Amino acid dipepetide frequency for Niabella ginsenosidivorans

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.422AlaAla: 8.422 ± 0.099	0.76AlaCys: 0.76 ± 0.025	4.46AlaAsp: 4.46 ± 0.052	4.027AlaGlu: 4.027 ± 0.057	3.673AlaPhe: 3.673 ± 0.049	6.662AlaGly: 6.662 ± 0.063	1.411AlaHis: 1.411 ± 0.031	5.391AlaIle: 5.391 ± 0.061	4.368AlaLys: 4.368 ± 0.052	7.736AlaLeu: 7.736 ± 0.079	1.719AlaMet: 1.719 ± 0.035	3.374AlaAsn: 3.374 ± 0.052	3.023AlaPro: 3.023 ± 0.053	3.125AlaGln: 3.125 ± 0.053	3.22AlaArg: 3.22 ± 0.046	4.558AlaSer: 4.558 ± 0.06	4.492AlaThr: 4.492 ± 0.059	5.634AlaVal: 5.634 ± 0.063	0.904AlaTrp: 0.904 ± 0.028	3.087AlaTyr: 3.087 ± 0.041	0.0AlaXaa: 0.0 ± 0.0
Cys	0.585CysAla: 0.585 ± 0.019	0.164CysCys: 0.164 ± 0.009	0.353CysAsp: 0.353 ± 0.015	0.329CysGlu: 0.329 ± 0.015	0.539CysPhe: 0.539 ± 0.017	0.643CysGly: 0.643 ± 0.021	0.201CysHis: 0.201 ± 0.014	0.682CysIle: 0.682 ± 0.02	0.485CysLys: 0.485 ± 0.017	0.811CysLeu: 0.811 ± 0.024	0.227CysMet: 0.227 ± 0.013	0.444CysAsn: 0.444 ± 0.017	0.362CysPro: 0.362 ± 0.017	0.21CysGln: 0.21 ± 0.011	0.413CysArg: 0.413 ± 0.015	0.614CysSer: 0.614 ± 0.022	0.489CysThr: 0.489 ± 0.017	0.446CysVal: 0.446 ± 0.017	0.135CysTrp: 0.135 ± 0.009	0.368CysTyr: 0.368 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	4.432AspAla: 4.432 ± 0.047	0.388AspCys: 0.388 ± 0.015	2.274AspAsp: 2.274 ± 0.044	3.006AspGlu: 3.006 ± 0.048	2.786AspPhe: 2.786 ± 0.049	3.738AspGly: 3.738 ± 0.058	1.12AspHis: 1.12 ± 0.026	3.527AspIle: 3.527 ± 0.047	3.305AspLys: 3.305 ± 0.048	4.731AspLeu: 4.731 ± 0.057	1.011AspMet: 1.011 ± 0.024	2.503AspAsn: 2.503 ± 0.04	2.522AspPro: 2.522 ± 0.046	1.857AspGln: 1.857 ± 0.039	2.289AspArg: 2.289 ± 0.035	2.867AspSer: 2.867 ± 0.054	2.606AspThr: 2.606 ± 0.044	3.114AspVal: 3.114 ± 0.046	0.846AspTrp: 0.846 ± 0.026	2.544AspTyr: 2.544 ± 0.045	0.0AspXaa: 0.0 ± 0.0
Glu	4.718GluAla: 4.718 ± 0.066	0.359GluCys: 0.359 ± 0.014	2.525GluAsp: 2.525 ± 0.046	3.532GluGlu: 3.532 ± 0.063	1.977GluPhe: 1.977 ± 0.036	3.483GluGly: 3.483 ± 0.047	1.096GluHis: 1.096 ± 0.029	3.651GluIle: 3.651 ± 0.06	4.823GluLys: 4.823 ± 0.068	5.482GluLeu: 5.482 ± 0.074	1.384GluMet: 1.384 ± 0.032	2.995GluAsn: 2.995 ± 0.043	1.732GluPro: 1.732 ± 0.035	2.814GluGln: 2.814 ± 0.042	2.576GluArg: 2.576 ± 0.045	2.393GluSer: 2.393 ± 0.044	2.854GluThr: 2.854 ± 0.05	3.33GluVal: 3.33 ± 0.049	0.807GluTrp: 0.807 ± 0.024	2.045GluTyr: 2.045 ± 0.033	0.0GluXaa: 0.0 ± 0.0
Phe	3.161PheAla: 3.161 ± 0.045	0.504PheCys: 0.504 ± 0.015	2.721PheAsp: 2.721 ± 0.04	2.57PheGlu: 2.57 ± 0.046	2.514PhePhe: 2.514 ± 0.05	3.138PheGly: 3.138 ± 0.048	0.877PheHis: 0.877 ± 0.023	3.595PheIle: 3.595 ± 0.06	2.869PheLys: 2.869 ± 0.045	4.5PheLeu: 4.5 ± 0.068	1.106PheMet: 1.106 ± 0.025	2.705PheAsn: 2.705 ± 0.041	1.867PhePro: 1.867 ± 0.036	1.372PheGln: 1.372 ± 0.03	2.178PheArg: 2.178 ± 0.043	3.456PheSer: 3.456 ± 0.045	2.999PheThr: 2.999 ± 0.047	2.659PheVal: 2.659 ± 0.043	0.62PheTrp: 0.62 ± 0.023	2.234PheTyr: 2.234 ± 0.039	0.0PheXaa: 0.0 ± 0.0
Gly	5.396GlyAla: 5.396 ± 0.059	0.675GlyCys: 0.675 ± 0.022	3.296GlyAsp: 3.296 ± 0.051	3.104GlyGlu: 3.104 ± 0.05	3.655GlyPhe: 3.655 ± 0.052	5.068GlyGly: 5.068 ± 0.074	1.316GlyHis: 1.316 ± 0.031	5.605GlyIle: 5.605 ± 0.065	5.27GlyLys: 5.27 ± 0.062	6.242GlyLeu: 6.242 ± 0.074	1.861GlyMet: 1.861 ± 0.033	4.082GlyAsn: 4.082 ± 0.062	1.767GlyPro: 1.767 ± 0.036	2.394GlyGln: 2.394 ± 0.041	3.128GlyArg: 3.128 ± 0.049	4.524GlySer: 4.524 ± 0.064	4.643GlyThr: 4.643 ± 0.064	4.39GlyVal: 4.39 ± 0.06	1.235GlyTrp: 1.235 ± 0.029	3.477GlyTyr: 3.477 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	1.217HisAla: 1.217 ± 0.032	0.223HisCys: 0.223 ± 0.012	0.758HisAsp: 0.758 ± 0.025	0.85HisGlu: 0.85 ± 0.022	1.252HisPhe: 1.252 ± 0.032	1.063HisGly: 1.063 ± 0.025	0.549HisHis: 0.549 ± 0.021	1.401HisIle: 1.401 ± 0.029	1.054HisLys: 1.054 ± 0.027	1.965HisLeu: 1.965 ± 0.037	0.385HisMet: 0.385 ± 0.016	0.924HisAsn: 0.924 ± 0.025	1.17HisPro: 1.17 ± 0.031	0.794HisGln: 0.794 ± 0.022	0.911HisArg: 0.911 ± 0.025	1.105HisSer: 1.105 ± 0.027	1.129HisThr: 1.129 ± 0.027	0.884HisVal: 0.884 ± 0.023	0.311HisTrp: 0.311 ± 0.015	0.979HisTyr: 0.979 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	5.898IleAla: 5.898 ± 0.08	0.709IleCys: 0.709 ± 0.021	3.78IleAsp: 3.78 ± 0.056	3.791IleGlu: 3.791 ± 0.057	2.789IlePhe: 2.789 ± 0.049	4.713IleGly: 4.713 ± 0.062	1.294IleHis: 1.294 ± 0.03	4.758IleIle: 4.758 ± 0.068	4.51IleLys: 4.51 ± 0.061	5.766IleLeu: 5.766 ± 0.068	1.278IleMet: 1.278 ± 0.031	3.841IleAsn: 3.841 ± 0.05	3.191IlePro: 3.191 ± 0.046	2.257IleGln: 2.257 ± 0.036	3.565IleArg: 3.565 ± 0.048	4.496IleSer: 4.496 ± 0.055	4.609IleThr: 4.609 ± 0.058	3.982IleVal: 3.982 ± 0.054	0.753IleTrp: 0.753 ± 0.022	2.539IleTyr: 2.539 ± 0.045	0.0IleXaa: 0.0 ± 0.0
Lys	5.258LysAla: 5.258 ± 0.061	0.311LysCys: 0.311 ± 0.014	4.06LysAsp: 4.06 ± 0.056	5.278LysGlu: 5.278 ± 0.069	2.047LysPhe: 2.047 ± 0.037	4.753LysGly: 4.753 ± 0.056	1.062LysHis: 1.062 ± 0.024	4.786LysIle: 4.786 ± 0.063	6.054LysLys: 6.054 ± 0.07	5.11LysLeu: 5.11 ± 0.06	1.876LysMet: 1.876 ± 0.031	4.247LysAsn: 4.247 ± 0.047	2.54LysPro: 2.54 ± 0.043	2.823LysGln: 2.823 ± 0.044	2.964LysArg: 2.964 ± 0.049	3.235LysSer: 3.235 ± 0.047	4.149LysThr: 4.149 ± 0.045	3.777LysVal: 3.777 ± 0.054	0.91LysTrp: 0.91 ± 0.027	2.617LysTyr: 2.617 ± 0.041	0.0LysXaa: 0.0 ± 0.0
Leu	6.654LeuAla: 6.654 ± 0.081	0.883LeuCys: 0.883 ± 0.027	4.346LeuAsp: 4.346 ± 0.053	4.77LeuGlu: 4.77 ± 0.069	5.005LeuPhe: 5.005 ± 0.076	5.715LeuGly: 5.715 ± 0.062	1.821LeuHis: 1.821 ± 0.037	5.965LeuIle: 5.965 ± 0.08	7.12LeuLys: 7.12 ± 0.063	10.381LeuLeu: 10.381 ± 0.117	2.174LeuMet: 2.174 ± 0.043	5.085LeuAsn: 5.085 ± 0.069	4.458LeuPro: 4.458 ± 0.054	4.302LeuGln: 4.302 ± 0.066	3.877LeuArg: 3.877 ± 0.049	6.375LeuSer: 6.375 ± 0.07	5.145LeuThr: 5.145 ± 0.055	5.25LeuVal: 5.25 ± 0.06	1.115LeuTrp: 1.115 ± 0.023	3.654LeuTyr: 3.654 ± 0.054	0.0LeuXaa: 0.0 ± 0.0
Met	1.905MetAla: 1.905 ± 0.037	0.12MetCys: 0.12 ± 0.008	1.22MetAsp: 1.22 ± 0.027	1.356MetGlu: 1.356 ± 0.03	0.69MetPhe: 0.69 ± 0.022	1.511MetGly: 1.511 ± 0.031	0.471MetHis: 0.471 ± 0.021	1.545MetIle: 1.545 ± 0.033	1.893MetLys: 1.893 ± 0.037	2.038MetLeu: 2.038 ± 0.037	0.556MetMet: 0.556 ± 0.02	1.34MetAsn: 1.34 ± 0.025	1.119MetPro: 1.119 ± 0.026	1.146MetGln: 1.146 ± 0.025	1.049MetArg: 1.049 ± 0.025	1.251MetSer: 1.251 ± 0.026	1.103MetThr: 1.103 ± 0.028	1.302MetVal: 1.302 ± 0.028	0.21MetTrp: 0.21 ± 0.011	0.714MetTyr: 0.714 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	4.296AsnAla: 4.296 ± 0.05	0.409AsnCys: 0.409 ± 0.018	2.73AsnAsp: 2.73 ± 0.041	2.883AsnGlu: 2.883 ± 0.039	2.3AsnPhe: 2.3 ± 0.042	4.396AsnGly: 4.396 ± 0.064	0.926AsnHis: 0.926 ± 0.028	3.939AsnIle: 3.939 ± 0.056	3.516AsnLys: 3.516 ± 0.057	4.169AsnLeu: 4.169 ± 0.055	1.124AsnMet: 1.124 ± 0.029	3.223AsnAsn: 3.223 ± 0.051	2.601AsnPro: 2.601 ± 0.037	1.764AsnGln: 1.764 ± 0.043	2.765AsnArg: 2.765 ± 0.048	3.036AsnSer: 3.036 ± 0.05	3.255AsnThr: 3.255 ± 0.05	2.938AsnVal: 2.938 ± 0.045	0.83AsnTrp: 0.83 ± 0.024	2.507AsnTyr: 2.507 ± 0.043	0.0AsnXaa: 0.0 ± 0.0
Pro	3.936ProAla: 3.936 ± 0.055	0.24ProCys: 0.24 ± 0.011	2.991ProAsp: 2.991 ± 0.039	3.085ProGlu: 3.085 ± 0.047	2.108ProPhe: 2.108 ± 0.035	3.659ProGly: 3.659 ± 0.051	0.718ProHis: 0.718 ± 0.021	1.804ProIle: 1.804 ± 0.034	1.933ProLys: 1.933 ± 0.034	3.662ProLeu: 3.662 ± 0.045	0.76ProMet: 0.76 ± 0.022	1.708ProAsn: 1.708 ± 0.037	1.389ProPro: 1.389 ± 0.031	1.618ProGln: 1.618 ± 0.036	1.449ProArg: 1.449 ± 0.031	2.308ProSer: 2.308 ± 0.036	1.7ProThr: 1.7 ± 0.032	4.209ProVal: 4.209 ± 0.056	0.523ProTrp: 0.523 ± 0.019	1.766ProTyr: 1.766 ± 0.036	0.0ProXaa: 0.0 ± 0.0
Gln	2.717GlnAla: 2.717 ± 0.046	0.25GlnCys: 0.25 ± 0.013	1.579GlnAsp: 1.579 ± 0.031	2.197GlnGlu: 2.197 ± 0.036	1.746GlnPhe: 1.746 ± 0.035	2.1GlnGly: 2.1 ± 0.038	0.888GlnHis: 0.888 ± 0.025	2.189GlnIle: 2.189 ± 0.039	2.951GlnLys: 2.951 ± 0.048	4.556GlnLeu: 4.556 ± 0.064	0.998GlnMet: 0.998 ± 0.025	1.949GlnAsn: 1.949 ± 0.037	1.825GlnPro: 1.825 ± 0.039	2.703GlnGln: 2.703 ± 0.056	1.713GlnArg: 1.713 ± 0.036	2.178GlnSer: 2.178 ± 0.035	2.184GlnThr: 2.184 ± 0.035	2.318GlnVal: 2.318 ± 0.04	0.644GlnTrp: 0.644 ± 0.021	1.83GlnTyr: 1.83 ± 0.04	0.0GlnXaa: 0.0 ± 0.0
Arg	2.847ArgAla: 2.847 ± 0.046	0.311ArgCys: 0.311 ± 0.016	1.96ArgAsp: 1.96 ± 0.036	2.497ArgGlu: 2.497 ± 0.043	2.545ArgPhe: 2.545 ± 0.039	2.369ArgGly: 2.369 ± 0.039	0.878ArgHis: 0.878 ± 0.025	3.379ArgIle: 3.379 ± 0.046	3.312ArgLys: 3.312 ± 0.048	4.534ArgLeu: 4.534 ± 0.056	1.159ArgMet: 1.159 ± 0.029	2.549ArgAsn: 2.549 ± 0.039	1.69ArgPro: 1.69 ± 0.038	1.985ArgGln: 1.985 ± 0.04	1.907ArgArg: 1.907 ± 0.036	2.73ArgSer: 2.73 ± 0.043	2.295ArgThr: 2.295 ± 0.046	2.552ArgVal: 2.552 ± 0.036	0.689ArgTrp: 0.689 ± 0.02	2.282ArgTyr: 2.282 ± 0.04	0.0ArgXaa: 0.0 ± 0.0
Ser	4.64SerAla: 4.64 ± 0.062	0.645SerCys: 0.645 ± 0.018	2.994SerAsp: 2.994 ± 0.045	2.636SerGlu: 2.636 ± 0.042	3.434SerPhe: 3.434 ± 0.045	5.286SerGly: 5.286 ± 0.065	0.93SerHis: 0.93 ± 0.024	4.109SerIle: 4.109 ± 0.053	3.428SerLys: 3.428 ± 0.049	5.703SerLeu: 5.703 ± 0.061	1.278SerMet: 1.278 ± 0.029	2.926SerAsn: 2.926 ± 0.055	2.207SerPro: 2.207 ± 0.034	1.74SerGln: 1.74 ± 0.037	2.8SerArg: 2.8 ± 0.044	3.833SerSer: 3.833 ± 0.06	3.07SerThr: 3.07 ± 0.053	4.169SerVal: 4.169 ± 0.052	0.92SerTrp: 0.92 ± 0.027	2.722SerTyr: 2.722 ± 0.057	0.0SerXaa: 0.0 ± 0.0
Thr	5.199ThrAla: 5.199 ± 0.068	0.39ThrCys: 0.39 ± 0.017	3.401ThrAsp: 3.401 ± 0.046	2.91ThrGlu: 2.91 ± 0.047	2.499ThrPhe: 2.499 ± 0.041	5.477ThrGly: 5.477 ± 0.06	0.998ThrHis: 0.998 ± 0.024	4.22ThrIle: 4.22 ± 0.05	2.919ThrLys: 2.919 ± 0.047	5.137ThrLeu: 5.137 ± 0.061	1.008ThrMet: 1.008 ± 0.025	2.7ThrAsn: 2.7 ± 0.054	2.821ThrPro: 2.821 ± 0.046	1.851ThrGln: 1.851 ± 0.035	2.316ThrArg: 2.316 ± 0.041	3.101ThrSer: 3.101 ± 0.047	3.468ThrThr: 3.468 ± 0.059	4.103ThrVal: 4.103 ± 0.05	0.722ThrTrp: 0.722 ± 0.026	2.193ThrTyr: 2.193 ± 0.04	0.0ThrXaa: 0.0 ± 0.0
Val	4.842ValAla: 4.842 ± 0.06	0.602ValCys: 0.602 ± 0.02	2.926ValAsp: 2.926 ± 0.048	2.851ValGlu: 2.851 ± 0.054	3.202ValPhe: 3.202 ± 0.046	3.359ValGly: 3.359 ± 0.048	1.18ValHis: 1.18 ± 0.029	4.588ValIle: 4.588 ± 0.058	4.214ValLys: 4.214 ± 0.056	6.27ValLeu: 6.27 ± 0.066	1.351ValMet: 1.351 ± 0.025	3.478ValAsn: 3.478 ± 0.048	2.873ValPro: 2.873 ± 0.042	2.383ValGln: 2.383 ± 0.037	2.523ValArg: 2.523 ± 0.036	4.006ValSer: 4.006 ± 0.054	3.909ValThr: 3.909 ± 0.054	4.006ValVal: 4.006 ± 0.063	0.736ValTrp: 0.736 ± 0.024	2.592ValTyr: 2.592 ± 0.044	0.0ValXaa: 0.0 ± 0.0
Trp	0.915TrpAla: 0.915 ± 0.026	0.152TrpCys: 0.152 ± 0.011	0.706TrpAsp: 0.706 ± 0.021	0.789TrpGlu: 0.789 ± 0.021	0.589TrpPhe: 0.589 ± 0.019	0.996TrpGly: 0.996 ± 0.026	0.302TrpHis: 0.302 ± 0.013	0.824TrpIle: 0.824 ± 0.022	1.035TrpLys: 1.035 ± 0.024	1.363TrpLeu: 1.363 ± 0.025	0.443TrpMet: 0.443 ± 0.017	0.899TrpAsn: 0.899 ± 0.027	0.427TrpPro: 0.427 ± 0.016	0.651TrpGln: 0.651 ± 0.023	0.612TrpArg: 0.612 ± 0.022	0.754TrpSer: 0.754 ± 0.023	0.694TrpThr: 0.694 ± 0.025	0.824TrpVal: 0.824 ± 0.023	0.25TrpTrp: 0.25 ± 0.014	0.589TrpTyr: 0.589 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.009TyrAla: 3.009 ± 0.047	0.405TyrCys: 0.405 ± 0.017	2.387TyrAsp: 2.387 ± 0.045	2.113TyrGlu: 2.113 ± 0.045	2.296TyrPhe: 2.296 ± 0.041	2.998TyrGly: 2.998 ± 0.052	0.89TyrHis: 0.89 ± 0.023	2.562TyrIle: 2.562 ± 0.038	2.797TyrLys: 2.797 ± 0.051	3.937TyrLeu: 3.937 ± 0.048	0.84TyrMet: 0.84 ± 0.027	2.635TyrAsn: 2.635 ± 0.053	1.981TyrPro: 1.981 ± 0.044	1.724TyrGln: 1.724 ± 0.038	2.215TyrArg: 2.215 ± 0.038	2.649TyrSer: 2.649 ± 0.043	2.639TyrThr: 2.639 ± 0.05	2.006TyrVal: 2.006 ± 0.032	0.655TyrTrp: 0.655 ± 0.022	2.19TyrTyr: 2.19 ± 0.041	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4613 proteins (1588723 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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