Amino acid dipepetide frequency for Leminorella grimontii ATCC 33999 = DSM 5078

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.786AlaAla: 9.786 ± 0.124	1.137AlaCys: 1.137 ± 0.035	4.963AlaAsp: 4.963 ± 0.064	5.685AlaGlu: 5.685 ± 0.077	3.782AlaPhe: 3.782 ± 0.061	7.449AlaGly: 7.449 ± 0.114	1.585AlaHis: 1.585 ± 0.039	5.762AlaIle: 5.762 ± 0.09	4.369AlaLys: 4.369 ± 0.068	11.526AlaLeu: 11.526 ± 0.12	2.777AlaMet: 2.777 ± 0.054	3.403AlaAsn: 3.403 ± 0.069	3.575AlaPro: 3.575 ± 0.067	4.241AlaGln: 4.241 ± 0.071	4.921AlaArg: 4.921 ± 0.075	5.918AlaSer: 5.918 ± 0.081	4.657AlaThr: 4.657 ± 0.087	6.875AlaVal: 6.875 ± 0.084	1.232AlaTrp: 1.232 ± 0.033	2.586AlaTyr: 2.586 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	0.987CysAla: 0.987 ± 0.031	0.186CysCys: 0.186 ± 0.014	0.614CysAsp: 0.614 ± 0.024	0.574CysGlu: 0.574 ± 0.023	0.399CysPhe: 0.399 ± 0.019	1.088CysGly: 1.088 ± 0.033	0.326CysHis: 0.326 ± 0.021	0.604CysIle: 0.604 ± 0.028	0.371CysLys: 0.371 ± 0.02	1.005CysLeu: 1.005 ± 0.031	0.232CysMet: 0.232 ± 0.017	0.324CysAsn: 0.324 ± 0.018	0.506CysPro: 0.506 ± 0.024	0.439CysGln: 0.439 ± 0.018	0.706CysArg: 0.706 ± 0.027	0.673CysSer: 0.673 ± 0.024	0.483CysThr: 0.483 ± 0.023	0.784CysVal: 0.784 ± 0.029	0.167CysTrp: 0.167 ± 0.012	0.32CysTyr: 0.32 ± 0.019	0.0CysXaa: 0.0 ± 0.0
Asp	5.541AspAla: 5.541 ± 0.082	0.568AspCys: 0.568 ± 0.023	3.044AspAsp: 3.044 ± 0.065	3.65AspGlu: 3.65 ± 0.067	2.071AspPhe: 2.071 ± 0.041	4.685AspGly: 4.685 ± 0.092	0.787AspHis: 0.787 ± 0.026	3.457AspIle: 3.457 ± 0.064	2.595AspLys: 2.595 ± 0.052	4.55AspLeu: 4.55 ± 0.072	1.363AspMet: 1.363 ± 0.031	2.163AspAsn: 2.163 ± 0.047	2.051AspPro: 2.051 ± 0.043	1.052AspGln: 1.052 ± 0.031	2.956AspArg: 2.956 ± 0.056	3.244AspSer: 3.244 ± 0.071	2.457AspThr: 2.457 ± 0.053	4.341AspVal: 4.341 ± 0.07	0.796AspTrp: 0.796 ± 0.026	2.067AspTyr: 2.067 ± 0.043	0.0AspXaa: 0.0 ± 0.0
Glu	5.309GluAla: 5.309 ± 0.077	0.521GluCys: 0.521 ± 0.023	2.467GluAsp: 2.467 ± 0.054	3.643GluGlu: 3.643 ± 0.079	1.89GluPhe: 1.89 ± 0.039	4.005GluGly: 4.005 ± 0.062	1.247GluHis: 1.247 ± 0.036	3.282GluIle: 3.282 ± 0.053	3.478GluLys: 3.478 ± 0.065	6.068GluLeu: 6.068 ± 0.091	1.684GluMet: 1.684 ± 0.037	2.392GluAsn: 2.392 ± 0.046	2.171GluPro: 2.171 ± 0.052	3.234GluGln: 3.234 ± 0.055	4.282GluArg: 4.282 ± 0.072	3.385GluSer: 3.385 ± 0.056	2.79GluThr: 2.79 ± 0.05	3.657GluVal: 3.657 ± 0.065	0.798GluTrp: 0.798 ± 0.03	1.476GluTyr: 1.476 ± 0.04	0.0GluXaa: 0.0 ± 0.0
Phe	3.227PheAla: 3.227 ± 0.06	0.55PheCys: 0.55 ± 0.024	2.376PheAsp: 2.376 ± 0.047	1.786PheGlu: 1.786 ± 0.041	1.678PhePhe: 1.678 ± 0.051	3.245PheGly: 3.245 ± 0.062	0.756PheHis: 0.756 ± 0.024	2.815PheIle: 2.815 ± 0.059	1.444PheLys: 1.444 ± 0.035	3.244PheLeu: 3.244 ± 0.063	0.981PheMet: 0.981 ± 0.029	1.756PheAsn: 1.756 ± 0.037	1.438PhePro: 1.438 ± 0.038	1.031PheGln: 1.031 ± 0.029	1.662PheArg: 1.662 ± 0.039	3.343PheSer: 3.343 ± 0.058	2.368PheThr: 2.368 ± 0.048	2.436PheVal: 2.436 ± 0.044	0.565PheTrp: 0.565 ± 0.024	1.287PheTyr: 1.287 ± 0.032	0.0PheXaa: 0.0 ± 0.0
Gly	7.175GlyAla: 7.175 ± 0.118	1.03GlyCys: 1.03 ± 0.031	4.25GlyAsp: 4.25 ± 0.083	4.743GlyGlu: 4.743 ± 0.065	3.278GlyPhe: 3.278 ± 0.054	6.423GlyGly: 6.423 ± 0.149	1.563GlyHis: 1.563 ± 0.044	5.235GlyIle: 5.235 ± 0.075	4.13GlyLys: 4.13 ± 0.06	7.7GlyLeu: 7.7 ± 0.092	2.297GlyMet: 2.297 ± 0.05	3.071GlyAsn: 3.071 ± 0.088	1.945GlyPro: 1.945 ± 0.044	3.019GlyGln: 3.019 ± 0.059	3.854GlyArg: 3.854 ± 0.062	5.291GlySer: 5.291 ± 0.129	4.095GlyThr: 4.095 ± 0.109	6.202GlyVal: 6.202 ± 0.084	1.212GlyTrp: 1.212 ± 0.033	2.955GlyTyr: 2.955 ± 0.063	0.0GlyXaa: 0.0 ± 0.0
His	1.626HisAla: 1.626 ± 0.034	0.274HisCys: 0.274 ± 0.017	0.995HisAsp: 0.995 ± 0.029	0.957HisGlu: 0.957 ± 0.033	0.858HisPhe: 0.858 ± 0.03	1.6HisGly: 1.6 ± 0.051	0.603HisHis: 0.603 ± 0.029	1.155HisIle: 1.155 ± 0.032	0.684HisLys: 0.684 ± 0.027	1.895HisLeu: 1.895 ± 0.048	0.502HisMet: 0.502 ± 0.021	0.685HisAsn: 0.685 ± 0.024	1.158HisPro: 1.158 ± 0.032	0.956HisGln: 0.956 ± 0.031	1.299HisArg: 1.299 ± 0.034	1.183HisSer: 1.183 ± 0.035	0.939HisThr: 0.939 ± 0.028	1.239HisVal: 1.239 ± 0.034	0.319HisTrp: 0.319 ± 0.015	0.78HisTyr: 0.78 ± 0.03	0.0HisXaa: 0.0 ± 0.0
Ile	6.36IleAla: 6.36 ± 0.079	0.603IleCys: 0.603 ± 0.022	3.739IleAsp: 3.739 ± 0.059	3.689IleGlu: 3.689 ± 0.065	1.982IlePhe: 1.982 ± 0.051	4.983IleGly: 4.983 ± 0.069	1.105IleHis: 1.105 ± 0.032	3.134IleIle: 3.134 ± 0.061	2.597IleLys: 2.597 ± 0.049	4.837IleLeu: 4.837 ± 0.084	1.261IleMet: 1.261 ± 0.035	2.645IleAsn: 2.645 ± 0.052	2.653IlePro: 2.653 ± 0.05	1.793IleGln: 1.793 ± 0.043	2.872IleArg: 2.872 ± 0.047	4.01IleSer: 4.01 ± 0.062	3.471IleThr: 3.471 ± 0.07	4.428IleVal: 4.428 ± 0.071	0.572IleTrp: 0.572 ± 0.025	1.646IleTyr: 1.646 ± 0.041	0.0IleXaa: 0.0 ± 0.0
Lys	4.566LysAla: 4.566 ± 0.084	0.275LysCys: 0.275 ± 0.016	2.406LysAsp: 2.406 ± 0.061	2.941LysGlu: 2.941 ± 0.061	1.141LysPhe: 1.141 ± 0.032	3.433LysGly: 3.433 ± 0.063	0.77LysHis: 0.77 ± 0.026	2.464LysIle: 2.464 ± 0.047	2.523LysLys: 2.523 ± 0.056	4.008LysLeu: 4.008 ± 0.067	1.351LysMet: 1.351 ± 0.037	1.921LysAsn: 1.921 ± 0.045	2.086LysPro: 2.086 ± 0.046	1.954LysGln: 1.954 ± 0.039	2.829LysArg: 2.829 ± 0.053	2.714LysSer: 2.714 ± 0.053	2.638LysThr: 2.638 ± 0.045	3.156LysVal: 3.156 ± 0.061	0.424LysTrp: 0.424 ± 0.018	1.179LysTyr: 1.179 ± 0.036	0.0LysXaa: 0.0 ± 0.0
Leu	10.632LeuAla: 10.632 ± 0.113	1.246LeuCys: 1.246 ± 0.035	5.387LeuAsp: 5.387 ± 0.078	5.392LeuGlu: 5.392 ± 0.074	4.267LeuPhe: 4.267 ± 0.074	7.512LeuGly: 7.512 ± 0.092	1.926LeuHis: 1.926 ± 0.045	6.039LeuIle: 6.039 ± 0.085	4.787LeuLys: 4.787 ± 0.067	11.067LeuLeu: 11.067 ± 0.162	2.771LeuMet: 2.771 ± 0.056	4.293LeuAsn: 4.293 ± 0.071	5.183LeuPro: 5.183 ± 0.072	3.404LeuGln: 3.404 ± 0.052	5.41LeuArg: 5.41 ± 0.081	8.043LeuSer: 8.043 ± 0.095	6.549LeuThr: 6.549 ± 0.106	6.618LeuVal: 6.618 ± 0.073	1.241LeuTrp: 1.241 ± 0.037	2.815LeuTyr: 2.815 ± 0.05	0.0LeuXaa: 0.0 ± 0.0
Met	2.762MetAla: 2.762 ± 0.054	0.181MetCys: 0.181 ± 0.012	1.266MetAsp: 1.266 ± 0.033	1.235MetGlu: 1.235 ± 0.031	0.864MetPhe: 0.864 ± 0.035	1.983MetGly: 1.983 ± 0.045	0.46MetHis: 0.46 ± 0.021	1.303MetIle: 1.303 ± 0.033	1.488MetLys: 1.488 ± 0.037	2.919MetLeu: 2.919 ± 0.06	0.9MetMet: 0.9 ± 0.028	1.155MetAsn: 1.155 ± 0.03	1.297MetPro: 1.297 ± 0.037	1.009MetGln: 1.009 ± 0.027	1.397MetArg: 1.397 ± 0.035	1.858MetSer: 1.858 ± 0.043	1.806MetThr: 1.806 ± 0.041	1.766MetVal: 1.766 ± 0.041	0.215MetTrp: 0.215 ± 0.014	0.569MetTyr: 0.569 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	4.034AsnAla: 4.034 ± 0.088	0.322AsnCys: 0.322 ± 0.017	2.18AsnAsp: 2.18 ± 0.046	1.935AsnGlu: 1.935 ± 0.043	1.221AsnPhe: 1.221 ± 0.032	3.804AsnGly: 3.804 ± 0.109	0.784AsnHis: 0.784 ± 0.022	2.135AsnIle: 2.135 ± 0.05	1.575AsnLys: 1.575 ± 0.038	3.466AsnLeu: 3.466 ± 0.064	0.925AsnMet: 0.925 ± 0.027	1.65AsnAsn: 1.65 ± 0.056	1.963AsnPro: 1.963 ± 0.047	1.544AsnGln: 1.544 ± 0.038	2.099AsnArg: 2.099 ± 0.037	2.322AsnSer: 2.322 ± 0.073	1.92AsnThr: 1.92 ± 0.054	3.124AsnVal: 3.124 ± 0.062	0.509AsnTrp: 0.509 ± 0.022	1.202AsnTyr: 1.202 ± 0.037	0.0AsnXaa: 0.0 ± 0.0
Pro	3.805ProAla: 3.805 ± 0.06	0.39ProCys: 0.39 ± 0.018	2.578ProAsp: 2.578 ± 0.056	3.415ProGlu: 3.415 ± 0.063	1.798ProPhe: 1.798 ± 0.043	2.927ProGly: 2.927 ± 0.049	0.905ProHis: 0.905 ± 0.029	2.174ProIle: 2.174 ± 0.044	1.729ProLys: 1.729 ± 0.039	4.685ProLeu: 4.685 ± 0.079	1.144ProMet: 1.144 ± 0.03	1.432ProAsn: 1.432 ± 0.036	1.502ProPro: 1.502 ± 0.042	1.859ProGln: 1.859 ± 0.045	1.677ProArg: 1.677 ± 0.043	2.555ProSer: 2.555 ± 0.05	2.339ProThr: 2.339 ± 0.05	3.379ProVal: 3.379 ± 0.059	0.578ProTrp: 0.578 ± 0.022	1.332ProTyr: 1.332 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	4.213GlnAla: 4.213 ± 0.078	0.352GlnCys: 0.352 ± 0.018	1.814GlnAsp: 1.814 ± 0.04	2.27GlnGlu: 2.27 ± 0.047	1.323GlnPhe: 1.323 ± 0.034	3.002GlnGly: 3.002 ± 0.055	0.863GlnHis: 0.863 ± 0.026	2.151GlnIle: 2.151 ± 0.048	1.885GlnLys: 1.885 ± 0.039	4.163GlnLeu: 4.163 ± 0.067	1.003GlnMet: 1.003 ± 0.03	1.437GlnAsn: 1.437 ± 0.036	1.739GlnPro: 1.739 ± 0.041	2.3GlnGln: 2.3 ± 0.06	2.788GlnArg: 2.788 ± 0.056	2.427GlnSer: 2.427 ± 0.047	2.077GlnThr: 2.077 ± 0.046	2.602GlnVal: 2.602 ± 0.048	0.596GlnTrp: 0.596 ± 0.023	1.129GlnTyr: 1.129 ± 0.03	0.0GlnXaa: 0.0 ± 0.0
Arg	4.449ArgAla: 4.449 ± 0.065	0.611ArgCys: 0.611 ± 0.028	2.809ArgAsp: 2.809 ± 0.051	3.541ArgGlu: 3.541 ± 0.07	2.603ArgPhe: 2.603 ± 0.05	3.39ArgGly: 3.39 ± 0.059	1.294ArgHis: 1.294 ± 0.035	3.409ArgIle: 3.409 ± 0.061	2.18ArgLys: 2.18 ± 0.051	6.866ArgLeu: 6.866 ± 0.092	1.461ArgMet: 1.461 ± 0.034	1.801ArgAsn: 1.801 ± 0.036	2.208ArgPro: 2.208 ± 0.042	2.776ArgGln: 2.776 ± 0.054	3.518ArgArg: 3.518 ± 0.078	2.915ArgSer: 2.915 ± 0.049	2.343ArgThr: 2.343 ± 0.046	3.788ArgVal: 3.788 ± 0.058	0.922ArgTrp: 0.922 ± 0.026	2.232ArgTyr: 2.232 ± 0.051	0.0ArgXaa: 0.0 ± 0.0
Ser	6.476SerAla: 6.476 ± 0.09	0.636SerCys: 0.636 ± 0.027	3.466SerAsp: 3.466 ± 0.059	3.471SerGlu: 3.471 ± 0.058	2.444SerPhe: 2.444 ± 0.048	6.483SerGly: 6.483 ± 0.156	1.387SerHis: 1.387 ± 0.037	3.388SerIle: 3.388 ± 0.064	2.206SerLys: 2.206 ± 0.052	7.401SerLeu: 7.401 ± 0.091	1.5SerMet: 1.5 ± 0.035	2.132SerAsn: 2.132 ± 0.05	2.842SerPro: 2.842 ± 0.062	2.714SerGln: 2.714 ± 0.05	3.454SerArg: 3.454 ± 0.05	4.353SerSer: 4.353 ± 0.09	3.32SerThr: 3.32 ± 0.08	4.782SerVal: 4.782 ± 0.079	0.943SerTrp: 0.943 ± 0.031	1.95SerTyr: 1.95 ± 0.039	0.0SerXaa: 0.0 ± 0.0
Thr	4.918ThrAla: 4.918 ± 0.081	0.48ThrCys: 0.48 ± 0.022	2.705ThrAsp: 2.705 ± 0.049	2.698ThrGlu: 2.698 ± 0.048	1.964ThrPhe: 1.964 ± 0.042	4.631ThrGly: 4.631 ± 0.11	1.085ThrHis: 1.085 ± 0.034	3.113ThrIle: 3.113 ± 0.069	1.778ThrLys: 1.778 ± 0.045	7.118ThrLeu: 7.118 ± 0.106	1.175ThrMet: 1.175 ± 0.035	1.762ThrAsn: 1.762 ± 0.058	3.06ThrPro: 3.06 ± 0.06	2.009ThrGln: 2.009 ± 0.046	2.578ThrArg: 2.578 ± 0.043	3.129ThrSer: 3.129 ± 0.066	2.854ThrThr: 2.854 ± 0.077	4.371ThrVal: 4.371 ± 0.087	0.627ThrTrp: 0.627 ± 0.022	1.4ThrTyr: 1.4 ± 0.041	0.0ThrXaa: 0.0 ± 0.0
Val	6.738ValAla: 6.738 ± 0.084	0.847ValCys: 0.847 ± 0.033	4.095ValAsp: 4.095 ± 0.068	4.274ValGlu: 4.274 ± 0.073	2.538ValPhe: 2.538 ± 0.049	5.451ValGly: 5.451 ± 0.071	1.225ValHis: 1.225 ± 0.033	4.587ValIle: 4.587 ± 0.069	3.412ValLys: 3.412 ± 0.06	6.834ValLeu: 6.834 ± 0.093	2.07ValMet: 2.07 ± 0.048	3.172ValAsn: 3.172 ± 0.074	2.756ValPro: 2.756 ± 0.053	2.296ValGln: 2.296 ± 0.053	3.602ValArg: 3.602 ± 0.055	5.078ValSer: 5.078 ± 0.075	4.394ValThr: 4.394 ± 0.078	5.452ValVal: 5.452 ± 0.09	0.948ValTrp: 0.948 ± 0.029	1.993ValTyr: 1.993 ± 0.04	0.0ValXaa: 0.0 ± 0.0
Trp	0.957TrpAla: 0.957 ± 0.029	0.161TrpCys: 0.161 ± 0.011	0.586TrpAsp: 0.586 ± 0.023	0.551TrpGlu: 0.551 ± 0.021	0.617TrpPhe: 0.617 ± 0.026	0.853TrpGly: 0.853 ± 0.031	0.343TrpHis: 0.343 ± 0.017	0.725TrpIle: 0.725 ± 0.026	0.51TrpLys: 0.51 ± 0.022	1.993TrpLeu: 1.993 ± 0.052	0.411TrpMet: 0.411 ± 0.018	0.475TrpAsn: 0.475 ± 0.02	0.602TrpPro: 0.602 ± 0.029	0.882TrpGln: 0.882 ± 0.029	0.935TrpArg: 0.935 ± 0.03	0.784TrpSer: 0.784 ± 0.03	0.517TrpThr: 0.517 ± 0.02	0.803TrpVal: 0.803 ± 0.031	0.225TrpTrp: 0.225 ± 0.017	0.423TrpTyr: 0.423 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.668TyrAla: 2.668 ± 0.047	0.418TyrCys: 0.418 ± 0.019	1.697TyrAsp: 1.697 ± 0.041	1.326TyrGlu: 1.326 ± 0.029	1.27TyrPhe: 1.27 ± 0.037	2.523TyrGly: 2.523 ± 0.053	0.692TyrHis: 0.692 ± 0.025	1.445TyrIle: 1.445 ± 0.035	1.039TyrLys: 1.039 ± 0.033	3.238TyrLeu: 3.238 ± 0.055	0.625TyrMet: 0.625 ± 0.026	1.045TyrAsn: 1.045 ± 0.033	1.47TyrPro: 1.47 ± 0.037	1.621TyrGln: 1.621 ± 0.042	2.277TyrArg: 2.277 ± 0.049	2.123TyrSer: 2.123 ± 0.051	1.438TyrThr: 1.438 ± 0.043	1.959TyrVal: 1.959 ± 0.044	0.467TyrTrp: 0.467 ± 0.022	1.008TyrTyr: 1.008 ± 0.034	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3756 proteins (1211632 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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