Amino acid dipepetide frequency for Weeksella virosa (strain ATCC 43766 / DSM 16922 / JCM 21250 / NBRC 16016 / NCTC 11634 / CL345/78)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.991AlaAla: 3.991 ± 0.11
0.548AlaCys: 0.548 ± 0.029
3.253AlaAsp: 3.253 ± 0.078
4.446AlaGlu: 4.446 ± 0.096
3.133AlaPhe: 3.133 ± 0.073
3.796AlaGly: 3.796 ± 0.089
1.231AlaHis: 1.231 ± 0.045
5.253AlaIle: 5.253 ± 0.1
5.052AlaLys: 5.052 ± 0.109
6.049AlaLeu: 6.049 ± 0.105
1.575AlaMet: 1.575 ± 0.054
3.455AlaAsn: 3.455 ± 0.075
1.603AlaPro: 1.603 ± 0.046
2.865AlaGln: 2.865 ± 0.065
2.154AlaArg: 2.154 ± 0.058
3.551AlaSer: 3.551 ± 0.083
3.443AlaThr: 3.443 ± 0.067
3.772AlaVal: 3.772 ± 0.087
0.624AlaTrp: 0.624 ± 0.028
2.656AlaTyr: 2.656 ± 0.065
0.0AlaXaa: 0.0 ± 0.0
Cys
0.376CysAla: 0.376 ± 0.023
0.088CysCys: 0.088 ± 0.011
0.334CysAsp: 0.334 ± 0.022
0.466CysGlu: 0.466 ± 0.028
0.367CysPhe: 0.367 ± 0.025
0.59CysGly: 0.59 ± 0.03
0.142CysHis: 0.142 ± 0.017
0.53CysIle: 0.53 ± 0.027
0.406CysLys: 0.406 ± 0.024
0.662CysLeu: 0.662 ± 0.033
0.162CysMet: 0.162 ± 0.017
0.34CysAsn: 0.34 ± 0.025
0.325CysPro: 0.325 ± 0.029
0.246CysGln: 0.246 ± 0.018
0.244CysArg: 0.244 ± 0.019
0.491CysSer: 0.491 ± 0.03
0.41CysThr: 0.41 ± 0.024
0.418CysVal: 0.418 ± 0.028
0.063CysTrp: 0.063 ± 0.01
0.29CysTyr: 0.29 ± 0.019
0.0CysXaa: 0.0 ± 0.0
Asp
3.388AspAla: 3.388 ± 0.077
0.344AspCys: 0.344 ± 0.023
2.723AspAsp: 2.723 ± 0.08
4.266AspGlu: 4.266 ± 0.076
3.627AspPhe: 3.627 ± 0.072
3.323AspGly: 3.323 ± 0.09
0.957AspHis: 0.957 ± 0.038
3.891AspIle: 3.891 ± 0.081
4.121AspLys: 4.121 ± 0.074
5.308AspLeu: 5.308 ± 0.105
1.057AspMet: 1.057 ± 0.041
2.888AspAsn: 2.888 ± 0.085
1.759AspPro: 1.759 ± 0.055
2.06AspGln: 2.06 ± 0.064
2.066AspArg: 2.066 ± 0.055
2.74AspSer: 2.74 ± 0.066
2.446AspThr: 2.446 ± 0.061
3.272AspVal: 3.272 ± 0.078
0.741AspTrp: 0.741 ± 0.032
2.994AspTyr: 2.994 ± 0.068
0.0AspXaa: 0.0 ± 0.0
Glu
4.304GluAla: 4.304 ± 0.091
0.346GluCys: 0.346 ± 0.025
3.409GluAsp: 3.409 ± 0.08
5.647GluGlu: 5.647 ± 0.123
3.009GluPhe: 3.009 ± 0.069
3.545GluGly: 3.545 ± 0.076
1.135GluHis: 1.135 ± 0.046
6.064GluIle: 6.064 ± 0.092
6.888GluLys: 6.888 ± 0.118
6.353GluLeu: 6.353 ± 0.102
1.749GluMet: 1.749 ± 0.052
5.205GluAsn: 5.205 ± 0.102
1.564GluPro: 1.564 ± 0.053
2.883GluGln: 2.883 ± 0.074
2.603GluArg: 2.603 ± 0.072
3.097GluSer: 3.097 ± 0.076
3.46GluThr: 3.46 ± 0.076
4.609GluVal: 4.609 ± 0.089
0.62GluTrp: 0.62 ± 0.031
2.588GluTyr: 2.588 ± 0.065
0.0GluXaa: 0.0 ± 0.0
Phe
3.253PheAla: 3.253 ± 0.086
0.479PheCys: 0.479 ± 0.03
3.458PheAsp: 3.458 ± 0.074
2.984PheGlu: 2.984 ± 0.066
2.996PhePhe: 2.996 ± 0.096
3.698PheGly: 3.698 ± 0.087
0.963PheHis: 0.963 ± 0.044
4.093PheIle: 4.093 ± 0.098
2.491PheLys: 2.491 ± 0.073
5.07PheLeu: 5.07 ± 0.127
1.108PheMet: 1.108 ± 0.037
2.669PheAsn: 2.669 ± 0.079
1.852PhePro: 1.852 ± 0.053
1.656PheGln: 1.656 ± 0.051
2.03PheArg: 2.03 ± 0.058
4.024PheSer: 4.024 ± 0.084
3.165PheThr: 3.165 ± 0.066
3.292PheVal: 3.292 ± 0.076
0.624PheTrp: 0.624 ± 0.034
2.302PheTyr: 2.302 ± 0.07
0.0PheXaa: 0.0 ± 0.0
Gly
3.777GlyAla: 3.777 ± 0.089
0.515GlyCys: 0.515 ± 0.03
2.972GlyAsp: 2.972 ± 0.074
3.834GlyGlu: 3.834 ± 0.082
3.463GlyPhe: 3.463 ± 0.086
4.105GlyGly: 4.105 ± 0.097
1.148GlyHis: 1.148 ± 0.047
5.066GlyIle: 5.066 ± 0.099
5.307GlyLys: 5.307 ± 0.091
5.657GlyLeu: 5.657 ± 0.102
1.473GlyMet: 1.473 ± 0.055
3.382GlyAsn: 3.382 ± 0.088
1.187GlyPro: 1.187 ± 0.044
1.955GlyGln: 1.955 ± 0.051
2.198GlyArg: 2.198 ± 0.063
3.594GlySer: 3.594 ± 0.084
3.488GlyThr: 3.488 ± 0.086
4.359GlyVal: 4.359 ± 0.097
0.695GlyTrp: 0.695 ± 0.033
2.704GlyTyr: 2.704 ± 0.071
0.0GlyXaa: 0.0 ± 0.0
His
1.102HisAla: 1.102 ± 0.035
0.19HisCys: 0.19 ± 0.017
0.868HisAsp: 0.868 ± 0.037
1.054HisGlu: 1.054 ± 0.043
1.165HisPhe: 1.165 ± 0.034
1.024HisGly: 1.024 ± 0.046
0.542HisHis: 0.542 ± 0.03
1.293HisIle: 1.293 ± 0.047
1.154HisLys: 1.154 ± 0.045
2.048HisLeu: 2.048 ± 0.061
0.346HisMet: 0.346 ± 0.024
1.043HisAsn: 1.043 ± 0.04
1.012HisPro: 1.012 ± 0.043
1.03HisGln: 1.03 ± 0.043
0.801HisArg: 0.801 ± 0.036
1.117HisSer: 1.117 ± 0.035
1.006HisThr: 1.006 ± 0.038
0.963HisVal: 0.963 ± 0.04
0.202HisTrp: 0.202 ± 0.018
0.99HisTyr: 0.99 ± 0.038
0.0HisXaa: 0.0 ± 0.0
Ile
5.671IleAla: 5.671 ± 0.11
0.624IleCys: 0.624 ± 0.034
5.105IleAsp: 5.105 ± 0.079
6.232IleGlu: 6.232 ± 0.107
3.895IlePhe: 3.895 ± 0.093
5.247IleGly: 5.247 ± 0.102
1.564IleHis: 1.564 ± 0.053
6.208IleIle: 6.208 ± 0.125
5.344IleLys: 5.344 ± 0.102
7.467IleLeu: 7.467 ± 0.141
1.386IleMet: 1.386 ± 0.052
4.617IleAsn: 4.617 ± 0.091
3.229IlePro: 3.229 ± 0.079
3.132IleGln: 3.132 ± 0.064
3.004IleArg: 3.004 ± 0.071
5.22IleSer: 5.22 ± 0.099
4.356IleThr: 4.356 ± 0.085
4.783IleVal: 4.783 ± 0.092
0.662IleTrp: 0.662 ± 0.038
2.817IleTyr: 2.817 ± 0.068
0.0IleXaa: 0.0 ± 0.0
Lys
4.632LysAla: 4.632 ± 0.097
0.283LysCys: 0.283 ± 0.023
4.211LysAsp: 4.211 ± 0.092
6.418LysGlu: 6.418 ± 0.115
2.981LysPhe: 2.981 ± 0.061
4.401LysGly: 4.401 ± 0.084
1.298LysHis: 1.298 ± 0.05
6.814LysIle: 6.814 ± 0.122
7.296LysLys: 7.296 ± 0.139
6.391LysLeu: 6.391 ± 0.097
2.04LysMet: 2.04 ± 0.058
5.648LysAsn: 5.648 ± 0.091
2.28LysPro: 2.28 ± 0.059
3.045LysGln: 3.045 ± 0.066
2.838LysArg: 2.838 ± 0.069
3.916LysSer: 3.916 ± 0.079
4.713LysThr: 4.713 ± 0.091
4.704LysVal: 4.704 ± 0.085
0.711LysTrp: 0.711 ± 0.036
3.018LysTyr: 3.018 ± 0.078
0.0LysXaa: 0.0 ± 0.0
Leu
6.196LeuAla: 6.196 ± 0.094
0.659LeuCys: 0.659 ± 0.038
5.301LeuAsp: 5.301 ± 0.102
5.909LeuGlu: 5.909 ± 0.106
4.78LeuPhe: 4.78 ± 0.117
5.916LeuGly: 5.916 ± 0.105
1.811LeuHis: 1.811 ± 0.057
7.055LeuIle: 7.055 ± 0.134
7.042LeuLys: 7.042 ± 0.108
8.693LeuLeu: 8.693 ± 0.155
2.362LeuMet: 2.362 ± 0.057
5.094LeuAsn: 5.094 ± 0.085
3.883LeuPro: 3.883 ± 0.088
4.084LeuGln: 4.084 ± 0.085
3.543LeuArg: 3.543 ± 0.077
6.695LeuSer: 6.695 ± 0.099
4.966LeuThr: 4.966 ± 0.087
5.665LeuVal: 5.665 ± 0.1
0.805LeuTrp: 0.805 ± 0.034
3.478LeuTyr: 3.478 ± 0.078
0.0LeuXaa: 0.0 ± 0.0
Met
1.578MetAla: 1.578 ± 0.051
0.136MetCys: 0.136 ± 0.013
1.166MetAsp: 1.166 ± 0.039
1.249MetGlu: 1.249 ± 0.041
0.82MetPhe: 0.82 ± 0.037
1.41MetGly: 1.41 ± 0.044
0.496MetHis: 0.496 ± 0.027
1.846MetIle: 1.846 ± 0.057
2.419MetLys: 2.419 ± 0.061
1.988MetLeu: 1.988 ± 0.047
0.731MetMet: 0.731 ± 0.036
1.479MetAsn: 1.479 ± 0.043
0.799MetPro: 0.799 ± 0.035
0.97MetGln: 0.97 ± 0.041
0.981MetArg: 0.981 ± 0.033
1.352MetSer: 1.352 ± 0.047
1.096MetThr: 1.096 ± 0.041
1.398MetVal: 1.398 ± 0.045
0.157MetTrp: 0.157 ± 0.016
0.771MetTyr: 0.771 ± 0.033
0.0MetXaa: 0.0 ± 0.0
Asn
3.722AsnAla: 3.722 ± 0.081
0.365AsnCys: 0.365 ± 0.022
2.877AsnAsp: 2.877 ± 0.076
3.805AsnGlu: 3.805 ± 0.09
3.427AsnPhe: 3.427 ± 0.081
3.567AsnGly: 3.567 ± 0.091
1.269AsnHis: 1.269 ± 0.045
4.807AsnIle: 4.807 ± 0.09
4.229AsnLys: 4.229 ± 0.081
5.654AsnLeu: 5.654 ± 0.105
1.184AsnMet: 1.184 ± 0.041
3.775AsnAsn: 3.775 ± 0.094
2.864AsnPro: 2.864 ± 0.067
2.795AsnGln: 2.795 ± 0.072
2.455AsnArg: 2.455 ± 0.07
3.343AsnSer: 3.343 ± 0.077
3.124AsnThr: 3.124 ± 0.081
3.302AsnVal: 3.302 ± 0.077
0.704AsnTrp: 0.704 ± 0.03
2.738AsnTyr: 2.738 ± 0.072
0.0AsnXaa: 0.0 ± 0.0
Pro
1.811ProAla: 1.811 ± 0.058
0.199ProCys: 0.199 ± 0.017
1.751ProAsp: 1.751 ± 0.047
2.638ProGlu: 2.638 ± 0.06
1.829ProPhe: 1.829 ± 0.055
1.732ProGly: 1.732 ± 0.06
0.651ProHis: 0.651 ± 0.028
3.157ProIle: 3.157 ± 0.078
2.891ProLys: 2.891 ± 0.085
2.814ProLeu: 2.814 ± 0.076
0.835ProMet: 0.835 ± 0.033
2.349ProAsn: 2.349 ± 0.064
0.71ProPro: 0.71 ± 0.037
1.293ProGln: 1.293 ± 0.044
0.979ProArg: 0.979 ± 0.035
2.193ProSer: 2.193 ± 0.059
2.296ProThr: 2.296 ± 0.054
2.15ProVal: 2.15 ± 0.058
0.325ProTrp: 0.325 ± 0.022
1.507ProTyr: 1.507 ± 0.043
0.0ProXaa: 0.0 ± 0.0
Gln
2.524GlnAla: 2.524 ± 0.068
0.187GlnCys: 0.187 ± 0.016
1.799GlnAsp: 1.799 ± 0.053
2.94GlnGlu: 2.94 ± 0.073
1.867GlnPhe: 1.867 ± 0.048
1.957GlnGly: 1.957 ± 0.051
0.78GlnHis: 0.78 ± 0.041
3.019GlnIle: 3.019 ± 0.075
3.642GlnLys: 3.642 ± 0.092
4.186GlnLeu: 4.186 ± 0.092
0.969GlnMet: 0.969 ± 0.04
2.696GlnAsn: 2.696 ± 0.075
1.352GlnPro: 1.352 ± 0.043
2.012GlnGln: 2.012 ± 0.063
1.516GlnArg: 1.516 ± 0.052
2.183GlnSer: 2.183 ± 0.063
2.403GlnThr: 2.403 ± 0.065
2.228GlnVal: 2.228 ± 0.062
0.413GlnTrp: 0.413 ± 0.027
1.671GlnTyr: 1.671 ± 0.055
0.0GlnXaa: 0.0 ± 0.0
Arg
2.226ArgAla: 2.226 ± 0.056
0.195ArgCys: 0.195 ± 0.017
1.861ArgAsp: 1.861 ± 0.048
2.569ArgGlu: 2.569 ± 0.068
2.033ArgPhe: 2.033 ± 0.058
1.994ArgGly: 1.994 ± 0.052
0.608ArgHis: 0.608 ± 0.03
3.314ArgIle: 3.314 ± 0.073
3.268ArgLys: 3.268 ± 0.068
3.696ArgLeu: 3.696 ± 0.07
1.033ArgMet: 1.033 ± 0.042
2.368ArgAsn: 2.368 ± 0.054
1.24ArgPro: 1.24 ± 0.043
1.257ArgGln: 1.257 ± 0.04
1.43ArgArg: 1.43 ± 0.058
1.939ArgSer: 1.939 ± 0.05
1.915ArgThr: 1.915 ± 0.052
2.284ArgVal: 2.284 ± 0.061
0.425ArgTrp: 0.425 ± 0.026
1.66ArgTyr: 1.66 ± 0.056
0.0ArgXaa: 0.0 ± 0.0
Ser
3.528SerAla: 3.528 ± 0.082
0.539SerCys: 0.539 ± 0.029
3.094SerAsp: 3.094 ± 0.083
3.293SerGlu: 3.293 ± 0.07
3.51SerPhe: 3.51 ± 0.079
3.921SerGly: 3.921 ± 0.076
1.004SerHis: 1.004 ± 0.045
5.183SerIle: 5.183 ± 0.089
4.192SerLys: 4.192 ± 0.079
5.796SerLeu: 5.796 ± 0.095
1.31SerMet: 1.31 ± 0.046
3.298SerAsn: 3.298 ± 0.084
2.153SerPro: 2.153 ± 0.055
1.999SerGln: 1.999 ± 0.064
2.081SerArg: 2.081 ± 0.055
4.027SerSer: 4.027 ± 0.099
3.635SerThr: 3.635 ± 0.081
3.828SerVal: 3.828 ± 0.08
0.66SerTrp: 0.66 ± 0.039
2.716SerTyr: 2.716 ± 0.078
0.0SerXaa: 0.0 ± 0.0
Thr
3.391ThrAla: 3.391 ± 0.074
0.331ThrCys: 0.331 ± 0.021
2.997ThrAsp: 2.997 ± 0.077
3.731ThrGlu: 3.731 ± 0.078
3.018ThrPhe: 3.018 ± 0.074
3.395ThrGly: 3.395 ± 0.071
1.087ThrHis: 1.087 ± 0.043
4.753ThrIle: 4.753 ± 0.079
4.039ThrLys: 4.039 ± 0.08
5.142ThrLeu: 5.142 ± 0.08
1.034ThrMet: 1.034 ± 0.035
3.082ThrAsn: 3.082 ± 0.077
2.377ThrPro: 2.377 ± 0.063
2.268ThrGln: 2.268 ± 0.062
1.802ThrArg: 1.802 ± 0.05
3.317ThrSer: 3.317 ± 0.074
3.223ThrThr: 3.223 ± 0.084
3.382ThrVal: 3.382 ± 0.085
0.499ThrTrp: 0.499 ± 0.026
2.274ThrTyr: 2.274 ± 0.058
0.0ThrXaa: 0.0 ± 0.0
Val
3.886ValAla: 3.886 ± 0.088
0.515ValCys: 0.515 ± 0.029
3.756ValAsp: 3.756 ± 0.079
4.461ValGlu: 4.461 ± 0.084
3.274ValPhe: 3.274 ± 0.093
4.058ValGly: 4.058 ± 0.085
1.097ValHis: 1.097 ± 0.04
4.515ValIle: 4.515 ± 0.097
4.289ValLys: 4.289 ± 0.085
5.882ValLeu: 5.882 ± 0.099
1.395ValMet: 1.395 ± 0.049
3.498ValAsn: 3.498 ± 0.081
1.928ValPro: 1.928 ± 0.057
2.066ValGln: 2.066 ± 0.056
2.347ValArg: 2.347 ± 0.073
3.831ValSer: 3.831 ± 0.079
3.106ValThr: 3.106 ± 0.059
4.34ValVal: 4.34 ± 0.109
0.594ValTrp: 0.594 ± 0.026
2.669ValTyr: 2.669 ± 0.062
0.0ValXaa: 0.0 ± 0.0
Trp
0.62TrpAla: 0.62 ± 0.038
0.087TrpCys: 0.087 ± 0.011
0.57TrpAsp: 0.57 ± 0.031
0.611TrpGlu: 0.611 ± 0.026
0.555TrpPhe: 0.555 ± 0.033
0.564TrpGly: 0.564 ± 0.034
0.238TrpHis: 0.238 ± 0.021
0.793TrpIle: 0.793 ± 0.037
0.728TrpLys: 0.728 ± 0.034
0.997TrpLeu: 0.997 ± 0.041
0.328TrpMet: 0.328 ± 0.022
0.597TrpAsn: 0.597 ± 0.029
0.22TrpPro: 0.22 ± 0.02
0.481TrpGln: 0.481 ± 0.028
0.385TrpArg: 0.385 ± 0.023
0.567TrpSer: 0.567 ± 0.027
0.549TrpThr: 0.549 ± 0.033
0.668TrpVal: 0.668 ± 0.031
0.129TrpTrp: 0.129 ± 0.016
0.433TrpTyr: 0.433 ± 0.025
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.478TyrAla: 2.478 ± 0.065
0.317TyrCys: 0.317 ± 0.024
2.466TyrAsp: 2.466 ± 0.072
2.527TyrGlu: 2.527 ± 0.066
2.458TyrPhe: 2.458 ± 0.073
2.633TyrGly: 2.633 ± 0.072
0.928TyrHis: 0.928 ± 0.035
2.909TyrIle: 2.909 ± 0.071
2.84TyrLys: 2.84 ± 0.077
4.082TyrLeu: 4.082 ± 0.074
0.763TyrMet: 0.763 ± 0.03
2.522TyrAsn: 2.522 ± 0.086
1.775TyrPro: 1.775 ± 0.051
2.247TyrGln: 2.247 ± 0.068
1.856TyrArg: 1.856 ± 0.06
2.57TyrSer: 2.57 ± 0.07
2.343TyrThr: 2.343 ± 0.059
2.093TyrVal: 2.093 ± 0.057
0.467TyrTrp: 0.467 ± 0.026
1.951TyrTyr: 1.951 ± 0.072
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2045 proteins (668002 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski