Amino acid dipepetide frequency for Taishun Tick Virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.912AlaAla: 6.912 ± 4.857
1.885AlaCys: 1.885 ± 1.259
3.456AlaAsp: 3.456 ± 0.707
0.943AlaGlu: 0.943 ± 0.935
0.943AlaPhe: 0.943 ± 0.929
4.398AlaGly: 4.398 ± 2.169
0.314AlaHis: 0.314 ± 0.162
4.713AlaIle: 4.713 ± 0.738
3.142AlaLys: 3.142 ± 1.77
6.598AlaLeu: 6.598 ± 0.695
0.628AlaMet: 0.628 ± 0.42
1.257AlaAsn: 1.257 ± 0.386
2.513AlaPro: 2.513 ± 2.074
4.084AlaGln: 4.084 ± 1.342
2.513AlaArg: 2.513 ± 1.678
5.341AlaSer: 5.341 ± 2.114
8.483AlaThr: 8.483 ± 3.729
3.77AlaVal: 3.77 ± 0.838
0.628AlaTrp: 0.628 ± 0.325
1.571AlaTyr: 1.571 ± 0.463
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.943CysCys: 0.943 ± 0.358
0.0CysAsp: 0.0 ± 0.0
0.628CysGlu: 0.628 ± 0.325
1.571CysPhe: 1.571 ± 0.268
0.943CysGly: 0.943 ± 0.487
0.628CysHis: 0.628 ± 0.42
0.628CysIle: 0.628 ± 0.42
1.257CysLys: 1.257 ± 0.839
2.513CysLeu: 2.513 ± 1.299
0.314CysMet: 0.314 ± 0.162
0.628CysAsn: 0.628 ± 0.325
0.628CysPro: 0.628 ± 0.325
0.628CysGln: 0.628 ± 0.325
0.628CysArg: 0.628 ± 0.42
1.257CysSer: 1.257 ± 0.839
0.0CysThr: 0.0 ± 0.0
1.257CysVal: 1.257 ± 0.367
0.0CysTrp: 0.0 ± 0.0
0.943CysTyr: 0.943 ± 0.487
0.0CysXaa: 0.0 ± 0.0
Asp
1.571AspAla: 1.571 ± 1.347
0.943AspCys: 0.943 ± 0.369
3.142AspAsp: 3.142 ± 0.879
3.142AspGlu: 3.142 ± 2.782
4.398AspPhe: 4.398 ± 1.759
1.885AspGly: 1.885 ± 0.739
2.199AspHis: 2.199 ± 0.684
1.885AspIle: 1.885 ± 0.552
3.142AspLys: 3.142 ± 1.521
7.226AspLeu: 7.226 ± 0.317
0.628AspMet: 0.628 ± 0.42
0.943AspAsn: 0.943 ± 0.487
4.713AspPro: 4.713 ± 1.51
1.885AspGln: 1.885 ± 0.717
1.885AspArg: 1.885 ± 0.552
2.828AspSer: 2.828 ± 0.793
1.257AspThr: 1.257 ± 0.367
2.828AspVal: 2.828 ± 1.921
1.257AspTrp: 1.257 ± 0.386
3.142AspTyr: 3.142 ± 0.925
0.0AspXaa: 0.0 ± 0.0
Glu
4.398GluAla: 4.398 ± 0.572
0.314GluCys: 0.314 ± 0.162
4.084GluAsp: 4.084 ± 1.333
4.398GluGlu: 4.398 ± 2.045
4.084GluPhe: 4.084 ± 0.63
5.655GluGly: 5.655 ± 1.586
1.257GluHis: 1.257 ± 1.037
2.828GluIle: 2.828 ± 1.641
1.571GluLys: 1.571 ± 0.268
5.027GluLeu: 5.027 ± 1.06
1.571GluMet: 1.571 ± 0.268
0.943GluAsn: 0.943 ± 0.929
2.199GluPro: 2.199 ± 0.598
0.628GluGln: 0.628 ± 0.325
1.571GluArg: 1.571 ± 0.812
5.027GluSer: 5.027 ± 1.555
5.027GluThr: 5.027 ± 0.809
2.828GluVal: 2.828 ± 1.913
0.0GluTrp: 0.0 ± 0.0
2.199GluTyr: 2.199 ± 0.737
0.0GluXaa: 0.0 ± 0.0
Phe
3.142PheAla: 3.142 ± 0.544
0.628PheCys: 0.628 ± 0.42
0.943PheAsp: 0.943 ± 0.369
2.828PheGlu: 2.828 ± 0.382
2.513PhePhe: 2.513 ± 1.299
5.027PheGly: 5.027 ± 1.026
1.257PheHis: 1.257 ± 0.649
2.513PheIle: 2.513 ± 0.49
3.142PheLys: 3.142 ± 0.38
5.969PheLeu: 5.969 ± 1.483
1.571PheMet: 1.571 ± 0.268
1.885PheAsn: 1.885 ± 0.739
4.084PhePro: 4.084 ± 1.128
0.943PheGln: 0.943 ± 0.487
3.142PheArg: 3.142 ± 0.925
3.77PheSer: 3.77 ± 0.77
1.571PheThr: 1.571 ± 0.439
3.456PheVal: 3.456 ± 1.786
1.257PheTrp: 1.257 ± 0.649
1.257PheTyr: 1.257 ± 0.367
0.0PheXaa: 0.0 ± 0.0
Gly
5.341GlyAla: 5.341 ± 1.074
0.628GlyCys: 0.628 ± 0.325
3.456GlyAsp: 3.456 ± 0.374
3.142GlyGlu: 3.142 ± 1.77
1.257GlyPhe: 1.257 ± 0.43
3.456GlyGly: 3.456 ± 0.978
1.257GlyHis: 1.257 ± 0.367
4.713GlyIle: 4.713 ± 1.388
3.77GlyLys: 3.77 ± 1.866
7.854GlyLeu: 7.854 ± 2.704
0.628GlyMet: 0.628 ± 0.325
2.828GlyAsn: 2.828 ± 0.698
1.885GlyPro: 1.885 ± 1.869
1.885GlyGln: 1.885 ± 0.106
2.828GlyArg: 2.828 ± 0.977
5.341GlySer: 5.341 ± 2.114
4.398GlyThr: 4.398 ± 0.765
2.828GlyVal: 2.828 ± 0.382
0.628GlyTrp: 0.628 ± 0.325
1.257GlyTyr: 1.257 ± 0.386
0.0GlyXaa: 0.0 ± 0.0
His
1.257HisAla: 1.257 ± 0.43
0.0HisCys: 0.0 ± 0.0
0.314HisAsp: 0.314 ± 0.162
2.199HisGlu: 2.199 ± 0.606
0.943HisPhe: 0.943 ± 0.487
1.257HisGly: 1.257 ± 0.649
0.314HisHis: 0.314 ± 0.162
1.257HisIle: 1.257 ± 0.649
0.314HisLys: 0.314 ± 0.162
2.199HisLeu: 2.199 ± 1.022
0.314HisMet: 0.314 ± 0.524
0.943HisAsn: 0.943 ± 0.369
2.199HisPro: 2.199 ± 0.707
1.571HisGln: 1.571 ± 0.463
1.885HisArg: 1.885 ± 0.576
1.885HisSer: 1.885 ± 0.552
1.257HisThr: 1.257 ± 0.43
0.943HisVal: 0.943 ± 0.487
0.628HisTrp: 0.628 ± 0.42
0.628HisTyr: 0.628 ± 0.42
0.0HisXaa: 0.0 ± 0.0
Ile
1.571IleAla: 1.571 ± 0.463
0.943IleCys: 0.943 ± 0.369
2.199IleAsp: 2.199 ± 0.598
2.199IleGlu: 2.199 ± 0.709
3.142IlePhe: 3.142 ± 0.925
2.199IleGly: 2.199 ± 0.606
1.571IleHis: 1.571 ± 1.522
3.456IleIle: 3.456 ± 1.309
3.456IleLys: 3.456 ± 0.796
6.283IleLeu: 6.283 ± 1.48
1.257IleMet: 1.257 ± 0.367
2.199IleAsn: 2.199 ± 0.709
4.398IlePro: 4.398 ± 1.759
3.142IleGln: 3.142 ± 1.154
4.398IleArg: 4.398 ± 0.765
4.713IleSer: 4.713 ± 1.56
4.398IleThr: 4.398 ± 1.194
1.571IleVal: 1.571 ± 0.463
0.628IleTrp: 0.628 ± 1.037
1.257IleTyr: 1.257 ± 0.367
0.0IleXaa: 0.0 ± 0.0
Lys
2.513LysAla: 2.513 ± 1.771
0.628LysCys: 0.628 ± 0.325
1.885LysAsp: 1.885 ± 0.974
3.77LysGlu: 3.77 ± 0.212
1.885LysPhe: 1.885 ± 1.382
1.885LysGly: 1.885 ± 0.739
0.314LysHis: 0.314 ± 0.162
3.456LysIle: 3.456 ± 1.032
2.199LysLys: 2.199 ± 0.709
6.598LysLeu: 6.598 ± 1.8
1.571LysMet: 1.571 ± 0.268
2.828LysAsn: 2.828 ± 1.007
1.571LysPro: 1.571 ± 0.463
2.828LysGln: 2.828 ± 1.921
1.885LysArg: 1.885 ± 0.576
4.713LysSer: 4.713 ± 1.085
2.513LysThr: 2.513 ± 1.123
4.713LysVal: 4.713 ± 0.803
0.628LysTrp: 0.628 ± 0.419
0.628LysTyr: 0.628 ± 0.325
0.0LysXaa: 0.0 ± 0.0
Leu
8.797LeuAla: 8.797 ± 2.703
1.257LeuCys: 1.257 ± 0.367
6.912LeuAsp: 6.912 ± 0.337
5.341LeuGlu: 5.341 ± 1.213
5.969LeuPhe: 5.969 ± 0.927
5.655LeuGly: 5.655 ± 0.757
3.142LeuHis: 3.142 ± 0.906
6.598LeuIle: 6.598 ± 2.33
4.713LeuLys: 4.713 ± 0.803
10.368LeuLeu: 10.368 ± 2.12
2.513LeuMet: 2.513 ± 0.852
5.655LeuAsn: 5.655 ± 2.399
5.969LeuPro: 5.969 ± 2.128
3.142LeuGln: 3.142 ± 0.544
8.483LeuArg: 8.483 ± 1.015
8.168LeuSer: 8.168 ± 1.548
7.226LeuThr: 7.226 ± 1.118
6.283LeuVal: 6.283 ± 0.684
0.943LeuTrp: 0.943 ± 0.487
3.77LeuTyr: 3.77 ± 1.948
0.0LeuXaa: 0.0 ± 0.0
Met
3.456MetAla: 3.456 ± 0.374
0.314MetCys: 0.314 ± 0.162
1.571MetAsp: 1.571 ± 1.347
0.943MetGlu: 0.943 ± 0.592
0.628MetPhe: 0.628 ± 0.42
1.571MetGly: 1.571 ± 0.268
0.314MetHis: 0.314 ± 0.518
0.943MetIle: 0.943 ± 0.487
1.571MetLys: 1.571 ± 0.463
0.628MetLeu: 0.628 ± 1.048
0.628MetMet: 0.628 ± 0.325
0.628MetAsn: 0.628 ± 0.325
0.314MetPro: 0.314 ± 0.524
0.943MetGln: 0.943 ± 0.487
0.628MetArg: 0.628 ± 0.42
1.885MetSer: 1.885 ± 0.106
1.885MetThr: 1.885 ± 1.259
1.257MetVal: 1.257 ± 0.386
0.314MetTrp: 0.314 ± 0.162
0.943MetTyr: 0.943 ± 0.487
0.0MetXaa: 0.0 ± 0.0
Asn
1.257AsnAla: 1.257 ± 0.839
0.314AsnCys: 0.314 ± 0.162
2.199AsnAsp: 2.199 ± 0.709
1.885AsnGlu: 1.885 ± 0.106
1.257AsnPhe: 1.257 ± 0.43
0.943AsnGly: 0.943 ± 0.929
1.885AsnHis: 1.885 ± 0.974
2.199AsnIle: 2.199 ± 0.709
1.257AsnLys: 1.257 ± 0.367
5.655AsnLeu: 5.655 ± 1.368
0.314AsnMet: 0.314 ± 0.162
1.257AsnAsn: 1.257 ± 0.649
4.398AsnPro: 4.398 ± 0.765
0.628AsnGln: 0.628 ± 0.419
2.513AsnArg: 2.513 ± 0.474
2.199AsnSer: 2.199 ± 1.137
1.885AsnThr: 1.885 ± 0.106
1.257AsnVal: 1.257 ± 0.839
0.943AsnTrp: 0.943 ± 0.487
1.257AsnTyr: 1.257 ± 0.649
0.0AsnXaa: 0.0 ± 0.0
Pro
2.199ProAla: 2.199 ± 1.251
1.257ProCys: 1.257 ± 0.367
4.398ProAsp: 4.398 ± 1.14
3.456ProGlu: 3.456 ± 0.978
1.571ProPhe: 1.571 ± 0.439
4.084ProGly: 4.084 ± 0.681
1.257ProHis: 1.257 ± 0.43
1.885ProIle: 1.885 ± 0.552
2.513ProLys: 2.513 ± 0.852
6.283ProLeu: 6.283 ± 0.624
0.314ProMet: 0.314 ± 0.162
1.885ProAsn: 1.885 ± 0.106
3.142ProPro: 3.142 ± 2.093
1.571ProGln: 1.571 ± 0.812
3.77ProArg: 3.77 ± 0.827
5.969ProSer: 5.969 ± 2.586
3.77ProThr: 3.77 ± 1.434
2.828ProVal: 2.828 ± 1.643
0.628ProTrp: 0.628 ± 0.325
2.199ProTyr: 2.199 ± 0.737
0.0ProXaa: 0.0 ± 0.0
Gln
2.828GlnAla: 2.828 ± 1.593
0.943GlnCys: 0.943 ± 0.487
1.257GlnAsp: 1.257 ± 0.43
2.199GlnGlu: 2.199 ± 0.606
2.828GlnPhe: 2.828 ± 1.001
2.513GlnGly: 2.513 ± 0.828
1.885GlnHis: 1.885 ± 0.552
3.456GlnIle: 3.456 ± 0.374
2.513GlnLys: 2.513 ± 0.852
4.398GlnLeu: 4.398 ± 0.118
1.571GlnMet: 1.571 ± 0.883
1.571GlnAsn: 1.571 ± 0.812
0.628GlnPro: 0.628 ± 0.419
1.257GlnGln: 1.257 ± 0.649
2.828GlnArg: 2.828 ± 0.382
2.513GlnSer: 2.513 ± 0.22
0.628GlnThr: 0.628 ± 1.048
2.513GlnVal: 2.513 ± 0.828
0.314GlnTrp: 0.314 ± 0.518
0.314GlnTyr: 0.314 ± 0.162
0.0GlnXaa: 0.0 ± 0.0
Arg
4.084ArgAla: 4.084 ± 1.333
0.943ArgCys: 0.943 ± 0.487
3.142ArgAsp: 3.142 ± 0.888
4.713ArgGlu: 4.713 ± 1.356
3.142ArgPhe: 3.142 ± 1.624
4.084ArgGly: 4.084 ± 0.055
1.257ArgHis: 1.257 ± 0.367
0.943ArgIle: 0.943 ± 0.487
1.885ArgLys: 1.885 ± 0.106
6.283ArgLeu: 6.283 ± 1.089
1.885ArgMet: 1.885 ± 1.259
1.257ArgAsn: 1.257 ± 0.649
2.828ArgPro: 2.828 ± 0.836
4.398ArgGln: 4.398 ± 1.194
4.084ArgArg: 4.084 ± 1.233
3.77ArgSer: 3.77 ± 2.122
3.77ArgThr: 3.77 ± 0.51
4.398ArgVal: 4.398 ± 1.196
0.628ArgTrp: 0.628 ± 0.325
0.943ArgTyr: 0.943 ± 0.487
0.0ArgXaa: 0.0 ± 0.0
Ser
3.77SerAla: 3.77 ± 0.869
1.571SerCys: 1.571 ± 0.463
3.142SerAsp: 3.142 ± 1.059
3.456SerGlu: 3.456 ± 0.984
3.456SerPhe: 3.456 ± 0.796
4.084SerGly: 4.084 ± 0.696
1.885SerHis: 1.885 ± 0.974
5.655SerIle: 5.655 ± 0.815
4.713SerLys: 4.713 ± 2.015
9.425SerLeu: 9.425 ± 2.187
1.571SerMet: 1.571 ± 1.144
2.199SerAsn: 2.199 ± 0.684
4.084SerPro: 4.084 ± 0.681
4.084SerGln: 4.084 ± 1.214
6.283SerArg: 6.283 ± 1.166
10.053SerSer: 10.053 ± 1.958
4.713SerThr: 4.713 ± 1.085
6.283SerVal: 6.283 ± 1.277
2.828SerTrp: 2.828 ± 0.977
2.199SerTyr: 2.199 ± 0.737
0.0SerXaa: 0.0 ± 0.0
Thr
3.142ThrAla: 3.142 ± 1.133
0.314ThrCys: 0.314 ± 0.162
3.142ThrAsp: 3.142 ± 0.544
5.969ThrGlu: 5.969 ± 1.233
3.456ThrPhe: 3.456 ± 0.374
3.456ThrGly: 3.456 ± 0.984
0.943ThrHis: 0.943 ± 0.369
3.142ThrIle: 3.142 ± 0.925
2.513ThrLys: 2.513 ± 1.12
6.598ThrLeu: 6.598 ± 1.412
2.199ThrMet: 2.199 ± 0.059
0.943ThrAsn: 0.943 ± 0.487
2.828ThrPro: 2.828 ± 1.593
1.571ThrGln: 1.571 ± 0.439
3.456ThrArg: 3.456 ± 0.984
7.226ThrSer: 7.226 ± 1.034
5.969ThrThr: 5.969 ± 1.104
6.598ThrVal: 6.598 ± 2.922
1.571ThrTrp: 1.571 ± 0.812
1.885ThrTyr: 1.885 ± 0.738
0.0ThrXaa: 0.0 ± 0.0
Val
4.398ValAla: 4.398 ± 3.81
1.257ValCys: 1.257 ± 0.649
4.713ValAsp: 4.713 ± 0.467
2.199ValGlu: 2.199 ± 0.598
4.713ValPhe: 4.713 ± 1.663
3.77ValGly: 3.77 ± 0.869
0.0ValHis: 0.0 ± 0.0
2.513ValIle: 2.513 ± 1.123
2.513ValLys: 2.513 ± 0.49
5.655ValLeu: 5.655 ± 1.337
0.628ValMet: 0.628 ± 0.303
2.828ValAsn: 2.828 ± 1.007
4.713ValPro: 4.713 ± 3.052
2.199ValGln: 2.199 ± 0.598
3.142ValArg: 3.142 ± 0.544
5.655ValSer: 5.655 ± 1.337
5.341ValThr: 5.341 ± 0.4
3.77ValVal: 3.77 ± 1.475
0.943ValTrp: 0.943 ± 0.487
0.628ValTyr: 0.628 ± 1.048
0.0ValXaa: 0.0 ± 0.0
Trp
0.314TrpAla: 0.314 ± 0.518
0.0TrpCys: 0.0 ± 0.0
0.314TrpAsp: 0.314 ± 0.162
1.257TrpGlu: 1.257 ± 0.649
0.943TrpPhe: 0.943 ± 0.487
0.943TrpGly: 0.943 ± 0.487
0.314TrpHis: 0.314 ± 0.162
1.571TrpIle: 1.571 ± 0.463
1.571TrpLys: 1.571 ± 0.463
1.571TrpLeu: 1.571 ± 0.463
0.0TrpMet: 0.0 ± 0.0
1.885TrpAsn: 1.885 ± 0.552
0.628TrpPro: 0.628 ± 0.325
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
1.257TrpSer: 1.257 ± 0.649
1.257TrpThr: 1.257 ± 0.649
0.943TrpVal: 0.943 ± 0.592
0.0TrpTrp: 0.0 ± 0.0
0.314TrpTyr: 0.314 ± 0.162
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.142TyrAla: 3.142 ± 0.925
0.314TyrCys: 0.314 ± 0.518
0.628TyrAsp: 0.628 ± 0.755
0.943TyrGlu: 0.943 ± 0.487
2.199TyrPhe: 2.199 ± 0.709
1.571TyrGly: 1.571 ± 0.268
0.314TyrHis: 0.314 ± 0.162
0.628TyrIle: 0.628 ± 0.42
1.257TyrLys: 1.257 ± 0.649
3.77TyrLeu: 3.77 ± 0.51
0.943TyrMet: 0.943 ± 0.369
0.943TyrAsn: 0.943 ± 0.487
1.257TyrPro: 1.257 ± 0.649
1.571TyrGln: 1.571 ± 0.812
2.513TyrArg: 2.513 ± 0.22
2.199TyrSer: 2.199 ± 1.137
1.571TyrThr: 1.571 ± 0.463
1.257TyrVal: 1.257 ± 0.386
0.314TyrTrp: 0.314 ± 0.162
0.943TyrTyr: 0.943 ± 0.369
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (3184 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski