Amino acid dipepetide frequency for Salmon isavirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.677AlaAla: 3.677 ± 1.128
1.149AlaCys: 1.149 ± 0.627
2.988AlaAsp: 2.988 ± 0.883
2.528AlaGlu: 2.528 ± 0.761
3.447AlaPhe: 3.447 ± 0.853
3.218AlaGly: 3.218 ± 0.833
0.0AlaHis: 0.0 ± 0.0
3.677AlaIle: 3.677 ± 1.058
3.447AlaLys: 3.447 ± 1.001
5.746AlaLeu: 5.746 ± 1.024
2.988AlaMet: 2.988 ± 0.716
2.528AlaAsn: 2.528 ± 0.818
2.068AlaPro: 2.068 ± 0.475
1.149AlaGln: 1.149 ± 0.463
3.218AlaArg: 3.218 ± 0.471
4.826AlaSer: 4.826 ± 0.647
4.367AlaThr: 4.367 ± 0.925
3.677AlaVal: 3.677 ± 0.974
0.689AlaTrp: 0.689 ± 0.417
0.919AlaTyr: 0.919 ± 0.542
0.0AlaXaa: 0.0 ± 0.0
Cys
0.46CysAla: 0.46 ± 0.257
0.919CysCys: 0.919 ± 0.452
1.149CysAsp: 1.149 ± 0.48
1.149CysGlu: 1.149 ± 0.474
1.149CysPhe: 1.149 ± 0.413
1.839CysGly: 1.839 ± 0.809
0.46CysHis: 0.46 ± 0.278
1.379CysIle: 1.379 ± 0.591
0.919CysLys: 0.919 ± 0.511
1.609CysLeu: 1.609 ± 0.581
0.919CysMet: 0.919 ± 0.321
0.689CysAsn: 0.689 ± 0.406
2.068CysPro: 2.068 ± 0.741
0.23CysGln: 0.23 ± 0.272
2.758CysArg: 2.758 ± 0.488
1.609CysSer: 1.609 ± 0.684
2.298CysThr: 2.298 ± 0.676
2.068CysVal: 2.068 ± 0.78
0.46CysTrp: 0.46 ± 0.257
0.23CysTyr: 0.23 ± 0.221
0.0CysXaa: 0.0 ± 0.0
Asp
2.528AspAla: 2.528 ± 0.938
0.689AspCys: 0.689 ± 0.32
2.758AspAsp: 2.758 ± 1.113
5.976AspGlu: 5.976 ± 1.001
3.218AspPhe: 3.218 ± 0.672
4.597AspGly: 4.597 ± 0.856
0.689AspHis: 0.689 ± 0.388
2.528AspIle: 2.528 ± 0.557
3.218AspLys: 3.218 ± 0.895
3.218AspLeu: 3.218 ± 0.673
1.839AspMet: 1.839 ± 0.695
2.758AspAsn: 2.758 ± 0.574
1.839AspPro: 1.839 ± 0.502
3.447AspGln: 3.447 ± 0.97
3.677AspArg: 3.677 ± 0.711
3.447AspSer: 3.447 ± 0.761
3.907AspThr: 3.907 ± 1.19
3.447AspVal: 3.447 ± 0.689
1.149AspTrp: 1.149 ± 0.653
0.919AspTyr: 0.919 ± 0.337
0.0AspXaa: 0.0 ± 0.0
Glu
5.286GluAla: 5.286 ± 0.839
1.609GluCys: 1.609 ± 0.456
4.826GluAsp: 4.826 ± 1.267
7.355GluGlu: 7.355 ± 1.55
2.528GluPhe: 2.528 ± 0.68
5.746GluGly: 5.746 ± 1.108
0.919GluHis: 0.919 ± 0.322
3.218GluIle: 3.218 ± 0.88
6.205GluLys: 6.205 ± 1.363
6.435GluLeu: 6.435 ± 1.269
2.068GluMet: 2.068 ± 0.636
3.218GluAsn: 3.218 ± 0.466
2.068GluPro: 2.068 ± 0.558
2.298GluGln: 2.298 ± 0.574
3.907GluArg: 3.907 ± 0.989
3.447GluSer: 3.447 ± 0.928
4.367GluThr: 4.367 ± 0.936
5.516GluVal: 5.516 ± 0.92
0.689GluTrp: 0.689 ± 0.287
2.068GluTyr: 2.068 ± 0.785
0.0GluXaa: 0.0 ± 0.0
Phe
0.919PheAla: 0.919 ± 0.427
1.379PheCys: 1.379 ± 0.605
2.528PheAsp: 2.528 ± 0.789
2.528PheGlu: 2.528 ± 0.382
0.689PhePhe: 0.689 ± 0.305
1.379PheGly: 1.379 ± 0.406
0.46PheHis: 0.46 ± 0.257
3.218PheIle: 3.218 ± 0.689
0.46PheLys: 0.46 ± 0.327
3.907PheLeu: 3.907 ± 0.723
0.919PheMet: 0.919 ± 0.486
1.839PheAsn: 1.839 ± 0.647
1.609PhePro: 1.609 ± 0.48
1.379PheGln: 1.379 ± 0.395
2.068PheArg: 2.068 ± 0.414
3.907PheSer: 3.907 ± 0.781
4.137PheThr: 4.137 ± 0.949
2.758PheVal: 2.758 ± 0.868
0.23PheTrp: 0.23 ± 0.214
0.919PheTyr: 0.919 ± 0.413
0.0PheXaa: 0.0 ± 0.0
Gly
3.907GlyAla: 3.907 ± 0.711
1.609GlyCys: 1.609 ± 0.623
4.597GlyAsp: 4.597 ± 0.757
6.895GlyGlu: 6.895 ± 1.267
2.758GlyPhe: 2.758 ± 0.865
6.435GlyGly: 6.435 ± 0.819
0.689GlyHis: 0.689 ± 0.307
4.137GlyIle: 4.137 ± 0.906
6.205GlyLys: 6.205 ± 0.83
7.125GlyLeu: 7.125 ± 1.258
3.447GlyMet: 3.447 ± 0.884
3.447GlyAsn: 3.447 ± 0.876
2.528GlyPro: 2.528 ± 0.685
2.298GlyGln: 2.298 ± 0.551
4.137GlyArg: 4.137 ± 1.125
6.205GlySer: 6.205 ± 1.249
3.677GlyThr: 3.677 ± 0.767
8.504GlyVal: 8.504 ± 0.855
1.379GlyTrp: 1.379 ± 0.555
2.298GlyTyr: 2.298 ± 0.601
0.0GlyXaa: 0.0 ± 0.0
His
0.919HisAla: 0.919 ± 0.498
0.46HisCys: 0.46 ± 0.31
0.689HisAsp: 0.689 ± 0.417
0.46HisGlu: 0.46 ± 0.314
0.46HisPhe: 0.46 ± 0.242
2.068HisGly: 2.068 ± 0.703
0.689HisHis: 0.689 ± 0.284
0.46HisIle: 0.46 ± 0.38
0.919HisLys: 0.919 ± 0.489
1.149HisLeu: 1.149 ± 0.678
0.23HisMet: 0.23 ± 0.214
0.46HisAsn: 0.46 ± 0.278
0.0HisPro: 0.0 ± 0.0
0.23HisGln: 0.23 ± 0.279
0.919HisArg: 0.919 ± 0.54
1.379HisSer: 1.379 ± 0.455
0.46HisThr: 0.46 ± 0.294
0.46HisVal: 0.46 ± 0.278
0.46HisTrp: 0.46 ± 0.214
0.23HisTyr: 0.23 ± 0.206
0.0HisXaa: 0.0 ± 0.0
Ile
3.447IleAla: 3.447 ± 1.11
0.919IleCys: 0.919 ± 0.406
2.298IleAsp: 2.298 ± 0.478
2.298IleGlu: 2.298 ± 0.74
1.839IlePhe: 1.839 ± 0.542
4.137IleGly: 4.137 ± 1.09
0.23IleHis: 0.23 ± 0.206
2.988IleIle: 2.988 ± 0.721
3.218IleLys: 3.218 ± 0.957
2.068IleLeu: 2.068 ± 0.649
1.379IleMet: 1.379 ± 0.903
2.528IleAsn: 2.528 ± 0.742
1.839IlePro: 1.839 ± 0.56
2.298IleGln: 2.298 ± 0.58
2.528IleArg: 2.528 ± 0.662
5.746IleSer: 5.746 ± 0.91
2.988IleThr: 2.988 ± 0.513
3.907IleVal: 3.907 ± 0.714
1.609IleTrp: 1.609 ± 0.297
1.149IleTyr: 1.149 ± 0.781
0.0IleXaa: 0.0 ± 0.0
Lys
4.597LysAla: 4.597 ± 0.814
1.839LysCys: 1.839 ± 0.511
3.218LysAsp: 3.218 ± 0.644
3.907LysGlu: 3.907 ± 0.662
1.609LysPhe: 1.609 ± 0.555
6.435LysGly: 6.435 ± 1.121
1.379LysHis: 1.379 ± 0.477
3.218LysIle: 3.218 ± 0.816
4.137LysLys: 4.137 ± 0.935
4.826LysLeu: 4.826 ± 0.927
3.907LysMet: 3.907 ± 1.02
2.988LysAsn: 2.988 ± 0.792
2.298LysPro: 2.298 ± 0.705
1.609LysGln: 1.609 ± 0.455
4.367LysArg: 4.367 ± 1.385
4.597LysSer: 4.597 ± 1.091
5.056LysThr: 5.056 ± 1.101
5.976LysVal: 5.976 ± 1.032
0.919LysTrp: 0.919 ± 0.424
3.677LysTyr: 3.677 ± 0.87
0.0LysXaa: 0.0 ± 0.0
Leu
3.907LeuAla: 3.907 ± 0.929
2.298LeuCys: 2.298 ± 0.606
5.516LeuAsp: 5.516 ± 1.047
7.355LeuGlu: 7.355 ± 1.098
2.298LeuPhe: 2.298 ± 0.644
5.286LeuGly: 5.286 ± 1.208
1.839LeuHis: 1.839 ± 0.71
3.677LeuIle: 3.677 ± 0.527
8.504LeuLys: 8.504 ± 1.623
6.435LeuLeu: 6.435 ± 0.75
2.758LeuMet: 2.758 ± 0.744
3.218LeuAsn: 3.218 ± 0.508
1.379LeuPro: 1.379 ± 0.653
2.758LeuGln: 2.758 ± 0.488
4.826LeuArg: 4.826 ± 0.883
4.597LeuSer: 4.597 ± 1.155
4.597LeuThr: 4.597 ± 1.012
5.286LeuVal: 5.286 ± 0.743
0.919LeuTrp: 0.919 ± 0.322
2.068LeuTyr: 2.068 ± 0.616
0.0LeuXaa: 0.0 ± 0.0
Met
3.218MetAla: 3.218 ± 0.776
1.149MetCys: 1.149 ± 0.621
2.758MetAsp: 2.758 ± 0.845
3.218MetGlu: 3.218 ± 0.943
0.689MetPhe: 0.689 ± 0.437
4.367MetGly: 4.367 ± 1.006
0.23MetHis: 0.23 ± 0.279
2.298MetIle: 2.298 ± 0.667
2.528MetLys: 2.528 ± 0.73
2.068MetLeu: 2.068 ± 0.843
1.839MetMet: 1.839 ± 0.434
0.919MetAsn: 0.919 ± 0.412
0.46MetPro: 0.46 ± 0.308
0.919MetGln: 0.919 ± 0.41
3.677MetArg: 3.677 ± 0.684
3.218MetSer: 3.218 ± 0.697
2.298MetThr: 2.298 ± 0.612
3.218MetVal: 3.218 ± 1.15
0.23MetTrp: 0.23 ± 0.166
0.919MetTyr: 0.919 ± 0.387
0.0MetXaa: 0.0 ± 0.0
Asn
2.298AsnAla: 2.298 ± 0.439
0.46AsnCys: 0.46 ± 0.281
2.068AsnAsp: 2.068 ± 0.609
2.528AsnGlu: 2.528 ± 1.164
2.528AsnPhe: 2.528 ± 0.431
4.826AsnGly: 4.826 ± 1.287
0.46AsnHis: 0.46 ± 0.31
2.068AsnIle: 2.068 ± 0.648
2.988AsnLys: 2.988 ± 0.843
3.218AsnLeu: 3.218 ± 0.47
1.609AsnMet: 1.609 ± 0.58
0.689AsnAsn: 0.689 ± 0.352
1.379AsnPro: 1.379 ± 0.374
2.528AsnGln: 2.528 ± 0.616
1.609AsnArg: 1.609 ± 0.561
2.298AsnSer: 2.298 ± 0.972
2.988AsnThr: 2.988 ± 1.038
2.758AsnVal: 2.758 ± 0.742
0.689AsnTrp: 0.689 ± 0.309
0.23AsnTyr: 0.23 ± 0.273
0.0AsnXaa: 0.0 ± 0.0
Pro
1.379ProAla: 1.379 ± 0.489
1.149ProCys: 1.149 ± 0.443
2.758ProAsp: 2.758 ± 0.66
3.447ProGlu: 3.447 ± 0.752
0.919ProPhe: 0.919 ± 0.438
2.758ProGly: 2.758 ± 1.01
0.0ProHis: 0.0 ± 0.0
0.919ProIle: 0.919 ± 0.345
2.068ProLys: 2.068 ± 0.386
1.609ProLeu: 1.609 ± 0.696
0.919ProMet: 0.919 ± 0.511
0.46ProAsn: 0.46 ± 0.284
1.379ProPro: 1.379 ± 0.549
0.919ProGln: 0.919 ± 0.425
1.839ProArg: 1.839 ± 0.546
2.988ProSer: 2.988 ± 0.775
2.758ProThr: 2.758 ± 1.044
1.609ProVal: 1.609 ± 0.581
0.689ProTrp: 0.689 ± 0.442
0.46ProTyr: 0.46 ± 0.42
0.0ProXaa: 0.0 ± 0.0
Gln
1.839GlnAla: 1.839 ± 0.428
0.23GlnCys: 0.23 ± 0.214
1.149GlnAsp: 1.149 ± 0.553
1.609GlnGlu: 1.609 ± 0.566
0.689GlnPhe: 0.689 ± 0.376
3.907GlnGly: 3.907 ± 0.768
1.149GlnHis: 1.149 ± 0.522
1.379GlnIle: 1.379 ± 0.502
2.758GlnLys: 2.758 ± 0.624
2.298GlnLeu: 2.298 ± 0.518
1.149GlnMet: 1.149 ± 0.468
1.839GlnAsn: 1.839 ± 0.493
0.46GlnPro: 0.46 ± 0.366
0.919GlnGln: 0.919 ± 0.39
2.758GlnArg: 2.758 ± 0.746
2.988GlnSer: 2.988 ± 0.714
1.839GlnThr: 1.839 ± 0.596
1.839GlnVal: 1.839 ± 0.581
0.23GlnTrp: 0.23 ± 0.272
0.23GlnTyr: 0.23 ± 0.183
0.0GlnXaa: 0.0 ± 0.0
Arg
4.137ArgAla: 4.137 ± 0.985
1.149ArgCys: 1.149 ± 0.363
2.758ArgAsp: 2.758 ± 0.646
5.056ArgGlu: 5.056 ± 0.996
2.068ArgPhe: 2.068 ± 1.008
4.367ArgGly: 4.367 ± 0.94
1.149ArgHis: 1.149 ± 0.412
4.137ArgIle: 4.137 ± 0.983
4.367ArgLys: 4.367 ± 1.413
3.907ArgLeu: 3.907 ± 0.467
2.528ArgMet: 2.528 ± 0.689
2.988ArgAsn: 2.988 ± 1.078
1.149ArgPro: 1.149 ± 0.597
0.919ArgGln: 0.919 ± 0.447
4.597ArgArg: 4.597 ± 1.462
5.056ArgSer: 5.056 ± 1.375
4.826ArgThr: 4.826 ± 0.905
5.056ArgVal: 5.056 ± 0.632
0.46ArgTrp: 0.46 ± 0.278
0.919ArgTyr: 0.919 ± 0.307
0.0ArgXaa: 0.0 ± 0.0
Ser
5.286SerAla: 5.286 ± 1.319
2.758SerCys: 2.758 ± 0.969
4.367SerAsp: 4.367 ± 1.154
4.597SerGlu: 4.597 ± 0.981
4.367SerPhe: 4.367 ± 1.168
6.435SerGly: 6.435 ± 1.283
0.689SerHis: 0.689 ± 0.438
2.988SerIle: 2.988 ± 0.736
5.286SerLys: 5.286 ± 0.64
6.205SerLeu: 6.205 ± 1.121
3.907SerMet: 3.907 ± 0.939
2.068SerAsn: 2.068 ± 1.043
2.298SerPro: 2.298 ± 0.711
2.988SerGln: 2.988 ± 0.672
4.826SerArg: 4.826 ± 1.171
5.516SerSer: 5.516 ± 1.229
4.826SerThr: 4.826 ± 0.967
4.826SerVal: 4.826 ± 0.896
1.149SerTrp: 1.149 ± 0.489
0.919SerTyr: 0.919 ± 0.453
0.0SerXaa: 0.0 ± 0.0
Thr
2.758ThrAla: 2.758 ± 0.641
2.068ThrCys: 2.068 ± 0.51
4.367ThrAsp: 4.367 ± 1.492
4.597ThrGlu: 4.597 ± 1.115
2.988ThrPhe: 2.988 ± 0.96
5.516ThrGly: 5.516 ± 1.243
0.23ThrHis: 0.23 ± 0.183
3.218ThrIle: 3.218 ± 0.887
4.367ThrLys: 4.367 ± 0.524
6.435ThrLeu: 6.435 ± 1.159
2.758ThrMet: 2.758 ± 0.881
2.068ThrAsn: 2.068 ± 0.649
2.758ThrPro: 2.758 ± 1.302
1.839ThrGln: 1.839 ± 0.997
3.447ThrArg: 3.447 ± 0.654
6.435ThrSer: 6.435 ± 1.046
5.056ThrThr: 5.056 ± 0.702
3.907ThrVal: 3.907 ± 1.087
0.689ThrTrp: 0.689 ± 0.422
0.689ThrTyr: 0.689 ± 0.488
0.0ThrXaa: 0.0 ± 0.0
Val
4.367ValAla: 4.367 ± 0.833
1.609ValCys: 1.609 ± 0.682
3.218ValAsp: 3.218 ± 0.499
5.976ValGlu: 5.976 ± 0.611
2.298ValPhe: 2.298 ± 0.641
5.746ValGly: 5.746 ± 0.929
0.919ValHis: 0.919 ± 0.514
1.609ValIle: 1.609 ± 0.45
6.665ValLys: 6.665 ± 1.357
6.895ValLeu: 6.895 ± 1.153
2.758ValMet: 2.758 ± 0.877
4.137ValAsn: 4.137 ± 0.758
2.528ValPro: 2.528 ± 0.755
1.149ValGln: 1.149 ± 0.437
4.137ValArg: 4.137 ± 0.681
6.205ValSer: 6.205 ± 1.361
3.677ValThr: 3.677 ± 0.569
6.435ValVal: 6.435 ± 1.04
0.689ValTrp: 0.689 ± 0.585
2.758ValTyr: 2.758 ± 0.667
0.0ValXaa: 0.0 ± 0.0
Trp
0.46TrpAla: 0.46 ± 0.309
0.46TrpCys: 0.46 ± 0.413
0.46TrpAsp: 0.46 ± 0.332
0.23TrpGlu: 0.23 ± 0.166
0.23TrpPhe: 0.23 ± 0.206
1.379TrpGly: 1.379 ± 0.581
0.46TrpHis: 0.46 ± 0.42
0.689TrpIle: 0.689 ± 0.372
0.919TrpLys: 0.919 ± 0.478
2.528TrpLeu: 2.528 ± 0.675
1.149TrpMet: 1.149 ± 0.505
0.23TrpAsn: 0.23 ± 0.183
0.0TrpPro: 0.0 ± 0.0
1.149TrpGln: 1.149 ± 0.446
1.379TrpArg: 1.379 ± 0.529
0.919TrpSer: 0.919 ± 0.399
0.46TrpThr: 0.46 ± 0.366
0.0TrpVal: 0.0 ± 0.0
0.23TrpTrp: 0.23 ± 0.206
0.689TrpTyr: 0.689 ± 0.471
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.919TyrAla: 0.919 ± 0.578
0.46TyrCys: 0.46 ± 0.34
1.379TyrAsp: 1.379 ± 0.449
2.068TyrGlu: 2.068 ± 0.912
0.46TyrPhe: 0.46 ± 0.298
1.839TyrGly: 1.839 ± 0.567
0.46TyrHis: 0.46 ± 0.318
1.609TyrIle: 1.609 ± 0.431
1.379TyrLys: 1.379 ± 0.849
1.839TyrLeu: 1.839 ± 0.582
0.919TyrMet: 0.919 ± 0.418
1.149TyrAsn: 1.149 ± 0.373
0.919TyrPro: 0.919 ± 0.585
0.23TyrGln: 0.23 ± 0.166
1.149TyrArg: 1.149 ± 0.63
0.919TyrSer: 0.919 ± 0.369
1.609TyrThr: 1.609 ± 0.469
2.528TyrVal: 2.528 ± 0.655
0.46TyrTrp: 0.46 ± 0.258
0.689TyrTyr: 0.689 ± 0.285
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 10 proteins (4352 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski