Hantaan virus (strain 76-118) (Korean hemorrhagic fever virus)
Average proteome isoelectric point is 6.14
Get precalculated fractions of proteins
Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
All
Note: above files contain also dissociation constants (pKa)
Virtual 2D-PAGE plot for 3 proteins (isoelectric point calculated using IPC2_protein)
Get csv file with sequences according to given criteria:
* You can choose from 21 different methods for calculating isoelectric point
Summary statistics related to proteome-wise predictions
Protein with the lowest isoelectric point:
>sp|P23456|L_HANTV RNA-directed RNA polymerase L OS=Hantaan virus (strain 76-118) OX=11602 GN=L PE=1 SV=3
MM1 pKa = 7.67 GIWKK5 pKa = 8.63 WLVMASLVWPVLTLRR20 pKa = 11.84 NVYY23 pKa = 10.19 DD24 pKa = 3.78 MKK26 pKa = 10.59 IEE28 pKa = 4.44 CPHH31 pKa = 5.59 TVSFGEE37 pKa = 3.96 NSVIGYY43 pKa = 9.52 VEE45 pKa = 4.79 LPPVPLADD53 pKa = 3.62 TAQMVPEE60 pKa = 4.92 SSCNMDD66 pKa = 2.69 NHH68 pKa = 6.31 QSLNTITKK76 pKa = 6.92 YY77 pKa = 8.81 TQVSWRR83 pKa = 11.84 GKK85 pKa = 9.75 ADD87 pKa = 3.44 QSQSSQNSFEE97 pKa = 4.41 TVSTEE102 pKa = 3.43 VDD104 pKa = 3.33 LKK106 pKa = 9.15 GTCVLKK112 pKa = 10.76 HH113 pKa = 6.08 KK114 pKa = 9.84 MVEE117 pKa = 3.45 EE118 pKa = 4.67 SYY120 pKa = 10.78 RR121 pKa = 11.84 SRR123 pKa = 11.84 KK124 pKa = 9.76 SVTCYY129 pKa = 10.73 DD130 pKa = 4.16 LSCNSTYY137 pKa = 10.67 CKK139 pKa = 8.37 PTLYY143 pKa = 10.09 MIVPIHH149 pKa = 6.86 ACNMMKK155 pKa = 10.08 SCLIALGPYY164 pKa = 9.06 RR165 pKa = 11.84 VQVVYY170 pKa = 10.52 EE171 pKa = 4.17 RR172 pKa = 11.84 SYY174 pKa = 11.93 CMTGVLIEE182 pKa = 4.54 GKK184 pKa = 10.3 CFVPDD189 pKa = 3.41 QSVVSIIKK197 pKa = 10.33 HH198 pKa = 5.97 GIFDD202 pKa = 3.7 IASVHH207 pKa = 5.58 IVCFFVAVKK216 pKa = 10.69 GNTYY220 pKa = 10.49 KK221 pKa = 10.48 IFEE224 pKa = 4.2 QVKK227 pKa = 9.6 KK228 pKa = 10.84 SFEE231 pKa = 4.33 STCNDD236 pKa = 3.4 TEE238 pKa = 4.36 NKK240 pKa = 8.28 VQGYY244 pKa = 6.92 YY245 pKa = 9.96 ICIVGGNSAPIYY257 pKa = 10.91 VPTLDD262 pKa = 4.74 DD263 pKa = 3.92 FRR265 pKa = 11.84 SMEE268 pKa = 4.15 AFTGIFRR275 pKa = 11.84 SPHH278 pKa = 6.41 GEE280 pKa = 3.84 DD281 pKa = 3.28 HH282 pKa = 7.31 DD283 pKa = 4.64 LAGEE287 pKa = 4.51 EE288 pKa = 4.01 IASYY292 pKa = 10.79 SIVGPANAKK301 pKa = 9.49 VPHH304 pKa = 6.31 SASSDD309 pKa = 3.64 TLSLIAYY316 pKa = 9.26 SGIPSYY322 pKa = 11.41 SSLSILTSSTEE333 pKa = 3.9 AKK335 pKa = 10.25 HH336 pKa = 5.87 VFSPGLFPKK345 pKa = 10.52 LNHH348 pKa = 5.85 TNCDD352 pKa = 2.91 KK353 pKa = 11.25 SAIPLIWTGMIDD365 pKa = 3.66 LPGYY369 pKa = 9.83 YY370 pKa = 9.59 EE371 pKa = 4.61 AVHH374 pKa = 6.8 PCTVFCVLSGPGASCEE390 pKa = 4.02 AFSEE394 pKa = 4.39 GGIFNITSPMCLVSKK409 pKa = 8.96 QNRR412 pKa = 11.84 FRR414 pKa = 11.84 LTEE417 pKa = 3.66 QQVNFVCQRR426 pKa = 11.84 VDD428 pKa = 2.93 MDD430 pKa = 3.48 IVVYY434 pKa = 10.89 CNGQRR439 pKa = 11.84 KK440 pKa = 9.52 VILTKK445 pKa = 10.2 TLVIGQCIYY454 pKa = 10.71 TITSLFSLLPGVAHH468 pKa = 6.96 SIAVEE473 pKa = 3.89 LCVPGFHH480 pKa = 6.59 GWATAALLVTFCFGWVLIPAITFIILTVLKK510 pKa = 9.68 FIANIFHH517 pKa = 7.07 TSNQEE522 pKa = 3.6 NRR524 pKa = 11.84 LKK526 pKa = 10.93 SVLRR530 pKa = 11.84 KK531 pKa = 9.66 IKK533 pKa = 10.75 EE534 pKa = 4.04 EE535 pKa = 3.91 FEE537 pKa = 4.15 KK538 pKa = 10.52 TKK540 pKa = 10.98 GSMVCDD546 pKa = 3.43 VCKK549 pKa = 10.97 YY550 pKa = 9.33 EE551 pKa = 4.31 CEE553 pKa = 4.26 TYY555 pKa = 10.6 KK556 pKa = 10.42 EE557 pKa = 4.15 LKK559 pKa = 9.85 AHH561 pKa = 6.5 GVSCPQSQCPYY572 pKa = 9.99 CFTHH576 pKa = 7.17 CEE578 pKa = 3.86 PTEE581 pKa = 4.02 AAFQAHH587 pKa = 5.78 YY588 pKa = 10.15 KK589 pKa = 9.07 VCQVTHH595 pKa = 7.24 RR596 pKa = 11.84 FRR598 pKa = 11.84 DD599 pKa = 3.86 DD600 pKa = 3.26 LKK602 pKa = 10.92 KK603 pKa = 9.22 TVTPQNFTPGCYY615 pKa = 7.94 RR616 pKa = 11.84 TLNLFRR622 pKa = 11.84 YY623 pKa = 9.62 KK624 pKa = 10.13 SRR626 pKa = 11.84 CYY628 pKa = 10.25 IFTMWIFLLVLEE640 pKa = 4.98 SILWAASASEE650 pKa = 4.35 TPLTPVWNDD659 pKa = 2.81 NAHH662 pKa = 6.04 GVGSVPMHH670 pKa = 6.9 TDD672 pKa = 3.38 LEE674 pKa = 4.74 LDD676 pKa = 4.08 FSLTSSSKK684 pKa = 7.78 YY685 pKa = 7.56 TYY687 pKa = 9.93 RR688 pKa = 11.84 RR689 pKa = 11.84 KK690 pKa = 8.94 LTNPLEE696 pKa = 4.31 EE697 pKa = 4.29 AQSIDD702 pKa = 3.25 LHH704 pKa = 8.22 IEE706 pKa = 3.63 IEE708 pKa = 4.19 EE709 pKa = 3.92 QTIGVDD715 pKa = 3.61 VHH717 pKa = 7.72 ALGHH721 pKa = 5.93 WFDD724 pKa = 3.78 GRR726 pKa = 11.84 LNLKK730 pKa = 9.26 TSFHH734 pKa = 7.19 CYY736 pKa = 9.2 GACTKK741 pKa = 10.66 YY742 pKa = 10.35 EE743 pKa = 4.4 YY744 pKa = 9.54 PWHH747 pKa = 5.74 TAKK750 pKa = 10.43 CHH752 pKa = 5.01 YY753 pKa = 10.04 EE754 pKa = 3.52 RR755 pKa = 11.84 DD756 pKa = 3.98 YY757 pKa = 11.28 QYY759 pKa = 8.98 EE760 pKa = 4.31 TSWGCNPSDD769 pKa = 4.09 CPGVGTGCTACGLYY783 pKa = 10.31 LDD785 pKa = 3.88 QLKK788 pKa = 10.23 PVGSAYY794 pKa = 9.82 KK795 pKa = 10.1 IITIRR800 pKa = 11.84 YY801 pKa = 6.85 SRR803 pKa = 11.84 RR804 pKa = 11.84 VCVQFGEE811 pKa = 4.33 EE812 pKa = 4.2 NLCKK816 pKa = 10.14 IIDD819 pKa = 3.8 MNDD822 pKa = 3.39 CFVSRR827 pKa = 11.84 HH828 pKa = 4.95 VKK830 pKa = 9.19 VCIIGTVSKK839 pKa = 10.31 FSQGDD844 pKa = 3.47 TLLFFGPLEE853 pKa = 4.46 GGGLIFKK860 pKa = 8.9 HH861 pKa = 5.91 WCTSTCQFGDD871 pKa = 3.7 PGDD874 pKa = 3.65 IMSPRR879 pKa = 11.84 DD880 pKa = 3.48 KK881 pKa = 11.4 GFLCPEE887 pKa = 4.21 FPGSFRR893 pKa = 11.84 KK894 pKa = 9.74 KK895 pKa = 10.43 CNFATTPICEE905 pKa = 4.1 YY906 pKa = 10.3 DD907 pKa = 3.34 GNMVSGYY914 pKa = 9.12 KK915 pKa = 10.03 KK916 pKa = 10.84 VMATIDD922 pKa = 3.57 SFQSFNTSTMHH933 pKa = 5.96 FTDD936 pKa = 5.65 EE937 pKa = 4.43 RR938 pKa = 11.84 IEE940 pKa = 4.09 WKK942 pKa = 10.67 DD943 pKa = 3.21 PDD945 pKa = 3.88 GMLRR949 pKa = 11.84 DD950 pKa = 4.58 HH951 pKa = 7.25 INILVTKK958 pKa = 10.47 DD959 pKa = 2.92 IDD961 pKa = 3.88 FDD963 pKa = 4.09 NLGEE967 pKa = 4.15 NPCKK971 pKa = 10.19 IGLQTSSIEE980 pKa = 4.28 GAWGSGVGFTLTCLVSLTEE999 pKa = 4.65 CPTFLTSIKK1008 pKa = 10.51 ACDD1011 pKa = 3.25 KK1012 pKa = 10.23 AICYY1016 pKa = 9.4 GAEE1019 pKa = 4.18 SVTLTRR1025 pKa = 11.84 GQNTVKK1031 pKa = 10.51 VSGKK1035 pKa = 9.65 GGHH1038 pKa = 6.03 SGSTFRR1044 pKa = 11.84 CCHH1047 pKa = 6.44 GEE1049 pKa = 3.96 DD1050 pKa = 3.89 CSQIGLHH1057 pKa = 6.13 AAAPHH1062 pKa = 6.29 LDD1064 pKa = 3.28 KK1065 pKa = 11.69 VNGISEE1071 pKa = 4.23 IEE1073 pKa = 3.98 NSKK1076 pKa = 10.87 VYY1078 pKa = 10.74 DD1079 pKa = 4.68 DD1080 pKa = 5.12 GAPQCGIKK1088 pKa = 10.16 CWFVKK1093 pKa = 10.08 SGEE1096 pKa = 4.17 WISGIFSGNWIVLIVLCVFLLFSLVLLSILCPVRR1130 pKa = 11.84 KK1131 pKa = 9.36 HH1132 pKa = 6.06 KK1133 pKa = 10.79 KK1134 pKa = 8.64 SS1135 pKa = 3.23
Molecular weight: 126.42 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 5.832
IPC2_protein 6.122
IPC_protein 6.16
Toseland 6.287
ProMoST 6.605
Dawson 6.561
Bjellqvist 6.59
Wikipedia 6.576
Rodwell 6.561
Grimsley 6.364
Solomon 6.561
Lehninger 6.561
Nozaki 6.898
DTASelect 6.985
Thurlkill 7.029
EMBOSS 6.985
Sillero 6.985
Patrickios 1.761
IPC_peptide 6.576
IPC2_peptide 6.839
IPC2.peptide.svr19 6.779
Protein with the highest isoelectric point:
>sp|P23456|L_HANTV RNA-directed RNA polymerase L OS=Hantaan virus (strain 76-118) OX=11602 GN=L PE=1 SV=3
MM1 pKa = 7.85 DD2 pKa = 5.3 KK3 pKa = 10.7 YY4 pKa = 11.11 RR5 pKa = 11.84 EE6 pKa = 3.91 IHH8 pKa = 6.21 NKK10 pKa = 9.93 LKK12 pKa = 10.46 EE13 pKa = 4.11 FSPGTLTAVEE23 pKa = 4.86 CIDD26 pKa = 3.72 YY27 pKa = 10.78 LDD29 pKa = 3.69 RR30 pKa = 11.84 LYY32 pKa = 11.04 AVRR35 pKa = 11.84 HH36 pKa = 6.33 DD37 pKa = 5.02 IVDD40 pKa = 3.44 QMIKK44 pKa = 10.34 HH45 pKa = 6.53 DD46 pKa = 3.55 WSDD49 pKa = 3.45 NKK51 pKa = 10.84 DD52 pKa = 3.38 SEE54 pKa = 4.27 EE55 pKa = 4.75 AIGKK59 pKa = 9.05 VLLFAGVPSNIITALEE75 pKa = 3.84 KK76 pKa = 10.64 KK77 pKa = 10.13 IIPNHH82 pKa = 5.47 PTGKK86 pKa = 9.6 SLKK89 pKa = 10.01 AFFKK93 pKa = 7.7 MTPDD97 pKa = 3.08 NYY99 pKa = 10.24 KK100 pKa = 10.23 ISGTTIEE107 pKa = 4.34 FVEE110 pKa = 4.58 VTVTADD116 pKa = 2.72 VDD118 pKa = 3.34 KK119 pKa = 11.29 GIRR122 pKa = 11.84 EE123 pKa = 4.09 KK124 pKa = 10.8 KK125 pKa = 9.94 LKK127 pKa = 10.77 YY128 pKa = 9.61 EE129 pKa = 4.41 AGLTYY134 pKa = 9.88 IEE136 pKa = 4.31 QEE138 pKa = 3.87 LHH140 pKa = 6.57 KK141 pKa = 10.49 FFLKK145 pKa = 11.04 GEE147 pKa = 3.94 IPQPYY152 pKa = 9.54 KK153 pKa = 9.76 ITFNVVAVRR162 pKa = 11.84 TDD164 pKa = 3.04 GSNITTQWPSRR175 pKa = 11.84 RR176 pKa = 11.84 NDD178 pKa = 3.02 GVVQYY183 pKa = 9.77 MRR185 pKa = 11.84 LVQAEE190 pKa = 3.73 ISYY193 pKa = 10.19 VRR195 pKa = 11.84 EE196 pKa = 3.79 HH197 pKa = 7.15 LIKK200 pKa = 10.01 TEE202 pKa = 3.56 EE203 pKa = 4.04 RR204 pKa = 11.84 AALEE208 pKa = 4.02 AMFNLKK214 pKa = 10.49 FNISTHH220 pKa = 6.08 KK221 pKa = 9.86 SQPYY225 pKa = 9.1 YY226 pKa = 10.17 IPDD229 pKa = 3.6 YY230 pKa = 11.1 KK231 pKa = 11.22 GMEE234 pKa = 4.62 PIGANIEE241 pKa = 4.24 DD242 pKa = 3.96 LVDD245 pKa = 3.92 YY246 pKa = 11.22 SKK248 pKa = 11.47 DD249 pKa = 2.93 WLSRR253 pKa = 11.84 ARR255 pKa = 11.84 NFSFFEE261 pKa = 4.21 VKK263 pKa = 8.91 GTAVFEE269 pKa = 4.47 CFNSNEE275 pKa = 4.01 ANHH278 pKa = 5.8 CQRR281 pKa = 11.84 YY282 pKa = 8.08 PMSRR286 pKa = 11.84 KK287 pKa = 8.76 PRR289 pKa = 11.84 NFLLIQCSLITSYY302 pKa = 11.2 KK303 pKa = 9.75 PATTLSDD310 pKa = 3.52 QIDD313 pKa = 3.53 SRR315 pKa = 11.84 RR316 pKa = 11.84 ACSYY320 pKa = 10.36 ILNLIPDD327 pKa = 4.47 TPASYY332 pKa = 10.37 LIHH335 pKa = 7.34 DD336 pKa = 3.64 MAYY339 pKa = 10.32 RR340 pKa = 11.84 YY341 pKa = 10.08 INLTRR346 pKa = 11.84 EE347 pKa = 3.95 DD348 pKa = 4.22 MINYY352 pKa = 6.74 YY353 pKa = 10.59 APRR356 pKa = 11.84 IQFKK360 pKa = 8.08 QTQNVRR366 pKa = 11.84 EE367 pKa = 4.25 PGTFKK372 pKa = 10.31 LTSSMLRR379 pKa = 11.84 AEE381 pKa = 4.57 SKK383 pKa = 11.46 AMLDD387 pKa = 3.66 LLNNHH392 pKa = 6.85 KK393 pKa = 10.77 SGEE396 pKa = 4.03 KK397 pKa = 9.92 HH398 pKa = 5.11 GAQIEE403 pKa = 4.51 SLNIASHH410 pKa = 6.31 IVQSEE415 pKa = 4.5 SVSLITKK422 pKa = 9.82 ILSDD426 pKa = 4.06 LEE428 pKa = 4.54 LNITEE433 pKa = 5.18 PSTQEE438 pKa = 3.76 YY439 pKa = 8.07 STTKK443 pKa = 8.22 HH444 pKa = 5.68 TYY446 pKa = 10.05 VDD448 pKa = 3.55 TVLDD452 pKa = 3.66 KK453 pKa = 10.89 FFQNEE458 pKa = 4.12 TQKK461 pKa = 11.58 YY462 pKa = 9.75 LIDD465 pKa = 3.77 VLKK468 pKa = 9.71 KK469 pKa = 6.58 TTAWHH474 pKa = 6.1 IGHH477 pKa = 8.49 LIRR480 pKa = 11.84 DD481 pKa = 3.65 ITEE484 pKa = 3.77 SLIAHH489 pKa = 6.61 SGLKK493 pKa = 9.57 RR494 pKa = 11.84 SKK496 pKa = 8.49 YY497 pKa = 9.32 WSLHH501 pKa = 5.29 SYY503 pKa = 11.11 NNGNVILFILPSKK516 pKa = 9.94 SLEE519 pKa = 4.11 VAGSFIRR526 pKa = 11.84 FITVFRR532 pKa = 11.84 IGPGLVDD539 pKa = 4.93 KK540 pKa = 11.33 DD541 pKa = 3.9 NLDD544 pKa = 4.03 TILIDD549 pKa = 5.54 GDD551 pKa = 4.36 SQWGVSKK558 pKa = 11.17 VMSIDD563 pKa = 3.79 LNRR566 pKa = 11.84 LLALNIAFEE575 pKa = 4.29 KK576 pKa = 10.99 ALIATATWFQYY587 pKa = 8.65 YY588 pKa = 8.96 TEE590 pKa = 4.89 DD591 pKa = 3.27 QGQFPLQYY599 pKa = 10.48 AIRR602 pKa = 11.84 SVFANHH608 pKa = 6.57 FLLAICQKK616 pKa = 9.89 MKK618 pKa = 10.67 LCAIFDD624 pKa = 3.77 NLRR627 pKa = 11.84 YY628 pKa = 9.94 LIPAVTSLYY637 pKa = 10.89 SGFPSLIEE645 pKa = 3.95 KK646 pKa = 10.46 LFEE649 pKa = 4.32 RR650 pKa = 11.84 PFKK653 pKa = 10.97 SSLEE657 pKa = 3.84 VYY659 pKa = 9.74 IYY661 pKa = 11.14 YY662 pKa = 10.32 NIKK665 pKa = 10.27 SLLVALAQNNKK676 pKa = 9.25 ARR678 pKa = 11.84 FYY680 pKa = 11.44 SKK682 pKa = 11.01 VKK684 pKa = 10.66 LLGLTVDD691 pKa = 3.61 QSTVGASGVYY701 pKa = 9.17 PSFMSRR707 pKa = 11.84 IVYY710 pKa = 9.0 KK711 pKa = 10.2 HH712 pKa = 4.97 YY713 pKa = 10.44 RR714 pKa = 11.84 SLISEE719 pKa = 4.08 VTTCFFLFEE728 pKa = 4.93 KK729 pKa = 10.54 GLHH732 pKa = 5.82 GNMNEE737 pKa = 3.92 EE738 pKa = 4.11 AKK740 pKa = 10.28 IHH742 pKa = 6.37 LEE744 pKa = 4.09 TVEE747 pKa = 3.88 WALKK751 pKa = 10.02 FRR753 pKa = 11.84 EE754 pKa = 4.15 KK755 pKa = 10.57 EE756 pKa = 3.94 EE757 pKa = 4.4 KK758 pKa = 10.33 YY759 pKa = 10.99 GEE761 pKa = 4.22 SLVEE765 pKa = 3.82 NGYY768 pKa = 9.0 MMWEE772 pKa = 4.0 LRR774 pKa = 11.84 ANAEE778 pKa = 3.96 LAEE781 pKa = 4.02 QQLYY785 pKa = 9.59 CQDD788 pKa = 4.51 AIEE791 pKa = 4.33 LAAIEE796 pKa = 4.29 LNKK799 pKa = 10.05 VLATKK804 pKa = 10.59 SSVVANSILSKK815 pKa = 10.54 NWEE818 pKa = 4.13 EE819 pKa = 4.57 PYY821 pKa = 10.49 FSQTRR826 pKa = 11.84 NISLKK831 pKa = 10.41 GMSGQVQEE839 pKa = 5.26 DD840 pKa = 3.94 GHH842 pKa = 7.67 LSSSVTIIEE851 pKa = 4.86 AIRR854 pKa = 11.84 YY855 pKa = 7.89 LSNSRR860 pKa = 11.84 HH861 pKa = 5.45 NPSLLKK867 pKa = 10.55 LYY869 pKa = 10.81 EE870 pKa = 3.89 EE871 pKa = 4.35 TRR873 pKa = 11.84 EE874 pKa = 4.01 QKK876 pKa = 10.87 AMARR880 pKa = 11.84 IVRR883 pKa = 11.84 KK884 pKa = 7.56 YY885 pKa = 10.4 QRR887 pKa = 11.84 TEE889 pKa = 3.26 ADD891 pKa = 2.82 RR892 pKa = 11.84 GFFITTLPTRR902 pKa = 11.84 CRR904 pKa = 11.84 LEE906 pKa = 4.86 IIEE909 pKa = 5.2 DD910 pKa = 4.13 YY911 pKa = 11.28 YY912 pKa = 11.65 DD913 pKa = 5.51 AIAKK917 pKa = 9.57 NISEE921 pKa = 4.61 EE922 pKa = 4.25 YY923 pKa = 9.9 ISYY926 pKa = 10.67 GGEE929 pKa = 3.95 KK930 pKa = 9.97 KK931 pKa = 10.25 ILAIQGALEE940 pKa = 4.05 KK941 pKa = 10.58 ALRR944 pKa = 11.84 WASGEE949 pKa = 4.18 SFIEE953 pKa = 4.03 LSNHH957 pKa = 5.04 KK958 pKa = 9.82 FIRR961 pKa = 11.84 MKK963 pKa = 10.47 RR964 pKa = 11.84 KK965 pKa = 9.85 LMYY968 pKa = 10.45 VSADD972 pKa = 3.22 ATKK975 pKa = 9.98 WSPGDD980 pKa = 3.31 NSAKK984 pKa = 9.7 FRR986 pKa = 11.84 RR987 pKa = 11.84 FTSMLHH993 pKa = 6.44 NGLPNNKK1000 pKa = 9.38 LKK1002 pKa = 11.14 NCVIDD1007 pKa = 4.3 ALKK1010 pKa = 10.29 QVYY1013 pKa = 7.98 KK1014 pKa = 10.5 TDD1016 pKa = 3.68 FFMSRR1021 pKa = 11.84 KK1022 pKa = 8.29 LRR1024 pKa = 11.84 NYY1026 pKa = 8.26 IDD1028 pKa = 3.59 SMEE1031 pKa = 4.42 SLDD1034 pKa = 3.65 PHH1036 pKa = 6.9 IKK1038 pKa = 10.12 QFLDD1042 pKa = 4.07 FFPDD1046 pKa = 3.3 GHH1048 pKa = 7.68 HH1049 pKa = 7.06 GEE1051 pKa = 4.57 VKK1053 pKa = 10.85 GNWLQGNLNKK1063 pKa = 10.24 CSSLFGVAMSLLFKK1077 pKa = 10.27 QVWTNLFPEE1086 pKa = 4.82 LDD1088 pKa = 3.82 CFFEE1092 pKa = 4.59 FAHH1095 pKa = 6.73 HH1096 pKa = 6.98 SDD1098 pKa = 3.78 DD1099 pKa = 3.8 ALFIYY1104 pKa = 9.85 GYY1106 pKa = 10.29 LEE1108 pKa = 4.32 PVDD1111 pKa = 6.0 DD1112 pKa = 4.32 GTDD1115 pKa = 2.66 WFLFVSQQIQAGHH1128 pKa = 5.66 LHH1130 pKa = 6.18 WFSVNTEE1137 pKa = 3.46 MWKK1140 pKa = 10.93 SMFNLHH1146 pKa = 5.5 EE1147 pKa = 5.42 HH1148 pKa = 6.37 ILLLGSIKK1156 pKa = 10.17 ISPKK1160 pKa = 8.91 KK1161 pKa = 7.32 TTVSPTNAEE1170 pKa = 3.94 FLSTFFEE1177 pKa = 4.95 GCAVSIPFVKK1187 pKa = 10.18 ILLGSLSDD1195 pKa = 4.29 LPGLGYY1201 pKa = 10.41 FDD1203 pKa = 5.73 DD1204 pKa = 4.57 LAAAQSRR1211 pKa = 11.84 CVKK1214 pKa = 10.58 ALDD1217 pKa = 4.55 LGASPQVAQLAVALCTSKK1235 pKa = 10.93 VEE1237 pKa = 4.21 RR1238 pKa = 11.84 LYY1240 pKa = 10.3 GTAPGMVNHH1249 pKa = 7.15 PAAYY1253 pKa = 9.72 LQVKK1257 pKa = 8.1 HH1258 pKa = 6.62 TDD1260 pKa = 3.11 TPIPLGGNGAMSIMEE1275 pKa = 4.97 LATAGIGMSDD1285 pKa = 3.26 KK1286 pKa = 11.13 NLLKK1290 pKa = 10.47 RR1291 pKa = 11.84 ALLGYY1296 pKa = 7.24 SHH1298 pKa = 7.19 KK1299 pKa = 10.13 RR1300 pKa = 11.84 QKK1302 pKa = 11.31 SMLYY1306 pKa = 9.84 ILGLFKK1312 pKa = 10.83 FLMKK1316 pKa = 10.83 LSDD1319 pKa = 3.16 EE1320 pKa = 4.57 TFQHH1324 pKa = 5.74 EE1325 pKa = 4.32 RR1326 pKa = 11.84 LGQFSFIGKK1335 pKa = 6.9 VQWKK1339 pKa = 9.55 IFTPKK1344 pKa = 10.37 SEE1346 pKa = 4.34 FEE1348 pKa = 4.04 FADD1351 pKa = 3.67 MYY1353 pKa = 10.26 TSKK1356 pKa = 10.59 FLEE1359 pKa = 4.51 LWSSQHH1365 pKa = 4.32 VTYY1368 pKa = 10.52 DD1369 pKa = 3.26 YY1370 pKa = 10.53 IIPKK1374 pKa = 10.24 GRR1376 pKa = 11.84 DD1377 pKa = 2.99 NLLIYY1382 pKa = 10.13 LVRR1385 pKa = 11.84 KK1386 pKa = 10.09 LNDD1389 pKa = 3.67 PSIVTAMTMQSPLQLRR1405 pKa = 11.84 FRR1407 pKa = 11.84 MQAKK1411 pKa = 8.76 QHH1413 pKa = 5.53 MKK1415 pKa = 9.57 VCRR1418 pKa = 11.84 LDD1420 pKa = 4.19 GEE1422 pKa = 4.52 WVTFRR1427 pKa = 11.84 EE1428 pKa = 4.22 VLAAANSFAEE1438 pKa = 4.48 NYY1440 pKa = 9.73 SATSQDD1446 pKa = 2.53 MDD1448 pKa = 4.25 LFQTLTSCTFSKK1460 pKa = 10.52 EE1461 pKa = 4.09 YY1462 pKa = 10.24 AWKK1465 pKa = 10.51 DD1466 pKa = 3.45 FLNGIHH1472 pKa = 7.14 CDD1474 pKa = 3.81 VIPTKK1479 pKa = 10.13 QVQRR1483 pKa = 11.84 AKK1485 pKa = 10.05 VARR1488 pKa = 11.84 TFTVRR1493 pKa = 11.84 EE1494 pKa = 3.88 KK1495 pKa = 11.21 DD1496 pKa = 3.43 QIIQNSIPAVIGYY1509 pKa = 9.08 KK1510 pKa = 10.11 FAVTVEE1516 pKa = 4.08 EE1517 pKa = 4.3 MSDD1520 pKa = 3.48 VLDD1523 pKa = 3.63 TAKK1526 pKa = 10.65 FPDD1529 pKa = 4.16 SLSVDD1534 pKa = 4.21 LKK1536 pKa = 9.19 TMKK1539 pKa = 10.63 DD1540 pKa = 3.23 GVYY1543 pKa = 10.04 RR1544 pKa = 11.84 EE1545 pKa = 4.51 LGLDD1549 pKa = 3.05 ISLPDD1554 pKa = 3.36 VMKK1557 pKa = 10.82 RR1558 pKa = 11.84 IAPMLYY1564 pKa = 9.17 KK1565 pKa = 10.23 SSKK1568 pKa = 8.05 SRR1570 pKa = 11.84 VVIVQGNVEE1579 pKa = 4.13 GTAEE1583 pKa = 4.64 AICRR1587 pKa = 11.84 YY1588 pKa = 7.04 WLKK1591 pKa = 11.27 SMSLVKK1597 pKa = 9.78 TIRR1600 pKa = 11.84 VKK1602 pKa = 9.68 PHH1604 pKa = 6.57 KK1605 pKa = 9.88 EE1606 pKa = 3.45 VLQAVSIFNRR1616 pKa = 11.84 KK1617 pKa = 7.93 EE1618 pKa = 4.28 DD1619 pKa = 3.16 IGQQKK1624 pKa = 10.37 DD1625 pKa = 3.17 LAALKK1630 pKa = 10.62 LCIEE1634 pKa = 4.11 VWRR1637 pKa = 11.84 WCKK1640 pKa = 10.77 ANSAPYY1646 pKa = 9.96 RR1647 pKa = 11.84 DD1648 pKa = 3.65 WFQALWFEE1656 pKa = 5.06 DD1657 pKa = 3.4 KK1658 pKa = 10.81 TFSEE1662 pKa = 4.22 WLDD1665 pKa = 3.35 RR1666 pKa = 11.84 FCRR1669 pKa = 11.84 VGVPPIDD1676 pKa = 5.05 PEE1678 pKa = 4.22 IQCAALMIADD1688 pKa = 3.8 IKK1690 pKa = 11.15 GDD1692 pKa = 3.68 YY1693 pKa = 10.56 SVLQLQANRR1702 pKa = 11.84 RR1703 pKa = 11.84 AYY1705 pKa = 10.45 SGKK1708 pKa = 10.2 QYY1710 pKa = 11.06 DD1711 pKa = 4.14 AYY1713 pKa = 10.92 CVQTYY1718 pKa = 11.07 NEE1720 pKa = 4.09 VTKK1723 pKa = 10.65 LYY1725 pKa = 10.64 EE1726 pKa = 4.4 GDD1728 pKa = 3.59 LRR1730 pKa = 11.84 VTFNFGLDD1738 pKa = 3.54 CARR1741 pKa = 11.84 LEE1743 pKa = 4.27 IFWDD1747 pKa = 3.34 KK1748 pKa = 10.73 KK1749 pKa = 11.04 AYY1751 pKa = 9.56 ILEE1754 pKa = 4.09 TSITQKK1760 pKa = 10.62 HH1761 pKa = 5.13 VLKK1764 pKa = 10.89 IMMDD1768 pKa = 3.68 EE1769 pKa = 4.17 VSKK1772 pKa = 10.92 EE1773 pKa = 3.94 LIKK1776 pKa = 10.98 CGMRR1780 pKa = 11.84 FNTEE1784 pKa = 3.34 QVQGVRR1790 pKa = 11.84 HH1791 pKa = 5.07 MVLFKK1796 pKa = 10.71 TEE1798 pKa = 4.78 SGFEE1802 pKa = 3.75 WGKK1805 pKa = 10.08 PNIPCIVYY1813 pKa = 9.82 KK1814 pKa = 10.86 NCVLRR1819 pKa = 11.84 TSLRR1823 pKa = 11.84 TTQAINHH1830 pKa = 6.46 KK1831 pKa = 10.51 FMITIKK1837 pKa = 10.7 DD1838 pKa = 3.46 DD1839 pKa = 3.55 GLRR1842 pKa = 11.84 AIAQHH1847 pKa = 7.03 DD1848 pKa = 3.81 EE1849 pKa = 4.0 DD1850 pKa = 4.32 SPRR1853 pKa = 11.84 FLLAHH1858 pKa = 7.1 AFHH1861 pKa = 7.64 TIRR1864 pKa = 11.84 DD1865 pKa = 3.37 IRR1867 pKa = 11.84 YY1868 pKa = 7.63 QAVDD1872 pKa = 3.11 AVSNVWFIHH1881 pKa = 6.02 KK1882 pKa = 9.84 GVKK1885 pKa = 10.09 LYY1887 pKa = 10.75 LNPIISSGLLEE1898 pKa = 4.71 NFMKK1902 pKa = 10.52 NLPAAIPPAAYY1913 pKa = 10.39 SLIMNRR1919 pKa = 11.84 AKK1921 pKa = 10.51 ISVDD1925 pKa = 2.8 LFMFNDD1931 pKa = 3.98 LLKK1934 pKa = 10.95 LINPRR1939 pKa = 11.84 NTLDD1943 pKa = 3.72 LSGLEE1948 pKa = 4.12 TTGDD1952 pKa = 3.59 EE1953 pKa = 4.47 FSTVSSMSSRR1963 pKa = 11.84 LWSEE1967 pKa = 3.82 EE1968 pKa = 3.52 MSLVDD1973 pKa = 6.06 DD1974 pKa = 5.81 DD1975 pKa = 5.74 EE1976 pKa = 4.84 EE1977 pKa = 6.37 LDD1979 pKa = 4.68 DD1980 pKa = 5.51 EE1981 pKa = 4.7 FTIDD1985 pKa = 3.69 LQDD1988 pKa = 3.14 VDD1990 pKa = 5.4 FEE1992 pKa = 5.15 NIDD1995 pKa = 3.33 IEE1997 pKa = 4.49 ADD1999 pKa = 3.23 IEE2001 pKa = 4.72 HH2002 pKa = 7.03 FLQDD2006 pKa = 3.38 EE2007 pKa = 4.25 SSYY2010 pKa = 11.22 TGDD2013 pKa = 3.77 LLISTEE2019 pKa = 4.03 EE2020 pKa = 4.29 TEE2022 pKa = 4.42 SKK2024 pKa = 10.56 KK2025 pKa = 10.0 MRR2027 pKa = 11.84 GIVKK2031 pKa = 9.38 ILEE2034 pKa = 4.11 PVRR2037 pKa = 11.84 LIKK2040 pKa = 10.58 SWVSRR2045 pKa = 11.84 GLSIEE2050 pKa = 4.22 KK2051 pKa = 10.23 VYY2053 pKa = 11.34 SPVNIILMSRR2063 pKa = 11.84 YY2064 pKa = 9.17 ISKK2067 pKa = 8.81 TFNLSTKK2074 pKa = 9.47 QVSLLDD2080 pKa = 4.49 PYY2082 pKa = 11.58 DD2083 pKa = 3.72 LTEE2086 pKa = 4.47 LEE2088 pKa = 4.57 SIVRR2092 pKa = 11.84 GWGEE2096 pKa = 3.81 CVIDD2100 pKa = 3.86 QFEE2103 pKa = 4.37 SLDD2106 pKa = 3.68 RR2107 pKa = 11.84 EE2108 pKa = 4.48 AQNMVVNKK2116 pKa = 8.58 GICPEE2121 pKa = 4.0 DD2122 pKa = 4.04 VIPDD2126 pKa = 3.55 SLFSFRR2132 pKa = 11.84 HH2133 pKa = 4.42 TMVLLRR2139 pKa = 11.84 RR2140 pKa = 11.84 LFPQDD2145 pKa = 4.03 SISSFYY2151 pKa = 11.41
Molecular weight: 246.5 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 6.332
IPC2_protein 6.389
IPC_protein 6.44
Toseland 6.634
ProMoST 6.898
Dawson 6.825
Bjellqvist 6.854
Wikipedia 6.839
Rodwell 6.825
Grimsley 6.766
Solomon 6.825
Lehninger 6.825
Nozaki 7.132
DTASelect 7.249
Thurlkill 7.278
EMBOSS 7.249
Sillero 7.234
Patrickios 4.253
IPC_peptide 6.839
IPC2_peptide 6.883
IPC2.peptide.svr19 6.847
Peptides (in silico digests for buttom-up proteomics)
Below you can find
in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.
Try ESI
ChTry ESI
ArgC ESI
LysN ESI
TryLysC ESI
Try MALDI
ChTry MALDI
ArgC MALDI
LysN MALDI
TryLysC MALDI
Try LTQ
ChTry LTQ
ArgC LTQ
LysN LTQ
TryLysC LTQ
Try MSlow
ChTry MSlow
ArgC MSlow
LysN MSlow
TryLysC MSlow
Try MShigh
ChTry MShigh
ArgC MShigh
LysN MShigh
TryLysC MShigh
General Statistics
Number of major isoforms
Number of additional isoforms
Number of all proteins
Number of amino acids
Min. Seq. Length
Max. Seq. Length
Avg. Seq. Length
Avg. Mol. Weight
3
0
3
3715
429
2151
1238.3
140.35
Amino acid frequency
Ala
Cys
Asp
Glu
Phe
Gly
His
Ile
Lys
Leu
5.895 ± 0.648
2.611 ± 1.214
5.384 ± 0.449
6.057 ± 0.425
4.899 ± 0.535
5.464 ± 0.787
2.503 ± 0.338
7.026 ± 0.155
6.703 ± 0.365
9.421 ± 0.818
Met
Asn
Gln
Pro
Arg
Ser
Thr
Val
Trp
Tyr
2.584 ± 0.258
3.957 ± 0.31
3.822 ± 0.38
3.769 ± 0.433
4.361 ± 0.68
7.995 ± 0.382
5.868 ± 0.528
6.406 ± 0.594
1.534 ± 0.092
3.742 ± 0.33
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level
Most of the basic statistics you can see at this page can be downloaded from this CSV file
For dipeptide frequency statistics click here