Amino acid dipepetide frequency for Prevotella baroniae F0067

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.148AlaAla: 7.148 ± 0.124	1.127AlaCys: 1.127 ± 0.037	5.24AlaAsp: 5.24 ± 0.089	4.689AlaGlu: 4.689 ± 0.09	3.603AlaPhe: 3.603 ± 0.061	5.767AlaGly: 5.767 ± 0.087	1.543AlaHis: 1.543 ± 0.038	4.427AlaIle: 4.427 ± 0.078	4.493AlaLys: 4.493 ± 0.087	7.238AlaLeu: 7.238 ± 0.095	2.309AlaMet: 2.309 ± 0.058	3.38AlaAsn: 3.38 ± 0.072	2.512AlaPro: 2.512 ± 0.057	3.13AlaGln: 3.13 ± 0.062	4.206AlaArg: 4.206 ± 0.077	4.375AlaSer: 4.375 ± 0.065	4.538AlaThr: 4.538 ± 0.074	5.489AlaVal: 5.489 ± 0.094	0.989AlaTrp: 0.989 ± 0.039	3.141AlaTyr: 3.141 ± 0.055	0.0AlaXaa: 0.0 ± 0.0
Cys	0.856CysAla: 0.856 ± 0.035	0.181CysCys: 0.181 ± 0.014	0.691CysAsp: 0.691 ± 0.029	0.628CysGlu: 0.628 ± 0.026	0.577CysPhe: 0.577 ± 0.029	1.03CysGly: 1.03 ± 0.035	0.372CysHis: 0.372 ± 0.024	0.638CysIle: 0.638 ± 0.025	0.656CysLys: 0.656 ± 0.028	1.079CysLeu: 1.079 ± 0.034	0.345CysMet: 0.345 ± 0.022	0.552CysAsn: 0.552 ± 0.023	0.495CysPro: 0.495 ± 0.023	0.374CysGln: 0.374 ± 0.021	0.803CysArg: 0.803 ± 0.034	0.72CysSer: 0.72 ± 0.029	0.61CysThr: 0.61 ± 0.025	0.866CysVal: 0.866 ± 0.03	0.162CysTrp: 0.162 ± 0.015	0.533CysTyr: 0.533 ± 0.027	0.0CysXaa: 0.0 ± 0.0
Asp	4.372AspAla: 4.372 ± 0.078	0.727AspCys: 0.727 ± 0.031	3.316AspAsp: 3.316 ± 0.062	3.86AspGlu: 3.86 ± 0.068	3.121AspPhe: 3.121 ± 0.068	4.866AspGly: 4.866 ± 0.089	1.078AspHis: 1.078 ± 0.037	3.956AspIle: 3.956 ± 0.069	3.744AspLys: 3.744 ± 0.068	4.771AspLeu: 4.771 ± 0.072	1.813AspMet: 1.813 ± 0.044	2.928AspAsn: 2.928 ± 0.065	1.956AspPro: 1.956 ± 0.052	1.372AspGln: 1.372 ± 0.043	3.229AspArg: 3.229 ± 0.066	3.039AspSer: 3.039 ± 0.06	2.778AspThr: 2.778 ± 0.066	3.98AspVal: 3.98 ± 0.069	0.904AspTrp: 0.904 ± 0.034	2.956AspTyr: 2.956 ± 0.058	0.0AspXaa: 0.0 ± 0.0
Glu	5.253GluAla: 5.253 ± 0.084	0.574GluCys: 0.574 ± 0.026	2.974GluAsp: 2.974 ± 0.06	4.009GluGlu: 4.009 ± 0.091	2.027GluPhe: 2.027 ± 0.051	3.898GluGly: 3.898 ± 0.073	1.215GluHis: 1.215 ± 0.036	3.562GluIle: 3.562 ± 0.071	4.041GluLys: 4.041 ± 0.08	5.342GluLeu: 5.342 ± 0.094	1.77GluMet: 1.77 ± 0.046	2.894GluAsn: 2.894 ± 0.061	1.746GluPro: 1.746 ± 0.042	2.506GluGln: 2.506 ± 0.055	3.456GluArg: 3.456 ± 0.065	2.784GluSer: 2.784 ± 0.055	3.074GluThr: 3.074 ± 0.059	3.79GluVal: 3.79 ± 0.066	0.724GluTrp: 0.724 ± 0.032	2.257GluTyr: 2.257 ± 0.057	0.0GluXaa: 0.0 ± 0.0
Phe	3.281PheAla: 3.281 ± 0.064	0.668PheCys: 0.668 ± 0.027	2.93PheAsp: 2.93 ± 0.061	2.299PheGlu: 2.299 ± 0.053	2.043PhePhe: 2.043 ± 0.048	3.463PheGly: 3.463 ± 0.069	1.043PheHis: 1.043 ± 0.038	2.55PheIle: 2.55 ± 0.055	2.406PheLys: 2.406 ± 0.051	3.614PheLeu: 3.614 ± 0.077	1.374PheMet: 1.374 ± 0.042	2.324PheAsn: 2.324 ± 0.054	1.57PhePro: 1.57 ± 0.039	1.278PheGln: 1.278 ± 0.032	2.257PheArg: 2.257 ± 0.056	3.102PheSer: 3.102 ± 0.065	2.761PheThr: 2.761 ± 0.064	2.983PheVal: 2.983 ± 0.057	0.545PheTrp: 0.545 ± 0.027	1.844PheTyr: 1.844 ± 0.052	0.0PheXaa: 0.0 ± 0.0
Gly	4.789GlyAla: 4.789 ± 0.087	1.039GlyCys: 1.039 ± 0.036	3.917GlyAsp: 3.917 ± 0.077	3.914GlyGlu: 3.914 ± 0.069	3.267GlyPhe: 3.267 ± 0.06	5.263GlyGly: 5.263 ± 0.08	1.572GlyHis: 1.572 ± 0.041	4.274GlyIle: 4.274 ± 0.086	5.089GlyLys: 5.089 ± 0.075	6.373GlyLeu: 6.373 ± 0.093	2.247GlyMet: 2.247 ± 0.053	3.568GlyAsn: 3.568 ± 0.073	1.472GlyPro: 1.472 ± 0.048	2.583GlyGln: 2.583 ± 0.067	4.284GlyArg: 4.284 ± 0.078	4.227GlySer: 4.227 ± 0.07	4.33GlyThr: 4.33 ± 0.081	5.203GlyVal: 5.203 ± 0.082	1.174GlyTrp: 1.174 ± 0.042	3.301GlyTyr: 3.301 ± 0.077	0.0GlyXaa: 0.0 ± 0.0
His	1.67HisAla: 1.67 ± 0.046	0.335HisCys: 0.335 ± 0.021	1.289HisAsp: 1.289 ± 0.042	1.11HisGlu: 1.11 ± 0.037	1.104HisPhe: 1.104 ± 0.036	1.533HisGly: 1.533 ± 0.039	0.661HisHis: 0.661 ± 0.028	1.374HisIle: 1.374 ± 0.04	1.067HisLys: 1.067 ± 0.038	1.907HisLeu: 1.907 ± 0.046	0.419HisMet: 0.419 ± 0.021	0.89HisAsn: 0.89 ± 0.035	1.146HisPro: 1.146 ± 0.037	0.769HisGln: 0.769 ± 0.031	1.195HisArg: 1.195 ± 0.044	1.147HisSer: 1.147 ± 0.034	1.132HisThr: 1.132 ± 0.034	1.509HisVal: 1.509 ± 0.046	0.275HisTrp: 0.275 ± 0.017	1.007HisTyr: 1.007 ± 0.035	0.0HisXaa: 0.0 ± 0.0
Ile	4.755IleAla: 4.755 ± 0.088	0.75IleCys: 0.75 ± 0.029	4.076IleAsp: 4.076 ± 0.076	3.492IleGlu: 3.492 ± 0.068	2.162IlePhe: 2.162 ± 0.059	4.137IleGly: 4.137 ± 0.077	1.289IleHis: 1.289 ± 0.039	3.311IleIle: 3.311 ± 0.073	3.263IleLys: 3.263 ± 0.066	4.761IleLeu: 4.761 ± 0.086	1.389IleMet: 1.389 ± 0.042	2.745IleAsn: 2.745 ± 0.063	2.57IlePro: 2.57 ± 0.058	1.847IleGln: 1.847 ± 0.045	3.17IleArg: 3.17 ± 0.07	3.66IleSer: 3.66 ± 0.064	3.178IleThr: 3.178 ± 0.064	4.015IleVal: 4.015 ± 0.07	0.516IleTrp: 0.516 ± 0.024	2.277IleTyr: 2.277 ± 0.054	0.0IleXaa: 0.0 ± 0.0
Lys	5.36LysAla: 5.36 ± 0.086	0.506LysCys: 0.506 ± 0.023	3.829LysAsp: 3.829 ± 0.068	4.32LysGlu: 4.32 ± 0.087	2.062LysPhe: 2.062 ± 0.046	4.328LysGly: 4.328 ± 0.084	1.17LysHis: 1.17 ± 0.039	3.323LysIle: 3.323 ± 0.071	4.05LysLys: 4.05 ± 0.083	5.194LysLeu: 5.194 ± 0.07	1.985LysMet: 1.985 ± 0.048	2.965LysAsn: 2.965 ± 0.057	2.293LysPro: 2.293 ± 0.056	2.394LysGln: 2.394 ± 0.049	3.291LysArg: 3.291 ± 0.058	3.243LysSer: 3.243 ± 0.062	3.621LysThr: 3.621 ± 0.065	4.109LysVal: 4.109 ± 0.066	0.744LysTrp: 0.744 ± 0.029	2.508LysTyr: 2.508 ± 0.06	0.0LysXaa: 0.0 ± 0.0
Leu	7.118LeuAla: 7.118 ± 0.103	1.327LeuCys: 1.327 ± 0.045	5.018LeuAsp: 5.018 ± 0.084	4.56LeuGlu: 4.56 ± 0.085	4.125LeuPhe: 4.125 ± 0.085	6.074LeuGly: 6.074 ± 0.101	2.094LeuHis: 2.094 ± 0.05	4.312LeuIle: 4.312 ± 0.081	5.763LeuLys: 5.763 ± 0.083	9.012LeuLeu: 9.012 ± 0.163	2.473LeuMet: 2.473 ± 0.053	4.295LeuAsn: 4.295 ± 0.084	4.149LeuPro: 4.149 ± 0.061	3.504LeuGln: 3.504 ± 0.064	5.292LeuArg: 5.292 ± 0.093	6.497LeuSer: 6.497 ± 0.088	5.602LeuThr: 5.602 ± 0.083	5.414LeuVal: 5.414 ± 0.077	1.078LeuTrp: 1.078 ± 0.04	3.491LeuTyr: 3.491 ± 0.071	0.0LeuXaa: 0.0 ± 0.0
Met	2.665MetAla: 2.665 ± 0.061	0.23MetCys: 0.23 ± 0.017	1.575MetAsp: 1.575 ± 0.043	1.779MetGlu: 1.779 ± 0.045	1.03MetPhe: 1.03 ± 0.037	2.081MetGly: 2.081 ± 0.049	0.474MetHis: 0.474 ± 0.023	1.351MetIle: 1.351 ± 0.043	2.528MetLys: 2.528 ± 0.051	2.586MetLeu: 2.586 ± 0.058	0.941MetMet: 0.941 ± 0.035	1.492MetAsn: 1.492 ± 0.037	1.261MetPro: 1.261 ± 0.033	1.094MetGln: 1.094 ± 0.039	1.561MetArg: 1.561 ± 0.045	1.582MetSer: 1.582 ± 0.047	1.805MetThr: 1.805 ± 0.042	1.734MetVal: 1.734 ± 0.05	0.251MetTrp: 0.251 ± 0.018	0.776MetTyr: 0.776 ± 0.027	0.0MetXaa: 0.0 ± 0.0
Asn	3.924AsnAla: 3.924 ± 0.076	0.497AsnCys: 0.497 ± 0.025	2.686AsnAsp: 2.686 ± 0.06	2.492AsnGlu: 2.492 ± 0.055	2.048AsnPhe: 2.048 ± 0.051	3.71AsnGly: 3.71 ± 0.076	1.084AsnHis: 1.084 ± 0.038	3.149AsnIle: 3.149 ± 0.065	2.693AsnLys: 2.693 ± 0.058	4.159AsnLeu: 4.159 ± 0.082	1.288AsnMet: 1.288 ± 0.042	2.22AsnAsn: 2.22 ± 0.064	2.422AsnPro: 2.422 ± 0.054	1.537AsnGln: 1.537 ± 0.043	2.675AsnArg: 2.675 ± 0.058	2.415AsnSer: 2.415 ± 0.061	2.568AsnThr: 2.568 ± 0.053	3.344AsnVal: 3.344 ± 0.056	0.611AsnTrp: 0.611 ± 0.031	2.205AsnTyr: 2.205 ± 0.059	0.0AsnXaa: 0.0 ± 0.0
Pro	3.058ProAla: 3.058 ± 0.067	0.381ProCys: 0.381 ± 0.024	2.498ProAsp: 2.498 ± 0.052	2.822ProGlu: 2.822 ± 0.055	1.908ProPhe: 1.908 ± 0.052	2.447ProGly: 2.447 ± 0.054	0.771ProHis: 0.771 ± 0.034	2.023ProIle: 2.023 ± 0.047	2.054ProLys: 2.054 ± 0.048	3.363ProLeu: 3.363 ± 0.06	1.045ProMet: 1.045 ± 0.033	1.654ProAsn: 1.654 ± 0.047	0.816ProPro: 0.816 ± 0.032	1.532ProGln: 1.532 ± 0.043	1.597ProArg: 1.597 ± 0.042	2.325ProSer: 2.325 ± 0.056	2.284ProThr: 2.284 ± 0.049	2.893ProVal: 2.893 ± 0.057	0.449ProTrp: 0.449 ± 0.023	1.709ProTyr: 1.709 ± 0.045	0.0ProXaa: 0.0 ± 0.0
Gln	3.031GlnAla: 3.031 ± 0.061	0.358GlnCys: 0.358 ± 0.018	1.599GlnAsp: 1.599 ± 0.04	2.134GlnGlu: 2.134 ± 0.047	1.344GlnPhe: 1.344 ± 0.032	2.37GlnGly: 2.37 ± 0.061	0.743GlnHis: 0.743 ± 0.029	2.016GlnIle: 2.016 ± 0.051	2.226GlnLys: 2.226 ± 0.052	3.789GlnLeu: 3.789 ± 0.082	1.098GlnMet: 1.098 ± 0.034	1.699GlnAsn: 1.699 ± 0.052	1.548GlnPro: 1.548 ± 0.042	1.715GlnGln: 1.715 ± 0.053	2.08GlnArg: 2.08 ± 0.054	1.987GlnSer: 1.987 ± 0.047	2.269GlnThr: 2.269 ± 0.049	2.341GlnVal: 2.341 ± 0.052	0.524GlnTrp: 0.524 ± 0.025	1.437GlnTyr: 1.437 ± 0.042	0.0GlnXaa: 0.0 ± 0.0
Arg	3.403ArgAla: 3.403 ± 0.065	0.563ArgCys: 0.563 ± 0.025	2.627ArgAsp: 2.627 ± 0.053	3.022ArgGlu: 3.022 ± 0.062	2.652ArgPhe: 2.652 ± 0.057	3.098ArgGly: 3.098 ± 0.06	1.634ArgHis: 1.634 ± 0.051	3.227ArgIle: 3.227 ± 0.063	3.598ArgLys: 3.598 ± 0.067	5.907ArgLeu: 5.907 ± 0.088	1.876ArgMet: 1.876 ± 0.053	2.688ArgAsn: 2.688 ± 0.061	2.04ArgPro: 2.04 ± 0.052	2.872ArgGln: 2.872 ± 0.067	3.734ArgArg: 3.734 ± 0.08	2.777ArgSer: 2.777 ± 0.061	2.668ArgThr: 2.668 ± 0.059	3.284ArgVal: 3.284 ± 0.069	0.831ArgTrp: 0.831 ± 0.03	2.537ArgTyr: 2.537 ± 0.058	0.0ArgXaa: 0.0 ± 0.0
Ser	4.301SerAla: 4.301 ± 0.07	0.775SerCys: 0.775 ± 0.033	3.208SerAsp: 3.208 ± 0.064	3.036SerGlu: 3.036 ± 0.068	3.029SerPhe: 3.029 ± 0.064	4.414SerGly: 4.414 ± 0.075	1.363SerHis: 1.363 ± 0.039	3.487SerIle: 3.487 ± 0.068	3.179SerLys: 3.179 ± 0.064	5.795SerLeu: 5.795 ± 0.101	1.557SerMet: 1.557 ± 0.038	2.513SerAsn: 2.513 ± 0.055	2.294SerPro: 2.294 ± 0.052	1.896SerGln: 1.896 ± 0.049	3.0SerArg: 3.0 ± 0.06	3.511SerSer: 3.511 ± 0.072	3.259SerThr: 3.259 ± 0.063	4.183SerVal: 4.183 ± 0.075	0.813SerTrp: 0.813 ± 0.034	2.772SerTyr: 2.772 ± 0.072	0.0SerXaa: 0.0 ± 0.0
Thr	4.828ThrAla: 4.828 ± 0.082	0.573ThrCys: 0.573 ± 0.029	3.635ThrAsp: 3.635 ± 0.07	2.908ThrGlu: 2.908 ± 0.06	2.862ThrPhe: 2.862 ± 0.063	4.464ThrGly: 4.464 ± 0.065	1.065ThrHis: 1.065 ± 0.035	3.557ThrIle: 3.557 ± 0.07	2.817ThrLys: 2.817 ± 0.06	5.641ThrLeu: 5.641 ± 0.089	1.466ThrMet: 1.466 ± 0.043	2.352ThrAsn: 2.352 ± 0.056	2.764ThrPro: 2.764 ± 0.054	1.77ThrGln: 1.77 ± 0.044	2.591ThrArg: 2.591 ± 0.057	3.227ThrSer: 3.227 ± 0.059	3.573ThrThr: 3.573 ± 0.08	4.011ThrVal: 4.011 ± 0.078	0.691ThrTrp: 0.691 ± 0.031	2.42ThrTyr: 2.42 ± 0.057	0.0ThrXaa: 0.0 ± 0.0
Val	5.509ValAla: 5.509 ± 0.08	0.926ValCys: 0.926 ± 0.034	4.344ValAsp: 4.344 ± 0.062	4.023ValGlu: 4.023 ± 0.07	2.83ValPhe: 2.83 ± 0.061	4.814ValGly: 4.814 ± 0.086	1.084ValHis: 1.084 ± 0.036	3.788ValIle: 3.788 ± 0.067	4.363ValLys: 4.363 ± 0.086	5.554ValLeu: 5.554 ± 0.086	1.885ValMet: 1.885 ± 0.047	3.395ValAsn: 3.395 ± 0.062	2.58ValPro: 2.58 ± 0.061	1.916ValGln: 1.916 ± 0.041	3.401ValArg: 3.401 ± 0.069	4.494ValSer: 4.494 ± 0.077	3.978ValThr: 3.978 ± 0.09	5.441ValVal: 5.441 ± 0.092	0.783ValTrp: 0.783 ± 0.032	2.765ValTyr: 2.765 ± 0.052	0.0ValXaa: 0.0 ± 0.0
Trp	0.859TrpAla: 0.859 ± 0.035	0.149TrpCys: 0.149 ± 0.015	0.666TrpAsp: 0.666 ± 0.025	0.652TrpGlu: 0.652 ± 0.033	0.53TrpPhe: 0.53 ± 0.024	0.97TrpGly: 0.97 ± 0.033	0.291TrpHis: 0.291 ± 0.019	0.704TrpIle: 0.704 ± 0.031	0.885TrpLys: 0.885 ± 0.032	1.329TrpLeu: 1.329 ± 0.042	0.414TrpMet: 0.414 ± 0.021	0.845TrpAsn: 0.845 ± 0.033	0.353TrpPro: 0.353 ± 0.019	0.62TrpGln: 0.62 ± 0.028	0.707TrpArg: 0.707 ± 0.032	0.71TrpSer: 0.71 ± 0.028	0.733TrpThr: 0.733 ± 0.034	0.706TrpVal: 0.706 ± 0.03	0.205TrpTrp: 0.205 ± 0.017	0.479TrpTyr: 0.479 ± 0.025	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.165TyrAla: 3.165 ± 0.064	0.481TyrCys: 0.481 ± 0.021	2.649TyrAsp: 2.649 ± 0.057	2.147TyrGlu: 2.147 ± 0.051	2.013TyrPhe: 2.013 ± 0.052	3.162TyrGly: 3.162 ± 0.066	0.995TyrHis: 0.995 ± 0.031	2.336TyrIle: 2.336 ± 0.056	2.377TyrLys: 2.377 ± 0.059	3.781TyrLeu: 3.781 ± 0.07	1.102TyrMet: 1.102 ± 0.031	2.327TyrAsn: 2.327 ± 0.061	1.639TyrPro: 1.639 ± 0.049	1.601TyrGln: 1.601 ± 0.048	2.508TyrArg: 2.508 ± 0.059	2.561TyrSer: 2.561 ± 0.063	2.455TyrThr: 2.455 ± 0.063	2.579TyrVal: 2.579 ± 0.059	0.537TyrTrp: 0.537 ± 0.023	2.004TyrTyr: 2.004 ± 0.058	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2480 proteins (896784 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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