Amino acid dipepetide frequency for Pusillimonas ginsengisoli

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.478AlaAla: 13.478 ± 0.128	1.267AlaCys: 1.267 ± 0.034	5.915AlaAsp: 5.915 ± 0.07	5.553AlaGlu: 5.553 ± 0.069	3.836AlaPhe: 3.836 ± 0.059	9.693AlaGly: 9.693 ± 0.124	2.42AlaHis: 2.42 ± 0.046	5.945AlaIle: 5.945 ± 0.07	3.362AlaLys: 3.362 ± 0.062	12.951AlaLeu: 12.951 ± 0.132	3.281AlaMet: 3.281 ± 0.056	2.993AlaAsn: 2.993 ± 0.051	4.619AlaPro: 4.619 ± 0.07	5.074AlaGln: 5.074 ± 0.07	7.206AlaArg: 7.206 ± 0.075	6.946AlaSer: 6.946 ± 0.075	5.815AlaThr: 5.815 ± 0.075	8.036AlaVal: 8.036 ± 0.085	1.676AlaTrp: 1.676 ± 0.042	2.659AlaTyr: 2.659 ± 0.039	0.0AlaXaa: 0.0 ± 0.0
Cys	1.09CysAla: 1.09 ± 0.031	0.15CysCys: 0.15 ± 0.01	0.523CysAsp: 0.523 ± 0.019	0.484CysGlu: 0.484 ± 0.021	0.358CysPhe: 0.358 ± 0.016	0.939CysGly: 0.939 ± 0.025	0.273CysHis: 0.273 ± 0.015	0.497CysIle: 0.497 ± 0.021	0.255CysLys: 0.255 ± 0.013	0.911CysLeu: 0.911 ± 0.028	0.27CysMet: 0.27 ± 0.015	0.278CysAsn: 0.278 ± 0.014	0.497CysPro: 0.497 ± 0.023	0.32CysGln: 0.32 ± 0.015	0.561CysArg: 0.561 ± 0.023	0.603CysSer: 0.603 ± 0.022	0.53CysThr: 0.53 ± 0.023	0.755CysVal: 0.755 ± 0.025	0.145CysTrp: 0.145 ± 0.012	0.211CysTyr: 0.211 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	6.024AspAla: 6.024 ± 0.063	0.485AspCys: 0.485 ± 0.018	2.913AspAsp: 2.913 ± 0.053	3.23AspGlu: 3.23 ± 0.055	1.94AspPhe: 1.94 ± 0.041	4.192AspGly: 4.192 ± 0.065	1.212AspHis: 1.212 ± 0.035	3.081AspIle: 3.081 ± 0.042	1.841AspLys: 1.841 ± 0.041	5.098AspLeu: 5.098 ± 0.067	1.452AspMet: 1.452 ± 0.034	1.471AspAsn: 1.471 ± 0.033	2.711AspPro: 2.711 ± 0.045	1.97AspGln: 1.97 ± 0.042	3.063AspArg: 3.063 ± 0.054	2.601AspSer: 2.601 ± 0.044	3.041AspThr: 3.041 ± 0.05	4.027AspVal: 4.027 ± 0.061	0.841AspTrp: 0.841 ± 0.027	1.626AspTyr: 1.626 ± 0.036	0.0AspXaa: 0.0 ± 0.0
Glu	5.868GluAla: 5.868 ± 0.072	0.414GluCys: 0.414 ± 0.016	2.279GluAsp: 2.279 ± 0.044	2.471GluGlu: 2.471 ± 0.05	1.742GluPhe: 1.742 ± 0.035	3.649GluGly: 3.649 ± 0.06	1.506GluHis: 1.506 ± 0.035	2.951GluIle: 2.951 ± 0.05	2.123GluLys: 2.123 ± 0.05	5.326GluLeu: 5.326 ± 0.088	1.287GluMet: 1.287 ± 0.033	1.726GluAsn: 1.726 ± 0.038	2.395GluPro: 2.395 ± 0.055	2.807GluGln: 2.807 ± 0.046	3.885GluArg: 3.885 ± 0.061	2.815GluSer: 2.815 ± 0.049	2.761GluThr: 2.761 ± 0.046	3.676GluVal: 3.676 ± 0.058	0.633GluTrp: 0.633 ± 0.024	1.223GluTyr: 1.223 ± 0.033	0.0GluXaa: 0.0 ± 0.0
Phe	3.73PheAla: 3.73 ± 0.055	0.407PheCys: 0.407 ± 0.018	2.452PheAsp: 2.452 ± 0.048	1.976PheGlu: 1.976 ± 0.042	1.454PhePhe: 1.454 ± 0.038	3.351PheGly: 3.351 ± 0.056	0.737PheHis: 0.737 ± 0.025	1.939PheIle: 1.939 ± 0.044	1.172PheLys: 1.172 ± 0.034	3.264PheLeu: 3.264 ± 0.054	0.933PheMet: 0.933 ± 0.027	1.238PheAsn: 1.238 ± 0.033	1.629PhePro: 1.629 ± 0.035	1.051PheGln: 1.051 ± 0.029	1.851PheArg: 1.851 ± 0.041	2.643PheSer: 2.643 ± 0.04	2.066PheThr: 2.066 ± 0.045	2.703PheVal: 2.703 ± 0.049	0.559PheTrp: 0.559 ± 0.026	1.052PheTyr: 1.052 ± 0.029	0.0PheXaa: 0.0 ± 0.0
Gly	8.084GlyAla: 8.084 ± 0.107	0.822GlyCys: 0.822 ± 0.027	3.757GlyAsp: 3.757 ± 0.061	4.032GlyGlu: 4.032 ± 0.054	3.207GlyPhe: 3.207 ± 0.052	6.343GlyGly: 6.343 ± 0.156	2.001GlyHis: 2.001 ± 0.045	4.697GlyIle: 4.697 ± 0.068	3.597GlyLys: 3.597 ± 0.057	8.92GlyLeu: 8.92 ± 0.085	2.561GlyMet: 2.561 ± 0.048	2.351GlyAsn: 2.351 ± 0.056	3.001GlyPro: 3.001 ± 0.05	3.332GlyGln: 3.332 ± 0.049	4.735GlyArg: 4.735 ± 0.056	4.945GlySer: 4.945 ± 0.089	4.453GlyThr: 4.453 ± 0.085	6.388GlyVal: 6.388 ± 0.077	1.334GlyTrp: 1.334 ± 0.032	2.466GlyTyr: 2.466 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	2.694HisAla: 2.694 ± 0.053	0.295HisCys: 0.295 ± 0.013	1.406HisAsp: 1.406 ± 0.032	1.289HisGlu: 1.289 ± 0.032	0.877HisPhe: 0.877 ± 0.027	2.047HisGly: 2.047 ± 0.042	0.642HisHis: 0.642 ± 0.022	1.256HisIle: 1.256 ± 0.025	0.693HisLys: 0.693 ± 0.021	2.091HisLeu: 2.091 ± 0.039	0.586HisMet: 0.586 ± 0.022	0.676HisAsn: 0.676 ± 0.024	1.382HisPro: 1.382 ± 0.033	0.873HisGln: 0.873 ± 0.024	1.32HisArg: 1.32 ± 0.034	1.252HisSer: 1.252 ± 0.03	1.27HisThr: 1.27 ± 0.028	1.673HisVal: 1.673 ± 0.033	0.373HisTrp: 0.373 ± 0.017	0.703HisTyr: 0.703 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	6.479IleAla: 6.479 ± 0.08	0.481IleCys: 0.481 ± 0.019	3.322IleAsp: 3.322 ± 0.053	3.338IleGlu: 3.338 ± 0.054	1.716IlePhe: 1.716 ± 0.041	4.516IleGly: 4.516 ± 0.072	1.054IleHis: 1.054 ± 0.028	2.738IleIle: 2.738 ± 0.051	2.012IleLys: 2.012 ± 0.038	4.469IleLeu: 4.469 ± 0.07	1.261IleMet: 1.261 ± 0.032	1.937IleAsn: 1.937 ± 0.039	2.478IlePro: 2.478 ± 0.044	1.728IleGln: 1.728 ± 0.038	2.873IleArg: 2.873 ± 0.043	3.385IleSer: 3.385 ± 0.05	3.144IleThr: 3.144 ± 0.051	4.209IleVal: 4.209 ± 0.06	0.655IleTrp: 0.655 ± 0.024	1.24IleTyr: 1.24 ± 0.035	0.0IleXaa: 0.0 ± 0.0
Lys	3.953LysAla: 3.953 ± 0.074	0.17LysCys: 0.17 ± 0.011	1.692LysAsp: 1.692 ± 0.039	1.785LysGlu: 1.785 ± 0.04	0.981LysPhe: 0.981 ± 0.03	2.589LysGly: 2.589 ± 0.049	0.791LysHis: 0.791 ± 0.022	1.751LysIle: 1.751 ± 0.039	1.585LysLys: 1.585 ± 0.049	3.447LysLeu: 3.447 ± 0.051	0.88LysMet: 0.88 ± 0.024	1.164LysAsn: 1.164 ± 0.029	2.081LysPro: 2.081 ± 0.047	1.438LysGln: 1.438 ± 0.031	2.273LysArg: 2.273 ± 0.044	2.048LysSer: 2.048 ± 0.044	2.184LysThr: 2.184 ± 0.048	2.435LysVal: 2.435 ± 0.045	0.47LysTrp: 0.47 ± 0.02	0.79LysTyr: 0.79 ± 0.027	0.0LysXaa: 0.0 ± 0.0
Leu	13.268LeuAla: 13.268 ± 0.126	1.076LeuCys: 1.076 ± 0.026	5.891LeuAsp: 5.891 ± 0.074	5.109LeuGlu: 5.109 ± 0.066	3.822LeuPhe: 3.822 ± 0.07	8.506LeuGly: 8.506 ± 0.074	2.342LeuHis: 2.342 ± 0.051	5.411LeuIle: 5.411 ± 0.078	3.59LeuLys: 3.59 ± 0.056	10.922LeuLeu: 10.922 ± 0.117	2.614LeuMet: 2.614 ± 0.048	3.208LeuAsn: 3.208 ± 0.056	5.641LeuPro: 5.641 ± 0.071	3.882LeuGln: 3.882 ± 0.058	6.761LeuArg: 6.761 ± 0.077	6.978LeuSer: 6.978 ± 0.069	5.795LeuThr: 5.795 ± 0.071	7.436LeuVal: 7.436 ± 0.076	1.186LeuTrp: 1.186 ± 0.036	2.389LeuTyr: 2.389 ± 0.046	0.0LeuXaa: 0.0 ± 0.0
Met	3.113MetAla: 3.113 ± 0.05	0.212MetCys: 0.212 ± 0.014	1.113MetAsp: 1.113 ± 0.03	1.021MetGlu: 1.021 ± 0.029	0.842MetPhe: 0.842 ± 0.029	2.06MetGly: 2.06 ± 0.039	0.605MetHis: 0.605 ± 0.022	1.262MetIle: 1.262 ± 0.036	1.086MetLys: 1.086 ± 0.031	3.12MetLeu: 3.12 ± 0.053	0.712MetMet: 0.712 ± 0.031	0.913MetAsn: 0.913 ± 0.025	1.554MetPro: 1.554 ± 0.039	1.211MetGln: 1.211 ± 0.033	1.738MetArg: 1.738 ± 0.038	1.874MetSer: 1.874 ± 0.035	1.652MetThr: 1.652 ± 0.034	1.9MetVal: 1.9 ± 0.04	0.223MetTrp: 0.223 ± 0.012	0.483MetTyr: 0.483 ± 0.021	0.0MetXaa: 0.0 ± 0.0
Asn	3.371AsnAla: 3.371 ± 0.053	0.271AsnCys: 0.271 ± 0.013	1.507AsnAsp: 1.507 ± 0.033	1.528AsnGlu: 1.528 ± 0.034	1.082AsnPhe: 1.082 ± 0.029	2.442AsnGly: 2.442 ± 0.047	0.621AsnHis: 0.621 ± 0.021	1.723AsnIle: 1.723 ± 0.038	1.071AsnLys: 1.071 ± 0.035	2.954AsnLeu: 2.954 ± 0.044	0.799AsnMet: 0.799 ± 0.025	1.038AsnAsn: 1.038 ± 0.029	1.887AsnPro: 1.887 ± 0.04	1.111AsnGln: 1.111 ± 0.03	1.759AsnArg: 1.759 ± 0.037	1.591AsnSer: 1.591 ± 0.036	1.81AsnThr: 1.81 ± 0.052	2.245AsnVal: 2.245 ± 0.046	0.502AsnTrp: 0.502 ± 0.019	0.806AsnTyr: 0.806 ± 0.023	0.0AsnXaa: 0.0 ± 0.0
Pro	5.46ProAla: 5.46 ± 0.078	0.364ProCys: 0.364 ± 0.017	3.384ProAsp: 3.384 ± 0.055	3.416ProGlu: 3.416 ± 0.057	1.765ProPhe: 1.765 ± 0.039	4.17ProGly: 4.17 ± 0.059	1.114ProHis: 1.114 ± 0.031	2.225ProIle: 2.225 ± 0.038	1.471ProLys: 1.471 ± 0.036	4.761ProLeu: 4.761 ± 0.073	1.288ProMet: 1.288 ± 0.028	1.331ProAsn: 1.331 ± 0.034	2.097ProPro: 2.097 ± 0.044	1.876ProGln: 1.876 ± 0.041	2.457ProArg: 2.457 ± 0.051	2.919ProSer: 2.919 ± 0.048	2.473ProThr: 2.473 ± 0.039	4.182ProVal: 4.182 ± 0.06	0.735ProTrp: 0.735 ± 0.026	1.267ProTyr: 1.267 ± 0.028	0.0ProXaa: 0.0 ± 0.0
Gln	5.499GlnAla: 5.499 ± 0.072	0.346GlnCys: 0.346 ± 0.016	1.722GlnAsp: 1.722 ± 0.039	1.814GlnGlu: 1.814 ± 0.041	1.326GlnPhe: 1.326 ± 0.032	3.198GlnGly: 3.198 ± 0.051	1.076GlnHis: 1.076 ± 0.028	2.116GlnIle: 2.116 ± 0.045	1.362GlnLys: 1.362 ± 0.037	4.179GlnLeu: 4.179 ± 0.065	1.001GlnMet: 1.001 ± 0.027	1.135GlnAsn: 1.135 ± 0.027	2.092GlnPro: 2.092 ± 0.04	2.108GlnGln: 2.108 ± 0.044	2.97GlnArg: 2.97 ± 0.054	2.295GlnSer: 2.295 ± 0.042	2.206GlnThr: 2.206 ± 0.039	2.834GlnVal: 2.834 ± 0.05	0.65GlnTrp: 0.65 ± 0.024	0.958GlnTyr: 0.958 ± 0.027	0.0GlnXaa: 0.0 ± 0.0
Arg	6.013ArgAla: 6.013 ± 0.081	0.595ArgCys: 0.595 ± 0.024	3.206ArgAsp: 3.206 ± 0.06	3.466ArgGlu: 3.466 ± 0.054	2.462ArgPhe: 2.462 ± 0.047	4.005ArgGly: 4.005 ± 0.053	1.771ArgHis: 1.771 ± 0.035	3.569ArgIle: 3.569 ± 0.057	2.198ArgLys: 2.198 ± 0.043	7.178ArgLeu: 7.178 ± 0.079	1.775ArgMet: 1.775 ± 0.041	2.007ArgAsn: 2.007 ± 0.041	2.727ArgPro: 2.727 ± 0.044	3.044ArgGln: 3.044 ± 0.056	4.448ArgArg: 4.448 ± 0.072	3.51ArgSer: 3.51 ± 0.052	2.991ArgThr: 2.991 ± 0.04	4.541ArgVal: 4.541 ± 0.066	0.959ArgTrp: 0.959 ± 0.031	1.929ArgTyr: 1.929 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	6.505SerAla: 6.505 ± 0.09	0.534SerCys: 0.534 ± 0.024	3.12SerAsp: 3.12 ± 0.05	2.93SerGlu: 2.93 ± 0.048	2.339SerPhe: 2.339 ± 0.043	5.745SerGly: 5.745 ± 0.085	1.357SerHis: 1.357 ± 0.033	3.153SerIle: 3.153 ± 0.048	1.878SerLys: 1.878 ± 0.041	6.565SerLeu: 6.565 ± 0.074	1.711SerMet: 1.711 ± 0.036	1.771SerAsn: 1.771 ± 0.041	2.938SerPro: 2.938 ± 0.049	2.304SerGln: 2.304 ± 0.041	3.767SerArg: 3.767 ± 0.057	3.981SerSer: 3.981 ± 0.064	3.422SerThr: 3.422 ± 0.049	4.549SerVal: 4.549 ± 0.064	0.908SerTrp: 0.908 ± 0.027	1.56SerTyr: 1.56 ± 0.038	0.0SerXaa: 0.0 ± 0.0
Thr	5.731ThrAla: 5.731 ± 0.079	0.488ThrCys: 0.488 ± 0.021	2.743ThrAsp: 2.743 ± 0.051	2.585ThrGlu: 2.585 ± 0.044	1.781ThrPhe: 1.781 ± 0.042	4.991ThrGly: 4.991 ± 0.073	1.376ThrHis: 1.376 ± 0.033	2.791ThrIle: 2.791 ± 0.053	1.382ThrLys: 1.382 ± 0.037	6.723ThrLeu: 6.723 ± 0.085	1.328ThrMet: 1.328 ± 0.029	1.432ThrAsn: 1.432 ± 0.034	3.442ThrPro: 3.442 ± 0.061	2.107ThrGln: 2.107 ± 0.042	3.263ThrArg: 3.263 ± 0.048	3.257ThrSer: 3.257 ± 0.055	3.041ThrThr: 3.041 ± 0.057	4.399ThrVal: 4.399 ± 0.06	0.734ThrTrp: 0.734 ± 0.025	1.229ThrTyr: 1.229 ± 0.032	0.0ThrXaa: 0.0 ± 0.0
Val	8.394ValAla: 8.394 ± 0.08	0.814ValCys: 0.814 ± 0.026	3.863ValAsp: 3.863 ± 0.06	3.697ValGlu: 3.697 ± 0.061	3.07ValPhe: 3.07 ± 0.048	5.425ValGly: 5.425 ± 0.073	1.566ValHis: 1.566 ± 0.031	4.117ValIle: 4.117 ± 0.06	2.488ValLys: 2.488 ± 0.054	8.263ValLeu: 8.263 ± 0.095	1.954ValMet: 1.954 ± 0.039	2.281ValAsn: 2.281 ± 0.048	3.682ValPro: 3.682 ± 0.055	2.86ValGln: 2.86 ± 0.046	4.577ValArg: 4.577 ± 0.066	5.047ValSer: 5.047 ± 0.068	4.09ValThr: 4.09 ± 0.06	5.955ValVal: 5.955 ± 0.074	1.004ValTrp: 1.004 ± 0.034	1.758ValTyr: 1.758 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	1.266TrpAla: 1.266 ± 0.03	0.154TrpCys: 0.154 ± 0.01	0.601TrpAsp: 0.601 ± 0.021	0.526TrpGlu: 0.526 ± 0.021	0.574TrpPhe: 0.574 ± 0.023	0.94TrpGly: 0.94 ± 0.029	0.404TrpHis: 0.404 ± 0.017	0.698TrpIle: 0.698 ± 0.025	0.477TrpLys: 0.477 ± 0.021	2.087TrpLeu: 2.087 ± 0.052	0.414TrpMet: 0.414 ± 0.017	0.458TrpAsn: 0.458 ± 0.02	0.632TrpPro: 0.632 ± 0.022	0.771TrpGln: 0.771 ± 0.027	1.108TrpArg: 1.108 ± 0.032	0.868TrpSer: 0.868 ± 0.029	0.649TrpThr: 0.649 ± 0.025	1.059TrpVal: 1.059 ± 0.033	0.247TrpTrp: 0.247 ± 0.015	0.33TrpTyr: 0.33 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.704TyrAla: 2.704 ± 0.048	0.306TyrCys: 0.306 ± 0.014	1.412TyrAsp: 1.412 ± 0.032	1.288TyrGlu: 1.288 ± 0.032	1.033TyrPhe: 1.033 ± 0.026	2.222TyrGly: 2.222 ± 0.044	0.528TyrHis: 0.528 ± 0.019	1.115TyrIle: 1.115 ± 0.03	0.861TyrLys: 0.861 ± 0.023	2.596TyrLeu: 2.596 ± 0.044	0.586TyrMet: 0.586 ± 0.021	0.711TyrAsn: 0.711 ± 0.026	1.271TyrPro: 1.271 ± 0.028	1.022TyrGln: 1.022 ± 0.028	1.781TyrArg: 1.781 ± 0.037	1.481TyrSer: 1.481 ± 0.035	1.432TyrThr: 1.432 ± 0.035	1.904TyrVal: 1.904 ± 0.035	0.43TyrTrp: 0.43 ± 0.021	0.71TyrTyr: 0.71 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4096 proteins (1320091 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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