Amino acid dipepetide frequency for Murutucu virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.989AlaAla: 2.989 ± 1.944
1.743AlaCys: 1.743 ± 0.599
1.993AlaAsp: 1.993 ± 1.132
3.238AlaGlu: 3.238 ± 0.956
2.989AlaPhe: 2.989 ± 0.852
1.743AlaGly: 1.743 ± 1.128
0.498AlaHis: 0.498 ± 0.142
3.736AlaIle: 3.736 ± 0.627
6.227AlaLys: 6.227 ± 2.452
4.981AlaLeu: 4.981 ± 1.333
0.747AlaMet: 0.747 ± 0.201
4.234AlaAsn: 4.234 ± 2.116
1.245AlaPro: 1.245 ± 0.757
1.993AlaGln: 1.993 ± 1.082
1.993AlaArg: 1.993 ± 0.622
3.238AlaSer: 3.238 ± 1.017
2.242AlaThr: 2.242 ± 0.45
3.238AlaVal: 3.238 ± 0.858
0.498AlaTrp: 0.498 ± 0.142
1.993AlaTyr: 1.993 ± 0.363
0.0AlaXaa: 0.0 ± 0.0
Cys
1.743CysAla: 1.743 ± 0.685
0.249CysCys: 0.249 ± 0.153
0.498CysAsp: 0.498 ± 0.142
1.494CysGlu: 1.494 ± 0.972
2.242CysPhe: 2.242 ± 0.998
2.989CysGly: 2.989 ± 1.33
0.249CysHis: 0.249 ± 0.216
1.245CysIle: 1.245 ± 0.312
1.993CysLys: 1.993 ± 1.086
2.491CysLeu: 2.491 ± 0.927
0.498CysMet: 0.498 ± 0.142
1.993CysAsn: 1.993 ± 0.568
1.245CysPro: 1.245 ± 0.463
0.747CysGln: 0.747 ± 0.333
0.498CysArg: 0.498 ± 0.433
2.491CysSer: 2.491 ± 0.625
2.242CysThr: 2.242 ± 1.299
2.242CysVal: 2.242 ± 1.619
0.249CysTrp: 0.249 ± 0.153
0.747CysTyr: 0.747 ± 0.333
0.0CysXaa: 0.0 ± 0.0
Asp
1.743AspAla: 1.743 ± 0.768
1.494AspCys: 1.494 ± 0.426
3.487AspAsp: 3.487 ± 0.902
4.234AspGlu: 4.234 ± 0.649
3.736AspPhe: 3.736 ± 1.241
1.993AspGly: 1.993 ± 0.661
0.249AspHis: 0.249 ± 0.216
3.238AspIle: 3.238 ± 1.017
2.491AspLys: 2.491 ± 0.311
5.23AspLeu: 5.23 ± 1.322
1.993AspMet: 1.993 ± 0.656
2.242AspAsn: 2.242 ± 0.603
1.993AspPro: 1.993 ± 0.583
2.242AspGln: 2.242 ± 1.071
3.487AspArg: 3.487 ± 0.94
2.242AspSer: 2.242 ± 0.998
3.487AspThr: 3.487 ± 1.695
4.234AspVal: 4.234 ± 0.887
0.249AspTrp: 0.249 ± 0.153
1.743AspTyr: 1.743 ± 0.442
0.0AspXaa: 0.0 ± 0.0
Glu
2.74GluAla: 2.74 ± 0.475
0.996GluCys: 0.996 ± 0.284
2.989GluAsp: 2.989 ± 1.237
3.238GluGlu: 3.238 ± 0.896
5.479GluPhe: 5.479 ± 1.542
1.245GluGly: 1.245 ± 0.463
1.743GluHis: 1.743 ± 1.402
8.219GluIle: 8.219 ± 1.27
3.985GluLys: 3.985 ± 0.809
5.978GluLeu: 5.978 ± 1.065
3.487GluMet: 3.487 ± 1.518
3.238GluAsn: 3.238 ± 0.956
1.743GluPro: 1.743 ± 0.522
1.993GluGln: 1.993 ± 0.506
3.985GluArg: 3.985 ± 1.057
3.985GluSer: 3.985 ± 0.748
3.985GluThr: 3.985 ± 1.588
2.989GluVal: 2.989 ± 0.804
0.249GluTrp: 0.249 ± 0.153
1.993GluTyr: 1.993 ± 0.656
0.0GluXaa: 0.0 ± 0.0
Phe
2.242PheAla: 2.242 ± 0.577
2.491PheCys: 2.491 ± 1.223
2.989PheAsp: 2.989 ± 0.659
4.732PheGlu: 4.732 ± 0.597
2.491PhePhe: 2.491 ± 1.017
1.993PheGly: 1.993 ± 1.132
0.996PheHis: 0.996 ± 0.328
3.487PheIle: 3.487 ± 0.921
4.981PheLys: 4.981 ± 1.439
3.736PheLeu: 3.736 ± 2.879
0.996PheMet: 0.996 ± 0.328
1.743PheAsn: 1.743 ± 1.072
1.494PhePro: 1.494 ± 0.595
1.245PheGln: 1.245 ± 0.471
1.993PheArg: 1.993 ± 0.861
3.985PheSer: 3.985 ± 1.057
2.989PheThr: 2.989 ± 1.062
2.491PheVal: 2.491 ± 0.941
0.249PheTrp: 0.249 ± 0.153
2.74PheTyr: 2.74 ± 1.126
0.0PheXaa: 0.0 ± 0.0
Gly
1.245GlyAla: 1.245 ± 0.508
2.242GlyCys: 2.242 ± 1.299
3.238GlyAsp: 3.238 ± 0.618
3.985GlyGlu: 3.985 ± 1.039
0.747GlyPhe: 0.747 ± 0.635
0.996GlyGly: 0.996 ± 0.328
0.249GlyHis: 0.249 ± 0.216
4.483GlyIle: 4.483 ± 0.481
2.74GlyLys: 2.74 ± 0.877
2.989GlyLeu: 2.989 ± 1.382
1.245GlyMet: 1.245 ± 0.757
2.989GlyAsn: 2.989 ± 0.804
0.996GlyPro: 0.996 ± 0.284
0.996GlyGln: 0.996 ± 0.541
1.993GlyArg: 1.993 ± 0.861
2.491GlySer: 2.491 ± 1.651
2.74GlyThr: 2.74 ± 1.865
2.491GlyVal: 2.491 ± 1.265
0.996GlyTrp: 0.996 ± 0.284
2.242GlyTyr: 2.242 ± 0.577
0.0GlyXaa: 0.0 ± 0.0
His
0.498HisAla: 0.498 ± 0.433
0.498HisCys: 0.498 ± 0.142
0.498HisAsp: 0.498 ± 0.433
0.996HisGlu: 0.996 ± 0.639
1.494HisPhe: 1.494 ± 0.919
1.245HisGly: 1.245 ± 0.471
0.996HisHis: 0.996 ± 0.543
1.245HisIle: 1.245 ± 0.471
1.245HisLys: 1.245 ± 0.463
1.494HisLeu: 1.494 ± 0.75
0.498HisMet: 0.498 ± 0.142
2.491HisAsn: 2.491 ± 0.941
1.245HisPro: 1.245 ± 0.463
0.249HisGln: 0.249 ± 0.216
1.245HisArg: 1.245 ± 2.039
1.494HisSer: 1.494 ± 0.426
0.996HisThr: 0.996 ± 0.543
0.498HisVal: 0.498 ± 0.306
0.498HisTrp: 0.498 ± 0.306
1.245HisTyr: 1.245 ± 0.732
0.0HisXaa: 0.0 ± 0.0
Ile
3.985IleAla: 3.985 ± 0.37
1.245IleCys: 1.245 ± 0.757
3.736IleAsp: 3.736 ± 1.525
5.978IleGlu: 5.978 ± 0.891
3.736IlePhe: 3.736 ± 1.39
3.238IleGly: 3.238 ± 1.123
1.743IleHis: 1.743 ± 0.522
6.227IleIle: 6.227 ± 1.499
8.468IleLys: 8.468 ± 2.677
9.714IleLeu: 9.714 ± 1.147
2.74IleMet: 2.74 ± 0.703
5.23IleAsn: 5.23 ± 0.745
2.74IlePro: 2.74 ± 0.703
3.487IleGln: 3.487 ± 1.687
3.487IleArg: 3.487 ± 1.414
4.732IleSer: 4.732 ± 1.045
3.985IleThr: 3.985 ± 1.653
3.238IleVal: 3.238 ± 0.919
0.747IleTrp: 0.747 ± 0.201
2.242IleTyr: 2.242 ± 1.045
0.0IleXaa: 0.0 ± 0.0
Lys
2.989LysAla: 2.989 ± 0.752
2.74LysCys: 2.74 ± 1.417
5.23LysAsp: 5.23 ± 0.745
6.725LysGlu: 6.725 ± 1.395
2.74LysPhe: 2.74 ± 1.207
4.483LysGly: 4.483 ± 0.707
1.993LysHis: 1.993 ± 0.656
5.23LysIle: 5.23 ± 1.257
5.479LysLys: 5.479 ± 0.773
7.472LysLeu: 7.472 ± 0.932
3.238LysMet: 3.238 ± 0.536
4.234LysAsn: 4.234 ± 0.488
2.491LysPro: 2.491 ± 0.311
1.743LysGln: 1.743 ± 1.273
1.993LysArg: 1.993 ± 0.622
5.23LysSer: 5.23 ± 0.745
4.981LysThr: 4.981 ± 1.42
3.985LysVal: 3.985 ± 1.426
0.996LysTrp: 0.996 ± 0.541
2.74LysTyr: 2.74 ± 0.848
0.0LysXaa: 0.0 ± 0.0
Leu
6.227LeuAla: 6.227 ± 2.366
1.993LeuCys: 1.993 ± 1.086
5.479LeuAsp: 5.479 ± 2.176
6.227LeuGlu: 6.227 ± 1.063
3.487LeuPhe: 3.487 ± 1.124
2.989LeuGly: 2.989 ± 1.546
2.242LeuHis: 2.242 ± 1.045
7.472LeuIle: 7.472 ± 1.366
6.227LeuLys: 6.227 ± 1.141
10.212LeuLeu: 10.212 ± 2.345
2.74LeuMet: 2.74 ± 1.201
7.223LeuAsn: 7.223 ± 2.293
3.736LeuPro: 3.736 ± 1.574
3.487LeuGln: 3.487 ± 1.234
5.23LeuArg: 5.23 ± 3.344
8.468LeuSer: 8.468 ± 2.028
5.479LeuThr: 5.479 ± 1.893
3.487LeuVal: 3.487 ± 0.884
0.249LeuTrp: 0.249 ± 0.153
3.736LeuTyr: 3.736 ± 0.599
0.0LeuXaa: 0.0 ± 0.0
Met
1.245MetAla: 1.245 ± 0.526
0.996MetCys: 0.996 ± 0.543
0.996MetAsp: 0.996 ± 0.328
0.996MetGlu: 0.996 ± 0.613
1.245MetPhe: 1.245 ± 0.526
1.245MetGly: 1.245 ± 0.463
0.996MetHis: 0.996 ± 0.284
2.74MetIle: 2.74 ± 0.791
3.238MetLys: 3.238 ± 0.896
3.736MetLeu: 3.736 ± 0.942
1.494MetMet: 1.494 ± 0.618
1.743MetAsn: 1.743 ± 0.768
2.242MetPro: 2.242 ± 0.603
0.498MetGln: 0.498 ± 0.433
2.491MetArg: 2.491 ± 0.604
3.487MetSer: 3.487 ± 2.184
2.491MetThr: 2.491 ± 0.71
1.993MetVal: 1.993 ± 0.861
0.0MetTrp: 0.0 ± 0.0
0.747MetTyr: 0.747 ± 0.333
0.0MetXaa: 0.0 ± 0.0
Asn
2.989AsnAla: 2.989 ± 0.804
0.996AsnCys: 0.996 ± 0.543
4.234AsnAsp: 4.234 ± 1.535
3.985AsnGlu: 3.985 ± 0.541
2.491AsnPhe: 2.491 ± 0.941
1.743AsnGly: 1.743 ± 0.866
1.993AsnHis: 1.993 ± 0.975
4.732AsnIle: 4.732 ± 0.638
4.234AsnLys: 4.234 ± 0.854
5.729AsnLeu: 5.729 ± 1.15
2.989AsnMet: 2.989 ± 0.493
3.736AsnAsn: 3.736 ± 0.627
2.491AsnPro: 2.491 ± 0.311
2.242AsnGln: 2.242 ± 1.071
1.245AsnArg: 1.245 ± 0.463
2.74AsnSer: 2.74 ± 0.259
4.483AsnThr: 4.483 ± 0.937
2.491AsnVal: 2.491 ± 0.71
0.498AsnTrp: 0.498 ± 0.306
2.491AsnTyr: 2.491 ± 0.625
0.0AsnXaa: 0.0 ± 0.0
Pro
2.989ProAla: 2.989 ± 0.264
0.0ProCys: 0.0 ± 0.0
1.245ProAsp: 1.245 ± 0.508
2.74ProGlu: 2.74 ± 0.687
1.245ProPhe: 1.245 ± 0.463
2.242ProGly: 2.242 ± 0.469
0.249ProHis: 0.249 ± 0.216
3.487ProIle: 3.487 ± 0.736
3.487ProLys: 3.487 ± 0.438
2.242ProLeu: 2.242 ± 1.835
0.747ProMet: 0.747 ± 0.333
2.74ProAsn: 2.74 ± 0.877
0.498ProPro: 0.498 ± 0.306
0.498ProGln: 0.498 ± 0.142
0.498ProArg: 0.498 ± 0.306
2.989ProSer: 2.989 ± 0.804
1.743ProThr: 1.743 ± 0.654
2.74ProVal: 2.74 ± 0.475
0.747ProTrp: 0.747 ± 0.635
0.996ProTyr: 0.996 ± 0.284
0.0ProXaa: 0.0 ± 0.0
Gln
2.491GlnAla: 2.491 ± 0.975
0.996GlnCys: 0.996 ± 0.284
2.242GlnAsp: 2.242 ± 0.577
1.494GlnGlu: 1.494 ± 0.665
1.245GlnPhe: 1.245 ± 0.471
1.743GlnGly: 1.743 ± 0.468
0.249GlnHis: 0.249 ± 0.216
1.743GlnIle: 1.743 ± 1.034
2.491GlnLys: 2.491 ± 1.017
3.238GlnLeu: 3.238 ± 0.71
0.996GlnMet: 0.996 ± 0.613
0.747GlnAsn: 0.747 ± 0.612
0.747GlnPro: 0.747 ± 0.333
1.494GlnGln: 1.494 ± 0.521
2.491GlnArg: 2.491 ± 0.889
3.985GlnSer: 3.985 ± 1.568
2.74GlnThr: 2.74 ± 1.088
1.245GlnVal: 1.245 ± 0.312
0.498GlnTrp: 0.498 ± 0.142
1.245GlnTyr: 1.245 ± 0.508
0.0GlnXaa: 0.0 ± 0.0
Arg
1.743ArgAla: 1.743 ± 1.232
1.743ArgCys: 1.743 ± 0.442
2.989ArgAsp: 2.989 ± 1.154
1.743ArgGlu: 1.743 ± 1.072
1.993ArgPhe: 1.993 ± 0.583
1.743ArgGly: 1.743 ± 0.725
0.747ArgHis: 0.747 ± 0.459
4.981ArgIle: 4.981 ± 1.95
2.989ArgLys: 2.989 ± 0.362
3.985ArgLeu: 3.985 ± 3.142
2.242ArgMet: 2.242 ± 0.664
2.242ArgAsn: 2.242 ± 0.949
0.249ArgPro: 0.249 ± 0.716
1.993ArgGln: 1.993 ± 1.037
1.245ArgArg: 1.245 ± 0.471
3.487ArgSer: 3.487 ± 1.412
2.242ArgThr: 2.242 ± 0.949
1.993ArgVal: 1.993 ± 1.037
0.249ArgTrp: 0.249 ± 0.216
2.242ArgTyr: 2.242 ± 1.071
0.0ArgXaa: 0.0 ± 0.0
Ser
4.483SerAla: 4.483 ± 1.38
2.74SerCys: 2.74 ± 1.517
3.985SerAsp: 3.985 ± 1.118
3.985SerGlu: 3.985 ± 1.011
3.238SerPhe: 3.238 ± 0.746
2.242SerGly: 2.242 ± 1.357
2.242SerHis: 2.242 ± 0.664
5.479SerIle: 5.479 ± 1.375
4.981SerLys: 4.981 ± 0.621
9.465SerLeu: 9.465 ± 2.333
2.74SerMet: 2.74 ± 0.672
3.487SerAsn: 3.487 ± 1.198
2.491SerPro: 2.491 ± 0.941
2.491SerGln: 2.491 ± 0.606
4.234SerArg: 4.234 ± 0.809
4.483SerSer: 4.483 ± 5.28
3.487SerThr: 3.487 ± 0.875
5.729SerVal: 5.729 ± 0.32
0.747SerTrp: 0.747 ± 0.837
1.993SerTyr: 1.993 ± 0.794
0.0SerXaa: 0.0 ± 0.0
Thr
4.234ThrAla: 4.234 ± 0.425
1.245ThrCys: 1.245 ± 1.082
2.989ThrAsp: 2.989 ± 0.852
3.487ThrGlu: 3.487 ± 2.251
2.74ThrPhe: 2.74 ± 0.687
2.989ThrGly: 2.989 ± 1.629
1.245ThrHis: 1.245 ± 0.312
4.234ThrIle: 4.234 ± 1.328
3.238ThrLys: 3.238 ± 1.123
4.483ThrLeu: 4.483 ± 3.802
1.993ThrMet: 1.993 ± 0.563
2.989ThrAsn: 2.989 ± 0.752
2.74ThrPro: 2.74 ± 0.924
1.993ThrGln: 1.993 ± 0.506
1.993ThrArg: 1.993 ± 0.506
6.227ThrSer: 6.227 ± 0.318
2.74ThrThr: 2.74 ± 0.703
3.487ThrVal: 3.487 ± 0.736
1.245ThrTrp: 1.245 ± 1.253
3.487ThrTyr: 3.487 ± 0.884
0.0ThrXaa: 0.0 ± 0.0
Val
2.989ValAla: 2.989 ± 1.45
2.242ValCys: 2.242 ± 0.737
0.996ValAsp: 0.996 ± 0.543
2.74ValGlu: 2.74 ± 0.386
3.985ValPhe: 3.985 ± 0.741
3.238ValGly: 3.238 ± 0.854
0.498ValHis: 0.498 ± 0.306
3.487ValIle: 3.487 ± 1.267
4.483ValLys: 4.483 ± 1.278
4.234ValLeu: 4.234 ± 1.063
1.494ValMet: 1.494 ± 0.438
2.74ValAsn: 2.74 ± 0.867
2.491ValPro: 2.491 ± 0.311
2.242ValGln: 2.242 ± 0.577
1.245ValArg: 1.245 ± 1.642
5.729ValSer: 5.729 ± 0.879
3.238ValThr: 3.238 ± 0.629
1.743ValVal: 1.743 ± 0.468
0.0ValTrp: 0.0 ± 0.0
1.245ValTyr: 1.245 ± 0.732
0.0ValXaa: 0.0 ± 0.0
Trp
0.498TrpAla: 0.498 ± 0.659
0.0TrpCys: 0.0 ± 0.0
0.498TrpAsp: 0.498 ± 0.306
0.747TrpGlu: 0.747 ± 0.459
0.498TrpPhe: 0.498 ± 0.142
0.747TrpGly: 0.747 ± 0.612
0.0TrpHis: 0.0 ± 0.0
0.747TrpIle: 0.747 ± 0.333
0.249TrpLys: 0.249 ± 0.716
1.743TrpLeu: 1.743 ± 0.442
0.249TrpMet: 0.249 ± 0.716
0.498TrpAsn: 0.498 ± 0.306
0.0TrpPro: 0.0 ± 0.0
0.996TrpGln: 0.996 ± 0.85
0.0TrpArg: 0.0 ± 0.0
1.245TrpSer: 1.245 ± 0.471
0.0TrpThr: 0.0 ± 0.0
0.249TrpVal: 0.249 ± 0.153
0.0TrpTrp: 0.0 ± 0.0
0.498TrpTyr: 0.498 ± 0.306
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.494TyrAla: 1.494 ± 0.87
1.494TyrCys: 1.494 ± 1.299
1.494TyrAsp: 1.494 ± 0.426
1.743TyrGlu: 1.743 ± 0.522
2.242TyrPhe: 2.242 ± 0.577
1.245TyrGly: 1.245 ± 0.312
1.494TyrHis: 1.494 ± 0.665
4.483TyrIle: 4.483 ± 0.481
3.487TyrLys: 3.487 ± 0.289
3.238TyrLeu: 3.238 ± 0.345
1.245TyrMet: 1.245 ± 0.471
1.993TyrAsn: 1.993 ± 0.568
1.245TyrPro: 1.245 ± 0.694
1.494TyrGln: 1.494 ± 0.438
1.494TyrArg: 1.494 ± 0.521
1.993TyrSer: 1.993 ± 0.568
3.487TyrThr: 3.487 ± 0.902
0.498TyrVal: 0.498 ± 0.306
0.498TyrTrp: 0.498 ± 0.306
1.993TyrTyr: 1.993 ± 0.568
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (4016 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski