Treponema pedis str. T A4

Taxonomy: cellular organisms; Bacteria; Spirochaetes; Spirochaetia; Spirochaetales; Treponemataceae; Treponema; Treponema pedis

Average proteome isoelectric point is 7.03

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 2775 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|S5ZZU6|S5ZZU6_9SPIO Methyl-accepting chemotaxis protein OS=Treponema pedis str. T A4 OX=1291379 GN=TPE_1383 PE=4 SV=1
MM1 pKa = 7.86EE2 pKa = 5.05ILNYY6 pKa = 10.02EE7 pKa = 4.4LNNKK11 pKa = 8.91EE12 pKa = 4.35IIMLSEE18 pKa = 3.8KK19 pKa = 10.32VKK21 pKa = 10.95NYY23 pKa = 10.6LIEE26 pKa = 4.38TGLYY30 pKa = 10.73DD31 pKa = 3.53EE32 pKa = 5.57TEE34 pKa = 3.89DD35 pKa = 3.5TNYY38 pKa = 10.23QKK40 pKa = 11.35VMLDD44 pKa = 3.58LGIKK48 pKa = 9.98LDD50 pKa = 3.59AAFAQFNLYY59 pKa = 9.04TNAVTFSGQAYY70 pKa = 10.16DD71 pKa = 3.74IYY73 pKa = 10.47NVCWFAINSTYY84 pKa = 10.74SEE86 pKa = 4.41QIEE89 pKa = 4.35NMQSALNLPEE99 pKa = 4.6EE100 pKa = 4.63YY101 pKa = 10.13IPLDD105 pKa = 3.37SFEE108 pKa = 5.47AEE110 pKa = 4.08GGFFYY115 pKa = 10.78NLKK118 pKa = 9.05TGEE121 pKa = 4.15VLEE124 pKa = 4.91LEE126 pKa = 4.87LGQKK130 pKa = 10.66LIDD133 pKa = 3.94FQNGQLQPQWKK144 pKa = 9.5DD145 pKa = 3.43FNSFLEE151 pKa = 4.16WFFEE155 pKa = 4.66LEE157 pKa = 3.98

Molecular weight: 18.4 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|S5ZVK2|S5ZVK2_9SPIO Antitoxin OS=Treponema pedis str. T A4 OX=1291379 GN=TPE_1851 PE=3 SV=1
MM1 pKa = 7.17RR2 pKa = 11.84QSRR5 pKa = 11.84TSKK8 pKa = 10.19QILFAVCLSKK18 pKa = 11.06CGFWSGSVNACIKK31 pKa = 9.57TSPEE35 pKa = 3.26KK36 pKa = 10.19TRR38 pKa = 11.84AAKK41 pKa = 10.1RR42 pKa = 11.84LQAISVQQADD52 pKa = 3.66RR53 pKa = 11.84RR54 pKa = 11.84SIEE57 pKa = 3.75ASAVSILVYY66 pKa = 9.22FYY68 pKa = 10.58ILCNNKK74 pKa = 9.8SYY76 pKa = 11.53KK77 pKa = 9.68NASGLLRR84 pKa = 11.84SDD86 pKa = 4.06RR87 pKa = 11.84RR88 pKa = 11.84NCTGNRR94 pKa = 3.45

Molecular weight: 10.52 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

2775

0

2775

849640

37

2086

306.2

34.45

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.104 ± 0.043

1.221 ± 0.02

4.775 ± 0.035

7.155 ± 0.058

5.557 ± 0.052

6.434 ± 0.05

1.409 ± 0.018

8.589 ± 0.049

8.59 ± 0.046

9.412 ± 0.043

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.295 ± 0.021

5.329 ± 0.04

3.341 ± 0.028

2.631 ± 0.026

3.631 ± 0.027

6.707 ± 0.038

5.26 ± 0.032

5.807 ± 0.037

0.845 ± 0.015

3.907 ± 0.035
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski