Human papillomavirus type 203
Average proteome isoelectric point is 6.34
Get precalculated fractions of proteins
Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
All
Note: above files contain also dissociation constants (pKa)
Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)
Get csv file with sequences according to given criteria:
* You can choose from 21 different methods for calculating isoelectric point
Summary statistics related to proteome-wise predictions
Protein with the lowest isoelectric point:
>tr|A0A2L1K401|A0A2L1K401_9PAPI Regulatory protein E2 OS=Human papillomavirus type 203 OX=2093789 GN=E2 PE=3 SV=1
MM1 pKa = 7.42 SLTRR5 pKa = 11.84 ARR7 pKa = 11.84 RR8 pKa = 11.84 VKK10 pKa = 10.33 RR11 pKa = 11.84 DD12 pKa = 3.33 SVQNLYY18 pKa = 9.71 NQCQLTGNCLPDD30 pKa = 3.28 VKK32 pKa = 10.99 NKK34 pKa = 10.04 VEE36 pKa = 4.14 GTTLADD42 pKa = 3.35 KK43 pKa = 10.52 LLKK46 pKa = 10.12 IFSSIIYY53 pKa = 10.23 LGGLSIGTGKK63 pKa = 8.72 GTGGSTGYY71 pKa = 8.83 TPLGGTTGGGRR82 pKa = 11.84 VGTGGTVVRR91 pKa = 11.84 PNVVVEE97 pKa = 4.04 PLGPTDD103 pKa = 3.78 IVPVDD108 pKa = 3.64 TLNPNSSSIVPLLEE122 pKa = 4.59 AGPDD126 pKa = 3.6 IIISEE131 pKa = 4.47 SAPGPKK137 pKa = 9.84 VNLPDD142 pKa = 4.43 AGTDD146 pKa = 3.52 LGISEE151 pKa = 5.24 LDD153 pKa = 3.04 IVTTSDD159 pKa = 3.29 PVSDD163 pKa = 3.75 VTIGNAGGPTVSTSEE178 pKa = 4.24 DD179 pKa = 3.22 SVAIIDD185 pKa = 3.94 VQPASSTPRR194 pKa = 11.84 RR195 pKa = 11.84 VATSTYY201 pKa = 10.16 NNPSYY206 pKa = 9.93 VTVYY210 pKa = 10.4 SQSTLAEE217 pKa = 3.98 EE218 pKa = 4.25 TSANINVFVDD228 pKa = 3.51 SAFGGDD234 pKa = 3.78 VIGSSGQDD242 pKa = 2.81 IPLEE246 pKa = 4.19 TFNVSSDD253 pKa = 3.29 LAEE256 pKa = 4.34 FEE258 pKa = 4.45 IEE260 pKa = 4.14 EE261 pKa = 4.52 PPRR264 pKa = 11.84 TSTPRR269 pKa = 11.84 DD270 pKa = 3.42 TIEE273 pKa = 4.5 RR274 pKa = 11.84 ALQRR278 pKa = 11.84 ARR280 pKa = 11.84 DD281 pKa = 3.89 LYY283 pKa = 9.81 QRR285 pKa = 11.84 RR286 pKa = 11.84 VQQVRR291 pKa = 11.84 TRR293 pKa = 11.84 NVDD296 pKa = 3.73 FLGRR300 pKa = 11.84 PQMAVQFQFEE310 pKa = 4.32 NPAFEE315 pKa = 5.95 DD316 pKa = 4.96 DD317 pKa = 3.2 ITLTFEE323 pKa = 4.07 QDD325 pKa = 3.24 LNQLATAAPDD335 pKa = 3.56 ADD337 pKa = 3.77 FADD340 pKa = 4.92 VIRR343 pKa = 11.84 LHH345 pKa = 6.5 RR346 pKa = 11.84 PRR348 pKa = 11.84 YY349 pKa = 8.97 SVTDD353 pKa = 3.44 AGTVRR358 pKa = 11.84 VSRR361 pKa = 11.84 LGQRR365 pKa = 11.84 GTIHH369 pKa = 6.15 TRR371 pKa = 11.84 SGLQIGQQVHH381 pKa = 6.5 FYY383 pKa = 11.02 YY384 pKa = 10.49 DD385 pKa = 2.97 ISDD388 pKa = 3.89 IEE390 pKa = 3.97 PAEE393 pKa = 4.48 AIEE396 pKa = 3.96 LTLLGEE402 pKa = 4.58 HH403 pKa = 6.48 SGEE406 pKa = 3.88 AAVVNAQSEE415 pKa = 4.91 STVVDD420 pKa = 3.79 AEE422 pKa = 4.35 NSNSPFLYY430 pKa = 10.1 PEE432 pKa = 4.42 EE433 pKa = 4.13 EE434 pKa = 4.97 LIDD437 pKa = 3.88 VPTEE441 pKa = 4.1 DD442 pKa = 4.98 FSDD445 pKa = 3.46 SHH447 pKa = 7.57 LVLSSNSRR455 pKa = 11.84 RR456 pKa = 11.84 SYY458 pKa = 9.21 ITTPTLPPGTALRR471 pKa = 11.84 VFIDD475 pKa = 4.49 DD476 pKa = 3.73 YY477 pKa = 11.94 ANGLFVSYY485 pKa = 10.42 PEE487 pKa = 4.78 TYY489 pKa = 10.31 NPPQIIVPAEE499 pKa = 3.9 NLPPTVLIDD508 pKa = 3.67 SFNSNDD514 pKa = 3.97 FILHH518 pKa = 6.23 PSHH521 pKa = 6.74 NKK523 pKa = 8.03 RR524 pKa = 11.84 RR525 pKa = 11.84 KK526 pKa = 9.04 RR527 pKa = 11.84 KK528 pKa = 9.99 RR529 pKa = 11.84 GDD531 pKa = 3.05 VV532 pKa = 3.33
Molecular weight: 57.41 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 4.632
IPC2_protein 4.571
IPC_protein 4.546
Toseland 4.38
ProMoST 4.66
Dawson 4.507
Bjellqvist 4.647
Wikipedia 4.393
Rodwell 4.38
Grimsley 4.279
Solomon 4.495
Lehninger 4.457
Nozaki 4.609
DTASelect 4.813
Thurlkill 4.38
EMBOSS 4.406
Sillero 4.66
Patrickios 3.986
IPC_peptide 4.507
IPC2_peptide 4.647
IPC2.peptide.svr19 4.636
Protein with the highest isoelectric point:
>tr|A0A2L1K403|A0A2L1K403_9PAPI Major capsid protein L1 OS=Human papillomavirus type 203 OX=2093789 GN=L1 PE=3 SV=1
MM1 pKa = 7.47 EE2 pKa = 4.9 SLRR5 pKa = 11.84 EE6 pKa = 3.93 RR7 pKa = 11.84 FDD9 pKa = 3.65 ALQEE13 pKa = 3.98 KK14 pKa = 10.4 LIEE17 pKa = 4.36 IYY19 pKa = 10.4 EE20 pKa = 4.38 AGSTNLEE27 pKa = 4.07 DD28 pKa = 5.48 QIKK31 pKa = 9.79 HH32 pKa = 4.58 WDD34 pKa = 3.28 IVRR37 pKa = 11.84 KK38 pKa = 9.69 EE39 pKa = 3.95 SVIMHH44 pKa = 6.28 FARR47 pKa = 11.84 RR48 pKa = 11.84 KK49 pKa = 8.8 GLTRR53 pKa = 11.84 LGLQQLPALTVSEE66 pKa = 4.63 TNAKK70 pKa = 8.7 NAIMMSIYY78 pKa = 10.31 LQSLNNSQYY87 pKa = 11.49 ASEE90 pKa = 4.18 SWGLSDD96 pKa = 4.41 TSLEE100 pKa = 4.32 LFLTAPMHH108 pKa = 5.26 TFKK111 pKa = 11.05 KK112 pKa = 9.76 SGYY115 pKa = 8.92 SVDD118 pKa = 3.62 VLFDD122 pKa = 3.73 NDD124 pKa = 3.36 EE125 pKa = 4.77 DD126 pKa = 3.96 NLYY129 pKa = 10.19 TYY131 pKa = 7.36 TAWRR135 pKa = 11.84 FVYY138 pKa = 10.55 YY139 pKa = 10.28 QDD141 pKa = 6.3 DD142 pKa = 3.56 EE143 pKa = 5.28 GEE145 pKa = 4.04 WHH147 pKa = 6.29 KK148 pKa = 11.39 VEE150 pKa = 5.48 SGVDD154 pKa = 3.41 YY155 pKa = 11.37 DD156 pKa = 4.33 GIFYY160 pKa = 8.73 KK161 pKa = 10.38 TVEE164 pKa = 4.22 NHH166 pKa = 4.14 TEE168 pKa = 3.84 YY169 pKa = 11.11 YY170 pKa = 10.11 IRR172 pKa = 11.84 FQDD175 pKa = 3.66 DD176 pKa = 3.25 APRR179 pKa = 11.84 FSRR182 pKa = 11.84 TGRR185 pKa = 11.84 WTVKK189 pKa = 10.44 YY190 pKa = 9.94 KK191 pKa = 10.76 SQTISTSVTSTSGSDD206 pKa = 3.26 PVSSSEE212 pKa = 4.9 RR213 pKa = 11.84 PTQQSSDD220 pKa = 3.7 TLDD223 pKa = 4.39 APPQPKK229 pKa = 9.7 KK230 pKa = 10.71 FRR232 pKa = 11.84 VRR234 pKa = 11.84 PPQQTGPSRR243 pKa = 11.84 VSSSSNSKK251 pKa = 5.43 TTKK254 pKa = 10.17 KK255 pKa = 10.25 EE256 pKa = 4.05 SPKK259 pKa = 9.01 TRR261 pKa = 11.84 LRR263 pKa = 11.84 RR264 pKa = 11.84 RR265 pKa = 11.84 RR266 pKa = 11.84 GEE268 pKa = 4.09 GEE270 pKa = 3.66 PTTRR274 pKa = 11.84 ATNRR278 pKa = 11.84 RR279 pKa = 11.84 TTSGRR284 pKa = 11.84 ARR286 pKa = 11.84 RR287 pKa = 11.84 RR288 pKa = 11.84 LEE290 pKa = 3.66 YY291 pKa = 10.16 AYY293 pKa = 7.06 PTPEE297 pKa = 3.77 QVGSVHH303 pKa = 7.48 RR304 pKa = 11.84 LPQGSNLGRR313 pKa = 11.84 LGRR316 pKa = 11.84 LQEE319 pKa = 4.12 EE320 pKa = 4.38 ARR322 pKa = 11.84 DD323 pKa = 3.85 PPVVLLRR330 pKa = 11.84 GLANTLKK337 pKa = 10.55 CFRR340 pKa = 11.84 FRR342 pKa = 11.84 CKK344 pKa = 10.02 QKK346 pKa = 10.74 YY347 pKa = 9.45 KK348 pKa = 11.17 GLFQHH353 pKa = 7.24 ISTTFSWVGEE363 pKa = 4.27 GYY365 pKa = 10.31 EE366 pKa = 3.93 RR367 pKa = 11.84 LGNARR372 pKa = 11.84 ILIAFQSTAQRR383 pKa = 11.84 EE384 pKa = 4.25 KK385 pKa = 10.03 FLAVAVLPKK394 pKa = 9.71 GTEE397 pKa = 3.89 VVYY400 pKa = 10.99 GSLNALL406 pKa = 3.72
Molecular weight: 46.42 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 8.873
IPC2_protein 9.033
IPC_protein 9.033
Toseland 9.56
ProMoST 9.385
Dawson 9.853
Bjellqvist 9.575
Wikipedia 10.058
Rodwell 10.058
Grimsley 9.955
Solomon 9.882
Lehninger 9.838
Nozaki 9.575
DTASelect 9.56
Thurlkill 9.677
EMBOSS 9.999
Sillero 9.78
Patrickios 5.029
IPC_peptide 9.882
IPC2_peptide 8.17
IPC2.peptide.svr19 7.963
Peptides (in silico digests for buttom-up proteomics)
Below you can find
in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.
Try ESI
ChTry ESI
ArgC ESI
LysN ESI
TryLysC ESI
Try MALDI
ChTry MALDI
ArgC MALDI
LysN MALDI
TryLysC MALDI
Try LTQ
ChTry LTQ
ArgC LTQ
LysN LTQ
TryLysC LTQ
Try MSlow
ChTry MSlow
ArgC MSlow
LysN MSlow
TryLysC MSlow
Try MShigh
ChTry MShigh
ArgC MShigh
LysN MShigh
TryLysC MShigh
General Statistics
Number of major isoforms
Number of additional isoforms
Number of all proteins
Number of amino acids
Min. Seq. Length
Max. Seq. Length
Avg. Seq. Length
Avg. Mol. Weight
7
0
7
2370
70
613
338.6
38.16
Amino acid frequency
Ala
Cys
Asp
Glu
Phe
Gly
His
Ile
Lys
Leu
5.485 ± 0.185
2.236 ± 1.004
6.371 ± 0.406
6.287 ± 0.64
4.388 ± 0.418
5.654 ± 0.644
1.772 ± 0.274
4.895 ± 0.653
5.021 ± 0.99
9.536 ± 0.79
Met
Asn
Gln
Pro
Arg
Ser
Thr
Val
Trp
Tyr
1.857 ± 0.574
5.232 ± 0.683
5.485 ± 0.85
4.051 ± 0.344
5.907 ± 0.903
7.764 ± 0.693
6.54 ± 0.812
6.962 ± 0.596
1.181 ± 0.339
3.376 ± 0.307
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level
Most of the basic statistics you can see at this page can be downloaded from this CSV file
For dipeptide frequency statistics click here