Amino acid dipepetide frequency for Tinamus guttatus (White-throated tinamou)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.018AlaAla: 6.018 ± 0.059
1.368AlaCys: 1.368 ± 0.019
3.007AlaAsp: 3.007 ± 0.024
4.768AlaGlu: 4.768 ± 0.034
2.696AlaPhe: 2.696 ± 0.026
3.97AlaGly: 3.97 ± 0.03
1.397AlaHis: 1.397 ± 0.015
3.151AlaIle: 3.151 ± 0.028
3.822AlaLys: 3.822 ± 0.032
6.668AlaLeu: 6.668 ± 0.042
1.477AlaMet: 1.477 ± 0.021
2.295AlaAsn: 2.295 ± 0.021
3.028AlaPro: 3.028 ± 0.032
2.769AlaGln: 2.769 ± 0.027
3.094AlaArg: 3.094 ± 0.026
5.158AlaSer: 5.158 ± 0.037
3.39AlaThr: 3.39 ± 0.026
5.065AlaVal: 5.065 ± 0.035
0.716AlaTrp: 0.716 ± 0.014
1.641AlaTyr: 1.641 ± 0.018
0.001AlaXaa: 0.001 ± 0.0
Cys
1.281CysAla: 1.281 ± 0.017
0.649CysCys: 0.649 ± 0.013
1.048CysAsp: 1.048 ± 0.021
1.31CysGlu: 1.31 ± 0.022
0.943CysPhe: 0.943 ± 0.015
1.443CysGly: 1.443 ± 0.021
0.633CysHis: 0.633 ± 0.014
1.159CysIle: 1.159 ± 0.02
1.364CysLys: 1.364 ± 0.022
2.19CysLeu: 2.19 ± 0.028
0.464CysMet: 0.464 ± 0.012
0.905CysAsn: 0.905 ± 0.016
1.28CysPro: 1.28 ± 0.027
1.063CysGln: 1.063 ± 0.017
1.209CysArg: 1.209 ± 0.016
2.006CysSer: 2.006 ± 0.028
1.198CysThr: 1.198 ± 0.019
1.47CysVal: 1.47 ± 0.027
0.288CysTrp: 0.288 ± 0.008
0.679CysTyr: 0.679 ± 0.012
0.0CysXaa: 0.0 ± 0.0
Asp
3.041AspAla: 3.041 ± 0.028
1.08AspCys: 1.08 ± 0.02
2.818AspAsp: 2.818 ± 0.031
3.674AspGlu: 3.674 ± 0.033
2.301AspPhe: 2.301 ± 0.021
3.261AspGly: 3.261 ± 0.031
1.141AspHis: 1.141 ± 0.014
2.979AspIle: 2.979 ± 0.031
2.865AspLys: 2.865 ± 0.027
5.08AspLeu: 5.08 ± 0.031
1.162AspMet: 1.162 ± 0.014
1.941AspAsn: 1.941 ± 0.024
2.607AspPro: 2.607 ± 0.028
1.74AspGln: 1.74 ± 0.017
2.385AspArg: 2.385 ± 0.024
4.002AspSer: 4.002 ± 0.037
2.514AspThr: 2.514 ± 0.023
3.247AspVal: 3.247 ± 0.029
0.681AspTrp: 0.681 ± 0.013
1.67AspTyr: 1.67 ± 0.017
0.0AspXaa: 0.0 ± 0.0
Glu
4.734GluAla: 4.734 ± 0.041
1.305GluCys: 1.305 ± 0.031
4.543GluAsp: 4.543 ± 0.04
7.914GluGlu: 7.914 ± 0.077
2.218GluPhe: 2.218 ± 0.021
3.889GluGly: 3.889 ± 0.04
1.693GluHis: 1.693 ± 0.016
3.604GluIle: 3.604 ± 0.03
5.803GluLys: 5.803 ± 0.054
6.443GluLeu: 6.443 ± 0.05
1.759GluMet: 1.759 ± 0.02
3.432GluAsn: 3.432 ± 0.03
2.573GluPro: 2.573 ± 0.024
3.223GluGln: 3.223 ± 0.03
4.072GluArg: 4.072 ± 0.044
4.516GluSer: 4.516 ± 0.032
3.443GluThr: 3.443 ± 0.028
4.313GluVal: 4.313 ± 0.028
0.731GluTrp: 0.731 ± 0.013
1.877GluTyr: 1.877 ± 0.02
0.0GluXaa: 0.0 ± 0.0
Phe
2.221PheAla: 2.221 ± 0.022
1.016PheCys: 1.016 ± 0.015
1.867PheAsp: 1.867 ± 0.02
2.175PheGlu: 2.175 ± 0.021
1.875PhePhe: 1.875 ± 0.023
2.351PheGly: 2.351 ± 0.025
1.188PheHis: 1.188 ± 0.015
2.135PheIle: 2.135 ± 0.025
2.177PheLys: 2.177 ± 0.022
4.346PheLeu: 4.346 ± 0.04
0.806PheMet: 0.806 ± 0.014
1.569PheAsn: 1.569 ± 0.02
1.985PhePro: 1.985 ± 0.022
1.847PheGln: 1.847 ± 0.02
1.943PheArg: 1.943 ± 0.021
3.503PheSer: 3.503 ± 0.027
2.196PheThr: 2.196 ± 0.02
2.443PheVal: 2.443 ± 0.021
0.537PheTrp: 0.537 ± 0.01
1.374PheTyr: 1.374 ± 0.017
0.0PheXaa: 0.0 ± 0.0
Gly
3.62GlyAla: 3.62 ± 0.034
1.279GlyCys: 1.279 ± 0.019
2.951GlyAsp: 2.951 ± 0.03
3.662GlyGlu: 3.662 ± 0.038
2.458GlyPhe: 2.458 ± 0.028
3.852GlyGly: 3.852 ± 0.044
1.57GlyHis: 1.57 ± 0.02
3.122GlyIle: 3.122 ± 0.027
4.04GlyLys: 4.04 ± 0.041
5.251GlyLeu: 5.251 ± 0.042
1.364GlyMet: 1.364 ± 0.016
2.577GlyAsn: 2.577 ± 0.024
2.627GlyPro: 2.627 ± 0.046
2.417GlyGln: 2.417 ± 0.023
3.269GlyArg: 3.269 ± 0.034
4.932GlySer: 4.932 ± 0.034
3.399GlyThr: 3.399 ± 0.035
3.396GlyVal: 3.396 ± 0.026
0.758GlyTrp: 0.758 ± 0.014
1.896GlyTyr: 1.896 ± 0.025
0.001GlyXaa: 0.001 ± 0.0
His
1.388HisAla: 1.388 ± 0.016
0.711HisCys: 0.711 ± 0.016
0.934HisAsp: 0.934 ± 0.013
1.378HisGlu: 1.378 ± 0.013
1.108HisPhe: 1.108 ± 0.015
1.526HisGly: 1.526 ± 0.019
0.828HisHis: 0.828 ± 0.014
1.338HisIle: 1.338 ± 0.017
1.456HisLys: 1.456 ± 0.018
2.895HisLeu: 2.895 ± 0.026
0.623HisMet: 0.623 ± 0.012
0.972HisAsn: 0.972 ± 0.015
1.461HisPro: 1.461 ± 0.02
1.239HisGln: 1.239 ± 0.018
1.529HisArg: 1.529 ± 0.019
2.12HisSer: 2.12 ± 0.021
1.326HisThr: 1.326 ± 0.024
1.598HisVal: 1.598 ± 0.021
0.436HisTrp: 0.436 ± 0.009
0.859HisTyr: 0.859 ± 0.014
0.0HisXaa: 0.0 ± 0.0
Ile
3.065IleAla: 3.065 ± 0.025
1.236IleCys: 1.236 ± 0.017
2.356IleAsp: 2.356 ± 0.025
2.915IleGlu: 2.915 ± 0.027
2.309IlePhe: 2.309 ± 0.026
2.488IleGly: 2.488 ± 0.023
1.387IleHis: 1.387 ± 0.017
2.78IleIle: 2.78 ± 0.027
3.036IleLys: 3.036 ± 0.025
5.054IleLeu: 5.054 ± 0.033
1.066IleMet: 1.066 ± 0.015
2.131IleAsn: 2.131 ± 0.024
2.841IlePro: 2.841 ± 0.029
2.423IleGln: 2.423 ± 0.02
2.597IleArg: 2.597 ± 0.023
4.151IleSer: 4.151 ± 0.025
2.794IleThr: 2.794 ± 0.025
2.932IleVal: 2.932 ± 0.03
0.585IleTrp: 0.585 ± 0.011
1.654IleTyr: 1.654 ± 0.02
0.0IleXaa: 0.0 ± 0.0
Lys
4.232LysAla: 4.232 ± 0.033
1.271LysCys: 1.271 ± 0.022
3.455LysAsp: 3.455 ± 0.031
5.811LysGlu: 5.811 ± 0.057
2.054LysPhe: 2.054 ± 0.022
3.456LysGly: 3.456 ± 0.047
1.715LysHis: 1.715 ± 0.018
3.235LysIle: 3.235 ± 0.024
5.553LysLys: 5.553 ± 0.054
5.862LysLeu: 5.862 ± 0.046
1.56LysMet: 1.56 ± 0.018
2.919LysAsn: 2.919 ± 0.029
2.986LysPro: 2.986 ± 0.031
2.96LysGln: 2.96 ± 0.031
3.625LysArg: 3.625 ± 0.03
4.25LysSer: 4.25 ± 0.031
3.425LysThr: 3.425 ± 0.029
3.82LysVal: 3.82 ± 0.03
0.694LysTrp: 0.694 ± 0.012
1.931LysTyr: 1.931 ± 0.019
0.0LysXaa: 0.0 ± 0.0
Leu
6.394LeuAla: 6.394 ± 0.04
2.28LeuCys: 2.28 ± 0.023
4.985LeuAsp: 4.985 ± 0.038
7.17LeuGlu: 7.17 ± 0.054
3.713LeuPhe: 3.713 ± 0.032
5.333LeuGly: 5.333 ± 0.04
2.768LeuHis: 2.768 ± 0.024
4.284LeuIle: 4.284 ± 0.033
6.577LeuLys: 6.577 ± 0.042
10.177LeuLeu: 10.177 ± 0.079
2.085LeuMet: 2.085 ± 0.021
3.818LeuAsn: 3.818 ± 0.028
5.474LeuPro: 5.474 ± 0.032
5.531LeuGln: 5.531 ± 0.046
5.388LeuArg: 5.388 ± 0.038
7.745LeuSer: 7.745 ± 0.043
4.989LeuThr: 4.989 ± 0.033
5.541LeuVal: 5.541 ± 0.041
1.094LeuTrp: 1.094 ± 0.017
2.816LeuTyr: 2.816 ± 0.025
0.001LeuXaa: 0.001 ± 0.0
Met
1.617MetAla: 1.617 ± 0.02
0.453MetCys: 0.453 ± 0.01
1.281MetAsp: 1.281 ± 0.015
1.889MetGlu: 1.889 ± 0.019
0.844MetPhe: 0.844 ± 0.013
1.288MetGly: 1.288 ± 0.024
0.539MetHis: 0.539 ± 0.011
1.011MetIle: 1.011 ± 0.015
1.602MetLys: 1.602 ± 0.02
2.012MetLeu: 2.012 ± 0.022
0.6MetMet: 0.6 ± 0.011
0.988MetAsn: 0.988 ± 0.015
1.007MetPro: 1.007 ± 0.017
1.036MetGln: 1.036 ± 0.016
1.097MetArg: 1.097 ± 0.016
1.531MetSer: 1.531 ± 0.017
1.136MetThr: 1.136 ± 0.015
1.431MetVal: 1.431 ± 0.018
0.252MetTrp: 0.252 ± 0.007
0.661MetTyr: 0.661 ± 0.011
0.0MetXaa: 0.0 ± 0.0
Asn
2.342AsnAla: 2.342 ± 0.02
0.968AsnCys: 0.968 ± 0.018
1.718AsnAsp: 1.718 ± 0.023
2.572AsnGlu: 2.572 ± 0.026
1.741AsnPhe: 1.741 ± 0.021
2.786AsnGly: 2.786 ± 0.032
0.976AsnHis: 0.976 ± 0.013
2.48AsnIle: 2.48 ± 0.026
2.6AsnLys: 2.6 ± 0.027
4.17AsnLeu: 4.17 ± 0.033
0.994AsnMet: 0.994 ± 0.015
1.821AsnAsn: 1.821 ± 0.024
2.274AsnPro: 2.274 ± 0.024
1.655AsnGln: 1.655 ± 0.02
2.096AsnArg: 2.096 ± 0.018
3.306AsnSer: 3.306 ± 0.029
2.168AsnThr: 2.168 ± 0.024
2.506AsnVal: 2.506 ± 0.022
0.514AsnTrp: 0.514 ± 0.011
1.331AsnTyr: 1.331 ± 0.016
0.001AsnXaa: 0.001 ± 0.0
Pro
3.754ProAla: 3.754 ± 0.038
1.066ProCys: 1.066 ± 0.021
2.579ProAsp: 2.579 ± 0.024
3.839ProGlu: 3.839 ± 0.033
1.904ProPhe: 1.904 ± 0.021
3.583ProGly: 3.583 ± 0.068
1.261ProHis: 1.261 ± 0.018
1.939ProIle: 1.939 ± 0.023
2.741ProLys: 2.741 ± 0.032
4.598ProLeu: 4.598 ± 0.033
0.899ProMet: 0.899 ± 0.014
1.842ProAsn: 1.842 ± 0.019
4.009ProPro: 4.009 ± 0.06
2.275ProGln: 2.275 ± 0.026
2.649ProArg: 2.649 ± 0.029
4.851ProSer: 4.851 ± 0.042
2.504ProThr: 2.504 ± 0.026
3.665ProVal: 3.665 ± 0.028
0.623ProTrp: 0.623 ± 0.011
1.461ProTyr: 1.461 ± 0.019
0.001ProXaa: 0.001 ± 0.0
Gln
3.046GlnAla: 3.046 ± 0.032
0.976GlnCys: 0.976 ± 0.017
2.162GlnAsp: 2.162 ± 0.02
3.646GlnGlu: 3.646 ± 0.034
1.55GlnPhe: 1.55 ± 0.017
2.435GlnGly: 2.435 ± 0.027
1.266GlnHis: 1.266 ± 0.017
2.208GlnIle: 2.208 ± 0.02
3.213GlnLys: 3.213 ± 0.029
4.517GlnLeu: 4.517 ± 0.039
1.095GlnMet: 1.095 ± 0.015
1.986GlnAsn: 1.986 ± 0.019
2.221GlnPro: 2.221 ± 0.03
2.913GlnGln: 2.913 ± 0.054
2.648GlnArg: 2.648 ± 0.024
3.054GlnSer: 3.054 ± 0.031
2.259GlnThr: 2.259 ± 0.023
2.673GlnVal: 2.673 ± 0.029
0.523GlnTrp: 0.523 ± 0.011
1.344GlnTyr: 1.344 ± 0.016
0.0GlnXaa: 0.0 ± 0.0
Arg
3.296ArgAla: 3.296 ± 0.026
1.13ArgCys: 1.13 ± 0.02
2.664ArgAsp: 2.664 ± 0.028
3.943ArgGlu: 3.943 ± 0.035
1.914ArgPhe: 1.914 ± 0.02
2.904ArgGly: 2.904 ± 0.034
1.45ArgHis: 1.45 ± 0.017
2.617ArgIle: 2.617 ± 0.024
4.164ArgLys: 4.164 ± 0.044
5.19ArgLeu: 5.19 ± 0.034
1.214ArgMet: 1.214 ± 0.015
2.373ArgAsn: 2.373 ± 0.024
2.423ArgPro: 2.423 ± 0.026
2.468ArgGln: 2.468 ± 0.026
3.777ArgArg: 3.777 ± 0.037
3.937ArgSer: 3.937 ± 0.037
2.683ArgThr: 2.683 ± 0.026
3.134ArgVal: 3.134 ± 0.026
0.621ArgTrp: 0.621 ± 0.012
1.591ArgTyr: 1.591 ± 0.02
0.0ArgXaa: 0.0 ± 0.0
Ser
5.205SerAla: 5.205 ± 0.042
1.845SerCys: 1.845 ± 0.025
3.932SerAsp: 3.932 ± 0.034
5.009SerGlu: 5.009 ± 0.037
3.137SerPhe: 3.137 ± 0.026
4.793SerGly: 4.793 ± 0.039
1.955SerHis: 1.955 ± 0.023
3.605SerIle: 3.605 ± 0.03
4.432SerLys: 4.432 ± 0.039
8.009SerLeu: 8.009 ± 0.049
1.582SerMet: 1.582 ± 0.019
2.974SerAsn: 2.974 ± 0.026
5.052SerPro: 5.052 ± 0.048
3.443SerGln: 3.443 ± 0.037
4.147SerArg: 4.147 ± 0.039
8.884SerSer: 8.884 ± 0.086
4.325SerThr: 4.325 ± 0.033
5.064SerVal: 5.064 ± 0.036
0.978SerTrp: 0.978 ± 0.015
2.252SerTyr: 2.252 ± 0.022
0.001SerXaa: 0.001 ± 0.0
Thr
3.737ThrAla: 3.737 ± 0.028
1.314ThrCys: 1.314 ± 0.027
2.685ThrAsp: 2.685 ± 0.023
3.702ThrGlu: 3.702 ± 0.031
2.17ThrPhe: 2.17 ± 0.018
3.378ThrGly: 3.378 ± 0.033
1.28ThrHis: 1.28 ± 0.024
2.548ThrIle: 2.548 ± 0.023
2.834ThrLys: 2.834 ± 0.029
5.097ThrLeu: 5.097 ± 0.034
1.11ThrMet: 1.11 ± 0.014
1.921ThrAsn: 1.921 ± 0.022
2.945ThrPro: 2.945 ± 0.035
2.076ThrGln: 2.076 ± 0.024
2.424ThrArg: 2.424 ± 0.024
4.416ThrSer: 4.416 ± 0.034
2.838ThrThr: 2.838 ± 0.032
4.063ThrVal: 4.063 ± 0.033
0.651ThrTrp: 0.651 ± 0.011
1.551ThrTyr: 1.551 ± 0.018
0.0ThrXaa: 0.0 ± 0.0
Val
4.161ValAla: 4.161 ± 0.03
1.591ValCys: 1.591 ± 0.027
3.056ValAsp: 3.056 ± 0.031
4.076ValGlu: 4.076 ± 0.029
2.709ValPhe: 2.709 ± 0.028
3.262ValGly: 3.262 ± 0.029
1.589ValHis: 1.589 ± 0.02
3.299ValIle: 3.299 ± 0.031
3.854ValLys: 3.854 ± 0.029
6.441ValLeu: 6.441 ± 0.042
1.409ValMet: 1.409 ± 0.019
2.532ValAsn: 2.532 ± 0.025
3.448ValPro: 3.448 ± 0.031
2.822ValGln: 2.822 ± 0.027
3.113ValArg: 3.113 ± 0.027
4.973ValSer: 4.973 ± 0.035
3.87ValThr: 3.87 ± 0.03
4.333ValVal: 4.333 ± 0.033
0.736ValTrp: 0.736 ± 0.014
1.901ValTyr: 1.901 ± 0.021
0.001ValXaa: 0.001 ± 0.0
Trp
0.732TrpAla: 0.732 ± 0.014
0.246TrpCys: 0.246 ± 0.008
0.679TrpAsp: 0.679 ± 0.013
0.757TrpGlu: 0.757 ± 0.012
0.467TrpPhe: 0.467 ± 0.01
0.631TrpGly: 0.631 ± 0.015
0.302TrpHis: 0.302 ± 0.008
0.651TrpIle: 0.651 ± 0.012
0.908TrpLys: 0.908 ± 0.014
1.17TrpLeu: 1.17 ± 0.017
0.316TrpMet: 0.316 ± 0.008
0.727TrpAsn: 0.727 ± 0.011
0.437TrpPro: 0.437 ± 0.01
0.519TrpGln: 0.519 ± 0.009
0.679TrpArg: 0.679 ± 0.012
0.869TrpSer: 0.869 ± 0.014
0.646TrpThr: 0.646 ± 0.013
0.699TrpVal: 0.699 ± 0.014
0.19TrpTrp: 0.19 ± 0.007
0.379TrpTyr: 0.379 ± 0.01
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.615TyrAla: 1.615 ± 0.018
0.799TyrCys: 0.799 ± 0.014
1.469TyrAsp: 1.469 ± 0.016
1.876TyrGlu: 1.876 ± 0.02
1.444TyrPhe: 1.444 ± 0.021
1.809TyrGly: 1.809 ± 0.019
0.788TyrHis: 0.788 ± 0.012
1.655TyrIle: 1.655 ± 0.019
1.774TyrLys: 1.774 ± 0.018
2.994TyrLeu: 2.994 ± 0.028
0.69TyrMet: 0.69 ± 0.012
1.295TyrAsn: 1.295 ± 0.017
1.362TyrPro: 1.362 ± 0.019
1.316TyrGln: 1.316 ± 0.018
1.751TyrArg: 1.751 ± 0.021
2.417TyrSer: 2.417 ± 0.022
1.636TyrThr: 1.636 ± 0.02
1.782TyrVal: 1.782 ± 0.021
0.395TyrTrp: 0.395 ± 0.012
1.122TyrTyr: 1.122 ± 0.018
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.001XaaAla: 0.001 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.001XaaGly: 0.001 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.001XaaLys: 0.001 ± 0.0
0.001XaaLeu: 0.001 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.001XaaPro: 0.001 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.001XaaArg: 0.001 ± 0.0
0.001XaaSer: 0.001 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.041XaaXaa: 0.041 ± 0.007
Statistics based on 13377 proteins (5354997 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski