Amino acid dipepetide frequency for Beihai picorna-like virus 114

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.33AlaAla: 2.33 ± 1.262
0.666AlaCys: 0.666 ± 0.171
3.995AlaAsp: 3.995 ± 1.556
5.992AlaGlu: 5.992 ± 0.474
2.996AlaPhe: 2.996 ± 0.56
3.662AlaGly: 3.662 ± 1.205
2.33AlaHis: 2.33 ± 0.332
3.995AlaIle: 3.995 ± 1.024
3.995AlaLys: 3.995 ± 0.57
4.66AlaLeu: 4.66 ± 0.132
1.332AlaMet: 1.332 ± 0.341
1.997AlaAsn: 1.997 ± 1.575
2.663AlaPro: 2.663 ± 1.214
1.664AlaGln: 1.664 ± 0.161
4.66AlaArg: 4.66 ± 0.399
3.995AlaSer: 3.995 ± 1.024
4.328AlaThr: 4.328 ± 0.313
2.996AlaVal: 2.996 ± 0.502
0.666AlaTrp: 0.666 ± 0.361
2.996AlaTyr: 2.996 ± 0.502
0.0AlaXaa: 0.0 ± 0.0
Cys
0.666CysAla: 0.666 ± 0.171
0.333CysCys: 0.333 ± 0.351
0.333CysAsp: 0.333 ± 0.18
0.333CysGlu: 0.333 ± 0.351
1.332CysPhe: 1.332 ± 0.721
1.997CysGly: 1.997 ± 0.512
0.999CysHis: 0.999 ± 0.01
0.333CysIle: 0.333 ± 0.18
2.33CysLys: 2.33 ± 0.332
1.332CysLeu: 1.332 ± 0.19
0.333CysMet: 0.333 ± 0.18
0.666CysAsn: 0.666 ± 0.171
1.664CysPro: 1.664 ± 0.692
0.666CysGln: 0.666 ± 0.361
0.999CysArg: 0.999 ± 0.541
2.996CysSer: 2.996 ± 0.56
1.332CysThr: 1.332 ± 0.19
0.999CysVal: 0.999 ± 0.541
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.328AspAla: 4.328 ± 0.313
1.997AspCys: 1.997 ± 1.082
1.997AspAsp: 1.997 ± 0.551
2.663AspGlu: 2.663 ± 0.38
1.997AspPhe: 1.997 ± 0.551
3.995AspGly: 3.995 ± 1.101
2.33AspHis: 2.33 ± 0.332
4.993AspIle: 4.993 ± 1.546
1.997AspLys: 1.997 ± 0.551
4.993AspLeu: 4.993 ± 2.077
1.997AspMet: 1.997 ± 0.551
2.663AspAsn: 2.663 ± 0.683
2.33AspPro: 2.33 ± 0.2
1.664AspGln: 1.664 ± 0.161
1.997AspArg: 1.997 ± 1.044
2.33AspSer: 2.33 ± 0.332
2.663AspThr: 2.663 ± 0.911
3.329AspVal: 3.329 ± 0.322
0.999AspTrp: 0.999 ± 0.541
1.332AspTyr: 1.332 ± 0.19
0.0AspXaa: 0.0 ± 0.0
Glu
2.663GluAla: 2.663 ± 1.746
0.999GluCys: 0.999 ± 0.522
2.663GluAsp: 2.663 ± 0.38
10.32GluGlu: 10.32 ± 2.402
1.332GluPhe: 1.332 ± 0.341
2.663GluGly: 2.663 ± 0.683
0.999GluHis: 0.999 ± 0.01
4.328GluIle: 4.328 ± 0.313
2.33GluLys: 2.33 ± 0.731
5.659GluLeu: 5.659 ± 0.123
1.997GluMet: 1.997 ± 0.019
3.662GluAsn: 3.662 ± 0.39
2.663GluPro: 2.663 ± 1.443
3.662GluGln: 3.662 ± 0.142
1.332GluArg: 1.332 ± 0.721
6.991GluSer: 6.991 ± 0.599
4.328GluThr: 4.328 ± 0.75
3.329GluVal: 3.329 ± 0.209
0.666GluTrp: 0.666 ± 0.702
2.663GluTyr: 2.663 ± 0.911
0.0GluXaa: 0.0 ± 0.0
Phe
2.996PheAla: 2.996 ± 0.029
0.999PheCys: 0.999 ± 0.01
1.997PheAsp: 1.997 ± 0.551
2.996PheGlu: 2.996 ± 0.029
2.996PhePhe: 2.996 ± 0.56
3.329PheGly: 3.329 ± 1.385
0.666PheHis: 0.666 ± 0.171
1.664PheIle: 1.664 ± 0.692
1.997PheLys: 1.997 ± 0.551
4.328PheLeu: 4.328 ± 0.75
1.664PheMet: 1.664 ± 0.902
3.329PheAsn: 3.329 ± 0.322
2.996PhePro: 2.996 ± 0.56
1.997PheGln: 1.997 ± 0.551
0.666PheArg: 0.666 ± 0.361
3.662PheSer: 3.662 ± 0.921
3.329PheThr: 3.329 ± 0.741
3.329PheVal: 3.329 ± 0.322
0.999PheTrp: 0.999 ± 0.541
1.664PheTyr: 1.664 ± 1.224
0.0PheXaa: 0.0 ± 0.0
Gly
4.66GlyAla: 4.66 ± 0.664
0.999GlyCys: 0.999 ± 0.541
3.995GlyAsp: 3.995 ± 0.493
2.33GlyGlu: 2.33 ± 0.332
2.663GlyPhe: 2.663 ± 0.38
0.999GlyGly: 0.999 ± 0.541
0.999GlyHis: 0.999 ± 0.522
4.993GlyIle: 4.993 ± 0.58
3.329GlyLys: 3.329 ± 0.209
4.993GlyLeu: 4.993 ± 1.642
0.666GlyMet: 0.666 ± 0.702
4.66GlyAsn: 4.66 ± 0.132
1.664GlyPro: 1.664 ± 0.161
3.329GlyGln: 3.329 ± 0.322
2.996GlyArg: 2.996 ± 1.092
3.662GlySer: 3.662 ± 1.452
4.993GlyThr: 4.993 ± 1.546
2.33GlyVal: 2.33 ± 1.262
0.666GlyTrp: 0.666 ± 0.171
2.996GlyTyr: 2.996 ± 0.029
0.0GlyXaa: 0.0 ± 0.0
His
3.329HisAla: 3.329 ± 2.448
0.666HisCys: 0.666 ± 0.702
0.666HisAsp: 0.666 ± 0.361
0.999HisGlu: 0.999 ± 0.01
1.332HisPhe: 1.332 ± 0.19
1.332HisGly: 1.332 ± 0.19
0.333HisHis: 0.333 ± 0.351
1.332HisIle: 1.332 ± 0.721
1.997HisLys: 1.997 ± 1.082
2.996HisLeu: 2.996 ± 0.029
0.0HisMet: 0.0 ± 0.0
0.999HisAsn: 0.999 ± 0.541
1.664HisPro: 1.664 ± 0.902
1.332HisGln: 1.332 ± 0.341
0.999HisArg: 0.999 ± 0.01
1.664HisSer: 1.664 ± 0.161
0.999HisThr: 0.999 ± 0.522
0.666HisVal: 0.666 ± 0.171
0.999HisTrp: 0.999 ± 0.541
0.333HisTyr: 0.333 ± 0.18
0.0HisXaa: 0.0 ± 0.0
Ile
4.66IleAla: 4.66 ± 0.664
0.999IleCys: 0.999 ± 0.541
1.332IleAsp: 1.332 ± 0.19
4.66IleGlu: 4.66 ± 0.399
2.663IlePhe: 2.663 ± 0.38
3.662IleGly: 3.662 ± 0.39
1.997IleHis: 1.997 ± 0.019
2.33IleIle: 2.33 ± 0.731
0.333IleLys: 0.333 ± 0.18
5.659IleLeu: 5.659 ± 2.535
0.999IleMet: 0.999 ± 0.01
4.993IleAsn: 4.993 ± 0.048
3.995IlePro: 3.995 ± 0.493
1.332IleGln: 1.332 ± 0.873
3.329IleArg: 3.329 ± 0.209
3.329IleSer: 3.329 ± 0.741
2.996IleThr: 2.996 ± 0.502
3.995IleVal: 3.995 ± 0.493
0.333IleTrp: 0.333 ± 0.351
2.996IleTyr: 2.996 ± 0.502
0.0IleXaa: 0.0 ± 0.0
Lys
2.996LysAla: 2.996 ± 0.56
1.664LysCys: 1.664 ± 0.161
2.996LysAsp: 2.996 ± 0.029
3.662LysGlu: 3.662 ± 0.921
2.33LysPhe: 2.33 ± 0.332
2.996LysGly: 2.996 ± 1.092
1.997LysHis: 1.997 ± 0.512
3.329LysIle: 3.329 ± 0.741
1.664LysLys: 1.664 ± 0.37
5.992LysLeu: 5.992 ± 1.121
1.664LysMet: 1.664 ± 0.278
1.997LysAsn: 1.997 ± 0.019
2.33LysPro: 2.33 ± 0.2
2.996LysGln: 2.996 ± 0.502
3.329LysArg: 3.329 ± 0.741
2.663LysSer: 2.663 ± 1.443
3.329LysThr: 3.329 ± 1.272
2.663LysVal: 2.663 ± 0.38
0.333LysTrp: 0.333 ± 0.18
1.332LysTyr: 1.332 ± 0.19
0.0LysXaa: 0.0 ± 0.0
Leu
5.326LeuAla: 5.326 ± 0.834
0.333LeuCys: 0.333 ± 0.18
3.662LeuAsp: 3.662 ± 0.39
4.66LeuGlu: 4.66 ± 0.931
3.662LeuPhe: 3.662 ± 0.673
5.992LeuGly: 5.992 ± 3.246
1.664LeuHis: 1.664 ± 0.902
4.328LeuIle: 4.328 ± 2.345
6.658LeuLys: 6.658 ± 0.113
6.658LeuLeu: 6.658 ± 2.013
1.997LeuMet: 1.997 ± 0.551
3.662LeuAsn: 3.662 ± 0.142
5.659LeuPro: 5.659 ± 1.185
2.663LeuGln: 2.663 ± 0.151
4.993LeuArg: 4.993 ± 0.483
5.992LeuSer: 5.992 ± 0.058
7.989LeuThr: 7.989 ± 1.14
6.658LeuVal: 6.658 ± 1.707
0.999LeuTrp: 0.999 ± 0.541
3.995LeuTyr: 3.995 ± 0.493
0.0LeuXaa: 0.0 ± 0.0
Met
0.333MetAla: 0.333 ± 0.351
0.999MetCys: 0.999 ± 0.522
2.663MetAsp: 2.663 ± 1.214
0.999MetGlu: 0.999 ± 0.522
1.332MetPhe: 1.332 ± 0.19
1.332MetGly: 1.332 ± 0.721
0.0MetHis: 0.0 ± 0.0
0.999MetIle: 0.999 ± 0.541
0.666MetLys: 0.666 ± 0.361
2.33MetLeu: 2.33 ± 0.731
0.333MetMet: 0.333 ± 0.119
2.33MetAsn: 2.33 ± 0.731
0.999MetPro: 0.999 ± 0.522
1.332MetGln: 1.332 ± 0.721
0.333MetArg: 0.333 ± 0.351
2.663MetSer: 2.663 ± 0.683
2.663MetThr: 2.663 ± 0.38
0.999MetVal: 0.999 ± 0.541
0.333MetTrp: 0.333 ± 0.351
0.666MetTyr: 0.666 ± 0.361
0.0MetXaa: 0.0 ± 0.0
Asn
2.996AsnAla: 2.996 ± 0.029
1.997AsnCys: 1.997 ± 0.019
1.332AsnAsp: 1.332 ± 0.19
0.999AsnGlu: 0.999 ± 0.01
3.329AsnPhe: 3.329 ± 0.741
4.328AsnGly: 4.328 ± 0.313
0.666AsnHis: 0.666 ± 0.171
2.663AsnIle: 2.663 ± 0.151
2.663AsnLys: 2.663 ± 0.38
6.325AsnLeu: 6.325 ± 0.77
1.332AsnMet: 1.332 ± 0.341
1.664AsnAsn: 1.664 ± 1.224
4.328AsnPro: 4.328 ± 0.844
2.996AsnGln: 2.996 ± 0.029
2.33AsnArg: 2.33 ± 0.731
2.996AsnSer: 2.996 ± 1.565
4.993AsnThr: 4.993 ± 1.546
1.997AsnVal: 1.997 ± 0.019
0.999AsnTrp: 0.999 ± 0.522
1.997AsnTyr: 1.997 ± 0.551
0.0AsnXaa: 0.0 ± 0.0
Pro
3.329ProAla: 3.329 ± 0.209
0.999ProCys: 0.999 ± 0.541
4.328ProAsp: 4.328 ± 0.219
2.996ProGlu: 2.996 ± 0.502
1.332ProPhe: 1.332 ± 0.19
3.995ProGly: 3.995 ± 2.087
1.332ProHis: 1.332 ± 0.341
2.663ProIle: 2.663 ± 0.683
3.662ProLys: 3.662 ± 0.39
3.662ProLeu: 3.662 ± 1.205
0.999ProMet: 0.999 ± 0.522
1.997ProAsn: 1.997 ± 0.019
0.999ProPro: 0.999 ± 0.522
1.664ProGln: 1.664 ± 0.161
1.997ProArg: 1.997 ± 0.512
3.662ProSer: 3.662 ± 0.673
3.662ProThr: 3.662 ± 0.39
4.993ProVal: 4.993 ± 0.483
1.332ProTrp: 1.332 ± 0.873
1.997ProTyr: 1.997 ± 0.512
0.0ProXaa: 0.0 ± 0.0
Gln
2.33GlnAla: 2.33 ± 0.2
0.0GlnCys: 0.0 ± 0.0
1.997GlnAsp: 1.997 ± 1.082
2.33GlnGlu: 2.33 ± 0.332
2.996GlnPhe: 2.996 ± 1.034
1.664GlnGly: 1.664 ± 0.37
0.999GlnHis: 0.999 ± 0.541
2.663GlnIle: 2.663 ± 0.151
2.996GlnLys: 2.996 ± 0.56
2.663GlnLeu: 2.663 ± 0.151
2.663GlnMet: 2.663 ± 0.683
1.997GlnAsn: 1.997 ± 0.019
1.664GlnPro: 1.664 ± 1.224
2.996GlnGln: 2.996 ± 0.56
1.997GlnArg: 1.997 ± 0.019
2.663GlnSer: 2.663 ± 0.38
5.659GlnThr: 5.659 ± 1.185
1.664GlnVal: 1.664 ± 0.37
0.0GlnTrp: 0.0 ± 0.0
1.664GlnTyr: 1.664 ± 0.902
0.0GlnXaa: 0.0 ± 0.0
Arg
3.329ArgAla: 3.329 ± 0.741
2.33ArgCys: 2.33 ± 0.2
2.996ArgAsp: 2.996 ± 0.029
0.999ArgGlu: 0.999 ± 0.522
3.662ArgPhe: 3.662 ± 0.921
1.664ArgGly: 1.664 ± 0.37
1.664ArgHis: 1.664 ± 0.161
4.993ArgIle: 4.993 ± 1.642
1.664ArgLys: 1.664 ± 0.37
3.662ArgLeu: 3.662 ± 0.39
0.666ArgMet: 0.666 ± 0.171
0.666ArgAsn: 0.666 ± 0.702
3.662ArgPro: 3.662 ± 0.39
1.997ArgGln: 1.997 ± 0.019
1.664ArgArg: 1.664 ± 0.37
3.662ArgSer: 3.662 ± 0.673
2.33ArgThr: 2.33 ± 1.395
3.662ArgVal: 3.662 ± 0.921
0.666ArgTrp: 0.666 ± 0.361
0.999ArgTyr: 0.999 ± 1.053
0.0ArgXaa: 0.0 ± 0.0
Ser
5.326SerAla: 5.326 ± 0.229
0.999SerCys: 0.999 ± 0.01
2.996SerAsp: 2.996 ± 2.097
4.66SerGlu: 4.66 ± 1.462
1.997SerPhe: 1.997 ± 0.019
4.66SerGly: 4.66 ± 0.664
1.332SerHis: 1.332 ± 0.721
2.663SerIle: 2.663 ± 0.911
3.662SerLys: 3.662 ± 0.39
6.991SerLeu: 6.991 ± 0.995
1.332SerMet: 1.332 ± 0.721
3.995SerAsn: 3.995 ± 0.039
2.663SerPro: 2.663 ± 0.151
2.663SerGln: 2.663 ± 0.151
2.996SerArg: 2.996 ± 1.034
4.66SerSer: 4.66 ± 0.132
7.324SerThr: 7.324 ± 2.409
4.66SerVal: 4.66 ± 0.132
1.332SerTrp: 1.332 ± 0.341
1.997SerTyr: 1.997 ± 0.019
0.0SerXaa: 0.0 ± 0.0
Thr
3.662ThrAla: 3.662 ± 1.205
1.332ThrCys: 1.332 ± 0.19
3.662ThrAsp: 3.662 ± 0.921
5.326ThrGlu: 5.326 ± 1.291
5.326ThrPhe: 5.326 ± 0.229
3.662ThrGly: 3.662 ± 0.921
0.666ThrHis: 0.666 ± 0.361
3.662ThrIle: 3.662 ± 1.205
3.995ThrLys: 3.995 ± 0.039
8.322ThrLeu: 8.322 ± 0.789
1.997ThrMet: 1.997 ± 0.019
4.66ThrAsn: 4.66 ± 0.132
5.659ThrPro: 5.659 ± 3.311
3.662ThrGln: 3.662 ± 0.39
2.996ThrArg: 2.996 ± 0.029
3.995ThrSer: 3.995 ± 2.087
5.659ThrThr: 5.659 ± 0.123
3.995ThrVal: 3.995 ± 2.087
0.333ThrTrp: 0.333 ± 0.18
3.995ThrTyr: 3.995 ± 0.57
0.0ThrXaa: 0.0 ± 0.0
Val
3.329ValAla: 3.329 ± 1.385
0.333ValCys: 0.333 ± 0.351
5.659ValAsp: 5.659 ± 0.409
5.992ValGlu: 5.992 ± 0.474
1.664ValPhe: 1.664 ± 0.161
2.996ValGly: 2.996 ± 1.092
0.999ValHis: 0.999 ± 0.01
2.996ValIle: 2.996 ± 0.029
2.996ValLys: 2.996 ± 0.029
3.995ValLeu: 3.995 ± 0.039
1.332ValMet: 1.332 ± 0.721
3.329ValAsn: 3.329 ± 0.854
1.664ValPro: 1.664 ± 0.692
2.996ValGln: 2.996 ± 0.029
3.995ValArg: 3.995 ± 0.57
3.995ValSer: 3.995 ± 1.024
4.328ValThr: 4.328 ± 0.313
1.997ValVal: 1.997 ± 0.019
0.999ValTrp: 0.999 ± 0.01
1.997ValTyr: 1.997 ± 0.512
0.0ValXaa: 0.0 ± 0.0
Trp
0.999TrpAla: 0.999 ± 0.522
0.666TrpCys: 0.666 ± 0.361
1.664TrpAsp: 1.664 ± 0.692
0.666TrpGlu: 0.666 ± 0.702
0.333TrpPhe: 0.333 ± 0.18
0.666TrpGly: 0.666 ± 0.171
0.0TrpHis: 0.0 ± 0.0
0.333TrpIle: 0.333 ± 0.18
1.997TrpLys: 1.997 ± 1.082
0.666TrpLeu: 0.666 ± 0.361
0.333TrpMet: 0.333 ± 0.18
0.666TrpAsn: 0.666 ± 0.361
0.0TrpPro: 0.0 ± 0.0
0.999TrpGln: 0.999 ± 0.541
0.666TrpArg: 0.666 ± 0.702
0.999TrpSer: 0.999 ± 0.522
1.332TrpThr: 1.332 ± 0.341
0.999TrpVal: 0.999 ± 0.01
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.33TyrAla: 2.33 ± 0.332
0.333TyrCys: 0.333 ± 0.18
1.664TyrAsp: 1.664 ± 0.37
1.664TyrGlu: 1.664 ± 0.37
2.33TyrPhe: 2.33 ± 0.332
2.33TyrGly: 2.33 ± 0.332
2.663TyrHis: 2.663 ± 0.38
1.332TyrIle: 1.332 ± 0.341
1.332TyrLys: 1.332 ± 0.19
1.664TyrLeu: 1.664 ± 0.161
0.666TyrMet: 0.666 ± 0.171
2.996TyrAsn: 2.996 ± 0.56
2.33TyrPro: 2.33 ± 0.2
0.999TyrGln: 0.999 ± 0.01
2.663TyrArg: 2.663 ± 0.38
2.33TyrSer: 2.33 ± 0.863
2.33TyrThr: 2.33 ± 0.2
2.33TyrVal: 2.33 ± 0.863
1.332TyrTrp: 1.332 ± 0.341
1.997TyrTyr: 1.997 ± 0.512
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (3005 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski