Amino acid dipepetide frequency for Beihai barnacle virus 9

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.81AlaAla: 9.81 ± 2.222
1.226AlaCys: 1.226 ± 0.683
3.066AlaAsp: 3.066 ± 0.26
5.825AlaGlu: 5.825 ± 1.507
3.066AlaPhe: 3.066 ± 0.505
6.438AlaGly: 6.438 ± 5.923
2.759AlaHis: 2.759 ± 1.03
2.759AlaIle: 2.759 ± 1.717
3.372AlaLys: 3.372 ± 1.345
11.036AlaLeu: 11.036 ± 0.652
1.839AlaMet: 1.839 ± 1.576
2.759AlaAsn: 2.759 ± 0.956
4.905AlaPro: 4.905 ± 0.497
3.066AlaGln: 3.066 ± 0.505
7.051AlaArg: 7.051 ± 0.632
6.438AlaSer: 6.438 ± 1.334
4.598AlaThr: 4.598 ± 0.622
6.131AlaVal: 6.131 ± 1.166
0.613AlaTrp: 0.613 ± 0.525
4.598AlaTyr: 4.598 ± 1.523
0.0AlaXaa: 0.0 ± 0.0
Cys
1.533CysAla: 1.533 ± 0.643
0.613CysCys: 0.613 ± 0.341
2.146CysAsp: 2.146 ± 0.976
0.92CysGlu: 0.92 ± 0.512
1.533CysPhe: 1.533 ± 0.643
1.533CysGly: 1.533 ± 0.7
0.307CysHis: 0.307 ± 0.171
0.307CysIle: 0.307 ± 0.43
0.92CysLys: 0.92 ± 0.512
3.066CysLeu: 3.066 ± 1.289
0.307CysMet: 0.307 ± 0.171
0.613CysAsn: 0.613 ± 0.341
0.92CysPro: 0.92 ± 0.462
1.226CysGln: 1.226 ± 0.681
0.613CysArg: 0.613 ± 0.341
0.92CysSer: 0.92 ± 0.324
1.839CysThr: 1.839 ± 0.648
0.307CysVal: 0.307 ± 0.171
0.307CysTrp: 0.307 ± 0.63
0.92CysTyr: 0.92 ± 0.512
0.0CysXaa: 0.0 ± 0.0
Asp
3.679AspAla: 3.679 ± 1.712
1.839AspCys: 1.839 ± 1.022
1.839AspAsp: 1.839 ± 0.923
3.679AspGlu: 3.679 ± 0.278
1.226AspPhe: 1.226 ± 0.683
1.226AspGly: 1.226 ± 0.681
1.839AspHis: 1.839 ± 0.538
3.066AspIle: 3.066 ± 0.26
0.92AspLys: 0.92 ± 0.512
7.051AspLeu: 7.051 ± 1.377
1.533AspMet: 1.533 ± 0.508
0.613AspAsn: 0.613 ± 0.341
3.372AspPro: 3.372 ± 0.819
0.92AspGln: 0.92 ± 0.324
5.518AspArg: 5.518 ± 0.599
3.985AspSer: 3.985 ± 1.45
1.533AspThr: 1.533 ± 0.7
2.146AspVal: 2.146 ± 0.697
0.307AspTrp: 0.307 ± 0.171
1.226AspTyr: 1.226 ± 0.683
0.0AspXaa: 0.0 ± 0.0
Glu
6.438GluAla: 6.438 ± 1.705
0.613GluCys: 0.613 ± 0.341
4.292GluAsp: 4.292 ± 1.957
3.985GluGlu: 3.985 ± 0.889
2.759GluPhe: 2.759 ± 0.956
4.292GluGly: 4.292 ± 1.327
0.613GluHis: 0.613 ± 0.341
5.212GluIle: 5.212 ± 2.67
3.679GluLys: 3.679 ± 0.278
7.357GluLeu: 7.357 ± 3.014
1.533GluMet: 1.533 ± 0.7
1.839GluAsn: 1.839 ± 0.538
2.759GluPro: 2.759 ± 0.679
2.452GluGln: 2.452 ± 1.557
3.679GluArg: 3.679 ± 0.988
4.598GluSer: 4.598 ± 1.763
3.372GluThr: 3.372 ± 0.37
5.825GluVal: 5.825 ± 3.672
1.226GluTrp: 1.226 ± 0.683
2.759GluTyr: 2.759 ± 0.6
0.0GluXaa: 0.0 ± 0.0
Phe
3.066PheAla: 3.066 ± 0.26
0.613PheCys: 0.613 ± 0.341
1.533PheAsp: 1.533 ± 0.854
2.452PheGlu: 2.452 ± 0.324
0.92PhePhe: 0.92 ± 0.462
3.066PheGly: 3.066 ± 0.583
0.307PheHis: 0.307 ± 0.171
0.613PheIle: 0.613 ± 0.525
0.613PheLys: 0.613 ± 0.341
4.905PheLeu: 4.905 ± 1.124
0.613PheMet: 0.613 ± 0.74
0.0PheAsn: 0.0 ± 0.0
2.452PhePro: 2.452 ± 0.249
1.533PheGln: 1.533 ± 0.7
2.759PheArg: 2.759 ± 1.124
3.372PheSer: 3.372 ± 1.116
1.533PheThr: 1.533 ± 0.508
2.146PheVal: 2.146 ± 0.383
1.839PheTrp: 1.839 ± 0.612
0.307PheTyr: 0.307 ± 0.171
0.0PheXaa: 0.0 ± 0.0
Gly
5.518GlyAla: 5.518 ± 1.985
1.226GlyCys: 1.226 ± 0.681
3.066GlyAsp: 3.066 ± 0.651
3.985GlyGlu: 3.985 ± 1.064
1.839GlyPhe: 1.839 ± 0.538
7.357GlyGly: 7.357 ± 2.165
1.533GlyHis: 1.533 ± 0.508
2.452GlyIle: 2.452 ± 1.557
0.92GlyLys: 0.92 ± 0.324
7.664GlyLeu: 7.664 ± 1.574
1.226GlyMet: 1.226 ± 0.408
0.92GlyAsn: 0.92 ± 0.572
3.985GlyPro: 3.985 ± 1.157
2.452GlyGln: 2.452 ± 1.431
3.985GlyArg: 3.985 ± 1.408
3.066GlySer: 3.066 ± 1.401
2.759GlyThr: 2.759 ± 1.313
5.518GlyVal: 5.518 ± 0.599
1.226GlyTrp: 1.226 ± 0.681
2.452GlyTyr: 2.452 ± 0.249
0.0GlyXaa: 0.0 ± 0.0
His
1.226HisAla: 1.226 ± 0.39
0.307HisCys: 0.307 ± 0.171
1.226HisAsp: 1.226 ± 0.39
0.613HisGlu: 0.613 ± 0.341
1.839HisPhe: 1.839 ± 0.612
1.533HisGly: 1.533 ± 0.512
0.613HisHis: 0.613 ± 0.341
0.92HisIle: 0.92 ± 0.324
0.613HisLys: 0.613 ± 0.525
2.759HisLeu: 2.759 ± 1.124
1.533HisMet: 1.533 ± 0.583
0.307HisAsn: 0.307 ± 0.171
1.533HisPro: 1.533 ± 0.508
1.839HisGln: 1.839 ± 1.024
0.92HisArg: 0.92 ± 0.757
2.146HisSer: 2.146 ± 0.697
0.613HisThr: 0.613 ± 0.341
1.533HisVal: 1.533 ± 0.974
0.92HisTrp: 0.92 ± 0.512
0.307HisTyr: 0.307 ± 0.171
0.0HisXaa: 0.0 ± 0.0
Ile
3.066IleAla: 3.066 ± 1.014
1.533IleCys: 1.533 ± 0.512
3.066IleAsp: 3.066 ± 0.892
3.066IleGlu: 3.066 ± 0.58
2.146IlePhe: 2.146 ± 0.758
1.533IleGly: 1.533 ± 0.508
2.146IleHis: 2.146 ± 0.383
1.839IleIle: 1.839 ± 0.538
2.146IleLys: 2.146 ± 0.697
3.679IleLeu: 3.679 ± 0.553
2.452IleMet: 2.452 ± 1.24
0.613IleAsn: 0.613 ± 0.525
5.212IlePro: 5.212 ± 0.945
1.839IleGln: 1.839 ± 0.877
4.905IleArg: 4.905 ± 0.619
3.066IleSer: 3.066 ± 1.014
1.839IleThr: 1.839 ± 2.295
2.452IleVal: 2.452 ± 0.324
0.307IleTrp: 0.307 ± 0.63
1.533IleTyr: 1.533 ± 0.643
0.0IleXaa: 0.0 ± 0.0
Lys
4.598LysAla: 4.598 ± 1.523
0.307LysCys: 0.307 ± 0.63
1.533LysAsp: 1.533 ± 0.253
3.372LysGlu: 3.372 ± 1.345
0.92LysPhe: 0.92 ± 0.462
3.985LysGly: 3.985 ± 0.382
1.226LysHis: 1.226 ± 0.457
3.985LysIle: 3.985 ± 1.6
0.613LysLys: 0.613 ± 0.341
2.759LysLeu: 2.759 ± 0.6
0.613LysMet: 0.613 ± 0.341
1.839LysAsn: 1.839 ± 0.612
0.613LysPro: 0.613 ± 0.341
1.226LysGln: 1.226 ± 0.683
1.226LysArg: 1.226 ± 0.681
2.452LysSer: 2.452 ± 0.324
2.452LysThr: 2.452 ± 0.802
2.759LysVal: 2.759 ± 0.657
0.613LysTrp: 0.613 ± 0.341
0.613LysTyr: 0.613 ± 0.525
0.0LysXaa: 0.0 ± 0.0
Leu
9.503LeuAla: 9.503 ± 2.047
2.452LeuCys: 2.452 ± 0.962
6.438LeuAsp: 6.438 ± 0.649
8.277LeuGlu: 8.277 ± 1.708
2.146LeuPhe: 2.146 ± 0.803
4.598LeuGly: 4.598 ± 0.766
2.146LeuHis: 2.146 ± 0.383
4.292LeuIle: 4.292 ± 0.918
6.438LeuLys: 6.438 ± 2.274
9.81LeuLeu: 9.81 ± 1.802
3.985LeuMet: 3.985 ± 0.559
2.452LeuAsn: 2.452 ± 0.324
4.598LeuPro: 4.598 ± 1.74
4.292LeuGln: 4.292 ± 1.516
9.197LeuArg: 9.197 ± 1.751
10.73LeuSer: 10.73 ± 2.703
3.985LeuThr: 3.985 ± 0.275
7.664LeuVal: 7.664 ± 2.54
0.307LeuTrp: 0.307 ± 0.171
2.146LeuTyr: 2.146 ± 0.803
0.0LeuXaa: 0.0 ± 0.0
Met
4.598MetAla: 4.598 ± 1.516
0.613MetCys: 0.613 ± 0.341
0.0MetAsp: 0.0 ± 0.0
1.839MetGlu: 1.839 ± 0.139
0.0MetPhe: 0.0 ± 0.0
3.372MetGly: 3.372 ± 1.803
0.0MetHis: 0.0 ± 0.0
1.226MetIle: 1.226 ± 0.39
0.613MetLys: 0.613 ± 0.341
2.452MetLeu: 2.452 ± 1.362
1.226MetMet: 1.226 ± 0.39
0.0MetAsn: 0.0 ± 0.0
0.92MetPro: 0.92 ± 0.572
1.226MetGln: 1.226 ± 0.39
2.146MetArg: 2.146 ± 1.496
3.066MetSer: 3.066 ± 1.552
1.839MetThr: 1.839 ± 0.65
2.759MetVal: 2.759 ± 0.485
0.92MetTrp: 0.92 ± 0.757
0.307MetTyr: 0.307 ± 0.43
0.0MetXaa: 0.0 ± 0.0
Asn
0.307AsnAla: 0.307 ± 0.171
0.613AsnCys: 0.613 ± 0.341
0.307AsnAsp: 0.307 ± 0.171
1.839AsnGlu: 1.839 ± 0.139
1.839AsnPhe: 1.839 ± 0.612
1.226AsnGly: 1.226 ± 0.408
0.92AsnHis: 0.92 ± 0.324
1.839AsnIle: 1.839 ± 0.923
1.226AsnLys: 1.226 ± 0.683
2.452AsnLeu: 2.452 ± 0.962
1.533AsnMet: 1.533 ± 0.508
0.0AsnAsn: 0.0 ± 0.0
1.533AsnPro: 1.533 ± 1.011
0.613AsnGln: 0.613 ± 0.525
2.452AsnArg: 2.452 ± 0.662
2.759AsnSer: 2.759 ± 1.23
0.0AsnThr: 0.0 ± 0.0
2.759AsnVal: 2.759 ± 0.956
0.613AsnTrp: 0.613 ± 0.525
0.613AsnTyr: 0.613 ± 0.861
0.0AsnXaa: 0.0 ± 0.0
Pro
3.679ProAla: 3.679 ± 1.754
1.226ProCys: 1.226 ± 1.184
4.905ProAsp: 4.905 ± 1.605
3.985ProGlu: 3.985 ± 1.809
1.226ProPhe: 1.226 ± 0.457
2.452ProGly: 2.452 ± 0.249
1.533ProHis: 1.533 ± 0.854
0.92ProIle: 0.92 ± 0.324
1.226ProLys: 1.226 ± 0.681
7.971ProLeu: 7.971 ± 2.158
0.92ProMet: 0.92 ± 0.572
2.146ProAsn: 2.146 ± 0.383
3.985ProPro: 3.985 ± 2.219
2.759ProGln: 2.759 ± 0.6
5.212ProArg: 5.212 ± 0.807
4.292ProSer: 4.292 ± 1.605
1.533ProThr: 1.533 ± 0.253
1.839ProVal: 1.839 ± 0.538
0.613ProTrp: 0.613 ± 0.341
0.613ProTyr: 0.613 ± 0.341
0.0ProXaa: 0.0 ± 0.0
Gln
3.066GlnAla: 3.066 ± 2.022
1.533GlnCys: 1.533 ± 0.854
3.372GlnAsp: 3.372 ± 0.52
1.533GlnGlu: 1.533 ± 0.508
0.92GlnPhe: 0.92 ± 0.324
1.533GlnGly: 1.533 ± 0.643
1.226GlnHis: 1.226 ± 0.39
1.533GlnIle: 1.533 ± 0.7
1.533GlnLys: 1.533 ± 0.974
3.066GlnLeu: 3.066 ± 1.187
2.452GlnMet: 2.452 ± 0.914
1.226GlnAsn: 1.226 ± 0.408
0.613GlnPro: 0.613 ± 0.341
0.0GlnGln: 0.0 ± 0.0
1.533GlnArg: 1.533 ± 0.508
2.759GlnSer: 2.759 ± 2.017
2.146GlnThr: 2.146 ± 1.496
2.452GlnVal: 2.452 ± 0.249
0.613GlnTrp: 0.613 ± 0.341
0.613GlnTyr: 0.613 ± 0.341
0.0GlnXaa: 0.0 ± 0.0
Arg
5.825ArgAla: 5.825 ± 1.859
0.613ArgCys: 0.613 ± 0.861
2.759ArgAsp: 2.759 ± 1.03
5.825ArgGlu: 5.825 ± 0.649
1.226ArgPhe: 1.226 ± 0.683
3.985ArgGly: 3.985 ± 0.275
1.226ArgHis: 1.226 ± 0.683
4.598ArgIle: 4.598 ± 1.056
4.598ArgLys: 4.598 ± 0.068
6.438ArgLeu: 6.438 ± 0.869
2.759ArgMet: 2.759 ± 1.973
2.452ArgAsn: 2.452 ± 0.662
3.066ArgPro: 3.066 ± 0.26
1.839ArgGln: 1.839 ± 0.65
6.131ArgArg: 6.131 ± 2.252
7.357ArgSer: 7.357 ± 2.885
3.679ArgThr: 3.679 ± 1.617
6.438ArgVal: 6.438 ± 0.594
1.226ArgTrp: 1.226 ± 0.457
2.452ArgTyr: 2.452 ± 0.324
0.0ArgXaa: 0.0 ± 0.0
Ser
7.357SerAla: 7.357 ± 1.525
1.533SerCys: 1.533 ± 0.508
2.146SerAsp: 2.146 ± 0.182
4.292SerGlu: 4.292 ± 1.394
2.759SerPhe: 2.759 ± 0.679
6.131SerGly: 6.131 ± 1.854
0.92SerHis: 0.92 ± 0.512
2.759SerIle: 2.759 ± 0.188
2.452SerLys: 2.452 ± 0.962
10.73SerLeu: 10.73 ± 1.524
2.146SerMet: 2.146 ± 0.941
1.839SerAsn: 1.839 ± 1.024
4.292SerPro: 4.292 ± 0.364
2.759SerGln: 2.759 ± 0.6
5.825SerArg: 5.825 ± 1.98
6.438SerSer: 6.438 ± 1.334
5.212SerThr: 5.212 ± 1.147
4.292SerVal: 4.292 ± 1.605
1.533SerTrp: 1.533 ± 0.508
3.679SerTyr: 3.679 ± 1.296
0.0SerXaa: 0.0 ± 0.0
Thr
5.518ThrAla: 5.518 ± 1.127
1.533ThrCys: 1.533 ± 0.7
3.066ThrAsp: 3.066 ± 0.583
2.759ThrGlu: 2.759 ± 0.89
1.839ThrPhe: 1.839 ± 1.088
1.839ThrGly: 1.839 ± 1.022
2.452ThrHis: 2.452 ± 0.324
4.905ThrIle: 4.905 ± 0.714
1.533ThrLys: 1.533 ± 0.253
3.985ThrLeu: 3.985 ± 0.858
0.307ThrMet: 0.307 ± 0.171
0.92ThrAsn: 0.92 ± 0.757
0.92ThrPro: 0.92 ± 1.147
0.92ThrGln: 0.92 ± 0.324
2.759ThrArg: 2.759 ± 1.313
3.372ThrSer: 3.372 ± 1.54
2.759ThrThr: 2.759 ± 0.6
4.598ThrVal: 4.598 ± 0.758
0.92ThrTrp: 0.92 ± 0.512
0.92ThrTyr: 0.92 ± 0.324
0.0ThrXaa: 0.0 ± 0.0
Val
6.744ValAla: 6.744 ± 3.002
1.533ValCys: 1.533 ± 0.854
1.533ValAsp: 1.533 ± 0.512
7.664ValGlu: 7.664 ± 1.176
3.679ValPhe: 3.679 ± 1.224
4.292ValGly: 4.292 ± 1.753
0.92ValHis: 0.92 ± 0.512
2.452ValIle: 2.452 ± 0.249
3.372ValLys: 3.372 ± 1.127
4.905ValLeu: 4.905 ± 0.876
1.226ValMet: 1.226 ± 0.408
2.759ValAsn: 2.759 ± 0.956
5.825ValPro: 5.825 ± 0.915
2.146ValGln: 2.146 ± 0.758
4.598ValArg: 4.598 ± 0.497
5.212ValSer: 5.212 ± 0.928
3.372ValThr: 3.372 ± 0.52
2.759ValVal: 2.759 ± 0.89
2.452ValTrp: 2.452 ± 0.781
1.839ValTyr: 1.839 ± 0.139
0.0ValXaa: 0.0 ± 0.0
Trp
3.066TrpAla: 3.066 ± 1.186
0.92TrpCys: 0.92 ± 0.512
0.613TrpAsp: 0.613 ± 0.341
1.533TrpGlu: 1.533 ± 0.854
0.92TrpPhe: 0.92 ± 0.324
0.92TrpGly: 0.92 ± 0.512
0.0TrpHis: 0.0 ± 0.0
0.307TrpIle: 0.307 ± 0.171
0.307TrpLys: 0.307 ± 0.43
0.92TrpLeu: 0.92 ± 0.572
0.613TrpMet: 0.613 ± 0.341
0.92TrpAsn: 0.92 ± 0.462
0.307TrpPro: 0.307 ± 0.171
0.0TrpGln: 0.0 ± 0.0
1.226TrpArg: 1.226 ± 0.683
0.307TrpSer: 0.307 ± 0.171
2.146TrpThr: 2.146 ± 0.98
1.226TrpVal: 1.226 ± 0.457
0.307TrpTrp: 0.307 ± 0.171
0.307TrpTyr: 0.307 ± 0.43
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.759TyrAla: 2.759 ± 1.385
0.0TyrCys: 0.0 ± 0.0
0.613TyrAsp: 0.613 ± 0.525
1.839TyrGlu: 1.839 ± 0.139
1.839TyrPhe: 1.839 ± 1.024
1.839TyrGly: 1.839 ± 1.024
0.92TyrHis: 0.92 ± 0.512
2.452TyrIle: 2.452 ± 0.324
0.613TyrLys: 0.613 ± 0.525
2.452TyrLeu: 2.452 ± 1.362
0.0TyrMet: 0.0 ± 0.0
1.226TyrAsn: 1.226 ± 0.681
1.226TyrPro: 1.226 ± 0.39
0.613TyrGln: 0.613 ± 0.341
2.759TyrArg: 2.759 ± 0.89
2.759TyrSer: 2.759 ± 0.972
0.613TyrThr: 0.613 ± 0.341
3.679TyrVal: 3.679 ± 1.225
0.0TyrTrp: 0.0 ± 0.0
1.226TyrTyr: 1.226 ± 0.457
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (3263 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski