Amino acid dipepetide frequency for Vesicular exanthema of swine virus serotype A48 (isolate Swine/United States/A48/1948) (VESV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.061AlaAla: 7.061 ± 2.672
1.858AlaCys: 1.858 ± 0.931
3.716AlaAsp: 3.716 ± 1.901
3.716AlaGlu: 3.716 ± 0.587
4.088AlaPhe: 4.088 ± 1.245
3.716AlaGly: 3.716 ± 1.646
2.973AlaHis: 2.973 ± 0.492
2.973AlaIle: 2.973 ± 1.489
3.344AlaLys: 3.344 ± 0.898
8.175AlaLeu: 8.175 ± 1.566
1.115AlaMet: 1.115 ± 1.257
3.716AlaAsn: 3.716 ± 3.677
1.858AlaPro: 1.858 ± 0.464
1.115AlaGln: 1.115 ± 0.558
3.344AlaArg: 3.344 ± 0.624
4.831AlaSer: 4.831 ± 0.865
6.689AlaThr: 6.689 ± 2.646
6.689AlaVal: 6.689 ± 2.239
0.743AlaTrp: 0.743 ± 0.372
1.486AlaTyr: 1.486 ± 0.745
0.0AlaXaa: 0.0 ± 0.0
Cys
2.23CysAla: 2.23 ± 0.558
1.486CysCys: 1.486 ± 0.588
1.115CysAsp: 1.115 ± 0.197
1.115CysGlu: 1.115 ± 0.197
1.115CysPhe: 1.115 ± 0.197
2.601CysGly: 2.601 ± 0.405
0.0CysHis: 0.0 ± 0.0
0.372CysIle: 0.372 ± 0.186
0.372CysLys: 0.372 ± 0.186
0.743CysLeu: 0.743 ± 0.372
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.486CysPro: 1.486 ± 0.745
0.372CysGln: 0.372 ± 0.186
0.0CysArg: 0.0 ± 0.0
0.743CysSer: 0.743 ± 0.294
1.486CysThr: 1.486 ± 0.745
0.372CysVal: 0.372 ± 0.186
0.0CysTrp: 0.0 ± 0.0
1.115CysTyr: 1.115 ± 0.197
0.0CysXaa: 0.0 ± 0.0
Asp
1.858AspAla: 1.858 ± 1.133
1.115AspCys: 1.115 ± 0.738
4.459AspAsp: 4.459 ± 1.215
4.088AspGlu: 4.088 ± 0.855
3.716AspPhe: 3.716 ± 2.266
5.203AspGly: 5.203 ± 1.034
2.23AspHis: 2.23 ± 0.558
1.486AspIle: 1.486 ± 0.588
4.459AspLys: 4.459 ± 0.737
7.432AspLeu: 7.432 ± 3.991
1.115AspMet: 1.115 ± 0.857
2.601AspAsn: 2.601 ± 0.405
2.601AspPro: 2.601 ± 0.752
1.486AspGln: 1.486 ± 0.246
1.115AspArg: 1.115 ± 0.558
4.459AspSer: 4.459 ± 0.737
4.831AspThr: 4.831 ± 2.103
4.088AspVal: 4.088 ± 0.64
1.115AspTrp: 1.115 ± 0.558
1.858AspTyr: 1.858 ± 0.389
0.0AspXaa: 0.0 ± 0.0
Glu
3.716GluAla: 3.716 ± 1.154
0.372GluCys: 0.372 ± 0.186
1.486GluAsp: 1.486 ± 0.745
3.716GluGlu: 3.716 ± 0.778
2.973GluPhe: 2.973 ± 0.916
2.973GluGly: 2.973 ± 1.051
0.743GluHis: 0.743 ± 0.294
2.973GluIle: 2.973 ± 0.65
1.858GluLys: 1.858 ± 0.464
3.344GluLeu: 3.344 ± 0.624
0.743GluMet: 0.743 ± 0.372
3.716GluAsn: 3.716 ± 1.283
3.716GluPro: 3.716 ± 0.587
1.115GluGln: 1.115 ± 0.738
1.858GluArg: 1.858 ± 2.553
3.716GluSer: 3.716 ± 0.929
2.23GluThr: 2.23 ± 0.394
2.973GluVal: 2.973 ± 0.492
0.372GluTrp: 0.372 ± 0.451
1.858GluTyr: 1.858 ± 0.389
0.0GluXaa: 0.0 ± 0.0
Phe
1.486PheAla: 1.486 ± 0.246
0.0PheCys: 0.0 ± 0.0
4.831PheAsp: 4.831 ± 3.119
1.115PheGlu: 1.115 ± 1.257
0.372PhePhe: 0.372 ± 0.451
1.486PheGly: 1.486 ± 1.217
1.115PheHis: 1.115 ± 0.738
1.486PheIle: 1.486 ± 0.745
2.601PheLys: 2.601 ± 0.736
2.973PheLeu: 2.973 ± 1.253
0.743PheMet: 0.743 ± 0.294
2.601PheAsn: 2.601 ± 1.046
0.743PhePro: 0.743 ± 0.294
0.743PheGln: 0.743 ± 0.294
2.23PheArg: 2.23 ± 0.558
3.344PheSer: 3.344 ± 1.043
4.459PheThr: 4.459 ± 1.764
1.486PheVal: 1.486 ± 0.745
0.372PheTrp: 0.372 ± 0.186
3.716PheTyr: 3.716 ± 1.154
0.0PheXaa: 0.0 ± 0.0
Gly
4.459GlyAla: 4.459 ± 1.652
1.115GlyCys: 1.115 ± 0.558
2.973GlyAsp: 2.973 ± 1.051
2.23GlyGlu: 2.23 ± 0.558
1.858GlyPhe: 1.858 ± 1.029
4.459GlyGly: 4.459 ± 0.737
0.372GlyHis: 0.372 ± 0.186
3.716GlyIle: 3.716 ± 0.929
5.574GlyLys: 5.574 ± 0.585
7.061GlyLeu: 7.061 ± 3.573
1.486GlyMet: 1.486 ± 0.745
4.459GlyAsn: 4.459 ± 1.215
4.088GlyPro: 4.088 ± 0.944
1.486GlyGln: 1.486 ± 0.745
1.486GlyArg: 1.486 ± 1.238
4.088GlySer: 4.088 ± 1.908
5.203GlyThr: 5.203 ± 2.643
6.317GlyVal: 6.317 ± 1.501
1.115GlyTrp: 1.115 ± 0.738
1.858GlyTyr: 1.858 ± 0.464
0.0GlyXaa: 0.0 ± 0.0
His
1.486HisAla: 1.486 ± 0.246
0.743HisCys: 0.743 ± 0.294
2.973HisAsp: 2.973 ± 0.65
1.486HisGlu: 1.486 ± 0.745
1.115HisPhe: 1.115 ± 0.738
1.486HisGly: 1.486 ± 0.246
0.743HisHis: 0.743 ± 0.294
1.858HisIle: 1.858 ± 0.389
2.601HisLys: 2.601 ± 1.046
2.23HisLeu: 2.23 ± 1.117
0.372HisMet: 0.372 ± 0.186
0.372HisAsn: 0.372 ± 0.186
0.372HisPro: 0.372 ± 0.186
1.486HisGln: 1.486 ± 0.745
0.743HisArg: 0.743 ± 0.294
0.743HisSer: 0.743 ± 1.444
1.858HisThr: 1.858 ± 0.464
3.716HisVal: 3.716 ± 0.778
0.743HisTrp: 0.743 ± 0.902
0.372HisTyr: 0.372 ± 0.451
0.0HisXaa: 0.0 ± 0.0
Ile
2.973IleAla: 2.973 ± 0.492
0.372IleCys: 0.372 ± 0.451
4.088IleAsp: 4.088 ± 0.944
2.23IleGlu: 2.23 ± 0.394
1.858IlePhe: 1.858 ± 0.464
2.601IleGly: 2.601 ± 0.752
0.743IleHis: 0.743 ± 0.372
2.601IleIle: 2.601 ± 1.303
3.344IleLys: 3.344 ± 0.591
5.203IleLeu: 5.203 ± 1.01
2.23IleMet: 2.23 ± 0.558
4.459IleAsn: 4.459 ± 1.027
4.088IlePro: 4.088 ± 1.908
1.115IleGln: 1.115 ± 1.257
2.23IleArg: 2.23 ± 0.558
4.831IleSer: 4.831 ± 0.864
3.716IleThr: 3.716 ± 1.47
4.459IleVal: 4.459 ± 0.737
0.743IleTrp: 0.743 ± 0.372
1.858IleTyr: 1.858 ± 2.586
0.0IleXaa: 0.0 ± 0.0
Lys
5.574LysAla: 5.574 ± 1.167
0.372LysCys: 0.372 ± 0.186
5.203LysAsp: 5.203 ± 1.01
2.601LysGlu: 2.601 ± 0.736
0.743LysPhe: 0.743 ± 1.302
5.203LysGly: 5.203 ± 0.809
1.115LysHis: 1.115 ± 0.197
2.601LysIle: 2.601 ± 0.736
1.486LysLys: 1.486 ± 1.217
5.203LysLeu: 5.203 ± 2.83
2.601LysMet: 2.601 ± 0.863
3.716LysAsn: 3.716 ± 1.283
4.831LysPro: 4.831 ± 0.864
0.743LysGln: 0.743 ± 0.372
4.459LysArg: 4.459 ± 1.652
2.973LysSer: 2.973 ± 0.492
4.088LysThr: 4.088 ± 0.831
5.946LysVal: 5.946 ± 0.969
1.858LysTrp: 1.858 ± 0.931
0.372LysTyr: 0.372 ± 0.186
0.0LysXaa: 0.0 ± 0.0
Leu
7.804LeuAla: 7.804 ± 3.491
1.115LeuCys: 1.115 ± 0.558
5.203LeuAsp: 5.203 ± 3.449
4.831LeuGlu: 4.831 ± 1.837
2.23LeuPhe: 2.23 ± 0.882
4.459LeuGly: 4.459 ± 0.788
1.858LeuHis: 1.858 ± 1.133
5.203LeuIle: 5.203 ± 1.01
5.946LeuLys: 5.946 ± 2.393
4.831LeuLeu: 4.831 ± 1.113
1.858LeuMet: 1.858 ± 0.389
3.716LeuAsn: 3.716 ± 0.857
4.831LeuPro: 4.831 ± 1.629
2.23LeuGln: 2.23 ± 1.074
7.061LeuArg: 7.061 ± 4.627
5.574LeuSer: 5.574 ± 0.881
7.804LeuThr: 7.804 ± 1.72
3.716LeuVal: 3.716 ± 2.059
0.0LeuTrp: 0.0 ± 0.0
2.973LeuTyr: 2.973 ± 0.65
0.0LeuXaa: 0.0 ± 0.0
Met
2.23MetAla: 2.23 ± 0.558
0.372MetCys: 0.372 ± 0.186
1.486MetAsp: 1.486 ± 0.246
0.372MetGlu: 0.372 ± 0.186
1.115MetPhe: 1.115 ± 0.558
0.743MetGly: 0.743 ± 0.294
0.372MetHis: 0.372 ± 0.186
1.115MetIle: 1.115 ± 0.197
1.115MetLys: 1.115 ± 0.558
1.115MetLeu: 1.115 ± 0.197
0.372MetMet: 0.372 ± 0.186
0.743MetAsn: 0.743 ± 1.444
0.743MetPro: 0.743 ± 0.372
0.372MetGln: 0.372 ± 0.186
0.743MetArg: 0.743 ± 1.302
1.115MetSer: 1.115 ± 0.558
1.858MetThr: 1.858 ± 0.464
3.344MetVal: 3.344 ± 1.099
0.372MetTrp: 0.372 ± 0.186
0.743MetTyr: 0.743 ± 0.294
0.0MetXaa: 0.0 ± 0.0
Asn
2.973AsnAla: 2.973 ± 1.051
1.115AsnCys: 1.115 ± 0.197
2.23AsnAsp: 2.23 ± 1.284
1.486AsnGlu: 1.486 ± 0.745
2.601AsnPhe: 2.601 ± 1.077
3.344AsnGly: 3.344 ± 1.099
2.601AsnHis: 2.601 ± 0.405
1.858AsnIle: 1.858 ± 0.931
3.716AsnLys: 3.716 ± 0.587
5.203AsnLeu: 5.203 ± 1.066
0.743AsnMet: 0.743 ± 0.51
3.716AsnAsn: 3.716 ± 0.956
5.574AsnPro: 5.574 ± 0.585
1.486AsnGln: 1.486 ± 0.246
1.858AsnArg: 1.858 ± 0.464
3.344AsnSer: 3.344 ± 2.086
3.716AsnThr: 3.716 ± 1.283
0.743AsnVal: 0.743 ± 0.372
1.115AsnTrp: 1.115 ± 0.197
1.858AsnTyr: 1.858 ± 2.763
0.0AsnXaa: 0.0 ± 0.0
Pro
5.574ProAla: 5.574 ± 0.881
0.372ProCys: 0.372 ± 0.451
4.459ProAsp: 4.459 ± 2.953
1.858ProGlu: 1.858 ± 1.029
1.486ProPhe: 1.486 ± 0.588
3.344ProGly: 3.344 ± 1.615
1.858ProHis: 1.858 ± 0.389
4.831ProIle: 4.831 ± 1.113
4.088ProLys: 4.088 ± 2.048
4.088ProLeu: 4.088 ± 0.944
0.372ProMet: 0.372 ± 0.186
0.743ProAsn: 0.743 ± 0.372
4.459ProPro: 4.459 ± 1.215
1.858ProGln: 1.858 ± 0.389
2.973ProArg: 2.973 ± 0.492
4.088ProSer: 4.088 ± 0.841
4.459ProThr: 4.459 ± 1.652
2.973ProVal: 2.973 ± 0.916
0.743ProTrp: 0.743 ± 0.372
4.088ProTyr: 4.088 ± 0.831
0.0ProXaa: 0.0 ± 0.0
Gln
2.601GlnAla: 2.601 ± 1.046
0.0GlnCys: 0.0 ± 0.0
0.372GlnAsp: 0.372 ± 1.372
0.372GlnGlu: 0.372 ± 0.451
1.486GlnPhe: 1.486 ± 0.745
2.23GlnGly: 2.23 ± 0.882
1.486GlnHis: 1.486 ± 0.246
2.23GlnIle: 2.23 ± 1.074
1.858GlnLys: 1.858 ± 0.464
2.601GlnLeu: 2.601 ± 1.046
0.0GlnMet: 0.0 ± 0.0
0.372GlnAsn: 0.372 ± 0.186
4.088GlnPro: 4.088 ± 0.64
2.601GlnGln: 2.601 ± 0.405
1.858GlnArg: 1.858 ± 0.389
1.858GlnSer: 1.858 ± 0.464
1.115GlnThr: 1.115 ± 0.197
0.743GlnVal: 0.743 ± 0.372
0.743GlnTrp: 0.743 ± 0.294
0.372GlnTyr: 0.372 ± 0.451
0.0GlnXaa: 0.0 ± 0.0
Arg
4.088ArgAla: 4.088 ± 2.284
1.486ArgCys: 1.486 ± 0.246
1.486ArgAsp: 1.486 ± 1.238
1.486ArgGlu: 1.486 ± 0.745
1.858ArgPhe: 1.858 ± 0.389
2.973ArgGly: 2.973 ± 1.429
2.23ArgHis: 2.23 ± 1.074
2.973ArgIle: 2.973 ± 3.895
2.973ArgLys: 2.973 ± 0.492
4.088ArgLeu: 4.088 ± 1.467
0.743ArgMet: 0.743 ± 0.372
2.23ArgAsn: 2.23 ± 0.394
2.23ArgPro: 2.23 ± 0.558
2.23ArgGln: 2.23 ± 1.074
3.716ArgArg: 3.716 ± 1.861
2.973ArgSer: 2.973 ± 1.051
3.344ArgThr: 3.344 ± 1.675
3.344ArgVal: 3.344 ± 0.591
0.372ArgTrp: 0.372 ± 0.451
1.115ArgTyr: 1.115 ± 0.558
0.0ArgXaa: 0.0 ± 0.0
Ser
2.973SerAla: 2.973 ± 0.492
1.858SerCys: 1.858 ± 0.931
2.601SerAsp: 2.601 ± 0.752
3.344SerGlu: 3.344 ± 0.624
1.486SerPhe: 1.486 ± 1.217
6.317SerGly: 6.317 ± 0.989
2.23SerHis: 2.23 ± 1.117
4.459SerIle: 4.459 ± 1.764
6.317SerLys: 6.317 ± 1.501
6.689SerLeu: 6.689 ± 1.247
1.858SerMet: 1.858 ± 1.029
4.088SerAsn: 4.088 ± 1.196
2.23SerPro: 2.23 ± 0.558
4.088SerGln: 4.088 ± 2.505
3.716SerArg: 3.716 ± 2.495
4.459SerSer: 4.459 ± 1.215
6.689SerThr: 6.689 ± 3.826
2.973SerVal: 2.973 ± 1.253
0.372SerTrp: 0.372 ± 0.186
2.23SerTyr: 2.23 ± 1.582
0.0SerXaa: 0.0 ± 0.0
Thr
4.831ThrAla: 4.831 ± 1.113
1.115ThrCys: 1.115 ± 0.197
5.574ThrAsp: 5.574 ± 0.585
5.574ThrGlu: 5.574 ± 0.585
4.088ThrPhe: 4.088 ± 1.336
5.574ThrGly: 5.574 ± 1.167
2.23ThrHis: 2.23 ± 0.882
4.831ThrIle: 4.831 ± 1.629
2.601ThrLys: 2.601 ± 0.752
6.689ThrLeu: 6.689 ± 2.086
1.115ThrMet: 1.115 ± 0.738
3.344ThrAsn: 3.344 ± 0.898
2.973ThrPro: 2.973 ± 0.492
1.486ThrGln: 1.486 ± 0.246
2.23ThrArg: 2.23 ± 0.394
6.317ThrSer: 6.317 ± 1.501
5.203ThrThr: 5.203 ± 2.058
5.203ThrVal: 5.203 ± 0.809
2.23ThrTrp: 2.23 ± 0.394
1.486ThrTyr: 1.486 ± 0.246
0.0ThrXaa: 0.0 ± 0.0
Val
4.088ValAla: 4.088 ± 1.245
1.115ValCys: 1.115 ± 0.558
5.203ValAsp: 5.203 ± 2.022
3.344ValGlu: 3.344 ± 1.546
2.23ValPhe: 2.23 ± 0.882
2.973ValGly: 2.973 ± 0.916
1.486ValHis: 1.486 ± 0.246
4.831ValIle: 4.831 ± 0.776
5.203ValLys: 5.203 ± 0.809
4.088ValLeu: 4.088 ± 0.944
1.115ValMet: 1.115 ± 0.558
3.344ValAsn: 3.344 ± 0.591
5.574ValPro: 5.574 ± 1.652
1.486ValGln: 1.486 ± 1.188
4.831ValArg: 4.831 ± 1.293
4.088ValSer: 4.088 ± 0.64
4.088ValThr: 4.088 ± 0.944
6.317ValVal: 6.317 ± 1.501
0.0ValTrp: 0.0 ± 0.0
2.973ValTyr: 2.973 ± 1.176
0.0ValXaa: 0.0 ± 0.0
Trp
0.743TrpAla: 0.743 ± 0.372
0.372TrpCys: 0.372 ± 0.186
0.743TrpAsp: 0.743 ± 0.372
0.0TrpGlu: 0.0 ± 0.0
0.372TrpPhe: 0.372 ± 0.451
0.743TrpGly: 0.743 ± 0.372
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.115TrpLys: 1.115 ± 0.558
0.743TrpLeu: 0.743 ± 0.294
1.115TrpMet: 1.115 ± 0.197
0.743TrpAsn: 0.743 ± 0.372
0.743TrpPro: 0.743 ± 0.902
0.743TrpGln: 0.743 ± 0.372
0.372TrpArg: 0.372 ± 0.186
2.973TrpSer: 2.973 ± 1.176
0.372TrpThr: 0.372 ± 0.186
0.0TrpVal: 0.0 ± 0.0
0.372TrpTrp: 0.372 ± 0.451
1.486TrpTyr: 1.486 ± 0.246
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.459TyrAla: 4.459 ± 2.191
0.372TyrCys: 0.372 ± 0.186
1.115TyrAsp: 1.115 ± 0.558
1.486TyrGlu: 1.486 ± 0.588
1.115TyrPhe: 1.115 ± 0.738
2.973TyrGly: 2.973 ± 1.051
1.115TyrHis: 1.115 ± 0.738
3.344TyrIle: 3.344 ± 0.591
1.115TyrLys: 1.115 ± 1.322
0.743TyrLeu: 0.743 ± 0.294
0.372TyrMet: 0.372 ± 0.186
2.973TyrAsn: 2.973 ± 0.916
1.486TyrPro: 1.486 ± 0.588
0.743TyrGln: 0.743 ± 1.302
1.115TyrArg: 1.115 ± 0.197
4.459TyrSer: 4.459 ± 2.4
1.486TyrThr: 1.486 ± 0.246
2.973TyrVal: 2.973 ± 0.65
0.372TyrTrp: 0.372 ± 0.186
1.858TyrTyr: 1.858 ± 1.338
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (2692 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski