Human papillomavirus type 131

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Gammapapillomavirus; Gammapapillomavirus 14

Average proteome isoelectric point is 6.16

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|E7BQ92|E7BQ92_9PAPI Major capsid protein L1 OS=Human papillomavirus type 131 OX=909330 GN=L1 PE=3 SV=1
MM1 pKa = 7.4SKK3 pKa = 9.74IRR5 pKa = 11.84RR6 pKa = 11.84KK7 pKa = 9.7RR8 pKa = 11.84ASPSDD13 pKa = 3.79LYY15 pKa = 10.09NTCLQGGDD23 pKa = 4.08CVPDD27 pKa = 3.43VKK29 pKa = 11.27NKK31 pKa = 10.33FEE33 pKa = 4.95NNTIADD39 pKa = 3.96WLLKK43 pKa = 10.07IFGSIVYY50 pKa = 9.49FGNLGIGTGRR60 pKa = 11.84GTGGLFGYY68 pKa = 10.36RR69 pKa = 11.84PFGSANAGKK78 pKa = 9.02PIQEE82 pKa = 4.27LPITRR87 pKa = 11.84PNVVIEE93 pKa = 4.73PIGPTPIIPVEE104 pKa = 4.24PGASSIVPLVEE115 pKa = 3.79GTPDD119 pKa = 2.9ISFISPDD126 pKa = 3.35AGPGVGGEE134 pKa = 4.27DD135 pKa = 3.02IEE137 pKa = 5.45LFTISDD143 pKa = 3.81PTRR146 pKa = 11.84DD147 pKa = 3.12IGGVGGGPTVISTEE161 pKa = 3.97EE162 pKa = 4.16SEE164 pKa = 4.44TTIIDD169 pKa = 4.16AFPSPAGPKK178 pKa = 9.37QVFYY182 pKa = 11.15DD183 pKa = 3.31AATNITLEE191 pKa = 4.2TQINPFINADD201 pKa = 3.35INNTNIFVDD210 pKa = 3.61TTIAGEE216 pKa = 4.43TVGDD220 pKa = 3.81PSFEE224 pKa = 4.66NIPLEE229 pKa = 4.23RR230 pKa = 11.84LDD232 pKa = 3.66LQEE235 pKa = 5.25FEE237 pKa = 4.78IEE239 pKa = 4.19EE240 pKa = 4.79PPTEE244 pKa = 4.33STPVTAFGRR253 pKa = 11.84AFNRR257 pKa = 11.84ARR259 pKa = 11.84DD260 pKa = 3.65LYY262 pKa = 11.26SRR264 pKa = 11.84FIEE267 pKa = 3.83QVPITEE273 pKa = 4.67PEE275 pKa = 4.19FLVQPSRR282 pKa = 11.84LVQFEE287 pKa = 4.47SEE289 pKa = 4.47NPAFDD294 pKa = 4.94PDD296 pKa = 3.25VSLAFEE302 pKa = 4.59HH303 pKa = 7.5DD304 pKa = 3.83VAEE307 pKa = 4.37LQAAPSSEE315 pKa = 3.76FADD318 pKa = 4.22IIRR321 pKa = 11.84LSRR324 pKa = 11.84PRR326 pKa = 11.84LTATVEE332 pKa = 3.91GTVRR336 pKa = 11.84VSRR339 pKa = 11.84LGTRR343 pKa = 11.84AALTTRR349 pKa = 11.84SGLTVGPQVHH359 pKa = 6.99FYY361 pKa = 10.26MDD363 pKa = 4.19LSEE366 pKa = 4.61IAAAEE371 pKa = 4.33NIEE374 pKa = 4.09MLPIAEE380 pKa = 4.49YY381 pKa = 9.68SHH383 pKa = 6.89EE384 pKa = 4.29STVVDD389 pKa = 4.41DD390 pKa = 5.55LLAHH394 pKa = 5.68TVIDD398 pKa = 4.5DD399 pKa = 3.61VANAANINYY408 pKa = 8.71TEE410 pKa = 4.9ADD412 pKa = 3.83LEE414 pKa = 4.47DD415 pKa = 4.35LLSEE419 pKa = 4.27QFNNSHH425 pKa = 6.29IVVTSTTEE433 pKa = 3.57EE434 pKa = 4.81GEE436 pKa = 4.32TLNIPTLPPNAVLKK450 pKa = 10.73VFVPDD455 pKa = 3.31VGDD458 pKa = 3.9GLFVAYY464 pKa = 9.93GVDD467 pKa = 3.31TASNTNIVLPNNLPVEE483 pKa = 4.17PSLIITDD490 pKa = 3.42SHH492 pKa = 8.13DD493 pKa = 4.04FEE495 pKa = 5.07LHH497 pKa = 5.44PALWPRR503 pKa = 11.84KK504 pKa = 8.67RR505 pKa = 11.84RR506 pKa = 11.84RR507 pKa = 11.84LDD509 pKa = 3.23LFF511 pKa = 4.04

Molecular weight: 55.38 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|E7BQ87|E7BQ87_9PAPI Protein E7 OS=Human papillomavirus type 131 OX=909330 GN=E7 PE=3 SV=1
MM1 pKa = 7.95ASTYY5 pKa = 10.57PNNLVDD11 pKa = 5.3LCSACNISFFNLHH24 pKa = 6.86LDD26 pKa = 4.43CLFCKK31 pKa = 10.47HH32 pKa = 6.48KK33 pKa = 10.33LTILDD38 pKa = 3.74LAGFHH43 pKa = 5.84QKK45 pKa = 9.69QLSVVWRR52 pKa = 11.84NDD54 pKa = 2.96KK55 pKa = 11.36AFGSCSKK62 pKa = 10.55CLRR65 pKa = 11.84LTANYY70 pKa = 9.42EE71 pKa = 3.69RR72 pKa = 11.84EE73 pKa = 3.7NYY75 pKa = 8.75YY76 pKa = 10.3RR77 pKa = 11.84CSVKK81 pKa = 10.47GSLISGLLKK90 pKa = 10.21TPLKK94 pKa = 10.6DD95 pKa = 2.89ITVRR99 pKa = 11.84CLYY102 pKa = 10.37CFQLLDD108 pKa = 5.0LIEE111 pKa = 4.45KK112 pKa = 7.22TQHH115 pKa = 6.15HH116 pKa = 6.55LGDD119 pKa = 3.67RR120 pKa = 11.84DD121 pKa = 3.52FHH123 pKa = 6.7LVRR126 pKa = 11.84NHH128 pKa = 5.51WRR130 pKa = 11.84GCCRR134 pKa = 11.84NCYY137 pKa = 10.11SYY139 pKa = 11.33EE140 pKa = 4.0GG141 pKa = 3.63

Molecular weight: 16.39 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2447

94

663

349.6

39.27

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.885 ± 0.529

2.411 ± 0.779

6.334 ± 0.447

6.253 ± 0.617

4.986 ± 0.663

5.599 ± 0.661

2.166 ± 0.359

5.149 ± 0.731

5.353 ± 0.852

10.012 ± 0.817

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.512 ± 0.42

5.313 ± 0.282

5.885 ± 1.025

3.269 ± 0.416

4.904 ± 0.688

7.601 ± 0.579

6.457 ± 0.742

6.498 ± 0.403

1.389 ± 0.228

3.024 ± 0.467
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski