Amino acid dipepetide frequency for Pogonomyrmex barbatus (red harvester ant)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.445AlaAla: 5.445 ± 0.05	1.167AlaCys: 1.167 ± 0.013	3.019AlaAsp: 3.019 ± 0.018	3.967AlaGlu: 3.967 ± 0.031	2.124AlaPhe: 2.124 ± 0.02	3.491AlaGly: 3.491 ± 0.03	1.418AlaHis: 1.418 ± 0.013	3.634AlaIle: 3.634 ± 0.023	3.564AlaLys: 3.564 ± 0.024	5.742AlaLeu: 5.742 ± 0.037	1.568AlaMet: 1.568 ± 0.014	2.82AlaAsn: 2.82 ± 0.021	2.797AlaPro: 2.797 ± 0.027	2.491AlaGln: 2.491 ± 0.023	3.476AlaArg: 3.476 ± 0.026	5.001AlaSer: 5.001 ± 0.034	4.139AlaThr: 4.139 ± 0.029	3.917AlaVal: 3.917 ± 0.025	0.63AlaTrp: 0.63 ± 0.011	1.621AlaTyr: 1.621 ± 0.014	0.002AlaXaa: 0.002 ± 0.001
Cys	1.118CysAla: 1.118 ± 0.016	0.452CysCys: 0.452 ± 0.009	1.162CysAsp: 1.162 ± 0.022	1.156CysGlu: 1.156 ± 0.017	0.693CysPhe: 0.693 ± 0.01	1.233CysGly: 1.233 ± 0.018	0.526CysHis: 0.526 ± 0.009	1.17CysIle: 1.17 ± 0.018	1.136CysLys: 1.136 ± 0.012	1.779CysLeu: 1.779 ± 0.018	0.397CysMet: 0.397 ± 0.007	1.011CysAsn: 1.011 ± 0.014	1.007CysPro: 1.007 ± 0.019	0.773CysGln: 0.773 ± 0.013	1.081CysArg: 1.081 ± 0.018	1.506CysSer: 1.506 ± 0.017	1.102CysThr: 1.102 ± 0.015	1.148CysVal: 1.148 ± 0.015	0.224CysTrp: 0.224 ± 0.005	0.585CysTyr: 0.585 ± 0.01	0.002CysXaa: 0.002 ± 0.0
Asp	3.139AspAla: 3.139 ± 0.022	1.033AspCys: 1.033 ± 0.018	3.831AspAsp: 3.831 ± 0.039	4.291AspGlu: 4.291 ± 0.033	2.084AspPhe: 2.084 ± 0.019	3.181AspGly: 3.181 ± 0.037	1.155AspHis: 1.155 ± 0.013	3.679AspIle: 3.679 ± 0.024	3.351AspLys: 3.351 ± 0.027	4.814AspLeu: 4.814 ± 0.033	1.311AspMet: 1.311 ± 0.013	2.861AspAsn: 2.861 ± 0.025	2.437AspPro: 2.437 ± 0.022	1.753AspGln: 1.753 ± 0.016	2.892AspArg: 2.892 ± 0.03	4.449AspSer: 4.449 ± 0.032	3.126AspThr: 3.126 ± 0.021	3.551AspVal: 3.551 ± 0.024	0.62AspTrp: 0.62 ± 0.008	1.846AspTyr: 1.846 ± 0.015	0.004AspXaa: 0.004 ± 0.001
Glu	4.006GluAla: 4.006 ± 0.032	1.213GluCys: 1.213 ± 0.018	4.273GluAsp: 4.273 ± 0.033	6.386GluGlu: 6.386 ± 0.069	2.091GluPhe: 2.091 ± 0.018	2.909GluGly: 2.909 ± 0.025	1.54GluHis: 1.54 ± 0.013	4.132GluIle: 4.132 ± 0.033	5.175GluLys: 5.175 ± 0.051	5.784GluLeu: 5.784 ± 0.043	1.674GluMet: 1.674 ± 0.014	3.923GluAsn: 3.923 ± 0.03	2.456GluPro: 2.456 ± 0.024	2.914GluGln: 2.914 ± 0.03	4.109GluArg: 4.109 ± 0.034	4.747GluSer: 4.747 ± 0.035	3.878GluThr: 3.878 ± 0.031	3.591GluVal: 3.591 ± 0.026	0.662GluTrp: 0.662 ± 0.008	1.973GluTyr: 1.973 ± 0.016	0.005GluXaa: 0.005 ± 0.001
Phe	2.112PheAla: 2.112 ± 0.017	0.762PheCys: 0.762 ± 0.011	1.992PheAsp: 1.992 ± 0.019	2.045PheGlu: 2.045 ± 0.02	1.395PhePhe: 1.395 ± 0.017	2.09PheGly: 2.09 ± 0.022	0.934PheHis: 0.934 ± 0.01	2.049PheIle: 2.049 ± 0.021	1.954PheLys: 1.954 ± 0.018	3.44PheLeu: 3.44 ± 0.027	0.785PheMet: 0.785 ± 0.012	1.681PheAsn: 1.681 ± 0.016	1.581PhePro: 1.581 ± 0.015	1.378PheGln: 1.378 ± 0.014	1.773PheArg: 1.773 ± 0.02	2.682PheSer: 2.682 ± 0.022	2.022PheThr: 2.022 ± 0.017	2.296PheVal: 2.296 ± 0.022	0.416PheTrp: 0.416 ± 0.008	1.246PheTyr: 1.246 ± 0.014	0.007PheXaa: 0.007 ± 0.001
Gly	3.148GlyAla: 3.148 ± 0.027	0.972GlyCys: 0.972 ± 0.014	2.939GlyAsp: 2.939 ± 0.029	3.175GlyGlu: 3.175 ± 0.027	2.029GlyPhe: 2.029 ± 0.02	4.482GlyGly: 4.482 ± 0.054	1.401GlyHis: 1.401 ± 0.019	3.278GlyIle: 3.278 ± 0.025	3.26GlyLys: 3.26 ± 0.025	4.404GlyLeu: 4.404 ± 0.031	1.255GlyMet: 1.255 ± 0.016	2.783GlyAsn: 2.783 ± 0.023	2.487GlyPro: 2.487 ± 0.038	2.051GlyGln: 2.051 ± 0.019	3.065GlyArg: 3.065 ± 0.024	4.791GlySer: 4.791 ± 0.039	3.325GlyThr: 3.325 ± 0.029	3.142GlyVal: 3.142 ± 0.03	0.618GlyTrp: 0.618 ± 0.011	1.96GlyTyr: 1.96 ± 0.026	0.005GlyXaa: 0.005 ± 0.001
His	1.442HisAla: 1.442 ± 0.014	0.6HisCys: 0.6 ± 0.012	1.149HisAsp: 1.149 ± 0.014	1.429HisGlu: 1.429 ± 0.015	0.936HisPhe: 0.936 ± 0.011	1.413HisGly: 1.413 ± 0.019	1.184HisHis: 1.184 ± 0.028	1.469HisIle: 1.469 ± 0.015	1.34HisLys: 1.34 ± 0.014	2.289HisLeu: 2.289 ± 0.019	0.636HisMet: 0.636 ± 0.009	1.187HisAsn: 1.187 ± 0.013	1.423HisPro: 1.423 ± 0.017	1.177HisGln: 1.177 ± 0.017	1.567HisArg: 1.567 ± 0.016	1.994HisSer: 1.994 ± 0.019	1.409HisThr: 1.409 ± 0.013	1.523HisVal: 1.523 ± 0.014	0.29HisTrp: 0.29 ± 0.006	0.871HisTyr: 0.871 ± 0.011	0.002HisXaa: 0.002 ± 0.0
Ile	3.79IleAla: 3.79 ± 0.026	1.289IleCys: 1.289 ± 0.015	3.368IleAsp: 3.368 ± 0.025	3.837IleGlu: 3.837 ± 0.032	2.301IlePhe: 2.301 ± 0.024	3.031IleGly: 3.031 ± 0.025	1.392IleHis: 1.392 ± 0.015	3.631IleIle: 3.631 ± 0.034	3.629IleLys: 3.629 ± 0.029	5.61IleLeu: 5.61 ± 0.037	1.351IleMet: 1.351 ± 0.014	3.028IleAsn: 3.028 ± 0.024	3.001IlePro: 3.001 ± 0.024	2.417IleGln: 2.417 ± 0.02	2.922IleArg: 2.922 ± 0.023	4.719IleSer: 4.719 ± 0.03	3.481IleThr: 3.481 ± 0.03	3.735IleVal: 3.735 ± 0.024	0.597IleTrp: 0.597 ± 0.011	1.841IleTyr: 1.841 ± 0.017	0.007IleXaa: 0.007 ± 0.001
Lys	3.277LysAla: 3.277 ± 0.027	1.172LysCys: 1.172 ± 0.018	3.612LysAsp: 3.612 ± 0.031	4.879LysGlu: 4.879 ± 0.042	2.007LysPhe: 2.007 ± 0.018	2.553LysGly: 2.553 ± 0.027	1.554LysHis: 1.554 ± 0.016	3.964LysIle: 3.964 ± 0.034	5.087LysLys: 5.087 ± 0.048	5.664LysLeu: 5.664 ± 0.037	1.544LysMet: 1.544 ± 0.014	3.309LysAsn: 3.309 ± 0.029	2.735LysPro: 2.735 ± 0.028	2.746LysGln: 2.746 ± 0.023	3.881LysArg: 3.881 ± 0.028	4.689LysSer: 4.689 ± 0.039	3.497LysThr: 3.497 ± 0.027	3.317LysVal: 3.317 ± 0.024	0.637LysTrp: 0.637 ± 0.009	2.092LysTyr: 2.092 ± 0.02	0.024LysXaa: 0.024 ± 0.002
Leu	5.915LeuAla: 5.915 ± 0.039	1.752LeuCys: 1.752 ± 0.02	4.822LeuAsp: 4.822 ± 0.03	6.156LeuGlu: 6.156 ± 0.048	3.038LeuPhe: 3.038 ± 0.028	4.367LeuGly: 4.367 ± 0.023	2.461LeuHis: 2.461 ± 0.02	4.758LeuIle: 4.758 ± 0.032	5.795LeuLys: 5.795 ± 0.034	8.73LeuLeu: 8.73 ± 0.057	2.04LeuMet: 2.04 ± 0.018	4.26LeuAsn: 4.26 ± 0.029	4.694LeuPro: 4.694 ± 0.027	4.545LeuGln: 4.545 ± 0.03	5.383LeuArg: 5.383 ± 0.035	7.164LeuSer: 7.164 ± 0.034	5.107LeuThr: 5.107 ± 0.029	4.867LeuVal: 4.867 ± 0.034	0.926LeuTrp: 0.926 ± 0.012	2.763LeuTyr: 2.763 ± 0.02	0.008LeuXaa: 0.008 ± 0.001
Met	1.631MetAla: 1.631 ± 0.017	0.429MetCys: 0.429 ± 0.008	1.37MetAsp: 1.37 ± 0.012	1.732MetGlu: 1.732 ± 0.016	0.83MetPhe: 0.83 ± 0.009	1.167MetGly: 1.167 ± 0.016	0.554MetHis: 0.554 ± 0.009	1.313MetIle: 1.313 ± 0.015	1.546MetLys: 1.546 ± 0.015	2.106MetLeu: 2.106 ± 0.017	0.702MetMet: 0.702 ± 0.012	1.153MetAsn: 1.153 ± 0.014	1.178MetPro: 1.178 ± 0.013	1.135MetGln: 1.135 ± 0.014	1.298MetArg: 1.298 ± 0.013	1.906MetSer: 1.906 ± 0.017	1.389MetThr: 1.389 ± 0.011	1.216MetVal: 1.216 ± 0.013	0.252MetTrp: 0.252 ± 0.005	0.738MetTyr: 0.738 ± 0.009	0.002MetXaa: 0.002 ± 0.001
Asn	3.09AsnAla: 3.09 ± 0.023	0.905AsnCys: 0.905 ± 0.015	2.866AsnAsp: 2.866 ± 0.025	3.339AsnGlu: 3.339 ± 0.028	1.758AsnPhe: 1.758 ± 0.018	3.004AsnGly: 3.004 ± 0.027	1.182AsnHis: 1.182 ± 0.013	3.551AsnIle: 3.551 ± 0.027	3.201AsnLys: 3.201 ± 0.025	4.515AsnLeu: 4.515 ± 0.03	1.229AsnMet: 1.229 ± 0.014	3.355AsnAsn: 3.355 ± 0.036	2.267AsnPro: 2.267 ± 0.023	2.034AsnGln: 2.034 ± 0.02	2.439AsnArg: 2.439 ± 0.02	4.056AsnSer: 4.056 ± 0.029	2.911AsnThr: 2.911 ± 0.023	3.442AsnVal: 3.442 ± 0.022	0.516AsnTrp: 0.516 ± 0.008	1.641AsnTyr: 1.641 ± 0.016	0.006AsnXaa: 0.006 ± 0.001
Pro	3.144ProAla: 3.144 ± 0.026	0.776ProCys: 0.776 ± 0.016	2.564ProAsp: 2.564 ± 0.02	3.25ProGlu: 3.25 ± 0.026	1.547ProPhe: 1.547 ± 0.017	3.029ProGly: 3.029 ± 0.055	1.298ProHis: 1.298 ± 0.015	2.725ProIle: 2.725 ± 0.023	2.562ProLys: 2.562 ± 0.022	4.097ProLeu: 4.097 ± 0.026	1.094ProMet: 1.094 ± 0.014	2.294ProAsn: 2.294 ± 0.02	4.548ProPro: 4.548 ± 0.071	2.181ProGln: 2.181 ± 0.023	2.697ProArg: 2.697 ± 0.021	4.518ProSer: 4.518 ± 0.041	3.296ProThr: 3.296 ± 0.028	3.126ProVal: 3.126 ± 0.028	0.492ProTrp: 0.492 ± 0.009	1.546ProTyr: 1.546 ± 0.016	0.005ProXaa: 0.005 ± 0.001
Gln	2.57GlnAla: 2.57 ± 0.023	0.832GlnCys: 0.832 ± 0.015	2.075GlnAsp: 2.075 ± 0.017	3.053GlnGlu: 3.053 ± 0.027	1.333GlnPhe: 1.333 ± 0.016	1.927GlnGly: 1.927 ± 0.018	1.315GlnHis: 1.315 ± 0.018	2.417GlnIle: 2.417 ± 0.019	2.597GlnLys: 2.597 ± 0.024	3.974GlnLeu: 3.974 ± 0.028	1.054GlnMet: 1.054 ± 0.013	2.293GlnAsn: 2.293 ± 0.025	2.191GlnPro: 2.191 ± 0.026	4.247GlnGln: 4.247 ± 0.091	2.718GlnArg: 2.718 ± 0.024	3.265GlnSer: 3.265 ± 0.032	2.385GlnThr: 2.385 ± 0.023	2.279GlnVal: 2.279 ± 0.022	0.456GlnTrp: 0.456 ± 0.009	1.361GlnTyr: 1.361 ± 0.016	0.004GlnXaa: 0.004 ± 0.001
Arg	3.163ArgAla: 3.163 ± 0.024	1.111ArgCys: 1.111 ± 0.019	3.208ArgAsp: 3.208 ± 0.03	3.843ArgGlu: 3.843 ± 0.029	1.895ArgPhe: 1.895 ± 0.016	3.03ArgGly: 3.03 ± 0.033	1.59ArgHis: 1.59 ± 0.016	3.135ArgIle: 3.135 ± 0.022	3.933ArgLys: 3.933 ± 0.03	5.037ArgLeu: 5.037 ± 0.034	1.248ArgMet: 1.248 ± 0.012	2.974ArgAsn: 2.974 ± 0.02	2.63ArgPro: 2.63 ± 0.025	2.47ArgGln: 2.47 ± 0.02	4.472ArgArg: 4.472 ± 0.04	4.684ArgSer: 4.684 ± 0.041	2.948ArgThr: 2.948 ± 0.022	2.974ArgVal: 2.974 ± 0.021	0.632ArgTrp: 0.632 ± 0.008	1.879ArgTyr: 1.879 ± 0.02	0.006ArgXaa: 0.006 ± 0.001
Ser	4.743SerAla: 4.743 ± 0.032	1.411SerCys: 1.411 ± 0.015	4.481SerAsp: 4.481 ± 0.031	4.84SerGlu: 4.84 ± 0.037	2.651SerPhe: 2.651 ± 0.021	4.878SerGly: 4.878 ± 0.039	1.905SerHis: 1.905 ± 0.019	4.41SerIle: 4.41 ± 0.029	4.576SerLys: 4.576 ± 0.034	7.068SerLeu: 7.068 ± 0.035	1.855SerMet: 1.855 ± 0.017	4.274SerAsn: 4.274 ± 0.03	4.808SerPro: 4.808 ± 0.048	3.431SerGln: 3.431 ± 0.026	4.646SerArg: 4.646 ± 0.044	8.944SerSer: 8.944 ± 0.076	5.446SerThr: 5.446 ± 0.042	4.778SerVal: 4.778 ± 0.028	0.839SerTrp: 0.839 ± 0.011	2.269SerTyr: 2.269 ± 0.021	0.003SerXaa: 0.003 ± 0.001
Thr	3.973ThrAla: 3.973 ± 0.03	1.196ThrCys: 1.196 ± 0.019	3.108ThrAsp: 3.108 ± 0.022	3.723ThrGlu: 3.723 ± 0.032	2.095ThrPhe: 2.095 ± 0.018	3.377ThrGly: 3.377 ± 0.029	1.287ThrHis: 1.287 ± 0.014	3.551ThrIle: 3.551 ± 0.027	3.373ThrLys: 3.373 ± 0.027	5.34ThrLeu: 5.34 ± 0.032	1.447ThrMet: 1.447 ± 0.014	2.969ThrAsn: 2.969 ± 0.022	3.455ThrPro: 3.455 ± 0.034	2.279ThrGln: 2.279 ± 0.021	2.915ThrArg: 2.915 ± 0.022	5.415ThrSer: 5.415 ± 0.041	4.578ThrThr: 4.578 ± 0.056	3.89ThrVal: 3.89 ± 0.03	0.64ThrTrp: 0.64 ± 0.01	1.728ThrTyr: 1.728 ± 0.016	0.004ThrXaa: 0.004 ± 0.001
Val	3.999ValAla: 3.999 ± 0.027	1.252ValCys: 1.252 ± 0.015	3.224ValAsp: 3.224 ± 0.021	3.798ValGlu: 3.798 ± 0.029	2.095ValPhe: 2.095 ± 0.019	3.018ValGly: 3.018 ± 0.025	1.465ValHis: 1.465 ± 0.016	3.576ValIle: 3.576 ± 0.024	3.52ValLys: 3.52 ± 0.025	5.265ValLeu: 5.265 ± 0.032	1.394ValMet: 1.394 ± 0.015	2.867ValAsn: 2.867 ± 0.023	3.195ValPro: 3.195 ± 0.031	2.565ValGln: 2.565 ± 0.021	3.054ValArg: 3.054 ± 0.025	4.601ValSer: 4.601 ± 0.026	3.919ValThr: 3.919 ± 0.029	3.71ValVal: 3.71 ± 0.027	0.635ValTrp: 0.635 ± 0.01	1.765ValTyr: 1.765 ± 0.02	0.004ValXaa: 0.004 ± 0.001
Trp	0.573TrpAla: 0.573 ± 0.009	0.224TrpCys: 0.224 ± 0.006	0.589TrpAsp: 0.589 ± 0.01	0.621TrpGlu: 0.621 ± 0.009	0.417TrpPhe: 0.417 ± 0.008	0.515TrpGly: 0.515 ± 0.009	0.286TrpHis: 0.286 ± 0.007	0.67TrpIle: 0.67 ± 0.01	0.727TrpLys: 0.727 ± 0.012	1.064TrpLeu: 1.064 ± 0.013	0.279TrpMet: 0.279 ± 0.006	0.589TrpAsn: 0.589 ± 0.01	0.41TrpPro: 0.41 ± 0.008	0.478TrpGln: 0.478 ± 0.008	0.69TrpArg: 0.69 ± 0.01	0.829TrpSer: 0.829 ± 0.01	0.614TrpThr: 0.614 ± 0.009	0.514TrpVal: 0.514 ± 0.009	0.191TrpTrp: 0.191 ± 0.006	0.357TrpTyr: 0.357 ± 0.008	0.001TrpXaa: 0.001 ± 0.0
Tyr	1.754TyrAla: 1.754 ± 0.015	0.71TyrCys: 0.71 ± 0.01	1.753TyrAsp: 1.753 ± 0.015	1.918TyrGlu: 1.918 ± 0.016	1.313TyrPhe: 1.313 ± 0.014	1.872TyrGly: 1.872 ± 0.022	0.88TyrHis: 0.88 ± 0.012	1.86TyrIle: 1.86 ± 0.021	1.888TyrLys: 1.888 ± 0.019	2.823TyrLeu: 2.823 ± 0.02	0.781TyrMet: 0.781 ± 0.011	1.667TyrAsn: 1.667 ± 0.015	1.487TyrPro: 1.487 ± 0.021	1.275TyrGln: 1.275 ± 0.014	1.777TyrArg: 1.777 ± 0.016	2.291TyrSer: 2.291 ± 0.018	1.765TyrThr: 1.765 ± 0.018	1.903TyrVal: 1.903 ± 0.017	0.365TyrTrp: 0.365 ± 0.008	1.229TyrTyr: 1.229 ± 0.016	0.003TyrXaa: 0.003 ± 0.001
Xaa	0.003XaaAla: 0.003 ± 0.001	0.001XaaCys: 0.001 ± 0.0	0.004XaaAsp: 0.004 ± 0.001	0.006XaaGlu: 0.006 ± 0.001	0.009XaaPhe: 0.009 ± 0.001	0.004XaaGly: 0.004 ± 0.001	0.001XaaHis: 0.001 ± 0.0	0.005XaaIle: 0.005 ± 0.001	0.028XaaLys: 0.028 ± 0.002	0.007XaaLeu: 0.007 ± 0.001	0.002XaaMet: 0.002 ± 0.0	0.007XaaAsn: 0.007 ± 0.001	0.002XaaPro: 0.002 ± 0.001	0.003XaaGln: 0.003 ± 0.001	0.003XaaArg: 0.003 ± 0.001	0.004XaaSer: 0.004 ± 0.001	0.005XaaThr: 0.005 ± 0.001	0.003XaaVal: 0.003 ± 0.001	0.001XaaTrp: 0.001 ± 0.0	0.003XaaTyr: 0.003 ± 0.001	0.029XaaXaa: 0.029 ± 0.004

Statistics based on 13753 proteins (8082949 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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