Amino acid dipepetide frequency for Tauraco erythrolophus (Red-crested turaco)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.561AlaAla: 5.561 ± 0.06
1.318AlaCys: 1.318 ± 0.024
2.978AlaAsp: 2.978 ± 0.027
4.487AlaGlu: 4.487 ± 0.044
2.629AlaPhe: 2.629 ± 0.032
3.813AlaGly: 3.813 ± 0.041
1.316AlaHis: 1.316 ± 0.02
3.059AlaIle: 3.059 ± 0.033
3.732AlaLys: 3.732 ± 0.03
6.453AlaLeu: 6.453 ± 0.048
1.489AlaMet: 1.489 ± 0.018
2.265AlaAsn: 2.265 ± 0.024
2.942AlaPro: 2.942 ± 0.032
2.716AlaGln: 2.716 ± 0.033
3.053AlaArg: 3.053 ± 0.03
5.131AlaSer: 5.131 ± 0.044
3.316AlaThr: 3.316 ± 0.036
4.841AlaVal: 4.841 ± 0.038
0.725AlaTrp: 0.725 ± 0.014
1.665AlaTyr: 1.665 ± 0.024
0.002AlaXaa: 0.002 ± 0.001
Cys
1.198CysAla: 1.198 ± 0.023
0.662CysCys: 0.662 ± 0.015
1.077CysAsp: 1.077 ± 0.026
1.331CysGlu: 1.331 ± 0.025
0.916CysPhe: 0.916 ± 0.017
1.424CysGly: 1.424 ± 0.028
0.628CysHis: 0.628 ± 0.015
1.188CysIle: 1.188 ± 0.024
1.369CysLys: 1.369 ± 0.022
2.155CysLeu: 2.155 ± 0.027
0.442CysMet: 0.442 ± 0.011
0.924CysAsn: 0.924 ± 0.019
1.183CysPro: 1.183 ± 0.023
1.075CysGln: 1.075 ± 0.021
1.191CysArg: 1.191 ± 0.019
1.985CysSer: 1.985 ± 0.029
1.18CysThr: 1.18 ± 0.021
1.403CysVal: 1.403 ± 0.027
0.29CysTrp: 0.29 ± 0.008
0.691CysTyr: 0.691 ± 0.015
0.0CysXaa: 0.0 ± 0.0
Asp
2.948AspAla: 2.948 ± 0.029
1.096AspCys: 1.096 ± 0.022
2.881AspAsp: 2.881 ± 0.04
3.856AspGlu: 3.856 ± 0.039
2.286AspPhe: 2.286 ± 0.024
3.209AspGly: 3.209 ± 0.036
1.197AspHis: 1.197 ± 0.018
3.041AspIle: 3.041 ± 0.028
2.849AspLys: 2.849 ± 0.031
5.155AspLeu: 5.155 ± 0.039
1.205AspMet: 1.205 ± 0.017
1.94AspAsn: 1.94 ± 0.025
2.605AspPro: 2.605 ± 0.026
1.899AspGln: 1.899 ± 0.023
2.453AspArg: 2.453 ± 0.03
4.062AspSer: 4.062 ± 0.04
2.5AspThr: 2.5 ± 0.028
3.231AspVal: 3.231 ± 0.032
0.704AspTrp: 0.704 ± 0.016
1.651AspTyr: 1.651 ± 0.023
0.001AspXaa: 0.001 ± 0.0
Glu
4.682GluAla: 4.682 ± 0.045
1.32GluCys: 1.32 ± 0.03
4.569GluAsp: 4.569 ± 0.04
7.802GluGlu: 7.802 ± 0.082
2.222GluPhe: 2.222 ± 0.025
3.935GluGly: 3.935 ± 0.039
1.59GluHis: 1.59 ± 0.022
3.535GluIle: 3.535 ± 0.033
5.881GluLys: 5.881 ± 0.06
6.337GluLeu: 6.337 ± 0.053
1.752GluMet: 1.752 ± 0.022
3.558GluAsn: 3.558 ± 0.033
2.519GluPro: 2.519 ± 0.029
3.18GluGln: 3.18 ± 0.037
3.936GluArg: 3.936 ± 0.047
4.49GluSer: 4.49 ± 0.039
3.566GluThr: 3.566 ± 0.034
4.554GluVal: 4.554 ± 0.036
0.767GluTrp: 0.767 ± 0.015
1.868GluTyr: 1.868 ± 0.023
0.002GluXaa: 0.002 ± 0.001
Phe
2.183PheAla: 2.183 ± 0.027
1.009PheCys: 1.009 ± 0.02
1.821PheAsp: 1.821 ± 0.023
2.162PheGlu: 2.162 ± 0.021
1.984PhePhe: 1.984 ± 0.028
2.3PheGly: 2.3 ± 0.032
1.079PheHis: 1.079 ± 0.017
2.089PheIle: 2.089 ± 0.025
2.32PheLys: 2.32 ± 0.024
4.192PheLeu: 4.192 ± 0.036
0.79PheMet: 0.79 ± 0.014
1.557PheAsn: 1.557 ± 0.021
1.961PhePro: 1.961 ± 0.027
1.866PheGln: 1.866 ± 0.021
2.046PheArg: 2.046 ± 0.022
3.485PheSer: 3.485 ± 0.032
2.349PheThr: 2.349 ± 0.027
2.382PheVal: 2.382 ± 0.026
0.547PheTrp: 0.547 ± 0.011
1.356PheTyr: 1.356 ± 0.019
0.0PheXaa: 0.0 ± 0.0
Gly
3.399GlyAla: 3.399 ± 0.039
1.259GlyCys: 1.259 ± 0.022
2.926GlyAsp: 2.926 ± 0.032
3.738GlyGlu: 3.738 ± 0.042
2.546GlyPhe: 2.546 ± 0.029
3.754GlyGly: 3.754 ± 0.05
1.49GlyHis: 1.49 ± 0.024
3.066GlyIle: 3.066 ± 0.03
3.984GlyLys: 3.984 ± 0.036
5.171GlyLeu: 5.171 ± 0.053
1.354GlyMet: 1.354 ± 0.022
2.794GlyAsn: 2.794 ± 0.031
2.699GlyPro: 2.699 ± 0.066
2.441GlyGln: 2.441 ± 0.031
3.241GlyArg: 3.241 ± 0.035
4.918GlySer: 4.918 ± 0.041
3.338GlyThr: 3.338 ± 0.035
3.418GlyVal: 3.418 ± 0.033
0.774GlyTrp: 0.774 ± 0.015
1.852GlyTyr: 1.852 ± 0.025
0.001GlyXaa: 0.001 ± 0.001
His
1.321HisAla: 1.321 ± 0.02
0.695HisCys: 0.695 ± 0.014
0.911HisAsp: 0.911 ± 0.014
1.339HisGlu: 1.339 ± 0.017
1.062HisPhe: 1.062 ± 0.017
1.459HisGly: 1.459 ± 0.02
0.861HisHis: 0.861 ± 0.017
1.332HisIle: 1.332 ± 0.018
1.46HisLys: 1.46 ± 0.021
2.865HisLeu: 2.865 ± 0.03
0.569HisMet: 0.569 ± 0.014
0.958HisAsn: 0.958 ± 0.016
1.451HisPro: 1.451 ± 0.022
1.168HisGln: 1.168 ± 0.019
1.401HisArg: 1.401 ± 0.019
2.157HisSer: 2.157 ± 0.026
1.276HisThr: 1.276 ± 0.024
1.535HisVal: 1.535 ± 0.021
0.443HisTrp: 0.443 ± 0.011
0.861HisTyr: 0.861 ± 0.014
0.0HisXaa: 0.0 ± 0.0
Ile
3.082IleAla: 3.082 ± 0.03
1.212IleCys: 1.212 ± 0.021
2.336IleAsp: 2.336 ± 0.028
2.986IleGlu: 2.986 ± 0.031
2.234IlePhe: 2.234 ± 0.029
2.474IleGly: 2.474 ± 0.028
1.359IleHis: 1.359 ± 0.019
2.787IleIle: 2.787 ± 0.034
3.099IleLys: 3.099 ± 0.033
5.007IleLeu: 5.007 ± 0.046
1.095IleMet: 1.095 ± 0.018
2.174IleAsn: 2.174 ± 0.029
2.845IlePro: 2.845 ± 0.026
2.462IleGln: 2.462 ± 0.027
2.633IleArg: 2.633 ± 0.026
4.092IleSer: 4.092 ± 0.035
2.858IleThr: 2.858 ± 0.026
2.982IleVal: 2.982 ± 0.032
0.581IleTrp: 0.581 ± 0.011
1.587IleTyr: 1.587 ± 0.024
0.0IleXaa: 0.0 ± 0.0
Lys
4.269LysAla: 4.269 ± 0.037
1.264LysCys: 1.264 ± 0.022
3.624LysAsp: 3.624 ± 0.032
5.908LysGlu: 5.908 ± 0.061
2.091LysPhe: 2.091 ± 0.024
3.45LysGly: 3.45 ± 0.047
1.586LysHis: 1.586 ± 0.02
3.249LysIle: 3.249 ± 0.03
5.613LysLys: 5.613 ± 0.056
5.849LysLeu: 5.849 ± 0.043
1.577LysMet: 1.577 ± 0.02
2.856LysAsn: 2.856 ± 0.032
3.074LysPro: 3.074 ± 0.036
2.967LysGln: 2.967 ± 0.037
3.653LysArg: 3.653 ± 0.036
4.376LysSer: 4.376 ± 0.045
3.487LysThr: 3.487 ± 0.031
3.778LysVal: 3.778 ± 0.033
0.682LysTrp: 0.682 ± 0.012
1.916LysTyr: 1.916 ± 0.023
0.0LysXaa: 0.0 ± 0.0
Leu
6.196LeuAla: 6.196 ± 0.054
2.193LeuCys: 2.193 ± 0.03
5.053LeuAsp: 5.053 ± 0.045
7.203LeuGlu: 7.203 ± 0.062
3.677LeuPhe: 3.677 ± 0.043
5.321LeuGly: 5.321 ± 0.046
2.677LeuHis: 2.677 ± 0.028
4.312LeuIle: 4.312 ± 0.042
6.608LeuLys: 6.608 ± 0.053
9.981LeuLeu: 9.981 ± 0.069
2.064LeuMet: 2.064 ± 0.022
3.942LeuAsn: 3.942 ± 0.037
5.395LeuPro: 5.395 ± 0.049
5.49LeuGln: 5.49 ± 0.05
5.245LeuArg: 5.245 ± 0.044
7.798LeuSer: 7.798 ± 0.053
4.946LeuThr: 4.946 ± 0.037
5.477LeuVal: 5.477 ± 0.043
1.084LeuTrp: 1.084 ± 0.017
2.842LeuTyr: 2.842 ± 0.031
0.001LeuXaa: 0.001 ± 0.001
Met
1.6MetAla: 1.6 ± 0.021
0.435MetCys: 0.435 ± 0.012
1.311MetAsp: 1.311 ± 0.021
1.895MetGlu: 1.895 ± 0.024
0.863MetPhe: 0.863 ± 0.016
1.262MetGly: 1.262 ± 0.022
0.505MetHis: 0.505 ± 0.011
1.021MetIle: 1.021 ± 0.017
1.611MetLys: 1.611 ± 0.02
2.048MetLeu: 2.048 ± 0.023
0.599MetMet: 0.599 ± 0.014
1.02MetAsn: 1.02 ± 0.019
1.023MetPro: 1.023 ± 0.018
1.011MetGln: 1.011 ± 0.018
1.064MetArg: 1.064 ± 0.014
1.593MetSer: 1.593 ± 0.023
1.147MetThr: 1.147 ± 0.019
1.44MetVal: 1.44 ± 0.021
0.26MetTrp: 0.26 ± 0.009
0.679MetTyr: 0.679 ± 0.014
0.0MetXaa: 0.0 ± 0.0
Asn
2.305AsnAla: 2.305 ± 0.028
0.961AsnCys: 0.961 ± 0.018
1.752AsnAsp: 1.752 ± 0.02
2.609AsnGlu: 2.609 ± 0.027
1.651AsnPhe: 1.651 ± 0.02
2.845AsnGly: 2.845 ± 0.036
1.001AsnHis: 1.001 ± 0.017
2.554AsnIle: 2.554 ± 0.023
2.692AsnLys: 2.692 ± 0.027
4.252AsnLeu: 4.252 ± 0.033
1.043AsnMet: 1.043 ± 0.016
1.862AsnAsn: 1.862 ± 0.029
2.292AsnPro: 2.292 ± 0.028
1.741AsnGln: 1.741 ± 0.022
2.136AsnArg: 2.136 ± 0.024
3.466AsnSer: 3.466 ± 0.04
2.265AsnThr: 2.265 ± 0.024
2.496AsnVal: 2.496 ± 0.028
0.512AsnTrp: 0.512 ± 0.011
1.332AsnTyr: 1.332 ± 0.019
0.001AsnXaa: 0.001 ± 0.0
Pro
3.594ProAla: 3.594 ± 0.039
1.029ProCys: 1.029 ± 0.021
2.61ProAsp: 2.61 ± 0.029
3.847ProGlu: 3.847 ± 0.032
1.893ProPhe: 1.893 ± 0.023
3.562ProGly: 3.562 ± 0.101
1.219ProHis: 1.219 ± 0.018
1.954ProIle: 1.954 ± 0.022
2.757ProLys: 2.757 ± 0.032
4.644ProLeu: 4.644 ± 0.041
0.93ProMet: 0.93 ± 0.015
1.906ProAsn: 1.906 ± 0.024
4.12ProPro: 4.12 ± 0.078
2.28ProGln: 2.28 ± 0.036
2.569ProArg: 2.569 ± 0.029
4.931ProSer: 4.931 ± 0.055
2.651ProThr: 2.651 ± 0.031
3.678ProVal: 3.678 ± 0.039
0.539ProTrp: 0.539 ± 0.011
1.433ProTyr: 1.433 ± 0.019
0.001ProXaa: 0.001 ± 0.001
Gln
2.943GlnAla: 2.943 ± 0.034
0.997GlnCys: 0.997 ± 0.018
2.205GlnAsp: 2.205 ± 0.02
3.666GlnGlu: 3.666 ± 0.039
1.464GlnPhe: 1.464 ± 0.024
2.405GlnGly: 2.405 ± 0.032
1.275GlnHis: 1.275 ± 0.021
2.261GlnIle: 2.261 ± 0.025
3.246GlnLys: 3.246 ± 0.034
4.565GlnLeu: 4.565 ± 0.04
1.09GlnMet: 1.09 ± 0.017
2.044GlnAsn: 2.044 ± 0.025
2.258GlnPro: 2.258 ± 0.037
2.885GlnGln: 2.885 ± 0.054
2.642GlnArg: 2.642 ± 0.029
3.174GlnSer: 3.174 ± 0.037
2.324GlnThr: 2.324 ± 0.029
2.76GlnVal: 2.76 ± 0.03
0.532GlnTrp: 0.532 ± 0.013
1.327GlnTyr: 1.327 ± 0.022
0.002GlnXaa: 0.002 ± 0.001
Arg
3.036ArgAla: 3.036 ± 0.031
1.107ArgCys: 1.107 ± 0.023
2.628ArgAsp: 2.628 ± 0.032
3.856ArgGlu: 3.856 ± 0.039
1.979ArgPhe: 1.979 ± 0.023
2.972ArgGly: 2.972 ± 0.039
1.485ArgHis: 1.485 ± 0.021
2.595ArgIle: 2.595 ± 0.03
4.069ArgLys: 4.069 ± 0.041
5.209ArgLeu: 5.209 ± 0.052
1.149ArgMet: 1.149 ± 0.019
2.252ArgAsn: 2.252 ± 0.025
2.441ArgPro: 2.441 ± 0.024
2.456ArgGln: 2.456 ± 0.027
3.723ArgArg: 3.723 ± 0.044
3.995ArgSer: 3.995 ± 0.049
2.699ArgThr: 2.699 ± 0.03
3.077ArgVal: 3.077 ± 0.028
0.65ArgTrp: 0.65 ± 0.014
1.604ArgTyr: 1.604 ± 0.021
0.001ArgXaa: 0.001 ± 0.0
Ser
5.095SerAla: 5.095 ± 0.042
1.813SerCys: 1.813 ± 0.028
4.043SerAsp: 4.043 ± 0.042
5.061SerGlu: 5.061 ± 0.049
3.108SerPhe: 3.108 ± 0.028
4.926SerGly: 4.926 ± 0.047
1.987SerHis: 1.987 ± 0.024
3.58SerIle: 3.58 ± 0.03
4.502SerLys: 4.502 ± 0.044
8.041SerLeu: 8.041 ± 0.05
1.649SerMet: 1.649 ± 0.021
3.139SerAsn: 3.139 ± 0.033
5.066SerPro: 5.066 ± 0.07
3.568SerGln: 3.568 ± 0.039
4.134SerArg: 4.134 ± 0.047
9.18SerSer: 9.18 ± 0.107
4.538SerThr: 4.538 ± 0.038
5.149SerVal: 5.149 ± 0.042
0.996SerTrp: 0.996 ± 0.018
2.272SerTyr: 2.272 ± 0.026
0.001SerXaa: 0.001 ± 0.0
Thr
3.743ThrAla: 3.743 ± 0.039
1.322ThrCys: 1.322 ± 0.03
2.7ThrAsp: 2.7 ± 0.027
3.728ThrGlu: 3.728 ± 0.032
2.192ThrPhe: 2.192 ± 0.024
3.345ThrGly: 3.345 ± 0.041
1.173ThrHis: 1.173 ± 0.018
2.606ThrIle: 2.606 ± 0.029
2.967ThrLys: 2.967 ± 0.027
5.131ThrLeu: 5.131 ± 0.041
1.156ThrMet: 1.156 ± 0.018
1.953ThrAsn: 1.953 ± 0.022
3.056ThrPro: 3.056 ± 0.043
2.16ThrGln: 2.16 ± 0.025
2.361ThrArg: 2.361 ± 0.025
4.696ThrSer: 4.696 ± 0.047
2.97ThrThr: 2.97 ± 0.036
4.075ThrVal: 4.075 ± 0.036
0.667ThrTrp: 0.667 ± 0.015
1.544ThrTyr: 1.544 ± 0.02
0.001ThrXaa: 0.001 ± 0.0
Val
4.072ValAla: 4.072 ± 0.035
1.557ValCys: 1.557 ± 0.028
3.198ValAsp: 3.198 ± 0.03
3.921ValGlu: 3.921 ± 0.033
2.813ValPhe: 2.813 ± 0.031
3.309ValGly: 3.309 ± 0.034
1.579ValHis: 1.579 ± 0.019
3.325ValIle: 3.325 ± 0.034
3.859ValLys: 3.859 ± 0.031
6.312ValLeu: 6.312 ± 0.045
1.414ValMet: 1.414 ± 0.02
2.585ValAsn: 2.585 ± 0.026
3.439ValPro: 3.439 ± 0.031
2.838ValGln: 2.838 ± 0.029
3.049ValArg: 3.049 ± 0.029
5.0ValSer: 5.0 ± 0.039
3.844ValThr: 3.844 ± 0.035
4.411ValVal: 4.411 ± 0.037
0.734ValTrp: 0.734 ± 0.015
1.872ValTyr: 1.872 ± 0.025
0.001ValXaa: 0.001 ± 0.001
Trp
0.702TrpAla: 0.702 ± 0.017
0.252TrpCys: 0.252 ± 0.009
0.681TrpAsp: 0.681 ± 0.015
0.801TrpGlu: 0.801 ± 0.015
0.465TrpPhe: 0.465 ± 0.01
0.622TrpGly: 0.622 ± 0.018
0.311TrpHis: 0.311 ± 0.009
0.678TrpIle: 0.678 ± 0.015
0.92TrpLys: 0.92 ± 0.016
1.175TrpLeu: 1.175 ± 0.019
0.326TrpMet: 0.326 ± 0.01
0.747TrpAsn: 0.747 ± 0.015
0.424TrpPro: 0.424 ± 0.01
0.555TrpGln: 0.555 ± 0.012
0.647TrpArg: 0.647 ± 0.013
0.917TrpSer: 0.917 ± 0.016
0.653TrpThr: 0.653 ± 0.014
0.659TrpVal: 0.659 ± 0.014
0.191TrpTrp: 0.191 ± 0.007
0.375TrpTyr: 0.375 ± 0.011
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.561TyrAla: 1.561 ± 0.02
0.81TyrCys: 0.81 ± 0.017
1.466TyrAsp: 1.466 ± 0.022
1.87TyrGlu: 1.87 ± 0.022
1.403TyrPhe: 1.403 ± 0.02
1.772TyrGly: 1.772 ± 0.025
0.803TyrHis: 0.803 ± 0.014
1.652TyrIle: 1.652 ± 0.016
1.731TyrLys: 1.731 ± 0.023
2.966TyrLeu: 2.966 ± 0.028
0.694TyrMet: 0.694 ± 0.013
1.287TyrAsn: 1.287 ± 0.02
1.351TyrPro: 1.351 ± 0.019
1.306TyrGln: 1.306 ± 0.02
1.807TyrArg: 1.807 ± 0.025
2.403TyrSer: 2.403 ± 0.026
1.635TyrThr: 1.635 ± 0.025
1.787TyrVal: 1.787 ± 0.025
0.421TyrTrp: 0.421 ± 0.014
1.112TyrTyr: 1.112 ± 0.02
0.001TyrXaa: 0.001 ± 0.0
Xaa
0.001XaaAla: 0.001 ± 0.001
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.001XaaGlu: 0.001 ± 0.001
0.001XaaPhe: 0.001 ± 0.0
0.001XaaGly: 0.001 ± 0.001
0.0XaaHis: 0.0 ± 0.0
0.001XaaIle: 0.001 ± 0.0
0.001XaaLys: 0.001 ± 0.001
0.001XaaLeu: 0.001 ± 0.0
0.001XaaMet: 0.001 ± 0.001
0.001XaaAsn: 0.001 ± 0.0
0.002XaaPro: 0.002 ± 0.001
0.001XaaGln: 0.001 ± 0.0
0.002XaaArg: 0.002 ± 0.001
0.001XaaSer: 0.001 ± 0.0
0.001XaaThr: 0.001 ± 0.001
0.001XaaVal: 0.001 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.101XaaXaa: 0.101 ± 0.01
Statistics based on 10099 proteins (4098719 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski