Simian immunodeficiency virus - olc

Taxonomy: Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes; Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus; Simian immunodeficiency virus

Average proteome isoelectric point is 7.5

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 5 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|B7UES4|B7UES4_SIV Envelope glycoprotein gp160 OS=Simian immunodeficiency virus - olc OX=538563 GN=env PE=4 SV=1
MM1 pKa = 7.74AEE3 pKa = 4.88RR4 pKa = 11.84VPEE7 pKa = 4.22DD8 pKa = 3.04QGPPRR13 pKa = 11.84EE14 pKa = 4.11PLEE17 pKa = 4.08DD18 pKa = 3.17WVRR21 pKa = 11.84DD22 pKa = 3.6TMEE25 pKa = 4.56EE26 pKa = 3.94IIVEE30 pKa = 4.69AKK32 pKa = 9.93RR33 pKa = 11.84HH34 pKa = 5.15FPRR37 pKa = 11.84EE38 pKa = 3.54LLVRR42 pKa = 11.84VFLFCAQRR50 pKa = 11.84HH51 pKa = 5.76INDD54 pKa = 3.69EE55 pKa = 4.22MSTSLLFIRR64 pKa = 11.84LLQRR68 pKa = 11.84ALFQHH73 pKa = 5.86YY74 pKa = 10.37RR75 pKa = 11.84NGCPGVEE82 pKa = 4.26LRR84 pKa = 11.84RR85 pKa = 11.84NPHH88 pKa = 5.87RR89 pKa = 11.84RR90 pKa = 11.84SEE92 pKa = 4.12GMQEE96 pKa = 3.61

Molecular weight: 11.53 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|B7UES3|B7UES3_SIV Protein Vpr OS=Simian immunodeficiency virus - olc OX=538563 GN=vpr PE=4 SV=1
MM1 pKa = 7.26EE2 pKa = 5.71WIAVPMYY9 pKa = 10.29RR10 pKa = 11.84LNNGQVEE17 pKa = 4.6HH18 pKa = 6.25VKK20 pKa = 10.64FMAKK24 pKa = 10.08LAYY27 pKa = 9.52KK28 pKa = 9.9FWGYY32 pKa = 9.91HH33 pKa = 5.6WIWQNCYY40 pKa = 10.22KK41 pKa = 10.49YY42 pKa = 10.1PRR44 pKa = 11.84EE45 pKa = 3.83WWTHH49 pKa = 3.39GKK51 pKa = 9.86IYY53 pKa = 10.42IPVPGGEE60 pKa = 4.15IEE62 pKa = 4.06ITLYY66 pKa = 9.08WHH68 pKa = 6.36IRR70 pKa = 11.84HH71 pKa = 6.29GKK73 pKa = 8.95GLQNSGGVNFKK84 pKa = 10.93YY85 pKa = 10.29IVGISWMYY93 pKa = 7.89LTPEE97 pKa = 3.98YY98 pKa = 10.89VDD100 pKa = 4.93FMVHH104 pKa = 6.36LVYY107 pKa = 9.9FACWTQSAIRR117 pKa = 11.84KK118 pKa = 9.27AILGMPDD125 pKa = 2.86HH126 pKa = 7.49RR127 pKa = 11.84YY128 pKa = 8.81CQLEE132 pKa = 4.18TGHH135 pKa = 7.42LGVLSLQLLALRR147 pKa = 11.84AVRR150 pKa = 11.84NGRR153 pKa = 11.84KK154 pKa = 9.17SSRR157 pKa = 11.84GSGATQGATGGLGEE171 pKa = 4.2RR172 pKa = 11.84HH173 pKa = 6.2NGRR176 pKa = 11.84NYY178 pKa = 10.43CRR180 pKa = 11.84GKK182 pKa = 10.22KK183 pKa = 9.89ALSQGVIGPSFSILCSKK200 pKa = 9.25TYY202 pKa = 9.31QQ203 pKa = 3.17

Molecular weight: 23.32 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

5

0

5

2616

96

994

523.2

59.64

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.352 ± 0.357

2.37 ± 0.396

3.746 ± 0.411

7.913 ± 1.17

2.867 ± 0.173

7.951 ± 0.55

1.873 ± 0.419

6.193 ± 0.734

7.645 ± 0.778

8.945 ± 0.579

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.141 ± 0.291

4.32 ± 0.566

4.817 ± 0.454

5.887 ± 0.319

5.696 ± 0.471

4.358 ± 0.369

5.39 ± 0.915

6.613 ± 0.249

2.599 ± 0.327

3.326 ± 0.44
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski