Ursus arctos horribilis

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Laurasiatheria; Carnivora; Caniformia; Ursi

Average proteome isoelectric point is 6.75

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 35419 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A3Q7XC85|A0A3Q7XC85_URSAR vacuolar protein sorting-associated protein 26A isoform X1 OS=Ursus arctos horribilis OX=116960 GN=VPS26A PE=3 SV=1
MM1 pKa = 7.32EE2 pKa = 5.25VIVLIPYY9 pKa = 10.0VLGLLLLPLLAVALCVRR26 pKa = 11.84CRR28 pKa = 11.84EE29 pKa = 4.18MPGSYY34 pKa = 8.87DD35 pKa = 3.14TGASDD40 pKa = 4.59SLTPSIMLKK49 pKa = 10.24RR50 pKa = 11.84PPTVVPWPSATSYY63 pKa = 11.6APVTSYY69 pKa = 11.21PPLSQPDD76 pKa = 4.23LLPIPRR82 pKa = 11.84SPQPHH87 pKa = 6.67RR88 pKa = 11.84MPSSRR93 pKa = 11.84QDD95 pKa = 2.92SDD97 pKa = 3.47GANSVASYY105 pKa = 10.42EE106 pKa = 4.16NEE108 pKa = 4.15GTSGAPGALVAGRR121 pKa = 11.84LGPGPGPADD130 pKa = 3.27RR131 pKa = 11.84CVATPEE137 pKa = 4.25PACEE141 pKa = 5.16DD142 pKa = 3.79DD143 pKa = 6.32DD144 pKa = 5.13EE145 pKa = 7.07DD146 pKa = 4.93EE147 pKa = 4.31EE148 pKa = 5.84DD149 pKa = 3.83YY150 pKa = 11.55HH151 pKa = 8.47NEE153 pKa = 4.01GYY155 pKa = 11.01LEE157 pKa = 4.22VLPDD161 pKa = 3.67STPATSTAVAPAPVPSNPGLRR182 pKa = 11.84DD183 pKa = 3.14SAFSMEE189 pKa = 4.23SGEE192 pKa = 4.92DD193 pKa = 3.63YY194 pKa = 11.71VNVAEE199 pKa = 4.65SEE201 pKa = 4.22EE202 pKa = 4.29SADD205 pKa = 3.6VSLDD209 pKa = 3.29GSRR212 pKa = 11.84EE213 pKa = 3.96YY214 pKa = 11.72VNVSQEE220 pKa = 4.44LPPMARR226 pKa = 11.84TEE228 pKa = 3.92AAILNSQKK236 pKa = 10.22VEE238 pKa = 4.2DD239 pKa = 4.43EE240 pKa = 4.21DD241 pKa = 5.59DD242 pKa = 3.99EE243 pKa = 4.77EE244 pKa = 5.11EE245 pKa = 4.32EE246 pKa = 4.72GAPDD250 pKa = 3.77YY251 pKa = 11.52EE252 pKa = 4.36NLQGLHH258 pKa = 6.14

Molecular weight: 27.42 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A3Q7TGF3|A0A3Q7TGF3_URSAR extended synaptotagmin-2 isoform X1 OS=Ursus arctos horribilis OX=116960 GN=ESYT2 PE=3 SV=1
MM1 pKa = 7.57SSHH4 pKa = 5.15KK5 pKa = 8.91TFRR8 pKa = 11.84IKK10 pKa = 10.64RR11 pKa = 11.84FLAKK15 pKa = 9.71KK16 pKa = 9.58QKK18 pKa = 8.69QNRR21 pKa = 11.84PIPQWIRR28 pKa = 11.84MKK30 pKa = 9.89TGNKK34 pKa = 8.61IRR36 pKa = 11.84YY37 pKa = 7.09NSKK40 pKa = 8.3RR41 pKa = 11.84RR42 pKa = 11.84HH43 pKa = 3.95WRR45 pKa = 11.84RR46 pKa = 11.84TKK48 pKa = 10.83LGLL51 pKa = 3.67

Molecular weight: 6.41 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

19631

15788

35419

23023345

31

34350

650.0

72.34

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.102 ± 0.014

2.143 ± 0.01

4.794 ± 0.009

7.252 ± 0.018

3.51 ± 0.01

6.516 ± 0.017

2.578 ± 0.006

4.207 ± 0.012

5.726 ± 0.016

9.903 ± 0.017

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.097 ± 0.006

3.515 ± 0.009

6.472 ± 0.024

4.884 ± 0.015

5.817 ± 0.012

8.49 ± 0.015

5.277 ± 0.012

5.995 ± 0.012

1.167 ± 0.004

2.55 ± 0.007
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski