Amino acid dipepetide frequency for Bartonella bacilliformis (strain ATCC 35685 / NCTC 12138 / KC583)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.169AlaAla: 7.169 ± 0.174
0.909AlaCys: 0.909 ± 0.052
4.231AlaAsp: 4.231 ± 0.121
4.871AlaGlu: 4.871 ± 0.122
3.566AlaPhe: 3.566 ± 0.101
5.389AlaGly: 5.389 ± 0.115
2.111AlaHis: 2.111 ± 0.088
6.455AlaIle: 6.455 ± 0.144
4.498AlaLys: 4.498 ± 0.124
9.803AlaLeu: 9.803 ± 0.162
2.287AlaMet: 2.287 ± 0.08
2.957AlaAsn: 2.957 ± 0.078
2.828AlaPro: 2.828 ± 0.085
3.732AlaGln: 3.732 ± 0.102
4.627AlaArg: 4.627 ± 0.123
4.68AlaSer: 4.68 ± 0.125
3.999AlaThr: 3.999 ± 0.109
5.446AlaVal: 5.446 ± 0.146
0.804AlaTrp: 0.804 ± 0.051
2.253AlaTyr: 2.253 ± 0.077
0.0AlaXaa: 0.0 ± 0.0
Cys
0.903CysAla: 0.903 ± 0.045
0.116CysCys: 0.116 ± 0.018
0.664CysAsp: 0.664 ± 0.048
0.614CysGlu: 0.614 ± 0.044
0.604CysPhe: 0.604 ± 0.046
0.94CysGly: 0.94 ± 0.048
0.255CysHis: 0.255 ± 0.027
0.72CysIle: 0.72 ± 0.044
0.397CysLys: 0.397 ± 0.036
0.985CysLeu: 0.985 ± 0.051
0.289CysMet: 0.289 ± 0.031
0.407CysAsn: 0.407 ± 0.029
0.431CysPro: 0.431 ± 0.038
0.365CysGln: 0.365 ± 0.029
0.457CysArg: 0.457 ± 0.035
0.735CysSer: 0.735 ± 0.044
0.533CysThr: 0.533 ± 0.037
0.78CysVal: 0.78 ± 0.052
0.126CysTrp: 0.126 ± 0.019
0.349CysTyr: 0.349 ± 0.03
0.0CysXaa: 0.0 ± 0.0
Asp
4.018AspAla: 4.018 ± 0.105
0.507AspCys: 0.507 ± 0.041
2.602AspAsp: 2.602 ± 0.095
3.54AspGlu: 3.54 ± 0.102
2.563AspPhe: 2.563 ± 0.082
3.435AspGly: 3.435 ± 0.128
1.355AspHis: 1.355 ± 0.065
4.543AspIle: 4.543 ± 0.117
2.878AspLys: 2.878 ± 0.092
5.139AspLeu: 5.139 ± 0.119
1.292AspMet: 1.292 ± 0.057
2.156AspAsn: 2.156 ± 0.079
2.358AspPro: 2.358 ± 0.085
1.888AspGln: 1.888 ± 0.075
2.6AspArg: 2.6 ± 0.086
2.689AspSer: 2.689 ± 0.087
2.463AspThr: 2.463 ± 0.08
3.729AspVal: 3.729 ± 0.104
0.717AspTrp: 0.717 ± 0.046
1.762AspTyr: 1.762 ± 0.071
0.0AspXaa: 0.0 ± 0.0
Glu
5.144GluAla: 5.144 ± 0.133
0.494GluCys: 0.494 ± 0.037
2.82GluAsp: 2.82 ± 0.08
4.097GluGlu: 4.097 ± 0.114
1.778GluPhe: 1.778 ± 0.061
4.154GluGly: 4.154 ± 0.13
1.326GluHis: 1.326 ± 0.059
5.063GluIle: 5.063 ± 0.12
5.108GluLys: 5.108 ± 0.136
4.845GluLeu: 4.845 ± 0.121
1.82GluMet: 1.82 ± 0.062
3.272GluAsn: 3.272 ± 0.098
1.759GluPro: 1.759 ± 0.074
2.571GluGln: 2.571 ± 0.094
3.8GluArg: 3.8 ± 0.112
2.894GluSer: 2.894 ± 0.084
3.49GluThr: 3.49 ± 0.092
3.395GluVal: 3.395 ± 0.099
0.67GluTrp: 0.67 ± 0.04
1.368GluTyr: 1.368 ± 0.069
0.0GluXaa: 0.0 ± 0.0
Phe
3.325PheAla: 3.325 ± 0.089
0.667PheCys: 0.667 ± 0.046
2.613PheAsp: 2.613 ± 0.089
2.442PheGlu: 2.442 ± 0.098
2.566PhePhe: 2.566 ± 0.099
3.164PheGly: 3.164 ± 0.097
1.095PheHis: 1.095 ± 0.058
3.456PheIle: 3.456 ± 0.116
1.686PheLys: 1.686 ± 0.064
4.454PheLeu: 4.454 ± 0.139
1.127PheMet: 1.127 ± 0.058
1.765PheAsn: 1.765 ± 0.072
1.67PhePro: 1.67 ± 0.069
1.502PheGln: 1.502 ± 0.056
1.964PheArg: 1.964 ± 0.069
4.112PheSer: 4.112 ± 0.103
2.048PheThr: 2.048 ± 0.078
2.941PheVal: 2.941 ± 0.095
0.567PheTrp: 0.567 ± 0.042
1.465PheTyr: 1.465 ± 0.063
0.0PheXaa: 0.0 ± 0.0
Gly
5.499GlyAla: 5.499 ± 0.156
0.796GlyCys: 0.796 ± 0.046
3.351GlyAsp: 3.351 ± 0.113
3.981GlyGlu: 3.981 ± 0.108
3.256GlyPhe: 3.256 ± 0.094
5.102GlyGly: 5.102 ± 0.172
1.717GlyHis: 1.717 ± 0.068
5.281GlyIle: 5.281 ± 0.133
4.233GlyLys: 4.233 ± 0.126
6.542GlyLeu: 6.542 ± 0.164
1.683GlyMet: 1.683 ± 0.078
2.602GlyAsn: 2.602 ± 0.086
2.103GlyPro: 2.103 ± 0.079
2.7GlyGln: 2.7 ± 0.082
3.881GlyArg: 3.881 ± 0.107
4.126GlySer: 4.126 ± 0.12
3.564GlyThr: 3.564 ± 0.107
4.606GlyVal: 4.606 ± 0.143
0.819GlyTrp: 0.819 ± 0.056
2.203GlyTyr: 2.203 ± 0.076
0.0GlyXaa: 0.0 ± 0.0
His
1.914HisAla: 1.914 ± 0.07
0.284HisCys: 0.284 ± 0.029
1.218HisAsp: 1.218 ± 0.052
1.292HisGlu: 1.292 ± 0.051
1.19HisPhe: 1.19 ± 0.057
1.578HisGly: 1.578 ± 0.066
0.785HisHis: 0.785 ± 0.05
1.917HisIle: 1.917 ± 0.081
1.137HisLys: 1.137 ± 0.056
2.392HisLeu: 2.392 ± 0.086
0.596HisMet: 0.596 ± 0.042
1.024HisAsn: 1.024 ± 0.045
1.155HisPro: 1.155 ± 0.07
0.964HisGln: 0.964 ± 0.055
1.184HisArg: 1.184 ± 0.063
1.476HisSer: 1.476 ± 0.074
1.19HisThr: 1.19 ± 0.065
1.544HisVal: 1.544 ± 0.063
0.307HisTrp: 0.307 ± 0.028
0.903HisTyr: 0.903 ± 0.054
0.0HisXaa: 0.0 ± 0.0
Ile
7.361IleAla: 7.361 ± 0.139
0.898IleCys: 0.898 ± 0.048
4.546IleAsp: 4.546 ± 0.119
4.997IleGlu: 4.997 ± 0.135
3.537IlePhe: 3.537 ± 0.108
5.617IleGly: 5.617 ± 0.147
1.799IleHis: 1.799 ± 0.063
5.966IleIle: 5.966 ± 0.156
3.787IleLys: 3.787 ± 0.104
7.568IleLeu: 7.568 ± 0.167
1.72IleMet: 1.72 ± 0.074
3.451IleAsn: 3.451 ± 0.11
3.175IlePro: 3.175 ± 0.109
2.579IleGln: 2.579 ± 0.077
3.592IleArg: 3.592 ± 0.092
5.512IleSer: 5.512 ± 0.128
4.228IleThr: 4.228 ± 0.112
5.016IleVal: 5.016 ± 0.134
0.68IleTrp: 0.68 ± 0.049
1.846IleTyr: 1.846 ± 0.074
0.0IleXaa: 0.0 ± 0.0
Lys
4.832LysAla: 4.832 ± 0.114
0.357LysCys: 0.357 ± 0.036
2.776LysAsp: 2.776 ± 0.095
3.624LysGlu: 3.624 ± 0.108
1.707LysPhe: 1.707 ± 0.062
3.624LysGly: 3.624 ± 0.113
1.087LysHis: 1.087 ± 0.055
5.076LysIle: 5.076 ± 0.123
4.711LysLys: 4.711 ± 0.103
4.934LysLeu: 4.934 ± 0.112
1.623LysMet: 1.623 ± 0.06
3.325LysAsn: 3.325 ± 0.093
2.419LysPro: 2.419 ± 0.108
2.219LysGln: 2.219 ± 0.077
3.39LysArg: 3.39 ± 0.087
3.196LysSer: 3.196 ± 0.078
3.632LysThr: 3.632 ± 0.108
3.193LysVal: 3.193 ± 0.105
0.565LysTrp: 0.565 ± 0.042
1.208LysTyr: 1.208 ± 0.057
0.0LysXaa: 0.0 ± 0.0
Leu
8.332LeuAla: 8.332 ± 0.172
1.232LeuCys: 1.232 ± 0.058
4.958LeuAsp: 4.958 ± 0.115
5.583LeuGlu: 5.583 ± 0.126
4.396LeuPhe: 4.396 ± 0.14
6.174LeuGly: 6.174 ± 0.145
2.224LeuHis: 2.224 ± 0.081
7.017LeuIle: 7.017 ± 0.167
5.835LeuLys: 5.835 ± 0.127
9.396LeuLeu: 9.396 ± 0.239
2.45LeuMet: 2.45 ± 0.07
4.204LeuAsn: 4.204 ± 0.121
4.435LeuPro: 4.435 ± 0.107
3.881LeuGln: 3.881 ± 0.111
5.281LeuArg: 5.281 ± 0.12
8.296LeuSer: 8.296 ± 0.168
5.357LeuThr: 5.357 ± 0.132
5.893LeuVal: 5.893 ± 0.112
1.032LeuTrp: 1.032 ± 0.057
2.713LeuTyr: 2.713 ± 0.092
0.0LeuXaa: 0.0 ± 0.0
Met
2.39MetAla: 2.39 ± 0.084
0.247MetCys: 0.247 ± 0.027
1.166MetAsp: 1.166 ± 0.056
1.279MetGlu: 1.279 ± 0.063
0.79MetPhe: 0.79 ± 0.043
1.668MetGly: 1.668 ± 0.081
0.53MetHis: 0.53 ± 0.038
1.922MetIle: 1.922 ± 0.074
1.602MetLys: 1.602 ± 0.074
2.384MetLeu: 2.384 ± 0.082
0.856MetMet: 0.856 ± 0.049
1.179MetAsn: 1.179 ± 0.058
1.137MetPro: 1.137 ± 0.049
1.195MetGln: 1.195 ± 0.056
1.652MetArg: 1.652 ± 0.066
1.584MetSer: 1.584 ± 0.062
1.649MetThr: 1.649 ± 0.067
1.67MetVal: 1.67 ± 0.065
0.189MetTrp: 0.189 ± 0.026
0.381MetTyr: 0.381 ± 0.028
0.0MetXaa: 0.0 ± 0.0
Asn
3.721AsnAla: 3.721 ± 0.086
0.378AsnCys: 0.378 ± 0.034
2.211AsnAsp: 2.211 ± 0.082
2.332AsnGlu: 2.332 ± 0.081
2.093AsnPhe: 2.093 ± 0.071
3.083AsnGly: 3.083 ± 0.112
1.148AsnHis: 1.148 ± 0.056
3.564AsnIle: 3.564 ± 0.1
2.337AsnLys: 2.337 ± 0.073
4.139AsnLeu: 4.139 ± 0.116
1.019AsnMet: 1.019 ± 0.05
2.114AsnAsn: 2.114 ± 0.092
2.119AsnPro: 2.119 ± 0.078
1.723AsnGln: 1.723 ± 0.071
2.138AsnArg: 2.138 ± 0.081
2.595AsnSer: 2.595 ± 0.101
2.033AsnThr: 2.033 ± 0.083
2.663AsnVal: 2.663 ± 0.089
0.554AsnTrp: 0.554 ± 0.039
1.19AsnTyr: 1.19 ± 0.06
0.0AsnXaa: 0.0 ± 0.0
Pro
2.692ProAla: 2.692 ± 0.107
0.391ProCys: 0.391 ± 0.03
2.3ProAsp: 2.3 ± 0.084
2.855ProGlu: 2.855 ± 0.115
2.046ProPhe: 2.046 ± 0.075
2.49ProGly: 2.49 ± 0.091
1.153ProHis: 1.153 ± 0.059
3.054ProIle: 3.054 ± 0.09
2.012ProLys: 2.012 ± 0.076
4.013ProLeu: 4.013 ± 0.102
0.867ProMet: 0.867 ± 0.046
1.591ProAsn: 1.591 ± 0.063
1.584ProPro: 1.584 ± 0.069
1.857ProGln: 1.857 ± 0.069
1.696ProArg: 1.696 ± 0.07
2.568ProSer: 2.568 ± 0.103
2.14ProThr: 2.14 ± 0.079
2.839ProVal: 2.839 ± 0.09
0.42ProTrp: 0.42 ± 0.031
1.166ProTyr: 1.166 ± 0.054
0.0ProXaa: 0.0 ± 0.0
Gln
3.438GlnAla: 3.438 ± 0.105
0.389GlnCys: 0.389 ± 0.034
1.778GlnAsp: 1.778 ± 0.072
2.608GlnGlu: 2.608 ± 0.084
1.523GlnPhe: 1.523 ± 0.06
2.395GlnGly: 2.395 ± 0.097
0.867GlnHis: 0.867 ± 0.053
3.104GlnIle: 3.104 ± 0.101
3.146GlnLys: 3.146 ± 0.103
3.603GlnLeu: 3.603 ± 0.102
1.174GlnMet: 1.174 ± 0.058
2.069GlnAsn: 2.069 ± 0.075
1.429GlnPro: 1.429 ± 0.108
1.82GlnGln: 1.82 ± 0.089
2.363GlnArg: 2.363 ± 0.076
2.421GlnSer: 2.421 ± 0.079
2.413GlnThr: 2.413 ± 0.087
2.248GlnVal: 2.248 ± 0.082
0.504GlnTrp: 0.504 ± 0.041
0.998GlnTyr: 0.998 ± 0.052
0.0GlnXaa: 0.0 ± 0.0
Arg
4.081ArgAla: 4.081 ± 0.1
0.499ArgCys: 0.499 ± 0.036
2.92ArgAsp: 2.92 ± 0.08
3.254ArgGlu: 3.254 ± 0.084
2.634ArgPhe: 2.634 ± 0.087
3.217ArgGly: 3.217 ± 0.098
1.255ArgHis: 1.255 ± 0.072
4.139ArgIle: 4.139 ± 0.131
2.831ArgLys: 2.831 ± 0.097
5.704ArgLeu: 5.704 ± 0.134
1.366ArgMet: 1.366 ± 0.066
2.109ArgAsn: 2.109 ± 0.071
1.993ArgPro: 1.993 ± 0.081
2.206ArgGln: 2.206 ± 0.072
3.023ArgArg: 3.023 ± 0.103
3.288ArgSer: 3.288 ± 0.1
2.55ArgThr: 2.55 ± 0.083
3.671ArgVal: 3.671 ± 0.116
0.575ArgTrp: 0.575 ± 0.038
1.865ArgTyr: 1.865 ± 0.071
0.0ArgXaa: 0.0 ± 0.0
Ser
5.076SerAla: 5.076 ± 0.104
0.678SerCys: 0.678 ± 0.045
3.577SerAsp: 3.577 ± 0.099
3.571SerGlu: 3.571 ± 0.116
3.432SerPhe: 3.432 ± 0.097
4.903SerGly: 4.903 ± 0.135
1.568SerHis: 1.568 ± 0.06
4.59SerIle: 4.59 ± 0.129
3.217SerLys: 3.217 ± 0.097
7.014SerLeu: 7.014 ± 0.159
1.502SerMet: 1.502 ± 0.061
2.566SerAsn: 2.566 ± 0.085
2.413SerPro: 2.413 ± 0.09
2.595SerGln: 2.595 ± 0.092
3.136SerArg: 3.136 ± 0.109
4.871SerSer: 4.871 ± 0.144
3.293SerThr: 3.293 ± 0.104
4.359SerVal: 4.359 ± 0.124
0.798SerTrp: 0.798 ± 0.047
2.103SerTyr: 2.103 ± 0.08
0.0SerXaa: 0.0 ± 0.0
Thr
4.388ThrAla: 4.388 ± 0.125
0.481ThrCys: 0.481 ± 0.034
2.658ThrAsp: 2.658 ± 0.086
2.82ThrGlu: 2.82 ± 0.098
2.13ThrPhe: 2.13 ± 0.084
4.055ThrGly: 4.055 ± 0.115
1.368ThrHis: 1.368 ± 0.066
4.322ThrIle: 4.322 ± 0.113
2.563ThrLys: 2.563 ± 0.078
5.814ThrLeu: 5.814 ± 0.14
1.237ThrMet: 1.237 ± 0.059
2.09ThrAsn: 2.09 ± 0.081
2.571ThrPro: 2.571 ± 0.076
2.308ThrGln: 2.308 ± 0.086
2.518ThrArg: 2.518 ± 0.091
3.283ThrSer: 3.283 ± 0.106
2.983ThrThr: 2.983 ± 0.102
3.776ThrVal: 3.776 ± 0.091
0.473ThrTrp: 0.473 ± 0.034
1.35ThrTyr: 1.35 ± 0.062
0.0ThrXaa: 0.0 ± 0.0
Val
5.383ValAla: 5.383 ± 0.149
0.754ValCys: 0.754 ± 0.045
3.537ValAsp: 3.537 ± 0.096
4.152ValGlu: 4.152 ± 0.106
2.92ValPhe: 2.92 ± 0.103
4.275ValGly: 4.275 ± 0.106
1.342ValHis: 1.342 ± 0.056
5.016ValIle: 5.016 ± 0.125
3.508ValLys: 3.508 ± 0.099
6.001ValLeu: 6.001 ± 0.16
1.694ValMet: 1.694 ± 0.071
2.555ValAsn: 2.555 ± 0.098
2.508ValPro: 2.508 ± 0.085
2.437ValGln: 2.437 ± 0.077
3.556ValArg: 3.556 ± 0.103
4.732ValSer: 4.732 ± 0.117
3.658ValThr: 3.658 ± 0.105
4.509ValVal: 4.509 ± 0.121
0.586ValTrp: 0.586 ± 0.045
1.555ValTyr: 1.555 ± 0.055
0.0ValXaa: 0.0 ± 0.0
Trp
0.725TrpAla: 0.725 ± 0.047
0.129TrpCys: 0.129 ± 0.02
0.496TrpAsp: 0.496 ± 0.039
0.431TrpGlu: 0.431 ± 0.034
0.538TrpPhe: 0.538 ± 0.04
0.68TrpGly: 0.68 ± 0.046
0.318TrpHis: 0.318 ± 0.031
0.814TrpIle: 0.814 ± 0.045
0.667TrpLys: 0.667 ± 0.045
1.305TrpLeu: 1.305 ± 0.065
0.255TrpMet: 0.255 ± 0.027
0.502TrpAsn: 0.502 ± 0.039
0.444TrpPro: 0.444 ± 0.039
0.502TrpGln: 0.502 ± 0.034
0.738TrpArg: 0.738 ± 0.045
0.638TrpSer: 0.638 ± 0.041
0.483TrpThr: 0.483 ± 0.034
0.699TrpVal: 0.699 ± 0.05
0.2TrpTrp: 0.2 ± 0.025
0.373TrpTyr: 0.373 ± 0.033
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.224TyrAla: 2.224 ± 0.069
0.467TyrCys: 0.467 ± 0.044
1.812TyrAsp: 1.812 ± 0.075
1.526TyrGlu: 1.526 ± 0.053
1.36TyrPhe: 1.36 ± 0.062
2.103TyrGly: 2.103 ± 0.079
0.748TyrHis: 0.748 ± 0.041
1.859TyrIle: 1.859 ± 0.079
1.345TyrLys: 1.345 ± 0.065
2.655TyrLeu: 2.655 ± 0.087
0.612TyrMet: 0.612 ± 0.041
1.213TyrAsn: 1.213 ± 0.059
1.2TyrPro: 1.2 ± 0.054
1.247TyrGln: 1.247 ± 0.059
1.581TyrArg: 1.581 ± 0.076
1.568TyrSer: 1.568 ± 0.067
1.481TyrThr: 1.481 ± 0.066
1.699TyrVal: 1.699 ± 0.073
0.349TyrTrp: 0.349 ± 0.031
0.885TyrTyr: 0.885 ± 0.061
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1255 proteins (380800 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski