Amino acid dipepetide frequency for Photobacterium angustum (strain S14 / CCUG 15956) (Vibrio sp. (strain S14 / CCUG 15956))

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.213AlaAla: 7.213 ± 0.106
0.948AlaCys: 0.948 ± 0.03
4.461AlaAsp: 4.461 ± 0.065
5.1AlaGlu: 5.1 ± 0.073
3.316AlaPhe: 3.316 ± 0.052
5.537AlaGly: 5.537 ± 0.082
1.552AlaHis: 1.552 ± 0.03
6.281AlaIle: 6.281 ± 0.075
4.933AlaLys: 4.933 ± 0.067
9.265AlaLeu: 9.265 ± 0.101
2.66AlaMet: 2.66 ± 0.061
3.618AlaAsn: 3.618 ± 0.059
2.768AlaPro: 2.768 ± 0.05
3.516AlaGln: 3.516 ± 0.054
3.177AlaArg: 3.177 ± 0.053
5.099AlaSer: 5.099 ± 0.059
4.607AlaThr: 4.607 ± 0.061
5.647AlaVal: 5.647 ± 0.068
0.906AlaTrp: 0.906 ± 0.025
2.303AlaTyr: 2.303 ± 0.039
0.0AlaXaa: 0.0 ± 0.0
Cys
0.783CysAla: 0.783 ± 0.027
0.196CysCys: 0.196 ± 0.014
0.701CysAsp: 0.701 ± 0.024
0.642CysGlu: 0.642 ± 0.024
0.52CysPhe: 0.52 ± 0.018
0.954CysGly: 0.954 ± 0.028
0.388CysHis: 0.388 ± 0.019
0.678CysIle: 0.678 ± 0.025
0.494CysLys: 0.494 ± 0.018
1.049CysLeu: 1.049 ± 0.028
0.252CysMet: 0.252 ± 0.014
0.47CysAsn: 0.47 ± 0.019
0.447CysPro: 0.447 ± 0.02
0.497CysGln: 0.497 ± 0.017
0.518CysArg: 0.518 ± 0.02
0.777CysSer: 0.777 ± 0.023
0.478CysThr: 0.478 ± 0.017
0.689CysVal: 0.689 ± 0.023
0.143CysTrp: 0.143 ± 0.009
0.408CysTyr: 0.408 ± 0.017
0.0CysXaa: 0.0 ± 0.0
Asp
4.262AspAla: 4.262 ± 0.069
0.578AspCys: 0.578 ± 0.022
3.289AspAsp: 3.289 ± 0.067
3.563AspGlu: 3.563 ± 0.058
2.415AspPhe: 2.415 ± 0.044
3.894AspGly: 3.894 ± 0.128
1.247AspHis: 1.247 ± 0.036
4.382AspIle: 4.382 ± 0.065
3.511AspLys: 3.511 ± 0.048
5.208AspLeu: 5.208 ± 0.073
1.415AspMet: 1.415 ± 0.031
2.964AspAsn: 2.964 ± 0.064
2.079AspPro: 2.079 ± 0.043
1.974AspGln: 1.974 ± 0.041
2.142AspArg: 2.142 ± 0.039
3.278AspSer: 3.278 ± 0.064
2.85AspThr: 2.85 ± 0.066
3.98AspVal: 3.98 ± 0.059
0.798AspTrp: 0.798 ± 0.027
2.126AspTyr: 2.126 ± 0.042
0.0AspXaa: 0.0 ± 0.0
Glu
4.67GluAla: 4.67 ± 0.074
0.525GluCys: 0.525 ± 0.02
2.698GluAsp: 2.698 ± 0.054
3.241GluGlu: 3.241 ± 0.065
2.16GluPhe: 2.16 ± 0.039
3.207GluGly: 3.207 ± 0.047
1.59GluHis: 1.59 ± 0.034
3.774GluIle: 3.774 ± 0.052
3.822GluLys: 3.822 ± 0.064
6.553GluLeu: 6.553 ± 0.086
1.646GluMet: 1.646 ± 0.033
2.771GluAsn: 2.771 ± 0.052
1.921GluPro: 1.921 ± 0.044
3.899GluGln: 3.899 ± 0.059
3.068GluArg: 3.068 ± 0.051
3.392GluSer: 3.392 ± 0.052
2.992GluThr: 2.992 ± 0.051
3.852GluVal: 3.852 ± 0.056
0.738GluTrp: 0.738 ± 0.023
1.73GluTyr: 1.73 ± 0.038
0.0GluXaa: 0.0 ± 0.0
Phe
3.499PheAla: 3.499 ± 0.047
0.55PheCys: 0.55 ± 0.02
2.76PheAsp: 2.76 ± 0.047
2.311PheGlu: 2.311 ± 0.037
1.841PhePhe: 1.841 ± 0.042
3.101PheGly: 3.101 ± 0.049
0.837PheHis: 0.837 ± 0.026
3.264PheIle: 3.264 ± 0.052
2.164PheLys: 2.164 ± 0.04
3.368PheLeu: 3.368 ± 0.056
1.044PheMet: 1.044 ± 0.025
2.333PheAsn: 2.333 ± 0.044
1.354PhePro: 1.354 ± 0.032
1.139PheGln: 1.139 ± 0.026
1.407PheArg: 1.407 ± 0.03
3.515PheSer: 3.515 ± 0.049
2.557PheThr: 2.557 ± 0.048
2.755PheVal: 2.755 ± 0.042
0.513PheTrp: 0.513 ± 0.023
1.416PheTyr: 1.416 ± 0.03
0.0PheXaa: 0.0 ± 0.0
Gly
4.832GlyAla: 4.832 ± 0.073
0.985GlyCys: 0.985 ± 0.029
3.673GlyAsp: 3.673 ± 0.088
3.935GlyGlu: 3.935 ± 0.06
3.288GlyPhe: 3.288 ± 0.052
4.49GlyGly: 4.49 ± 0.086
1.508GlyHis: 1.508 ± 0.038
4.938GlyIle: 4.938 ± 0.068
3.987GlyLys: 3.987 ± 0.06
6.774GlyLeu: 6.774 ± 0.08
1.97GlyMet: 1.97 ± 0.038
2.841GlyAsn: 2.841 ± 0.068
1.501GlyPro: 1.501 ± 0.037
2.593GlyGln: 2.593 ± 0.043
2.812GlyArg: 2.812 ± 0.049
3.95GlySer: 3.95 ± 0.074
3.416GlyThr: 3.416 ± 0.072
4.816GlyVal: 4.816 ± 0.06
1.001GlyTrp: 1.001 ± 0.03
2.618GlyTyr: 2.618 ± 0.046
0.0GlyXaa: 0.0 ± 0.0
His
1.612HisAla: 1.612 ± 0.039
0.376HisCys: 0.376 ± 0.02
1.26HisAsp: 1.26 ± 0.032
1.074HisGlu: 1.074 ± 0.032
1.166HisPhe: 1.166 ± 0.027
1.486HisGly: 1.486 ± 0.038
0.812HisHis: 0.812 ± 0.035
1.566HisIle: 1.566 ± 0.036
1.065HisLys: 1.065 ± 0.03
2.186HisLeu: 2.186 ± 0.037
0.485HisMet: 0.485 ± 0.02
1.052HisAsn: 1.052 ± 0.028
1.118HisPro: 1.118 ± 0.03
1.318HisGln: 1.318 ± 0.033
1.038HisArg: 1.038 ± 0.025
1.515HisSer: 1.515 ± 0.034
1.061HisThr: 1.061 ± 0.026
1.325HisVal: 1.325 ± 0.034
0.37HisTrp: 0.37 ± 0.018
0.948HisTyr: 0.948 ± 0.029
0.0HisXaa: 0.0 ± 0.0
Ile
6.722IleAla: 6.722 ± 0.083
0.791IleCys: 0.791 ± 0.026
4.519IleAsp: 4.519 ± 0.066
4.642IleGlu: 4.642 ± 0.07
2.585IlePhe: 2.585 ± 0.046
4.886IleGly: 4.886 ± 0.073
1.391IleHis: 1.391 ± 0.032
4.465IleIle: 4.465 ± 0.075
3.968IleLys: 3.968 ± 0.063
5.498IleLeu: 5.498 ± 0.061
1.393IleMet: 1.393 ± 0.035
3.708IleAsn: 3.708 ± 0.066
2.827IlePro: 2.827 ± 0.049
2.328IleGln: 2.328 ± 0.038
2.68IleArg: 2.68 ± 0.048
5.105IleSer: 5.105 ± 0.068
4.44IleThr: 4.44 ± 0.079
4.372IleVal: 4.372 ± 0.058
0.654IleTrp: 0.654 ± 0.024
1.959IleTyr: 1.959 ± 0.038
0.0IleXaa: 0.0 ± 0.0
Lys
4.963LysAla: 4.963 ± 0.075
0.368LysCys: 0.368 ± 0.016
3.06LysAsp: 3.06 ± 0.053
3.425LysGlu: 3.425 ± 0.052
1.651LysPhe: 1.651 ± 0.039
3.441LysGly: 3.441 ± 0.06
1.331LysHis: 1.331 ± 0.033
3.397LysIle: 3.397 ± 0.05
3.406LysLys: 3.406 ± 0.065
5.554LysLeu: 5.554 ± 0.066
1.559LysMet: 1.559 ± 0.034
2.655LysAsn: 2.655 ± 0.052
2.53LysPro: 2.53 ± 0.05
3.265LysGln: 3.265 ± 0.061
2.679LysArg: 2.679 ± 0.052
3.213LysSer: 3.213 ± 0.052
3.305LysThr: 3.305 ± 0.052
3.952LysVal: 3.952 ± 0.056
0.58LysTrp: 0.58 ± 0.023
1.641LysTyr: 1.641 ± 0.043
0.0LysXaa: 0.0 ± 0.0
Leu
9.501LeuAla: 9.501 ± 0.124
1.127LeuCys: 1.127 ± 0.028
5.673LeuAsp: 5.673 ± 0.064
5.549LeuGlu: 5.549 ± 0.069
4.414LeuPhe: 4.414 ± 0.069
6.608LeuGly: 6.608 ± 0.082
2.024LeuHis: 2.024 ± 0.044
6.592LeuIle: 6.592 ± 0.08
5.446LeuLys: 5.446 ± 0.069
10.638LeuLeu: 10.638 ± 0.144
2.721LeuMet: 2.721 ± 0.049
4.862LeuAsn: 4.862 ± 0.056
4.777LeuPro: 4.777 ± 0.064
3.622LeuGln: 3.622 ± 0.057
4.168LeuArg: 4.168 ± 0.062
7.912LeuSer: 7.912 ± 0.084
6.468LeuThr: 6.468 ± 0.086
6.615LeuVal: 6.615 ± 0.086
1.075LeuTrp: 1.075 ± 0.03
2.694LeuTyr: 2.694 ± 0.046
0.0LeuXaa: 0.0 ± 0.0
Met
2.548MetAla: 2.548 ± 0.052
0.227MetCys: 0.227 ± 0.012
1.221MetAsp: 1.221 ± 0.03
1.231MetGlu: 1.231 ± 0.031
1.012MetPhe: 1.012 ± 0.028
1.739MetGly: 1.739 ± 0.044
0.491MetHis: 0.491 ± 0.018
1.679MetIle: 1.679 ± 0.04
1.614MetLys: 1.614 ± 0.036
2.809MetLeu: 2.809 ± 0.056
0.84MetMet: 0.84 ± 0.028
1.192MetAsn: 1.192 ± 0.03
1.277MetPro: 1.277 ± 0.032
1.019MetGln: 1.019 ± 0.031
1.104MetArg: 1.104 ± 0.031
1.871MetSer: 1.871 ± 0.04
1.723MetThr: 1.723 ± 0.037
1.838MetVal: 1.838 ± 0.037
0.223MetTrp: 0.223 ± 0.013
0.606MetTyr: 0.606 ± 0.02
0.0MetXaa: 0.0 ± 0.0
Asn
3.562AsnAla: 3.562 ± 0.055
0.465AsnCys: 0.465 ± 0.017
2.732AsnAsp: 2.732 ± 0.059
2.611AsnGlu: 2.611 ± 0.044
1.74AsnPhe: 1.74 ± 0.037
3.307AsnGly: 3.307 ± 0.093
1.112AsnHis: 1.112 ± 0.03
3.495AsnIle: 3.495 ± 0.055
2.902AsnLys: 2.902 ± 0.054
4.005AsnLeu: 4.005 ± 0.049
1.096AsnMet: 1.096 ± 0.028
2.764AsnAsn: 2.764 ± 0.069
2.18AsnPro: 2.18 ± 0.041
2.214AsnGln: 2.214 ± 0.045
1.946AsnArg: 1.946 ± 0.039
2.815AsnSer: 2.815 ± 0.053
2.708AsnThr: 2.708 ± 0.066
3.036AsnVal: 3.036 ± 0.056
0.616AsnTrp: 0.616 ± 0.021
1.66AsnTyr: 1.66 ± 0.039
0.0AsnXaa: 0.0 ± 0.0
Pro
3.001ProAla: 3.001 ± 0.049
0.354ProCys: 0.354 ± 0.016
2.223ProAsp: 2.223 ± 0.048
2.969ProGlu: 2.969 ± 0.047
1.767ProPhe: 1.767 ± 0.036
1.982ProGly: 1.982 ± 0.036
0.855ProHis: 0.855 ± 0.025
2.741ProIle: 2.741 ± 0.047
2.012ProLys: 2.012 ± 0.038
4.242ProLeu: 4.242 ± 0.063
0.99ProMet: 0.99 ± 0.027
1.872ProAsn: 1.872 ± 0.036
1.128ProPro: 1.128 ± 0.03
1.732ProGln: 1.732 ± 0.038
1.297ProArg: 1.297 ± 0.028
2.545ProSer: 2.545 ± 0.05
2.339ProThr: 2.339 ± 0.045
3.002ProVal: 3.002 ± 0.05
0.522ProTrp: 0.522 ± 0.02
1.277ProTyr: 1.277 ± 0.033
0.0ProXaa: 0.0 ± 0.0
Gln
4.014GlnAla: 4.014 ± 0.059
0.478GlnCys: 0.478 ± 0.019
1.984GlnAsp: 1.984 ± 0.035
2.202GlnGlu: 2.202 ± 0.043
1.752GlnPhe: 1.752 ± 0.038
2.827GlnGly: 2.827 ± 0.044
1.308GlnHis: 1.308 ± 0.029
2.573GlnIle: 2.573 ± 0.043
2.22GlnLys: 2.22 ± 0.045
5.379GlnLeu: 5.379 ± 0.085
1.11GlnMet: 1.11 ± 0.031
1.656GlnAsn: 1.656 ± 0.038
1.839GlnPro: 1.839 ± 0.041
3.49GlnGln: 3.49 ± 0.1
2.307GlnArg: 2.307 ± 0.052
2.625GlnSer: 2.625 ± 0.047
2.314GlnThr: 2.314 ± 0.046
2.87GlnVal: 2.87 ± 0.047
0.752GlnTrp: 0.752 ± 0.027
1.505GlnTyr: 1.505 ± 0.037
0.0GlnXaa: 0.0 ± 0.0
Arg
3.02ArgAla: 3.02 ± 0.054
0.494ArgCys: 0.494 ± 0.02
2.307ArgAsp: 2.307 ± 0.048
2.662ArgGlu: 2.662 ± 0.063
2.118ArgPhe: 2.118 ± 0.04
2.366ArgGly: 2.366 ± 0.045
1.14ArgHis: 1.14 ± 0.031
2.909ArgIle: 2.909 ± 0.055
2.337ArgLys: 2.337 ± 0.045
4.62ArgLeu: 4.62 ± 0.067
1.124ArgMet: 1.124 ± 0.031
1.846ArgAsn: 1.846 ± 0.041
1.44ArgPro: 1.44 ± 0.028
2.069ArgGln: 2.069 ± 0.048
2.168ArgArg: 2.168 ± 0.044
2.458ArgSer: 2.458 ± 0.049
2.01ArgThr: 2.01 ± 0.037
2.792ArgVal: 2.792 ± 0.049
0.586ArgTrp: 0.586 ± 0.022
1.744ArgTyr: 1.744 ± 0.039
0.0ArgXaa: 0.0 ± 0.0
Ser
5.095SerAla: 5.095 ± 0.07
0.744SerCys: 0.744 ± 0.025
3.789SerAsp: 3.789 ± 0.069
3.741SerGlu: 3.741 ± 0.047
2.878SerPhe: 2.878 ± 0.043
4.695SerGly: 4.695 ± 0.077
1.635SerHis: 1.635 ± 0.038
4.384SerIle: 4.384 ± 0.069
3.345SerLys: 3.345 ± 0.05
7.075SerLeu: 7.075 ± 0.078
1.686SerMet: 1.686 ± 0.034
2.878SerAsn: 2.878 ± 0.061
2.493SerPro: 2.493 ± 0.04
3.108SerGln: 3.108 ± 0.052
2.718SerArg: 2.718 ± 0.047
4.468SerSer: 4.468 ± 0.079
3.565SerThr: 3.565 ± 0.052
4.421SerVal: 4.421 ± 0.056
0.828SerTrp: 0.828 ± 0.025
2.232SerTyr: 2.232 ± 0.042
0.0SerXaa: 0.0 ± 0.0
Thr
4.703ThrAla: 4.703 ± 0.071
0.525ThrCys: 0.525 ± 0.023
3.155ThrAsp: 3.155 ± 0.072
3.171ThrGlu: 3.171 ± 0.045
2.303ThrPhe: 2.303 ± 0.038
4.063ThrGly: 4.063 ± 0.073
1.258ThrHis: 1.258 ± 0.025
3.91ThrIle: 3.91 ± 0.089
2.738ThrLys: 2.738 ± 0.046
6.362ThrLeu: 6.362 ± 0.078
1.241ThrMet: 1.241 ± 0.032
2.355ThrAsn: 2.355 ± 0.055
2.812ThrPro: 2.812 ± 0.05
2.49ThrGln: 2.49 ± 0.046
2.065ThrArg: 2.065 ± 0.038
3.597ThrSer: 3.597 ± 0.06
3.315ThrThr: 3.315 ± 0.073
4.171ThrVal: 4.171 ± 0.08
0.617ThrTrp: 0.617 ± 0.022
1.639ThrTyr: 1.639 ± 0.041
0.0ThrXaa: 0.0 ± 0.0
Val
5.916ValAla: 5.916 ± 0.078
0.784ValCys: 0.784 ± 0.025
4.107ValAsp: 4.107 ± 0.074
4.201ValGlu: 4.201 ± 0.057
2.709ValPhe: 2.709 ± 0.047
4.42ValGly: 4.42 ± 0.055
1.166ValHis: 1.166 ± 0.028
5.181ValIle: 5.181 ± 0.056
3.899ValLys: 3.899 ± 0.057
6.544ValLeu: 6.544 ± 0.083
2.014ValMet: 2.014 ± 0.046
3.221ValAsn: 3.221 ± 0.054
2.53ValPro: 2.53 ± 0.046
2.033ValGln: 2.033 ± 0.04
2.575ValArg: 2.575 ± 0.047
4.686ValSer: 4.686 ± 0.07
4.204ValThr: 4.204 ± 0.078
5.212ValVal: 5.212 ± 0.079
0.754ValTrp: 0.754 ± 0.025
1.836ValTyr: 1.836 ± 0.038
0.0ValXaa: 0.0 ± 0.0
Trp
0.796TrpAla: 0.796 ± 0.025
0.147TrpCys: 0.147 ± 0.01
0.573TrpAsp: 0.573 ± 0.025
0.519TrpGlu: 0.519 ± 0.02
0.593TrpPhe: 0.593 ± 0.02
0.763TrpGly: 0.763 ± 0.025
0.356TrpHis: 0.356 ± 0.016
0.738TrpIle: 0.738 ± 0.025
0.572TrpLys: 0.572 ± 0.021
1.856TrpLeu: 1.856 ± 0.035
0.334TrpMet: 0.334 ± 0.016
0.48TrpAsn: 0.48 ± 0.018
0.455TrpPro: 0.455 ± 0.017
0.939TrpGln: 0.939 ± 0.025
0.638TrpArg: 0.638 ± 0.024
0.729TrpSer: 0.729 ± 0.027
0.504TrpThr: 0.504 ± 0.023
0.798TrpVal: 0.798 ± 0.024
0.198TrpTrp: 0.198 ± 0.013
0.371TrpTyr: 0.371 ± 0.016
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.197TyrAla: 2.197 ± 0.04
0.422TyrCys: 0.422 ± 0.017
1.77TyrAsp: 1.77 ± 0.044
1.461TyrGlu: 1.461 ± 0.034
1.501TyrPhe: 1.501 ± 0.035
2.16TyrGly: 2.16 ± 0.041
0.831TyrHis: 0.831 ± 0.027
1.986TyrIle: 1.986 ± 0.043
1.544TyrLys: 1.544 ± 0.033
3.499TyrLeu: 3.499 ± 0.051
0.684TyrMet: 0.684 ± 0.022
1.427TyrAsn: 1.427 ± 0.033
1.376TyrPro: 1.376 ± 0.028
1.958TyrGln: 1.958 ± 0.042
1.705TyrArg: 1.705 ± 0.034
2.229TyrSer: 2.229 ± 0.045
1.632TyrThr: 1.632 ± 0.04
1.846TyrVal: 1.846 ± 0.036
0.486TyrTrp: 0.486 ± 0.018
1.102TyrTyr: 1.102 ± 0.032
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4552 proteins (1430277 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski