Amino acid dipepetide frequency for Potato latent virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.452AlaAla: 5.452 ± 2.38
1.558AlaCys: 1.558 ± 1.568
1.558AlaAsp: 1.558 ± 1.425
3.115AlaGlu: 3.115 ± 0.993
2.336AlaPhe: 2.336 ± 0.813
3.894AlaGly: 3.894 ± 1.263
2.336AlaHis: 2.336 ± 0.85
5.841AlaIle: 5.841 ± 2.924
7.788AlaLys: 7.788 ± 2.787
6.62AlaLeu: 6.62 ± 4.026
1.947AlaMet: 1.947 ± 1.126
4.673AlaAsn: 4.673 ± 2.28
2.336AlaPro: 2.336 ± 1.355
2.336AlaGln: 2.336 ± 0.662
3.115AlaArg: 3.115 ± 1.365
5.062AlaSer: 5.062 ± 1.513
2.726AlaThr: 2.726 ± 1.43
8.567AlaVal: 8.567 ± 4.141
0.389AlaTrp: 0.389 ± 0.212
1.947AlaTyr: 1.947 ± 1.061
0.0AlaXaa: 0.0 ± 0.0
Cys
2.336CysAla: 2.336 ± 0.85
0.389CysCys: 0.389 ± 0.212
0.389CysAsp: 0.389 ± 0.212
0.779CysGlu: 0.779 ± 1.096
2.336CysPhe: 2.336 ± 1.132
1.168CysGly: 1.168 ± 0.944
1.168CysHis: 1.168 ± 1.669
2.336CysIle: 2.336 ± 1.098
0.389CysLys: 0.389 ± 0.212
1.168CysLeu: 1.168 ± 1.486
0.779CysMet: 0.779 ± 0.713
1.168CysAsn: 1.168 ± 2.274
0.389CysPro: 0.389 ± 0.787
0.389CysGln: 0.389 ± 0.212
3.505CysArg: 3.505 ± 0.93
3.505CysSer: 3.505 ± 1.331
1.168CysThr: 1.168 ± 0.637
2.726CysVal: 2.726 ± 1.142
0.0CysTrp: 0.0 ± 0.0
1.168CysTyr: 1.168 ± 1.042
0.0CysXaa: 0.0 ± 0.0
Asp
1.558AspAla: 1.558 ± 0.589
1.168AspCys: 1.168 ± 0.637
1.558AspAsp: 1.558 ± 1.254
4.283AspGlu: 4.283 ± 1.253
1.947AspPhe: 1.947 ± 0.678
3.115AspGly: 3.115 ± 0.892
0.779AspHis: 0.779 ± 0.424
2.336AspIle: 2.336 ± 1.396
3.115AspLys: 3.115 ± 1.243
3.894AspLeu: 3.894 ± 1.079
1.558AspMet: 1.558 ± 0.589
2.726AspAsn: 2.726 ± 1.221
2.336AspPro: 2.336 ± 1.228
1.168AspGln: 1.168 ± 0.57
1.558AspArg: 1.558 ± 0.589
2.726AspSer: 2.726 ± 1.723
0.389AspThr: 0.389 ± 0.212
2.726AspVal: 2.726 ± 1.142
0.779AspTrp: 0.779 ± 0.627
1.947AspTyr: 1.947 ± 0.906
0.0AspXaa: 0.0 ± 0.0
Glu
7.009GluAla: 7.009 ± 2.135
1.558GluCys: 1.558 ± 0.849
2.726GluAsp: 2.726 ± 1.486
7.788GluGlu: 7.788 ± 1.911
3.115GluPhe: 3.115 ± 1.317
7.009GluGly: 7.009 ± 2.209
0.0GluHis: 0.0 ± 0.0
4.673GluIle: 4.673 ± 1.513
3.505GluLys: 3.505 ± 0.921
10.125GluLeu: 10.125 ± 4.827
1.947GluMet: 1.947 ± 1.126
3.505GluAsn: 3.505 ± 0.921
2.726GluPro: 2.726 ± 1.979
3.505GluGln: 3.505 ± 1.345
3.894GluArg: 3.894 ± 1.356
4.283GluSer: 4.283 ± 1.149
1.558GluThr: 1.558 ± 0.784
3.894GluVal: 3.894 ± 1.915
0.389GluTrp: 0.389 ± 0.212
3.115GluTyr: 3.115 ± 0.788
0.0GluXaa: 0.0 ± 0.0
Phe
6.62PheAla: 6.62 ± 1.413
1.168PheCys: 1.168 ± 0.637
1.558PheAsp: 1.558 ± 1.254
6.62PheGlu: 6.62 ± 2.228
1.168PhePhe: 1.168 ± 0.57
2.726PheGly: 2.726 ± 2.904
0.779PheHis: 0.779 ± 0.713
2.336PheIle: 2.336 ± 1.132
3.505PheLys: 3.505 ± 1.502
4.283PheLeu: 4.283 ± 1.888
1.168PheMet: 1.168 ± 0.637
3.115PheAsn: 3.115 ± 1.087
1.947PhePro: 1.947 ± 0.846
1.558PheGln: 1.558 ± 0.589
2.336PheArg: 2.336 ± 1.063
3.115PheSer: 3.115 ± 0.879
1.947PheThr: 1.947 ± 1.062
2.726PheVal: 2.726 ± 1.429
0.0PheTrp: 0.0 ± 0.0
1.168PheTyr: 1.168 ± 0.637
0.0PheXaa: 0.0 ± 0.0
Gly
5.062GlyAla: 5.062 ± 0.845
1.168GlyCys: 1.168 ± 0.698
3.894GlyAsp: 3.894 ± 2.067
6.62GlyGlu: 6.62 ± 1.155
2.726GlyPhe: 2.726 ± 2.112
2.726GlyGly: 2.726 ± 1.4
0.0GlyHis: 0.0 ± 0.0
1.947GlyIle: 1.947 ± 1.062
7.399GlyLys: 7.399 ± 1.465
3.894GlyLeu: 3.894 ± 2.241
0.389GlyMet: 0.389 ± 1.186
0.779GlyAsn: 0.779 ± 0.627
1.168GlyPro: 1.168 ± 0.916
1.168GlyGln: 1.168 ± 2.038
3.894GlyArg: 3.894 ± 2.296
2.726GlySer: 2.726 ± 1.486
4.673GlyThr: 4.673 ± 1.596
8.178GlyVal: 8.178 ± 1.962
0.779GlyTrp: 0.779 ± 0.713
1.558GlyTyr: 1.558 ± 0.849
0.0GlyXaa: 0.0 ± 0.0
His
0.779HisAla: 0.779 ± 0.424
0.779HisCys: 0.779 ± 0.983
0.779HisAsp: 0.779 ± 0.424
0.389HisGlu: 0.389 ± 0.212
0.779HisPhe: 0.779 ± 0.424
1.168HisGly: 1.168 ± 1.135
0.389HisHis: 0.389 ± 0.212
1.558HisIle: 1.558 ± 0.746
0.779HisLys: 0.779 ± 0.627
2.726HisLeu: 2.726 ± 1.486
0.779HisMet: 0.779 ± 1.132
1.947HisAsn: 1.947 ± 1.179
0.389HisPro: 0.389 ± 0.212
0.389HisGln: 0.389 ± 0.742
1.558HisArg: 1.558 ± 1.113
3.505HisSer: 3.505 ± 2.111
0.779HisThr: 0.779 ± 0.424
0.779HisVal: 0.779 ± 0.424
0.0HisTrp: 0.0 ± 0.0
1.947HisTyr: 1.947 ± 1.062
0.0HisXaa: 0.0 ± 0.0
Ile
5.062IleAla: 5.062 ± 1.076
0.779IleCys: 0.779 ± 0.424
2.726IleAsp: 2.726 ± 0.696
4.673IleGlu: 4.673 ± 1.482
2.726IlePhe: 2.726 ± 0.696
3.505IleGly: 3.505 ± 2.129
1.168IleHis: 1.168 ± 0.637
1.558IleIle: 1.558 ± 1.319
5.452IleLys: 5.452 ± 0.976
4.283IleLeu: 4.283 ± 3.093
0.779IleMet: 0.779 ± 0.424
1.558IleAsn: 1.558 ± 0.849
1.558IlePro: 1.558 ± 1.643
3.115IleGln: 3.115 ± 0.879
2.726IleArg: 2.726 ± 1.692
0.779IleSer: 0.779 ± 1.491
4.673IleThr: 4.673 ± 1.223
5.062IleVal: 5.062 ± 3.577
0.779IleTrp: 0.779 ± 0.424
2.336IleTyr: 2.336 ± 0.927
0.0IleXaa: 0.0 ± 0.0
Lys
5.062LysAla: 5.062 ± 1.944
0.0LysCys: 0.0 ± 0.0
1.947LysAsp: 1.947 ± 1.061
5.062LysGlu: 5.062 ± 2.759
2.726LysPhe: 2.726 ± 1.236
5.062LysGly: 5.062 ± 1.785
0.779LysHis: 0.779 ± 0.424
3.115LysIle: 3.115 ± 1.961
3.894LysLys: 3.894 ± 2.122
8.567LysLeu: 8.567 ± 2.463
1.558LysMet: 1.558 ± 0.583
1.947LysAsn: 1.947 ± 1.061
4.283LysPro: 4.283 ± 2.1
2.336LysGln: 2.336 ± 0.813
5.062LysArg: 5.062 ± 1.638
5.452LysSer: 5.452 ± 0.903
2.726LysThr: 2.726 ± 1.142
5.452LysVal: 5.452 ± 2.285
0.389LysTrp: 0.389 ± 0.212
2.336LysTyr: 2.336 ± 0.984
0.0LysXaa: 0.0 ± 0.0
Leu
7.788LeuAla: 7.788 ± 3.116
3.115LeuCys: 3.115 ± 1.317
7.399LeuAsp: 7.399 ± 1.139
7.399LeuGlu: 7.399 ± 1.718
3.894LeuPhe: 3.894 ± 1.54
6.231LeuGly: 6.231 ± 2.169
2.336LeuHis: 2.336 ± 0.85
5.452LeuIle: 5.452 ± 1.334
8.567LeuLys: 8.567 ± 2.276
8.956LeuLeu: 8.956 ± 4.051
2.336LeuMet: 2.336 ± 1.273
3.894LeuAsn: 3.894 ± 2.206
3.894LeuPro: 3.894 ± 1.109
1.947LeuGln: 1.947 ± 1.344
4.283LeuArg: 4.283 ± 0.784
5.452LeuSer: 5.452 ± 2.453
3.894LeuThr: 3.894 ± 1.295
7.399LeuVal: 7.399 ± 1.576
0.0LeuTrp: 0.0 ± 0.0
1.947LeuTyr: 1.947 ± 0.846
0.0LeuXaa: 0.0 ± 0.0
Met
2.726MetAla: 2.726 ± 1.04
0.779MetCys: 0.779 ± 0.424
1.168MetAsp: 1.168 ± 0.916
0.779MetGlu: 0.779 ± 0.627
0.779MetPhe: 0.779 ± 1.096
2.336MetGly: 2.336 ± 1.063
0.0MetHis: 0.0 ± 0.0
1.558MetIle: 1.558 ± 0.746
0.389MetLys: 0.389 ± 0.212
1.947MetLeu: 1.947 ± 0.678
1.558MetMet: 1.558 ± 0.849
0.389MetAsn: 0.389 ± 0.212
0.389MetPro: 0.389 ± 1.064
1.947MetGln: 1.947 ± 1.062
3.115MetArg: 3.115 ± 1.156
0.779MetSer: 0.779 ± 0.983
1.558MetThr: 1.558 ± 0.849
0.389MetVal: 0.389 ± 0.742
0.0MetTrp: 0.0 ± 0.0
0.779MetTyr: 0.779 ± 1.096
0.0MetXaa: 0.0 ± 0.0
Asn
1.947AsnAla: 1.947 ± 0.694
2.336AsnCys: 2.336 ± 1.646
2.336AsnAsp: 2.336 ± 0.813
2.336AsnGlu: 2.336 ± 1.881
2.336AsnPhe: 2.336 ± 0.813
1.558AsnGly: 1.558 ± 1.223
1.558AsnHis: 1.558 ± 0.589
1.947AsnIle: 1.947 ± 1.277
1.558AsnLys: 1.558 ± 1.76
3.894AsnLeu: 3.894 ± 1.403
0.779AsnMet: 0.779 ± 1.28
1.558AsnAsn: 1.558 ± 0.784
0.779AsnPro: 0.779 ± 0.627
0.389AsnGln: 0.389 ± 0.787
2.336AsnArg: 2.336 ± 0.813
4.283AsnSer: 4.283 ± 1.716
2.336AsnThr: 2.336 ± 0.813
4.283AsnVal: 4.283 ± 1.339
0.779AsnTrp: 0.779 ± 0.424
1.947AsnTyr: 1.947 ± 1.061
0.0AsnXaa: 0.0 ± 0.0
Pro
2.726ProAla: 2.726 ± 1.433
0.779ProCys: 0.779 ± 0.424
2.726ProAsp: 2.726 ± 0.845
4.283ProGlu: 4.283 ± 1.325
1.558ProPhe: 1.558 ± 0.746
1.558ProGly: 1.558 ± 1.113
1.168ProHis: 1.168 ± 1.135
1.947ProIle: 1.947 ± 1.277
1.168ProLys: 1.168 ± 2.155
3.505ProLeu: 3.505 ± 1.844
0.779ProMet: 0.779 ± 1.626
2.726ProAsn: 2.726 ± 2.098
3.505ProPro: 3.505 ± 3.135
0.779ProGln: 0.779 ± 0.424
0.779ProArg: 0.779 ± 0.424
2.726ProSer: 2.726 ± 1.801
3.115ProThr: 3.115 ± 1.785
1.947ProVal: 1.947 ± 1.358
0.779ProTrp: 0.779 ± 0.983
1.558ProTyr: 1.558 ± 0.849
0.0ProXaa: 0.0 ± 0.0
Gln
2.336GlnAla: 2.336 ± 1.14
0.389GlnCys: 0.389 ± 0.212
1.558GlnAsp: 1.558 ± 0.863
2.726GlnGlu: 2.726 ± 1.486
1.168GlnPhe: 1.168 ± 0.698
0.779GlnGly: 0.779 ± 0.424
0.779GlnHis: 0.779 ± 0.424
1.947GlnIle: 1.947 ± 0.678
1.168GlnLys: 1.168 ± 0.57
2.726GlnLeu: 2.726 ± 1.142
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
1.947GlnPro: 1.947 ± 2.584
0.779GlnGln: 0.779 ± 0.424
1.558GlnArg: 1.558 ± 1.004
2.336GlnSer: 2.336 ± 0.813
1.947GlnThr: 1.947 ± 1.061
2.336GlnVal: 2.336 ± 0.662
0.389GlnTrp: 0.389 ± 0.742
0.389GlnTyr: 0.389 ± 0.212
0.0GlnXaa: 0.0 ± 0.0
Arg
3.115ArgAla: 3.115 ± 1.374
2.726ArgCys: 2.726 ± 4.903
3.505ArgAsp: 3.505 ± 2.425
1.947ArgGlu: 1.947 ± 1.061
5.841ArgPhe: 5.841 ± 1.273
2.726ArgGly: 2.726 ± 1.123
2.336ArgHis: 2.336 ± 1.396
2.336ArgIle: 2.336 ± 1.639
2.726ArgLys: 2.726 ± 1.142
6.62ArgLeu: 6.62 ± 2.622
1.947ArgMet: 1.947 ± 1.061
2.726ArgAsn: 2.726 ± 1.801
1.558ArgPro: 1.558 ± 2.096
0.389ArgGln: 0.389 ± 0.212
5.062ArgArg: 5.062 ± 4.11
4.673ArgSer: 4.673 ± 0.887
1.558ArgThr: 1.558 ± 1.568
3.894ArgVal: 3.894 ± 1.024
1.168ArgTrp: 1.168 ± 0.637
2.726ArgTyr: 2.726 ± 1.486
0.0ArgXaa: 0.0 ± 0.0
Ser
3.115SerAla: 3.115 ± 1.156
1.947SerCys: 1.947 ± 0.878
2.336SerAsp: 2.336 ± 0.662
4.673SerGlu: 4.673 ± 1.954
3.894SerPhe: 3.894 ± 1.177
3.115SerGly: 3.115 ± 1.366
1.558SerHis: 1.558 ± 1.03
3.115SerIle: 3.115 ± 0.879
5.062SerLys: 5.062 ± 2.288
6.62SerLeu: 6.62 ± 3.34
1.947SerMet: 1.947 ± 1.062
1.947SerAsn: 1.947 ± 1.179
3.115SerPro: 3.115 ± 1.243
1.558SerGln: 1.558 ± 0.589
6.231SerArg: 6.231 ± 1.363
6.231SerSer: 6.231 ± 2.612
4.283SerThr: 4.283 ± 2.095
5.841SerVal: 5.841 ± 4.187
1.168SerTrp: 1.168 ± 0.698
1.558SerTyr: 1.558 ± 0.849
0.0SerXaa: 0.0 ± 0.0
Thr
3.115ThrAla: 3.115 ± 0.993
0.779ThrCys: 0.779 ± 1.789
0.389ThrAsp: 0.389 ± 0.212
3.894ThrGlu: 3.894 ± 1.203
5.062ThrPhe: 5.062 ± 2.288
3.505ThrGly: 3.505 ± 1.818
2.336ThrHis: 2.336 ± 0.662
2.336ThrIle: 2.336 ± 0.85
3.505ThrLys: 3.505 ± 1.946
3.505ThrLeu: 3.505 ± 1.452
1.558ThrMet: 1.558 ± 0.695
1.558ThrAsn: 1.558 ± 0.589
1.947ThrPro: 1.947 ± 0.906
1.168ThrGln: 1.168 ± 0.637
3.115ThrArg: 3.115 ± 2.221
3.894ThrSer: 3.894 ± 1.227
1.947ThrThr: 1.947 ± 0.846
1.558ThrVal: 1.558 ± 0.746
0.389ThrTrp: 0.389 ± 0.212
1.947ThrTyr: 1.947 ± 1.031
0.0ThrXaa: 0.0 ± 0.0
Val
5.452ValAla: 5.452 ± 2.317
3.894ValCys: 3.894 ± 1.54
1.947ValAsp: 1.947 ± 1.061
5.841ValGlu: 5.841 ± 1.472
3.505ValPhe: 3.505 ± 1.441
5.452ValGly: 5.452 ± 3.12
2.336ValHis: 2.336 ± 0.662
5.452ValIle: 5.452 ± 2.215
4.673ValLys: 4.673 ± 1.297
6.231ValLeu: 6.231 ± 1.375
0.389ValMet: 0.389 ± 0.212
3.115ValAsn: 3.115 ± 1.419
3.505ValPro: 3.505 ± 1.019
1.558ValGln: 1.558 ± 0.849
4.283ValArg: 4.283 ± 1.245
6.62ValSer: 6.62 ± 1.786
2.726ValThr: 2.726 ± 1.979
6.231ValVal: 6.231 ± 2.028
0.779ValTrp: 0.779 ± 0.627
3.505ValTyr: 3.505 ± 2.491
0.0ValXaa: 0.0 ± 0.0
Trp
0.779TrpAla: 0.779 ± 1.287
0.779TrpCys: 0.779 ± 0.424
0.389TrpAsp: 0.389 ± 0.212
0.389TrpGlu: 0.389 ± 0.212
0.779TrpPhe: 0.779 ± 0.424
0.389TrpGly: 0.389 ± 0.212
0.0TrpHis: 0.0 ± 0.0
1.168TrpIle: 1.168 ± 0.698
0.0TrpLys: 0.0 ± 0.0
0.779TrpLeu: 0.779 ± 0.424
0.389TrpMet: 0.389 ± 0.212
1.947TrpAsn: 1.947 ± 1.179
0.0TrpPro: 0.0 ± 0.0
0.389TrpGln: 0.389 ± 0.212
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.779TrpThr: 0.779 ± 0.713
0.389TrpVal: 0.389 ± 0.212
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.558TyrAla: 1.558 ± 0.746
1.168TyrCys: 1.168 ± 0.916
0.779TyrAsp: 0.779 ± 0.424
2.726TyrGlu: 2.726 ± 1.236
1.168TyrPhe: 1.168 ± 0.698
2.726TyrGly: 2.726 ± 1.422
0.389TyrHis: 0.389 ± 0.212
2.336TyrIle: 2.336 ± 1.273
3.115TyrLys: 3.115 ± 1.365
5.841TyrLeu: 5.841 ± 2.016
0.389TyrMet: 0.389 ± 0.212
0.389TyrAsn: 0.389 ± 0.212
2.336TyrPro: 2.336 ± 1.132
0.389TyrGln: 0.389 ± 0.212
1.168TyrArg: 1.168 ± 0.637
1.168TyrSer: 1.168 ± 1.199
2.726TyrThr: 2.726 ± 0.845
3.115TyrVal: 3.115 ± 0.788
0.389TyrTrp: 0.389 ± 0.212
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2569 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski