Amino acid dipepetide frequency for Thanatephorus cucumeris (strain AG1-IA) (Rice sheath blight fungus) (Rhizoctonia solani)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.491AlaAla: 7.491 ± 0.052	1.195AlaCys: 1.195 ± 0.018	3.598AlaAsp: 3.598 ± 0.031	4.347AlaGlu: 4.347 ± 0.037	2.829AlaPhe: 2.829 ± 0.028	5.623AlaGly: 5.623 ± 0.042	2.109AlaHis: 2.109 ± 0.022	4.068AlaIle: 4.068 ± 0.034	3.602AlaLys: 3.602 ± 0.035	8.023AlaLeu: 8.023 ± 0.056	1.784AlaMet: 1.784 ± 0.02	2.828AlaAsn: 2.828 ± 0.028	5.489AlaPro: 5.489 ± 0.058	3.373AlaGln: 3.373 ± 0.036	5.54AlaArg: 5.54 ± 0.043	7.344AlaSer: 7.344 ± 0.049	5.148AlaThr: 5.148 ± 0.036	4.901AlaVal: 4.901 ± 0.04	1.14AlaTrp: 1.14 ± 0.019	2.224AlaTyr: 2.224 ± 0.024	0.0AlaXaa: 0.0 ± 0.0
Cys	1.195CysAla: 1.195 ± 0.021	0.341CysCys: 0.341 ± 0.01	0.715CysAsp: 0.715 ± 0.014	0.671CysGlu: 0.671 ± 0.013	0.55CysPhe: 0.55 ± 0.012	1.112CysGly: 1.112 ± 0.02	0.405CysHis: 0.405 ± 0.01	0.848CysIle: 0.848 ± 0.016	0.555CysLys: 0.555 ± 0.012	1.433CysLeu: 1.433 ± 0.02	0.328CysMet: 0.328 ± 0.008	0.456CysAsn: 0.456 ± 0.011	0.896CysPro: 0.896 ± 0.017	0.52CysGln: 0.52 ± 0.012	1.041CysArg: 1.041 ± 0.016	1.272CysSer: 1.272 ± 0.02	0.948CysThr: 0.948 ± 0.016	1.023CysVal: 1.023 ± 0.018	0.259CysTrp: 0.259 ± 0.008	0.408CysTyr: 0.408 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	4.147AspAla: 4.147 ± 0.037	0.64AspCys: 0.64 ± 0.013	3.331AspAsp: 3.331 ± 0.041	3.736AspGlu: 3.736 ± 0.037	1.731AspPhe: 1.731 ± 0.022	3.649AspGly: 3.649 ± 0.035	1.194AspHis: 1.194 ± 0.018	2.765AspIle: 2.765 ± 0.024	2.028AspLys: 2.028 ± 0.022	4.501AspLeu: 4.501 ± 0.036	1.124AspMet: 1.124 ± 0.018	1.595AspAsn: 1.595 ± 0.022	3.299AspPro: 3.299 ± 0.032	1.729AspGln: 1.729 ± 0.019	3.028AspArg: 3.028 ± 0.028	4.13AspSer: 4.13 ± 0.033	2.805AspThr: 2.805 ± 0.025	3.404AspVal: 3.404 ± 0.034	0.77AspTrp: 0.77 ± 0.013	1.386AspTyr: 1.386 ± 0.02	0.0AspXaa: 0.0 ± 0.0
Glu	4.409GluAla: 4.409 ± 0.041	0.734GluCys: 0.734 ± 0.016	3.354GluAsp: 3.354 ± 0.042	4.309GluGlu: 4.309 ± 0.06	1.752GluPhe: 1.752 ± 0.02	3.464GluGly: 3.464 ± 0.033	1.395GluHis: 1.395 ± 0.02	2.701GluIle: 2.701 ± 0.027	2.75GluLys: 2.75 ± 0.032	5.055GluLeu: 5.055 ± 0.041	1.215GluMet: 1.215 ± 0.018	1.825GluAsn: 1.825 ± 0.022	2.992GluPro: 2.992 ± 0.034	2.132GluGln: 2.132 ± 0.023	3.94GluArg: 3.94 ± 0.038	4.148GluSer: 4.148 ± 0.037	2.978GluThr: 2.978 ± 0.029	3.272GluVal: 3.272 ± 0.034	0.904GluTrp: 0.904 ± 0.019	1.546GluTyr: 1.546 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	2.828PheAla: 2.828 ± 0.028	0.544PheCys: 0.544 ± 0.012	1.957PheAsp: 1.957 ± 0.022	1.84PheGlu: 1.84 ± 0.02	1.294PhePhe: 1.294 ± 0.018	2.85PheGly: 2.85 ± 0.034	0.824PheHis: 0.824 ± 0.014	1.707PheIle: 1.707 ± 0.023	1.372PheLys: 1.372 ± 0.018	3.01PheLeu: 3.01 ± 0.03	0.698PheMet: 0.698 ± 0.012	1.278PheAsn: 1.278 ± 0.017	1.948PhePro: 1.948 ± 0.022	1.169PheGln: 1.169 ± 0.018	2.021PheArg: 2.021 ± 0.023	3.006PheSer: 3.006 ± 0.031	1.987PheThr: 1.987 ± 0.022	2.389PheVal: 2.389 ± 0.029	0.541PheTrp: 0.541 ± 0.011	0.908PheTyr: 0.908 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	5.493GlyAla: 5.493 ± 0.048	1.109GlyCys: 1.109 ± 0.02	3.249GlyAsp: 3.249 ± 0.026	3.457GlyGlu: 3.457 ± 0.032	2.43GlyPhe: 2.43 ± 0.026	5.69GlyGly: 5.69 ± 0.06	1.828GlyHis: 1.828 ± 0.023	3.432GlyIle: 3.432 ± 0.03	3.199GlyLys: 3.199 ± 0.034	6.026GlyLeu: 6.026 ± 0.039	1.64GlyMet: 1.64 ± 0.025	2.359GlyAsn: 2.359 ± 0.024	3.739GlyPro: 3.739 ± 0.034	2.484GlyGln: 2.484 ± 0.028	4.541GlyArg: 4.541 ± 0.034	6.272GlySer: 6.272 ± 0.052	4.398GlyThr: 4.398 ± 0.036	4.58GlyVal: 4.58 ± 0.042	1.195GlyTrp: 1.195 ± 0.017	2.044GlyTyr: 2.044 ± 0.026	0.0GlyXaa: 0.0 ± 0.0
His	2.042HisAla: 2.042 ± 0.024	0.386HisCys: 0.386 ± 0.011	1.232HisAsp: 1.232 ± 0.019	1.298HisGlu: 1.298 ± 0.019	0.912HisPhe: 0.912 ± 0.015	1.714HisGly: 1.714 ± 0.021	0.906HisHis: 0.906 ± 0.019	1.467HisIle: 1.467 ± 0.02	0.92HisLys: 0.92 ± 0.014	2.376HisLeu: 2.376 ± 0.024	0.54HisMet: 0.54 ± 0.013	0.835HisAsn: 0.835 ± 0.016	2.095HisPro: 2.095 ± 0.03	0.958HisGln: 0.958 ± 0.015	1.732HisArg: 1.732 ± 0.022	2.384HisSer: 2.384 ± 0.027	1.67HisThr: 1.67 ± 0.022	1.687HisVal: 1.687 ± 0.018	0.35HisTrp: 0.35 ± 0.009	0.677HisTyr: 0.677 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.14IleAla: 4.14 ± 0.033	0.833IleCys: 0.833 ± 0.014	2.737IleAsp: 2.737 ± 0.027	2.745IleGlu: 2.745 ± 0.028	1.713IlePhe: 1.713 ± 0.02	3.316IleGly: 3.316 ± 0.031	1.382IleHis: 1.382 ± 0.02	2.532IleIle: 2.532 ± 0.028	2.109IleLys: 2.109 ± 0.027	4.353IleLeu: 4.353 ± 0.036	1.02IleMet: 1.02 ± 0.019	1.794IleAsn: 1.794 ± 0.022	3.394IlePro: 3.394 ± 0.028	1.939IleGln: 1.939 ± 0.024	3.182IleArg: 3.182 ± 0.035	4.173IleSer: 4.173 ± 0.031	2.915IleThr: 2.915 ± 0.025	3.291IleVal: 3.291 ± 0.025	0.744IleTrp: 0.744 ± 0.017	1.436IleTyr: 1.436 ± 0.02	0.0IleXaa: 0.0 ± 0.0
Lys	3.629LysAla: 3.629 ± 0.042	0.598LysCys: 0.598 ± 0.014	2.303LysAsp: 2.303 ± 0.023	2.695LysGlu: 2.695 ± 0.033	1.31LysPhe: 1.31 ± 0.019	2.668LysGly: 2.668 ± 0.026	1.103LysHis: 1.103 ± 0.017	2.015LysIle: 2.015 ± 0.026	2.455LysLys: 2.455 ± 0.035	3.882LysLeu: 3.882 ± 0.029	0.864LysMet: 0.864 ± 0.015	1.491LysAsn: 1.491 ± 0.018	2.7LysPro: 2.7 ± 0.03	1.569LysGln: 1.569 ± 0.022	3.242LysArg: 3.242 ± 0.031	3.485LysSer: 3.485 ± 0.035	2.404LysThr: 2.404 ± 0.025	2.618LysVal: 2.618 ± 0.023	0.623LysTrp: 0.623 ± 0.012	1.227LysTyr: 1.227 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	7.923LeuAla: 7.923 ± 0.048	1.428LeuCys: 1.428 ± 0.019	4.808LeuAsp: 4.808 ± 0.034	4.991LeuGlu: 4.991 ± 0.046	3.245LeuPhe: 3.245 ± 0.033	6.389LeuGly: 6.389 ± 0.046	2.299LeuHis: 2.299 ± 0.027	4.067LeuIle: 4.067 ± 0.034	3.829LeuLys: 3.829 ± 0.034	8.006LeuLeu: 8.006 ± 0.06	1.703LeuMet: 1.703 ± 0.021	3.094LeuAsn: 3.094 ± 0.024	6.023LeuPro: 6.023 ± 0.044	3.207LeuGln: 3.207 ± 0.034	5.847LeuArg: 5.847 ± 0.042	7.821LeuSer: 7.821 ± 0.045	5.269LeuThr: 5.269 ± 0.043	5.962LeuVal: 5.962 ± 0.044	1.168LeuTrp: 1.168 ± 0.019	2.287LeuTyr: 2.287 ± 0.025	0.0LeuXaa: 0.0 ± 0.0
Met	1.835MetAla: 1.835 ± 0.023	0.333MetCys: 0.333 ± 0.01	1.138MetAsp: 1.138 ± 0.018	1.082MetGlu: 1.082 ± 0.015	0.717MetPhe: 0.717 ± 0.013	1.461MetGly: 1.461 ± 0.024	0.56MetHis: 0.56 ± 0.011	1.04MetIle: 1.04 ± 0.014	0.862MetLys: 0.862 ± 0.016	1.833MetLeu: 1.833 ± 0.021	0.523MetMet: 0.523 ± 0.012	0.831MetAsn: 0.831 ± 0.015	1.266MetPro: 1.266 ± 0.016	0.738MetGln: 0.738 ± 0.016	1.467MetArg: 1.467 ± 0.019	2.026MetSer: 2.026 ± 0.023	1.295MetThr: 1.295 ± 0.019	1.283MetVal: 1.283 ± 0.017	0.302MetTrp: 0.302 ± 0.009	0.554MetTyr: 0.554 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	2.944AsnAla: 2.944 ± 0.03	0.458AsnCys: 0.458 ± 0.01	1.7AsnAsp: 1.7 ± 0.021	1.84AsnGlu: 1.84 ± 0.022	1.139AsnPhe: 1.139 ± 0.016	2.593AsnGly: 2.593 ± 0.03	0.874AsnHis: 0.874 ± 0.012	1.896AsnIle: 1.896 ± 0.022	1.494AsnLys: 1.494 ± 0.019	3.152AsnLeu: 3.152 ± 0.026	0.808AsnMet: 0.808 ± 0.016	1.426AsnAsn: 1.426 ± 0.022	2.499AsnPro: 2.499 ± 0.028	1.337AsnGln: 1.337 ± 0.018	2.041AsnArg: 2.041 ± 0.022	2.977AsnSer: 2.977 ± 0.026	2.225AsnThr: 2.225 ± 0.029	2.286AsnVal: 2.286 ± 0.023	0.514AsnTrp: 0.514 ± 0.012	0.936AsnTyr: 0.936 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	5.483ProAla: 5.483 ± 0.044	0.752ProCys: 0.752 ± 0.017	3.242ProAsp: 3.242 ± 0.026	3.692ProGlu: 3.692 ± 0.034	2.103ProPhe: 2.103 ± 0.023	4.402ProGly: 4.402 ± 0.041	1.73ProHis: 1.73 ± 0.023	3.172ProIle: 3.172 ± 0.03	2.701ProLys: 2.701 ± 0.03	5.333ProLeu: 5.333 ± 0.037	1.186ProMet: 1.186 ± 0.016	2.568ProAsn: 2.568 ± 0.026	6.211ProPro: 6.211 ± 0.089	2.403ProGln: 2.403 ± 0.034	4.353ProArg: 4.353 ± 0.037	7.032ProSer: 7.032 ± 0.064	5.002ProThr: 5.002 ± 0.046	4.082ProVal: 4.082 ± 0.039	0.756ProTrp: 0.756 ± 0.014	1.601ProTyr: 1.601 ± 0.022	0.0ProXaa: 0.0 ± 0.0
Gln	3.204GlnAla: 3.204 ± 0.032	0.534GlnCys: 0.534 ± 0.013	1.723GlnAsp: 1.723 ± 0.022	1.891GlnGlu: 1.891 ± 0.02	1.161GlnPhe: 1.161 ± 0.017	2.297GlnGly: 2.297 ± 0.024	1.035GlnHis: 1.035 ± 0.019	1.806GlnIle: 1.806 ± 0.022	1.498GlnLys: 1.498 ± 0.021	3.489GlnLeu: 3.489 ± 0.03	0.808GlnMet: 0.808 ± 0.017	1.339GlnAsn: 1.339 ± 0.021	2.636GlnPro: 2.636 ± 0.035	1.859GlnGln: 1.859 ± 0.045	2.5GlnArg: 2.5 ± 0.024	3.172GlnSer: 3.172 ± 0.034	2.346GlnThr: 2.346 ± 0.024	2.375GlnVal: 2.375 ± 0.024	0.509GlnTrp: 0.509 ± 0.012	1.045GlnTyr: 1.045 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	5.648ArgAla: 5.648 ± 0.039	1.091ArgCys: 1.091 ± 0.019	3.213ArgAsp: 3.213 ± 0.032	3.66ArgGlu: 3.66 ± 0.039	2.23ArgPhe: 2.23 ± 0.024	4.143ArgGly: 4.143 ± 0.035	1.722ArgHis: 1.722 ± 0.02	3.374ArgIle: 3.374 ± 0.03	3.059ArgLys: 3.059 ± 0.029	5.974ArgLeu: 5.974 ± 0.043	1.551ArgMet: 1.551 ± 0.019	2.189ArgAsn: 2.189 ± 0.022	4.316ArgPro: 4.316 ± 0.04	2.41ArgGln: 2.41 ± 0.025	5.494ArgArg: 5.494 ± 0.047	5.841ArgSer: 5.841 ± 0.047	4.047ArgThr: 4.047 ± 0.031	4.16ArgVal: 4.16 ± 0.034	1.035ArgTrp: 1.035 ± 0.017	1.836ArgTyr: 1.836 ± 0.021	0.0ArgXaa: 0.0 ± 0.0
Ser	7.039SerAla: 7.039 ± 0.045	1.24SerCys: 1.24 ± 0.02	4.236SerAsp: 4.236 ± 0.035	4.153SerGlu: 4.153 ± 0.04	3.031SerPhe: 3.031 ± 0.028	6.198SerGly: 6.198 ± 0.044	2.364SerHis: 2.364 ± 0.027	4.335SerIle: 4.335 ± 0.033	3.596SerLys: 3.596 ± 0.031	7.739SerLeu: 7.739 ± 0.044	1.753SerMet: 1.753 ± 0.021	3.232SerAsn: 3.232 ± 0.032	6.57SerPro: 6.57 ± 0.075	3.298SerGln: 3.298 ± 0.032	6.123SerArg: 6.123 ± 0.042	9.431SerSer: 9.431 ± 0.076	6.384SerThr: 6.384 ± 0.057	5.31SerVal: 5.31 ± 0.036	1.152SerTrp: 1.152 ± 0.017	2.202SerTyr: 2.202 ± 0.024	0.0SerXaa: 0.0 ± 0.0
Thr	4.751ThrAla: 4.751 ± 0.041	0.935ThrCys: 0.935 ± 0.016	2.668ThrAsp: 2.668 ± 0.027	2.828ThrGlu: 2.828 ± 0.026	2.139ThrPhe: 2.139 ± 0.023	4.355ThrGly: 4.355 ± 0.039	1.723ThrHis: 1.723 ± 0.022	3.266ThrIle: 3.266 ± 0.03	2.487ThrLys: 2.487 ± 0.03	5.602ThrLeu: 5.602 ± 0.039	1.329ThrMet: 1.329 ± 0.017	2.286ThrAsn: 2.286 ± 0.028	5.156ThrPro: 5.156 ± 0.045	2.225ThrGln: 2.225 ± 0.025	4.124ThrArg: 4.124 ± 0.028	5.96ThrSer: 5.96 ± 0.049	4.496ThrThr: 4.496 ± 0.044	3.627ThrVal: 3.627 ± 0.029	0.873ThrTrp: 0.873 ± 0.015	1.641ThrTyr: 1.641 ± 0.023	0.0ThrXaa: 0.0 ± 0.0
Val	5.122ValAla: 5.122 ± 0.037	1.129ValCys: 1.129 ± 0.016	3.387ValAsp: 3.387 ± 0.03	3.511ValGlu: 3.511 ± 0.029	2.31ValPhe: 2.31 ± 0.025	4.38ValGly: 4.38 ± 0.038	1.605ValHis: 1.605 ± 0.02	3.074ValIle: 3.074 ± 0.029	2.656ValLys: 2.656 ± 0.027	5.847ValLeu: 5.847 ± 0.041	1.277ValMet: 1.277 ± 0.017	2.112ValAsn: 2.112 ± 0.023	4.253ValPro: 4.253 ± 0.041	2.416ValGln: 2.416 ± 0.025	4.087ValArg: 4.087 ± 0.031	5.438ValSer: 5.438 ± 0.037	3.543ValThr: 3.543 ± 0.029	4.398ValVal: 4.398 ± 0.037	0.999ValTrp: 0.999 ± 0.012	1.788ValTyr: 1.788 ± 0.02	0.0ValXaa: 0.0 ± 0.0
Trp	1.147TrpAla: 1.147 ± 0.015	0.251TrpCys: 0.251 ± 0.008	0.899TrpAsp: 0.899 ± 0.017	0.757TrpGlu: 0.757 ± 0.014	0.517TrpPhe: 0.517 ± 0.011	0.958TrpGly: 0.958 ± 0.016	0.366TrpHis: 0.366 ± 0.009	0.752TrpIle: 0.752 ± 0.013	0.677TrpLys: 0.677 ± 0.013	1.269TrpLeu: 1.269 ± 0.018	0.385TrpMet: 0.385 ± 0.01	0.611TrpAsn: 0.611 ± 0.012	0.702TrpPro: 0.702 ± 0.013	0.454TrpGln: 0.454 ± 0.009	0.999TrpArg: 0.999 ± 0.016	1.215TrpSer: 1.215 ± 0.017	0.911TrpThr: 0.911 ± 0.014	0.975TrpVal: 0.975 ± 0.016	0.276TrpTrp: 0.276 ± 0.009	0.404TrpTyr: 0.404 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.185TyrAla: 2.185 ± 0.022	0.448TyrCys: 0.448 ± 0.011	1.501TyrAsp: 1.501 ± 0.021	1.372TyrGlu: 1.372 ± 0.017	1.055TyrPhe: 1.055 ± 0.015	1.902TyrGly: 1.902 ± 0.028	0.756TyrHis: 0.756 ± 0.015	1.431TyrIle: 1.431 ± 0.019	1.033TyrLys: 1.033 ± 0.015	2.464TyrLeu: 2.464 ± 0.028	0.608TyrMet: 0.608 ± 0.012	0.988TyrAsn: 0.988 ± 0.016	1.622TyrPro: 1.622 ± 0.026	1.009TyrGln: 1.009 ± 0.016	1.693TyrArg: 1.693 ± 0.025	2.261TyrSer: 2.261 ± 0.026	1.7TyrThr: 1.7 ± 0.021	1.708TyrVal: 1.708 ± 0.022	0.414TyrTrp: 0.414 ± 0.01	0.812TyrTyr: 0.812 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 10482 proteins (4287830 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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