Amino acid dipepetide frequency for Limnoraphis robusta CS-951

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.842AlaAla: 5.842 ± 0.078	0.794AlaCys: 0.794 ± 0.024	3.633AlaAsp: 3.633 ± 0.063	5.354AlaGlu: 5.354 ± 0.07	2.898AlaPhe: 2.898 ± 0.045	4.759AlaGly: 4.759 ± 0.066	1.204AlaHis: 1.204 ± 0.028	6.301AlaIle: 6.301 ± 0.071	3.805AlaLys: 3.805 ± 0.058	7.818AlaLeu: 7.818 ± 0.083	1.472AlaMet: 1.472 ± 0.029	3.247AlaAsn: 3.247 ± 0.078	2.25AlaPro: 2.25 ± 0.045	3.783AlaGln: 3.783 ± 0.055	3.086AlaArg: 3.086 ± 0.046	4.477AlaSer: 4.477 ± 0.061	4.168AlaThr: 4.168 ± 0.056	5.15AlaVal: 5.15 ± 0.067	1.017AlaTrp: 1.017 ± 0.03	2.199AlaTyr: 2.199 ± 0.04	0.009AlaXaa: 0.009 ± 0.002
Cys	0.536CysAla: 0.536 ± 0.02	0.167CysCys: 0.167 ± 0.01	0.568CysAsp: 0.568 ± 0.022	0.591CysGlu: 0.591 ± 0.021	0.455CysPhe: 0.455 ± 0.018	0.83CysGly: 0.83 ± 0.027	0.291CysHis: 0.291 ± 0.014	0.583CysIle: 0.583 ± 0.019	0.448CysLys: 0.448 ± 0.018	1.217CysLeu: 1.217 ± 0.031	0.146CysMet: 0.146 ± 0.01	0.367CysAsn: 0.367 ± 0.016	0.566CysPro: 0.566 ± 0.022	0.701CysGln: 0.701 ± 0.022	0.528CysArg: 0.528 ± 0.016	0.689CysSer: 0.689 ± 0.02	0.438CysThr: 0.438 ± 0.017	0.607CysVal: 0.607 ± 0.021	0.161CysTrp: 0.161 ± 0.01	0.405CysTyr: 0.405 ± 0.017	0.001CysXaa: 0.001 ± 0.001
Asp	3.281AspAla: 3.281 ± 0.046	0.594AspCys: 0.594 ± 0.019	2.348AspAsp: 2.348 ± 0.061	3.34AspGlu: 3.34 ± 0.051	2.368AspPhe: 2.368 ± 0.044	3.18AspGly: 3.18 ± 0.077	0.884AspHis: 0.884 ± 0.026	3.256AspIle: 3.256 ± 0.053	1.911AspLys: 1.911 ± 0.036	5.922AspLeu: 5.922 ± 0.081	0.682AspMet: 0.682 ± 0.021	1.968AspAsn: 1.968 ± 0.046	2.445AspPro: 2.445 ± 0.044	2.425AspGln: 2.425 ± 0.041	2.921AspArg: 2.921 ± 0.05	3.076AspSer: 3.076 ± 0.047	2.264AspThr: 2.264 ± 0.05	2.965AspVal: 2.965 ± 0.045	0.917AspTrp: 0.917 ± 0.025	1.904AspTyr: 1.904 ± 0.035	0.007AspXaa: 0.007 ± 0.002
Glu	5.644GluAla: 5.644 ± 0.07	0.469GluCys: 0.469 ± 0.018	3.127GluAsp: 3.127 ± 0.047	4.465GluGlu: 4.465 ± 0.063	2.716GluPhe: 2.716 ± 0.046	3.533GluGly: 3.533 ± 0.05	1.037GluHis: 1.037 ± 0.027	5.358GluIle: 5.358 ± 0.07	3.95GluLys: 3.95 ± 0.065	6.954GluLeu: 6.954 ± 0.074	1.509GluMet: 1.509 ± 0.036	3.396GluAsn: 3.396 ± 0.057	2.694GluPro: 2.694 ± 0.043	4.042GluGln: 4.042 ± 0.063	3.55GluArg: 3.55 ± 0.051	3.652GluSer: 3.652 ± 0.051	4.155GluThr: 4.155 ± 0.055	4.362GluVal: 4.362 ± 0.055	0.862GluTrp: 0.862 ± 0.022	1.992GluTyr: 1.992 ± 0.041	0.014GluXaa: 0.014 ± 0.003
Phe	2.759PheAla: 2.759 ± 0.041	0.555PheCys: 0.555 ± 0.021	2.277PheAsp: 2.277 ± 0.039	2.606PheGlu: 2.606 ± 0.041	1.769PhePhe: 1.769 ± 0.039	2.886PheGly: 2.886 ± 0.05	0.744PheHis: 0.744 ± 0.024	2.652PheIle: 2.652 ± 0.052	1.926PheLys: 1.926 ± 0.043	4.255PheLeu: 4.255 ± 0.054	0.68PheMet: 0.68 ± 0.022	1.903PheAsn: 1.903 ± 0.038	1.971PhePro: 1.971 ± 0.034	1.926PheGln: 1.926 ± 0.035	1.831PheArg: 1.831 ± 0.035	3.2PheSer: 3.2 ± 0.049	2.165PheThr: 2.165 ± 0.038	2.533PheVal: 2.533 ± 0.042	0.755PheTrp: 0.755 ± 0.027	1.526PheTyr: 1.526 ± 0.035	0.005PheXaa: 0.005 ± 0.002
Gly	4.138GlyAla: 4.138 ± 0.072	0.828GlyCys: 0.828 ± 0.025	3.209GlyAsp: 3.209 ± 0.061	4.542GlyGlu: 4.542 ± 0.054	3.031GlyPhe: 3.031 ± 0.045	4.582GlyGly: 4.582 ± 0.085	1.125GlyHis: 1.125 ± 0.033	4.968GlyIle: 4.968 ± 0.06	3.625GlyLys: 3.625 ± 0.054	6.865GlyLeu: 6.865 ± 0.075	1.44GlyMet: 1.44 ± 0.034	3.02GlyAsn: 3.02 ± 0.081	1.251GlyPro: 1.251 ± 0.029	2.915GlyGln: 2.915 ± 0.055	3.032GlyArg: 3.032 ± 0.051	4.104GlySer: 4.104 ± 0.062	3.62GlyThr: 3.62 ± 0.064	4.62GlyVal: 4.62 ± 0.063	1.126GlyTrp: 1.126 ± 0.026	2.437GlyTyr: 2.437 ± 0.047	0.007GlyXaa: 0.007 ± 0.002
His	0.983HisAla: 0.983 ± 0.028	0.33HisCys: 0.33 ± 0.014	0.685HisAsp: 0.685 ± 0.022	0.822HisGlu: 0.822 ± 0.027	0.876HisPhe: 0.876 ± 0.023	0.956HisGly: 0.956 ± 0.023	0.668HisHis: 0.668 ± 0.027	0.983HisIle: 0.983 ± 0.022	0.788HisLys: 0.788 ± 0.026	2.415HisLeu: 2.415 ± 0.046	0.225HisMet: 0.225 ± 0.013	0.707HisAsn: 0.707 ± 0.023	1.457HisPro: 1.457 ± 0.033	1.377HisGln: 1.377 ± 0.028	1.153HisArg: 1.153 ± 0.027	1.254HisSer: 1.254 ± 0.029	0.794HisThr: 0.794 ± 0.023	0.755HisVal: 0.755 ± 0.021	0.359HisTrp: 0.359 ± 0.016	0.701HisTyr: 0.701 ± 0.024	0.004HisXaa: 0.004 ± 0.002
Ile	6.28IleAla: 6.28 ± 0.068	0.741IleCys: 0.741 ± 0.02	3.777IleAsp: 3.777 ± 0.047	4.763IleGlu: 4.763 ± 0.058	2.749IlePhe: 2.749 ± 0.053	4.412IleGly: 4.412 ± 0.054	1.27IleHis: 1.27 ± 0.029	4.248IleIle: 4.248 ± 0.064	3.156IleLys: 3.156 ± 0.048	7.454IleLeu: 7.454 ± 0.084	0.838IleMet: 0.838 ± 0.024	3.177IleAsn: 3.177 ± 0.055	3.791IlePro: 3.791 ± 0.047	3.397IleGln: 3.397 ± 0.061	3.256IleArg: 3.256 ± 0.047	4.756IleSer: 4.756 ± 0.05	3.86IleThr: 3.86 ± 0.053	4.3IleVal: 4.3 ± 0.058	0.862IleTrp: 0.862 ± 0.021	1.979IleTyr: 1.979 ± 0.038	0.006IleXaa: 0.006 ± 0.002
Lys	3.952LysAla: 3.952 ± 0.06	0.357LysCys: 0.357 ± 0.017	2.027LysAsp: 2.027 ± 0.043	2.577LysGlu: 2.577 ± 0.047	1.778LysPhe: 1.778 ± 0.037	2.599LysGly: 2.599 ± 0.043	0.818LysHis: 0.818 ± 0.023	3.762LysIle: 3.762 ± 0.055	2.552LysLys: 2.552 ± 0.052	5.614LysLeu: 5.614 ± 0.074	0.951LysMet: 0.951 ± 0.026	2.369LysAsn: 2.369 ± 0.045	2.69LysPro: 2.69 ± 0.044	2.978LysGln: 2.978 ± 0.045	2.507LysArg: 2.507 ± 0.043	3.028LysSer: 3.028 ± 0.043	3.329LysThr: 3.329 ± 0.054	3.117LysVal: 3.117 ± 0.053	0.498LysTrp: 0.498 ± 0.016	1.367LysTyr: 1.367 ± 0.034	0.008LysXaa: 0.008 ± 0.002
Leu	8.791LeuAla: 8.791 ± 0.084	1.019LeuCys: 1.019 ± 0.028	5.325LeuAsp: 5.325 ± 0.054	8.231LeuGlu: 8.231 ± 0.083	4.065LeuPhe: 4.065 ± 0.061	7.336LeuGly: 7.336 ± 0.081	1.823LeuHis: 1.823 ± 0.035	7.396LeuIle: 7.396 ± 0.075	6.224LeuLys: 6.224 ± 0.065	10.749LeuLeu: 10.749 ± 0.112	2.194LeuMet: 2.194 ± 0.04	5.275LeuAsn: 5.275 ± 0.071	5.2LeuPro: 5.2 ± 0.069	5.522LeuGln: 5.522 ± 0.059	5.252LeuArg: 5.252 ± 0.066	8.115LeuSer: 8.115 ± 0.082	6.687LeuThr: 6.687 ± 0.071	6.533LeuVal: 6.533 ± 0.063	1.453LeuTrp: 1.453 ± 0.039	2.921LeuTyr: 2.921 ± 0.051	0.011LeuXaa: 0.011 ± 0.002
Met	1.6MetAla: 1.6 ± 0.039	0.106MetCys: 0.106 ± 0.009	0.712MetAsp: 0.712 ± 0.023	0.961MetGlu: 0.961 ± 0.028	0.581MetPhe: 0.581 ± 0.018	1.463MetGly: 1.463 ± 0.033	0.219MetHis: 0.219 ± 0.013	1.368MetIle: 1.368 ± 0.033	0.993MetLys: 0.993 ± 0.024	1.822MetLeu: 1.822 ± 0.034	0.43MetMet: 0.43 ± 0.017	0.948MetAsn: 0.948 ± 0.031	0.8MetPro: 0.8 ± 0.024	0.839MetGln: 0.839 ± 0.023	0.916MetArg: 0.916 ± 0.028	1.33MetSer: 1.33 ± 0.03	1.249MetThr: 1.249 ± 0.03	1.188MetVal: 1.188 ± 0.029	0.158MetTrp: 0.158 ± 0.011	0.365MetTyr: 0.365 ± 0.015	0.003MetXaa: 0.003 ± 0.001
Asn	2.766AsnAla: 2.766 ± 0.048	0.614AsnCys: 0.614 ± 0.023	1.883AsnAsp: 1.883 ± 0.063	1.904AsnGlu: 1.904 ± 0.037	1.938AsnPhe: 1.938 ± 0.034	2.596AsnGly: 2.596 ± 0.047	1.0AsnHis: 1.0 ± 0.027	3.078AsnIle: 3.078 ± 0.059	1.756AsnLys: 1.756 ± 0.036	5.927AsnLeu: 5.927 ± 0.105	0.592AsnMet: 0.592 ± 0.019	2.034AsnAsn: 2.034 ± 0.054	3.07AsnPro: 3.07 ± 0.039	2.866AsnGln: 2.866 ± 0.052	2.564AsnArg: 2.564 ± 0.042	3.358AsnSer: 3.358 ± 0.06	2.307AsnThr: 2.307 ± 0.045	2.198AsnVal: 2.198 ± 0.041	0.811AsnTrp: 0.811 ± 0.027	1.53AsnTyr: 1.53 ± 0.033	0.004AsnXaa: 0.004 ± 0.002
Pro	2.799ProAla: 2.799 ± 0.039	0.373ProCys: 0.373 ± 0.017	3.076ProAsp: 3.076 ± 0.053	4.378ProGlu: 4.378 ± 0.052	1.804ProPhe: 1.804 ± 0.034	2.835ProGly: 2.835 ± 0.043	0.884ProHis: 0.884 ± 0.023	2.993ProIle: 2.993 ± 0.044	2.223ProLys: 2.223 ± 0.046	4.823ProLeu: 4.823 ± 0.061	0.755ProMet: 0.755 ± 0.025	2.311ProAsn: 2.311 ± 0.043	2.358ProPro: 2.358 ± 0.05	2.762ProGln: 2.762 ± 0.044	1.758ProArg: 1.758 ± 0.037	3.098ProSer: 3.098 ± 0.049	2.882ProThr: 2.882 ± 0.068	3.212ProVal: 3.212 ± 0.043	0.579ProTrp: 0.579 ± 0.021	1.315ProTyr: 1.315 ± 0.032	0.002ProXaa: 0.002 ± 0.001
Gln	4.896GlnAla: 4.896 ± 0.061	0.346GlnCys: 0.346 ± 0.014	2.228GlnAsp: 2.228 ± 0.035	3.56GlnGlu: 3.56 ± 0.055	2.216GlnPhe: 2.216 ± 0.037	3.398GlnGly: 3.398 ± 0.052	0.903GlnHis: 0.903 ± 0.024	3.712GlnIle: 3.712 ± 0.048	2.947GlnLys: 2.947 ± 0.052	6.54GlnLeu: 6.54 ± 0.075	1.157GlnMet: 1.157 ± 0.028	2.324GlnAsn: 2.324 ± 0.04	2.774GlnPro: 2.774 ± 0.049	4.186GlnGln: 4.186 ± 0.084	2.862GlnArg: 2.862 ± 0.046	3.109GlnSer: 3.109 ± 0.049	3.408GlnThr: 3.408 ± 0.048	3.947GlnVal: 3.947 ± 0.052	0.759GlnTrp: 0.759 ± 0.024	1.46GlnTyr: 1.46 ± 0.031	0.003GlnXaa: 0.003 ± 0.001
Arg	2.813ArgAla: 2.813 ± 0.042	0.512ArgCys: 0.512 ± 0.02	2.426ArgAsp: 2.426 ± 0.044	3.359ArgGlu: 3.359 ± 0.049	2.283ArgPhe: 2.283 ± 0.041	2.896ArgGly: 2.896 ± 0.054	0.955ArgHis: 0.955 ± 0.025	3.299ArgIle: 3.299 ± 0.044	2.342ArgLys: 2.342 ± 0.047	5.938ArgLeu: 5.938 ± 0.062	0.987ArgMet: 0.987 ± 0.024	2.002ArgAsn: 2.002 ± 0.037	1.904ArgPro: 1.904 ± 0.042	3.315ArgGln: 3.315 ± 0.047	2.994ArgArg: 2.994 ± 0.052	3.29ArgSer: 3.29 ± 0.054	2.46ArgThr: 2.46 ± 0.039	3.386ArgVal: 3.386 ± 0.051	0.818ArgTrp: 0.818 ± 0.021	1.974ArgTyr: 1.974 ± 0.038	0.004ArgXaa: 0.004 ± 0.002
Ser	4.156SerAla: 4.156 ± 0.056	0.672SerCys: 0.672 ± 0.024	3.42SerAsp: 3.42 ± 0.055	4.649SerGlu: 4.649 ± 0.066	2.618SerPhe: 2.618 ± 0.048	4.539SerGly: 4.539 ± 0.061	1.286SerHis: 1.286 ± 0.03	4.077SerIle: 4.077 ± 0.056	2.72SerLys: 2.72 ± 0.045	7.49SerLeu: 7.49 ± 0.073	1.141SerMet: 1.141 ± 0.027	2.774SerAsn: 2.774 ± 0.047	3.678SerPro: 3.678 ± 0.053	4.318SerGln: 4.318 ± 0.067	3.41SerArg: 3.41 ± 0.05	4.847SerSer: 4.847 ± 0.075	3.511SerThr: 3.511 ± 0.052	4.045SerVal: 4.045 ± 0.056	0.937SerTrp: 0.937 ± 0.026	1.883SerTyr: 1.883 ± 0.036	0.006SerXaa: 0.006 ± 0.002
Thr	4.331ThrAla: 4.331 ± 0.057	0.521ThrCys: 0.521 ± 0.017	2.677ThrAsp: 2.677 ± 0.048	3.749ThrGlu: 3.749 ± 0.055	2.129ThrPhe: 2.129 ± 0.041	4.288ThrGly: 4.288 ± 0.062	1.11ThrHis: 1.11 ± 0.024	3.794ThrIle: 3.794 ± 0.062	1.956ThrLys: 1.956 ± 0.039	6.665ThrLeu: 6.665 ± 0.067	0.729ThrMet: 0.729 ± 0.023	1.989ThrAsn: 1.989 ± 0.045	3.53ThrPro: 3.53 ± 0.071	3.243ThrGln: 3.243 ± 0.048	2.376ThrArg: 2.376 ± 0.038	3.396ThrSer: 3.396 ± 0.052	3.059ThrThr: 3.059 ± 0.05	4.21ThrVal: 4.21 ± 0.06	0.739ThrTrp: 0.739 ± 0.023	1.486ThrTyr: 1.486 ± 0.031	0.006ThrXaa: 0.006 ± 0.002
Val	5.032ValAla: 5.032 ± 0.071	0.721ValCys: 0.721 ± 0.024	3.221ValAsp: 3.221 ± 0.048	4.825ValGlu: 4.825 ± 0.062	2.601ValPhe: 2.601 ± 0.042	4.416ValGly: 4.416 ± 0.064	1.026ValHis: 1.026 ± 0.026	4.589ValIle: 4.589 ± 0.056	3.409ValLys: 3.409 ± 0.054	6.279ValLeu: 6.279 ± 0.072	1.34ValMet: 1.34 ± 0.03	2.968ValAsn: 2.968 ± 0.051	2.644ValPro: 2.644 ± 0.046	2.895ValGln: 2.895 ± 0.048	3.147ValArg: 3.147 ± 0.046	4.376ValSer: 4.376 ± 0.053	3.42ValThr: 3.42 ± 0.053	4.374ValVal: 4.374 ± 0.06	0.854ValTrp: 0.854 ± 0.03	1.912ValTyr: 1.912 ± 0.034	0.006ValXaa: 0.006 ± 0.002
Trp	0.809TrpAla: 0.809 ± 0.02	0.158TrpCys: 0.158 ± 0.011	0.596TrpAsp: 0.596 ± 0.024	0.972TrpGlu: 0.972 ± 0.023	0.635TrpPhe: 0.635 ± 0.021	1.014TrpGly: 1.014 ± 0.025	0.286TrpHis: 0.286 ± 0.013	0.928TrpIle: 0.928 ± 0.023	0.821TrpLys: 0.821 ± 0.024	1.822TrpLeu: 1.822 ± 0.036	0.383TrpMet: 0.383 ± 0.015	0.709TrpAsn: 0.709 ± 0.026	0.366TrpPro: 0.366 ± 0.014	0.994TrpGln: 0.994 ± 0.025	0.758TrpArg: 0.758 ± 0.023	0.852TrpSer: 0.852 ± 0.025	0.646TrpThr: 0.646 ± 0.02	1.037TrpVal: 1.037 ± 0.029	0.222TrpTrp: 0.222 ± 0.014	0.439TrpTyr: 0.439 ± 0.02	0.002TrpXaa: 0.002 ± 0.001
Tyr	1.855TyrAla: 1.855 ± 0.041	0.418TyrCys: 0.418 ± 0.015	1.439TyrAsp: 1.439 ± 0.032	1.828TyrGlu: 1.828 ± 0.035	1.406TyrPhe: 1.406 ± 0.031	1.961TyrGly: 1.961 ± 0.036	0.755TyrHis: 0.755 ± 0.023	1.723TyrIle: 1.723 ± 0.034	1.322TyrLys: 1.322 ± 0.035	3.54TyrLeu: 3.54 ± 0.044	0.392TyrMet: 0.392 ± 0.016	1.299TyrAsn: 1.299 ± 0.026	1.776TyrPro: 1.776 ± 0.034	2.245TyrGln: 2.245 ± 0.041	2.049TyrArg: 2.049 ± 0.037	2.163TyrSer: 2.163 ± 0.044	1.556TyrThr: 1.556 ± 0.032	1.509TyrVal: 1.509 ± 0.029	0.559TyrTrp: 0.559 ± 0.02	1.188TyrTyr: 1.188 ± 0.029	0.006TyrXaa: 0.006 ± 0.002
Xaa	0.004XaaAla: 0.004 ± 0.002	0.002XaaCys: 0.002 ± 0.001	0.005XaaAsp: 0.005 ± 0.002	0.005XaaGlu: 0.005 ± 0.002	0.006XaaPhe: 0.006 ± 0.002	0.005XaaGly: 0.005 ± 0.002	0.004XaaHis: 0.004 ± 0.002	0.007XaaIle: 0.007 ± 0.002	0.002XaaLys: 0.002 ± 0.001	0.017XaaLeu: 0.017 ± 0.004	0.006XaaMet: 0.006 ± 0.002	0.008XaaAsn: 0.008 ± 0.002	0.004XaaPro: 0.004 ± 0.001	0.006XaaGln: 0.006 ± 0.002	0.007XaaArg: 0.007 ± 0.002	0.009XaaSer: 0.009 ± 0.002	0.004XaaThr: 0.004 ± 0.001	0.009XaaVal: 0.009 ± 0.002	0.002XaaTrp: 0.002 ± 0.001	0.004XaaTyr: 0.004 ± 0.002	0.006XaaXaa: 0.006 ± 0.003

Statistics based on 5035 proteins (1616785 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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