Angiostrongylus cantonensis (Rat lungworm)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Ecdysozoa; Nematoda; Chromadorea; Strongylida; Metastrongyloidea; Angiostrongylidae; Angiostrongylus

Average proteome isoelectric point is 6.85

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 14506 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A0K0D727|A0A0K0D727_ANGCA Uncharacterized protein OS=Angiostrongylus cantonensis OX=6313 PE=4 SV=1
MM1 pKa = 7.51RR2 pKa = 11.84VEE4 pKa = 4.47SLEE7 pKa = 3.94QQEE10 pKa = 4.36VGLPYY15 pKa = 10.13ISVHH19 pKa = 7.5AEE21 pKa = 3.44ILEE24 pKa = 4.16MQSLNMLQHH33 pKa = 6.7GIVAEE38 pKa = 4.17YY39 pKa = 10.57QVVPDD44 pKa = 3.69MAEE47 pKa = 3.75SPRR50 pKa = 11.84IEE52 pKa = 5.68LIDD55 pKa = 3.77LTEE58 pKa = 5.1DD59 pKa = 5.06DD60 pKa = 4.91EE61 pKa = 5.77DD62 pKa = 4.46SSAGIQQQDD71 pKa = 3.44SQIAMPLMSLQVSSVCSSLGDD92 pKa = 3.63CSAMYY97 pKa = 10.21VVIDD101 pKa = 3.88GAFPQTDD108 pKa = 3.88FLFSRR113 pKa = 11.84AYY115 pKa = 9.15QLIWVRR121 pKa = 11.84TAILNGFDD129 pKa = 4.07DD130 pKa = 4.04

Molecular weight: 14.48 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A0K0DIT6|A0A0K0DIT6_ANGCA Maelstrom domain-containing protein OS=Angiostrongylus cantonensis OX=6313 PE=3 SV=1
MM1 pKa = 7.79CSRR4 pKa = 11.84LTRR7 pKa = 11.84YY8 pKa = 8.91EE9 pKa = 3.57IRR11 pKa = 11.84LLCEE15 pKa = 3.5NTPNLVQLPVADD27 pKa = 3.92INSLFDD33 pKa = 3.44RR34 pKa = 11.84ADD36 pKa = 3.08IEE38 pKa = 4.26RR39 pKa = 11.84TGRR42 pKa = 11.84FSVQQFIAQYY52 pKa = 9.68RR53 pKa = 11.84LQKK56 pKa = 10.25RR57 pKa = 11.84LSAEE61 pKa = 3.74VHH63 pKa = 6.61FIADD67 pKa = 3.68SFISSLNLFEE77 pKa = 6.06ALDD80 pKa = 3.95SANSGNIASHH90 pKa = 7.68DD91 pKa = 3.78LLQYY95 pKa = 8.88WNKK98 pKa = 10.37AGLRR102 pKa = 11.84INEE105 pKa = 4.73GIAVLKK111 pKa = 9.33VSCISNILVFNPVMLIRR128 pKa = 11.84KK129 pKa = 8.77RR130 pKa = 11.84RR131 pKa = 11.84LAKK134 pKa = 10.46GYY136 pKa = 7.29TLSVMEE142 pKa = 5.21SEE144 pKa = 4.72PEE146 pKa = 4.15SIFIRR151 pKa = 11.84HH152 pKa = 5.49RR153 pKa = 11.84RR154 pKa = 11.84RR155 pKa = 11.84RR156 pKa = 11.84LLKK159 pKa = 9.41RR160 pKa = 11.84KK161 pKa = 6.9EE162 pKa = 3.45RR163 pKa = 11.84RR164 pKa = 11.84MRR166 pKa = 11.84HH167 pKa = 4.39EE168 pKa = 4.98RR169 pKa = 11.84IASRR173 pKa = 11.84VHH175 pKa = 4.81MM176 pKa = 4.82

Molecular weight: 20.58 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

14486

20

14506

4143969

29

6350

285.7

32.25

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.576 ± 0.019

2.286 ± 0.019

5.358 ± 0.017

6.401 ± 0.027

4.585 ± 0.015

5.65 ± 0.023

2.482 ± 0.011

5.745 ± 0.016

5.551 ± 0.024

9.418 ± 0.027

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.602 ± 0.01

4.233 ± 0.013

4.637 ± 0.025

3.72 ± 0.017

6.215 ± 0.019

7.822 ± 0.021

5.44 ± 0.016

6.942 ± 0.018

1.178 ± 0.007

3.14 ± 0.012
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski