Bat coronavirus Cp/Yunnan2011

Taxonomy: Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes; Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae; Betacoronavirus; Sarbecovirus; Severe acute respiratory syndrome-related coronavirus

Average proteome isoelectric point is 6.6

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|R9QTJ3|R9QTJ3_SARS ORF3 protein OS=Bat coronavirus Cp/Yunnan2011 OX=1283333 PE=4 SV=1
MM1 pKa = 7.73KK2 pKa = 10.3IFLFSLLFSAALAQEE17 pKa = 4.63GCGLLSFKK25 pKa = 10.04PQPKK29 pKa = 9.57LAQFSSSKK37 pKa = 10.5RR38 pKa = 11.84GVYY41 pKa = 10.72YY42 pKa = 10.63NDD44 pKa = 4.77DD45 pKa = 3.51IFRR48 pKa = 11.84SDD50 pKa = 3.84VLHH53 pKa = 6.33LTQDD57 pKa = 3.37YY58 pKa = 9.62FLPFHH63 pKa = 7.26SNLTQYY69 pKa = 10.92FSLNVDD75 pKa = 3.27SDD77 pKa = 3.82RR78 pKa = 11.84QVYY81 pKa = 9.95FDD83 pKa = 4.64NPTLNFGDD91 pKa = 3.83GVYY94 pKa = 10.25FAATEE99 pKa = 3.92KK100 pKa = 11.13SNVIRR105 pKa = 11.84GWIFGSTMDD114 pKa = 4.87NSTQSAIIVNNSTHH128 pKa = 7.21IIIRR132 pKa = 11.84VCNFNLCKK140 pKa = 10.5EE141 pKa = 4.14PMFTVSRR148 pKa = 11.84GVHH151 pKa = 5.37FSSWVYY157 pKa = 10.31QSAFNCTYY165 pKa = 11.31DD166 pKa = 3.42RR167 pKa = 11.84VEE169 pKa = 5.14KK170 pKa = 10.81SFQLDD175 pKa = 3.62TAPKK179 pKa = 8.49TGNFKK184 pKa = 10.73DD185 pKa = 3.24LRR187 pKa = 11.84EE188 pKa = 4.05YY189 pKa = 10.89VFKK192 pKa = 11.26NRR194 pKa = 11.84DD195 pKa = 3.16GFLSVYY201 pKa = 10.32HH202 pKa = 7.0SYY204 pKa = 10.57TPVDD208 pKa = 4.42IIRR211 pKa = 11.84GIPVGFSVLKK221 pKa = 10.32PILKK225 pKa = 10.31LPIGINITSFKK236 pKa = 11.08VVMTMYY242 pKa = 10.76SQTTSNFLSEE252 pKa = 3.95SAAYY256 pKa = 10.04YY257 pKa = 10.23VGNLKK262 pKa = 10.56YY263 pKa = 9.83VTFMFQFNEE272 pKa = 3.9NGTIADD278 pKa = 4.89AVDD281 pKa = 4.35CSQNPLAEE289 pKa = 4.46LKK291 pKa = 9.51CTLKK295 pKa = 10.83NFNVSKK301 pKa = 10.97GIYY304 pKa = 6.16QTSNFRR310 pKa = 11.84VSPSTEE316 pKa = 3.7VIRR319 pKa = 11.84FPNITNRR326 pKa = 11.84CPFDD330 pKa = 3.58RR331 pKa = 11.84VFNASRR337 pKa = 11.84FPSVYY342 pKa = 9.2AWEE345 pKa = 4.04RR346 pKa = 11.84TKK348 pKa = 10.81ISDD351 pKa = 3.69CVADD355 pKa = 3.7YY356 pKa = 9.98TVLYY360 pKa = 10.29NSTSFSTFKK369 pKa = 10.75CYY371 pKa = 10.03GVSPSKK377 pKa = 11.02LIDD380 pKa = 3.28LCFTSVYY387 pKa = 10.97ADD389 pKa = 3.22TFLIRR394 pKa = 11.84FSEE397 pKa = 4.39VRR399 pKa = 11.84QIAPGEE405 pKa = 4.15TGVIADD411 pKa = 4.42YY412 pKa = 10.83NYY414 pKa = 11.06KK415 pKa = 10.7LPDD418 pKa = 3.66EE419 pKa = 4.37FTGCVIAWNTANQDD433 pKa = 2.9RR434 pKa = 11.84GQYY437 pKa = 9.81YY438 pKa = 9.57YY439 pKa = 10.87RR440 pKa = 11.84SSRR443 pKa = 11.84KK444 pKa = 7.58TKK446 pKa = 10.3LKK448 pKa = 10.27PFEE451 pKa = 5.22RR452 pKa = 11.84DD453 pKa = 3.0LSSDD457 pKa = 3.51EE458 pKa = 4.18NGVRR462 pKa = 11.84TLSTYY467 pKa = 11.13DD468 pKa = 4.03FYY470 pKa = 11.17PSVPLEE476 pKa = 4.01YY477 pKa = 9.74QATRR481 pKa = 11.84VVVLSFEE488 pKa = 4.61LLNAPATVCGPKK500 pKa = 10.42LSTSLIKK507 pKa = 10.38NQCVNFNFNGLKK519 pKa = 9.11GTGVLTDD526 pKa = 3.51SSKK529 pKa = 11.0KK530 pKa = 9.96FQSFQQFGRR539 pKa = 11.84DD540 pKa = 3.18ASDD543 pKa = 3.34FTDD546 pKa = 3.68SVRR549 pKa = 11.84DD550 pKa = 3.75PQTLQILDD558 pKa = 3.94ISPCSFGGVSVITPGTNASSEE579 pKa = 4.47VAVLYY584 pKa = 10.73QDD586 pKa = 4.29VNCTDD591 pKa = 3.01VPTAIRR597 pKa = 11.84ADD599 pKa = 3.52QLTPAWRR606 pKa = 11.84VYY608 pKa = 10.25SAGVNVFQTQAGCLIGAEE626 pKa = 4.44HH627 pKa = 6.46VNASYY632 pKa = 11.03EE633 pKa = 4.01CDD635 pKa = 3.21IPIGAGICASYY646 pKa = 8.37HH647 pKa = 4.65TASLLRR653 pKa = 11.84NTGQKK658 pKa = 10.51SIVAYY663 pKa = 9.53TMSLGAEE670 pKa = 3.91NSIAYY675 pKa = 9.44ANNSIAIPTNFSISVTTEE693 pKa = 3.49VMPVSMAKK701 pKa = 9.66TSVDD705 pKa = 3.1CTMYY709 pKa = 10.34ICGDD713 pKa = 3.6SQEE716 pKa = 4.51CSNLLLQYY724 pKa = 11.24GSFCTQLNRR733 pKa = 11.84ALSGIAVEE741 pKa = 4.22QDD743 pKa = 2.97KK744 pKa = 8.86NTQEE748 pKa = 3.75VFAQVKK754 pKa = 9.11QMYY757 pKa = 7.06KK758 pKa = 9.37TPAIKK763 pKa = 10.61DD764 pKa = 3.33FGGFNFSQILPDD776 pKa = 3.66PSKK779 pKa = 8.47PTKK782 pKa = 10.11RR783 pKa = 11.84SFIEE787 pKa = 4.3DD788 pKa = 3.61LLFNKK793 pKa = 7.99VTLADD798 pKa = 3.57AGFMKK803 pKa = 10.37QYY805 pKa = 10.74GEE807 pKa = 4.27CLGDD811 pKa = 3.41ISARR815 pKa = 11.84DD816 pKa = 4.03LICAQKK822 pKa = 10.77FNGLTVLPPLLTDD835 pKa = 3.7EE836 pKa = 5.07MIAAYY841 pKa = 8.13TAALVSGTATAGWTFGAGAALQIPFAMQMAYY872 pKa = 10.08RR873 pKa = 11.84FNGIGVTQNVLYY885 pKa = 10.46EE886 pKa = 4.09NQKK889 pKa = 10.62QIANQFNKK897 pKa = 10.46AISQIQEE904 pKa = 4.19SLTTTSTALGKK915 pKa = 10.37LQDD918 pKa = 3.95VVNQNAQALNTLVKK932 pKa = 10.38QLSSNFGAISSVLNDD947 pKa = 3.17ILSRR951 pKa = 11.84LDD953 pKa = 3.31KK954 pKa = 11.45VEE956 pKa = 5.19AEE958 pKa = 4.28VQIDD962 pKa = 3.56RR963 pKa = 11.84LITGRR968 pKa = 11.84LQSLQTYY975 pKa = 7.4VTQQLIRR982 pKa = 11.84AAEE985 pKa = 3.85IRR987 pKa = 11.84ASANLAATKK996 pKa = 9.96MSEE999 pKa = 4.28CVLGQSKK1006 pKa = 10.12RR1007 pKa = 11.84VDD1009 pKa = 4.0FCGKK1013 pKa = 9.92GYY1015 pKa = 10.57HH1016 pKa = 6.84LMSFPQAAPHH1026 pKa = 5.76GVVFLHH1032 pKa = 5.25VTYY1035 pKa = 10.82VPSQEE1040 pKa = 4.9RR1041 pKa = 11.84NFTTAPAICHH1051 pKa = 5.3QGKK1054 pKa = 10.39AYY1056 pKa = 9.98FPRR1059 pKa = 11.84EE1060 pKa = 3.84GVFVSNGTSWFITQRR1075 pKa = 11.84NFFSPQIITTDD1086 pKa = 3.16NTFVSGNCDD1095 pKa = 3.2VVIGIINNTVYY1106 pKa = 10.97DD1107 pKa = 4.22PLQPEE1112 pKa = 4.19LDD1114 pKa = 3.85SFKK1117 pKa = 11.4EE1118 pKa = 3.91EE1119 pKa = 3.56LDD1121 pKa = 3.63KK1122 pKa = 11.53YY1123 pKa = 10.15FKK1125 pKa = 10.99NHH1127 pKa = 6.01TSPDD1131 pKa = 3.14VDD1133 pKa = 4.4LGDD1136 pKa = 3.31ISGINASVVNIQKK1149 pKa = 10.63EE1150 pKa = 3.92IDD1152 pKa = 3.67RR1153 pKa = 11.84LNEE1156 pKa = 3.5VAKK1159 pKa = 10.61NLNEE1163 pKa = 4.14SLIDD1167 pKa = 3.75LQEE1170 pKa = 4.17LGKK1173 pKa = 10.54YY1174 pKa = 6.98EE1175 pKa = 5.3QYY1177 pKa = 10.78IKK1179 pKa = 10.03WPWYY1183 pKa = 8.39VWLGFIAGLIAIVMATILLCCMTSCCSCLKK1213 pKa = 10.16GACSCGSCCKK1223 pKa = 10.16FDD1225 pKa = 4.43EE1226 pKa = 5.39DD1227 pKa = 5.38DD1228 pKa = 4.38SEE1230 pKa = 4.36PVLKK1234 pKa = 10.36GVKK1237 pKa = 9.35LHH1239 pKa = 5.3YY1240 pKa = 9.44TT1241 pKa = 3.44

Molecular weight: 137.65 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|R9QTB5|R9QTB5_SARS Membrane protein OS=Bat coronavirus Cp/Yunnan2011 OX=1283333 GN=M PE=3 SV=1
MM1 pKa = 7.79SDD3 pKa = 4.35NGPQQNQRR11 pKa = 11.84SAPRR15 pKa = 11.84ITFGGPTDD23 pKa = 4.07SADD26 pKa = 3.37NNQDD30 pKa = 3.01GGRR33 pKa = 11.84SGARR37 pKa = 11.84PKK39 pKa = 10.25QRR41 pKa = 11.84RR42 pKa = 11.84PQGLPNNTASWFTALTQHH60 pKa = 6.06GKK62 pKa = 10.36EE63 pKa = 3.96EE64 pKa = 4.07LRR66 pKa = 11.84FPRR69 pKa = 11.84GQGVPINTNSGKK81 pKa = 10.01DD82 pKa = 3.58DD83 pKa = 3.56QIGYY87 pKa = 8.17YY88 pKa = 9.92RR89 pKa = 11.84RR90 pKa = 11.84ATRR93 pKa = 11.84RR94 pKa = 11.84VRR96 pKa = 11.84GGDD99 pKa = 3.09GKK101 pKa = 10.39MKK103 pKa = 9.92EE104 pKa = 4.5LSPRR108 pKa = 11.84WYY110 pKa = 10.01FYY112 pKa = 11.5YY113 pKa = 10.73LGTGPEE119 pKa = 3.63ASLPYY124 pKa = 9.9GANKK128 pKa = 9.97EE129 pKa = 4.25GIVWVAIEE137 pKa = 4.45GALNTPKK144 pKa = 10.91DD145 pKa = 4.0HH146 pKa = 7.46IGTRR150 pKa = 11.84NPNNNAAIVLQLPQGTTLPKK170 pKa = 10.34GFYY173 pKa = 10.67AEE175 pKa = 4.5GSRR178 pKa = 11.84GGSQASSRR186 pKa = 11.84SSSRR190 pKa = 11.84SRR192 pKa = 11.84GNSRR196 pKa = 11.84NSTPGSSRR204 pKa = 11.84GNSPARR210 pKa = 11.84MASGGGEE217 pKa = 3.84TALALLLLDD226 pKa = 4.89RR227 pKa = 11.84LNQLEE232 pKa = 4.58SKK234 pKa = 10.86VSGKK238 pKa = 10.04GQQQQGQTVTKK249 pKa = 9.98KK250 pKa = 10.44SAAEE254 pKa = 3.73ASKK257 pKa = 10.76KK258 pKa = 9.61PRR260 pKa = 11.84QKK262 pKa = 9.66RR263 pKa = 11.84TATKK267 pKa = 10.12QYY269 pKa = 11.12NVTQAFGRR277 pKa = 11.84RR278 pKa = 11.84GPEE281 pKa = 3.4QTQGNFGDD289 pKa = 3.91QEE291 pKa = 4.91LIRR294 pKa = 11.84QGTDD298 pKa = 2.96YY299 pKa = 11.27KK300 pKa = 10.5HH301 pKa = 6.32WPQIAQFAPSASAFFGMSRR320 pKa = 11.84IGMEE324 pKa = 4.16VTPSGTWLTYY334 pKa = 10.42HH335 pKa = 7.06GAIKK339 pKa = 10.61LDD341 pKa = 4.18DD342 pKa = 4.89KK343 pKa = 11.64DD344 pKa = 3.91PQFKK348 pKa = 11.14DD349 pKa = 3.7NVILLNKK356 pKa = 10.01HH357 pKa = 4.67IDD359 pKa = 3.35AYY361 pKa = 9.77KK362 pKa = 9.88TFPPTEE368 pKa = 3.95PKK370 pKa = 9.88KK371 pKa = 10.6DD372 pKa = 3.48KK373 pKa = 10.73KK374 pKa = 10.99KK375 pKa = 9.88KK376 pKa = 8.29TDD378 pKa = 3.29EE379 pKa = 4.34AQPLPQRR386 pKa = 11.84QKK388 pKa = 10.35KK389 pKa = 8.88QPTVTLLPAADD400 pKa = 3.84MDD402 pKa = 4.26DD403 pKa = 5.3FSRR406 pKa = 11.84QLQNSMSGASADD418 pKa = 3.63STQAA422 pKa = 3.04

Molecular weight: 46.08 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

9245

76

4383

1320.7

147.32

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.226 ± 0.17

3.007 ± 0.429

5.343 ± 0.367

4.597 ± 0.583

4.878 ± 0.334

6.155 ± 0.567

2.001 ± 0.336

5.127 ± 0.357

5.635 ± 0.295

9.389 ± 0.639

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.326 ± 0.216

5.257 ± 0.306

4.024 ± 0.381

3.797 ± 0.712

3.797 ± 0.515

6.89 ± 0.548

6.977 ± 0.235

7.95 ± 0.718

1.136 ± 0.143

4.489 ± 0.387
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski