Amino acid dipepetide frequency for Wuhan Mosquito Virus 8

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.703AlaAla: 8.703 ± 4.225
1.451AlaCys: 1.451 ± 0.602
3.481AlaAsp: 3.481 ± 1.579
3.191AlaGlu: 3.191 ± 0.645
2.901AlaPhe: 2.901 ± 1.275
3.771AlaGly: 3.771 ± 1.498
1.741AlaHis: 1.741 ± 0.612
3.481AlaIle: 3.481 ± 1.143
2.031AlaLys: 2.031 ± 0.855
6.382AlaLeu: 6.382 ± 1.672
3.771AlaMet: 3.771 ± 1.305
2.321AlaAsn: 2.321 ± 0.946
3.191AlaPro: 3.191 ± 1.302
1.741AlaGln: 1.741 ± 0.108
2.901AlaArg: 2.901 ± 1.073
4.932AlaSer: 4.932 ± 0.649
3.771AlaThr: 3.771 ± 0.382
3.771AlaVal: 3.771 ± 1.498
0.87AlaTrp: 0.87 ± 0.497
4.352AlaTyr: 4.352 ± 0.175
0.0AlaXaa: 0.0 ± 0.0
Cys
1.741CysAla: 1.741 ± 1.245
0.29CysCys: 0.29 ± 0.406
1.451CysAsp: 1.451 ± 0.058
1.451CysGlu: 1.451 ± 0.829
0.29CysPhe: 0.29 ± 0.166
0.87CysGly: 0.87 ± 1.285
0.29CysHis: 0.29 ± 0.166
0.87CysIle: 0.87 ± 0.389
2.031CysLys: 2.031 ± 0.76
3.191CysLeu: 3.191 ± 0.645
0.87CysMet: 0.87 ± 0.308
1.451CysAsn: 1.451 ± 0.476
1.16CysPro: 1.16 ± 0.669
0.87CysGln: 0.87 ± 0.389
1.451CysArg: 1.451 ± 0.476
1.16CysSer: 1.16 ± 0.669
0.87CysThr: 0.87 ± 0.308
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
2.901CysTyr: 2.901 ± 0.625
0.0CysXaa: 0.0 ± 0.0
Asp
3.771AspAla: 3.771 ± 0.767
2.031AspCys: 2.031 ± 1.444
2.321AspAsp: 2.321 ± 0.447
4.352AspGlu: 4.352 ± 0.441
3.191AspPhe: 3.191 ± 0.608
2.901AspGly: 2.901 ± 0.428
0.87AspHis: 0.87 ± 0.497
3.191AspIle: 3.191 ± 0.605
2.901AspLys: 2.901 ± 0.116
6.382AspLeu: 6.382 ± 1.911
1.451AspMet: 1.451 ± 0.476
1.451AspAsn: 1.451 ± 0.578
2.901AspPro: 2.901 ± 1.957
1.451AspGln: 1.451 ± 0.621
2.321AspArg: 2.321 ± 0.755
3.771AspSer: 3.771 ± 1.791
4.642AspThr: 4.642 ± 1.035
3.481AspVal: 3.481 ± 0.629
0.58AspTrp: 0.58 ± 0.334
2.611AspTyr: 2.611 ± 0.372
0.0AspXaa: 0.0 ± 0.0
Glu
5.222GluAla: 5.222 ± 1.35
1.16GluCys: 1.16 ± 0.224
4.352GluAsp: 4.352 ± 2.014
4.932GluGlu: 4.932 ± 2.579
2.031GluPhe: 2.031 ± 0.274
4.352GluGly: 4.352 ± 0.382
1.451GluHis: 1.451 ± 1.08
3.481GluIle: 3.481 ± 1.555
2.901GluLys: 2.901 ± 1.029
5.222GluLeu: 5.222 ± 1.706
1.16GluMet: 1.16 ± 0.397
3.191GluAsn: 3.191 ± 2.017
2.031GluPro: 2.031 ± 0.355
2.321GluGln: 2.321 ± 0.793
2.611GluArg: 2.611 ± 0.925
4.352GluSer: 4.352 ± 1.01
3.771GluThr: 3.771 ± 1.946
4.062GluVal: 4.062 ± 1.225
0.58GluTrp: 0.58 ± 0.331
1.741GluTyr: 1.741 ± 0.108
0.0GluXaa: 0.0 ± 0.0
Phe
0.87PheAla: 0.87 ± 0.308
1.741PheCys: 1.741 ± 0.994
1.741PheAsp: 1.741 ± 0.648
2.031PheGlu: 2.031 ± 0.76
0.58PhePhe: 0.58 ± 0.331
2.901PheGly: 2.901 ± 0.642
0.29PheHis: 0.29 ± 0.166
2.321PheIle: 2.321 ± 0.73
1.16PheLys: 1.16 ± 0.224
3.481PheLeu: 3.481 ± 1.224
0.0PheMet: 0.0 ± 0.0
1.741PheAsn: 1.741 ± 0.994
2.611PhePro: 2.611 ± 1.158
0.58PheGln: 0.58 ± 0.811
2.901PheArg: 2.901 ± 1.275
3.481PheSer: 3.481 ± 1.095
1.741PheThr: 1.741 ± 1.02
3.191PheVal: 3.191 ± 1.015
0.87PheTrp: 0.87 ± 0.905
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
2.321GlyAla: 2.321 ± 1.26
1.741GlyCys: 1.741 ± 0.465
2.611GlyAsp: 2.611 ± 0.8
2.901GlyGlu: 2.901 ± 1.957
4.062GlyPhe: 4.062 ± 0.548
2.901GlyGly: 2.901 ± 1.633
2.031GlyHis: 2.031 ± 0.803
1.741GlyIle: 1.741 ± 0.654
0.87GlyLys: 0.87 ± 0.389
4.642GlyLeu: 4.642 ± 1.106
2.611GlyMet: 2.611 ± 0.686
2.031GlyAsn: 2.031 ± 0.613
1.451GlyPro: 1.451 ± 0.602
2.031GlyGln: 2.031 ± 0.274
1.16GlyArg: 1.16 ± 0.721
3.481GlySer: 3.481 ± 1.434
2.031GlyThr: 2.031 ± 0.354
3.771GlyVal: 3.771 ± 0.505
0.29GlyTrp: 0.29 ± 0.428
2.321GlyTyr: 2.321 ± 0.299
0.0GlyXaa: 0.0 ± 0.0
His
1.451HisAla: 1.451 ± 0.476
0.87HisCys: 0.87 ± 0.389
0.87HisAsp: 0.87 ± 0.324
0.58HisGlu: 0.58 ± 0.334
0.87HisPhe: 0.87 ± 0.497
0.87HisGly: 0.87 ± 0.308
0.58HisHis: 0.58 ± 0.331
1.741HisIle: 1.741 ± 0.994
2.611HisLys: 2.611 ± 0.33
2.611HisLeu: 2.611 ± 0.686
0.87HisMet: 0.87 ± 0.497
1.16HisAsn: 1.16 ± 0.397
0.87HisPro: 0.87 ± 0.308
0.87HisGln: 0.87 ± 0.324
0.29HisArg: 0.29 ± 0.428
2.031HisSer: 2.031 ± 0.949
1.451HisThr: 1.451 ± 0.829
1.741HisVal: 1.741 ± 1.003
0.0HisTrp: 0.0 ± 0.0
1.16HisTyr: 1.16 ± 0.663
0.0HisXaa: 0.0 ± 0.0
Ile
3.191IleAla: 3.191 ± 0.053
1.16IleCys: 1.16 ± 0.224
2.901IleAsp: 2.901 ± 0.771
3.191IleGlu: 3.191 ± 1.02
2.031IlePhe: 2.031 ± 1.374
1.16IleGly: 1.16 ± 0.721
1.16IleHis: 1.16 ± 0.669
4.352IleIle: 4.352 ± 1.108
3.481IleLys: 3.481 ± 0.217
4.932IleLeu: 4.932 ± 1.931
3.191IleMet: 3.191 ± 1.779
2.031IleAsn: 2.031 ± 0.355
4.352IlePro: 4.352 ± 1.208
2.031IleGln: 2.031 ± 0.949
4.932IleArg: 4.932 ± 1.592
4.932IleSer: 4.932 ± 2.373
6.382IleThr: 6.382 ± 0.67
3.771IleVal: 3.771 ± 1.37
1.451IleTrp: 1.451 ± 0.058
2.321IleTyr: 2.321 ± 0.73
0.0IleXaa: 0.0 ± 0.0
Lys
2.031LysAla: 2.031 ± 0.613
0.29LysCys: 0.29 ± 0.166
3.771LysAsp: 3.771 ± 0.92
4.642LysGlu: 4.642 ± 0.647
3.191LysPhe: 3.191 ± 1.015
1.741LysGly: 1.741 ± 0.465
1.451LysHis: 1.451 ± 0.63
5.512LysIle: 5.512 ± 1.869
3.481LysLys: 3.481 ± 0.966
8.123LysLeu: 8.123 ± 1.206
1.16LysMet: 1.16 ± 0.365
4.062LysAsn: 4.062 ± 0.354
1.16LysPro: 1.16 ± 0.669
1.16LysGln: 1.16 ± 0.721
1.16LysArg: 1.16 ± 0.224
3.481LysSer: 3.481 ± 0.39
4.352LysThr: 4.352 ± 0.441
3.191LysVal: 3.191 ± 1.084
0.29LysTrp: 0.29 ± 0.166
1.741LysTyr: 1.741 ± 0.612
0.0LysXaa: 0.0 ± 0.0
Leu
5.222LeuAla: 5.222 ± 0.353
2.031LeuCys: 2.031 ± 0.76
5.802LeuAsp: 5.802 ± 1.169
6.092LeuGlu: 6.092 ± 1.276
2.611LeuPhe: 2.611 ± 0.372
3.771LeuGly: 3.771 ± 1.498
1.451LeuHis: 1.451 ± 0.829
4.642LeuIle: 4.642 ± 1.599
5.802LeuLys: 5.802 ± 0.412
8.123LeuLeu: 8.123 ± 1.208
3.191LeuMet: 3.191 ± 0.558
2.611LeuAsn: 2.611 ± 0.925
4.352LeuPro: 4.352 ± 1.174
4.062LeuGln: 4.062 ± 0.788
7.253LeuArg: 7.253 ± 1.314
8.123LeuSer: 8.123 ± 1.096
5.222LeuThr: 5.222 ± 1.35
7.543LeuVal: 7.543 ± 0.765
0.58LeuTrp: 0.58 ± 0.331
5.222LeuTyr: 5.222 ± 1.542
0.0LeuXaa: 0.0 ± 0.0
Met
2.901MetAla: 2.901 ± 1.073
1.451MetCys: 1.451 ± 0.476
2.031MetAsp: 2.031 ± 0.354
2.611MetGlu: 2.611 ± 1.115
0.87MetPhe: 0.87 ± 1.285
0.87MetGly: 0.87 ± 0.75
0.58MetHis: 0.58 ± 0.334
1.741MetIle: 1.741 ± 0.973
2.321MetLys: 2.321 ± 0.44
2.031MetLeu: 2.031 ± 0.803
1.16MetMet: 1.16 ± 0.393
1.741MetAsn: 1.741 ± 0.654
1.451MetPro: 1.451 ± 0.829
0.58MetGln: 0.58 ± 0.327
1.451MetArg: 1.451 ± 0.63
1.741MetSer: 1.741 ± 0.612
1.451MetThr: 1.451 ± 0.058
1.451MetVal: 1.451 ± 0.515
0.58MetTrp: 0.58 ± 0.334
2.611MetTyr: 2.611 ± 0.281
0.0MetXaa: 0.0 ± 0.0
Asn
3.481AsnAla: 3.481 ± 0.754
0.87AsnCys: 0.87 ± 0.497
2.031AsnAsp: 2.031 ± 0.354
2.321AsnGlu: 2.321 ± 0.447
1.16AsnPhe: 1.16 ± 0.365
0.87AsnGly: 0.87 ± 0.389
1.16AsnHis: 1.16 ± 0.663
2.611AsnIle: 2.611 ± 1.072
3.771AsnLys: 3.771 ± 0.693
3.481AsnLeu: 3.481 ± 0.689
1.451AsnMet: 1.451 ± 0.058
2.321AsnAsn: 2.321 ± 0.946
2.031AsnPro: 2.031 ± 0.354
2.031AsnGln: 2.031 ± 0.95
1.16AsnArg: 1.16 ± 0.655
2.901AsnSer: 2.901 ± 0.625
1.451AsnThr: 1.451 ± 0.476
2.901AsnVal: 2.901 ± 1.156
0.87AsnTrp: 0.87 ± 0.497
2.611AsnTyr: 2.611 ± 1.115
0.0AsnXaa: 0.0 ± 0.0
Pro
3.191ProAla: 3.191 ± 1.968
0.0ProCys: 0.0 ± 0.0
2.611ProAsp: 2.611 ± 1.296
3.191ProGlu: 3.191 ± 0.645
1.451ProPhe: 1.451 ± 0.058
2.031ProGly: 2.031 ± 1.116
1.451ProHis: 1.451 ± 0.058
3.191ProIle: 3.191 ± 0.608
2.321ProLys: 2.321 ± 0.73
4.352ProLeu: 4.352 ± 0.99
0.87ProMet: 0.87 ± 1.217
0.87ProAsn: 0.87 ± 0.497
1.741ProPro: 1.741 ± 0.654
0.87ProGln: 0.87 ± 0.308
1.741ProArg: 1.741 ± 0.778
4.062ProSer: 4.062 ± 0.709
3.191ProThr: 3.191 ± 1.015
3.191ProVal: 3.191 ± 0.605
0.58ProTrp: 0.58 ± 0.327
2.321ProTyr: 2.321 ± 0.299
0.0ProXaa: 0.0 ± 0.0
Gln
2.901GlnAla: 2.901 ± 0.642
0.58GlnCys: 0.58 ± 0.857
2.031GlnAsp: 2.031 ± 0.803
1.451GlnGlu: 1.451 ± 0.476
0.58GlnPhe: 0.58 ± 0.331
2.031GlnGly: 2.031 ± 0.855
1.16GlnHis: 1.16 ± 0.397
3.771GlnIle: 3.771 ± 0.334
1.741GlnLys: 1.741 ± 0.45
3.191GlnLeu: 3.191 ± 0.558
0.58GlnMet: 0.58 ± 0.334
1.16GlnAsn: 1.16 ± 0.365
1.16GlnPro: 1.16 ± 0.224
1.16GlnGln: 1.16 ± 0.224
1.741GlnArg: 1.741 ± 0.648
1.741GlnSer: 1.741 ± 1.245
1.451GlnThr: 1.451 ± 0.602
2.901GlnVal: 2.901 ± 1.002
0.0GlnTrp: 0.0 ± 0.0
2.321GlnTyr: 2.321 ± 0.922
0.0GlnXaa: 0.0 ± 0.0
Arg
2.901ArgAla: 2.901 ± 0.476
0.58ArgCys: 0.58 ± 0.334
3.481ArgAsp: 3.481 ± 0.382
4.352ArgGlu: 4.352 ± 1.108
1.741ArgPhe: 1.741 ± 0.654
1.451ArgGly: 1.451 ± 0.476
1.451ArgHis: 1.451 ± 1.08
2.611ArgIle: 2.611 ± 0.681
3.481ArgLys: 3.481 ± 1.103
4.932ArgLeu: 4.932 ± 0.429
2.031ArgMet: 2.031 ± 0.855
2.321ArgAsn: 2.321 ± 0.914
1.741ArgPro: 1.741 ± 0.648
2.031ArgGln: 2.031 ± 0.95
3.771ArgArg: 3.771 ± 2.797
4.062ArgSer: 4.062 ± 0.788
2.901ArgThr: 2.901 ± 2.176
3.481ArgVal: 3.481 ± 1.295
0.58ArgTrp: 0.58 ± 0.331
2.901ArgTyr: 2.901 ± 1.637
0.0ArgXaa: 0.0 ± 0.0
Ser
4.642SerAla: 4.642 ± 0.879
2.031SerCys: 2.031 ± 0.949
6.092SerAsp: 6.092 ± 1.898
4.932SerGlu: 4.932 ± 0.161
1.451SerPhe: 1.451 ± 0.621
6.092SerGly: 6.092 ± 0.596
1.16SerHis: 1.16 ± 0.365
4.642SerIle: 4.642 ± 0.984
4.642SerLys: 4.642 ± 1.828
8.413SerLeu: 8.413 ± 2.904
2.031SerMet: 2.031 ± 0.803
1.741SerAsn: 1.741 ± 1.003
2.611SerPro: 2.611 ± 0.605
2.901SerGln: 2.901 ± 1.023
3.771SerArg: 3.771 ± 0.382
5.802SerSer: 5.802 ± 0.747
3.771SerThr: 3.771 ± 0.906
4.642SerVal: 4.642 ± 1.334
1.16SerTrp: 1.16 ± 0.669
3.191SerTyr: 3.191 ± 0.937
0.0SerXaa: 0.0 ± 0.0
Thr
5.222ThrAla: 5.222 ± 1.949
1.741ThrCys: 1.741 ± 0.973
2.901ThrAsp: 2.901 ± 1.156
3.771ThrGlu: 3.771 ± 0.334
1.451ThrPhe: 1.451 ± 0.829
3.191ThrGly: 3.191 ± 0.506
1.741ThrHis: 1.741 ± 0.994
4.932ThrIle: 4.932 ± 1.058
3.191ThrLys: 3.191 ± 0.836
4.352ThrLeu: 4.352 ± 0.382
1.741ThrMet: 1.741 ± 0.108
2.031ThrAsn: 2.031 ± 0.655
2.901ThrPro: 2.901 ± 0.116
2.321ThrGln: 2.321 ± 1.871
4.642ThrArg: 4.642 ± 0.547
5.512ThrSer: 5.512 ± 2.39
2.611ThrThr: 2.611 ± 1.35
3.771ThrVal: 3.771 ± 0.693
1.451ThrTrp: 1.451 ± 1.08
2.611ThrTyr: 2.611 ± 1.28
0.0ThrXaa: 0.0 ± 0.0
Val
5.512ValAla: 5.512 ± 2.796
1.741ValCys: 1.741 ± 0.108
3.481ValAsp: 3.481 ± 0.217
3.771ValGlu: 3.771 ± 0.92
1.451ValPhe: 1.451 ± 0.476
2.031ValGly: 2.031 ± 0.274
1.741ValHis: 1.741 ± 1.003
3.481ValIle: 3.481 ± 1.422
4.062ValLys: 4.062 ± 0.709
4.932ValLeu: 4.932 ± 0.677
2.031ValMet: 2.031 ± 0.655
3.191ValAsn: 3.191 ± 0.608
3.481ValPro: 3.481 ± 1.307
1.741ValGln: 1.741 ± 0.617
4.352ValArg: 4.352 ± 0.382
5.802ValSer: 5.802 ± 1.379
5.802ValThr: 5.802 ± 1.379
7.253ValVal: 7.253 ± 1.345
0.29ValTrp: 0.29 ± 0.166
3.771ValTyr: 3.771 ± 0.92
0.0ValXaa: 0.0 ± 0.0
Trp
0.87TrpAla: 0.87 ± 0.324
0.29TrpCys: 0.29 ± 0.166
0.29TrpAsp: 0.29 ± 0.428
0.29TrpGlu: 0.29 ± 0.428
1.16TrpPhe: 1.16 ± 0.669
0.29TrpGly: 0.29 ± 0.428
0.0TrpHis: 0.0 ± 0.0
0.87TrpIle: 0.87 ± 0.308
0.87TrpLys: 0.87 ± 0.308
0.58TrpLeu: 0.58 ± 0.334
0.29TrpMet: 0.29 ± 0.406
1.451TrpAsn: 1.451 ± 0.476
0.29TrpPro: 0.29 ± 0.166
0.0TrpGln: 0.0 ± 0.0
0.29TrpArg: 0.29 ± 0.166
1.16TrpSer: 1.16 ± 0.365
0.58TrpThr: 0.58 ± 0.327
1.16TrpVal: 1.16 ± 0.663
0.0TrpTrp: 0.0 ± 0.0
1.451TrpTyr: 1.451 ± 0.602
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.611TyrAla: 2.611 ± 0.33
1.16TyrCys: 1.16 ± 0.663
2.321TyrAsp: 2.321 ± 0.73
0.87TyrGlu: 0.87 ± 0.308
1.16TyrPhe: 1.16 ± 0.224
2.901TyrGly: 2.901 ± 0.428
1.741TyrHis: 1.741 ± 0.465
3.771TyrIle: 3.771 ± 1.717
2.321TyrLys: 2.321 ± 0.299
4.352TyrLeu: 4.352 ± 0.714
0.87TyrMet: 0.87 ± 0.226
2.611TyrAsn: 2.611 ± 0.33
1.741TyrPro: 1.741 ± 0.465
2.901TyrGln: 2.901 ± 0.649
2.901TyrArg: 2.901 ± 0.476
3.191TyrSer: 3.191 ± 0.506
4.642TyrThr: 4.642 ± 1.557
4.642TyrVal: 4.642 ± 0.506
1.16TyrTrp: 1.16 ± 0.224
2.611TyrTyr: 2.611 ± 0.605
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (3448 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski