Amino acid dipepetide frequency for Acinonyx jubatus (Cheetah)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.092AlaAla: 7.092 ± 0.032	1.345AlaCys: 1.345 ± 0.009	3.026AlaAsp: 3.026 ± 0.012	4.983AlaGlu: 4.983 ± 0.023	2.478AlaPhe: 2.478 ± 0.012	4.9AlaGly: 4.9 ± 0.025	1.559AlaHis: 1.559 ± 0.008	2.623AlaIle: 2.623 ± 0.011	3.517AlaLys: 3.517 ± 0.022	7.117AlaLeu: 7.117 ± 0.02	1.444AlaMet: 1.444 ± 0.007	1.994AlaAsn: 1.994 ± 0.008	4.463AlaPro: 4.463 ± 0.026	3.43AlaGln: 3.43 ± 0.015	3.913AlaArg: 3.913 ± 0.015	6.056AlaSer: 6.056 ± 0.019	3.607AlaThr: 3.607 ± 0.014	4.613AlaVal: 4.613 ± 0.014	0.773AlaTrp: 0.773 ± 0.006	1.463AlaTyr: 1.463 ± 0.008	0.002AlaXaa: 0.002 ± 0.0
Cys	1.22CysAla: 1.22 ± 0.009	0.546CysCys: 0.546 ± 0.007	0.987CysAsp: 0.987 ± 0.008	1.257CysGlu: 1.257 ± 0.011	0.773CysPhe: 0.773 ± 0.005	1.642CysGly: 1.642 ± 0.013	0.64CysHis: 0.64 ± 0.006	0.884CysIle: 0.884 ± 0.008	1.074CysLys: 1.074 ± 0.008	2.04CysLeu: 2.04 ± 0.011	0.374CysMet: 0.374 ± 0.003	0.758CysAsn: 0.758 ± 0.006	1.343CysPro: 1.343 ± 0.01	1.04CysGln: 1.04 ± 0.009	1.243CysArg: 1.243 ± 0.008	1.918CysSer: 1.918 ± 0.011	1.008CysThr: 1.008 ± 0.008	1.248CysVal: 1.248 ± 0.009	0.26CysTrp: 0.26 ± 0.004	0.528CysTyr: 0.528 ± 0.004	0.001CysXaa: 0.001 ± 0.0
Asp	2.949AspAla: 2.949 ± 0.013	1.021AspCys: 1.021 ± 0.008	2.681AspAsp: 2.681 ± 0.013	3.492AspGlu: 3.492 ± 0.013	2.052AspPhe: 2.052 ± 0.01	3.358AspGly: 3.358 ± 0.017	1.148AspHis: 1.148 ± 0.006	2.524AspIle: 2.524 ± 0.01	2.526AspLys: 2.526 ± 0.01	5.041AspLeu: 5.041 ± 0.015	1.103AspMet: 1.103 ± 0.006	1.632AspAsn: 1.632 ± 0.01	2.97AspPro: 2.97 ± 0.011	1.878AspGln: 1.878 ± 0.009	2.51AspArg: 2.51 ± 0.01	4.304AspSer: 4.304 ± 0.014	2.548AspThr: 2.548 ± 0.01	3.087AspVal: 3.087 ± 0.013	0.588AspTrp: 0.588 ± 0.005	1.455AspTyr: 1.455 ± 0.009	0.002AspXaa: 0.002 ± 0.0
Glu	5.445GluAla: 5.445 ± 0.02	1.39GluCys: 1.39 ± 0.014	4.519GluAsp: 4.519 ± 0.014	8.313GluGlu: 8.313 ± 0.038	1.952GluPhe: 1.952 ± 0.008	4.367GluGly: 4.367 ± 0.014	1.532GluHis: 1.532 ± 0.008	3.144GluIle: 3.144 ± 0.016	5.57GluLys: 5.57 ± 0.027	6.638GluLeu: 6.638 ± 0.029	1.655GluMet: 1.655 ± 0.009	3.142GluAsn: 3.142 ± 0.014	3.473GluPro: 3.473 ± 0.017	3.361GluGln: 3.361 ± 0.017	4.29GluArg: 4.29 ± 0.019	4.671GluSer: 4.671 ± 0.017	3.508GluThr: 3.508 ± 0.012	4.263GluVal: 4.263 ± 0.015	0.682GluTrp: 0.682 ± 0.005	1.568GluTyr: 1.568 ± 0.011	0.002GluXaa: 0.002 ± 0.0
Phe	1.873PheAla: 1.873 ± 0.009	0.85PheCys: 0.85 ± 0.006	1.575PheAsp: 1.575 ± 0.008	1.941PheGlu: 1.941 ± 0.009	1.453PhePhe: 1.453 ± 0.007	2.056PheGly: 2.056 ± 0.011	0.993PheHis: 0.993 ± 0.006	1.695PheIle: 1.695 ± 0.011	1.653PheLys: 1.653 ± 0.008	3.787PheLeu: 3.787 ± 0.013	0.723PheMet: 0.723 ± 0.005	1.246PheAsn: 1.246 ± 0.008	1.963PhePro: 1.963 ± 0.01	1.738PheGln: 1.738 ± 0.008	1.906PheArg: 1.906 ± 0.011	3.269PheSer: 3.269 ± 0.013	1.928PheThr: 1.928 ± 0.011	1.991PheVal: 1.991 ± 0.011	0.448PheTrp: 0.448 ± 0.004	1.08PheTyr: 1.08 ± 0.006	0.002PheXaa: 0.002 ± 0.0
Gly	4.687GlyAla: 4.687 ± 0.021	1.228GlyCys: 1.228 ± 0.008	3.162GlyAsp: 3.162 ± 0.015	4.23GlyGlu: 4.23 ± 0.019	2.271GlyPhe: 2.271 ± 0.012	5.222GlyGly: 5.222 ± 0.032	1.732GlyHis: 1.732 ± 0.009	2.6GlyIle: 2.6 ± 0.012	3.704GlyLys: 3.704 ± 0.015	5.838GlyLeu: 5.838 ± 0.02	1.241GlyMet: 1.241 ± 0.007	2.312GlyAsn: 2.312 ± 0.011	4.578GlyPro: 4.578 ± 0.035	2.846GlyGln: 2.846 ± 0.013	3.98GlyArg: 3.98 ± 0.017	5.995GlySer: 5.995 ± 0.024	3.582GlyThr: 3.582 ± 0.015	3.455GlyVal: 3.455 ± 0.017	0.774GlyTrp: 0.774 ± 0.007	1.653GlyTyr: 1.653 ± 0.01	0.002GlyXaa: 0.002 ± 0.0
His	1.372HisAla: 1.372 ± 0.007	0.682HisCys: 0.682 ± 0.005	0.881HisAsp: 0.881 ± 0.005	1.348HisGlu: 1.348 ± 0.007	1.03HisPhe: 1.03 ± 0.006	1.553HisGly: 1.553 ± 0.009	0.948HisHis: 0.948 ± 0.007	1.237HisIle: 1.237 ± 0.007	1.263HisLys: 1.263 ± 0.007	2.928HisLeu: 2.928 ± 0.012	0.564HisMet: 0.564 ± 0.005	0.828HisAsn: 0.828 ± 0.005	1.689HisPro: 1.689 ± 0.009	1.377HisGln: 1.377 ± 0.01	1.645HisArg: 1.645 ± 0.008	2.306HisSer: 2.306 ± 0.01	1.537HisThr: 1.537 ± 0.011	1.52HisVal: 1.52 ± 0.008	0.34HisTrp: 0.34 ± 0.003	0.789HisTyr: 0.789 ± 0.005	0.001HisXaa: 0.001 ± 0.0
Ile	2.481IleAla: 2.481 ± 0.012	0.978IleCys: 0.978 ± 0.006	1.927IleAsp: 1.927 ± 0.01	2.568IleGlu: 2.568 ± 0.014	1.702IlePhe: 1.702 ± 0.01	2.091IleGly: 2.091 ± 0.01	1.301IleHis: 1.301 ± 0.009	2.265IleIle: 2.265 ± 0.014	2.54IleLys: 2.54 ± 0.013	4.31IleLeu: 4.31 ± 0.015	0.934IleMet: 0.934 ± 0.007	1.733IleAsn: 1.733 ± 0.009	2.581IlePro: 2.581 ± 0.012	2.288IleGln: 2.288 ± 0.01	2.313IleArg: 2.313 ± 0.009	3.644IleSer: 3.644 ± 0.013	2.483IleThr: 2.483 ± 0.012	2.357IleVal: 2.357 ± 0.012	0.461IleTrp: 0.461 ± 0.005	1.277IleTyr: 1.277 ± 0.008	0.002IleXaa: 0.002 ± 0.0
Lys	4.033LysAla: 4.033 ± 0.018	1.05LysCys: 1.05 ± 0.008	3.219LysAsp: 3.219 ± 0.014	5.284LysGlu: 5.284 ± 0.027	1.643LysPhe: 1.643 ± 0.008	3.275LysGly: 3.275 ± 0.019	1.417LysHis: 1.417 ± 0.008	2.646LysIle: 2.646 ± 0.011	4.625LysLys: 4.625 ± 0.025	5.132LysLeu: 5.132 ± 0.02	1.402LysMet: 1.402 ± 0.009	2.346LysAsn: 2.346 ± 0.011	3.139LysPro: 3.139 ± 0.016	2.7LysGln: 2.7 ± 0.014	3.277LysArg: 3.277 ± 0.013	4.02LysSer: 4.02 ± 0.018	3.133LysThr: 3.133 ± 0.015	3.392LysVal: 3.392 ± 0.014	0.576LysTrp: 0.576 ± 0.005	1.509LysTyr: 1.509 ± 0.013	0.002LysXaa: 0.002 ± 0.0
Leu	6.724LeuAla: 6.724 ± 0.022	2.084LeuCys: 2.084 ± 0.01	4.746LeuAsp: 4.746 ± 0.014	7.512LeuGlu: 7.512 ± 0.029	3.12LeuPhe: 3.12 ± 0.013	5.744LeuGly: 5.744 ± 0.018	2.763LeuHis: 2.763 ± 0.012	3.637LeuIle: 3.637 ± 0.013	5.772LeuLys: 5.772 ± 0.022	10.496LeuLeu: 10.496 ± 0.032	1.915LeuMet: 1.915 ± 0.009	3.449LeuAsn: 3.449 ± 0.012	6.124LeuPro: 6.124 ± 0.022	5.965LeuGln: 5.965 ± 0.024	6.114LeuArg: 6.114 ± 0.021	8.081LeuSer: 8.081 ± 0.021	4.97LeuThr: 4.97 ± 0.015	5.261LeuVal: 5.261 ± 0.019	1.061LeuTrp: 1.061 ± 0.007	2.408LeuTyr: 2.408 ± 0.013	0.003LeuXaa: 0.003 ± 0.0
Met	1.814MetAla: 1.814 ± 0.009	0.374MetCys: 0.374 ± 0.004	1.219MetAsp: 1.219 ± 0.007	1.84MetGlu: 1.84 ± 0.008	0.688MetPhe: 0.688 ± 0.005	1.227MetGly: 1.227 ± 0.008	0.457MetHis: 0.457 ± 0.003	0.767MetIle: 0.767 ± 0.005	1.401MetLys: 1.401 ± 0.007	1.899MetLeu: 1.899 ± 0.008	0.545MetMet: 0.545 ± 0.005	0.86MetAsn: 0.86 ± 0.005	1.074MetPro: 1.074 ± 0.006	0.927MetGln: 0.927 ± 0.007	1.023MetArg: 1.023 ± 0.006	1.528MetSer: 1.528 ± 0.007	1.083MetThr: 1.083 ± 0.006	1.342MetVal: 1.342 ± 0.006	0.234MetTrp: 0.234 ± 0.003	0.548MetTyr: 0.548 ± 0.004	0.001MetXaa: 0.001 ± 0.0
Asn	2.023AsnAla: 2.023 ± 0.009	0.766AsnCys: 0.766 ± 0.007	1.498AsnAsp: 1.498 ± 0.009	2.172AsnGlu: 2.172 ± 0.011	1.379AsnPhe: 1.379 ± 0.007	2.442AsnGly: 2.442 ± 0.014	0.926AsnHis: 0.926 ± 0.006	2.02AsnIle: 2.02 ± 0.009	2.151AsnLys: 2.151 ± 0.011	3.612AsnLeu: 3.612 ± 0.012	0.862AsnMet: 0.862 ± 0.006	1.449AsnAsn: 1.449 ± 0.008	2.121AsnPro: 2.121 ± 0.011	1.675AsnGln: 1.675 ± 0.009	1.803AsnArg: 1.803 ± 0.008	3.126AsnSer: 3.126 ± 0.013	1.904AsnThr: 1.904 ± 0.01	2.132AsnVal: 2.132 ± 0.01	0.409AsnTrp: 0.409 ± 0.004	1.061AsnTyr: 1.061 ± 0.008	0.001AsnXaa: 0.001 ± 0.0
Pro	5.295ProAla: 5.295 ± 0.028	1.125ProCys: 1.125 ± 0.009	2.896ProAsp: 2.896 ± 0.013	4.674ProGlu: 4.674 ± 0.017	1.868ProPhe: 1.868 ± 0.01	5.713ProGly: 5.713 ± 0.048	1.507ProHis: 1.507 ± 0.009	1.862ProIle: 1.862 ± 0.009	2.84ProLys: 2.84 ± 0.015	5.404ProLeu: 5.404 ± 0.019	1.044ProMet: 1.044 ± 0.007	1.788ProAsn: 1.788 ± 0.009	6.751ProPro: 6.751 ± 0.051	3.007ProGln: 3.007 ± 0.016	3.598ProArg: 3.598 ± 0.019	6.081ProSer: 6.081 ± 0.027	3.21ProThr: 3.21 ± 0.016	3.979ProVal: 3.979 ± 0.016	0.665ProTrp: 0.665 ± 0.005	1.478ProTyr: 1.478 ± 0.009	0.003ProXaa: 0.003 ± 0.0
Gln	3.686GlnAla: 3.686 ± 0.017	0.904GlnCys: 0.904 ± 0.007	2.408GlnAsp: 2.408 ± 0.012	4.122GlnGlu: 4.122 ± 0.02	1.327GlnPhe: 1.327 ± 0.007	2.928GlnGly: 2.928 ± 0.012	1.357GlnHis: 1.357 ± 0.007	2.002GlnIle: 2.002 ± 0.009	3.021GlnLys: 3.021 ± 0.017	4.89GlnLeu: 4.89 ± 0.021	1.111GlnMet: 1.111 ± 0.007	1.845GlnAsn: 1.845 ± 0.01	2.995GlnPro: 2.995 ± 0.015	3.347GlnGln: 3.347 ± 0.028	3.12GlnArg: 3.12 ± 0.014	3.36GlnSer: 3.36 ± 0.014	2.371GlnThr: 2.371 ± 0.011	2.813GlnVal: 2.813 ± 0.012	0.535GlnTrp: 0.535 ± 0.004	1.122GlnTyr: 1.122 ± 0.006	0.002GlnXaa: 0.002 ± 0.0
Arg	4.059ArgAla: 4.059 ± 0.016	1.19ArgCys: 1.19 ± 0.009	2.837ArgAsp: 2.837 ± 0.012	4.248ArgGlu: 4.248 ± 0.017	1.764ArgPhe: 1.764 ± 0.008	3.775ArgGly: 3.775 ± 0.02	1.56ArgHis: 1.56 ± 0.007	2.356ArgIle: 2.356 ± 0.009	3.717ArgLys: 3.717 ± 0.014	5.593ArgLeu: 5.593 ± 0.02	1.172ArgMet: 1.172 ± 0.007	2.087ArgAsn: 2.087 ± 0.01	3.512ArgPro: 3.512 ± 0.017	2.798ArgGln: 2.798 ± 0.015	4.623ArgArg: 4.623 ± 0.021	4.565ArgSer: 4.565 ± 0.022	2.946ArgThr: 2.946 ± 0.012	3.197ArgVal: 3.197 ± 0.014	0.68ArgTrp: 0.68 ± 0.005	1.394ArgTyr: 1.394 ± 0.008	0.002ArgXaa: 0.002 ± 0.0
Ser	5.534SerAla: 5.534 ± 0.019	1.786SerCys: 1.786 ± 0.013	4.057SerAsp: 4.057 ± 0.018	5.482SerGlu: 5.482 ± 0.018	2.932SerPhe: 2.932 ± 0.011	5.751SerGly: 5.751 ± 0.021	2.141SerHis: 2.141 ± 0.011	3.166SerIle: 3.166 ± 0.012	4.154SerLys: 4.154 ± 0.017	8.344SerLeu: 8.344 ± 0.023	1.564SerMet: 1.564 ± 0.008	2.644SerAsn: 2.644 ± 0.011	6.649SerPro: 6.649 ± 0.033	4.021SerGln: 4.021 ± 0.016	4.774SerArg: 4.774 ± 0.021	9.864SerSer: 9.864 ± 0.04	4.585SerThr: 4.585 ± 0.016	4.977SerVal: 4.977 ± 0.016	1.047SerTrp: 1.047 ± 0.008	1.986SerTyr: 1.986 ± 0.008	0.003SerXaa: 0.003 ± 0.0
Thr	3.796ThrAla: 3.796 ± 0.013	1.256ThrCys: 1.256 ± 0.011	2.477ThrAsp: 2.477 ± 0.01	3.697ThrGlu: 3.697 ± 0.015	2.003ThrPhe: 2.003 ± 0.009	3.511ThrGly: 3.511 ± 0.014	1.271ThrHis: 1.271 ± 0.008	2.265ThrIle: 2.265 ± 0.011	2.649ThrLys: 2.649 ± 0.012	5.252ThrLeu: 5.252 ± 0.014	1.081ThrMet: 1.081 ± 0.006	1.647ThrAsn: 1.647 ± 0.009	3.83ThrPro: 3.83 ± 0.018	2.352ThrGln: 2.352 ± 0.01	2.553ThrArg: 2.553 ± 0.011	4.738ThrSer: 4.738 ± 0.018	2.98ThrThr: 2.98 ± 0.018	3.84ThrVal: 3.84 ± 0.016	0.677ThrTrp: 0.677 ± 0.007	1.333ThrTyr: 1.333 ± 0.008	0.002ThrXaa: 0.002 ± 0.0
Val	4.242ValAla: 4.242 ± 0.014	1.362ValCys: 1.362 ± 0.009	2.922ValAsp: 2.922 ± 0.011	3.862ValGlu: 3.862 ± 0.014	2.228ValPhe: 2.228 ± 0.011	3.283ValGly: 3.283 ± 0.015	1.557ValHis: 1.557 ± 0.008	2.734ValIle: 2.734 ± 0.012	3.371ValLys: 3.371 ± 0.015	5.994ValLeu: 5.994 ± 0.017	1.268ValMet: 1.268 ± 0.007	2.231ValAsn: 2.231 ± 0.01	3.786ValPro: 3.786 ± 0.018	2.758ValGln: 2.758 ± 0.011	3.079ValArg: 3.079 ± 0.015	4.952ValSer: 4.952 ± 0.017	3.758ValThr: 3.758 ± 0.017	3.821ValVal: 3.821 ± 0.018	0.673ValTrp: 0.673 ± 0.005	1.529ValTyr: 1.529 ± 0.007	0.002ValXaa: 0.002 ± 0.0
Trp	0.753TrpAla: 0.753 ± 0.005	0.224TrpCys: 0.224 ± 0.003	0.617TrpAsp: 0.617 ± 0.005	0.785TrpGlu: 0.785 ± 0.006	0.409TrpPhe: 0.409 ± 0.004	0.679TrpGly: 0.679 ± 0.007	0.307TrpHis: 0.307 ± 0.003	0.49TrpIle: 0.49 ± 0.005	0.753TrpLys: 0.753 ± 0.006	1.171TrpLeu: 1.171 ± 0.008	0.299TrpMet: 0.299 ± 0.003	0.516TrpAsn: 0.516 ± 0.004	0.529TrpPro: 0.529 ± 0.005	0.53TrpGln: 0.53 ± 0.005	0.714TrpArg: 0.714 ± 0.005	0.849TrpSer: 0.849 ± 0.006	0.656TrpThr: 0.656 ± 0.006	0.632TrpVal: 0.632 ± 0.004	0.173TrpTrp: 0.173 ± 0.003	0.306TrpTyr: 0.306 ± 0.004	0.001TrpXaa: 0.001 ± 0.0
Tyr	1.317TyrAla: 1.317 ± 0.007	0.624TyrCys: 0.624 ± 0.005	1.213TyrAsp: 1.213 ± 0.008	1.672TyrGlu: 1.672 ± 0.01	1.098TyrPhe: 1.098 ± 0.008	1.571TyrGly: 1.571 ± 0.008	0.719TyrHis: 0.719 ± 0.004	1.318TyrIle: 1.318 ± 0.008	1.516TyrLys: 1.516 ± 0.022	2.459TyrLeu: 2.459 ± 0.011	0.548TyrMet: 0.548 ± 0.004	1.025TyrAsn: 1.025 ± 0.007	1.215TyrPro: 1.215 ± 0.008	1.226TyrGln: 1.226 ± 0.007	1.594TyrArg: 1.594 ± 0.01	2.133TyrSer: 2.133 ± 0.009	1.413TyrThr: 1.413 ± 0.01	1.491TyrVal: 1.491 ± 0.007	0.335TyrTrp: 0.335 ± 0.004	0.846TyrTyr: 0.846 ± 0.007	0.001TyrXaa: 0.001 ± 0.0
Xaa	0.002XaaAla: 0.002 ± 0.0	0.001XaaCys: 0.001 ± 0.0	0.001XaaAsp: 0.001 ± 0.0	0.002XaaGlu: 0.002 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.004XaaGly: 0.004 ± 0.0	0.001XaaHis: 0.001 ± 0.0	0.002XaaIle: 0.002 ± 0.0	0.002XaaLys: 0.002 ± 0.0	0.003XaaLeu: 0.003 ± 0.0	0.001XaaMet: 0.001 ± 0.0	0.001XaaAsn: 0.001 ± 0.0	0.003XaaPro: 0.003 ± 0.0	0.002XaaGln: 0.002 ± 0.0	0.002XaaArg: 0.002 ± 0.0	0.002XaaSer: 0.002 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.002XaaVal: 0.002 ± 0.0	0.001XaaTrp: 0.001 ± 0.0	0.001XaaTyr: 0.001 ± 0.0	0.012XaaXaa: 0.012 ± 0.002

Statistics based on 45316 proteins (33444246 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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