Amino acid dipepetide frequency for Ophiocordyceps polyrhachis-furcata BCC 54312

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.668AlaAla: 11.668 ± 0.097	1.232AlaCys: 1.232 ± 0.02	5.15AlaAsp: 5.15 ± 0.038	5.289AlaGlu: 5.289 ± 0.046	3.085AlaPhe: 3.085 ± 0.031	6.375AlaGly: 6.375 ± 0.042	1.819AlaHis: 1.819 ± 0.021	3.759AlaIle: 3.759 ± 0.036	3.974AlaLys: 3.974 ± 0.036	8.158AlaLeu: 8.158 ± 0.053	2.202AlaMet: 2.202 ± 0.025	2.68AlaAsn: 2.68 ± 0.025	4.932AlaPro: 4.932 ± 0.043	3.225AlaGln: 3.225 ± 0.03	6.167AlaArg: 6.167 ± 0.048	8.079AlaSer: 8.079 ± 0.059	5.249AlaThr: 5.249 ± 0.039	6.639AlaVal: 6.639 ± 0.052	1.164AlaTrp: 1.164 ± 0.018	2.058AlaTyr: 2.058 ± 0.026	0.0AlaXaa: 0.0 ± 0.0
Cys	1.035CysAla: 1.035 ± 0.017	0.299CysCys: 0.299 ± 0.01	0.747CysAsp: 0.747 ± 0.013	0.607CysGlu: 0.607 ± 0.014	0.592CysPhe: 0.592 ± 0.013	1.067CysGly: 1.067 ± 0.022	0.404CysHis: 0.404 ± 0.011	0.641CysIle: 0.641 ± 0.014	0.49CysLys: 0.49 ± 0.013	1.516CysLeu: 1.516 ± 0.021	0.286CysMet: 0.286 ± 0.008	0.452CysAsn: 0.452 ± 0.011	0.779CysPro: 0.779 ± 0.019	0.489CysGln: 0.489 ± 0.012	1.081CysArg: 1.081 ± 0.019	1.091CysSer: 1.091 ± 0.016	0.649CysThr: 0.649 ± 0.012	0.874CysVal: 0.874 ± 0.018	0.205CysTrp: 0.205 ± 0.007	0.378CysTyr: 0.378 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	5.535AspAla: 5.535 ± 0.038	0.703AspCys: 0.703 ± 0.011	6.552AspAsp: 6.552 ± 0.093	4.804AspGlu: 4.804 ± 0.047	2.219AspPhe: 2.219 ± 0.022	4.993AspGly: 4.993 ± 0.048	1.238AspHis: 1.238 ± 0.017	2.317AspIle: 2.317 ± 0.028	2.494AspLys: 2.494 ± 0.027	4.884AspLeu: 4.884 ± 0.035	1.362AspMet: 1.362 ± 0.018	1.75AspAsn: 1.75 ± 0.024	2.901AspPro: 2.901 ± 0.027	1.885AspGln: 1.885 ± 0.024	3.736AspArg: 3.736 ± 0.034	4.049AspSer: 4.049 ± 0.039	2.401AspThr: 2.401 ± 0.022	4.138AspVal: 4.138 ± 0.034	0.848AspTrp: 0.848 ± 0.015	1.413AspTyr: 1.413 ± 0.021	0.0AspXaa: 0.0 ± 0.0
Glu	6.24GluAla: 6.24 ± 0.055	0.593GluCys: 0.593 ± 0.012	3.793GluAsp: 3.793 ± 0.038	5.402GluGlu: 5.402 ± 0.068	1.569GluPhe: 1.569 ± 0.021	3.6GluGly: 3.6 ± 0.034	1.178GluHis: 1.178 ± 0.017	2.085GluIle: 2.085 ± 0.024	3.334GluLys: 3.334 ± 0.036	4.875GluLeu: 4.875 ± 0.036	1.49GluMet: 1.49 ± 0.021	1.656GluAsn: 1.656 ± 0.018	2.758GluPro: 2.758 ± 0.028	2.231GluGln: 2.231 ± 0.027	4.024GluArg: 4.024 ± 0.041	3.89GluSer: 3.89 ± 0.035	3.137GluThr: 3.137 ± 0.032	3.218GluVal: 3.218 ± 0.032	0.749GluTrp: 0.749 ± 0.014	1.284GluTyr: 1.284 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	2.888PheAla: 2.888 ± 0.029	0.654PheCys: 0.654 ± 0.013	2.128PheAsp: 2.128 ± 0.023	1.765PheGlu: 1.765 ± 0.023	1.848PhePhe: 1.848 ± 0.031	2.475PheGly: 2.475 ± 0.026	0.879PheHis: 0.879 ± 0.014	1.519PheIle: 1.519 ± 0.022	1.282PheLys: 1.282 ± 0.019	3.539PheLeu: 3.539 ± 0.033	0.666PheMet: 0.666 ± 0.014	1.268PheAsn: 1.268 ± 0.019	1.935PhePro: 1.935 ± 0.024	1.205PheGln: 1.205 ± 0.019	2.261PheArg: 2.261 ± 0.021	2.985PheSer: 2.985 ± 0.032	1.753PheThr: 1.753 ± 0.023	2.42PheVal: 2.42 ± 0.025	0.55PheTrp: 0.55 ± 0.013	0.983PheTyr: 0.983 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	5.384GlyAla: 5.384 ± 0.046	1.012GlyCys: 1.012 ± 0.016	3.915GlyAsp: 3.915 ± 0.038	3.682GlyGlu: 3.682 ± 0.032	2.601GlyPhe: 2.601 ± 0.031	7.34GlyGly: 7.34 ± 0.088	1.816GlyHis: 1.816 ± 0.025	2.988GlyIle: 2.988 ± 0.027	3.277GlyLys: 3.277 ± 0.028	6.205GlyLeu: 6.205 ± 0.043	1.427GlyMet: 1.427 ± 0.021	2.2GlyAsn: 2.2 ± 0.028	4.007GlyPro: 4.007 ± 0.039	2.583GlyGln: 2.583 ± 0.029	5.429GlyArg: 5.429 ± 0.048	5.849GlySer: 5.849 ± 0.053	3.53GlyThr: 3.53 ± 0.032	4.225GlyVal: 4.225 ± 0.04	1.107GlyTrp: 1.107 ± 0.019	2.11GlyTyr: 2.11 ± 0.031	0.0GlyXaa: 0.0 ± 0.0
His	1.895HisAla: 1.895 ± 0.021	0.378HisCys: 0.378 ± 0.01	1.473HisAsp: 1.473 ± 0.02	1.21HisGlu: 1.21 ± 0.017	0.842HisPhe: 0.842 ± 0.014	1.819HisGly: 1.819 ± 0.023	1.359HisHis: 1.359 ± 0.043	0.978HisIle: 0.978 ± 0.015	0.813HisLys: 0.813 ± 0.013	2.427HisLeu: 2.427 ± 0.026	0.488HisMet: 0.488 ± 0.012	0.759HisAsn: 0.759 ± 0.015	1.645HisPro: 1.645 ± 0.024	1.113HisGln: 1.113 ± 0.022	1.79HisArg: 1.79 ± 0.024	1.736HisSer: 1.736 ± 0.022	1.068HisThr: 1.068 ± 0.014	1.748HisVal: 1.748 ± 0.019	0.323HisTrp: 0.323 ± 0.009	0.633HisTyr: 0.633 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	3.543IleAla: 3.543 ± 0.031	0.69IleCys: 0.69 ± 0.013	2.526IleAsp: 2.526 ± 0.026	2.215IleGlu: 2.215 ± 0.027	1.569IlePhe: 1.569 ± 0.023	2.675IleGly: 2.675 ± 0.027	1.051IleHis: 1.051 ± 0.016	2.004IleIle: 2.004 ± 0.029	1.861IleLys: 1.861 ± 0.024	3.635IleLeu: 3.635 ± 0.033	0.926IleMet: 0.926 ± 0.015	1.432IleAsn: 1.432 ± 0.022	2.314IlePro: 2.314 ± 0.025	1.474IleGln: 1.474 ± 0.02	2.972IleArg: 2.972 ± 0.029	3.157IleSer: 3.157 ± 0.032	2.095IleThr: 2.095 ± 0.022	2.806IleVal: 2.806 ± 0.03	0.552IleTrp: 0.552 ± 0.012	1.083IleTyr: 1.083 ± 0.019	0.0IleXaa: 0.0 ± 0.0
Lys	4.326LysAla: 4.326 ± 0.041	0.463LysCys: 0.463 ± 0.013	2.492LysAsp: 2.492 ± 0.029	2.801LysGlu: 2.801 ± 0.033	1.163LysPhe: 1.163 ± 0.019	2.669LysGly: 2.669 ± 0.027	1.007LysHis: 1.007 ± 0.016	1.744LysIle: 1.744 ± 0.024	3.435LysLys: 3.435 ± 0.045	3.847LysLeu: 3.847 ± 0.034	1.062LysMet: 1.062 ± 0.016	1.365LysAsn: 1.365 ± 0.02	2.632LysPro: 2.632 ± 0.03	1.725LysGln: 1.725 ± 0.025	3.454LysArg: 3.454 ± 0.032	3.078LysSer: 3.078 ± 0.028	2.909LysThr: 2.909 ± 0.033	2.542LysVal: 2.542 ± 0.027	0.552LysTrp: 0.552 ± 0.012	1.113LysTyr: 1.113 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	8.525LeuAla: 8.525 ± 0.049	1.388LeuCys: 1.388 ± 0.019	5.352LeuAsp: 5.352 ± 0.036	5.113LeuGlu: 5.113 ± 0.039	3.418LeuPhe: 3.418 ± 0.03	5.943LeuGly: 5.943 ± 0.042	2.214LeuHis: 2.214 ± 0.024	3.515LeuIle: 3.515 ± 0.035	3.625LeuLys: 3.625 ± 0.032	9.28LeuLeu: 9.28 ± 0.065	1.828LeuMet: 1.828 ± 0.023	2.604LeuAsn: 2.604 ± 0.029	5.956LeuPro: 5.956 ± 0.04	3.669LeuGln: 3.669 ± 0.034	6.933LeuArg: 6.933 ± 0.049	7.571LeuSer: 7.571 ± 0.043	4.855LeuThr: 4.855 ± 0.037	6.04LeuVal: 6.04 ± 0.045	1.16LeuTrp: 1.16 ± 0.02	2.372LeuTyr: 2.372 ± 0.027	0.0LeuXaa: 0.0 ± 0.0
Met	2.485MetAla: 2.485 ± 0.025	0.248MetCys: 0.248 ± 0.008	1.307MetAsp: 1.307 ± 0.017	1.243MetGlu: 1.243 ± 0.017	0.621MetPhe: 0.621 ± 0.013	1.443MetGly: 1.443 ± 0.018	0.486MetHis: 0.486 ± 0.01	0.816MetIle: 0.816 ± 0.015	0.903MetLys: 0.903 ± 0.014	1.983MetLeu: 1.983 ± 0.023	0.687MetMet: 0.687 ± 0.013	0.64MetAsn: 0.64 ± 0.012	1.416MetPro: 1.416 ± 0.023	0.819MetGln: 0.819 ± 0.015	1.494MetArg: 1.494 ± 0.018	1.785MetSer: 1.785 ± 0.023	1.531MetThr: 1.531 ± 0.021	1.328MetVal: 1.328 ± 0.021	0.232MetTrp: 0.232 ± 0.007	0.466MetTyr: 0.466 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	2.604AsnAla: 2.604 ± 0.028	0.401AsnCys: 0.401 ± 0.01	1.747AsnAsp: 1.747 ± 0.024	1.608AsnGlu: 1.608 ± 0.02	1.105AsnPhe: 1.105 ± 0.017	2.438AsnGly: 2.438 ± 0.029	0.849AsnHis: 0.849 ± 0.015	1.414AsnIle: 1.414 ± 0.018	1.533AsnLys: 1.533 ± 0.022	2.759AsnLeu: 2.759 ± 0.026	0.736AsnMet: 0.736 ± 0.012	1.559AsnAsn: 1.559 ± 0.035	1.942AsnPro: 1.942 ± 0.023	1.126AsnGln: 1.126 ± 0.017	2.018AsnArg: 2.018 ± 0.024	2.337AsnSer: 2.337 ± 0.026	1.615AsnThr: 1.615 ± 0.02	2.086AsnVal: 2.086 ± 0.022	0.465AsnTrp: 0.465 ± 0.01	0.865AsnTyr: 0.865 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	5.805ProAla: 5.805 ± 0.051	0.728ProCys: 0.728 ± 0.013	3.448ProAsp: 3.448 ± 0.031	3.189ProGlu: 3.189 ± 0.028	2.045ProPhe: 2.045 ± 0.024	4.022ProGly: 4.022 ± 0.034	1.366ProHis: 1.366 ± 0.019	2.164ProIle: 2.164 ± 0.023	2.284ProLys: 2.284 ± 0.024	5.239ProLeu: 5.239 ± 0.038	1.121ProMet: 1.121 ± 0.019	1.812ProAsn: 1.812 ± 0.023	6.827ProPro: 6.827 ± 0.105	2.3ProGln: 2.3 ± 0.03	4.262ProArg: 4.262 ± 0.036	6.477ProSer: 6.477 ± 0.061	3.818ProThr: 3.818 ± 0.034	3.653ProVal: 3.653 ± 0.034	0.765ProTrp: 0.765 ± 0.014	1.677ProTyr: 1.677 ± 0.027	0.0ProXaa: 0.0 ± 0.0
Gln	3.552GlnAla: 3.552 ± 0.034	0.403GlnCys: 0.403 ± 0.01	1.98GlnAsp: 1.98 ± 0.024	2.002GlnGlu: 2.002 ± 0.024	1.067GlnPhe: 1.067 ± 0.017	2.557GlnGly: 2.557 ± 0.028	1.132GlnHis: 1.132 ± 0.023	1.461GlnIle: 1.461 ± 0.02	1.668GlnLys: 1.668 ± 0.024	3.486GlnLeu: 3.486 ± 0.034	0.868GlnMet: 0.868 ± 0.016	1.12GlnAsn: 1.12 ± 0.019	2.643GlnPro: 2.643 ± 0.033	3.366GlnGln: 3.366 ± 0.089	3.044GlnArg: 3.044 ± 0.028	2.788GlnSer: 2.788 ± 0.027	2.091GlnThr: 2.091 ± 0.025	2.199GlnVal: 2.199 ± 0.022	0.464GlnTrp: 0.464 ± 0.013	0.901GlnTyr: 0.901 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	5.791ArgAla: 5.791 ± 0.043	1.117ArgCys: 1.117 ± 0.019	4.094ArgAsp: 4.094 ± 0.033	4.032ArgGlu: 4.032 ± 0.039	2.354ArgPhe: 2.354 ± 0.025	4.532ArgGly: 4.532 ± 0.041	2.213ArgHis: 2.213 ± 0.029	2.864ArgIle: 2.864 ± 0.028	3.475ArgLys: 3.475 ± 0.029	7.147ArgLeu: 7.147 ± 0.051	1.413ArgMet: 1.413 ± 0.019	2.288ArgAsn: 2.288 ± 0.025	4.925ArgPro: 4.925 ± 0.046	3.21ArgGln: 3.21 ± 0.03	7.525ArgArg: 7.525 ± 0.068	5.604ArgSer: 5.604 ± 0.052	3.543ArgThr: 3.543 ± 0.028	3.819ArgVal: 3.819 ± 0.029	1.051ArgTrp: 1.051 ± 0.018	1.971ArgTyr: 1.971 ± 0.024	0.0ArgXaa: 0.0 ± 0.0
Ser	7.073SerAla: 7.073 ± 0.057	1.035SerCys: 1.035 ± 0.017	4.273SerAsp: 4.273 ± 0.041	3.52SerGlu: 3.52 ± 0.032	3.078SerPhe: 3.078 ± 0.028	5.541SerGly: 5.541 ± 0.046	1.98SerHis: 1.98 ± 0.023	3.465SerIle: 3.465 ± 0.032	3.255SerLys: 3.255 ± 0.032	7.807SerLeu: 7.807 ± 0.045	1.672SerMet: 1.672 ± 0.022	2.53SerAsn: 2.53 ± 0.027	5.949SerPro: 5.949 ± 0.063	2.995SerGln: 2.995 ± 0.031	6.173SerArg: 6.173 ± 0.045	10.826SerSer: 10.826 ± 0.106	4.92SerThr: 4.92 ± 0.044	4.673SerVal: 4.673 ± 0.038	1.065SerTrp: 1.065 ± 0.017	1.96SerTyr: 1.96 ± 0.023	0.0SerXaa: 0.0 ± 0.0
Thr	5.615ThrAla: 5.615 ± 0.043	0.807ThrCys: 0.807 ± 0.014	2.634ThrAsp: 2.634 ± 0.025	2.651ThrGlu: 2.651 ± 0.025	1.865ThrPhe: 1.865 ± 0.019	3.773ThrGly: 3.773 ± 0.034	1.139ThrHis: 1.139 ± 0.02	2.42ThrIle: 2.42 ± 0.025	2.348ThrLys: 2.348 ± 0.029	4.891ThrLeu: 4.891 ± 0.036	1.333ThrMet: 1.333 ± 0.017	1.719ThrAsn: 1.719 ± 0.021	3.79ThrPro: 3.79 ± 0.038	1.748ThrGln: 1.748 ± 0.021	3.482ThrArg: 3.482 ± 0.029	4.763ThrSer: 4.763 ± 0.041	4.583ThrThr: 4.583 ± 0.055	3.568ThrVal: 3.568 ± 0.035	0.748ThrTrp: 0.748 ± 0.013	1.483ThrTyr: 1.483 ± 0.021	0.0ThrXaa: 0.0 ± 0.0
Val	5.921ValAla: 5.921 ± 0.045	0.945ValCys: 0.945 ± 0.014	4.196ValAsp: 4.196 ± 0.032	3.956ValGlu: 3.956 ± 0.034	2.47ValPhe: 2.47 ± 0.028	4.383ValGly: 4.383 ± 0.035	1.315ValHis: 1.315 ± 0.017	2.796ValIle: 2.796 ± 0.028	2.703ValLys: 2.703 ± 0.025	5.702ValLeu: 5.702 ± 0.043	1.476ValMet: 1.476 ± 0.018	1.902ValAsn: 1.902 ± 0.023	3.618ValPro: 3.618 ± 0.032	2.222ValGln: 2.222 ± 0.022	4.27ValArg: 4.27 ± 0.036	4.668ValSer: 4.668 ± 0.036	3.571ValThr: 3.571 ± 0.034	5.075ValVal: 5.075 ± 0.047	0.842ValTrp: 0.842 ± 0.013	1.524ValTyr: 1.524 ± 0.02	0.0ValXaa: 0.0 ± 0.0
Trp	1.07TrpAla: 1.07 ± 0.016	0.191TrpCys: 0.191 ± 0.007	0.825TrpAsp: 0.825 ± 0.016	0.73TrpGlu: 0.73 ± 0.015	0.468TrpPhe: 0.468 ± 0.01	0.754TrpGly: 0.754 ± 0.014	0.369TrpHis: 0.369 ± 0.01	0.607TrpIle: 0.607 ± 0.014	0.645TrpLys: 0.645 ± 0.013	1.406TrpLeu: 1.406 ± 0.019	0.339TrpMet: 0.339 ± 0.009	0.536TrpAsn: 0.536 ± 0.013	0.698TrpPro: 0.698 ± 0.014	0.527TrpGln: 0.527 ± 0.012	1.092TrpArg: 1.092 ± 0.015	0.968TrpSer: 0.968 ± 0.016	0.824TrpThr: 0.824 ± 0.015	0.781TrpVal: 0.781 ± 0.014	0.242TrpTrp: 0.242 ± 0.008	0.391TrpTyr: 0.391 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.951TyrAla: 1.951 ± 0.024	0.397TyrCys: 0.397 ± 0.01	1.588TyrAsp: 1.588 ± 0.021	1.288TyrGlu: 1.288 ± 0.019	1.022TyrPhe: 1.022 ± 0.015	2.289TyrGly: 2.289 ± 0.033	0.688TyrHis: 0.688 ± 0.013	1.018TyrIle: 1.018 ± 0.017	0.98TyrLys: 0.98 ± 0.018	2.576TyrLeu: 2.576 ± 0.027	0.549TyrMet: 0.549 ± 0.012	0.939TyrAsn: 0.939 ± 0.016	1.335TyrPro: 1.335 ± 0.023	0.882TyrGln: 0.882 ± 0.015	1.761TyrArg: 1.761 ± 0.022	2.087TyrSer: 2.087 ± 0.023	1.217TyrThr: 1.217 ± 0.015	1.719TyrVal: 1.719 ± 0.02	0.376TyrTrp: 0.376 ± 0.01	0.798TyrTyr: 0.798 ± 0.013	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.048XaaXaa: 0.048 ± 0.026

Statistics based on 10104 proteins (4359552 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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