Amino acid dipepetide frequency for Wilkie narna-like virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.937AlaAla: 0.937 ± 0.0
0.0AlaCys: 0.0 ± 0.0
3.749AlaAsp: 3.749 ± 0.0
1.874AlaGlu: 1.874 ± 0.0
1.874AlaPhe: 1.874 ± 0.0
2.812AlaGly: 2.812 ± 0.0
1.874AlaHis: 1.874 ± 0.0
2.812AlaIle: 2.812 ± 0.0
2.812AlaLys: 2.812 ± 0.0
7.498AlaLeu: 7.498 ± 0.0
1.874AlaMet: 1.874 ± 0.0
3.749AlaAsn: 3.749 ± 0.0
0.937AlaPro: 0.937 ± 0.0
1.874AlaGln: 1.874 ± 0.0
3.749AlaArg: 3.749 ± 0.0
3.749AlaSer: 3.749 ± 0.0
0.937AlaThr: 0.937 ± 0.0
3.749AlaVal: 3.749 ± 0.0
0.0AlaTrp: 0.0 ± 0.0
0.937AlaTyr: 0.937 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.874CysAla: 1.874 ± 0.0
0.937CysCys: 0.937 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.937CysGlu: 0.937 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.937CysGly: 0.937 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.937CysIle: 0.937 ± 0.0
0.0CysLys: 0.0 ± 0.0
4.686CysLeu: 4.686 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.937CysPro: 0.937 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.937CysArg: 0.937 ± 0.0
0.937CysSer: 0.937 ± 0.0
2.812CysThr: 2.812 ± 0.0
1.874CysVal: 1.874 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
0.937AspAla: 0.937 ± 0.0
0.937AspCys: 0.937 ± 0.0
7.498AspAsp: 7.498 ± 0.0
3.749AspGlu: 3.749 ± 0.0
2.812AspPhe: 2.812 ± 0.0
1.874AspGly: 1.874 ± 0.0
1.874AspHis: 1.874 ± 0.0
0.0AspIle: 0.0 ± 0.0
0.937AspLys: 0.937 ± 0.0
11.246AspLeu: 11.246 ± 0.0
0.937AspMet: 0.937 ± 0.0
0.937AspAsn: 0.937 ± 0.0
5.623AspPro: 5.623 ± 0.0
0.937AspGln: 0.937 ± 0.0
5.623AspArg: 5.623 ± 0.0
1.874AspSer: 1.874 ± 0.0
5.623AspThr: 5.623 ± 0.0
1.874AspVal: 1.874 ± 0.0
0.0AspTrp: 0.0 ± 0.0
5.623AspTyr: 5.623 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
3.749GluAla: 3.749 ± 0.0
0.0GluCys: 0.0 ± 0.0
2.812GluAsp: 2.812 ± 0.0
4.686GluGlu: 4.686 ± 0.0
0.0GluPhe: 0.0 ± 0.0
2.812GluGly: 2.812 ± 0.0
1.874GluHis: 1.874 ± 0.0
1.874GluIle: 1.874 ± 0.0
0.937GluLys: 0.937 ± 0.0
2.812GluLeu: 2.812 ± 0.0
0.0GluMet: 0.0 ± 0.0
0.937GluAsn: 0.937 ± 0.0
4.686GluPro: 4.686 ± 0.0
1.874GluGln: 1.874 ± 0.0
3.749GluArg: 3.749 ± 0.0
2.812GluSer: 2.812 ± 0.0
6.56GluThr: 6.56 ± 0.0
4.686GluVal: 4.686 ± 0.0
0.0GluTrp: 0.0 ± 0.0
3.749GluTyr: 3.749 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.937PheCys: 0.937 ± 0.0
0.937PheAsp: 0.937 ± 0.0
1.874PheGlu: 1.874 ± 0.0
1.874PhePhe: 1.874 ± 0.0
0.937PheGly: 0.937 ± 0.0
1.874PheHis: 1.874 ± 0.0
2.812PheIle: 2.812 ± 0.0
3.749PheLys: 3.749 ± 0.0
6.56PheLeu: 6.56 ± 0.0
2.812PheMet: 2.812 ± 0.0
2.812PheAsn: 2.812 ± 0.0
1.874PhePro: 1.874 ± 0.0
0.0PheGln: 0.0 ± 0.0
6.56PheArg: 6.56 ± 0.0
2.812PheSer: 2.812 ± 0.0
2.812PheThr: 2.812 ± 0.0
0.937PheVal: 0.937 ± 0.0
0.937PheTrp: 0.937 ± 0.0
2.812PheTyr: 2.812 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
0.0GlyAla: 0.0 ± 0.0
0.937GlyCys: 0.937 ± 0.0
3.749GlyAsp: 3.749 ± 0.0
0.937GlyGlu: 0.937 ± 0.0
1.874GlyPhe: 1.874 ± 0.0
2.812GlyGly: 2.812 ± 0.0
0.0GlyHis: 0.0 ± 0.0
0.937GlyIle: 0.937 ± 0.0
1.874GlyLys: 1.874 ± 0.0
3.749GlyLeu: 3.749 ± 0.0
1.874GlyMet: 1.874 ± 0.0
1.874GlyAsn: 1.874 ± 0.0
5.623GlyPro: 5.623 ± 0.0
2.812GlyGln: 2.812 ± 0.0
7.498GlyArg: 7.498 ± 0.0
5.623GlySer: 5.623 ± 0.0
2.812GlyThr: 2.812 ± 0.0
2.812GlyVal: 2.812 ± 0.0
3.749GlyTrp: 3.749 ± 0.0
5.623GlyTyr: 5.623 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.937HisAla: 0.937 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.874HisGlu: 1.874 ± 0.0
0.937HisPhe: 0.937 ± 0.0
2.812HisGly: 2.812 ± 0.0
1.874HisHis: 1.874 ± 0.0
2.812HisIle: 2.812 ± 0.0
0.0HisLys: 0.0 ± 0.0
2.812HisLeu: 2.812 ± 0.0
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
2.812HisPro: 2.812 ± 0.0
0.937HisGln: 0.937 ± 0.0
2.812HisArg: 2.812 ± 0.0
0.0HisSer: 0.0 ± 0.0
0.937HisThr: 0.937 ± 0.0
0.937HisVal: 0.937 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
0.0IleCys: 0.0 ± 0.0
3.749IleAsp: 3.749 ± 0.0
2.812IleGlu: 2.812 ± 0.0
2.812IlePhe: 2.812 ± 0.0
2.812IleGly: 2.812 ± 0.0
1.874IleHis: 1.874 ± 0.0
0.0IleIle: 0.0 ± 0.0
1.874IleLys: 1.874 ± 0.0
5.623IleLeu: 5.623 ± 0.0
0.0IleMet: 0.0 ± 0.0
0.0IleAsn: 0.0 ± 0.0
3.749IlePro: 3.749 ± 0.0
2.812IleGln: 2.812 ± 0.0
3.749IleArg: 3.749 ± 0.0
6.56IleSer: 6.56 ± 0.0
2.812IleThr: 2.812 ± 0.0
1.874IleVal: 1.874 ± 0.0
1.874IleTrp: 1.874 ± 0.0
0.937IleTyr: 0.937 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
1.874LysAla: 1.874 ± 0.0
0.937LysCys: 0.937 ± 0.0
2.812LysAsp: 2.812 ± 0.0
0.937LysGlu: 0.937 ± 0.0
0.937LysPhe: 0.937 ± 0.0
0.937LysGly: 0.937 ± 0.0
0.937LysHis: 0.937 ± 0.0
2.812LysIle: 2.812 ± 0.0
1.874LysLys: 1.874 ± 0.0
5.623LysLeu: 5.623 ± 0.0
0.0LysMet: 0.0 ± 0.0
0.937LysAsn: 0.937 ± 0.0
0.937LysPro: 0.937 ± 0.0
0.937LysGln: 0.937 ± 0.0
0.0LysArg: 0.0 ± 0.0
1.874LysSer: 1.874 ± 0.0
3.749LysThr: 3.749 ± 0.0
3.749LysVal: 3.749 ± 0.0
0.937LysTrp: 0.937 ± 0.0
0.937LysTyr: 0.937 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
6.56LeuAla: 6.56 ± 0.0
0.937LeuCys: 0.937 ± 0.0
5.623LeuAsp: 5.623 ± 0.0
7.498LeuGlu: 7.498 ± 0.0
8.435LeuPhe: 8.435 ± 0.0
8.435LeuGly: 8.435 ± 0.0
1.874LeuHis: 1.874 ± 0.0
5.623LeuIle: 5.623 ± 0.0
0.937LeuLys: 0.937 ± 0.0
13.121LeuLeu: 13.121 ± 0.0
1.874LeuMet: 1.874 ± 0.0
2.812LeuAsn: 2.812 ± 0.0
6.56LeuPro: 6.56 ± 0.0
0.0LeuGln: 0.0 ± 0.0
12.184LeuArg: 12.184 ± 0.0
9.372LeuSer: 9.372 ± 0.0
5.623LeuThr: 5.623 ± 0.0
6.56LeuVal: 6.56 ± 0.0
1.874LeuTrp: 1.874 ± 0.0
2.812LeuTyr: 2.812 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
1.874MetAla: 1.874 ± 0.0
0.937MetCys: 0.937 ± 0.0
1.874MetAsp: 1.874 ± 0.0
0.937MetGlu: 0.937 ± 0.0
0.937MetPhe: 0.937 ± 0.0
1.874MetGly: 1.874 ± 0.0
0.937MetHis: 0.937 ± 0.0
2.812MetIle: 2.812 ± 0.0
0.937MetLys: 0.937 ± 0.0
0.937MetLeu: 0.937 ± 0.0
1.874MetMet: 1.874 ± 0.0
0.0MetAsn: 0.0 ± 0.0
2.812MetPro: 2.812 ± 0.0
2.812MetGln: 2.812 ± 0.0
2.812MetArg: 2.812 ± 0.0
0.937MetSer: 0.937 ± 0.0
1.874MetThr: 1.874 ± 0.0
0.937MetVal: 0.937 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.812AsnAla: 2.812 ± 0.0
1.874AsnCys: 1.874 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
3.749AsnGlu: 3.749 ± 0.0
0.937AsnPhe: 0.937 ± 0.0
3.749AsnGly: 3.749 ± 0.0
0.0AsnHis: 0.0 ± 0.0
0.0AsnIle: 0.0 ± 0.0
0.937AsnLys: 0.937 ± 0.0
4.686AsnLeu: 4.686 ± 0.0
0.937AsnMet: 0.937 ± 0.0
2.812AsnAsn: 2.812 ± 0.0
1.874AsnPro: 1.874 ± 0.0
0.937AsnGln: 0.937 ± 0.0
1.874AsnArg: 1.874 ± 0.0
2.812AsnSer: 2.812 ± 0.0
2.812AsnThr: 2.812 ± 0.0
0.937AsnVal: 0.937 ± 0.0
0.0AsnTrp: 0.0 ± 0.0
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
0.937ProAla: 0.937 ± 0.0
0.0ProCys: 0.0 ± 0.0
3.749ProAsp: 3.749 ± 0.0
5.623ProGlu: 5.623 ± 0.0
2.812ProPhe: 2.812 ± 0.0
3.749ProGly: 3.749 ± 0.0
0.0ProHis: 0.0 ± 0.0
2.812ProIle: 2.812 ± 0.0
0.0ProLys: 0.0 ± 0.0
7.498ProLeu: 7.498 ± 0.0
0.937ProMet: 0.937 ± 0.0
2.812ProAsn: 2.812 ± 0.0
2.812ProPro: 2.812 ± 0.0
4.686ProGln: 4.686 ± 0.0
7.498ProArg: 7.498 ± 0.0
3.749ProSer: 3.749 ± 0.0
1.874ProThr: 1.874 ± 0.0
4.686ProVal: 4.686 ± 0.0
0.0ProTrp: 0.0 ± 0.0
2.812ProTyr: 2.812 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.812GlnAla: 2.812 ± 0.0
0.937GlnCys: 0.937 ± 0.0
2.812GlnAsp: 2.812 ± 0.0
1.874GlnGlu: 1.874 ± 0.0
1.874GlnPhe: 1.874 ± 0.0
0.937GlnGly: 0.937 ± 0.0
0.0GlnHis: 0.0 ± 0.0
0.937GlnIle: 0.937 ± 0.0
1.874GlnLys: 1.874 ± 0.0
1.874GlnLeu: 1.874 ± 0.0
1.874GlnMet: 1.874 ± 0.0
2.812GlnAsn: 2.812 ± 0.0
0.937GlnPro: 0.937 ± 0.0
0.937GlnGln: 0.937 ± 0.0
1.874GlnArg: 1.874 ± 0.0
2.812GlnSer: 2.812 ± 0.0
1.874GlnThr: 1.874 ± 0.0
0.937GlnVal: 0.937 ± 0.0
0.937GlnTrp: 0.937 ± 0.0
2.812GlnTyr: 2.812 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
6.56ArgAla: 6.56 ± 0.0
0.937ArgCys: 0.937 ± 0.0
4.686ArgAsp: 4.686 ± 0.0
3.749ArgGlu: 3.749 ± 0.0
5.623ArgPhe: 5.623 ± 0.0
4.686ArgGly: 4.686 ± 0.0
3.749ArgHis: 3.749 ± 0.0
2.812ArgIle: 2.812 ± 0.0
4.686ArgLys: 4.686 ± 0.0
6.56ArgLeu: 6.56 ± 0.0
5.623ArgMet: 5.623 ± 0.0
0.937ArgAsn: 0.937 ± 0.0
3.749ArgPro: 3.749 ± 0.0
2.812ArgGln: 2.812 ± 0.0
7.498ArgArg: 7.498 ± 0.0
9.372ArgSer: 9.372 ± 0.0
5.623ArgThr: 5.623 ± 0.0
3.749ArgVal: 3.749 ± 0.0
4.686ArgTrp: 4.686 ± 0.0
2.812ArgTyr: 2.812 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
2.812SerAla: 2.812 ± 0.0
1.874SerCys: 1.874 ± 0.0
6.56SerAsp: 6.56 ± 0.0
0.0SerGlu: 0.0 ± 0.0
3.749SerPhe: 3.749 ± 0.0
5.623SerGly: 5.623 ± 0.0
1.874SerHis: 1.874 ± 0.0
3.749SerIle: 3.749 ± 0.0
2.812SerLys: 2.812 ± 0.0
3.749SerLeu: 3.749 ± 0.0
0.937SerMet: 0.937 ± 0.0
5.623SerAsn: 5.623 ± 0.0
3.749SerPro: 3.749 ± 0.0
0.937SerGln: 0.937 ± 0.0
7.498SerArg: 7.498 ± 0.0
7.498SerSer: 7.498 ± 0.0
1.874SerThr: 1.874 ± 0.0
11.246SerVal: 11.246 ± 0.0
1.874SerTrp: 1.874 ± 0.0
1.874SerTyr: 1.874 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
5.623ThrAla: 5.623 ± 0.0
1.874ThrCys: 1.874 ± 0.0
2.812ThrAsp: 2.812 ± 0.0
2.812ThrGlu: 2.812 ± 0.0
3.749ThrPhe: 3.749 ± 0.0
3.749ThrGly: 3.749 ± 0.0
0.937ThrHis: 0.937 ± 0.0
4.686ThrIle: 4.686 ± 0.0
4.686ThrLys: 4.686 ± 0.0
5.623ThrLeu: 5.623 ± 0.0
0.937ThrMet: 0.937 ± 0.0
0.937ThrAsn: 0.937 ± 0.0
1.874ThrPro: 1.874 ± 0.0
3.749ThrGln: 3.749 ± 0.0
3.749ThrArg: 3.749 ± 0.0
3.749ThrSer: 3.749 ± 0.0
5.623ThrThr: 5.623 ± 0.0
3.749ThrVal: 3.749 ± 0.0
0.0ThrTrp: 0.0 ± 0.0
2.812ThrTyr: 2.812 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
2.812ValAla: 2.812 ± 0.0
0.937ValCys: 0.937 ± 0.0
2.812ValAsp: 2.812 ± 0.0
2.812ValGlu: 2.812 ± 0.0
1.874ValPhe: 1.874 ± 0.0
5.623ValGly: 5.623 ± 0.0
0.0ValHis: 0.0 ± 0.0
4.686ValIle: 4.686 ± 0.0
0.937ValLys: 0.937 ± 0.0
7.498ValLeu: 7.498 ± 0.0
2.812ValMet: 2.812 ± 0.0
2.812ValAsn: 2.812 ± 0.0
5.623ValPro: 5.623 ± 0.0
0.937ValGln: 0.937 ± 0.0
4.686ValArg: 4.686 ± 0.0
2.812ValSer: 2.812 ± 0.0
4.686ValThr: 4.686 ± 0.0
7.498ValVal: 7.498 ± 0.0
1.874ValTrp: 1.874 ± 0.0
0.937ValTyr: 0.937 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.937TrpAla: 0.937 ± 0.0
0.937TrpCys: 0.937 ± 0.0
1.874TrpAsp: 1.874 ± 0.0
0.937TrpGlu: 0.937 ± 0.0
1.874TrpPhe: 1.874 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.937TrpIle: 0.937 ± 0.0
0.937TrpLys: 0.937 ± 0.0
0.937TrpLeu: 0.937 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.937TrpPro: 0.937 ± 0.0
0.0TrpGln: 0.0 ± 0.0
2.812TrpArg: 2.812 ± 0.0
3.749TrpSer: 3.749 ± 0.0
0.937TrpThr: 0.937 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.937TrpTrp: 0.937 ± 0.0
0.937TrpTyr: 0.937 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.749TyrAla: 3.749 ± 0.0
1.874TyrCys: 1.874 ± 0.0
2.812TyrAsp: 2.812 ± 0.0
1.874TyrGlu: 1.874 ± 0.0
0.937TyrPhe: 0.937 ± 0.0
0.0TyrGly: 0.0 ± 0.0
0.937TyrHis: 0.937 ± 0.0
1.874TyrIle: 1.874 ± 0.0
0.937TyrLys: 0.937 ± 0.0
5.623TyrLeu: 5.623 ± 0.0
1.874TyrMet: 1.874 ± 0.0
0.937TyrAsn: 0.937 ± 0.0
0.937TyrPro: 0.937 ± 0.0
3.749TyrGln: 3.749 ± 0.0
3.749TyrArg: 3.749 ± 0.0
2.812TyrSer: 2.812 ± 0.0
1.874TyrThr: 1.874 ± 0.0
1.874TyrVal: 1.874 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
0.937TyrTyr: 0.937 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (1068 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski