Amino acid dipepetide frequency for Odocoileus virginianus texanus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.928AlaAla: 6.928 ± 0.034
1.393AlaCys: 1.393 ± 0.009
2.965AlaAsp: 2.965 ± 0.013
4.968AlaGlu: 4.968 ± 0.026
2.592AlaPhe: 2.592 ± 0.013
4.688AlaGly: 4.688 ± 0.023
1.582AlaHis: 1.582 ± 0.01
2.672AlaIle: 2.672 ± 0.013
3.361AlaLys: 3.361 ± 0.017
7.21AlaLeu: 7.21 ± 0.027
1.464AlaMet: 1.464 ± 0.009
1.969AlaAsn: 1.969 ± 0.011
4.436AlaPro: 4.436 ± 0.028
3.402AlaGln: 3.402 ± 0.019
3.792AlaArg: 3.792 ± 0.016
6.05AlaSer: 6.05 ± 0.024
3.495AlaThr: 3.495 ± 0.018
4.746AlaVal: 4.746 ± 0.018
0.781AlaTrp: 0.781 ± 0.008
1.485AlaTyr: 1.485 ± 0.008
0.005AlaXaa: 0.005 ± 0.0
Cys
1.228CysAla: 1.228 ± 0.01
0.604CysCys: 0.604 ± 0.009
0.984CysAsp: 0.984 ± 0.009
1.203CysGlu: 1.203 ± 0.009
0.83CysPhe: 0.83 ± 0.006
1.678CysGly: 1.678 ± 0.015
0.626CysHis: 0.626 ± 0.006
0.897CysIle: 0.897 ± 0.008
1.083CysLys: 1.083 ± 0.008
2.097CysLeu: 2.097 ± 0.012
0.397CysMet: 0.397 ± 0.004
0.741CysAsn: 0.741 ± 0.007
1.308CysPro: 1.308 ± 0.013
1.019CysGln: 1.019 ± 0.008
1.264CysArg: 1.264 ± 0.008
1.951CysSer: 1.951 ± 0.012
1.015CysThr: 1.015 ± 0.008
1.247CysVal: 1.247 ± 0.01
0.278CysTrp: 0.278 ± 0.004
0.555CysTyr: 0.555 ± 0.005
0.002CysXaa: 0.002 ± 0.0
Asp
2.902AspAla: 2.902 ± 0.013
1.0AspCys: 1.0 ± 0.008
2.654AspAsp: 2.654 ± 0.017
3.44AspGlu: 3.44 ± 0.016
2.067AspPhe: 2.067 ± 0.011
3.201AspGly: 3.201 ± 0.017
1.131AspHis: 1.131 ± 0.008
2.468AspIle: 2.468 ± 0.012
2.497AspLys: 2.497 ± 0.013
5.005AspLeu: 5.005 ± 0.019
1.099AspMet: 1.099 ± 0.008
1.58AspAsn: 1.58 ± 0.01
2.992AspPro: 2.992 ± 0.017
1.847AspGln: 1.847 ± 0.01
2.488AspArg: 2.488 ± 0.014
4.307AspSer: 4.307 ± 0.019
2.447AspThr: 2.447 ± 0.013
3.029AspVal: 3.029 ± 0.017
0.601AspTrp: 0.601 ± 0.006
1.423AspTyr: 1.423 ± 0.008
0.004AspXaa: 0.004 ± 0.0
Glu
5.409GluAla: 5.409 ± 0.023
1.357GluCys: 1.357 ± 0.016
4.477GluAsp: 4.477 ± 0.016
8.178GluGlu: 8.178 ± 0.046
2.026GluPhe: 2.026 ± 0.01
4.193GluGly: 4.193 ± 0.018
1.495GluHis: 1.495 ± 0.009
3.078GluIle: 3.078 ± 0.017
5.568GluLys: 5.568 ± 0.03
6.543GluLeu: 6.543 ± 0.031
1.694GluMet: 1.694 ± 0.01
3.076GluAsn: 3.076 ± 0.016
3.385GluPro: 3.385 ± 0.018
3.279GluGln: 3.279 ± 0.018
4.254GluArg: 4.254 ± 0.023
4.601GluSer: 4.601 ± 0.019
3.477GluThr: 3.477 ± 0.017
4.197GluVal: 4.197 ± 0.021
0.663GluTrp: 0.663 ± 0.006
1.503GluTyr: 1.503 ± 0.011
0.004GluXaa: 0.004 ± 0.0
Phe
1.882PheAla: 1.882 ± 0.009
0.93PheCys: 0.93 ± 0.008
1.611PheAsp: 1.611 ± 0.009
1.945PheGlu: 1.945 ± 0.01
1.593PhePhe: 1.593 ± 0.01
2.129PheGly: 2.129 ± 0.013
1.012PheHis: 1.012 ± 0.007
1.798PheIle: 1.798 ± 0.012
1.71PheLys: 1.71 ± 0.01
4.047PheLeu: 4.047 ± 0.018
0.751PheMet: 0.751 ± 0.007
1.277PheAsn: 1.277 ± 0.008
2.043PhePro: 2.043 ± 0.011
1.77PheGln: 1.77 ± 0.01
1.943PheArg: 1.943 ± 0.012
3.414PheSer: 3.414 ± 0.014
1.958PheThr: 1.958 ± 0.011
2.076PheVal: 2.076 ± 0.011
0.467PheTrp: 0.467 ± 0.004
1.146PheTyr: 1.146 ± 0.008
0.003PheXaa: 0.003 ± 0.0
Gly
4.516GlyAla: 4.516 ± 0.023
1.214GlyCys: 1.214 ± 0.008
3.063GlyAsp: 3.063 ± 0.016
4.067GlyGlu: 4.067 ± 0.022
2.285GlyPhe: 2.285 ± 0.013
4.923GlyGly: 4.923 ± 0.03
1.662GlyHis: 1.662 ± 0.011
2.559GlyIle: 2.559 ± 0.013
3.678GlyLys: 3.678 ± 0.02
5.865GlyLeu: 5.865 ± 0.023
1.282GlyMet: 1.282 ± 0.008
2.279GlyAsn: 2.279 ± 0.012
4.416GlyPro: 4.416 ± 0.036
2.809GlyGln: 2.809 ± 0.015
3.869GlyArg: 3.869 ± 0.018
5.942GlySer: 5.942 ± 0.026
3.462GlyThr: 3.462 ± 0.016
3.476GlyVal: 3.476 ± 0.017
0.751GlyTrp: 0.751 ± 0.008
1.597GlyTyr: 1.597 ± 0.011
0.006GlyXaa: 0.006 ± 0.001
His
1.329HisAla: 1.329 ± 0.009
0.665HisCys: 0.665 ± 0.006
0.871HisAsp: 0.871 ± 0.007
1.293HisGlu: 1.293 ± 0.008
1.068HisPhe: 1.068 ± 0.008
1.515HisGly: 1.515 ± 0.011
0.901HisHis: 0.901 ± 0.011
1.183HisIle: 1.183 ± 0.007
1.26HisLys: 1.26 ± 0.008
2.933HisLeu: 2.933 ± 0.015
0.569HisMet: 0.569 ± 0.005
0.808HisAsn: 0.808 ± 0.007
1.712HisPro: 1.712 ± 0.012
1.406HisGln: 1.406 ± 0.013
1.62HisArg: 1.62 ± 0.012
2.344HisSer: 2.344 ± 0.013
1.52HisThr: 1.52 ± 0.014
1.496HisVal: 1.496 ± 0.008
0.334HisTrp: 0.334 ± 0.004
0.781HisTyr: 0.781 ± 0.006
0.002HisXaa: 0.002 ± 0.0
Ile
2.452IleAla: 2.452 ± 0.013
1.027IleCys: 1.027 ± 0.008
1.934IleAsp: 1.934 ± 0.011
2.507IleGlu: 2.507 ± 0.014
1.838IlePhe: 1.838 ± 0.012
2.043IleGly: 2.043 ± 0.012
1.316IleHis: 1.316 ± 0.01
2.266IleIle: 2.266 ± 0.015
2.546IleLys: 2.546 ± 0.014
4.45IleLeu: 4.45 ± 0.02
0.965IleMet: 0.965 ± 0.007
1.714IleAsn: 1.714 ± 0.01
2.567IlePro: 2.567 ± 0.013
2.27IleGln: 2.27 ± 0.013
2.311IleArg: 2.311 ± 0.011
3.675IleSer: 3.675 ± 0.017
2.487IleThr: 2.487 ± 0.014
2.352IleVal: 2.352 ± 0.013
0.481IleTrp: 0.481 ± 0.005
1.315IleTyr: 1.315 ± 0.009
0.002IleXaa: 0.002 ± 0.0
Lys
4.074LysAla: 4.074 ± 0.02
1.093LysCys: 1.093 ± 0.01
3.155LysAsp: 3.155 ± 0.018
5.255LysGlu: 5.255 ± 0.026
1.654LysPhe: 1.654 ± 0.01
3.145LysGly: 3.145 ± 0.021
1.382LysHis: 1.382 ± 0.01
2.675LysIle: 2.675 ± 0.017
4.739LysLys: 4.739 ± 0.027
5.161LysLeu: 5.161 ± 0.022
1.469LysMet: 1.469 ± 0.01
2.339LysAsn: 2.339 ± 0.014
3.207LysPro: 3.207 ± 0.021
2.673LysGln: 2.673 ± 0.015
3.372LysArg: 3.372 ± 0.015
3.977LysSer: 3.977 ± 0.017
3.124LysThr: 3.124 ± 0.015
3.394LysVal: 3.394 ± 0.016
0.581LysTrp: 0.581 ± 0.005
1.48LysTyr: 1.48 ± 0.01
0.003LysXaa: 0.003 ± 0.0
Leu
6.826LeuAla: 6.826 ± 0.026
2.118LeuCys: 2.118 ± 0.013
4.698LeuAsp: 4.698 ± 0.019
7.31LeuGlu: 7.31 ± 0.037
3.32LeuPhe: 3.32 ± 0.018
5.853LeuGly: 5.853 ± 0.022
2.691LeuHis: 2.691 ± 0.013
3.807LeuIle: 3.807 ± 0.017
5.808LeuLys: 5.808 ± 0.027
10.767LeuLeu: 10.767 ± 0.044
2.009LeuMet: 2.009 ± 0.01
3.465LeuAsn: 3.465 ± 0.014
6.168LeuPro: 6.168 ± 0.024
5.936LeuGln: 5.936 ± 0.03
6.06LeuArg: 6.06 ± 0.025
8.161LeuSer: 8.161 ± 0.023
5.112LeuThr: 5.112 ± 0.017
5.445LeuVal: 5.445 ± 0.02
1.114LeuTrp: 1.114 ± 0.008
2.447LeuTyr: 2.447 ± 0.012
0.006LeuXaa: 0.006 ± 0.001
Met
1.861MetAla: 1.861 ± 0.009
0.377MetCys: 0.377 ± 0.005
1.238MetAsp: 1.238 ± 0.007
1.875MetGlu: 1.875 ± 0.011
0.711MetPhe: 0.711 ± 0.006
1.265MetGly: 1.265 ± 0.01
0.455MetHis: 0.455 ± 0.004
0.838MetIle: 0.838 ± 0.006
1.45MetLys: 1.45 ± 0.009
1.978MetLeu: 1.978 ± 0.011
0.57MetMet: 0.57 ± 0.006
0.891MetAsn: 0.891 ± 0.007
1.094MetPro: 1.094 ± 0.009
0.948MetGln: 0.948 ± 0.007
1.033MetArg: 1.033 ± 0.007
1.578MetSer: 1.578 ± 0.008
1.117MetThr: 1.117 ± 0.008
1.356MetVal: 1.356 ± 0.008
0.235MetTrp: 0.235 ± 0.003
0.596MetTyr: 0.596 ± 0.006
0.001MetXaa: 0.001 ± 0.0
Asn
1.969AsnAla: 1.969 ± 0.009
0.785AsnCys: 0.785 ± 0.008
1.458AsnAsp: 1.458 ± 0.009
2.142AsnGlu: 2.142 ± 0.012
1.41AsnPhe: 1.41 ± 0.009
2.256AsnGly: 2.256 ± 0.013
0.929AsnHis: 0.929 ± 0.008
1.998AsnIle: 1.998 ± 0.012
2.175AsnLys: 2.175 ± 0.012
3.658AsnLeu: 3.658 ± 0.016
0.878AsnMet: 0.878 ± 0.007
1.441AsnAsn: 1.441 ± 0.012
2.177AsnPro: 2.177 ± 0.012
1.677AsnGln: 1.677 ± 0.012
1.817AsnArg: 1.817 ± 0.01
3.176AsnSer: 3.176 ± 0.015
1.922AsnThr: 1.922 ± 0.012
2.075AsnVal: 2.075 ± 0.01
0.43AsnTrp: 0.43 ± 0.004
1.047AsnTyr: 1.047 ± 0.009
0.002AsnXaa: 0.002 ± 0.0
Pro
5.26ProAla: 5.26 ± 0.029
1.096ProCys: 1.096 ± 0.01
2.799ProAsp: 2.799 ± 0.013
4.622ProGlu: 4.622 ± 0.022
1.932ProPhe: 1.932 ± 0.011
5.456ProGly: 5.456 ± 0.05
1.492ProHis: 1.492 ± 0.01
1.81ProIle: 1.81 ± 0.011
2.882ProLys: 2.882 ± 0.019
5.435ProLeu: 5.435 ± 0.023
1.099ProMet: 1.099 ± 0.008
1.781ProAsn: 1.781 ± 0.011
6.456ProPro: 6.456 ± 0.046
3.027ProGln: 3.027 ± 0.021
3.586ProArg: 3.586 ± 0.022
6.143ProSer: 6.143 ± 0.031
3.16ProThr: 3.16 ± 0.019
3.966ProVal: 3.966 ± 0.019
0.694ProTrp: 0.694 ± 0.007
1.499ProTyr: 1.499 ± 0.014
0.007ProXaa: 0.007 ± 0.001
Gln
3.658GlnAla: 3.658 ± 0.019
0.874GlnCys: 0.874 ± 0.008
2.35GlnAsp: 2.35 ± 0.013
4.09GlnGlu: 4.09 ± 0.025
1.358GlnPhe: 1.358 ± 0.009
2.885GlnGly: 2.885 ± 0.017
1.323GlnHis: 1.323 ± 0.01
1.968GlnIle: 1.968 ± 0.01
3.067GlnLys: 3.067 ± 0.016
4.853GlnLeu: 4.853 ± 0.024
1.147GlnMet: 1.147 ± 0.008
1.844GlnAsn: 1.844 ± 0.011
2.998GlnPro: 2.998 ± 0.02
3.234GlnGln: 3.234 ± 0.029
3.161GlnArg: 3.161 ± 0.019
3.276GlnSer: 3.276 ± 0.017
2.419GlnThr: 2.419 ± 0.013
2.829GlnVal: 2.829 ± 0.014
0.531GlnTrp: 0.531 ± 0.005
1.129GlnTyr: 1.129 ± 0.007
0.003GlnXaa: 0.003 ± 0.0
Arg
3.983ArgAla: 3.983 ± 0.018
1.163ArgCys: 1.163 ± 0.01
2.784ArgAsp: 2.784 ± 0.014
4.251ArgGlu: 4.251 ± 0.022
1.832ArgPhe: 1.832 ± 0.01
3.695ArgGly: 3.695 ± 0.021
1.556ArgHis: 1.556 ± 0.01
2.362ArgIle: 2.362 ± 0.014
3.796ArgLys: 3.796 ± 0.014
5.575ArgLeu: 5.575 ± 0.023
1.216ArgMet: 1.216 ± 0.009
2.106ArgAsn: 2.106 ± 0.011
3.463ArgPro: 3.463 ± 0.02
2.731ArgGln: 2.731 ± 0.016
4.587ArgArg: 4.587 ± 0.029
4.562ArgSer: 4.562 ± 0.028
2.889ArgThr: 2.889 ± 0.015
3.187ArgVal: 3.187 ± 0.016
0.671ArgTrp: 0.671 ± 0.006
1.416ArgTyr: 1.416 ± 0.009
0.004ArgXaa: 0.004 ± 0.001
Ser
5.605SerAla: 5.605 ± 0.021
1.798SerCys: 1.798 ± 0.012
3.94SerAsp: 3.94 ± 0.017
5.495SerGlu: 5.495 ± 0.021
3.034SerPhe: 3.034 ± 0.014
5.689SerGly: 5.689 ± 0.023
2.176SerHis: 2.176 ± 0.012
3.196SerIle: 3.196 ± 0.013
4.187SerLys: 4.187 ± 0.019
8.438SerLeu: 8.438 ± 0.024
1.607SerMet: 1.607 ± 0.009
2.684SerAsn: 2.684 ± 0.015
6.443SerPro: 6.443 ± 0.033
4.115SerGln: 4.115 ± 0.017
4.82SerArg: 4.82 ± 0.023
10.024SerSer: 10.024 ± 0.047
4.611SerThr: 4.611 ± 0.024
4.989SerVal: 4.989 ± 0.017
1.067SerTrp: 1.067 ± 0.008
2.054SerTyr: 2.054 ± 0.012
0.005SerXaa: 0.005 ± 0.001
Thr
3.784ThrAla: 3.784 ± 0.018
1.221ThrCys: 1.221 ± 0.01
2.455ThrAsp: 2.455 ± 0.012
3.547ThrGlu: 3.547 ± 0.018
2.017ThrPhe: 2.017 ± 0.011
3.505ThrGly: 3.505 ± 0.02
1.307ThrHis: 1.307 ± 0.011
2.276ThrIle: 2.276 ± 0.014
2.576ThrLys: 2.576 ± 0.014
5.253ThrLeu: 5.253 ± 0.017
1.082ThrMet: 1.082 ± 0.008
1.667ThrAsn: 1.667 ± 0.01
3.795ThrPro: 3.795 ± 0.02
2.355ThrGln: 2.355 ± 0.013
2.51ThrArg: 2.51 ± 0.011
4.8ThrSer: 4.8 ± 0.031
3.003ThrThr: 3.003 ± 0.031
3.85ThrVal: 3.85 ± 0.018
0.667ThrTrp: 0.667 ± 0.007
1.369ThrTyr: 1.369 ± 0.008
0.004ThrXaa: 0.004 ± 0.0
Val
4.202ValAla: 4.202 ± 0.016
1.405ValCys: 1.405 ± 0.009
2.893ValAsp: 2.893 ± 0.014
3.824ValGlu: 3.824 ± 0.019
2.341ValPhe: 2.341 ± 0.011
3.278ValGly: 3.278 ± 0.015
1.559ValHis: 1.559 ± 0.01
2.841ValIle: 2.841 ± 0.013
3.366ValLys: 3.366 ± 0.017
6.138ValLeu: 6.138 ± 0.021
1.304ValMet: 1.304 ± 0.008
2.204ValAsn: 2.204 ± 0.014
3.751ValPro: 3.751 ± 0.02
2.754ValGln: 2.754 ± 0.015
3.052ValArg: 3.052 ± 0.013
4.971ValSer: 4.971 ± 0.019
3.741ValThr: 3.741 ± 0.022
3.887ValVal: 3.887 ± 0.014
0.683ValTrp: 0.683 ± 0.006
1.573ValTyr: 1.573 ± 0.011
0.003ValXaa: 0.003 ± 0.0
Trp
0.763TrpAla: 0.763 ± 0.007
0.236TrpCys: 0.236 ± 0.004
0.636TrpAsp: 0.636 ± 0.007
0.793TrpGlu: 0.793 ± 0.007
0.42TrpPhe: 0.42 ± 0.005
0.718TrpGly: 0.718 ± 0.009
0.291TrpHis: 0.291 ± 0.004
0.516TrpIle: 0.516 ± 0.006
0.792TrpLys: 0.792 ± 0.007
1.158TrpLeu: 1.158 ± 0.01
0.299TrpMet: 0.299 ± 0.004
0.519TrpAsn: 0.519 ± 0.005
0.517TrpPro: 0.517 ± 0.005
0.508TrpGln: 0.508 ± 0.005
0.732TrpArg: 0.732 ± 0.006
0.849TrpSer: 0.849 ± 0.007
0.644TrpThr: 0.644 ± 0.008
0.662TrpVal: 0.662 ± 0.005
0.178TrpTrp: 0.178 ± 0.003
0.311TrpTyr: 0.311 ± 0.004
0.001TrpXaa: 0.001 ± 0.0
Tyr
1.348TyrAla: 1.348 ± 0.01
0.65TyrCys: 0.65 ± 0.006
1.212TyrAsp: 1.212 ± 0.009
1.646TyrGlu: 1.646 ± 0.011
1.176TyrPhe: 1.176 ± 0.008
1.599TyrGly: 1.599 ± 0.011
0.72TyrHis: 0.72 ± 0.007
1.308TyrIle: 1.308 ± 0.008
1.41TyrLys: 1.41 ± 0.011
2.552TyrLeu: 2.552 ± 0.012
0.567TyrMet: 0.567 ± 0.005
1.035TyrAsn: 1.035 ± 0.007
1.27TyrPro: 1.27 ± 0.01
1.233TyrGln: 1.233 ± 0.009
1.555TyrArg: 1.555 ± 0.009
2.169TyrSer: 2.169 ± 0.012
1.438TyrThr: 1.438 ± 0.008
1.503TyrVal: 1.503 ± 0.009
0.335TyrTrp: 0.335 ± 0.004
0.894TyrTyr: 0.894 ± 0.007
0.001TyrXaa: 0.001 ± 0.0
Xaa
0.005XaaAla: 0.005 ± 0.001
0.002XaaCys: 0.002 ± 0.0
0.003XaaAsp: 0.003 ± 0.0
0.004XaaGlu: 0.004 ± 0.0
0.003XaaPhe: 0.003 ± 0.0
0.006XaaGly: 0.006 ± 0.001
0.002XaaHis: 0.002 ± 0.0
0.002XaaIle: 0.002 ± 0.0
0.004XaaLys: 0.004 ± 0.0
0.006XaaLeu: 0.006 ± 0.001
0.001XaaMet: 0.001 ± 0.0
0.002XaaAsn: 0.002 ± 0.0
0.006XaaPro: 0.006 ± 0.0
0.002XaaGln: 0.002 ± 0.0
0.005XaaArg: 0.005 ± 0.001
0.005XaaSer: 0.005 ± 0.0
0.003XaaThr: 0.003 ± 0.0
0.004XaaVal: 0.004 ± 0.0
0.001XaaTrp: 0.001 ± 0.0
0.002XaaTyr: 0.002 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 37241 proteins (22674040 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski