Amino acid dipepetide frequency for Carnobacterium divergens DSM 20623

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.205AlaAla: 5.205 ± 0.112
0.448AlaCys: 0.448 ± 0.021
3.464AlaAsp: 3.464 ± 0.073
4.425AlaGlu: 4.425 ± 0.082
3.149AlaPhe: 3.149 ± 0.068
5.091AlaGly: 5.091 ± 0.102
1.088AlaHis: 1.088 ± 0.035
6.091AlaIle: 6.091 ± 0.092
5.404AlaLys: 5.404 ± 0.083
7.031AlaLeu: 7.031 ± 0.123
1.938AlaMet: 1.938 ± 0.053
3.182AlaAsn: 3.182 ± 0.062
2.14AlaPro: 2.14 ± 0.055
2.069AlaGln: 2.069 ± 0.055
2.177AlaArg: 2.177 ± 0.058
4.336AlaSer: 4.336 ± 0.081
4.746AlaThr: 4.746 ± 0.081
4.961AlaVal: 4.961 ± 0.095
0.503AlaTrp: 0.503 ± 0.028
2.34AlaTyr: 2.34 ± 0.057
0.0AlaXaa: 0.0 ± 0.0
Cys
0.3CysAla: 0.3 ± 0.02
0.056CysCys: 0.056 ± 0.009
0.28CysAsp: 0.28 ± 0.02
0.338CysGlu: 0.338 ± 0.022
0.321CysPhe: 0.321 ± 0.022
0.516CysGly: 0.516 ± 0.027
0.146CysHis: 0.146 ± 0.014
0.417CysIle: 0.417 ± 0.021
0.239CysLys: 0.239 ± 0.019
0.631CysLeu: 0.631 ± 0.031
0.133CysMet: 0.133 ± 0.014
0.22CysAsn: 0.22 ± 0.017
0.215CysPro: 0.215 ± 0.018
0.255CysGln: 0.255 ± 0.019
0.174CysArg: 0.174 ± 0.016
0.407CysSer: 0.407 ± 0.021
0.281CysThr: 0.281 ± 0.019
0.374CysVal: 0.374 ± 0.022
0.053CysTrp: 0.053 ± 0.008
0.248CysTyr: 0.248 ± 0.02
0.0CysXaa: 0.0 ± 0.0
Asp
3.53AspAla: 3.53 ± 0.074
0.293AspCys: 0.293 ± 0.022
2.279AspAsp: 2.279 ± 0.08
4.173AspGlu: 4.173 ± 0.088
2.774AspPhe: 2.774 ± 0.062
3.527AspGly: 3.527 ± 0.082
0.947AspHis: 0.947 ± 0.035
3.862AspIle: 3.862 ± 0.073
3.365AspLys: 3.365 ± 0.078
5.046AspLeu: 5.046 ± 0.079
1.231AspMet: 1.231 ± 0.042
2.165AspAsn: 2.165 ± 0.055
1.925AspPro: 1.925 ± 0.062
1.979AspGln: 1.979 ± 0.052
1.723AspArg: 1.723 ± 0.055
3.127AspSer: 3.127 ± 0.073
2.906AspThr: 2.906 ± 0.067
3.599AspVal: 3.599 ± 0.07
0.525AspTrp: 0.525 ± 0.028
2.382AspTyr: 2.382 ± 0.053
0.0AspXaa: 0.0 ± 0.0
Glu
5.647GluAla: 5.647 ± 0.103
0.3GluCys: 0.3 ± 0.023
3.51GluAsp: 3.51 ± 0.064
6.314GluGlu: 6.314 ± 0.128
2.741GluPhe: 2.741 ± 0.06
3.806GluGly: 3.806 ± 0.076
1.129GluHis: 1.129 ± 0.04
5.794GluIle: 5.794 ± 0.098
6.812GluLys: 6.812 ± 0.119
7.531GluLeu: 7.531 ± 0.124
2.329GluMet: 2.329 ± 0.052
4.191GluAsn: 4.191 ± 0.084
1.908GluPro: 1.908 ± 0.057
2.889GluGln: 2.889 ± 0.072
2.766GluArg: 2.766 ± 0.065
3.685GluSer: 3.685 ± 0.076
4.598GluThr: 4.598 ± 0.089
5.059GluVal: 5.059 ± 0.098
0.654GluTrp: 0.654 ± 0.031
1.957GluTyr: 1.957 ± 0.054
0.0GluXaa: 0.0 ± 0.0
Phe
2.665PheAla: 2.665 ± 0.065
0.326PheCys: 0.326 ± 0.019
2.625PheAsp: 2.625 ± 0.052
2.811PheGlu: 2.811 ± 0.062
2.429PhePhe: 2.429 ± 0.083
3.186PheGly: 3.186 ± 0.079
0.824PheHis: 0.824 ± 0.034
3.741PheIle: 3.741 ± 0.099
2.983PheLys: 2.983 ± 0.062
4.42PheLeu: 4.42 ± 0.098
1.1PheMet: 1.1 ± 0.036
2.313PheAsn: 2.313 ± 0.053
1.597PhePro: 1.597 ± 0.052
1.601PheGln: 1.601 ± 0.054
1.171PheArg: 1.171 ± 0.041
3.514PheSer: 3.514 ± 0.083
2.538PheThr: 2.538 ± 0.056
3.136PheVal: 3.136 ± 0.068
0.43PheTrp: 0.43 ± 0.025
1.889PheTyr: 1.889 ± 0.058
0.0PheXaa: 0.0 ± 0.0
Gly
4.677GlyAla: 4.677 ± 0.101
0.438GlyCys: 0.438 ± 0.025
3.198GlyAsp: 3.198 ± 0.079
4.437GlyGlu: 4.437 ± 0.081
3.239GlyPhe: 3.239 ± 0.068
4.631GlyGly: 4.631 ± 0.117
1.12GlyHis: 1.12 ± 0.043
5.927GlyIle: 5.927 ± 0.115
4.917GlyLys: 4.917 ± 0.078
6.309GlyLeu: 6.309 ± 0.102
2.004GlyMet: 2.004 ± 0.05
3.01GlyAsn: 3.01 ± 0.066
1.401GlyPro: 1.401 ± 0.048
2.116GlyGln: 2.116 ± 0.062
2.141GlyArg: 2.141 ± 0.063
3.948GlySer: 3.948 ± 0.077
4.421GlyThr: 4.421 ± 0.088
4.794GlyVal: 4.794 ± 0.088
0.663GlyTrp: 0.663 ± 0.031
2.572GlyTyr: 2.572 ± 0.059
0.001GlyXaa: 0.001 ± 0.001
His
0.986HisAla: 0.986 ± 0.034
0.135HisCys: 0.135 ± 0.013
0.842HisAsp: 0.842 ± 0.035
1.165HisGlu: 1.165 ± 0.04
1.019HisPhe: 1.019 ± 0.04
1.137HisGly: 1.137 ± 0.04
0.54HisHis: 0.54 ± 0.028
1.15HisIle: 1.15 ± 0.046
0.818HisLys: 0.818 ± 0.031
2.055HisLeu: 2.055 ± 0.06
0.424HisMet: 0.424 ± 0.024
0.601HisAsn: 0.601 ± 0.027
0.869HisPro: 0.869 ± 0.036
0.906HisGln: 0.906 ± 0.035
0.675HisArg: 0.675 ± 0.033
1.023HisSer: 1.023 ± 0.033
0.886HisThr: 0.886 ± 0.036
1.128HisVal: 1.128 ± 0.038
0.161HisTrp: 0.161 ± 0.014
0.991HisTyr: 0.991 ± 0.038
0.0HisXaa: 0.0 ± 0.0
Ile
6.069IleAla: 6.069 ± 0.114
0.613IleCys: 0.613 ± 0.029
4.608IleAsp: 4.608 ± 0.094
6.0IleGlu: 6.0 ± 0.098
3.392IlePhe: 3.392 ± 0.089
5.829IleGly: 5.829 ± 0.11
1.532IleHis: 1.532 ± 0.047
5.542IleIle: 5.542 ± 0.1
5.143IleLys: 5.143 ± 0.085
7.406IleLeu: 7.406 ± 0.123
1.721IleMet: 1.721 ± 0.053
3.51IleAsn: 3.51 ± 0.08
3.267IlePro: 3.267 ± 0.065
3.312IleGln: 3.312 ± 0.077
2.621IleArg: 2.621 ± 0.053
5.2IleSer: 5.2 ± 0.085
4.534IleThr: 4.534 ± 0.082
5.615IleVal: 5.615 ± 0.105
0.578IleTrp: 0.578 ± 0.029
2.486IleTyr: 2.486 ± 0.059
0.0IleXaa: 0.0 ± 0.0
Lys
5.078LysAla: 5.078 ± 0.1
0.222LysCys: 0.222 ± 0.019
3.988LysAsp: 3.988 ± 0.097
7.675LysGlu: 7.675 ± 0.118
1.959LysPhe: 1.959 ± 0.055
4.331LysGly: 4.331 ± 0.085
0.979LysHis: 0.979 ± 0.038
5.745LysIle: 5.745 ± 0.095
7.36LysLys: 7.36 ± 0.118
6.192LysLeu: 6.192 ± 0.086
2.624LysMet: 2.624 ± 0.062
4.439LysAsn: 4.439 ± 0.081
2.099LysPro: 2.099 ± 0.067
3.21LysGln: 3.21 ± 0.064
2.957LysArg: 2.957 ± 0.074
3.718LysSer: 3.718 ± 0.076
4.306LysThr: 4.306 ± 0.064
4.648LysVal: 4.648 ± 0.085
0.681LysTrp: 0.681 ± 0.032
2.109LysTyr: 2.109 ± 0.053
0.0LysXaa: 0.0 ± 0.0
Leu
7.618LeuAla: 7.618 ± 0.114
0.537LeuCys: 0.537 ± 0.028
4.939LeuAsp: 4.939 ± 0.086
6.558LeuGlu: 6.558 ± 0.101
4.813LeuPhe: 4.813 ± 0.116
6.038LeuGly: 6.038 ± 0.102
1.514LeuHis: 1.514 ± 0.044
7.724LeuIle: 7.724 ± 0.152
7.445LeuLys: 7.445 ± 0.104
9.99LeuLeu: 9.99 ± 0.167
2.741LeuMet: 2.741 ± 0.059
4.973LeuAsn: 4.973 ± 0.084
3.786LeuPro: 3.786 ± 0.072
3.149LeuGln: 3.149 ± 0.074
2.966LeuArg: 2.966 ± 0.067
6.808LeuSer: 6.808 ± 0.102
6.858LeuThr: 6.858 ± 0.111
6.809LeuVal: 6.809 ± 0.115
0.661LeuTrp: 0.661 ± 0.035
3.031LeuTyr: 3.031 ± 0.076
0.0LeuXaa: 0.0 ± 0.0
Met
1.926MetAla: 1.926 ± 0.055
0.106MetCys: 0.106 ± 0.013
1.422MetAsp: 1.422 ± 0.038
1.926MetGlu: 1.926 ± 0.057
0.841MetPhe: 0.841 ± 0.035
1.844MetGly: 1.844 ± 0.058
0.374MetHis: 0.374 ± 0.024
2.296MetIle: 2.296 ± 0.065
2.368MetLys: 2.368 ± 0.044
2.424MetLeu: 2.424 ± 0.067
0.959MetMet: 0.959 ± 0.04
1.625MetAsn: 1.625 ± 0.046
0.915MetPro: 0.915 ± 0.035
0.877MetGln: 0.877 ± 0.033
0.939MetArg: 0.939 ± 0.036
1.641MetSer: 1.641 ± 0.046
1.791MetThr: 1.791 ± 0.047
1.847MetVal: 1.847 ± 0.057
0.171MetTrp: 0.171 ± 0.017
0.715MetTyr: 0.715 ± 0.03
0.0MetXaa: 0.0 ± 0.0
Asn
2.912AsnAla: 2.912 ± 0.069
0.276AsnCys: 0.276 ± 0.018
2.438AsnAsp: 2.438 ± 0.061
3.945AsnGlu: 3.945 ± 0.083
2.002AsnPhe: 2.002 ± 0.057
3.671AsnGly: 3.671 ± 0.078
1.15AsnHis: 1.15 ± 0.045
2.985AsnIle: 2.985 ± 0.06
3.318AsnLys: 3.318 ± 0.073
4.374AsnLeu: 4.374 ± 0.068
1.239AsnMet: 1.239 ± 0.045
2.238AsnAsn: 2.238 ± 0.071
2.264AsnPro: 2.264 ± 0.055
3.119AsnGln: 3.119 ± 0.075
1.874AsnArg: 1.874 ± 0.053
2.796AsnSer: 2.796 ± 0.059
2.462AsnThr: 2.462 ± 0.069
3.013AsnVal: 3.013 ± 0.066
0.584AsnTrp: 0.584 ± 0.029
2.05AsnTyr: 2.05 ± 0.055
0.0AsnXaa: 0.0 ± 0.0
Pro
2.325ProAla: 2.325 ± 0.066
0.143ProCys: 0.143 ± 0.014
1.833ProAsp: 1.833 ± 0.048
2.783ProGlu: 2.783 ± 0.068
1.821ProPhe: 1.821 ± 0.051
1.876ProGly: 1.876 ± 0.056
0.659ProHis: 0.659 ± 0.031
2.978ProIle: 2.978 ± 0.061
2.351ProLys: 2.351 ± 0.058
3.328ProLeu: 3.328 ± 0.069
0.812ProMet: 0.812 ± 0.038
1.718ProAsn: 1.718 ± 0.052
0.801ProPro: 0.801 ± 0.034
1.138ProGln: 1.138 ± 0.037
0.848ProArg: 0.848 ± 0.036
2.057ProSer: 2.057 ± 0.058
2.552ProThr: 2.552 ± 0.066
2.627ProVal: 2.627 ± 0.074
0.255ProTrp: 0.255 ± 0.016
1.287ProTyr: 1.287 ± 0.046
0.001ProXaa: 0.001 ± 0.001
Gln
2.77GlnAla: 2.77 ± 0.06
0.145GlnCys: 0.145 ± 0.013
1.61GlnAsp: 1.61 ± 0.047
2.938GlnGlu: 2.938 ± 0.067
1.848GlnPhe: 1.848 ± 0.056
2.043GlnGly: 2.043 ± 0.057
0.681GlnHis: 0.681 ± 0.032
2.786GlnIle: 2.786 ± 0.064
3.269GlnLys: 3.269 ± 0.079
4.817GlnLeu: 4.817 ± 0.099
1.036GlnMet: 1.036 ± 0.036
1.865GlnAsn: 1.865 ± 0.055
1.25GlnPro: 1.25 ± 0.041
2.043GlnGln: 2.043 ± 0.066
1.283GlnArg: 1.283 ± 0.044
2.002GlnSer: 2.002 ± 0.054
2.491GlnThr: 2.491 ± 0.061
2.818GlnVal: 2.818 ± 0.066
0.361GlnTrp: 0.361 ± 0.021
1.17GlnTyr: 1.17 ± 0.041
0.0GlnXaa: 0.0 ± 0.0
Arg
1.869ArgAla: 1.869 ± 0.063
0.182ArgCys: 0.182 ± 0.017
1.576ArgAsp: 1.576 ± 0.046
2.323ArgGlu: 2.323 ± 0.05
1.71ArgPhe: 1.71 ± 0.051
2.061ArgGly: 2.061 ± 0.058
0.631ArgHis: 0.631 ± 0.028
2.808ArgIle: 2.808 ± 0.066
2.68ArgLys: 2.68 ± 0.062
3.387ArgLeu: 3.387 ± 0.077
1.059ArgMet: 1.059 ± 0.037
1.633ArgAsn: 1.633 ± 0.052
1.041ArgPro: 1.041 ± 0.037
1.293ArgGln: 1.293 ± 0.042
1.378ArgArg: 1.378 ± 0.051
1.831ArgSer: 1.831 ± 0.053
1.722ArgThr: 1.722 ± 0.048
2.25ArgVal: 2.25 ± 0.057
0.271ArgTrp: 0.271 ± 0.02
1.459ArgTyr: 1.459 ± 0.046
0.0ArgXaa: 0.0 ± 0.0
Ser
3.759SerAla: 3.759 ± 0.09
0.309SerCys: 0.309 ± 0.021
3.184SerAsp: 3.184 ± 0.065
4.141SerGlu: 4.141 ± 0.072
3.218SerPhe: 3.218 ± 0.073
4.273SerGly: 4.273 ± 0.08
1.059SerHis: 1.059 ± 0.037
5.286SerIle: 5.286 ± 0.102
4.291SerLys: 4.291 ± 0.065
6.172SerLeu: 6.172 ± 0.1
1.483SerMet: 1.483 ± 0.044
2.95SerAsn: 2.95 ± 0.078
1.878SerPro: 1.878 ± 0.05
2.259SerGln: 2.259 ± 0.054
1.9SerArg: 1.9 ± 0.046
3.96SerSer: 3.96 ± 0.103
3.576SerThr: 3.576 ± 0.083
4.167SerVal: 4.167 ± 0.077
0.604SerTrp: 0.604 ± 0.028
2.542SerTyr: 2.542 ± 0.063
0.0SerXaa: 0.0 ± 0.0
Thr
4.346ThrAla: 4.346 ± 0.08
0.284ThrCys: 0.284 ± 0.02
3.344ThrAsp: 3.344 ± 0.085
3.981ThrGlu: 3.981 ± 0.082
2.727ThrPhe: 2.727 ± 0.075
4.504ThrGly: 4.504 ± 0.092
1.055ThrHis: 1.055 ± 0.041
5.614ThrIle: 5.614 ± 0.1
4.55ThrLys: 4.55 ± 0.075
6.072ThrLeu: 6.072 ± 0.094
1.384ThrMet: 1.384 ± 0.045
3.088ThrAsn: 3.088 ± 0.07
2.585ThrPro: 2.585 ± 0.069
1.967ThrGln: 1.967 ± 0.056
1.702ThrArg: 1.702 ± 0.045
3.604ThrSer: 3.604 ± 0.066
4.159ThrThr: 4.159 ± 0.096
4.61ThrVal: 4.61 ± 0.089
0.479ThrTrp: 0.479 ± 0.028
2.026ThrTyr: 2.026 ± 0.051
0.0ThrXaa: 0.0 ± 0.0
Val
5.578ValAla: 5.578 ± 0.094
0.512ValCys: 0.512 ± 0.027
3.879ValAsp: 3.879 ± 0.084
4.842ValGlu: 4.842 ± 0.083
2.807ValPhe: 2.807 ± 0.064
4.773ValGly: 4.773 ± 0.086
1.076ValHis: 1.076 ± 0.044
5.416ValIle: 5.416 ± 0.089
4.586ValLys: 4.586 ± 0.088
6.647ValLeu: 6.647 ± 0.103
1.849ValMet: 1.849 ± 0.048
2.991ValAsn: 2.991 ± 0.068
2.668ValPro: 2.668 ± 0.064
2.166ValGln: 2.166 ± 0.059
2.014ValArg: 2.014 ± 0.056
4.62ValSer: 4.62 ± 0.084
4.891ValThr: 4.891 ± 0.094
5.285ValVal: 5.285 ± 0.1
0.503ValTrp: 0.503 ± 0.027
2.198ValTyr: 2.198 ± 0.053
0.0ValXaa: 0.0 ± 0.0
Trp
0.466TrpAla: 0.466 ± 0.024
0.053TrpCys: 0.053 ± 0.008
0.458TrpAsp: 0.458 ± 0.027
0.553TrpGlu: 0.553 ± 0.032
0.418TrpPhe: 0.418 ± 0.028
0.551TrpGly: 0.551 ± 0.03
0.184TrpHis: 0.184 ± 0.017
0.695TrpIle: 0.695 ± 0.032
0.606TrpLys: 0.606 ± 0.03
0.984TrpLeu: 0.984 ± 0.044
0.233TrpMet: 0.233 ± 0.017
0.537TrpAsn: 0.537 ± 0.029
0.175TrpPro: 0.175 ± 0.015
0.417TrpGln: 0.417 ± 0.021
0.317TrpArg: 0.317 ± 0.02
0.577TrpSer: 0.577 ± 0.03
0.493TrpThr: 0.493 ± 0.03
0.503TrpVal: 0.503 ± 0.029
0.101TrpTrp: 0.101 ± 0.013
0.287TrpTyr: 0.287 ± 0.02
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.064TyrAla: 2.064 ± 0.056
0.226TyrCys: 0.226 ± 0.017
1.882TyrAsp: 1.882 ± 0.054
2.288TyrGlu: 2.288 ± 0.061
2.072TyrPhe: 2.072 ± 0.056
2.279TyrGly: 2.279 ± 0.06
0.824TyrHis: 0.824 ± 0.035
2.121TyrIle: 2.121 ± 0.052
1.816TyrLys: 1.816 ± 0.052
4.143TyrLeu: 4.143 ± 0.081
0.707TyrMet: 0.707 ± 0.034
1.458TyrAsn: 1.458 ± 0.048
1.41TyrPro: 1.41 ± 0.048
2.455TyrGln: 2.455 ± 0.068
1.537TyrArg: 1.537 ± 0.046
2.157TyrSer: 2.157 ± 0.059
1.866TyrThr: 1.866 ± 0.053
2.059TyrVal: 2.059 ± 0.054
0.373TyrTrp: 0.373 ± 0.025
1.508TyrTyr: 1.508 ± 0.05
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.001XaaGln: 0.001 ± 0.001
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.001XaaVal: 0.001 ± 0.001
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.046XaaXaa: 0.046 ± 0.047
Statistics based on 2398 proteins (753840 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski