Amino acid dipepetide frequency for Hubei picorna-like virus 29

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.575AlaAla: 4.575 ± 0.0
2.614AlaCys: 2.614 ± 0.0
2.614AlaAsp: 2.614 ± 0.0
6.863AlaGlu: 6.863 ± 0.0
3.595AlaPhe: 3.595 ± 0.0
4.575AlaGly: 4.575 ± 0.0
2.288AlaHis: 2.288 ± 0.0
4.248AlaIle: 4.248 ± 0.0
2.614AlaLys: 2.614 ± 0.0
4.575AlaLeu: 4.575 ± 0.0
2.288AlaMet: 2.288 ± 0.0
2.614AlaAsn: 2.614 ± 0.0
5.229AlaPro: 5.229 ± 0.0
2.288AlaGln: 2.288 ± 0.0
4.248AlaArg: 4.248 ± 0.0
5.229AlaSer: 5.229 ± 0.0
3.595AlaThr: 3.595 ± 0.0
4.248AlaVal: 4.248 ± 0.0
1.634AlaTrp: 1.634 ± 0.0
2.614AlaTyr: 2.614 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.961CysAla: 1.961 ± 0.0
1.634CysCys: 1.634 ± 0.0
1.634CysAsp: 1.634 ± 0.0
1.634CysGlu: 1.634 ± 0.0
0.654CysPhe: 0.654 ± 0.0
1.961CysGly: 1.961 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.634CysIle: 1.634 ± 0.0
1.634CysLys: 1.634 ± 0.0
2.614CysLeu: 2.614 ± 0.0
0.654CysMet: 0.654 ± 0.0
0.327CysAsn: 0.327 ± 0.0
1.634CysPro: 1.634 ± 0.0
0.654CysGln: 0.654 ± 0.0
1.961CysArg: 1.961 ± 0.0
0.98CysSer: 0.98 ± 0.0
0.654CysThr: 0.654 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.327CysTrp: 0.327 ± 0.0
0.654CysTyr: 0.654 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.922AspAla: 3.922 ± 0.0
0.654AspCys: 0.654 ± 0.0
5.882AspAsp: 5.882 ± 0.0
2.941AspGlu: 2.941 ± 0.0
4.248AspPhe: 4.248 ± 0.0
3.595AspGly: 3.595 ± 0.0
1.634AspHis: 1.634 ± 0.0
3.268AspIle: 3.268 ± 0.0
3.595AspLys: 3.595 ± 0.0
5.882AspLeu: 5.882 ± 0.0
1.634AspMet: 1.634 ± 0.0
0.654AspAsn: 0.654 ± 0.0
2.614AspPro: 2.614 ± 0.0
1.307AspGln: 1.307 ± 0.0
4.248AspArg: 4.248 ± 0.0
4.248AspSer: 4.248 ± 0.0
2.288AspThr: 2.288 ± 0.0
4.248AspVal: 4.248 ± 0.0
0.98AspTrp: 0.98 ± 0.0
3.595AspTyr: 3.595 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
4.902GluAla: 4.902 ± 0.0
1.634GluCys: 1.634 ± 0.0
2.941GluAsp: 2.941 ± 0.0
6.209GluGlu: 6.209 ± 0.0
2.614GluPhe: 2.614 ± 0.0
4.575GluGly: 4.575 ± 0.0
2.614GluHis: 2.614 ± 0.0
1.961GluIle: 1.961 ± 0.0
2.288GluLys: 2.288 ± 0.0
5.229GluLeu: 5.229 ± 0.0
1.307GluMet: 1.307 ± 0.0
0.98GluAsn: 0.98 ± 0.0
2.941GluPro: 2.941 ± 0.0
1.961GluGln: 1.961 ± 0.0
2.614GluArg: 2.614 ± 0.0
1.307GluSer: 1.307 ± 0.0
3.268GluThr: 3.268 ± 0.0
4.902GluVal: 4.902 ± 0.0
1.961GluTrp: 1.961 ± 0.0
0.98GluTyr: 0.98 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
3.595PheAla: 3.595 ± 0.0
0.327PheCys: 0.327 ± 0.0
3.922PheAsp: 3.922 ± 0.0
1.634PheGlu: 1.634 ± 0.0
4.248PhePhe: 4.248 ± 0.0
3.922PheGly: 3.922 ± 0.0
0.0PheHis: 0.0 ± 0.0
2.288PheIle: 2.288 ± 0.0
4.248PheLys: 4.248 ± 0.0
4.248PheLeu: 4.248 ± 0.0
0.98PheMet: 0.98 ± 0.0
1.634PheAsn: 1.634 ± 0.0
2.614PhePro: 2.614 ± 0.0
1.634PheGln: 1.634 ± 0.0
4.248PheArg: 4.248 ± 0.0
4.902PheSer: 4.902 ± 0.0
2.288PheThr: 2.288 ± 0.0
4.248PheVal: 4.248 ± 0.0
0.327PheTrp: 0.327 ± 0.0
2.614PheTyr: 2.614 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.902GlyAla: 4.902 ± 0.0
1.307GlyCys: 1.307 ± 0.0
5.229GlyAsp: 5.229 ± 0.0
3.922GlyGlu: 3.922 ± 0.0
2.288GlyPhe: 2.288 ± 0.0
1.634GlyGly: 1.634 ± 0.0
1.307GlyHis: 1.307 ± 0.0
3.922GlyIle: 3.922 ± 0.0
3.595GlyLys: 3.595 ± 0.0
4.902GlyLeu: 4.902 ± 0.0
1.634GlyMet: 1.634 ± 0.0
1.961GlyAsn: 1.961 ± 0.0
1.634GlyPro: 1.634 ± 0.0
1.961GlyGln: 1.961 ± 0.0
1.634GlyArg: 1.634 ± 0.0
7.516GlySer: 7.516 ± 0.0
1.961GlyThr: 1.961 ± 0.0
2.614GlyVal: 2.614 ± 0.0
0.327GlyTrp: 0.327 ± 0.0
1.634GlyTyr: 1.634 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.634HisAla: 1.634 ± 0.0
0.654HisCys: 0.654 ± 0.0
0.98HisAsp: 0.98 ± 0.0
1.634HisGlu: 1.634 ± 0.0
1.307HisPhe: 1.307 ± 0.0
2.614HisGly: 2.614 ± 0.0
0.98HisHis: 0.98 ± 0.0
1.307HisIle: 1.307 ± 0.0
0.327HisLys: 0.327 ± 0.0
2.614HisLeu: 2.614 ± 0.0
0.654HisMet: 0.654 ± 0.0
0.327HisAsn: 0.327 ± 0.0
1.307HisPro: 1.307 ± 0.0
0.98HisGln: 0.98 ± 0.0
0.98HisArg: 0.98 ± 0.0
0.98HisSer: 0.98 ± 0.0
2.288HisThr: 2.288 ± 0.0
0.98HisVal: 0.98 ± 0.0
0.327HisTrp: 0.327 ± 0.0
0.327HisTyr: 0.327 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
6.209IleAla: 6.209 ± 0.0
1.634IleCys: 1.634 ± 0.0
3.268IleAsp: 3.268 ± 0.0
0.98IleGlu: 0.98 ± 0.0
4.248IlePhe: 4.248 ± 0.0
2.941IleGly: 2.941 ± 0.0
0.0IleHis: 0.0 ± 0.0
2.941IleIle: 2.941 ± 0.0
3.268IleLys: 3.268 ± 0.0
2.288IleLeu: 2.288 ± 0.0
0.98IleMet: 0.98 ± 0.0
3.595IleAsn: 3.595 ± 0.0
4.575IlePro: 4.575 ± 0.0
0.654IleGln: 0.654 ± 0.0
1.961IleArg: 1.961 ± 0.0
5.556IleSer: 5.556 ± 0.0
2.614IleThr: 2.614 ± 0.0
3.595IleVal: 3.595 ± 0.0
1.634IleTrp: 1.634 ± 0.0
1.634IleTyr: 1.634 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
1.961LysAla: 1.961 ± 0.0
1.307LysCys: 1.307 ± 0.0
5.229LysAsp: 5.229 ± 0.0
4.248LysGlu: 4.248 ± 0.0
2.288LysPhe: 2.288 ± 0.0
3.268LysGly: 3.268 ± 0.0
0.98LysHis: 0.98 ± 0.0
2.614LysIle: 2.614 ± 0.0
3.595LysLys: 3.595 ± 0.0
5.229LysLeu: 5.229 ± 0.0
0.654LysMet: 0.654 ± 0.0
2.288LysAsn: 2.288 ± 0.0
3.595LysPro: 3.595 ± 0.0
1.634LysGln: 1.634 ± 0.0
3.922LysArg: 3.922 ± 0.0
2.941LysSer: 2.941 ± 0.0
2.614LysThr: 2.614 ± 0.0
2.614LysVal: 2.614 ± 0.0
0.654LysTrp: 0.654 ± 0.0
4.248LysTyr: 4.248 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
5.882LeuAla: 5.882 ± 0.0
1.961LeuCys: 1.961 ± 0.0
5.882LeuAsp: 5.882 ± 0.0
4.902LeuGlu: 4.902 ± 0.0
5.229LeuPhe: 5.229 ± 0.0
4.575LeuGly: 4.575 ± 0.0
1.961LeuHis: 1.961 ± 0.0
3.268LeuIle: 3.268 ± 0.0
8.17LeuLys: 8.17 ± 0.0
7.516LeuLeu: 7.516 ± 0.0
0.98LeuMet: 0.98 ± 0.0
3.922LeuAsn: 3.922 ± 0.0
3.922LeuPro: 3.922 ± 0.0
3.268LeuGln: 3.268 ± 0.0
5.556LeuArg: 5.556 ± 0.0
6.536LeuSer: 6.536 ± 0.0
4.902LeuThr: 4.902 ± 0.0
5.882LeuVal: 5.882 ± 0.0
1.307LeuTrp: 1.307 ± 0.0
3.922LeuTyr: 3.922 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
3.268MetAla: 3.268 ± 0.0
0.654MetCys: 0.654 ± 0.0
2.288MetAsp: 2.288 ± 0.0
1.307MetGlu: 1.307 ± 0.0
0.98MetPhe: 0.98 ± 0.0
0.98MetGly: 0.98 ± 0.0
1.307MetHis: 1.307 ± 0.0
0.654MetIle: 0.654 ± 0.0
0.327MetLys: 0.327 ± 0.0
2.288MetLeu: 2.288 ± 0.0
1.307MetMet: 1.307 ± 0.0
0.98MetAsn: 0.98 ± 0.0
1.634MetPro: 1.634 ± 0.0
0.654MetGln: 0.654 ± 0.0
1.634MetArg: 1.634 ± 0.0
2.288MetSer: 2.288 ± 0.0
0.327MetThr: 0.327 ± 0.0
1.634MetVal: 1.634 ± 0.0
0.0MetTrp: 0.0 ± 0.0
1.634MetTyr: 1.634 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.614AsnAla: 2.614 ± 0.0
0.98AsnCys: 0.98 ± 0.0
0.654AsnAsp: 0.654 ± 0.0
1.961AsnGlu: 1.961 ± 0.0
1.961AsnPhe: 1.961 ± 0.0
1.307AsnGly: 1.307 ± 0.0
0.654AsnHis: 0.654 ± 0.0
1.961AsnIle: 1.961 ± 0.0
1.307AsnLys: 1.307 ± 0.0
1.961AsnLeu: 1.961 ± 0.0
1.961AsnMet: 1.961 ± 0.0
1.307AsnAsn: 1.307 ± 0.0
1.307AsnPro: 1.307 ± 0.0
0.654AsnGln: 0.654 ± 0.0
2.614AsnArg: 2.614 ± 0.0
2.941AsnSer: 2.941 ± 0.0
2.288AsnThr: 2.288 ± 0.0
2.941AsnVal: 2.941 ± 0.0
0.327AsnTrp: 0.327 ± 0.0
1.961AsnTyr: 1.961 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
2.288ProAla: 2.288 ± 0.0
0.98ProCys: 0.98 ± 0.0
1.307ProAsp: 1.307 ± 0.0
2.941ProGlu: 2.941 ± 0.0
1.961ProPhe: 1.961 ± 0.0
2.614ProGly: 2.614 ± 0.0
1.961ProHis: 1.961 ± 0.0
4.248ProIle: 4.248 ± 0.0
1.634ProLys: 1.634 ± 0.0
6.536ProLeu: 6.536 ± 0.0
0.98ProMet: 0.98 ± 0.0
1.634ProAsn: 1.634 ± 0.0
2.288ProPro: 2.288 ± 0.0
4.575ProGln: 4.575 ± 0.0
1.307ProArg: 1.307 ± 0.0
2.614ProSer: 2.614 ± 0.0
4.248ProThr: 4.248 ± 0.0
4.575ProVal: 4.575 ± 0.0
0.327ProTrp: 0.327 ± 0.0
2.614ProTyr: 2.614 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.614GlnAla: 2.614 ± 0.0
0.0GlnCys: 0.0 ± 0.0
0.98GlnAsp: 0.98 ± 0.0
0.98GlnGlu: 0.98 ± 0.0
1.634GlnPhe: 1.634 ± 0.0
2.614GlnGly: 2.614 ± 0.0
1.634GlnHis: 1.634 ± 0.0
2.614GlnIle: 2.614 ± 0.0
0.98GlnLys: 0.98 ± 0.0
2.941GlnLeu: 2.941 ± 0.0
2.288GlnMet: 2.288 ± 0.0
1.307GlnAsn: 1.307 ± 0.0
2.288GlnPro: 2.288 ± 0.0
2.288GlnGln: 2.288 ± 0.0
2.614GlnArg: 2.614 ± 0.0
2.941GlnSer: 2.941 ± 0.0
0.98GlnThr: 0.98 ± 0.0
2.941GlnVal: 2.941 ± 0.0
0.327GlnTrp: 0.327 ± 0.0
0.98GlnTyr: 0.98 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.595ArgAla: 3.595 ± 0.0
0.327ArgCys: 0.327 ± 0.0
1.961ArgAsp: 1.961 ± 0.0
4.248ArgGlu: 4.248 ± 0.0
3.595ArgPhe: 3.595 ± 0.0
1.307ArgGly: 1.307 ± 0.0
1.307ArgHis: 1.307 ± 0.0
3.595ArgIle: 3.595 ± 0.0
2.288ArgLys: 2.288 ± 0.0
5.556ArgLeu: 5.556 ± 0.0
1.961ArgMet: 1.961 ± 0.0
1.307ArgAsn: 1.307 ± 0.0
3.595ArgPro: 3.595 ± 0.0
2.288ArgGln: 2.288 ± 0.0
3.922ArgArg: 3.922 ± 0.0
2.288ArgSer: 2.288 ± 0.0
3.268ArgThr: 3.268 ± 0.0
3.595ArgVal: 3.595 ± 0.0
1.307ArgTrp: 1.307 ± 0.0
2.941ArgTyr: 2.941 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
4.575SerAla: 4.575 ± 0.0
0.98SerCys: 0.98 ± 0.0
3.595SerAsp: 3.595 ± 0.0
3.595SerGlu: 3.595 ± 0.0
4.575SerPhe: 4.575 ± 0.0
3.922SerGly: 3.922 ± 0.0
0.98SerHis: 0.98 ± 0.0
5.882SerIle: 5.882 ± 0.0
4.902SerLys: 4.902 ± 0.0
7.843SerLeu: 7.843 ± 0.0
1.634SerMet: 1.634 ± 0.0
3.268SerAsn: 3.268 ± 0.0
3.268SerPro: 3.268 ± 0.0
3.595SerGln: 3.595 ± 0.0
2.288SerArg: 2.288 ± 0.0
5.229SerSer: 5.229 ± 0.0
1.961SerThr: 1.961 ± 0.0
7.19SerVal: 7.19 ± 0.0
0.98SerTrp: 0.98 ± 0.0
1.961SerTyr: 1.961 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
2.614ThrAla: 2.614 ± 0.0
1.634ThrCys: 1.634 ± 0.0
4.902ThrAsp: 4.902 ± 0.0
1.634ThrGlu: 1.634 ± 0.0
3.268ThrPhe: 3.268 ± 0.0
3.595ThrGly: 3.595 ± 0.0
0.98ThrHis: 0.98 ± 0.0
2.288ThrIle: 2.288 ± 0.0
2.614ThrLys: 2.614 ± 0.0
3.595ThrLeu: 3.595 ± 0.0
1.307ThrMet: 1.307 ± 0.0
1.307ThrAsn: 1.307 ± 0.0
1.634ThrPro: 1.634 ± 0.0
0.98ThrGln: 0.98 ± 0.0
1.961ThrArg: 1.961 ± 0.0
5.229ThrSer: 5.229 ± 0.0
3.595ThrThr: 3.595 ± 0.0
4.248ThrVal: 4.248 ± 0.0
0.327ThrTrp: 0.327 ± 0.0
2.941ThrTyr: 2.941 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
7.843ValAla: 7.843 ± 0.0
1.307ValCys: 1.307 ± 0.0
4.575ValAsp: 4.575 ± 0.0
3.268ValGlu: 3.268 ± 0.0
1.634ValPhe: 1.634 ± 0.0
2.614ValGly: 2.614 ± 0.0
1.307ValHis: 1.307 ± 0.0
4.248ValIle: 4.248 ± 0.0
6.536ValLys: 6.536 ± 0.0
8.497ValLeu: 8.497 ± 0.0
1.961ValMet: 1.961 ± 0.0
3.268ValAsn: 3.268 ± 0.0
2.614ValPro: 2.614 ± 0.0
2.614ValGln: 2.614 ± 0.0
3.595ValArg: 3.595 ± 0.0
4.575ValSer: 4.575 ± 0.0
1.961ValThr: 1.961 ± 0.0
4.575ValVal: 4.575 ± 0.0
0.654ValTrp: 0.654 ± 0.0
2.614ValTyr: 2.614 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.654TrpAla: 0.654 ± 0.0
1.634TrpCys: 1.634 ± 0.0
0.98TrpAsp: 0.98 ± 0.0
0.327TrpGlu: 0.327 ± 0.0
0.654TrpPhe: 0.654 ± 0.0
1.307TrpGly: 1.307 ± 0.0
0.327TrpHis: 0.327 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
2.288TrpLeu: 2.288 ± 0.0
0.327TrpMet: 0.327 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.327TrpPro: 0.327 ± 0.0
0.654TrpGln: 0.654 ± 0.0
1.307TrpArg: 1.307 ± 0.0
1.307TrpSer: 1.307 ± 0.0
1.307TrpThr: 1.307 ± 0.0
0.654TrpVal: 0.654 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.307TrpTyr: 1.307 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.941TyrAla: 2.941 ± 0.0
0.98TyrCys: 0.98 ± 0.0
2.614TyrAsp: 2.614 ± 0.0
1.961TyrGlu: 1.961 ± 0.0
3.268TyrPhe: 3.268 ± 0.0
1.961TyrGly: 1.961 ± 0.0
0.98TyrHis: 0.98 ± 0.0
1.634TyrIle: 1.634 ± 0.0
1.961TyrLys: 1.961 ± 0.0
2.941TyrLeu: 2.941 ± 0.0
0.327TyrMet: 0.327 ± 0.0
0.98TyrAsn: 0.98 ± 0.0
2.614TyrPro: 2.614 ± 0.0
1.307TyrGln: 1.307 ± 0.0
1.634TyrArg: 1.634 ± 0.0
2.614TyrSer: 2.614 ± 0.0
4.248TyrThr: 4.248 ± 0.0
4.575TyrVal: 4.575 ± 0.0
1.634TyrTrp: 1.634 ± 0.0
1.307TyrTyr: 1.307 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (3061 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski