Amino acid dipepetide frequency for Tortoise microvirus 26

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.508AlaAla: 4.508 ± 2.669
1.503AlaCys: 1.503 ± 1.434
5.259AlaAsp: 5.259 ± 2.397
3.005AlaGlu: 3.005 ± 1.89
2.254AlaPhe: 2.254 ± 3.173
4.508AlaGly: 4.508 ± 2.669
0.0AlaHis: 0.0 ± 0.0
0.0AlaIle: 0.0 ± 0.0
3.005AlaLys: 3.005 ± 1.723
3.757AlaLeu: 3.757 ± 0.746
0.0AlaMet: 0.0 ± 0.0
3.005AlaAsn: 3.005 ± 1.424
3.005AlaPro: 3.005 ± 1.397
3.757AlaGln: 3.757 ± 2.718
2.254AlaArg: 2.254 ± 1.459
2.254AlaSer: 2.254 ± 0.937
2.254AlaThr: 2.254 ± 1.008
3.757AlaVal: 3.757 ± 1.938
0.751AlaTrp: 0.751 ± 0.53
4.508AlaTyr: 4.508 ± 1.461
0.0AlaXaa: 0.0 ± 0.0
Cys
0.751CysAla: 0.751 ± 0.53
0.0CysCys: 0.0 ± 0.0
0.751CysAsp: 0.751 ± 0.53
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
2.254CysGly: 2.254 ± 1.04
0.751CysHis: 0.751 ± 0.53
0.0CysIle: 0.0 ± 0.0
0.751CysLys: 0.751 ± 0.717
0.751CysLeu: 0.751 ± 1.492
0.0CysMet: 0.0 ± 0.0
1.503CysAsn: 1.503 ± 0.719
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.751CysArg: 0.751 ± 0.717
0.751CysSer: 0.751 ± 0.717
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.751CysTyr: 0.751 ± 0.717
0.0CysXaa: 0.0 ± 0.0
Asp
3.757AspAla: 3.757 ± 1.207
0.0AspCys: 0.0 ± 0.0
3.005AspAsp: 3.005 ± 1.397
6.762AspGlu: 6.762 ± 3.581
6.762AspPhe: 6.762 ± 3.625
0.0AspGly: 0.0 ± 0.0
0.751AspHis: 0.751 ± 0.53
9.016AspIle: 9.016 ± 2.057
6.762AspLys: 6.762 ± 3.086
5.259AspLeu: 5.259 ± 1.763
3.757AspMet: 3.757 ± 1.651
3.005AspAsn: 3.005 ± 1.478
2.254AspPro: 2.254 ± 1.151
1.503AspGln: 1.503 ± 0.719
0.751AspArg: 0.751 ± 0.53
4.508AspSer: 4.508 ± 2.72
2.254AspThr: 2.254 ± 1.459
0.751AspVal: 0.751 ± 0.717
0.751AspTrp: 0.751 ± 0.717
3.757AspTyr: 3.757 ± 1.046
0.0AspXaa: 0.0 ± 0.0
Glu
3.005GluAla: 3.005 ± 1.449
1.503GluCys: 1.503 ± 1.371
4.508GluAsp: 4.508 ± 1.757
2.254GluGlu: 2.254 ± 1.601
5.259GluPhe: 5.259 ± 3.096
0.751GluGly: 0.751 ± 0.717
2.254GluHis: 2.254 ± 1.757
0.751GluIle: 0.751 ± 0.717
3.757GluLys: 3.757 ± 1.443
3.757GluLeu: 3.757 ± 1.17
3.757GluMet: 3.757 ± 1.22
0.751GluAsn: 0.751 ± 0.723
1.503GluPro: 1.503 ± 1.06
4.508GluGln: 4.508 ± 1.573
3.005GluArg: 3.005 ± 1.086
0.751GluSer: 0.751 ± 0.717
1.503GluThr: 1.503 ± 0.944
3.005GluVal: 3.005 ± 0.998
0.751GluTrp: 0.751 ± 0.717
6.762GluTyr: 6.762 ± 1.309
0.0GluXaa: 0.0 ± 0.0
Phe
3.757PheAla: 3.757 ± 1.377
0.0PheCys: 0.0 ± 0.0
6.011PheAsp: 6.011 ± 4.356
0.751PheGlu: 0.751 ± 1.492
3.757PhePhe: 3.757 ± 2.761
4.508PheGly: 4.508 ± 1.31
0.0PheHis: 0.0 ± 0.0
2.254PheIle: 2.254 ± 1.04
5.259PheLys: 5.259 ± 1.565
0.751PheLeu: 0.751 ± 0.53
0.751PheMet: 0.751 ± 1.191
5.259PheAsn: 5.259 ± 2.349
1.503PhePro: 1.503 ± 1.06
3.757PheGln: 3.757 ± 1.046
1.503PheArg: 1.503 ± 1.197
5.259PheSer: 5.259 ± 2.969
3.005PheThr: 3.005 ± 0.823
3.005PheVal: 3.005 ± 1.438
0.751PheTrp: 0.751 ± 0.53
2.254PheTyr: 2.254 ± 0.937
0.0PheXaa: 0.0 ± 0.0
Gly
3.005GlyAla: 3.005 ± 2.893
0.0GlyCys: 0.0 ± 0.0
1.503GlyAsp: 1.503 ± 1.371
3.757GlyGlu: 3.757 ± 1.17
2.254GlyPhe: 2.254 ± 1.32
6.011GlyGly: 6.011 ± 2.795
0.751GlyHis: 0.751 ± 0.53
6.011GlyIle: 6.011 ± 1.735
2.254GlyLys: 2.254 ± 1.232
9.016GlyLeu: 9.016 ± 2.287
0.751GlyMet: 0.751 ± 0.53
4.508GlyAsn: 4.508 ± 1.347
2.254GlyPro: 2.254 ± 1.008
2.254GlyGln: 2.254 ± 1.635
3.005GlyArg: 3.005 ± 1.397
3.757GlySer: 3.757 ± 1.974
1.503GlyThr: 1.503 ± 0.699
2.254GlyVal: 2.254 ± 1.04
1.503GlyTrp: 1.503 ± 1.371
3.757GlyTyr: 3.757 ± 2.037
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.503HisGlu: 1.503 ± 0.719
0.0HisPhe: 0.0 ± 0.0
3.005HisGly: 3.005 ± 1.438
1.503HisHis: 1.503 ± 1.06
0.0HisIle: 0.0 ± 0.0
0.751HisLys: 0.751 ± 0.53
3.005HisLeu: 3.005 ± 1.182
1.503HisMet: 1.503 ± 0.678
1.503HisAsn: 1.503 ± 0.719
0.751HisPro: 0.751 ± 1.492
1.503HisGln: 1.503 ± 1.434
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
2.254HisTyr: 2.254 ± 1.335
0.0HisXaa: 0.0 ± 0.0
Ile
0.751IleAla: 0.751 ± 1.492
0.0IleCys: 0.0 ± 0.0
6.762IleAsp: 6.762 ± 2.197
2.254IleGlu: 2.254 ± 0.655
6.011IlePhe: 6.011 ± 2.265
3.757IleGly: 3.757 ± 0.746
0.751IleHis: 0.751 ± 0.717
3.757IleIle: 3.757 ± 1.435
2.254IleLys: 2.254 ± 2.151
4.508IleLeu: 4.508 ± 1.384
2.254IleMet: 2.254 ± 1.04
3.757IleAsn: 3.757 ± 1.651
3.005IlePro: 3.005 ± 1.451
1.503IleGln: 1.503 ± 1.151
3.005IleArg: 3.005 ± 0.823
7.513IleSer: 7.513 ± 1.543
2.254IleThr: 2.254 ± 1.012
0.751IleVal: 0.751 ± 1.492
0.751IleTrp: 0.751 ± 0.53
3.757IleTyr: 3.757 ± 3.087
0.0IleXaa: 0.0 ± 0.0
Lys
5.259LysAla: 5.259 ± 3.967
1.503LysCys: 1.503 ± 1.434
4.508LysAsp: 4.508 ± 1.089
3.757LysGlu: 3.757 ± 1.437
3.005LysPhe: 3.005 ± 1.438
2.254LysGly: 2.254 ± 1.448
2.254LysHis: 2.254 ± 0.655
3.005LysIle: 3.005 ± 1.93
3.005LysLys: 3.005 ± 1.479
3.757LysLeu: 3.757 ± 2.973
1.503LysMet: 1.503 ± 1.371
1.503LysAsn: 1.503 ± 0.719
1.503LysPro: 1.503 ± 1.06
4.508LysGln: 4.508 ± 2.285
2.254LysArg: 2.254 ± 1.757
9.016LysSer: 9.016 ± 4.246
3.757LysThr: 3.757 ± 1.435
3.757LysVal: 3.757 ± 2.506
1.503LysTrp: 1.503 ± 0.699
3.757LysTyr: 3.757 ± 1.357
0.0LysXaa: 0.0 ± 0.0
Leu
3.757LeuAla: 3.757 ± 1.309
0.751LeuCys: 0.751 ± 0.53
6.011LeuAsp: 6.011 ± 1.647
2.254LeuGlu: 2.254 ± 2.151
3.757LeuPhe: 3.757 ± 1.97
6.762LeuGly: 6.762 ± 3.789
1.503LeuHis: 1.503 ± 0.719
4.508LeuIle: 4.508 ± 1.07
6.762LeuLys: 6.762 ± 3.079
6.762LeuLeu: 6.762 ± 2.583
1.503LeuMet: 1.503 ± 1.193
3.005LeuAsn: 3.005 ± 1.438
3.757LeuPro: 3.757 ± 1.435
6.762LeuGln: 6.762 ± 0.995
6.762LeuArg: 6.762 ± 1.718
6.762LeuSer: 6.762 ± 2.213
3.005LeuThr: 3.005 ± 1.784
2.254LeuVal: 2.254 ± 1.012
1.503LeuTrp: 1.503 ± 1.06
3.005LeuTyr: 3.005 ± 1.438
0.0LeuXaa: 0.0 ± 0.0
Met
0.751MetAla: 0.751 ± 0.53
0.0MetCys: 0.0 ± 0.0
0.751MetAsp: 0.751 ± 0.723
1.503MetGlu: 1.503 ± 1.197
1.503MetPhe: 1.503 ± 1.447
2.254MetGly: 2.254 ± 1.008
0.0MetHis: 0.0 ± 0.0
0.751MetIle: 0.751 ± 0.53
2.254MetLys: 2.254 ± 1.335
1.503MetLeu: 1.503 ± 0.699
0.0MetMet: 0.0 ± 0.0
1.503MetAsn: 1.503 ± 1.67
1.503MetPro: 1.503 ± 0.944
1.503MetGln: 1.503 ± 0.699
1.503MetArg: 1.503 ± 1.06
2.254MetSer: 2.254 ± 0.655
2.254MetThr: 2.254 ± 1.04
0.751MetVal: 0.751 ± 0.53
0.0MetTrp: 0.0 ± 0.0
0.751MetTyr: 0.751 ± 1.492
0.0MetXaa: 0.0 ± 0.0
Asn
2.254AsnAla: 2.254 ± 2.17
0.0AsnCys: 0.0 ± 0.0
3.005AsnAsp: 3.005 ± 1.478
2.254AsnGlu: 2.254 ± 1.232
0.751AsnPhe: 0.751 ± 0.723
0.751AsnGly: 0.751 ± 1.492
0.0AsnHis: 0.0 ± 0.0
3.005AsnIle: 3.005 ± 1.182
5.259AsnLys: 5.259 ± 3.43
10.518AsnLeu: 10.518 ± 2.802
2.254AsnMet: 2.254 ± 1.04
4.508AsnAsn: 4.508 ± 1.31
4.508AsnPro: 4.508 ± 1.776
3.005AsnGln: 3.005 ± 1.451
3.757AsnArg: 3.757 ± 1.309
6.011AsnSer: 6.011 ± 1.398
2.254AsnThr: 2.254 ± 1.601
3.005AsnVal: 3.005 ± 1.695
0.751AsnTrp: 0.751 ± 0.53
2.254AsnTyr: 2.254 ± 0.655
0.0AsnXaa: 0.0 ± 0.0
Pro
2.254ProAla: 2.254 ± 1.008
0.0ProCys: 0.0 ± 0.0
0.751ProAsp: 0.751 ± 0.723
2.254ProGlu: 2.254 ± 1.151
3.757ProPhe: 3.757 ± 1.17
3.757ProGly: 3.757 ± 2.65
1.503ProHis: 1.503 ± 0.719
6.762ProIle: 6.762 ± 2.809
3.005ProLys: 3.005 ± 0.847
1.503ProLeu: 1.503 ± 0.699
0.0ProMet: 0.0 ± 0.0
3.005ProAsn: 3.005 ± 1.695
4.508ProPro: 4.508 ± 1.888
3.005ProGln: 3.005 ± 1.397
3.757ProArg: 3.757 ± 2.65
4.508ProSer: 4.508 ± 1.07
1.503ProThr: 1.503 ± 0.944
3.757ProVal: 3.757 ± 1.309
0.0ProTrp: 0.0 ± 0.0
2.254ProTyr: 2.254 ± 1.335
0.0ProXaa: 0.0 ± 0.0
Gln
3.005GlnAla: 3.005 ± 2.01
0.0GlnCys: 0.0 ± 0.0
4.508GlnAsp: 4.508 ± 1.806
5.259GlnGlu: 5.259 ± 1.637
0.0GlnPhe: 0.0 ± 0.0
6.011GlnGly: 6.011 ± 2.119
0.0GlnHis: 0.0 ± 0.0
1.503GlnIle: 1.503 ± 1.197
3.757GlnLys: 3.757 ± 1.294
3.757GlnLeu: 3.757 ± 1.842
2.254GlnMet: 2.254 ± 2.17
5.259GlnAsn: 5.259 ± 2.266
3.005GlnPro: 3.005 ± 0.998
3.757GlnGln: 3.757 ± 1.737
5.259GlnArg: 5.259 ± 1.876
4.508GlnSer: 4.508 ± 1.07
2.254GlnThr: 2.254 ± 1.448
2.254GlnVal: 2.254 ± 1.04
1.503GlnTrp: 1.503 ± 1.06
0.751GlnTyr: 0.751 ± 1.01
0.0GlnXaa: 0.0 ± 0.0
Arg
3.757ArgAla: 3.757 ± 0.746
0.0ArgCys: 0.0 ± 0.0
3.757ArgAsp: 3.757 ± 1.969
2.254ArgGlu: 2.254 ± 1.42
1.503ArgPhe: 1.503 ± 0.944
1.503ArgGly: 1.503 ± 1.06
0.751ArgHis: 0.751 ± 0.717
4.508ArgIle: 4.508 ± 1.13
4.508ArgLys: 4.508 ± 2.533
4.508ArgLeu: 4.508 ± 2.025
0.0ArgMet: 0.0 ± 0.0
3.757ArgAsn: 3.757 ± 2.234
3.757ArgPro: 3.757 ± 1.377
0.751ArgGln: 0.751 ± 0.53
3.757ArgArg: 3.757 ± 0.746
4.508ArgSer: 4.508 ± 1.089
2.254ArgThr: 2.254 ± 1.151
2.254ArgVal: 2.254 ± 1.012
0.0ArgTrp: 0.0 ± 0.0
3.757ArgTyr: 3.757 ± 1.651
0.0ArgXaa: 0.0 ± 0.0
Ser
4.508SerAla: 4.508 ± 1.461
0.751SerCys: 0.751 ± 0.717
6.762SerAsp: 6.762 ± 1.389
3.005SerGlu: 3.005 ± 1.486
6.011SerPhe: 6.011 ± 2.205
4.508SerGly: 4.508 ± 2.443
2.254SerHis: 2.254 ± 0.655
6.762SerIle: 6.762 ± 2.675
6.011SerLys: 6.011 ± 1.04
7.513SerLeu: 7.513 ± 1.688
0.0SerMet: 0.0 ± 0.0
2.254SerAsn: 2.254 ± 1.601
6.011SerPro: 6.011 ± 2.434
3.005SerGln: 3.005 ± 1.608
1.503SerArg: 1.503 ± 0.944
3.005SerSer: 3.005 ± 0.998
6.762SerThr: 6.762 ± 3.648
3.757SerVal: 3.757 ± 1.149
0.751SerTrp: 0.751 ± 0.717
3.005SerTyr: 3.005 ± 1.479
0.0SerXaa: 0.0 ± 0.0
Thr
3.005ThrAla: 3.005 ± 1.451
0.0ThrCys: 0.0 ± 0.0
2.254ThrAsp: 2.254 ± 2.816
4.508ThrGlu: 4.508 ± 3.202
2.254ThrPhe: 2.254 ± 1.59
3.005ThrGly: 3.005 ± 1.178
0.0ThrHis: 0.0 ± 0.0
1.503ThrIle: 1.503 ± 1.67
3.005ThrLys: 3.005 ± 1.449
2.254ThrLeu: 2.254 ± 0.655
1.503ThrMet: 1.503 ± 1.045
3.005ThrAsn: 3.005 ± 0.998
3.005ThrPro: 3.005 ± 0.847
3.757ThrGln: 3.757 ± 2.789
0.0ThrArg: 0.0 ± 0.0
3.757ThrSer: 3.757 ± 1.377
3.757ThrThr: 3.757 ± 2.789
1.503ThrVal: 1.503 ± 1.197
0.0ThrTrp: 0.0 ± 0.0
2.254ThrTyr: 2.254 ± 1.04
0.0ThrXaa: 0.0 ± 0.0
Val
2.254ValAla: 2.254 ± 1.04
2.254ValCys: 2.254 ± 1.04
0.0ValAsp: 0.0 ± 0.0
2.254ValGlu: 2.254 ± 1.04
2.254ValPhe: 2.254 ± 1.448
2.254ValGly: 2.254 ± 1.77
0.0ValHis: 0.0 ± 0.0
3.005ValIle: 3.005 ± 1.207
1.503ValLys: 1.503 ± 1.197
3.757ValLeu: 3.757 ± 1.443
0.0ValMet: 0.0 ± 0.0
4.508ValAsn: 4.508 ± 0.979
3.005ValPro: 3.005 ± 1.486
3.005ValGln: 3.005 ± 1.451
3.005ValArg: 3.005 ± 1.182
2.254ValSer: 2.254 ± 1.008
3.005ValThr: 3.005 ± 1.784
4.508ValVal: 4.508 ± 2.76
0.751ValTrp: 0.751 ± 0.53
0.751ValTyr: 0.751 ± 0.717
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.751TrpAsp: 0.751 ± 0.53
2.254TrpGlu: 2.254 ± 1.59
0.751TrpPhe: 0.751 ± 0.717
0.0TrpGly: 0.0 ± 0.0
0.751TrpHis: 0.751 ± 0.53
1.503TrpIle: 1.503 ± 0.699
0.751TrpLys: 0.751 ± 1.492
0.751TrpLeu: 0.751 ± 0.53
0.0TrpMet: 0.0 ± 0.0
1.503TrpAsn: 1.503 ± 0.699
1.503TrpPro: 1.503 ± 0.719
0.751TrpGln: 0.751 ± 0.53
0.0TrpArg: 0.0 ± 0.0
2.254TrpSer: 2.254 ± 1.04
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.005TyrAla: 3.005 ± 0.847
1.503TyrCys: 1.503 ± 1.06
4.508TyrAsp: 4.508 ± 4.04
2.254TyrGlu: 2.254 ± 1.32
3.005TyrPhe: 3.005 ± 1.207
2.254TyrGly: 2.254 ± 1.232
1.503TyrHis: 1.503 ± 1.434
0.751TyrIle: 0.751 ± 1.01
0.751TyrLys: 0.751 ± 0.53
3.757TyrLeu: 3.757 ± 1.046
0.751TyrMet: 0.751 ± 0.717
3.005TyrAsn: 3.005 ± 1.213
1.503TyrPro: 1.503 ± 0.719
6.011TyrGln: 6.011 ± 1.647
6.011TyrArg: 6.011 ± 2.608
4.508TyrSer: 4.508 ± 1.865
0.751TyrThr: 0.751 ± 0.53
3.005TyrVal: 3.005 ± 1.478
1.503TyrTrp: 1.503 ± 0.699
3.757TyrTyr: 3.757 ± 1.708
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1332 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski