Amino acid dipepetide frequency for Emilia yellow vein virus-[Fz1]

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.548AlaAla: 6.548 ± 0.798
0.935AlaCys: 0.935 ± 0.778
0.935AlaAsp: 0.935 ± 0.928
0.935AlaGlu: 0.935 ± 0.747
0.935AlaPhe: 0.935 ± 0.84
0.0AlaGly: 0.0 ± 0.0
2.806AlaHis: 2.806 ± 0.775
1.871AlaIle: 1.871 ± 1.494
9.355AlaLys: 9.355 ± 2.423
3.742AlaLeu: 3.742 ± 1.038
0.935AlaMet: 0.935 ± 0.778
3.742AlaAsn: 3.742 ± 2.118
1.871AlaPro: 1.871 ± 1.494
2.806AlaGln: 2.806 ± 1.732
3.742AlaArg: 3.742 ± 2.142
1.871AlaSer: 1.871 ± 1.555
6.548AlaThr: 6.548 ± 2.198
1.871AlaVal: 1.871 ± 1.142
0.935AlaTrp: 0.935 ± 0.747
0.935AlaTyr: 0.935 ± 0.747
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.871CysCys: 1.871 ± 1.856
0.0CysAsp: 0.0 ± 0.0
0.935CysGlu: 0.935 ± 0.778
0.935CysPhe: 0.935 ± 1.025
1.871CysGly: 1.871 ± 0.888
0.935CysHis: 0.935 ± 0.84
2.806CysIle: 2.806 ± 1.582
0.935CysLys: 0.935 ± 0.778
0.0CysLeu: 0.0 ± 0.0
1.871CysMet: 1.871 ± 1.383
0.935CysAsn: 0.935 ± 0.747
2.806CysPro: 2.806 ± 1.772
1.871CysGln: 1.871 ± 1.494
0.935CysArg: 0.935 ± 0.747
2.806CysSer: 2.806 ± 1.559
0.935CysThr: 0.935 ± 0.778
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.935CysTyr: 0.935 ± 0.778
0.0CysXaa: 0.0 ± 0.0
Asp
2.806AspAla: 2.806 ± 2.242
0.0AspCys: 0.0 ± 0.0
0.935AspAsp: 0.935 ± 0.747
2.806AspGlu: 2.806 ± 1.444
1.871AspPhe: 1.871 ± 0.748
2.806AspGly: 2.806 ± 2.242
1.871AspHis: 1.871 ± 0.991
4.677AspIle: 4.677 ± 2.894
1.871AspLys: 1.871 ± 1.209
6.548AspLeu: 6.548 ± 1.596
1.871AspMet: 1.871 ± 1.209
0.935AspAsn: 0.935 ± 0.778
3.742AspPro: 3.742 ± 1.628
0.935AspGln: 0.935 ± 0.928
3.742AspArg: 3.742 ± 1.392
4.677AspSer: 4.677 ± 0.884
2.806AspThr: 2.806 ± 2.785
3.742AspVal: 3.742 ± 1.955
0.0AspTrp: 0.0 ± 0.0
0.935AspTyr: 0.935 ± 0.928
0.0AspXaa: 0.0 ± 0.0
Glu
4.677GluAla: 4.677 ± 1.333
0.0GluCys: 0.0 ± 0.0
1.871GluAsp: 1.871 ± 1.121
3.742GluGlu: 3.742 ± 1.485
0.935GluPhe: 0.935 ± 0.928
4.677GluGly: 4.677 ± 0.976
0.0GluHis: 0.0 ± 0.0
2.806GluIle: 2.806 ± 3.076
1.871GluLys: 1.871 ± 1.494
3.742GluLeu: 3.742 ± 1.741
0.935GluMet: 0.935 ± 0.907
3.742GluAsn: 3.742 ± 2.047
1.871GluPro: 1.871 ± 1.142
2.806GluGln: 2.806 ± 1.778
0.0GluArg: 0.0 ± 0.0
0.935GluSer: 0.935 ± 0.84
0.0GluThr: 0.0 ± 0.0
1.871GluVal: 1.871 ± 0.991
0.935GluTrp: 0.935 ± 0.84
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
0.935PheAla: 0.935 ± 0.747
0.935PheCys: 0.935 ± 0.778
1.871PheAsp: 1.871 ± 0.748
2.806PheGlu: 2.806 ± 0.775
0.935PhePhe: 0.935 ± 0.747
1.871PheGly: 1.871 ± 1.555
2.806PheHis: 2.806 ± 1.493
0.935PheIle: 0.935 ± 0.747
2.806PheLys: 2.806 ± 1.873
6.548PheLeu: 6.548 ± 2.381
0.935PheMet: 0.935 ± 0.778
5.613PheAsn: 5.613 ± 2.505
0.935PhePro: 0.935 ± 0.928
2.806PheGln: 2.806 ± 1.127
1.871PheArg: 1.871 ± 1.383
1.871PheSer: 1.871 ± 1.121
0.935PheThr: 0.935 ± 0.84
1.871PheVal: 1.871 ± 0.991
0.935PheTrp: 0.935 ± 0.778
0.935PheTyr: 0.935 ± 0.778
0.0PheXaa: 0.0 ± 0.0
Gly
1.871GlyAla: 1.871 ± 0.888
2.806GlyCys: 2.806 ± 0.9
2.806GlyAsp: 2.806 ± 1.278
1.871GlyGlu: 1.871 ± 1.477
1.871GlyPhe: 1.871 ± 1.209
3.742GlyGly: 3.742 ± 1.186
0.935GlyHis: 0.935 ± 0.747
2.806GlyIle: 2.806 ± 1.873
6.548GlyLys: 6.548 ± 2.672
1.871GlyLeu: 1.871 ± 1.078
0.0GlyMet: 0.0 ± 0.0
1.871GlyAsn: 1.871 ± 1.153
2.806GlyPro: 2.806 ± 1.278
3.742GlyGln: 3.742 ± 2.157
1.871GlyArg: 1.871 ± 0.888
2.806GlySer: 2.806 ± 1.411
5.613GlyThr: 5.613 ± 0.825
1.871GlyVal: 1.871 ± 0.991
0.0GlyTrp: 0.0 ± 0.0
0.935GlyTyr: 0.935 ± 0.928
0.0GlyXaa: 0.0 ± 0.0
His
0.935HisAla: 0.935 ± 0.778
2.806HisCys: 2.806 ± 1.055
0.935HisAsp: 0.935 ± 0.778
1.871HisGlu: 1.871 ± 0.888
2.806HisPhe: 2.806 ± 1.296
2.806HisGly: 2.806 ± 1.055
0.935HisHis: 0.935 ± 0.84
0.935HisIle: 0.935 ± 0.907
1.871HisLys: 1.871 ± 1.346
3.742HisLeu: 3.742 ± 1.982
0.935HisMet: 0.935 ± 0.907
3.742HisAsn: 3.742 ± 1.358
0.935HisPro: 0.935 ± 0.747
1.871HisGln: 1.871 ± 1.038
1.871HisArg: 1.871 ± 1.153
1.871HisSer: 1.871 ± 1.209
3.742HisThr: 3.742 ± 2.332
2.806HisVal: 2.806 ± 1.296
0.0HisTrp: 0.0 ± 0.0
0.935HisTyr: 0.935 ± 0.747
0.0HisXaa: 0.0 ± 0.0
Ile
2.806IleAla: 2.806 ± 1.303
1.871IleCys: 1.871 ± 0.748
2.806IleAsp: 2.806 ± 1.411
1.871IleGlu: 1.871 ± 0.991
2.806IlePhe: 2.806 ± 1.411
1.871IleGly: 1.871 ± 1.083
0.935IleHis: 0.935 ± 1.025
0.935IleIle: 0.935 ± 1.025
6.548IleLys: 6.548 ± 1.633
2.806IleLeu: 2.806 ± 0.795
1.871IleMet: 1.871 ± 1.016
3.742IleAsn: 3.742 ± 1.186
3.742IlePro: 3.742 ± 1.777
6.548IleGln: 6.548 ± 1.945
8.419IleArg: 8.419 ± 2.322
7.484IleSer: 7.484 ± 2.133
2.806IleThr: 2.806 ± 0.795
2.806IleVal: 2.806 ± 0.795
2.806IleTrp: 2.806 ± 2.026
6.548IleTyr: 6.548 ± 1.687
0.0IleXaa: 0.0 ± 0.0
Lys
8.419LysAla: 8.419 ± 2.239
1.871LysCys: 1.871 ± 0.991
3.742LysAsp: 3.742 ± 2.075
1.871LysGlu: 1.871 ± 0.748
3.742LysPhe: 3.742 ± 1.221
2.806LysGly: 2.806 ± 2.242
0.935LysHis: 0.935 ± 1.025
2.806LysIle: 2.806 ± 1.663
1.871LysLys: 1.871 ± 0.993
3.742LysLeu: 3.742 ± 1.393
0.935LysMet: 0.935 ± 0.907
5.613LysAsn: 5.613 ± 1.673
3.742LysPro: 3.742 ± 1.123
1.871LysGln: 1.871 ± 0.991
3.742LysArg: 3.742 ± 1.428
6.548LysSer: 6.548 ± 3.032
6.548LysThr: 6.548 ± 1.708
5.613LysVal: 5.613 ± 2.851
0.0LysTrp: 0.0 ± 0.0
3.742LysTyr: 3.742 ± 0.97
0.0LysXaa: 0.0 ± 0.0
Leu
0.935LeuAla: 0.935 ± 0.928
2.806LeuCys: 2.806 ± 1.493
3.742LeuAsp: 3.742 ± 2.075
1.871LeuGlu: 1.871 ± 1.281
0.935LeuPhe: 0.935 ± 0.747
5.613LeuGly: 5.613 ± 1.909
3.742LeuHis: 3.742 ± 1.358
5.613LeuIle: 5.613 ± 2.603
6.548LeuLys: 6.548 ± 1.413
4.677LeuLeu: 4.677 ± 2.25
0.0LeuMet: 0.0 ± 0.0
7.484LeuAsn: 7.484 ± 2.419
1.871LeuPro: 1.871 ± 1.083
3.742LeuGln: 3.742 ± 1.365
6.548LeuArg: 6.548 ± 1.852
5.613LeuSer: 5.613 ± 2.776
5.613LeuThr: 5.613 ± 0.792
0.935LeuVal: 0.935 ± 0.747
0.935LeuTrp: 0.935 ± 0.747
1.871LeuTyr: 1.871 ± 1.142
0.0LeuXaa: 0.0 ± 0.0
Met
1.871MetAla: 1.871 ± 1.555
0.0MetCys: 0.0 ± 0.0
5.613MetAsp: 5.613 ± 1.936
2.806MetGlu: 2.806 ± 1.675
1.871MetPhe: 1.871 ± 1.078
0.935MetGly: 0.935 ± 0.907
0.0MetHis: 0.0 ± 0.0
0.935MetIle: 0.935 ± 0.778
1.871MetLys: 1.871 ± 1.078
0.935MetLeu: 0.935 ± 0.928
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.935MetPro: 0.935 ± 0.907
0.0MetGln: 0.0 ± 0.0
0.935MetArg: 0.935 ± 0.84
1.871MetSer: 1.871 ± 1.121
0.935MetThr: 0.935 ± 0.778
0.935MetVal: 0.935 ± 0.778
1.871MetTrp: 1.871 ± 0.993
3.742MetTyr: 3.742 ± 1.681
0.0MetXaa: 0.0 ± 0.0
Asn
2.806AsnAla: 2.806 ± 0.996
1.871AsnCys: 1.871 ± 0.888
3.742AsnAsp: 3.742 ± 1.113
1.871AsnGlu: 1.871 ± 1.038
1.871AsnPhe: 1.871 ± 1.142
1.871AsnGly: 1.871 ± 1.142
3.742AsnHis: 3.742 ± 2.49
3.742AsnIle: 3.742 ± 1.955
2.806AsnLys: 2.806 ± 0.775
6.548AsnLeu: 6.548 ± 2.403
1.871AsnMet: 1.871 ± 1.444
2.806AsnAsn: 2.806 ± 0.795
2.806AsnPro: 2.806 ± 0.795
1.871AsnGln: 1.871 ± 0.991
5.613AsnArg: 5.613 ± 1.585
5.613AsnSer: 5.613 ± 1.859
1.871AsnThr: 1.871 ± 1.142
1.871AsnVal: 1.871 ± 0.991
0.0AsnTrp: 0.0 ± 0.0
3.742AsnTyr: 3.742 ± 1.038
0.0AsnXaa: 0.0 ± 0.0
Pro
0.935ProAla: 0.935 ± 1.025
2.806ProCys: 2.806 ± 1.303
3.742ProAsp: 3.742 ± 1.947
1.871ProGlu: 1.871 ± 0.888
2.806ProPhe: 2.806 ± 0.795
0.935ProGly: 0.935 ± 0.778
4.677ProHis: 4.677 ± 2.839
6.548ProIle: 6.548 ± 2.378
7.484ProLys: 7.484 ± 3.868
2.806ProLeu: 2.806 ± 1.685
4.677ProMet: 4.677 ± 1.177
2.806ProAsn: 2.806 ± 1.425
1.871ProPro: 1.871 ± 1.494
1.871ProGln: 1.871 ± 1.083
3.742ProArg: 3.742 ± 1.123
2.806ProSer: 2.806 ± 1.237
4.677ProThr: 4.677 ± 1.973
1.871ProVal: 1.871 ± 1.555
0.935ProTrp: 0.935 ± 0.747
0.935ProTyr: 0.935 ± 0.778
0.0ProXaa: 0.0 ± 0.0
Gln
2.806GlnAla: 2.806 ± 1.43
0.0GlnCys: 0.0 ± 0.0
0.935GlnAsp: 0.935 ± 0.84
0.935GlnGlu: 0.935 ± 0.778
2.806GlnPhe: 2.806 ± 1.425
2.806GlnGly: 2.806 ± 1.064
1.871GlnHis: 1.871 ± 1.083
7.484GlnIle: 7.484 ± 0.998
1.871GlnLys: 1.871 ± 1.383
0.935GlnLeu: 0.935 ± 0.84
0.935GlnMet: 0.935 ± 0.907
2.806GlnAsn: 2.806 ± 1.772
2.806GlnPro: 2.806 ± 1.685
2.806GlnGln: 2.806 ± 1.469
0.935GlnArg: 0.935 ± 0.778
3.742GlnSer: 3.742 ± 1.393
0.935GlnThr: 0.935 ± 0.84
4.677GlnVal: 4.677 ± 1.348
0.0GlnTrp: 0.0 ± 0.0
1.871GlnTyr: 1.871 ± 1.142
0.0GlnXaa: 0.0 ± 0.0
Arg
2.806ArgAla: 2.806 ± 1.43
0.935ArgCys: 0.935 ± 0.928
5.613ArgAsp: 5.613 ± 2.406
2.806ArgGlu: 2.806 ± 1.675
3.742ArgPhe: 3.742 ± 1.113
4.677ArgGly: 4.677 ± 1.426
1.871ArgHis: 1.871 ± 1.038
6.548ArgIle: 6.548 ± 1.663
4.677ArgLys: 4.677 ± 1.808
1.871ArgLeu: 1.871 ± 1.078
0.935ArgMet: 0.935 ± 0.778
0.935ArgAsn: 0.935 ± 0.84
7.484ArgPro: 7.484 ± 1.362
2.806ArgGln: 2.806 ± 1.366
7.484ArgArg: 7.484 ± 3.372
5.613ArgSer: 5.613 ± 2.68
1.871ArgThr: 1.871 ± 1.121
2.806ArgVal: 2.806 ± 1.663
0.0ArgTrp: 0.0 ± 0.0
2.806ArgTyr: 2.806 ± 1.582
0.0ArgXaa: 0.0 ± 0.0
Ser
2.806SerAla: 2.806 ± 2.242
0.0SerCys: 0.0 ± 0.0
2.806SerAsp: 2.806 ± 1.861
0.935SerGlu: 0.935 ± 0.747
2.806SerPhe: 2.806 ± 1.278
1.871SerGly: 1.871 ± 0.888
3.742SerHis: 3.742 ± 2.513
9.355SerIle: 9.355 ± 4.623
5.613SerLys: 5.613 ± 1.966
3.742SerLeu: 3.742 ± 1.358
1.871SerMet: 1.871 ± 1.078
4.677SerAsn: 4.677 ± 1.973
9.355SerPro: 9.355 ± 1.909
2.806SerGln: 2.806 ± 1.559
3.742SerArg: 3.742 ± 1.741
8.419SerSer: 8.419 ± 3.121
6.548SerThr: 6.548 ± 1.854
0.935SerVal: 0.935 ± 0.928
0.935SerTrp: 0.935 ± 0.747
2.806SerTyr: 2.806 ± 1.203
0.0SerXaa: 0.0 ± 0.0
Thr
3.742ThrAla: 3.742 ± 1.038
0.935ThrCys: 0.935 ± 0.907
2.806ThrAsp: 2.806 ± 1.383
2.806ThrGlu: 2.806 ± 1.366
1.871ThrPhe: 1.871 ± 1.281
3.742ThrGly: 3.742 ± 1.221
5.613ThrHis: 5.613 ± 2.263
2.806ThrIle: 2.806 ± 0.9
2.806ThrLys: 2.806 ± 1.278
2.806ThrLeu: 2.806 ± 0.775
1.871ThrMet: 1.871 ± 0.991
4.677ThrAsn: 4.677 ± 1.82
4.677ThrPro: 4.677 ± 1.426
0.0ThrGln: 0.0 ± 0.0
4.677ThrArg: 4.677 ± 2.997
2.806ThrSer: 2.806 ± 1.685
3.742ThrThr: 3.742 ± 2.122
3.742ThrVal: 3.742 ± 2.267
0.935ThrTrp: 0.935 ± 0.907
3.742ThrTyr: 3.742 ± 1.113
0.0ThrXaa: 0.0 ± 0.0
Val
0.935ValAla: 0.935 ± 0.778
0.935ValCys: 0.935 ± 0.778
1.871ValAsp: 1.871 ± 0.991
0.0ValGlu: 0.0 ± 0.0
3.742ValPhe: 3.742 ± 0.969
0.935ValGly: 0.935 ± 0.778
0.935ValHis: 0.935 ± 0.928
6.548ValIle: 6.548 ± 1.16
1.871ValLys: 1.871 ± 0.991
7.484ValLeu: 7.484 ± 2.46
0.935ValMet: 0.935 ± 0.778
0.0ValAsn: 0.0 ± 0.0
4.677ValPro: 4.677 ± 1.155
0.935ValGln: 0.935 ± 0.778
2.806ValArg: 2.806 ± 2.333
3.742ValSer: 3.742 ± 0.97
1.871ValThr: 1.871 ± 1.555
1.871ValVal: 1.871 ± 0.748
0.935ValTrp: 0.935 ± 0.778
2.806ValTyr: 2.806 ± 0.795
0.0ValXaa: 0.0 ± 0.0
Trp
1.871TrpAla: 1.871 ± 0.748
0.0TrpCys: 0.0 ± 0.0
0.935TrpAsp: 0.935 ± 0.928
0.935TrpGlu: 0.935 ± 1.025
0.0TrpPhe: 0.0 ± 0.0
0.935TrpGly: 0.935 ± 0.747
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.935TrpMet: 0.935 ± 0.778
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
2.806TrpArg: 2.806 ± 1.064
0.0TrpSer: 0.0 ± 0.0
1.871TrpThr: 1.871 ± 1.142
0.935TrpVal: 0.935 ± 0.747
0.0TrpTrp: 0.0 ± 0.0
0.935TrpTyr: 0.935 ± 0.747
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.806TyrAla: 2.806 ± 1.331
0.0TyrCys: 0.0 ± 0.0
1.871TyrAsp: 1.871 ± 1.038
1.871TyrGlu: 1.871 ± 1.142
1.871TyrPhe: 1.871 ± 0.991
1.871TyrGly: 1.871 ± 0.993
0.0TyrHis: 0.0 ± 0.0
1.871TyrIle: 1.871 ± 1.142
0.935TyrLys: 0.935 ± 0.84
6.548TyrLeu: 6.548 ± 1.829
2.806TyrMet: 2.806 ± 0.846
2.806TyrAsn: 2.806 ± 0.795
1.871TyrPro: 1.871 ± 1.121
1.871TyrGln: 1.871 ± 1.555
2.806TyrArg: 2.806 ± 1.331
4.677TyrSer: 4.677 ± 2.419
0.935TyrThr: 0.935 ± 0.778
2.806TyrVal: 2.806 ± 1.663
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1070 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski