Amino acid dipepetide frequency for Guanarito mammarenavirus (isolate Human/Venezuela/NH-95551/1990) (GTOV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.501AlaAla: 1.501 ± 1.085
1.201AlaCys: 1.201 ± 0.345
1.801AlaAsp: 1.801 ± 1.132
2.702AlaGlu: 2.702 ± 0.836
1.801AlaPhe: 1.801 ± 0.203
2.702AlaGly: 2.702 ± 1.456
2.101AlaHis: 2.101 ± 0.636
2.101AlaIle: 2.101 ± 1.667
1.801AlaLys: 1.801 ± 0.582
5.704AlaLeu: 5.704 ± 1.142
0.6AlaMet: 0.6 ± 0.335
1.501AlaAsn: 1.501 ± 0.455
2.101AlaPro: 2.101 ± 2.131
0.901AlaGln: 0.901 ± 0.303
0.901AlaArg: 0.901 ± 0.303
1.801AlaSer: 1.801 ± 0.606
0.901AlaThr: 0.901 ± 0.484
4.503AlaVal: 4.503 ± 0.614
0.0AlaTrp: 0.0 ± 0.0
1.201AlaTyr: 1.201 ± 0.645
0.0AlaXaa: 0.0 ± 0.0
Cys
1.801CysAla: 1.801 ± 0.586
1.501CysCys: 1.501 ± 1.107
0.901CysAsp: 0.901 ± 0.324
2.402CysGlu: 2.402 ± 0.891
2.101CysPhe: 2.101 ± 0.512
0.6CysGly: 0.6 ± 0.351
0.3CysHis: 0.3 ± 0.161
1.501CysIle: 1.501 ± 1.146
1.501CysLys: 1.501 ± 1.113
3.002CysLeu: 3.002 ± 2.101
0.3CysMet: 0.3 ± 0.43
1.801CysAsn: 1.801 ± 1.282
1.201CysPro: 1.201 ± 0.372
0.3CysGln: 0.3 ± 0.161
1.501CysArg: 1.501 ± 0.73
3.002CysSer: 3.002 ± 1.367
0.6CysThr: 0.6 ± 0.323
1.801CysVal: 1.801 ± 0.968
0.901CysTrp: 0.901 ± 2.439
1.201CysTyr: 1.201 ± 0.645
0.0CysXaa: 0.0 ± 0.0
Asp
1.801AspAla: 1.801 ± 0.606
1.501AspCys: 1.501 ± 0.618
2.101AspAsp: 2.101 ± 0.636
3.002AspGlu: 3.002 ± 1.237
4.803AspPhe: 4.803 ± 1.048
4.203AspGly: 4.203 ± 1.457
0.901AspHis: 0.901 ± 1.219
3.002AspIle: 3.002 ± 0.722
1.501AspLys: 1.501 ± 1.026
8.406AspLeu: 8.406 ± 2.178
2.702AspMet: 2.702 ± 0.836
1.201AspAsn: 1.201 ± 0.864
3.002AspPro: 3.002 ± 0.926
1.801AspGln: 1.801 ± 0.968
3.002AspArg: 3.002 ± 0.465
3.302AspSer: 3.302 ± 0.811
1.801AspThr: 1.801 ± 1.006
4.203AspVal: 4.203 ± 0.952
1.201AspTrp: 1.201 ± 0.372
0.6AspTyr: 0.6 ± 0.323
0.0AspXaa: 0.0 ± 0.0
Glu
2.702GluAla: 2.702 ± 0.792
2.702GluCys: 2.702 ± 1.452
4.503GluAsp: 4.503 ± 1.977
5.104GluGlu: 5.104 ± 2.008
4.803GluPhe: 4.803 ± 1.454
3.002GluGly: 3.002 ± 0.722
2.402GluHis: 2.402 ± 0.415
4.503GluIle: 4.503 ± 1.506
6.605GluLys: 6.605 ± 1.596
6.304GluLeu: 6.304 ± 1.671
2.702GluMet: 2.702 ± 0.643
1.501GluAsn: 1.501 ± 0.455
2.702GluPro: 2.702 ± 0.958
3.903GluGln: 3.903 ± 1.141
2.402GluArg: 2.402 ± 0.415
5.104GluSer: 5.104 ± 0.781
3.302GluThr: 3.302 ± 0.551
3.603GluVal: 3.603 ± 0.673
0.901GluTrp: 0.901 ± 0.324
2.101GluTyr: 2.101 ± 0.678
0.0GluXaa: 0.0 ± 0.0
Phe
0.3PheAla: 0.3 ± 1.173
0.901PheCys: 0.901 ± 0.324
3.002PheAsp: 3.002 ± 0.497
3.903PheGlu: 3.903 ± 0.837
4.503PhePhe: 4.503 ± 1.415
2.402PheGly: 2.402 ± 0.689
1.201PheHis: 1.201 ± 0.372
1.801PheIle: 1.801 ± 0.586
3.302PheLys: 3.302 ± 0.871
5.104PheLeu: 5.104 ± 1.575
1.201PheMet: 1.201 ± 0.645
2.101PheAsn: 2.101 ± 0.743
0.3PhePro: 0.3 ± 0.44
2.402PheGln: 2.402 ± 2.087
1.801PheArg: 1.801 ± 1.29
3.603PheSer: 3.603 ± 0.673
3.903PheThr: 3.903 ± 0.643
4.503PheVal: 4.503 ± 1.506
1.201PheTrp: 1.201 ± 0.701
1.201PheTyr: 1.201 ± 0.645
0.0PheXaa: 0.0 ± 0.0
Gly
2.702GlyAla: 2.702 ± 1.28
0.3GlyCys: 0.3 ± 0.161
3.603GlyAsp: 3.603 ± 0.672
4.803GlyGlu: 4.803 ± 0.99
3.603GlyPhe: 3.603 ± 0.673
2.101GlyGly: 2.101 ± 1.312
2.101GlyHis: 2.101 ± 0.826
3.302GlyIle: 3.302 ± 0.811
2.101GlyLys: 2.101 ± 0.512
5.104GlyLeu: 5.104 ± 1.113
0.901GlyMet: 0.901 ± 0.754
3.603GlyAsn: 3.603 ± 1.942
1.501GlyPro: 1.501 ± 0.618
1.501GlyGln: 1.501 ± 0.73
2.702GlyArg: 2.702 ± 1.64
5.404GlySer: 5.404 ± 0.804
1.801GlyThr: 1.801 ± 0.968
3.302GlyVal: 3.302 ± 0.551
0.6GlyTrp: 0.6 ± 0.636
2.101GlyTyr: 2.101 ± 0.512
0.0GlyXaa: 0.0 ± 0.0
His
0.3HisAla: 0.3 ± 0.161
0.6HisCys: 0.6 ± 0.86
1.501HisAsp: 1.501 ± 1.12
0.6HisGlu: 0.6 ± 0.351
0.0HisPhe: 0.0 ± 0.0
0.901HisGly: 0.901 ± 0.754
0.901HisHis: 0.901 ± 0.779
2.101HisIle: 2.101 ± 0.743
1.501HisLys: 1.501 ± 0.807
4.203HisLeu: 4.203 ± 0.608
0.6HisMet: 0.6 ± 0.298
1.201HisAsn: 1.201 ± 0.345
0.3HisPro: 0.3 ± 0.44
0.6HisGln: 0.6 ± 0.323
1.501HisArg: 1.501 ± 0.655
2.702HisSer: 2.702 ± 1.22
0.6HisThr: 0.6 ± 0.88
0.901HisVal: 0.901 ± 0.324
0.0HisTrp: 0.0 ± 0.0
1.201HisTyr: 1.201 ± 1.153
0.0HisXaa: 0.0 ± 0.0
Ile
1.501IleAla: 1.501 ± 0.709
2.101IleCys: 2.101 ± 1.083
2.101IleAsp: 2.101 ± 0.636
4.203IleGlu: 4.203 ± 0.977
1.801IlePhe: 1.801 ± 0.609
2.101IleGly: 2.101 ± 0.947
1.501IleHis: 1.501 ± 1.026
1.501IleIle: 1.501 ± 0.232
4.503IleLys: 4.503 ± 0.904
7.205IleLeu: 7.205 ± 1.055
1.201IleMet: 1.201 ± 0.351
2.402IleAsn: 2.402 ± 0.744
2.702IlePro: 2.702 ± 0.402
2.101IleGln: 2.101 ± 0.284
3.302IleArg: 3.302 ± 0.588
3.002IleSer: 3.002 ± 0.497
4.203IleThr: 4.203 ± 0.843
4.203IleVal: 4.203 ± 0.787
0.3IleTrp: 0.3 ± 0.43
0.6IleTyr: 0.6 ± 0.323
0.0IleXaa: 0.0 ± 0.0
Lys
2.101LysAla: 2.101 ± 0.636
2.702LysCys: 2.702 ± 2.256
3.603LysAsp: 3.603 ± 1.213
6.304LysGlu: 6.304 ± 1.078
3.302LysPhe: 3.302 ± 1.342
4.503LysGly: 4.503 ± 1.32
0.3LysHis: 0.3 ± 0.44
3.603LysIle: 3.603 ± 1.028
5.404LysLys: 5.404 ± 1.275
8.406LysLeu: 8.406 ± 2.405
1.501LysMet: 1.501 ± 0.473
3.603LysAsn: 3.603 ± 2.289
2.402LysPro: 2.402 ± 0.415
1.501LysGln: 1.501 ± 0.473
3.603LysArg: 3.603 ± 0.682
6.304LysSer: 6.304 ± 1.695
4.203LysThr: 4.203 ± 1.307
4.803LysVal: 4.803 ± 0.829
0.901LysTrp: 0.901 ± 0.484
1.801LysTyr: 1.801 ± 0.586
0.0LysXaa: 0.0 ± 0.0
Leu
4.803LeuAla: 4.803 ± 0.905
4.203LeuCys: 4.203 ± 2.17
8.106LeuAsp: 8.106 ± 1.498
6.905LeuGlu: 6.905 ± 1.356
3.603LeuPhe: 3.603 ± 1.127
7.205LeuGly: 7.205 ± 0.961
1.801LeuHis: 1.801 ± 0.602
7.805LeuIle: 7.805 ± 1.25
10.507LeuLys: 10.507 ± 1.854
15.311LeuLeu: 15.311 ± 4.068
2.402LeuMet: 2.402 ± 0.411
8.106LeuAsn: 8.106 ± 1.335
3.903LeuPro: 3.903 ± 1.379
2.702LeuGln: 2.702 ± 0.561
6.304LeuArg: 6.304 ± 0.601
14.41LeuSer: 14.41 ± 3.684
6.004LeuThr: 6.004 ± 1.059
9.006LeuVal: 9.006 ± 1.937
1.201LeuTrp: 1.201 ± 0.351
2.402LeuTyr: 2.402 ± 1.013
0.0LeuXaa: 0.0 ± 0.0
Met
1.801MetAla: 1.801 ± 0.586
0.3MetCys: 0.3 ± 0.161
0.901MetAsp: 0.901 ± 0.754
0.901MetGlu: 0.901 ± 0.484
0.901MetPhe: 0.901 ± 1.29
2.101MetGly: 2.101 ± 0.979
0.901MetHis: 0.901 ± 0.484
0.6MetIle: 0.6 ± 0.323
1.201MetLys: 1.201 ± 0.351
3.302MetLeu: 3.302 ± 1.665
0.901MetMet: 0.901 ± 0.369
1.201MetAsn: 1.201 ± 0.351
0.6MetPro: 0.6 ± 0.636
0.3MetGln: 0.3 ± 0.43
1.801MetArg: 1.801 ± 0.609
3.002MetSer: 3.002 ± 0.715
0.901MetThr: 0.901 ± 0.303
0.6MetVal: 0.6 ± 0.323
0.0MetTrp: 0.0 ± 0.0
1.201MetTyr: 1.201 ± 0.351
0.0MetXaa: 0.0 ± 0.0
Asn
1.501AsnAla: 1.501 ± 1.282
0.3AsnCys: 0.3 ± 1.173
1.501AsnAsp: 1.501 ± 0.73
2.101AsnGlu: 2.101 ± 0.678
3.002AsnPhe: 3.002 ± 0.454
3.302AsnGly: 3.302 ± 0.776
0.6AsnHis: 0.6 ± 0.88
1.801AsnIle: 1.801 ± 1.132
3.302AsnLys: 3.302 ± 0.405
7.205AsnLeu: 7.205 ± 0.402
0.6AsnMet: 0.6 ± 0.636
3.002AsnAsn: 3.002 ± 1.418
2.101AsnPro: 2.101 ± 0.998
2.101AsnGln: 2.101 ± 0.512
1.801AsnArg: 1.801 ± 0.586
5.704AsnSer: 5.704 ± 2.033
3.002AsnThr: 3.002 ± 1.311
3.603AsnVal: 3.603 ± 0.873
0.3AsnTrp: 0.3 ± 0.161
2.402AsnTyr: 2.402 ± 0.933
0.0AsnXaa: 0.0 ± 0.0
Pro
0.6ProAla: 0.6 ± 0.335
0.901ProCys: 0.901 ± 0.324
2.702ProAsp: 2.702 ± 1.031
3.002ProGlu: 3.002 ± 2.184
1.501ProPhe: 1.501 ± 0.807
1.501ProGly: 1.501 ± 0.709
0.901ProHis: 0.901 ± 0.993
2.101ProIle: 2.101 ± 0.284
3.002ProLys: 3.002 ± 0.497
3.302ProLeu: 3.302 ± 1.045
0.6ProMet: 0.6 ± 0.323
1.801ProAsn: 1.801 ± 1.006
1.501ProPro: 1.501 ± 1.026
0.901ProGln: 0.901 ± 0.303
1.501ProArg: 1.501 ± 1.12
3.603ProSer: 3.603 ± 2.104
4.803ProThr: 4.803 ± 1.855
2.402ProVal: 2.402 ± 0.411
0.0ProTrp: 0.0 ± 0.0
1.201ProTyr: 1.201 ± 0.847
0.0ProXaa: 0.0 ± 0.0
Gln
1.501GlnAla: 1.501 ± 0.709
0.901GlnCys: 0.901 ± 0.779
0.901GlnAsp: 0.901 ± 0.779
1.801GlnGlu: 1.801 ± 0.606
0.901GlnPhe: 0.901 ± 0.303
2.402GlnGly: 2.402 ± 1.168
0.0GlnHis: 0.0 ± 0.0
2.402GlnIle: 2.402 ± 0.703
2.101GlnLys: 2.101 ± 1.083
4.503GlnLeu: 4.503 ± 0.904
0.0GlnMet: 0.0 ± 0.0
1.201GlnAsn: 1.201 ± 0.67
1.501GlnPro: 1.501 ± 0.618
0.901GlnGln: 0.901 ± 0.754
2.101GlnArg: 2.101 ± 0.636
3.603GlnSer: 3.603 ± 1.213
1.801GlnThr: 1.801 ± 0.602
3.302GlnVal: 3.302 ± 0.551
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
1.801ArgAla: 1.801 ± 1.006
1.501ArgCys: 1.501 ± 1.358
1.501ArgAsp: 1.501 ± 0.232
3.903ArgGlu: 3.903 ± 1.145
2.702ArgPhe: 2.702 ± 0.971
1.801ArgGly: 1.801 ± 0.606
1.501ArgHis: 1.501 ± 0.73
1.201ArgIle: 1.201 ± 0.345
3.903ArgLys: 3.903 ± 1.053
8.706ArgLeu: 8.706 ± 1.347
0.3ArgMet: 0.3 ± 0.43
3.002ArgAsn: 3.002 ± 1.271
1.501ArgPro: 1.501 ± 0.618
1.201ArgGln: 1.201 ± 0.372
2.702ArgArg: 2.702 ± 0.989
2.702ArgSer: 2.702 ± 0.565
1.801ArgThr: 1.801 ± 0.999
3.002ArgVal: 3.002 ± 1.197
1.201ArgTrp: 1.201 ± 0.345
2.101ArgTyr: 2.101 ± 1.218
0.0ArgXaa: 0.0 ± 0.0
Ser
3.903SerAla: 3.903 ± 0.876
1.801SerCys: 1.801 ± 0.602
6.605SerAsp: 6.605 ± 1.83
7.505SerGlu: 7.505 ± 2.673
2.702SerPhe: 2.702 ± 0.846
3.302SerGly: 3.302 ± 0.776
1.801SerHis: 1.801 ± 0.609
3.603SerIle: 3.603 ± 1.028
6.905SerLys: 6.905 ± 1.629
11.708SerLeu: 11.708 ± 0.82
2.702SerMet: 2.702 ± 0.797
4.203SerAsn: 4.203 ± 1.0
3.603SerPro: 3.603 ± 0.754
2.402SerGln: 2.402 ± 1.275
4.203SerArg: 4.203 ± 1.25
7.505SerSer: 7.505 ± 2.71
1.801SerThr: 1.801 ± 0.586
6.004SerVal: 6.004 ± 1.07
0.901SerTrp: 0.901 ± 0.485
3.903SerTyr: 3.903 ± 0.789
0.0SerXaa: 0.0 ± 0.0
Thr
1.201ThrAla: 1.201 ± 1.448
1.801ThrCys: 1.801 ± 1.156
3.603ThrAsp: 3.603 ± 0.673
2.702ThrGlu: 2.702 ± 1.071
2.101ThrPhe: 2.101 ± 0.743
2.702ThrGly: 2.702 ± 0.797
0.901ThrHis: 0.901 ± 1.319
3.903ThrIle: 3.903 ± 1.053
4.503ThrLys: 4.503 ± 0.56
5.404ThrLeu: 5.404 ± 0.609
1.201ThrMet: 1.201 ± 0.351
2.101ThrAsn: 2.101 ± 1.0
2.101ThrPro: 2.101 ± 0.284
2.101ThrGln: 2.101 ± 0.997
2.101ThrArg: 2.101 ± 0.743
3.603ThrSer: 3.603 ± 0.673
2.402ThrThr: 2.402 ± 0.972
3.603ThrVal: 3.603 ± 2.361
0.901ThrTrp: 0.901 ± 0.779
0.3ThrTyr: 0.3 ± 0.161
0.0ThrXaa: 0.0 ± 0.0
Val
4.503ValAla: 4.503 ± 1.42
1.201ValCys: 1.201 ± 0.645
3.302ValAsp: 3.302 ± 0.776
5.104ValGlu: 5.104 ± 1.827
3.302ValPhe: 3.302 ± 0.405
4.803ValGly: 4.803 ± 1.099
1.201ValHis: 1.201 ± 0.345
3.302ValIle: 3.302 ± 0.982
4.503ValLys: 4.503 ± 1.356
9.307ValLeu: 9.307 ± 2.737
2.101ValMet: 2.101 ± 0.979
4.203ValAsn: 4.203 ± 1.357
3.302ValPro: 3.302 ± 0.936
3.002ValGln: 3.002 ± 1.676
2.702ValArg: 2.702 ± 0.797
5.404ValSer: 5.404 ± 1.562
2.402ValThr: 2.402 ± 1.354
3.002ValVal: 3.002 ± 0.465
0.901ValTrp: 0.901 ± 0.485
1.501ValTyr: 1.501 ± 0.807
0.0ValXaa: 0.0 ± 0.0
Trp
0.901TrpAla: 0.901 ± 0.484
0.3TrpCys: 0.3 ± 0.161
1.201TrpAsp: 1.201 ± 0.67
0.901TrpGlu: 0.901 ± 1.369
0.6TrpPhe: 0.6 ± 1.124
0.3TrpGly: 0.3 ± 0.161
0.3TrpHis: 0.3 ± 0.161
0.6TrpIle: 0.6 ± 0.88
0.901TrpLys: 0.901 ± 0.779
1.801TrpLeu: 1.801 ± 0.602
0.6TrpMet: 0.6 ± 0.636
0.0TrpAsn: 0.0 ± 0.0
0.6TrpPro: 0.6 ± 0.335
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.6TrpSer: 0.6 ± 0.88
0.901TrpThr: 0.901 ± 0.485
0.3TrpVal: 0.3 ± 0.161
0.0TrpTrp: 0.0 ± 0.0
0.6TrpTyr: 0.6 ± 0.351
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.6TyrAla: 0.6 ± 0.323
1.501TyrCys: 1.501 ± 0.655
0.6TyrAsp: 0.6 ± 0.323
3.002TyrGlu: 3.002 ± 1.186
0.6TyrPhe: 0.6 ± 0.323
1.201TyrGly: 1.201 ± 1.093
0.6TyrHis: 0.6 ± 0.323
1.801TyrIle: 1.801 ± 0.609
1.801TyrLys: 1.801 ± 0.586
2.702TyrLeu: 2.702 ± 1.163
0.3TyrMet: 0.3 ± 0.43
1.501TyrAsn: 1.501 ± 1.026
0.901TyrPro: 0.901 ± 0.303
1.201TyrGln: 1.201 ± 0.372
2.101TyrArg: 2.101 ± 0.743
2.702TyrSer: 2.702 ± 0.836
2.101TyrThr: 2.101 ± 0.512
2.402TyrVal: 2.402 ± 0.411
0.0TyrTrp: 0.0 ± 0.0
0.3TyrTyr: 0.3 ± 0.161
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3332 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski