.981
0.0MetTrp: 0.0 ± 0.0
0.76MetTyr: 0.76 ± 0.378
0.0MetXaa: 0.0 ± 0.0
Asn
3.801AsnAla: 3.801 ± 2.716
0.38AsnCys: 0.38 ± 0.189
1.9AsnAsp: 1.9 ± 0.207
1.9AsnGlu: 1.9 ± 0.207
2.281AsnPhe: 2.281 ± 0.018
1.52AsnGly: 1.52 ± 0.396
0.76AsnHis: 0.76 ± 0.378
3.421AsnIle: 3.421 ± 1.699
1.14AsnLys: 1.14 ± 0.566
3.041AsnLeu: 3.041 ± 1.943
1.9AsnMet: 1.9 ± 0.944
1.52AsnAsn: 1.52 ± 1.547
0.76AsnPro: 0.76 ± 0.773
1.9AsnGln: 1.9 ± 0.207
1.14AsnArg: 1.14 ± 0.585
1.52AsnSer: 1.52 ± 0.755
1.14AsnThr: 1.14 ± 0.566
1.9AsnVal: 1.9 ± 0.944
0.0AsnTrp: 0.0 ± 0.0
0.76AsnTyr: 0.76 ± 0.378
0.0AsnXaa: 0.0 ± 0.0
Pro
2.661ProAla: 2.661 ± 0.17
0.76ProCys: 0.76 ± 0.378
5.321ProAsp: 5.321 ± 1.492
4.181ProGlu: 4.181 ± 1.376
2.661ProPhe: 2.661 ± 1.321
2.661ProGly: 2.661 ± 0.981
2.281ProHis: 2.281 ± 0.018
1.14ProIle: 1.14 ± 0.566
1.9ProLys: 1.9 ± 0.944
3.041ProLeu: 3.041 ± 0.359
0.76ProMet: 0.76 ± 0.378
1.52ProAsn: 1.52 ± 1.547
2.661ProPro: 2.661 ± 0.17
1.14ProGln: 1.14 ± 0.585
3.421ProArg: 3.421 ± 0.603
1.9ProSer: 1.9 ± 0.944
1.52ProThr: 1.52 ± 0.396
3.421ProVal: 3.421 ± 0.548
1.9ProTrp: 1.9 ± 0.207
3.801ProTyr: 3.801 ± 1.888
0.0ProXaa: 0.0 ± 0.0
Gln
3.801GlnAla: 3.801 ± 2.716
0.38GlnCys: 0.38 ± 0.189
0.76GlnAsp: 0.76 ± 0.378
2.281GlnGlu: 2.281 ± 0.018
0.0GlnPhe: 0.0 ± 0.0
3.041GlnGly: 3.041 ± 0.359
1.52GlnHis: 1.52 ± 0.755
1.52GlnIle: 1.52 ± 0.755
2.281GlnLys: 2.281 ± 1.133
6.081GlnLeu: 6.081 ± 1.869
0.38GlnMet: 0.38 ± 0.962
0.76GlnAsn: 0.76 ± 1.924
1.9GlnPro: 1.9 ± 0.207
2.281GlnGln: 2.281 ± 3.471
2.281GlnArg: 2.281 ± 0.018
2.281GlnSer: 2.281 ± 0.018
2.661GlnThr: 2.661 ± 0.17
3.801GlnVal: 3.801 ± 0.737
0.76GlnTrp: 0.76 ± 0.378
1.9GlnTyr: 1.9 ± 0.207
0.0GlnXaa: 0.0 ± 0.0
Arg
5.321ArgAla: 5.321 ± 1.961
1.9ArgCys: 1.9 ± 0.944
1.9ArgAsp: 1.9 ± 0.944
5.701ArgGlu: 5.701 ± 0.53
1.9ArgPhe: 1.9 ± 0.944
4.181ArgGly: 4.181 ± 1.376
2.281ArgHis: 2.281 ± 0.018
2.281ArgIle: 2.281 ± 1.133
3.801ArgLys: 3.801 ± 1.888
7.982ArgLeu: 7.982 ± 0.511
1.52ArgMet: 1.52 ± 1.547
1.52ArgAsn: 1.52 ± 2.698
2.281ArgPro: 2.281 ± 1.133
1.9ArgGln: 1.9 ± 0.944
4.181ArgArg: 4.181 ± 0.226
4.941ArgSer: 4.941 ± 0.999
3.801ArgThr: 3.801 ± 0.414
4.941ArgVal: 4.941 ± 2.15
1.9ArgTrp: 1.9 ± 0.944
2.281ArgTyr: 2.281 ± 1.169
0.0ArgXaa: 0.0 ± 0.0
Ser
4.941SerAla: 4.941 ± 1.303
2.661SerCys: 2.661 ± 1.321
3.041SerAsp: 3.041 ± 0.792
1.9SerGlu: 1.9 ± 0.944
2.661SerPhe: 2.661 ± 1.321
1.9SerGly: 1.9 ± 0.207
3.041SerHis: 3.041 ± 0.359
4.181SerIle: 4.181 ± 0.925
4.561SerLys: 4.561 ± 1.114
7.982SerLeu: 7.982 ± 0.64
1.9SerMet: 1.9 ± 0.706
1.14SerAsn: 1.14 ± 0.566
1.9SerPro: 1.9 ± 0.944
3.041SerGln: 3.041 ± 1.51
3.801SerArg: 3.801 ± 0.414
4.181SerSer: 4.181 ± 0.925
2.281SerThr: 2.281 ± 1.133
3.421SerVal: 3.421 ± 0.548
1.14SerTrp: 1.14 ± 0.585
3.041SerTyr: 3.041 ± 1.943
0.0SerXaa: 0.0 ± 0.0
Thr
3.801ThrAla: 3.801 ± 1.565
0.0ThrCys: 0.0 ± 0.0
3.041ThrAsp: 3.041 ± 0.792
2.281ThrGlu: 2.281 ± 1.169
2.661ThrPhe: 2.661 ± 2.131
3.041ThrGly: 3.041 ± 0.792
3.041ThrHis: 3.041 ± 1.51
4.561ThrIle: 4.561 ± 2.339
2.281ThrLys: 2.281 ± 1.133
6.461ThrLeu: 6.461 ± 3.697
1.14ThrMet: 1.14 ± 0.566
1.14ThrAsn: 1.14 ± 0.566
3.421ThrPro: 3.421 ± 0.548
3.041ThrGln: 3.041 ± 1.51
2.281ThrArg: 2.281 ± 0.018
2.281ThrSer: 2.281 ± 0.018
5.321ThrThr: 5.321 ± 0.341
2.661ThrVal: 2.661 ± 0.17
1.14ThrTrp: 1.14 ± 0.585
2.661ThrTyr: 2.661 ± 0.17
0.0ThrXaa: 0.0 ± 0.0
Val
7.222ValAla: 7.222 ± 0.134
1.9ValCys: 1.9 ± 0.944
1.9ValAsp: 1.9 ± 2.509
4.181ValGlu: 4.181 ± 0.925
2.281ValPhe: 2.281 ± 0.018
4.181ValGly: 4.181 ± 3.678
1.14ValHis: 1.14 ± 0.585
4.181ValIle: 4.181 ± 0.925
2.281ValLys: 2.281 ± 0.018
9.502ValLeu: 9.502 ± 1.266
1.9ValMet: 1.9 ± 0.865
2.281ValAsn: 2.281 ± 0.018
5.701ValPro: 5.701 ± 0.53
2.661ValGln: 2.661 ± 1.321
4.181ValArg: 4.181 ± 0.226
5.321ValSer: 5.321 ± 1.492
2.281ValThr: 2.281 ± 1.169
5.321ValVal: 5.321 ± 0.81
0.38ValTrp: 0.38 ± 0.189
1.9ValTyr: 1.9 ± 0.944
0.0ValXaa: 0.0 ± 0.0
Trp
1.14TrpAla: 1.14 ± 0.566
0.38TrpCys: 0.38 ± 0.189
1.14TrpAsp: 1.14 ± 0.566
1.14TrpGlu: 1.14 ± 0.566
0.38TrpPhe: 0.38 ± 0.189
1.14TrpGly: 1.14 ± 0.585
0.0TrpHis: 0.0 ± 0.0
0.76TrpIle: 0.76 ± 0.378
1.52TrpLys: 1.52 ± 0.755
0.76TrpLeu: 0.76 ± 0.773
1.14TrpMet: 1.14 ± 0.566
1.14TrpAsn: 1.14 ± 0.585
1.52TrpPro: 1.52 ± 0.755
0.38TrpGln: 0.38 ± 0.189
2.281TrpArg: 2.281 ± 0.018
0.38TrpSer: 0.38 ± 0.189
0.76TrpThr: 0.76 ± 0.378
1.52TrpVal: 1.52 ± 0.396
0.38TrpTrp: 0.38 ± 0.189
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.421TyrAla: 3.421 ± 1.699
0.76TyrCys: 0.76 ± 0.378
2.281TyrAsp: 2.281 ± 0.018
1.14TyrGlu: 1.14 ± 0.566
1.9TyrPhe: 1.9 ± 0.944
3.801TyrGly: 3.801 ± 0.414
0.76TyrHis: 0.76 ± 0.378
2.661TyrIle: 2.661 ± 1.321
2.281TyrLys: 2.281 ± 0.018
5.321TyrLeu: 5.321 ± 0.81
0.0TyrMet: 0.0 ± 0.0
1.9TyrAsn: 1.9 ± 0.207
0.76TyrPro: 0.76 ± 0.378
2.661TyrGln: 2.661 ± 0.981
2.281TyrArg: 2.281 ± 1.169
3.421TyrSer: 3.421 ± 1.699
3.801TyrThr: 3.801 ± 1.888
3.041TyrVal: 3.041 ± 1.51
0.0TyrTrp: 0.0 ± 0.0
0.76TyrTyr: 0.76 ± 0.773
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.38XaaAsp: 0.38 ± 0.189
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2632 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski