Amino acid dipepetide frequency for Beihai tombus-like virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.0AlaAla: 0.0 ± 0.0
1.027AlaCys: 1.027 ± 1.188
1.027AlaAsp: 1.027 ± 1.188
3.08AlaGlu: 3.08 ± 0.016
3.08AlaPhe: 3.08 ± 1.774
1.027AlaGly: 1.027 ± 0.602
2.053AlaHis: 2.053 ± 1.203
8.214AlaIle: 8.214 ± 2.344
6.16AlaLys: 6.16 ± 1.821
4.107AlaLeu: 4.107 ± 1.172
2.053AlaMet: 2.053 ± 0.957
2.053AlaAsn: 2.053 ± 0.586
1.027AlaPro: 1.027 ± 0.602
2.053AlaGln: 2.053 ± 0.586
5.133AlaArg: 5.133 ± 0.57
1.027AlaSer: 1.027 ± 1.188
6.16AlaThr: 6.16 ± 1.758
5.133AlaVal: 5.133 ± 0.57
1.027AlaTrp: 1.027 ± 1.188
4.107AlaTyr: 4.107 ± 0.617
0.0AlaXaa: 0.0 ± 0.0
Cys
2.053CysAla: 2.053 ± 0.586
1.027CysCys: 1.027 ± 0.602
1.027CysAsp: 1.027 ± 0.602
0.0CysGlu: 0.0 ± 0.0
1.027CysPhe: 1.027 ± 1.188
2.053CysGly: 2.053 ± 0.586
1.027CysHis: 1.027 ± 0.602
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
4.107CysLeu: 4.107 ± 0.617
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
2.053CysGln: 2.053 ± 0.586
3.08CysArg: 3.08 ± 1.774
0.0CysSer: 0.0 ± 0.0
1.027CysThr: 1.027 ± 1.188
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.053AspAla: 2.053 ± 0.586
0.0AspCys: 0.0 ± 0.0
1.027AspAsp: 1.027 ± 0.602
2.053AspGlu: 2.053 ± 2.376
1.027AspPhe: 1.027 ± 0.602
3.08AspGly: 3.08 ± 1.805
0.0AspHis: 0.0 ± 0.0
2.053AspIle: 2.053 ± 0.586
4.107AspLys: 4.107 ± 2.407
5.133AspLeu: 5.133 ± 0.57
4.107AspMet: 4.107 ± 2.407
0.0AspAsn: 0.0 ± 0.0
2.053AspPro: 2.053 ± 1.203
5.133AspGln: 5.133 ± 1.219
5.133AspArg: 5.133 ± 1.219
0.0AspSer: 0.0 ± 0.0
1.027AspThr: 1.027 ± 0.602
5.133AspVal: 5.133 ± 1.219
1.027AspTrp: 1.027 ± 0.602
1.027AspTyr: 1.027 ± 0.602
0.0AspXaa: 0.0 ± 0.0
Glu
4.107GluAla: 4.107 ± 1.172
0.0GluCys: 0.0 ± 0.0
3.08GluAsp: 3.08 ± 0.016
5.133GluGlu: 5.133 ± 1.219
3.08GluPhe: 3.08 ± 1.805
4.107GluGly: 4.107 ± 2.407
2.053GluHis: 2.053 ± 1.203
4.107GluIle: 4.107 ± 0.617
3.08GluLys: 3.08 ± 1.774
4.107GluLeu: 4.107 ± 0.617
4.107GluMet: 4.107 ± 1.172
1.027GluAsn: 1.027 ± 0.602
1.027GluPro: 1.027 ± 1.188
4.107GluGln: 4.107 ± 0.617
3.08GluArg: 3.08 ± 1.774
4.107GluSer: 4.107 ± 0.617
2.053GluThr: 2.053 ± 0.586
3.08GluVal: 3.08 ± 0.016
0.0GluTrp: 0.0 ± 0.0
4.107GluTyr: 4.107 ± 0.617
0.0GluXaa: 0.0 ± 0.0
Phe
2.053PheAla: 2.053 ± 0.586
1.027PheCys: 1.027 ± 0.602
4.107PheAsp: 4.107 ± 0.617
3.08PheGlu: 3.08 ± 0.016
3.08PhePhe: 3.08 ± 0.016
1.027PheGly: 1.027 ± 0.602
1.027PheHis: 1.027 ± 0.602
2.053PheIle: 2.053 ± 1.203
7.187PheLys: 7.187 ± 1.157
5.133PheLeu: 5.133 ± 0.57
0.0PheMet: 0.0 ± 0.0
1.027PheAsn: 1.027 ± 0.602
0.0PhePro: 0.0 ± 0.0
2.053PheGln: 2.053 ± 0.586
7.187PheArg: 7.187 ± 0.633
2.053PheSer: 2.053 ± 0.586
1.027PheThr: 1.027 ± 1.188
2.053PheVal: 2.053 ± 0.586
0.0PheTrp: 0.0 ± 0.0
2.053PheTyr: 2.053 ± 1.203
0.0PheXaa: 0.0 ± 0.0
Gly
3.08GlyAla: 3.08 ± 0.016
1.027GlyCys: 1.027 ± 0.602
4.107GlyAsp: 4.107 ± 0.617
0.0GlyGlu: 0.0 ± 0.0
1.027GlyPhe: 1.027 ± 0.602
3.08GlyGly: 3.08 ± 0.016
1.027GlyHis: 1.027 ± 1.188
1.027GlyIle: 1.027 ± 0.602
5.133GlyLys: 5.133 ± 0.57
4.107GlyLeu: 4.107 ± 0.617
1.027GlyMet: 1.027 ± 1.188
2.053GlyAsn: 2.053 ± 1.203
1.027GlyPro: 1.027 ± 1.188
2.053GlyGln: 2.053 ± 0.586
2.053GlyArg: 2.053 ± 0.586
3.08GlySer: 3.08 ± 1.805
2.053GlyThr: 2.053 ± 2.376
9.24GlyVal: 9.24 ± 0.047
1.027GlyTrp: 1.027 ± 1.188
1.027GlyTyr: 1.027 ± 0.602
0.0GlyXaa: 0.0 ± 0.0
His
3.08HisAla: 3.08 ± 0.016
1.027HisCys: 1.027 ± 0.602
0.0HisAsp: 0.0 ± 0.0
2.053HisGlu: 2.053 ± 0.586
1.027HisPhe: 1.027 ± 0.602
1.027HisGly: 1.027 ± 1.188
0.0HisHis: 0.0 ± 0.0
2.053HisIle: 2.053 ± 0.586
2.053HisLys: 2.053 ± 0.586
2.053HisLeu: 2.053 ± 0.586
0.0HisMet: 0.0 ± 0.0
1.027HisAsn: 1.027 ± 0.602
2.053HisPro: 2.053 ± 1.203
0.0HisGln: 0.0 ± 0.0
1.027HisArg: 1.027 ± 0.602
0.0HisSer: 0.0 ± 0.0
2.053HisThr: 2.053 ± 1.203
1.027HisVal: 1.027 ± 1.188
1.027HisTrp: 1.027 ± 1.188
1.027HisTyr: 1.027 ± 0.602
0.0HisXaa: 0.0 ± 0.0
Ile
5.133IleAla: 5.133 ± 2.36
0.0IleCys: 0.0 ± 0.0
2.053IleAsp: 2.053 ± 1.203
6.16IleGlu: 6.16 ± 1.821
4.107IlePhe: 4.107 ± 1.172
1.027IleGly: 1.027 ± 0.602
0.0IleHis: 0.0 ± 0.0
2.053IleIle: 2.053 ± 0.586
6.16IleLys: 6.16 ± 0.031
5.133IleLeu: 5.133 ± 0.57
3.08IleMet: 3.08 ± 1.805
1.027IleAsn: 1.027 ± 0.602
7.187IlePro: 7.187 ± 0.633
2.053IleGln: 2.053 ± 1.203
5.133IleArg: 5.133 ± 4.149
3.08IleSer: 3.08 ± 1.805
3.08IleThr: 3.08 ± 0.016
4.107IleVal: 4.107 ± 2.962
0.0IleTrp: 0.0 ± 0.0
5.133IleTyr: 5.133 ± 1.219
0.0IleXaa: 0.0 ± 0.0
Lys
5.133LysAla: 5.133 ± 0.57
1.027LysCys: 1.027 ± 0.602
3.08LysAsp: 3.08 ± 1.805
3.08LysGlu: 3.08 ± 1.774
2.053LysPhe: 2.053 ± 1.203
3.08LysGly: 3.08 ± 0.016
2.053LysHis: 2.053 ± 1.203
7.187LysIle: 7.187 ± 1.157
4.107LysLys: 4.107 ± 2.407
6.16LysLeu: 6.16 ± 3.548
5.133LysMet: 5.133 ± 0.57
2.053LysAsn: 2.053 ± 1.203
7.187LysPro: 7.187 ± 2.422
0.0LysGln: 0.0 ± 0.0
9.24LysArg: 9.24 ± 1.836
2.053LysSer: 2.053 ± 1.203
2.053LysThr: 2.053 ± 1.203
10.267LysVal: 10.267 ± 6.509
1.027LysTrp: 1.027 ± 0.602
4.107LysTyr: 4.107 ± 1.172
0.0LysXaa: 0.0 ± 0.0
Leu
4.107LeuAla: 4.107 ± 4.751
1.027LeuCys: 1.027 ± 1.188
1.027LeuAsp: 1.027 ± 0.602
7.187LeuGlu: 7.187 ± 2.422
6.16LeuPhe: 6.16 ± 0.031
5.133LeuGly: 5.133 ± 2.36
2.053LeuHis: 2.053 ± 0.586
1.027LeuIle: 1.027 ± 1.188
6.16LeuLys: 6.16 ± 1.758
5.133LeuLeu: 5.133 ± 0.57
5.133LeuMet: 5.133 ± 2.36
4.107LeuAsn: 4.107 ± 0.617
6.16LeuPro: 6.16 ± 1.821
5.133LeuGln: 5.133 ± 0.57
5.133LeuArg: 5.133 ± 2.36
5.133LeuSer: 5.133 ± 1.219
3.08LeuThr: 3.08 ± 0.016
8.214LeuVal: 8.214 ± 0.555
0.0LeuTrp: 0.0 ± 0.0
1.027LeuTyr: 1.027 ± 0.602
0.0LeuXaa: 0.0 ± 0.0
Met
2.053MetAla: 2.053 ± 0.586
1.027MetCys: 1.027 ± 0.602
1.027MetAsp: 1.027 ± 0.602
2.053MetGlu: 2.053 ± 0.586
2.053MetPhe: 2.053 ± 1.203
0.0MetGly: 0.0 ± 0.0
1.027MetHis: 1.027 ± 1.188
1.027MetIle: 1.027 ± 0.602
2.053MetLys: 2.053 ± 2.376
4.107MetLeu: 4.107 ± 1.172
0.0MetMet: 0.0 ± 0.0
3.08MetAsn: 3.08 ± 0.016
0.0MetPro: 0.0 ± 0.0
1.027MetGln: 1.027 ± 1.188
0.0MetArg: 0.0 ± 0.0
5.133MetSer: 5.133 ± 1.219
2.053MetThr: 2.053 ± 0.586
1.027MetVal: 1.027 ± 0.602
3.08MetTrp: 3.08 ± 1.805
1.027MetTyr: 1.027 ± 1.188
0.0MetXaa: 0.0 ± 0.0
Asn
2.053AsnAla: 2.053 ± 2.376
0.0AsnCys: 0.0 ± 0.0
2.053AsnAsp: 2.053 ± 1.203
0.0AsnGlu: 0.0 ± 0.0
1.027AsnPhe: 1.027 ± 0.602
0.0AsnGly: 0.0 ± 0.0
3.08AsnHis: 3.08 ± 1.774
2.053AsnIle: 2.053 ± 1.203
2.053AsnLys: 2.053 ± 1.203
3.08AsnLeu: 3.08 ± 1.805
1.027AsnMet: 1.027 ± 0.34
2.053AsnAsn: 2.053 ± 1.203
1.027AsnPro: 1.027 ± 0.602
0.0AsnGln: 0.0 ± 0.0
1.027AsnArg: 1.027 ± 0.602
3.08AsnSer: 3.08 ± 1.805
2.053AsnThr: 2.053 ± 1.203
3.08AsnVal: 3.08 ± 0.016
1.027AsnTrp: 1.027 ± 0.602
1.027AsnTyr: 1.027 ± 1.188
0.0AsnXaa: 0.0 ± 0.0
Pro
1.027ProAla: 1.027 ± 0.602
0.0ProCys: 0.0 ± 0.0
0.0ProAsp: 0.0 ± 0.0
3.08ProGlu: 3.08 ± 0.016
1.027ProPhe: 1.027 ± 0.602
3.08ProGly: 3.08 ± 1.805
0.0ProHis: 0.0 ± 0.0
3.08ProIle: 3.08 ± 1.805
2.053ProLys: 2.053 ± 1.203
2.053ProLeu: 2.053 ± 0.586
0.0ProMet: 0.0 ± 0.0
2.053ProAsn: 2.053 ± 1.203
2.053ProPro: 2.053 ± 0.586
0.0ProGln: 0.0 ± 0.0
7.187ProArg: 7.187 ± 4.212
7.187ProSer: 7.187 ± 0.633
4.107ProThr: 4.107 ± 1.172
6.16ProVal: 6.16 ± 0.031
2.053ProTrp: 2.053 ± 1.203
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
4.107GlnAla: 4.107 ± 0.617
1.027GlnCys: 1.027 ± 1.188
2.053GlnAsp: 2.053 ± 1.203
2.053GlnGlu: 2.053 ± 0.586
3.08GlnPhe: 3.08 ± 0.016
1.027GlnGly: 1.027 ± 1.188
1.027GlnHis: 1.027 ± 0.602
5.133GlnIle: 5.133 ± 2.36
2.053GlnLys: 2.053 ± 1.203
4.107GlnLeu: 4.107 ± 2.962
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
1.027GlnPro: 1.027 ± 0.602
1.027GlnGln: 1.027 ± 0.602
4.107GlnArg: 4.107 ± 1.172
1.027GlnSer: 1.027 ± 1.188
1.027GlnThr: 1.027 ± 0.602
1.027GlnVal: 1.027 ± 0.602
0.0GlnTrp: 0.0 ± 0.0
1.027GlnTyr: 1.027 ± 0.602
0.0GlnXaa: 0.0 ± 0.0
Arg
6.16ArgAla: 6.16 ± 0.031
3.08ArgCys: 3.08 ± 3.563
2.053ArgAsp: 2.053 ± 1.203
3.08ArgGlu: 3.08 ± 1.805
5.133ArgPhe: 5.133 ± 0.57
4.107ArgGly: 4.107 ± 2.962
3.08ArgHis: 3.08 ± 0.016
3.08ArgIle: 3.08 ± 1.805
7.187ArgLys: 7.187 ± 0.633
4.107ArgLeu: 4.107 ± 1.172
3.08ArgMet: 3.08 ± 0.016
2.053ArgAsn: 2.053 ± 0.586
4.107ArgPro: 4.107 ± 0.617
3.08ArgGln: 3.08 ± 0.016
10.267ArgArg: 10.267 ± 1.141
6.16ArgSer: 6.16 ± 3.61
4.107ArgThr: 4.107 ± 2.962
7.187ArgVal: 7.187 ± 1.157
1.027ArgTrp: 1.027 ± 0.602
4.107ArgTyr: 4.107 ± 2.407
0.0ArgXaa: 0.0 ± 0.0
Ser
5.133SerAla: 5.133 ± 3.008
0.0SerCys: 0.0 ± 0.0
3.08SerAsp: 3.08 ± 0.016
5.133SerGlu: 5.133 ± 3.008
3.08SerPhe: 3.08 ± 0.016
2.053SerGly: 2.053 ± 0.586
0.0SerHis: 0.0 ± 0.0
3.08SerIle: 3.08 ± 0.016
4.107SerLys: 4.107 ± 0.617
3.08SerLeu: 3.08 ± 1.805
1.027SerMet: 1.027 ± 1.188
2.053SerAsn: 2.053 ± 0.586
4.107SerPro: 4.107 ± 2.407
3.08SerGln: 3.08 ± 1.774
7.187SerArg: 7.187 ± 2.422
4.107SerSer: 4.107 ± 2.407
0.0SerThr: 0.0 ± 0.0
2.053SerVal: 2.053 ± 0.586
2.053SerTrp: 2.053 ± 1.203
3.08SerTyr: 3.08 ± 0.016
0.0SerXaa: 0.0 ± 0.0
Thr
4.107ThrAla: 4.107 ± 0.617
1.027ThrCys: 1.027 ± 0.602
3.08ThrAsp: 3.08 ± 1.774
1.027ThrGlu: 1.027 ± 1.188
2.053ThrPhe: 2.053 ± 0.586
3.08ThrGly: 3.08 ± 1.774
1.027ThrHis: 1.027 ± 1.188
5.133ThrIle: 5.133 ± 1.219
3.08ThrLys: 3.08 ± 0.016
5.133ThrLeu: 5.133 ± 0.57
1.027ThrMet: 1.027 ± 0.602
3.08ThrAsn: 3.08 ± 0.016
3.08ThrPro: 3.08 ± 0.016
2.053ThrGln: 2.053 ± 2.376
1.027ThrArg: 1.027 ± 0.602
3.08ThrSer: 3.08 ± 1.805
0.0ThrThr: 0.0 ± 0.0
2.053ThrVal: 2.053 ± 1.203
1.027ThrTrp: 1.027 ± 1.188
3.08ThrTyr: 3.08 ± 0.016
0.0ThrXaa: 0.0 ± 0.0
Val
3.08ValAla: 3.08 ± 0.016
4.107ValCys: 4.107 ± 0.617
4.107ValAsp: 4.107 ± 0.617
7.187ValGlu: 7.187 ± 1.157
2.053ValPhe: 2.053 ± 0.586
8.214ValGly: 8.214 ± 0.555
0.0ValHis: 0.0 ± 0.0
7.187ValIle: 7.187 ± 2.946
7.187ValLys: 7.187 ± 1.157
6.16ValLeu: 6.16 ± 3.548
0.0ValMet: 0.0 ± 0.0
0.0ValAsn: 0.0 ± 0.0
3.08ValPro: 3.08 ± 1.805
1.027ValGln: 1.027 ± 0.602
3.08ValArg: 3.08 ± 1.805
5.133ValSer: 5.133 ± 4.149
8.214ValThr: 8.214 ± 1.235
4.107ValVal: 4.107 ± 2.962
0.0ValTrp: 0.0 ± 0.0
2.053ValTyr: 2.053 ± 2.376
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
2.053TrpAsp: 2.053 ± 1.203
2.053TrpGlu: 2.053 ± 1.203
1.027TrpPhe: 1.027 ± 1.188
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
3.08TrpIle: 3.08 ± 1.805
0.0TrpLys: 0.0 ± 0.0
3.08TrpLeu: 3.08 ± 1.805
1.027TrpMet: 1.027 ± 1.188
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
2.053TrpArg: 2.053 ± 2.376
1.027TrpSer: 1.027 ± 0.602
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.027TyrAla: 1.027 ± 0.602
1.027TyrCys: 1.027 ± 1.188
5.133TyrAsp: 5.133 ± 1.219
2.053TyrGlu: 2.053 ± 0.586
1.027TyrPhe: 1.027 ± 0.602
2.053TyrGly: 2.053 ± 1.203
3.08TyrHis: 3.08 ± 0.016
3.08TyrIle: 3.08 ± 0.016
6.16TyrLys: 6.16 ± 1.758
2.053TyrLeu: 2.053 ± 0.586
0.0TyrMet: 0.0 ± 0.0
3.08TyrAsn: 3.08 ± 0.016
0.0TyrPro: 0.0 ± 0.0
0.0TyrGln: 0.0 ± 0.0
4.107TyrArg: 4.107 ± 0.617
1.027TyrSer: 1.027 ± 0.602
3.08TyrThr: 3.08 ± 1.805
1.027TyrVal: 1.027 ± 0.602
0.0TyrTrp: 0.0 ± 0.0
2.053TyrTyr: 2.053 ± 1.203
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (975 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski