Amino acid dipepetide frequency for Tortoise microvirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.605AlaAla: 7.605 ± 5.158
1.63AlaCys: 1.63 ± 2.01
2.173AlaAsp: 2.173 ± 0.875
3.259AlaGlu: 3.259 ± 1.437
1.086AlaPhe: 1.086 ± 0.828
4.889AlaGly: 4.889 ± 3.702
2.716AlaHis: 2.716 ± 1.916
5.432AlaIle: 5.432 ± 2.986
3.259AlaLys: 3.259 ± 1.364
5.432AlaLeu: 5.432 ± 1.678
1.63AlaMet: 1.63 ± 1.017
2.716AlaAsn: 2.716 ± 1.132
2.173AlaPro: 2.173 ± 1.57
4.889AlaGln: 4.889 ± 3.24
3.802AlaArg: 3.802 ± 1.32
4.345AlaSer: 4.345 ± 1.303
5.432AlaThr: 5.432 ± 1.816
2.173AlaVal: 2.173 ± 0.427
0.0AlaTrp: 0.0 ± 0.0
5.432AlaTyr: 5.432 ± 1.129
0.0AlaXaa: 0.0 ± 0.0
Cys
1.63CysAla: 1.63 ± 0.924
0.0CysCys: 0.0 ± 0.0
1.086CysAsp: 1.086 ± 0.48
2.173CysGlu: 2.173 ± 1.053
1.63CysPhe: 1.63 ± 1.179
0.543CysGly: 0.543 ± 0.818
0.0CysHis: 0.0 ± 0.0
1.086CysIle: 1.086 ± 0.622
1.63CysLys: 1.63 ± 0.675
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
1.086CysAsn: 1.086 ± 0.48
0.543CysPro: 0.543 ± 0.364
0.0CysGln: 0.0 ± 0.0
1.086CysArg: 1.086 ± 0.828
1.086CysSer: 1.086 ± 0.885
1.086CysThr: 1.086 ± 0.706
2.716CysVal: 2.716 ± 2.052
0.543CysTrp: 0.543 ± 0.512
1.086CysTyr: 1.086 ± 0.885
0.0CysXaa: 0.0 ± 0.0
Asp
4.345AspAla: 4.345 ± 1.621
1.086AspCys: 1.086 ± 0.885
2.173AspAsp: 2.173 ± 1.457
2.716AspGlu: 2.716 ± 1.132
4.889AspPhe: 4.889 ± 1.643
3.802AspGly: 3.802 ± 2.014
0.543AspHis: 0.543 ± 0.364
3.802AspIle: 3.802 ± 0.732
3.259AspLys: 3.259 ± 0.817
2.716AspLeu: 2.716 ± 1.501
3.259AspMet: 3.259 ± 1.832
1.63AspAsn: 1.63 ± 0.919
1.086AspPro: 1.086 ± 0.729
1.63AspGln: 1.63 ± 0.39
1.63AspArg: 1.63 ± 0.924
3.259AspSer: 3.259 ± 0.78
2.173AspThr: 2.173 ± 0.961
2.716AspVal: 2.716 ± 0.498
0.543AspTrp: 0.543 ± 0.364
3.259AspTyr: 3.259 ± 1.02
0.0AspXaa: 0.0 ± 0.0
Glu
2.173GluAla: 2.173 ± 1.57
0.0GluCys: 0.0 ± 0.0
3.259GluAsp: 3.259 ± 1.441
2.716GluGlu: 2.716 ± 0.692
3.802GluPhe: 3.802 ± 1.366
0.0GluGly: 0.0 ± 0.0
1.086GluHis: 1.086 ± 0.506
2.716GluIle: 2.716 ± 1.399
5.432GluLys: 5.432 ± 2.326
4.345GluLeu: 4.345 ± 2.325
1.086GluMet: 1.086 ± 1.513
2.716GluAsn: 2.716 ± 1.675
1.086GluPro: 1.086 ± 0.706
2.173GluGln: 2.173 ± 0.954
1.086GluArg: 1.086 ± 0.959
4.889GluSer: 4.889 ± 1.479
1.63GluThr: 1.63 ± 0.797
3.259GluVal: 3.259 ± 1.02
0.0GluTrp: 0.0 ± 0.0
4.889GluTyr: 4.889 ± 1.979
0.0GluXaa: 0.0 ± 0.0
Phe
3.802PheAla: 3.802 ± 0.689
2.173PheCys: 2.173 ± 1.655
3.802PheAsp: 3.802 ± 1.468
1.63PheGlu: 1.63 ± 1.406
3.802PhePhe: 3.802 ± 2.244
3.802PheGly: 3.802 ± 1.826
0.543PheHis: 0.543 ± 0.512
4.345PheIle: 4.345 ± 1.427
3.802PheLys: 3.802 ± 1.79
5.432PheLeu: 5.432 ± 0.988
0.0PheMet: 0.0 ± 0.0
4.345PheAsn: 4.345 ± 1.529
3.802PhePro: 3.802 ± 1.804
0.543PheGln: 0.543 ± 0.364
3.802PheArg: 3.802 ± 1.334
3.259PheSer: 3.259 ± 0.602
2.173PheThr: 2.173 ± 0.954
4.345PheVal: 4.345 ± 1.705
0.0PheTrp: 0.0 ± 0.0
1.086PheTyr: 1.086 ± 0.959
0.0PheXaa: 0.0 ± 0.0
Gly
3.802GlyAla: 3.802 ± 2.037
0.543GlyCys: 0.543 ± 0.364
4.345GlyAsp: 4.345 ± 1.908
2.173GlyGlu: 2.173 ± 1.442
2.173GlyPhe: 2.173 ± 0.982
3.259GlyGly: 3.259 ± 0.755
1.086GlyHis: 1.086 ± 0.622
4.345GlyIle: 4.345 ± 1.354
4.345GlyLys: 4.345 ± 2.947
7.605GlyLeu: 7.605 ± 2.597
1.63GlyMet: 1.63 ± 0.797
2.173GlyAsn: 2.173 ± 1.012
0.0GlyPro: 0.0 ± 0.0
2.716GlyGln: 2.716 ± 0.692
2.173GlyArg: 2.173 ± 0.954
5.432GlySer: 5.432 ± 1.652
5.432GlyThr: 5.432 ± 1.942
3.802GlyVal: 3.802 ± 1.366
0.0GlyTrp: 0.0 ± 0.0
3.259GlyTyr: 3.259 ± 1.63
0.0GlyXaa: 0.0 ± 0.0
His
1.086HisAla: 1.086 ± 1.024
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.543HisPhe: 0.543 ± 0.364
0.543HisGly: 0.543 ± 0.364
0.0HisHis: 0.0 ± 0.0
1.086HisIle: 1.086 ± 1.024
0.543HisLys: 0.543 ± 0.512
1.086HisLeu: 1.086 ± 0.506
1.086HisMet: 1.086 ± 0.587
1.086HisAsn: 1.086 ± 1.024
1.086HisPro: 1.086 ± 1.024
0.543HisGln: 0.543 ± 0.364
0.543HisArg: 0.543 ± 0.512
0.543HisSer: 0.543 ± 0.818
0.0HisThr: 0.0 ± 0.0
1.63HisVal: 1.63 ± 0.924
0.0HisTrp: 0.0 ± 0.0
3.259HisTyr: 3.259 ± 1.847
0.0HisXaa: 0.0 ± 0.0
Ile
3.259IleAla: 3.259 ± 1.299
0.543IleCys: 0.543 ± 0.364
2.173IleAsp: 2.173 ± 0.652
3.259IleGlu: 3.259 ± 0.804
2.173IlePhe: 2.173 ± 1.23
8.148IleGly: 8.148 ± 2.062
0.0IleHis: 0.0 ± 0.0
1.63IleIle: 1.63 ± 0.682
3.802IleLys: 3.802 ± 2.219
3.259IleLeu: 3.259 ± 1.566
2.173IleMet: 2.173 ± 0.926
5.975IleAsn: 5.975 ± 1.802
2.716IlePro: 2.716 ± 1.366
2.173IleGln: 2.173 ± 1.137
3.259IleArg: 3.259 ± 0.755
5.975IleSer: 5.975 ± 1.174
2.716IleThr: 2.716 ± 0.662
1.086IleVal: 1.086 ± 0.779
1.086IleTrp: 1.086 ± 0.622
2.716IleTyr: 2.716 ± 1.927
0.0IleXaa: 0.0 ± 0.0
Lys
4.345LysAla: 4.345 ± 2.603
2.716LysCys: 2.716 ± 1.791
3.259LysAsp: 3.259 ± 0.78
2.716LysGlu: 2.716 ± 0.972
4.345LysPhe: 4.345 ± 2.076
4.345LysGly: 4.345 ± 1.768
0.543LysHis: 0.543 ± 0.512
2.716LysIle: 2.716 ± 1.807
3.802LysLys: 3.802 ± 1.998
5.432LysLeu: 5.432 ± 3.398
0.543LysMet: 0.543 ± 0.364
3.259LysAsn: 3.259 ± 1.728
1.086LysPro: 1.086 ± 1.513
2.716LysGln: 2.716 ± 1.501
2.173LysArg: 2.173 ± 1.145
2.716LysSer: 2.716 ± 0.96
4.345LysThr: 4.345 ± 1.466
1.63LysVal: 1.63 ± 0.671
0.543LysTrp: 0.543 ± 0.364
4.889LysTyr: 4.889 ± 1.328
0.0LysXaa: 0.0 ± 0.0
Leu
5.432LeuAla: 5.432 ± 0.795
2.173LeuCys: 2.173 ± 1.442
4.345LeuAsp: 4.345 ± 1.075
3.259LeuGlu: 3.259 ± 1.02
1.63LeuPhe: 1.63 ± 0.39
4.345LeuGly: 4.345 ± 1.276
1.086LeuHis: 1.086 ± 0.828
2.173LeuIle: 2.173 ± 0.671
2.716LeuLys: 2.716 ± 1.36
5.432LeuLeu: 5.432 ± 1.555
2.173LeuMet: 2.173 ± 0.982
4.345LeuAsn: 4.345 ± 0.856
7.061LeuPro: 7.061 ± 1.082
3.802LeuGln: 3.802 ± 1.964
4.345LeuArg: 4.345 ± 1.266
4.889LeuSer: 4.889 ± 2.601
5.975LeuThr: 5.975 ± 0.859
4.889LeuVal: 4.889 ± 2.263
1.086LeuTrp: 1.086 ± 0.885
2.173LeuTyr: 2.173 ± 0.961
0.0LeuXaa: 0.0 ± 0.0
Met
2.173MetAla: 2.173 ± 1.493
0.543MetCys: 0.543 ± 0.364
1.63MetAsp: 1.63 ± 1.426
0.543MetGlu: 0.543 ± 0.757
1.63MetPhe: 1.63 ± 1.239
0.0MetGly: 0.0 ± 0.0
0.543MetHis: 0.543 ± 0.512
0.0MetIle: 0.0 ± 0.0
2.716MetLys: 2.716 ± 0.745
1.63MetLeu: 1.63 ± 0.896
0.0MetMet: 0.0 ± 0.0
3.259MetAsn: 3.259 ± 1.582
2.173MetPro: 2.173 ± 0.982
2.716MetGln: 2.716 ± 1.501
1.086MetArg: 1.086 ± 0.729
3.802MetSer: 3.802 ± 1.001
0.0MetThr: 0.0 ± 0.0
1.086MetVal: 1.086 ± 0.48
0.543MetTrp: 0.543 ± 0.364
1.63MetTyr: 1.63 ± 0.842
0.0MetXaa: 0.0 ± 0.0
Asn
6.518AsnAla: 6.518 ± 2.553
0.0AsnCys: 0.0 ± 0.0
0.543AsnAsp: 0.543 ± 0.512
2.716AsnGlu: 2.716 ± 1.505
5.975AsnPhe: 5.975 ± 2.167
3.802AsnGly: 3.802 ± 1.396
1.086AsnHis: 1.086 ± 0.48
6.518AsnIle: 6.518 ± 2.374
2.173AsnLys: 2.173 ± 0.686
2.716AsnLeu: 2.716 ± 0.869
2.716AsnMet: 2.716 ± 1.055
4.889AsnAsn: 4.889 ± 1.127
7.605AsnPro: 7.605 ± 1.28
2.716AsnGln: 2.716 ± 1.132
1.086AsnArg: 1.086 ± 0.86
5.432AsnSer: 5.432 ± 1.223
2.173AsnThr: 2.173 ± 0.694
2.716AsnVal: 2.716 ± 1.131
1.086AsnTrp: 1.086 ± 0.506
2.716AsnTyr: 2.716 ± 1.567
0.0AsnXaa: 0.0 ± 0.0
Pro
2.173ProAla: 2.173 ± 0.954
2.173ProCys: 2.173 ± 1.414
4.889ProAsp: 4.889 ± 1.407
2.173ProGlu: 2.173 ± 0.982
2.173ProPhe: 2.173 ± 0.694
2.173ProGly: 2.173 ± 1.348
1.086ProHis: 1.086 ± 1.024
3.259ProIle: 3.259 ± 1.343
2.716ProLys: 2.716 ± 0.972
1.086ProLeu: 1.086 ± 0.828
2.173ProMet: 2.173 ± 0.694
2.173ProAsn: 2.173 ± 1.457
1.086ProPro: 1.086 ± 0.48
3.259ProGln: 3.259 ± 2.117
1.63ProArg: 1.63 ± 0.682
3.259ProSer: 3.259 ± 1.749
2.173ProThr: 2.173 ± 1.053
5.975ProVal: 5.975 ± 1.625
0.543ProTrp: 0.543 ± 0.364
0.543ProTyr: 0.543 ± 0.364
0.0ProXaa: 0.0 ± 0.0
Gln
1.63GlnAla: 1.63 ± 1.08
1.086GlnCys: 1.086 ± 0.48
1.63GlnAsp: 1.63 ± 0.842
1.63GlnGlu: 1.63 ± 0.39
2.173GlnPhe: 2.173 ± 1.683
2.716GlnGly: 2.716 ± 1.279
0.543GlnHis: 0.543 ± 0.512
3.802GlnIle: 3.802 ± 1.34
2.173GlnLys: 2.173 ± 0.81
4.889GlnLeu: 4.889 ± 0.929
1.086GlnMet: 1.086 ± 1.144
2.716GlnAsn: 2.716 ± 1.494
1.086GlnPro: 1.086 ± 0.729
4.345GlnGln: 4.345 ± 1.863
2.716GlnArg: 2.716 ± 1.131
5.975GlnSer: 5.975 ± 2.721
3.259GlnThr: 3.259 ± 1.621
2.716GlnVal: 2.716 ± 1.417
0.543GlnTrp: 0.543 ± 0.512
2.716GlnTyr: 2.716 ± 0.662
0.0GlnXaa: 0.0 ± 0.0
Arg
4.345ArgAla: 4.345 ± 2.447
0.0ArgCys: 0.0 ± 0.0
3.259ArgAsp: 3.259 ± 0.908
1.63ArgGlu: 1.63 ± 0.797
2.716ArgPhe: 2.716 ± 1.132
1.63ArgGly: 1.63 ± 0.83
0.543ArgHis: 0.543 ± 0.512
2.173ArgIle: 2.173 ± 0.961
2.173ArgLys: 2.173 ± 1.229
5.432ArgLeu: 5.432 ± 0.767
1.63ArgMet: 1.63 ± 0.39
3.259ArgAsn: 3.259 ± 0.602
2.716ArgPro: 2.716 ± 0.994
1.63ArgGln: 1.63 ± 0.675
2.173ArgArg: 2.173 ± 1.69
2.173ArgSer: 2.173 ± 0.961
2.716ArgThr: 2.716 ± 1.013
2.716ArgVal: 2.716 ± 1.06
1.086ArgTrp: 1.086 ± 0.48
2.716ArgTyr: 2.716 ± 0.972
0.0ArgXaa: 0.0 ± 0.0
Ser
5.432SerAla: 5.432 ± 2.196
0.543SerCys: 0.543 ± 0.818
4.889SerAsp: 4.889 ± 2.078
5.432SerGlu: 5.432 ± 2.169
3.802SerPhe: 3.802 ± 1.089
2.716SerGly: 2.716 ± 1.024
0.543SerHis: 0.543 ± 0.364
3.802SerIle: 3.802 ± 0.779
4.345SerLys: 4.345 ± 2.394
4.345SerLeu: 4.345 ± 1.593
2.716SerMet: 2.716 ± 1.251
4.345SerAsn: 4.345 ± 1.651
2.173SerPro: 2.173 ± 0.652
3.802SerGln: 3.802 ± 1.549
4.889SerArg: 4.889 ± 1.071
3.259SerSer: 3.259 ± 1.088
2.716SerThr: 2.716 ± 1.458
7.605SerVal: 7.605 ± 1.108
1.086SerTrp: 1.086 ± 1.513
3.802SerTyr: 3.802 ± 1.651
0.0SerXaa: 0.0 ± 0.0
Thr
4.345ThrAla: 4.345 ± 1.197
1.086ThrCys: 1.086 ± 0.833
1.086ThrAsp: 1.086 ± 0.506
2.173ThrGlu: 2.173 ± 1.457
3.802ThrPhe: 3.802 ± 1.16
4.345ThrGly: 4.345 ± 1.526
0.0ThrHis: 0.0 ± 0.0
1.63ThrIle: 1.63 ± 0.931
2.716ThrLys: 2.716 ± 1.357
4.889ThrLeu: 4.889 ± 1.948
1.086ThrMet: 1.086 ± 0.959
3.259ThrAsn: 3.259 ± 1.343
2.716ThrPro: 2.716 ± 1.366
4.889ThrGln: 4.889 ± 1.424
3.259ThrArg: 3.259 ± 0.78
3.259ThrSer: 3.259 ± 1.195
3.802ThrThr: 3.802 ± 1.366
5.432ThrVal: 5.432 ± 2.023
0.0ThrTrp: 0.0 ± 0.0
1.63ThrTyr: 1.63 ± 0.682
0.0ThrXaa: 0.0 ± 0.0
Val
2.716ValAla: 2.716 ± 1.176
0.543ValCys: 0.543 ± 0.364
2.716ValAsp: 2.716 ± 1.366
3.802ValGlu: 3.802 ± 1.549
4.889ValPhe: 4.889 ± 2.406
4.345ValGly: 4.345 ± 2.325
0.543ValHis: 0.543 ± 0.364
3.259ValIle: 3.259 ± 1.364
3.259ValLys: 3.259 ± 0.995
3.802ValLeu: 3.802 ± 1.148
1.63ValMet: 1.63 ± 1.536
5.975ValAsn: 5.975 ± 2.017
4.889ValPro: 4.889 ± 0.758
2.173ValGln: 2.173 ± 1.012
1.63ValArg: 1.63 ± 0.797
5.975ValSer: 5.975 ± 2.476
4.345ValThr: 4.345 ± 1.964
4.889ValVal: 4.889 ± 1.121
0.0ValTrp: 0.0 ± 0.0
2.716ValTyr: 2.716 ± 1.315
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.543TrpCys: 0.543 ± 0.818
0.543TrpAsp: 0.543 ± 0.364
1.63TrpGlu: 1.63 ± 0.83
0.543TrpPhe: 0.543 ± 0.512
0.0TrpGly: 0.0 ± 0.0
0.543TrpHis: 0.543 ± 0.512
0.543TrpIle: 0.543 ± 0.572
0.0TrpLys: 0.0 ± 0.0
1.086TrpLeu: 1.086 ± 0.506
0.0TrpMet: 0.0 ± 0.0
0.543TrpAsn: 0.543 ± 0.512
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.543TrpArg: 0.543 ± 0.512
1.086TrpSer: 1.086 ± 0.48
0.543TrpThr: 0.543 ± 0.757
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.543TrpTyr: 0.543 ± 0.364
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.259TyrAla: 3.259 ± 1.441
1.63TyrCys: 1.63 ± 1.536
2.716TyrAsp: 2.716 ± 0.692
2.716TyrGlu: 2.716 ± 1.132
2.716TyrPhe: 2.716 ± 2.065
4.889TyrGly: 4.889 ± 1.702
1.63TyrHis: 1.63 ± 1.536
3.802TyrIle: 3.802 ± 1.974
3.259TyrLys: 3.259 ± 0.72
2.716TyrLeu: 2.716 ± 0.662
0.543TyrMet: 0.543 ± 0.512
5.432TyrAsn: 5.432 ± 0.858
1.63TyrPro: 1.63 ± 0.682
2.716TyrGln: 2.716 ± 0.692
3.802TyrArg: 3.802 ± 1.589
2.173TyrSer: 2.173 ± 1.23
2.716TyrThr: 2.716 ± 1.122
2.716TyrVal: 2.716 ± 1.122
0.0TyrTrp: 0.0 ± 0.0
3.802TyrTyr: 3.802 ± 1.849
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1842 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski