Human parechovirus 2 (strain Williamson) (HPeV-2) (Echovirus 23)
Taxonomy: Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes; Picornavirales; Picornaviridae; Parechovirus; Parechovirus A; Human parechovirus 2
Average proteome isoelectric point is 5.89
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Virtual 2D-PAGE plot for 1 proteins (isoelectric point calculated using IPC2_protein)
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Summary statistics related to proteome-wise predictions
Protein with the lowest isoelectric point:
>sp|O73556|POLG_HPE2W Genome polyprotein OS=Human parechovirus 2 (strain Williamson) OX=122962 PE=3 SV=1
MM1 pKa = 7.1EE2 pKa = 5.4TIKK5 pKa = 10.88SIADD9 pKa = 3.36MATGVTKK16 pKa = 10.44TIDD19 pKa = 3.16ATINSVNEE27 pKa = 4.17IITNTDD33 pKa = 2.91NASGGDD39 pKa = 3.66ILTKK43 pKa = 10.68VADD46 pKa = 4.17DD47 pKa = 4.05ASNILGPNCYY57 pKa = 9.06ATTSEE62 pKa = 4.71PEE64 pKa = 4.07NKK66 pKa = 10.0DD67 pKa = 3.16VVQATTTVNTTNLTQHH83 pKa = 7.01PSAPTLPFTPDD94 pKa = 3.48FSNVDD99 pKa = 3.79TFHH102 pKa = 8.47SMAYY106 pKa = 8.4DD107 pKa = 3.36TTTGSKK113 pKa = 10.42NPNKK117 pKa = 10.02LVRR120 pKa = 11.84LTTHH124 pKa = 6.24AWASTLQRR132 pKa = 11.84GHH134 pKa = 6.42QIDD137 pKa = 4.44HH138 pKa = 6.49VNLPVDD144 pKa = 4.41FWDD147 pKa = 4.0EE148 pKa = 3.97QRR150 pKa = 11.84KK151 pKa = 7.67PAYY154 pKa = 9.98GHH156 pKa = 6.7AKK158 pKa = 8.59YY159 pKa = 9.62FAAVRR164 pKa = 11.84CGFHH168 pKa = 6.55FQVQVNVNQGTAGSALVVYY187 pKa = 9.09EE188 pKa = 4.27PKK190 pKa = 10.56PVVDD194 pKa = 3.6YY195 pKa = 11.55DD196 pKa = 3.46KK197 pKa = 11.27DD198 pKa = 3.93LEE200 pKa = 4.62FGAFTNLPHH209 pKa = 8.42VLMNLAEE216 pKa = 4.24TTQADD221 pKa = 3.67LCIPYY226 pKa = 10.25VADD229 pKa = 3.45TNYY232 pKa = 10.33VKK234 pKa = 10.06TDD236 pKa = 3.29SSDD239 pKa = 3.22LGQLKK244 pKa = 10.45VYY246 pKa = 10.0VWTPLSIPSGSSNQVDD262 pKa = 3.92VTILGSLLQLDD273 pKa = 4.55FQNPRR278 pKa = 11.84VYY280 pKa = 10.45GQNVDD285 pKa = 3.61IYY287 pKa = 9.88DD288 pKa = 3.95TAPSKK293 pKa = 10.28PIPLRR298 pKa = 11.84KK299 pKa = 7.99TKK301 pKa = 10.49YY302 pKa = 8.77LTMSTKK308 pKa = 10.68YY309 pKa = 9.45KK310 pKa = 7.12WTRR313 pKa = 11.84NKK315 pKa = 9.99VDD317 pKa = 3.08IAEE320 pKa = 4.99GPGSMNMANVLSTTAAQSVALVGEE344 pKa = 4.2RR345 pKa = 11.84AFYY348 pKa = 10.58DD349 pKa = 3.49PRR351 pKa = 11.84TAGSKK356 pKa = 10.44SRR358 pKa = 11.84FDD360 pKa = 4.03DD361 pKa = 3.85LVKK364 pKa = 10.36ISQLFSVMADD374 pKa = 3.02STTPSANHH382 pKa = 7.06GIDD385 pKa = 3.05QKK387 pKa = 11.8GYY389 pKa = 9.7FKK391 pKa = 10.54WSANSDD397 pKa = 3.36PQAIVHH403 pKa = 6.41RR404 pKa = 11.84NLVHH408 pKa = 7.46LNLFPNLKK416 pKa = 10.02VFEE419 pKa = 4.24NSYY422 pKa = 10.94SYY424 pKa = 11.1FRR426 pKa = 11.84GSLIIRR432 pKa = 11.84LSVYY436 pKa = 10.53ASTFNRR442 pKa = 11.84GRR444 pKa = 11.84LNGFFPNSSTDD455 pKa = 3.28EE456 pKa = 3.94TSEE459 pKa = 3.82IDD461 pKa = 3.29NAIYY465 pKa = 8.45TICDD469 pKa = 3.05IGSDD473 pKa = 3.4NSFEE477 pKa = 3.83ITIPYY482 pKa = 9.85SFSTWMRR489 pKa = 11.84KK490 pKa = 6.8THH492 pKa = 6.15GKK494 pKa = 9.53PIGLFQIEE502 pKa = 4.38VLNRR506 pKa = 11.84LTYY509 pKa = 10.5NYY511 pKa = 10.37SSPNEE516 pKa = 4.16VYY518 pKa = 10.8CIVQGKK524 pKa = 8.26MGQDD528 pKa = 2.78AKK530 pKa = 10.45FFCPTGSLVTFQNSWGSQMDD550 pKa = 3.95LTDD553 pKa = 4.21PLCIEE558 pKa = 5.51DD559 pKa = 4.21SVEE562 pKa = 4.05DD563 pKa = 3.95CKK565 pKa = 10.67QTITPTEE572 pKa = 4.24LGLTSAQDD580 pKa = 3.98DD581 pKa = 4.6GPLGNDD587 pKa = 3.01KK588 pKa = 10.88PNYY591 pKa = 9.05FLNFKK596 pKa = 10.56SMNVDD601 pKa = 2.91IFTVSHH607 pKa = 5.95TKK609 pKa = 10.03VDD611 pKa = 4.22NIFGRR616 pKa = 11.84AWFAHH621 pKa = 4.71VHH623 pKa = 6.61DD624 pKa = 4.72FTNDD628 pKa = 3.45GLWRR632 pKa = 11.84QGLEE636 pKa = 4.16FPKK639 pKa = 9.94EE640 pKa = 3.83GHH642 pKa = 6.33GALSLLFAYY651 pKa = 7.5FTGEE655 pKa = 4.02LNIHH659 pKa = 5.6VLFLSDD665 pKa = 3.84RR666 pKa = 11.84GFLRR670 pKa = 11.84VGHH673 pKa = 6.39TYY675 pKa = 9.16DD676 pKa = 3.53TEE678 pKa = 4.42TNRR681 pKa = 11.84TNFLSSSGIITVPAGEE697 pKa = 4.17QMTLSVPSYY706 pKa = 10.4SNKK709 pKa = 9.43PLRR712 pKa = 11.84TVRR715 pKa = 11.84SSNALGYY722 pKa = 9.46LLCKK726 pKa = 9.93PLLTGTSSGRR736 pKa = 11.84IEE738 pKa = 4.06IFLSLRR744 pKa = 11.84CPNFFFPLPAPKK756 pKa = 9.73PATRR760 pKa = 11.84KK761 pKa = 9.58YY762 pKa = 10.61RR763 pKa = 11.84GDD765 pKa = 3.39LATWSDD771 pKa = 3.44QSPYY775 pKa = 10.3GRR777 pKa = 11.84QGKK780 pKa = 8.28KK781 pKa = 8.46QLMKK785 pKa = 10.57LAYY788 pKa = 9.8LDD790 pKa = 3.3RR791 pKa = 11.84GFYY794 pKa = 9.13KK795 pKa = 10.31HH796 pKa = 6.03YY797 pKa = 10.32GIVVGDD803 pKa = 4.5DD804 pKa = 3.69VYY806 pKa = 11.6QLDD809 pKa = 3.92SDD811 pKa = 5.8DD812 pKa = 3.91IFKK815 pKa = 9.46TALTGKK821 pKa = 10.39AKK823 pKa = 8.95FTKK826 pKa = 9.74TRR828 pKa = 11.84LTPDD832 pKa = 2.7WVVEE836 pKa = 4.22EE837 pKa = 4.43EE838 pKa = 4.71CEE840 pKa = 4.22LDD842 pKa = 3.58YY843 pKa = 11.32FRR845 pKa = 11.84IKK847 pKa = 10.79YY848 pKa = 10.24LEE850 pKa = 4.06SSVNSEE856 pKa = 4.98HH857 pKa = 7.22IFSVDD862 pKa = 3.45NNCEE866 pKa = 4.07TIAKK870 pKa = 9.82DD871 pKa = 3.03IFGSHH876 pKa = 6.48SLSQHH881 pKa = 4.42QQIGLIGTILLTAGLMSTIKK901 pKa = 10.08TPVNPTTIKK910 pKa = 10.69EE911 pKa = 4.36FFNHH915 pKa = 7.16AIEE918 pKa = 4.73GDD920 pKa = 3.86EE921 pKa = 4.14QGLSLLVQKK930 pKa = 9.44CTTFFSSAATEE941 pKa = 4.31LLDD944 pKa = 3.76NDD946 pKa = 4.08LVKK949 pKa = 10.64FIIKK953 pKa = 9.57ILVRR957 pKa = 11.84ILCYY961 pKa = 9.58MVLYY965 pKa = 9.5CHH967 pKa = 7.01KK968 pKa = 10.47PNILTTACLSTLLVMDD984 pKa = 4.13VTSSSVLSPSCKK996 pKa = 10.58ALMQCLMDD1004 pKa = 4.76GDD1006 pKa = 4.18VKK1008 pKa = 10.98KK1009 pKa = 10.53LAEE1012 pKa = 4.22VVAEE1016 pKa = 4.31SMSNTDD1022 pKa = 3.39DD1023 pKa = 5.99DD1024 pKa = 4.85EE1025 pKa = 5.71IKK1027 pKa = 10.74EE1028 pKa = 4.19QICDD1032 pKa = 3.4TVKK1035 pKa = 9.38YY1036 pKa = 8.64TKK1038 pKa = 10.32QILSNQGPFKK1048 pKa = 10.75GFNEE1052 pKa = 3.59ISTAFRR1058 pKa = 11.84HH1059 pKa = 5.54IDD1061 pKa = 2.73WWIQTLLKK1069 pKa = 10.26IKK1071 pKa = 10.87DD1072 pKa = 3.5MVLSVFKK1079 pKa = 10.7PSVEE1083 pKa = 3.71KK1084 pKa = 10.68RR1085 pKa = 11.84AVEE1088 pKa = 3.54WLEE1091 pKa = 3.63RR1092 pKa = 11.84NKK1094 pKa = 10.75EE1095 pKa = 4.27HH1096 pKa = 6.47VCSILDD1102 pKa = 3.61YY1103 pKa = 11.19ASDD1106 pKa = 4.22IIVKK1110 pKa = 10.6SKK1112 pKa = 11.0DD1113 pKa = 3.15QTKK1116 pKa = 9.83MKK1118 pKa = 9.17TQEE1121 pKa = 3.58FYY1123 pKa = 11.02QRR1125 pKa = 11.84YY1126 pKa = 8.9NDD1128 pKa = 4.04CLSKK1132 pKa = 10.5FKK1134 pKa = 10.46PIMAMCFRR1142 pKa = 11.84SCHH1145 pKa = 5.26NSISNTVYY1153 pKa = 11.05RR1154 pKa = 11.84LFQEE1158 pKa = 4.75LARR1161 pKa = 11.84IPNRR1165 pKa = 11.84MATQNDD1171 pKa = 5.23LIRR1174 pKa = 11.84VEE1176 pKa = 5.3PIGIWIQGEE1185 pKa = 4.03PGQGKK1190 pKa = 9.58SFLTHH1195 pKa = 6.13TLSKK1199 pKa = 10.43QLQKK1203 pKa = 9.82TCGLQGIYY1211 pKa = 10.15TNPTASEE1218 pKa = 4.03FMDD1221 pKa = 5.61GYY1223 pKa = 11.17DD1224 pKa = 3.42NQDD1227 pKa = 2.26IHH1229 pKa = 8.84LIDD1232 pKa = 5.54DD1233 pKa = 4.85LGQTRR1238 pKa = 11.84KK1239 pKa = 9.95EE1240 pKa = 3.53RR1241 pKa = 11.84DD1242 pKa = 2.84IEE1244 pKa = 4.21MLCNCISSDD1253 pKa = 3.67PDD1255 pKa = 3.49IVPMAHH1261 pKa = 6.85LEE1263 pKa = 4.28EE1264 pKa = 4.96KK1265 pKa = 10.95GKK1267 pKa = 10.65FYY1269 pKa = 10.64TSKK1272 pKa = 10.95LVIATTNKK1280 pKa = 9.44PDD1282 pKa = 3.66FSSTVLLDD1290 pKa = 3.19SGALRR1295 pKa = 11.84RR1296 pKa = 11.84RR1297 pKa = 11.84FPYY1300 pKa = 10.1IMHH1303 pKa = 6.27IRR1305 pKa = 11.84AAKK1308 pKa = 9.87HH1309 pKa = 4.44YY1310 pKa = 9.81SKK1312 pKa = 10.67SGKK1315 pKa = 10.35LNVSQAMPHH1324 pKa = 6.01MSTGEE1329 pKa = 3.84CWEE1332 pKa = 3.98VSKK1335 pKa = 11.23NGRR1338 pKa = 11.84DD1339 pKa = 3.31WEE1341 pKa = 4.31TLKK1344 pKa = 11.15LKK1346 pKa = 10.5EE1347 pKa = 5.18LIDD1350 pKa = 5.18KK1351 pKa = 9.17ITVDD1355 pKa = 3.66YY1356 pKa = 10.61KK1357 pKa = 11.26EE1358 pKa = 5.47RR1359 pKa = 11.84IANYY1363 pKa = 7.57NTWKK1367 pKa = 10.41KK1368 pKa = 9.9QLEE1371 pKa = 4.35DD1372 pKa = 3.46QTLDD1376 pKa = 3.87DD1377 pKa = 5.34LDD1379 pKa = 4.95DD1380 pKa = 3.97AVSYY1384 pKa = 10.61IKK1386 pKa = 10.54HH1387 pKa = 6.43NYY1389 pKa = 8.4PDD1391 pKa = 5.49AIPYY1395 pKa = 9.26IDD1397 pKa = 4.35EE1398 pKa = 4.15YY1399 pKa = 11.82LNIEE1403 pKa = 4.2MSTLIEE1409 pKa = 3.92QMEE1412 pKa = 4.28AFIEE1416 pKa = 4.24PKK1418 pKa = 10.23PSVFKK1423 pKa = 11.02CFASRR1428 pKa = 11.84VGDD1431 pKa = 3.9KK1432 pKa = 10.43IKK1434 pKa = 10.09EE1435 pKa = 3.89ASRR1438 pKa = 11.84EE1439 pKa = 4.13VVKK1442 pKa = 10.58WFSDD1446 pKa = 3.24KK1447 pKa = 10.87LKK1449 pKa = 11.23SMLNFVEE1456 pKa = 5.39RR1457 pKa = 11.84NKK1459 pKa = 10.98AWLTVVSAVTSAIGILLLVTKK1480 pKa = 10.21IFKK1483 pKa = 10.52KK1484 pKa = 10.7EE1485 pKa = 3.65EE1486 pKa = 4.31SKK1488 pKa = 11.26DD1489 pKa = 3.36EE1490 pKa = 3.97RR1491 pKa = 11.84AYY1493 pKa = 11.45NPTLPVAKK1501 pKa = 9.81PKK1503 pKa = 9.87GTFPVSQRR1511 pKa = 11.84EE1512 pKa = 4.36FKK1514 pKa = 11.22NEE1516 pKa = 3.52APYY1519 pKa = 10.73DD1520 pKa = 3.79GQLEE1524 pKa = 4.54HH1525 pKa = 7.34IISQMAYY1532 pKa = 7.56ITGSTTGHH1540 pKa = 5.99ITHH1543 pKa = 7.16CAGYY1547 pKa = 9.19QHH1549 pKa = 7.36DD1550 pKa = 4.69EE1551 pKa = 4.6IILHH1555 pKa = 5.29GHH1557 pKa = 5.39SIKK1560 pKa = 10.85YY1561 pKa = 10.14LEE1563 pKa = 4.24QEE1565 pKa = 4.25EE1566 pKa = 4.75EE1567 pKa = 4.11LTLHH1571 pKa = 6.19YY1572 pKa = 9.96KK1573 pKa = 10.74NKK1575 pKa = 9.63VFPIEE1580 pKa = 4.19QPSVTQVTLGGKK1592 pKa = 9.46PMDD1595 pKa = 4.1LAIVKK1600 pKa = 9.99CKK1602 pKa = 10.71LPFRR1606 pKa = 11.84FKK1608 pKa = 10.92KK1609 pKa = 9.64NSKK1612 pKa = 10.37YY1613 pKa = 8.4YY1614 pKa = 7.95TNKK1617 pKa = 10.01IGTEE1621 pKa = 3.93SMLIWMTEE1629 pKa = 3.44QGIITKK1635 pKa = 9.47EE1636 pKa = 4.07VQRR1639 pKa = 11.84VHH1641 pKa = 6.5HH1642 pKa = 6.55SGGIKK1647 pKa = 8.83TRR1649 pKa = 11.84EE1650 pKa = 4.17GTEE1653 pKa = 3.83STKK1656 pKa = 10.53TISYY1660 pKa = 7.54TVKK1663 pKa = 10.09SCKK1666 pKa = 10.15GMCGGLLISKK1676 pKa = 10.17VEE1678 pKa = 4.17GNFKK1682 pKa = 10.38ILGMHH1687 pKa = 6.63IAGNGEE1693 pKa = 3.97MGVAIPFNFLKK1704 pKa = 10.85NDD1706 pKa = 3.28MSDD1709 pKa = 3.06QGIVTEE1715 pKa = 4.2VTPIQPMYY1723 pKa = 10.67INTKK1727 pKa = 7.79SQIHH1731 pKa = 6.37KK1732 pKa = 9.61SPVYY1736 pKa = 10.05GAVEE1740 pKa = 4.4VKK1742 pKa = 9.79MGPAVLSKK1750 pKa = 10.8SDD1752 pKa = 3.37TRR1754 pKa = 11.84LEE1756 pKa = 4.16EE1757 pKa = 4.34PVDD1760 pKa = 3.89CLVKK1764 pKa = 10.58KK1765 pKa = 10.31SASKK1769 pKa = 10.27YY1770 pKa = 9.52RR1771 pKa = 11.84VNKK1774 pKa = 9.43FQVNNEE1780 pKa = 3.27LWQGVKK1786 pKa = 10.43ACVKK1790 pKa = 10.38SKK1792 pKa = 9.88FRR1794 pKa = 11.84EE1795 pKa = 3.9IFGVNGIVDD1804 pKa = 4.36MKK1806 pKa = 10.18TAILGTSHH1814 pKa = 6.4VNSMDD1819 pKa = 3.41LSTSAGYY1826 pKa = 10.81SFVKK1830 pKa = 10.17SGYY1833 pKa = 9.0KK1834 pKa = 10.14KK1835 pKa = 10.28KK1836 pKa = 10.67DD1837 pKa = 3.95LICLEE1842 pKa = 4.44PFSVSPMLEE1851 pKa = 3.69KK1852 pKa = 10.49LVQEE1856 pKa = 4.64KK1857 pKa = 9.15FHH1859 pKa = 6.72NLLKK1863 pKa = 10.72GNQITTIFNTCLKK1876 pKa = 10.92DD1877 pKa = 3.65EE1878 pKa = 4.38LRR1880 pKa = 11.84KK1881 pKa = 9.78LDD1883 pKa = 4.58KK1884 pKa = 10.69IATGKK1889 pKa = 7.31TRR1891 pKa = 11.84CIEE1894 pKa = 3.93ACEE1897 pKa = 3.54IDD1899 pKa = 3.7YY1900 pKa = 11.02CIVYY1904 pKa = 9.99RR1905 pKa = 11.84MIMMEE1910 pKa = 4.57IYY1912 pKa = 10.55DD1913 pKa = 5.04KK1914 pKa = 10.61IYY1916 pKa = 8.81QTPCYY1921 pKa = 10.02YY1922 pKa = 10.63SGLAVGINPYY1932 pKa = 10.2RR1933 pKa = 11.84DD1934 pKa = 2.66WHH1936 pKa = 6.28FMINALNDD1944 pKa = 3.2YY1945 pKa = 9.38NYY1947 pKa = 10.75EE1948 pKa = 3.93MDD1950 pKa = 3.36YY1951 pKa = 11.03SQYY1954 pKa = 11.17DD1955 pKa = 3.59GSLSSMLLWEE1965 pKa = 4.59AVQVLAYY1972 pKa = 10.51CHH1974 pKa = 6.98DD1975 pKa = 4.14SPDD1978 pKa = 4.91LVMQLHH1984 pKa = 6.31KK1985 pKa = 10.58PVIDD1989 pKa = 3.67SDD1991 pKa = 3.66HH1992 pKa = 6.72VVFNEE1997 pKa = 3.18RR1998 pKa = 11.84WLIHH2002 pKa = 6.16GGMPSGSPCTTVLNSLCNLMMCIYY2026 pKa = 6.85TTNLISPGIDD2036 pKa = 3.25CLPIVYY2042 pKa = 10.12GDD2044 pKa = 4.26DD2045 pKa = 4.19VILSLDD2051 pKa = 3.64KK2052 pKa = 10.86EE2053 pKa = 4.34IEE2055 pKa = 4.06PEE2057 pKa = 3.79RR2058 pKa = 11.84LQSIMAEE2065 pKa = 4.11SFGAEE2070 pKa = 3.91VTGSRR2075 pKa = 11.84KK2076 pKa = 10.06DD2077 pKa = 3.48EE2078 pKa = 4.44PPSLKK2083 pKa = 10.06PRR2085 pKa = 11.84MEE2087 pKa = 3.92VEE2089 pKa = 3.72FLKK2092 pKa = 10.66RR2093 pKa = 11.84KK2094 pKa = 9.15PGYY2097 pKa = 9.63FPEE2100 pKa = 4.27STFIVGKK2107 pKa = 10.48LDD2109 pKa = 3.55TEE2111 pKa = 4.15NMIQHH2116 pKa = 6.55LMWMKK2121 pKa = 10.61NFSTFKK2127 pKa = 10.53QQLQSYY2133 pKa = 9.99LMEE2136 pKa = 5.0LCLHH2140 pKa = 6.56GKK2142 pKa = 8.14DD2143 pKa = 3.81TYY2145 pKa = 9.11QHH2147 pKa = 5.5YY2148 pKa = 11.21VKK2150 pKa = 10.46ILNPYY2155 pKa = 8.43LKK2157 pKa = 9.58EE2158 pKa = 3.8WNIPVDD2164 pKa = 3.94DD2165 pKa = 4.39YY2166 pKa = 11.82EE2167 pKa = 4.43VVIGKK2172 pKa = 8.12LVPMVFDD2179 pKa = 4.07
MM1 pKa = 7.1EE2 pKa = 5.4TIKK5 pKa = 10.88SIADD9 pKa = 3.36MATGVTKK16 pKa = 10.44TIDD19 pKa = 3.16ATINSVNEE27 pKa = 4.17IITNTDD33 pKa = 2.91NASGGDD39 pKa = 3.66ILTKK43 pKa = 10.68VADD46 pKa = 4.17DD47 pKa = 4.05ASNILGPNCYY57 pKa = 9.06ATTSEE62 pKa = 4.71PEE64 pKa = 4.07NKK66 pKa = 10.0DD67 pKa = 3.16VVQATTTVNTTNLTQHH83 pKa = 7.01PSAPTLPFTPDD94 pKa = 3.48FSNVDD99 pKa = 3.79TFHH102 pKa = 8.47SMAYY106 pKa = 8.4DD107 pKa = 3.36TTTGSKK113 pKa = 10.42NPNKK117 pKa = 10.02LVRR120 pKa = 11.84LTTHH124 pKa = 6.24AWASTLQRR132 pKa = 11.84GHH134 pKa = 6.42QIDD137 pKa = 4.44HH138 pKa = 6.49VNLPVDD144 pKa = 4.41FWDD147 pKa = 4.0EE148 pKa = 3.97QRR150 pKa = 11.84KK151 pKa = 7.67PAYY154 pKa = 9.98GHH156 pKa = 6.7AKK158 pKa = 8.59YY159 pKa = 9.62FAAVRR164 pKa = 11.84CGFHH168 pKa = 6.55FQVQVNVNQGTAGSALVVYY187 pKa = 9.09EE188 pKa = 4.27PKK190 pKa = 10.56PVVDD194 pKa = 3.6YY195 pKa = 11.55DD196 pKa = 3.46KK197 pKa = 11.27DD198 pKa = 3.93LEE200 pKa = 4.62FGAFTNLPHH209 pKa = 8.42VLMNLAEE216 pKa = 4.24TTQADD221 pKa = 3.67LCIPYY226 pKa = 10.25VADD229 pKa = 3.45TNYY232 pKa = 10.33VKK234 pKa = 10.06TDD236 pKa = 3.29SSDD239 pKa = 3.22LGQLKK244 pKa = 10.45VYY246 pKa = 10.0VWTPLSIPSGSSNQVDD262 pKa = 3.92VTILGSLLQLDD273 pKa = 4.55FQNPRR278 pKa = 11.84VYY280 pKa = 10.45GQNVDD285 pKa = 3.61IYY287 pKa = 9.88DD288 pKa = 3.95TAPSKK293 pKa = 10.28PIPLRR298 pKa = 11.84KK299 pKa = 7.99TKK301 pKa = 10.49YY302 pKa = 8.77LTMSTKK308 pKa = 10.68YY309 pKa = 9.45KK310 pKa = 7.12WTRR313 pKa = 11.84NKK315 pKa = 9.99VDD317 pKa = 3.08IAEE320 pKa = 4.99GPGSMNMANVLSTTAAQSVALVGEE344 pKa = 4.2RR345 pKa = 11.84AFYY348 pKa = 10.58DD349 pKa = 3.49PRR351 pKa = 11.84TAGSKK356 pKa = 10.44SRR358 pKa = 11.84FDD360 pKa = 4.03DD361 pKa = 3.85LVKK364 pKa = 10.36ISQLFSVMADD374 pKa = 3.02STTPSANHH382 pKa = 7.06GIDD385 pKa = 3.05QKK387 pKa = 11.8GYY389 pKa = 9.7FKK391 pKa = 10.54WSANSDD397 pKa = 3.36PQAIVHH403 pKa = 6.41RR404 pKa = 11.84NLVHH408 pKa = 7.46LNLFPNLKK416 pKa = 10.02VFEE419 pKa = 4.24NSYY422 pKa = 10.94SYY424 pKa = 11.1FRR426 pKa = 11.84GSLIIRR432 pKa = 11.84LSVYY436 pKa = 10.53ASTFNRR442 pKa = 11.84GRR444 pKa = 11.84LNGFFPNSSTDD455 pKa = 3.28EE456 pKa = 3.94TSEE459 pKa = 3.82IDD461 pKa = 3.29NAIYY465 pKa = 8.45TICDD469 pKa = 3.05IGSDD473 pKa = 3.4NSFEE477 pKa = 3.83ITIPYY482 pKa = 9.85SFSTWMRR489 pKa = 11.84KK490 pKa = 6.8THH492 pKa = 6.15GKK494 pKa = 9.53PIGLFQIEE502 pKa = 4.38VLNRR506 pKa = 11.84LTYY509 pKa = 10.5NYY511 pKa = 10.37SSPNEE516 pKa = 4.16VYY518 pKa = 10.8CIVQGKK524 pKa = 8.26MGQDD528 pKa = 2.78AKK530 pKa = 10.45FFCPTGSLVTFQNSWGSQMDD550 pKa = 3.95LTDD553 pKa = 4.21PLCIEE558 pKa = 5.51DD559 pKa = 4.21SVEE562 pKa = 4.05DD563 pKa = 3.95CKK565 pKa = 10.67QTITPTEE572 pKa = 4.24LGLTSAQDD580 pKa = 3.98DD581 pKa = 4.6GPLGNDD587 pKa = 3.01KK588 pKa = 10.88PNYY591 pKa = 9.05FLNFKK596 pKa = 10.56SMNVDD601 pKa = 2.91IFTVSHH607 pKa = 5.95TKK609 pKa = 10.03VDD611 pKa = 4.22NIFGRR616 pKa = 11.84AWFAHH621 pKa = 4.71VHH623 pKa = 6.61DD624 pKa = 4.72FTNDD628 pKa = 3.45GLWRR632 pKa = 11.84QGLEE636 pKa = 4.16FPKK639 pKa = 9.94EE640 pKa = 3.83GHH642 pKa = 6.33GALSLLFAYY651 pKa = 7.5FTGEE655 pKa = 4.02LNIHH659 pKa = 5.6VLFLSDD665 pKa = 3.84RR666 pKa = 11.84GFLRR670 pKa = 11.84VGHH673 pKa = 6.39TYY675 pKa = 9.16DD676 pKa = 3.53TEE678 pKa = 4.42TNRR681 pKa = 11.84TNFLSSSGIITVPAGEE697 pKa = 4.17QMTLSVPSYY706 pKa = 10.4SNKK709 pKa = 9.43PLRR712 pKa = 11.84TVRR715 pKa = 11.84SSNALGYY722 pKa = 9.46LLCKK726 pKa = 9.93PLLTGTSSGRR736 pKa = 11.84IEE738 pKa = 4.06IFLSLRR744 pKa = 11.84CPNFFFPLPAPKK756 pKa = 9.73PATRR760 pKa = 11.84KK761 pKa = 9.58YY762 pKa = 10.61RR763 pKa = 11.84GDD765 pKa = 3.39LATWSDD771 pKa = 3.44QSPYY775 pKa = 10.3GRR777 pKa = 11.84QGKK780 pKa = 8.28KK781 pKa = 8.46QLMKK785 pKa = 10.57LAYY788 pKa = 9.8LDD790 pKa = 3.3RR791 pKa = 11.84GFYY794 pKa = 9.13KK795 pKa = 10.31HH796 pKa = 6.03YY797 pKa = 10.32GIVVGDD803 pKa = 4.5DD804 pKa = 3.69VYY806 pKa = 11.6QLDD809 pKa = 3.92SDD811 pKa = 5.8DD812 pKa = 3.91IFKK815 pKa = 9.46TALTGKK821 pKa = 10.39AKK823 pKa = 8.95FTKK826 pKa = 9.74TRR828 pKa = 11.84LTPDD832 pKa = 2.7WVVEE836 pKa = 4.22EE837 pKa = 4.43EE838 pKa = 4.71CEE840 pKa = 4.22LDD842 pKa = 3.58YY843 pKa = 11.32FRR845 pKa = 11.84IKK847 pKa = 10.79YY848 pKa = 10.24LEE850 pKa = 4.06SSVNSEE856 pKa = 4.98HH857 pKa = 7.22IFSVDD862 pKa = 3.45NNCEE866 pKa = 4.07TIAKK870 pKa = 9.82DD871 pKa = 3.03IFGSHH876 pKa = 6.48SLSQHH881 pKa = 4.42QQIGLIGTILLTAGLMSTIKK901 pKa = 10.08TPVNPTTIKK910 pKa = 10.69EE911 pKa = 4.36FFNHH915 pKa = 7.16AIEE918 pKa = 4.73GDD920 pKa = 3.86EE921 pKa = 4.14QGLSLLVQKK930 pKa = 9.44CTTFFSSAATEE941 pKa = 4.31LLDD944 pKa = 3.76NDD946 pKa = 4.08LVKK949 pKa = 10.64FIIKK953 pKa = 9.57ILVRR957 pKa = 11.84ILCYY961 pKa = 9.58MVLYY965 pKa = 9.5CHH967 pKa = 7.01KK968 pKa = 10.47PNILTTACLSTLLVMDD984 pKa = 4.13VTSSSVLSPSCKK996 pKa = 10.58ALMQCLMDD1004 pKa = 4.76GDD1006 pKa = 4.18VKK1008 pKa = 10.98KK1009 pKa = 10.53LAEE1012 pKa = 4.22VVAEE1016 pKa = 4.31SMSNTDD1022 pKa = 3.39DD1023 pKa = 5.99DD1024 pKa = 4.85EE1025 pKa = 5.71IKK1027 pKa = 10.74EE1028 pKa = 4.19QICDD1032 pKa = 3.4TVKK1035 pKa = 9.38YY1036 pKa = 8.64TKK1038 pKa = 10.32QILSNQGPFKK1048 pKa = 10.75GFNEE1052 pKa = 3.59ISTAFRR1058 pKa = 11.84HH1059 pKa = 5.54IDD1061 pKa = 2.73WWIQTLLKK1069 pKa = 10.26IKK1071 pKa = 10.87DD1072 pKa = 3.5MVLSVFKK1079 pKa = 10.7PSVEE1083 pKa = 3.71KK1084 pKa = 10.68RR1085 pKa = 11.84AVEE1088 pKa = 3.54WLEE1091 pKa = 3.63RR1092 pKa = 11.84NKK1094 pKa = 10.75EE1095 pKa = 4.27HH1096 pKa = 6.47VCSILDD1102 pKa = 3.61YY1103 pKa = 11.19ASDD1106 pKa = 4.22IIVKK1110 pKa = 10.6SKK1112 pKa = 11.0DD1113 pKa = 3.15QTKK1116 pKa = 9.83MKK1118 pKa = 9.17TQEE1121 pKa = 3.58FYY1123 pKa = 11.02QRR1125 pKa = 11.84YY1126 pKa = 8.9NDD1128 pKa = 4.04CLSKK1132 pKa = 10.5FKK1134 pKa = 10.46PIMAMCFRR1142 pKa = 11.84SCHH1145 pKa = 5.26NSISNTVYY1153 pKa = 11.05RR1154 pKa = 11.84LFQEE1158 pKa = 4.75LARR1161 pKa = 11.84IPNRR1165 pKa = 11.84MATQNDD1171 pKa = 5.23LIRR1174 pKa = 11.84VEE1176 pKa = 5.3PIGIWIQGEE1185 pKa = 4.03PGQGKK1190 pKa = 9.58SFLTHH1195 pKa = 6.13TLSKK1199 pKa = 10.43QLQKK1203 pKa = 9.82TCGLQGIYY1211 pKa = 10.15TNPTASEE1218 pKa = 4.03FMDD1221 pKa = 5.61GYY1223 pKa = 11.17DD1224 pKa = 3.42NQDD1227 pKa = 2.26IHH1229 pKa = 8.84LIDD1232 pKa = 5.54DD1233 pKa = 4.85LGQTRR1238 pKa = 11.84KK1239 pKa = 9.95EE1240 pKa = 3.53RR1241 pKa = 11.84DD1242 pKa = 2.84IEE1244 pKa = 4.21MLCNCISSDD1253 pKa = 3.67PDD1255 pKa = 3.49IVPMAHH1261 pKa = 6.85LEE1263 pKa = 4.28EE1264 pKa = 4.96KK1265 pKa = 10.95GKK1267 pKa = 10.65FYY1269 pKa = 10.64TSKK1272 pKa = 10.95LVIATTNKK1280 pKa = 9.44PDD1282 pKa = 3.66FSSTVLLDD1290 pKa = 3.19SGALRR1295 pKa = 11.84RR1296 pKa = 11.84RR1297 pKa = 11.84FPYY1300 pKa = 10.1IMHH1303 pKa = 6.27IRR1305 pKa = 11.84AAKK1308 pKa = 9.87HH1309 pKa = 4.44YY1310 pKa = 9.81SKK1312 pKa = 10.67SGKK1315 pKa = 10.35LNVSQAMPHH1324 pKa = 6.01MSTGEE1329 pKa = 3.84CWEE1332 pKa = 3.98VSKK1335 pKa = 11.23NGRR1338 pKa = 11.84DD1339 pKa = 3.31WEE1341 pKa = 4.31TLKK1344 pKa = 11.15LKK1346 pKa = 10.5EE1347 pKa = 5.18LIDD1350 pKa = 5.18KK1351 pKa = 9.17ITVDD1355 pKa = 3.66YY1356 pKa = 10.61KK1357 pKa = 11.26EE1358 pKa = 5.47RR1359 pKa = 11.84IANYY1363 pKa = 7.57NTWKK1367 pKa = 10.41KK1368 pKa = 9.9QLEE1371 pKa = 4.35DD1372 pKa = 3.46QTLDD1376 pKa = 3.87DD1377 pKa = 5.34LDD1379 pKa = 4.95DD1380 pKa = 3.97AVSYY1384 pKa = 10.61IKK1386 pKa = 10.54HH1387 pKa = 6.43NYY1389 pKa = 8.4PDD1391 pKa = 5.49AIPYY1395 pKa = 9.26IDD1397 pKa = 4.35EE1398 pKa = 4.15YY1399 pKa = 11.82LNIEE1403 pKa = 4.2MSTLIEE1409 pKa = 3.92QMEE1412 pKa = 4.28AFIEE1416 pKa = 4.24PKK1418 pKa = 10.23PSVFKK1423 pKa = 11.02CFASRR1428 pKa = 11.84VGDD1431 pKa = 3.9KK1432 pKa = 10.43IKK1434 pKa = 10.09EE1435 pKa = 3.89ASRR1438 pKa = 11.84EE1439 pKa = 4.13VVKK1442 pKa = 10.58WFSDD1446 pKa = 3.24KK1447 pKa = 10.87LKK1449 pKa = 11.23SMLNFVEE1456 pKa = 5.39RR1457 pKa = 11.84NKK1459 pKa = 10.98AWLTVVSAVTSAIGILLLVTKK1480 pKa = 10.21IFKK1483 pKa = 10.52KK1484 pKa = 10.7EE1485 pKa = 3.65EE1486 pKa = 4.31SKK1488 pKa = 11.26DD1489 pKa = 3.36EE1490 pKa = 3.97RR1491 pKa = 11.84AYY1493 pKa = 11.45NPTLPVAKK1501 pKa = 9.81PKK1503 pKa = 9.87GTFPVSQRR1511 pKa = 11.84EE1512 pKa = 4.36FKK1514 pKa = 11.22NEE1516 pKa = 3.52APYY1519 pKa = 10.73DD1520 pKa = 3.79GQLEE1524 pKa = 4.54HH1525 pKa = 7.34IISQMAYY1532 pKa = 7.56ITGSTTGHH1540 pKa = 5.99ITHH1543 pKa = 7.16CAGYY1547 pKa = 9.19QHH1549 pKa = 7.36DD1550 pKa = 4.69EE1551 pKa = 4.6IILHH1555 pKa = 5.29GHH1557 pKa = 5.39SIKK1560 pKa = 10.85YY1561 pKa = 10.14LEE1563 pKa = 4.24QEE1565 pKa = 4.25EE1566 pKa = 4.75EE1567 pKa = 4.11LTLHH1571 pKa = 6.19YY1572 pKa = 9.96KK1573 pKa = 10.74NKK1575 pKa = 9.63VFPIEE1580 pKa = 4.19QPSVTQVTLGGKK1592 pKa = 9.46PMDD1595 pKa = 4.1LAIVKK1600 pKa = 9.99CKK1602 pKa = 10.71LPFRR1606 pKa = 11.84FKK1608 pKa = 10.92KK1609 pKa = 9.64NSKK1612 pKa = 10.37YY1613 pKa = 8.4YY1614 pKa = 7.95TNKK1617 pKa = 10.01IGTEE1621 pKa = 3.93SMLIWMTEE1629 pKa = 3.44QGIITKK1635 pKa = 9.47EE1636 pKa = 4.07VQRR1639 pKa = 11.84VHH1641 pKa = 6.5HH1642 pKa = 6.55SGGIKK1647 pKa = 8.83TRR1649 pKa = 11.84EE1650 pKa = 4.17GTEE1653 pKa = 3.83STKK1656 pKa = 10.53TISYY1660 pKa = 7.54TVKK1663 pKa = 10.09SCKK1666 pKa = 10.15GMCGGLLISKK1676 pKa = 10.17VEE1678 pKa = 4.17GNFKK1682 pKa = 10.38ILGMHH1687 pKa = 6.63IAGNGEE1693 pKa = 3.97MGVAIPFNFLKK1704 pKa = 10.85NDD1706 pKa = 3.28MSDD1709 pKa = 3.06QGIVTEE1715 pKa = 4.2VTPIQPMYY1723 pKa = 10.67INTKK1727 pKa = 7.79SQIHH1731 pKa = 6.37KK1732 pKa = 9.61SPVYY1736 pKa = 10.05GAVEE1740 pKa = 4.4VKK1742 pKa = 9.79MGPAVLSKK1750 pKa = 10.8SDD1752 pKa = 3.37TRR1754 pKa = 11.84LEE1756 pKa = 4.16EE1757 pKa = 4.34PVDD1760 pKa = 3.89CLVKK1764 pKa = 10.58KK1765 pKa = 10.31SASKK1769 pKa = 10.27YY1770 pKa = 9.52RR1771 pKa = 11.84VNKK1774 pKa = 9.43FQVNNEE1780 pKa = 3.27LWQGVKK1786 pKa = 10.43ACVKK1790 pKa = 10.38SKK1792 pKa = 9.88FRR1794 pKa = 11.84EE1795 pKa = 3.9IFGVNGIVDD1804 pKa = 4.36MKK1806 pKa = 10.18TAILGTSHH1814 pKa = 6.4VNSMDD1819 pKa = 3.41LSTSAGYY1826 pKa = 10.81SFVKK1830 pKa = 10.17SGYY1833 pKa = 9.0KK1834 pKa = 10.14KK1835 pKa = 10.28KK1836 pKa = 10.67DD1837 pKa = 3.95LICLEE1842 pKa = 4.44PFSVSPMLEE1851 pKa = 3.69KK1852 pKa = 10.49LVQEE1856 pKa = 4.64KK1857 pKa = 9.15FHH1859 pKa = 6.72NLLKK1863 pKa = 10.72GNQITTIFNTCLKK1876 pKa = 10.92DD1877 pKa = 3.65EE1878 pKa = 4.38LRR1880 pKa = 11.84KK1881 pKa = 9.78LDD1883 pKa = 4.58KK1884 pKa = 10.69IATGKK1889 pKa = 7.31TRR1891 pKa = 11.84CIEE1894 pKa = 3.93ACEE1897 pKa = 3.54IDD1899 pKa = 3.7YY1900 pKa = 11.02CIVYY1904 pKa = 9.99RR1905 pKa = 11.84MIMMEE1910 pKa = 4.57IYY1912 pKa = 10.55DD1913 pKa = 5.04KK1914 pKa = 10.61IYY1916 pKa = 8.81QTPCYY1921 pKa = 10.02YY1922 pKa = 10.63SGLAVGINPYY1932 pKa = 10.2RR1933 pKa = 11.84DD1934 pKa = 2.66WHH1936 pKa = 6.28FMINALNDD1944 pKa = 3.2YY1945 pKa = 9.38NYY1947 pKa = 10.75EE1948 pKa = 3.93MDD1950 pKa = 3.36YY1951 pKa = 11.03SQYY1954 pKa = 11.17DD1955 pKa = 3.59GSLSSMLLWEE1965 pKa = 4.59AVQVLAYY1972 pKa = 10.51CHH1974 pKa = 6.98DD1975 pKa = 4.14SPDD1978 pKa = 4.91LVMQLHH1984 pKa = 6.31KK1985 pKa = 10.58PVIDD1989 pKa = 3.67SDD1991 pKa = 3.66HH1992 pKa = 6.72VVFNEE1997 pKa = 3.18RR1998 pKa = 11.84WLIHH2002 pKa = 6.16GGMPSGSPCTTVLNSLCNLMMCIYY2026 pKa = 6.85TTNLISPGIDD2036 pKa = 3.25CLPIVYY2042 pKa = 10.12GDD2044 pKa = 4.26DD2045 pKa = 4.19VILSLDD2051 pKa = 3.64KK2052 pKa = 10.86EE2053 pKa = 4.34IEE2055 pKa = 4.06PEE2057 pKa = 3.79RR2058 pKa = 11.84LQSIMAEE2065 pKa = 4.11SFGAEE2070 pKa = 3.91VTGSRR2075 pKa = 11.84KK2076 pKa = 10.06DD2077 pKa = 3.48EE2078 pKa = 4.44PPSLKK2083 pKa = 10.06PRR2085 pKa = 11.84MEE2087 pKa = 3.92VEE2089 pKa = 3.72FLKK2092 pKa = 10.66RR2093 pKa = 11.84KK2094 pKa = 9.15PGYY2097 pKa = 9.63FPEE2100 pKa = 4.27STFIVGKK2107 pKa = 10.48LDD2109 pKa = 3.55TEE2111 pKa = 4.15NMIQHH2116 pKa = 6.55LMWMKK2121 pKa = 10.61NFSTFKK2127 pKa = 10.53QQLQSYY2133 pKa = 9.99LMEE2136 pKa = 5.0LCLHH2140 pKa = 6.56GKK2142 pKa = 8.14DD2143 pKa = 3.81TYY2145 pKa = 9.11QHH2147 pKa = 5.5YY2148 pKa = 11.21VKK2150 pKa = 10.46ILNPYY2155 pKa = 8.43LKK2157 pKa = 9.58EE2158 pKa = 3.8WNIPVDD2164 pKa = 3.94DD2165 pKa = 4.39YY2166 pKa = 11.82EE2167 pKa = 4.43VVIGKK2172 pKa = 8.12LVPMVFDD2179 pKa = 4.07
Molecular weight: 245.87 kDa
Isoelectric point according different methods:
Protein with the highest isoelectric point:
>sp|O73556|POLG_HPE2W Genome polyprotein OS=Human parechovirus 2 (strain Williamson) OX=122962 PE=3 SV=1
MM1 pKa = 7.1EE2 pKa = 5.4TIKK5 pKa = 10.88SIADD9 pKa = 3.36MATGVTKK16 pKa = 10.44TIDD19 pKa = 3.16ATINSVNEE27 pKa = 4.17IITNTDD33 pKa = 2.91NASGGDD39 pKa = 3.66ILTKK43 pKa = 10.68VADD46 pKa = 4.17DD47 pKa = 4.05ASNILGPNCYY57 pKa = 9.06ATTSEE62 pKa = 4.71PEE64 pKa = 4.07NKK66 pKa = 10.0DD67 pKa = 3.16VVQATTTVNTTNLTQHH83 pKa = 7.01PSAPTLPFTPDD94 pKa = 3.48FSNVDD99 pKa = 3.79TFHH102 pKa = 8.47SMAYY106 pKa = 8.4DD107 pKa = 3.36TTTGSKK113 pKa = 10.42NPNKK117 pKa = 10.02LVRR120 pKa = 11.84LTTHH124 pKa = 6.24AWASTLQRR132 pKa = 11.84GHH134 pKa = 6.42QIDD137 pKa = 4.44HH138 pKa = 6.49VNLPVDD144 pKa = 4.41FWDD147 pKa = 4.0EE148 pKa = 3.97QRR150 pKa = 11.84KK151 pKa = 7.67PAYY154 pKa = 9.98GHH156 pKa = 6.7AKK158 pKa = 8.59YY159 pKa = 9.62FAAVRR164 pKa = 11.84CGFHH168 pKa = 6.55FQVQVNVNQGTAGSALVVYY187 pKa = 9.09EE188 pKa = 4.27PKK190 pKa = 10.56PVVDD194 pKa = 3.6YY195 pKa = 11.55DD196 pKa = 3.46KK197 pKa = 11.27DD198 pKa = 3.93LEE200 pKa = 4.62FGAFTNLPHH209 pKa = 8.42VLMNLAEE216 pKa = 4.24TTQADD221 pKa = 3.67LCIPYY226 pKa = 10.25VADD229 pKa = 3.45TNYY232 pKa = 10.33VKK234 pKa = 10.06TDD236 pKa = 3.29SSDD239 pKa = 3.22LGQLKK244 pKa = 10.45VYY246 pKa = 10.0VWTPLSIPSGSSNQVDD262 pKa = 3.92VTILGSLLQLDD273 pKa = 4.55FQNPRR278 pKa = 11.84VYY280 pKa = 10.45GQNVDD285 pKa = 3.61IYY287 pKa = 9.88DD288 pKa = 3.95TAPSKK293 pKa = 10.28PIPLRR298 pKa = 11.84KK299 pKa = 7.99TKK301 pKa = 10.49YY302 pKa = 8.77LTMSTKK308 pKa = 10.68YY309 pKa = 9.45KK310 pKa = 7.12WTRR313 pKa = 11.84NKK315 pKa = 9.99VDD317 pKa = 3.08IAEE320 pKa = 4.99GPGSMNMANVLSTTAAQSVALVGEE344 pKa = 4.2RR345 pKa = 11.84AFYY348 pKa = 10.58DD349 pKa = 3.49PRR351 pKa = 11.84TAGSKK356 pKa = 10.44SRR358 pKa = 11.84FDD360 pKa = 4.03DD361 pKa = 3.85LVKK364 pKa = 10.36ISQLFSVMADD374 pKa = 3.02STTPSANHH382 pKa = 7.06GIDD385 pKa = 3.05QKK387 pKa = 11.8GYY389 pKa = 9.7FKK391 pKa = 10.54WSANSDD397 pKa = 3.36PQAIVHH403 pKa = 6.41RR404 pKa = 11.84NLVHH408 pKa = 7.46LNLFPNLKK416 pKa = 10.02VFEE419 pKa = 4.24NSYY422 pKa = 10.94SYY424 pKa = 11.1FRR426 pKa = 11.84GSLIIRR432 pKa = 11.84LSVYY436 pKa = 10.53ASTFNRR442 pKa = 11.84GRR444 pKa = 11.84LNGFFPNSSTDD455 pKa = 3.28EE456 pKa = 3.94TSEE459 pKa = 3.82IDD461 pKa = 3.29NAIYY465 pKa = 8.45TICDD469 pKa = 3.05IGSDD473 pKa = 3.4NSFEE477 pKa = 3.83ITIPYY482 pKa = 9.85SFSTWMRR489 pKa = 11.84KK490 pKa = 6.8THH492 pKa = 6.15GKK494 pKa = 9.53PIGLFQIEE502 pKa = 4.38VLNRR506 pKa = 11.84LTYY509 pKa = 10.5NYY511 pKa = 10.37SSPNEE516 pKa = 4.16VYY518 pKa = 10.8CIVQGKK524 pKa = 8.26MGQDD528 pKa = 2.78AKK530 pKa = 10.45FFCPTGSLVTFQNSWGSQMDD550 pKa = 3.95LTDD553 pKa = 4.21PLCIEE558 pKa = 5.51DD559 pKa = 4.21SVEE562 pKa = 4.05DD563 pKa = 3.95CKK565 pKa = 10.67QTITPTEE572 pKa = 4.24LGLTSAQDD580 pKa = 3.98DD581 pKa = 4.6GPLGNDD587 pKa = 3.01KK588 pKa = 10.88PNYY591 pKa = 9.05FLNFKK596 pKa = 10.56SMNVDD601 pKa = 2.91IFTVSHH607 pKa = 5.95TKK609 pKa = 10.03VDD611 pKa = 4.22NIFGRR616 pKa = 11.84AWFAHH621 pKa = 4.71VHH623 pKa = 6.61DD624 pKa = 4.72FTNDD628 pKa = 3.45GLWRR632 pKa = 11.84QGLEE636 pKa = 4.16FPKK639 pKa = 9.94EE640 pKa = 3.83GHH642 pKa = 6.33GALSLLFAYY651 pKa = 7.5FTGEE655 pKa = 4.02LNIHH659 pKa = 5.6VLFLSDD665 pKa = 3.84RR666 pKa = 11.84GFLRR670 pKa = 11.84VGHH673 pKa = 6.39TYY675 pKa = 9.16DD676 pKa = 3.53TEE678 pKa = 4.42TNRR681 pKa = 11.84TNFLSSSGIITVPAGEE697 pKa = 4.17QMTLSVPSYY706 pKa = 10.4SNKK709 pKa = 9.43PLRR712 pKa = 11.84TVRR715 pKa = 11.84SSNALGYY722 pKa = 9.46LLCKK726 pKa = 9.93PLLTGTSSGRR736 pKa = 11.84IEE738 pKa = 4.06IFLSLRR744 pKa = 11.84CPNFFFPLPAPKK756 pKa = 9.73PATRR760 pKa = 11.84KK761 pKa = 9.58YY762 pKa = 10.61RR763 pKa = 11.84GDD765 pKa = 3.39LATWSDD771 pKa = 3.44QSPYY775 pKa = 10.3GRR777 pKa = 11.84QGKK780 pKa = 8.28KK781 pKa = 8.46QLMKK785 pKa = 10.57LAYY788 pKa = 9.8LDD790 pKa = 3.3RR791 pKa = 11.84GFYY794 pKa = 9.13KK795 pKa = 10.31HH796 pKa = 6.03YY797 pKa = 10.32GIVVGDD803 pKa = 4.5DD804 pKa = 3.69VYY806 pKa = 11.6QLDD809 pKa = 3.92SDD811 pKa = 5.8DD812 pKa = 3.91IFKK815 pKa = 9.46TALTGKK821 pKa = 10.39AKK823 pKa = 8.95FTKK826 pKa = 9.74TRR828 pKa = 11.84LTPDD832 pKa = 2.7WVVEE836 pKa = 4.22EE837 pKa = 4.43EE838 pKa = 4.71CEE840 pKa = 4.22LDD842 pKa = 3.58YY843 pKa = 11.32FRR845 pKa = 11.84IKK847 pKa = 10.79YY848 pKa = 10.24LEE850 pKa = 4.06SSVNSEE856 pKa = 4.98HH857 pKa = 7.22IFSVDD862 pKa = 3.45NNCEE866 pKa = 4.07TIAKK870 pKa = 9.82DD871 pKa = 3.03IFGSHH876 pKa = 6.48SLSQHH881 pKa = 4.42QQIGLIGTILLTAGLMSTIKK901 pKa = 10.08TPVNPTTIKK910 pKa = 10.69EE911 pKa = 4.36FFNHH915 pKa = 7.16AIEE918 pKa = 4.73GDD920 pKa = 3.86EE921 pKa = 4.14QGLSLLVQKK930 pKa = 9.44CTTFFSSAATEE941 pKa = 4.31LLDD944 pKa = 3.76NDD946 pKa = 4.08LVKK949 pKa = 10.64FIIKK953 pKa = 9.57ILVRR957 pKa = 11.84ILCYY961 pKa = 9.58MVLYY965 pKa = 9.5CHH967 pKa = 7.01KK968 pKa = 10.47PNILTTACLSTLLVMDD984 pKa = 4.13VTSSSVLSPSCKK996 pKa = 10.58ALMQCLMDD1004 pKa = 4.76GDD1006 pKa = 4.18VKK1008 pKa = 10.98KK1009 pKa = 10.53LAEE1012 pKa = 4.22VVAEE1016 pKa = 4.31SMSNTDD1022 pKa = 3.39DD1023 pKa = 5.99DD1024 pKa = 4.85EE1025 pKa = 5.71IKK1027 pKa = 10.74EE1028 pKa = 4.19QICDD1032 pKa = 3.4TVKK1035 pKa = 9.38YY1036 pKa = 8.64TKK1038 pKa = 10.32QILSNQGPFKK1048 pKa = 10.75GFNEE1052 pKa = 3.59ISTAFRR1058 pKa = 11.84HH1059 pKa = 5.54IDD1061 pKa = 2.73WWIQTLLKK1069 pKa = 10.26IKK1071 pKa = 10.87DD1072 pKa = 3.5MVLSVFKK1079 pKa = 10.7PSVEE1083 pKa = 3.71KK1084 pKa = 10.68RR1085 pKa = 11.84AVEE1088 pKa = 3.54WLEE1091 pKa = 3.63RR1092 pKa = 11.84NKK1094 pKa = 10.75EE1095 pKa = 4.27HH1096 pKa = 6.47VCSILDD1102 pKa = 3.61YY1103 pKa = 11.19ASDD1106 pKa = 4.22IIVKK1110 pKa = 10.6SKK1112 pKa = 11.0DD1113 pKa = 3.15QTKK1116 pKa = 9.83MKK1118 pKa = 9.17TQEE1121 pKa = 3.58FYY1123 pKa = 11.02QRR1125 pKa = 11.84YY1126 pKa = 8.9NDD1128 pKa = 4.04CLSKK1132 pKa = 10.5FKK1134 pKa = 10.46PIMAMCFRR1142 pKa = 11.84SCHH1145 pKa = 5.26NSISNTVYY1153 pKa = 11.05RR1154 pKa = 11.84LFQEE1158 pKa = 4.75LARR1161 pKa = 11.84IPNRR1165 pKa = 11.84MATQNDD1171 pKa = 5.23LIRR1174 pKa = 11.84VEE1176 pKa = 5.3PIGIWIQGEE1185 pKa = 4.03PGQGKK1190 pKa = 9.58SFLTHH1195 pKa = 6.13TLSKK1199 pKa = 10.43QLQKK1203 pKa = 9.82TCGLQGIYY1211 pKa = 10.15TNPTASEE1218 pKa = 4.03FMDD1221 pKa = 5.61GYY1223 pKa = 11.17DD1224 pKa = 3.42NQDD1227 pKa = 2.26IHH1229 pKa = 8.84LIDD1232 pKa = 5.54DD1233 pKa = 4.85LGQTRR1238 pKa = 11.84KK1239 pKa = 9.95EE1240 pKa = 3.53RR1241 pKa = 11.84DD1242 pKa = 2.84IEE1244 pKa = 4.21MLCNCISSDD1253 pKa = 3.67PDD1255 pKa = 3.49IVPMAHH1261 pKa = 6.85LEE1263 pKa = 4.28EE1264 pKa = 4.96KK1265 pKa = 10.95GKK1267 pKa = 10.65FYY1269 pKa = 10.64TSKK1272 pKa = 10.95LVIATTNKK1280 pKa = 9.44PDD1282 pKa = 3.66FSSTVLLDD1290 pKa = 3.19SGALRR1295 pKa = 11.84RR1296 pKa = 11.84RR1297 pKa = 11.84FPYY1300 pKa = 10.1IMHH1303 pKa = 6.27IRR1305 pKa = 11.84AAKK1308 pKa = 9.87HH1309 pKa = 4.44YY1310 pKa = 9.81SKK1312 pKa = 10.67SGKK1315 pKa = 10.35LNVSQAMPHH1324 pKa = 6.01MSTGEE1329 pKa = 3.84CWEE1332 pKa = 3.98VSKK1335 pKa = 11.23NGRR1338 pKa = 11.84DD1339 pKa = 3.31WEE1341 pKa = 4.31TLKK1344 pKa = 11.15LKK1346 pKa = 10.5EE1347 pKa = 5.18LIDD1350 pKa = 5.18KK1351 pKa = 9.17ITVDD1355 pKa = 3.66YY1356 pKa = 10.61KK1357 pKa = 11.26EE1358 pKa = 5.47RR1359 pKa = 11.84IANYY1363 pKa = 7.57NTWKK1367 pKa = 10.41KK1368 pKa = 9.9QLEE1371 pKa = 4.35DD1372 pKa = 3.46QTLDD1376 pKa = 3.87DD1377 pKa = 5.34LDD1379 pKa = 4.95DD1380 pKa = 3.97AVSYY1384 pKa = 10.61IKK1386 pKa = 10.54HH1387 pKa = 6.43NYY1389 pKa = 8.4PDD1391 pKa = 5.49AIPYY1395 pKa = 9.26IDD1397 pKa = 4.35EE1398 pKa = 4.15YY1399 pKa = 11.82LNIEE1403 pKa = 4.2MSTLIEE1409 pKa = 3.92QMEE1412 pKa = 4.28AFIEE1416 pKa = 4.24PKK1418 pKa = 10.23PSVFKK1423 pKa = 11.02CFASRR1428 pKa = 11.84VGDD1431 pKa = 3.9KK1432 pKa = 10.43IKK1434 pKa = 10.09EE1435 pKa = 3.89ASRR1438 pKa = 11.84EE1439 pKa = 4.13VVKK1442 pKa = 10.58WFSDD1446 pKa = 3.24KK1447 pKa = 10.87LKK1449 pKa = 11.23SMLNFVEE1456 pKa = 5.39RR1457 pKa = 11.84NKK1459 pKa = 10.98AWLTVVSAVTSAIGILLLVTKK1480 pKa = 10.21IFKK1483 pKa = 10.52KK1484 pKa = 10.7EE1485 pKa = 3.65EE1486 pKa = 4.31SKK1488 pKa = 11.26DD1489 pKa = 3.36EE1490 pKa = 3.97RR1491 pKa = 11.84AYY1493 pKa = 11.45NPTLPVAKK1501 pKa = 9.81PKK1503 pKa = 9.87GTFPVSQRR1511 pKa = 11.84EE1512 pKa = 4.36FKK1514 pKa = 11.22NEE1516 pKa = 3.52APYY1519 pKa = 10.73DD1520 pKa = 3.79GQLEE1524 pKa = 4.54HH1525 pKa = 7.34IISQMAYY1532 pKa = 7.56ITGSTTGHH1540 pKa = 5.99ITHH1543 pKa = 7.16CAGYY1547 pKa = 9.19QHH1549 pKa = 7.36DD1550 pKa = 4.69EE1551 pKa = 4.6IILHH1555 pKa = 5.29GHH1557 pKa = 5.39SIKK1560 pKa = 10.85YY1561 pKa = 10.14LEE1563 pKa = 4.24QEE1565 pKa = 4.25EE1566 pKa = 4.75EE1567 pKa = 4.11LTLHH1571 pKa = 6.19YY1572 pKa = 9.96KK1573 pKa = 10.74NKK1575 pKa = 9.63VFPIEE1580 pKa = 4.19QPSVTQVTLGGKK1592 pKa = 9.46PMDD1595 pKa = 4.1LAIVKK1600 pKa = 9.99CKK1602 pKa = 10.71LPFRR1606 pKa = 11.84FKK1608 pKa = 10.92KK1609 pKa = 9.64NSKK1612 pKa = 10.37YY1613 pKa = 8.4YY1614 pKa = 7.95TNKK1617 pKa = 10.01IGTEE1621 pKa = 3.93SMLIWMTEE1629 pKa = 3.44QGIITKK1635 pKa = 9.47EE1636 pKa = 4.07VQRR1639 pKa = 11.84VHH1641 pKa = 6.5HH1642 pKa = 6.55SGGIKK1647 pKa = 8.83TRR1649 pKa = 11.84EE1650 pKa = 4.17GTEE1653 pKa = 3.83STKK1656 pKa = 10.53TISYY1660 pKa = 7.54TVKK1663 pKa = 10.09SCKK1666 pKa = 10.15GMCGGLLISKK1676 pKa = 10.17VEE1678 pKa = 4.17GNFKK1682 pKa = 10.38ILGMHH1687 pKa = 6.63IAGNGEE1693 pKa = 3.97MGVAIPFNFLKK1704 pKa = 10.85NDD1706 pKa = 3.28MSDD1709 pKa = 3.06QGIVTEE1715 pKa = 4.2VTPIQPMYY1723 pKa = 10.67INTKK1727 pKa = 7.79SQIHH1731 pKa = 6.37KK1732 pKa = 9.61SPVYY1736 pKa = 10.05GAVEE1740 pKa = 4.4VKK1742 pKa = 9.79MGPAVLSKK1750 pKa = 10.8SDD1752 pKa = 3.37TRR1754 pKa = 11.84LEE1756 pKa = 4.16EE1757 pKa = 4.34PVDD1760 pKa = 3.89CLVKK1764 pKa = 10.58KK1765 pKa = 10.31SASKK1769 pKa = 10.27YY1770 pKa = 9.52RR1771 pKa = 11.84VNKK1774 pKa = 9.43FQVNNEE1780 pKa = 3.27LWQGVKK1786 pKa = 10.43ACVKK1790 pKa = 10.38SKK1792 pKa = 9.88FRR1794 pKa = 11.84EE1795 pKa = 3.9IFGVNGIVDD1804 pKa = 4.36MKK1806 pKa = 10.18TAILGTSHH1814 pKa = 6.4VNSMDD1819 pKa = 3.41LSTSAGYY1826 pKa = 10.81SFVKK1830 pKa = 10.17SGYY1833 pKa = 9.0KK1834 pKa = 10.14KK1835 pKa = 10.28KK1836 pKa = 10.67DD1837 pKa = 3.95LICLEE1842 pKa = 4.44PFSVSPMLEE1851 pKa = 3.69KK1852 pKa = 10.49LVQEE1856 pKa = 4.64KK1857 pKa = 9.15FHH1859 pKa = 6.72NLLKK1863 pKa = 10.72GNQITTIFNTCLKK1876 pKa = 10.92DD1877 pKa = 3.65EE1878 pKa = 4.38LRR1880 pKa = 11.84KK1881 pKa = 9.78LDD1883 pKa = 4.58KK1884 pKa = 10.69IATGKK1889 pKa = 7.31TRR1891 pKa = 11.84CIEE1894 pKa = 3.93ACEE1897 pKa = 3.54IDD1899 pKa = 3.7YY1900 pKa = 11.02CIVYY1904 pKa = 9.99RR1905 pKa = 11.84MIMMEE1910 pKa = 4.57IYY1912 pKa = 10.55DD1913 pKa = 5.04KK1914 pKa = 10.61IYY1916 pKa = 8.81QTPCYY1921 pKa = 10.02YY1922 pKa = 10.63SGLAVGINPYY1932 pKa = 10.2RR1933 pKa = 11.84DD1934 pKa = 2.66WHH1936 pKa = 6.28FMINALNDD1944 pKa = 3.2YY1945 pKa = 9.38NYY1947 pKa = 10.75EE1948 pKa = 3.93MDD1950 pKa = 3.36YY1951 pKa = 11.03SQYY1954 pKa = 11.17DD1955 pKa = 3.59GSLSSMLLWEE1965 pKa = 4.59AVQVLAYY1972 pKa = 10.51CHH1974 pKa = 6.98DD1975 pKa = 4.14SPDD1978 pKa = 4.91LVMQLHH1984 pKa = 6.31KK1985 pKa = 10.58PVIDD1989 pKa = 3.67SDD1991 pKa = 3.66HH1992 pKa = 6.72VVFNEE1997 pKa = 3.18RR1998 pKa = 11.84WLIHH2002 pKa = 6.16GGMPSGSPCTTVLNSLCNLMMCIYY2026 pKa = 6.85TTNLISPGIDD2036 pKa = 3.25CLPIVYY2042 pKa = 10.12GDD2044 pKa = 4.26DD2045 pKa = 4.19VILSLDD2051 pKa = 3.64KK2052 pKa = 10.86EE2053 pKa = 4.34IEE2055 pKa = 4.06PEE2057 pKa = 3.79RR2058 pKa = 11.84LQSIMAEE2065 pKa = 4.11SFGAEE2070 pKa = 3.91VTGSRR2075 pKa = 11.84KK2076 pKa = 10.06DD2077 pKa = 3.48EE2078 pKa = 4.44PPSLKK2083 pKa = 10.06PRR2085 pKa = 11.84MEE2087 pKa = 3.92VEE2089 pKa = 3.72FLKK2092 pKa = 10.66RR2093 pKa = 11.84KK2094 pKa = 9.15PGYY2097 pKa = 9.63FPEE2100 pKa = 4.27STFIVGKK2107 pKa = 10.48LDD2109 pKa = 3.55TEE2111 pKa = 4.15NMIQHH2116 pKa = 6.55LMWMKK2121 pKa = 10.61NFSTFKK2127 pKa = 10.53QQLQSYY2133 pKa = 9.99LMEE2136 pKa = 5.0LCLHH2140 pKa = 6.56GKK2142 pKa = 8.14DD2143 pKa = 3.81TYY2145 pKa = 9.11QHH2147 pKa = 5.5YY2148 pKa = 11.21VKK2150 pKa = 10.46ILNPYY2155 pKa = 8.43LKK2157 pKa = 9.58EE2158 pKa = 3.8WNIPVDD2164 pKa = 3.94DD2165 pKa = 4.39YY2166 pKa = 11.82EE2167 pKa = 4.43VVIGKK2172 pKa = 8.12LVPMVFDD2179 pKa = 4.07
MM1 pKa = 7.1EE2 pKa = 5.4TIKK5 pKa = 10.88SIADD9 pKa = 3.36MATGVTKK16 pKa = 10.44TIDD19 pKa = 3.16ATINSVNEE27 pKa = 4.17IITNTDD33 pKa = 2.91NASGGDD39 pKa = 3.66ILTKK43 pKa = 10.68VADD46 pKa = 4.17DD47 pKa = 4.05ASNILGPNCYY57 pKa = 9.06ATTSEE62 pKa = 4.71PEE64 pKa = 4.07NKK66 pKa = 10.0DD67 pKa = 3.16VVQATTTVNTTNLTQHH83 pKa = 7.01PSAPTLPFTPDD94 pKa = 3.48FSNVDD99 pKa = 3.79TFHH102 pKa = 8.47SMAYY106 pKa = 8.4DD107 pKa = 3.36TTTGSKK113 pKa = 10.42NPNKK117 pKa = 10.02LVRR120 pKa = 11.84LTTHH124 pKa = 6.24AWASTLQRR132 pKa = 11.84GHH134 pKa = 6.42QIDD137 pKa = 4.44HH138 pKa = 6.49VNLPVDD144 pKa = 4.41FWDD147 pKa = 4.0EE148 pKa = 3.97QRR150 pKa = 11.84KK151 pKa = 7.67PAYY154 pKa = 9.98GHH156 pKa = 6.7AKK158 pKa = 8.59YY159 pKa = 9.62FAAVRR164 pKa = 11.84CGFHH168 pKa = 6.55FQVQVNVNQGTAGSALVVYY187 pKa = 9.09EE188 pKa = 4.27PKK190 pKa = 10.56PVVDD194 pKa = 3.6YY195 pKa = 11.55DD196 pKa = 3.46KK197 pKa = 11.27DD198 pKa = 3.93LEE200 pKa = 4.62FGAFTNLPHH209 pKa = 8.42VLMNLAEE216 pKa = 4.24TTQADD221 pKa = 3.67LCIPYY226 pKa = 10.25VADD229 pKa = 3.45TNYY232 pKa = 10.33VKK234 pKa = 10.06TDD236 pKa = 3.29SSDD239 pKa = 3.22LGQLKK244 pKa = 10.45VYY246 pKa = 10.0VWTPLSIPSGSSNQVDD262 pKa = 3.92VTILGSLLQLDD273 pKa = 4.55FQNPRR278 pKa = 11.84VYY280 pKa = 10.45GQNVDD285 pKa = 3.61IYY287 pKa = 9.88DD288 pKa = 3.95TAPSKK293 pKa = 10.28PIPLRR298 pKa = 11.84KK299 pKa = 7.99TKK301 pKa = 10.49YY302 pKa = 8.77LTMSTKK308 pKa = 10.68YY309 pKa = 9.45KK310 pKa = 7.12WTRR313 pKa = 11.84NKK315 pKa = 9.99VDD317 pKa = 3.08IAEE320 pKa = 4.99GPGSMNMANVLSTTAAQSVALVGEE344 pKa = 4.2RR345 pKa = 11.84AFYY348 pKa = 10.58DD349 pKa = 3.49PRR351 pKa = 11.84TAGSKK356 pKa = 10.44SRR358 pKa = 11.84FDD360 pKa = 4.03DD361 pKa = 3.85LVKK364 pKa = 10.36ISQLFSVMADD374 pKa = 3.02STTPSANHH382 pKa = 7.06GIDD385 pKa = 3.05QKK387 pKa = 11.8GYY389 pKa = 9.7FKK391 pKa = 10.54WSANSDD397 pKa = 3.36PQAIVHH403 pKa = 6.41RR404 pKa = 11.84NLVHH408 pKa = 7.46LNLFPNLKK416 pKa = 10.02VFEE419 pKa = 4.24NSYY422 pKa = 10.94SYY424 pKa = 11.1FRR426 pKa = 11.84GSLIIRR432 pKa = 11.84LSVYY436 pKa = 10.53ASTFNRR442 pKa = 11.84GRR444 pKa = 11.84LNGFFPNSSTDD455 pKa = 3.28EE456 pKa = 3.94TSEE459 pKa = 3.82IDD461 pKa = 3.29NAIYY465 pKa = 8.45TICDD469 pKa = 3.05IGSDD473 pKa = 3.4NSFEE477 pKa = 3.83ITIPYY482 pKa = 9.85SFSTWMRR489 pKa = 11.84KK490 pKa = 6.8THH492 pKa = 6.15GKK494 pKa = 9.53PIGLFQIEE502 pKa = 4.38VLNRR506 pKa = 11.84LTYY509 pKa = 10.5NYY511 pKa = 10.37SSPNEE516 pKa = 4.16VYY518 pKa = 10.8CIVQGKK524 pKa = 8.26MGQDD528 pKa = 2.78AKK530 pKa = 10.45FFCPTGSLVTFQNSWGSQMDD550 pKa = 3.95LTDD553 pKa = 4.21PLCIEE558 pKa = 5.51DD559 pKa = 4.21SVEE562 pKa = 4.05DD563 pKa = 3.95CKK565 pKa = 10.67QTITPTEE572 pKa = 4.24LGLTSAQDD580 pKa = 3.98DD581 pKa = 4.6GPLGNDD587 pKa = 3.01KK588 pKa = 10.88PNYY591 pKa = 9.05FLNFKK596 pKa = 10.56SMNVDD601 pKa = 2.91IFTVSHH607 pKa = 5.95TKK609 pKa = 10.03VDD611 pKa = 4.22NIFGRR616 pKa = 11.84AWFAHH621 pKa = 4.71VHH623 pKa = 6.61DD624 pKa = 4.72FTNDD628 pKa = 3.45GLWRR632 pKa = 11.84QGLEE636 pKa = 4.16FPKK639 pKa = 9.94EE640 pKa = 3.83GHH642 pKa = 6.33GALSLLFAYY651 pKa = 7.5FTGEE655 pKa = 4.02LNIHH659 pKa = 5.6VLFLSDD665 pKa = 3.84RR666 pKa = 11.84GFLRR670 pKa = 11.84VGHH673 pKa = 6.39TYY675 pKa = 9.16DD676 pKa = 3.53TEE678 pKa = 4.42TNRR681 pKa = 11.84TNFLSSSGIITVPAGEE697 pKa = 4.17QMTLSVPSYY706 pKa = 10.4SNKK709 pKa = 9.43PLRR712 pKa = 11.84TVRR715 pKa = 11.84SSNALGYY722 pKa = 9.46LLCKK726 pKa = 9.93PLLTGTSSGRR736 pKa = 11.84IEE738 pKa = 4.06IFLSLRR744 pKa = 11.84CPNFFFPLPAPKK756 pKa = 9.73PATRR760 pKa = 11.84KK761 pKa = 9.58YY762 pKa = 10.61RR763 pKa = 11.84GDD765 pKa = 3.39LATWSDD771 pKa = 3.44QSPYY775 pKa = 10.3GRR777 pKa = 11.84QGKK780 pKa = 8.28KK781 pKa = 8.46QLMKK785 pKa = 10.57LAYY788 pKa = 9.8LDD790 pKa = 3.3RR791 pKa = 11.84GFYY794 pKa = 9.13KK795 pKa = 10.31HH796 pKa = 6.03YY797 pKa = 10.32GIVVGDD803 pKa = 4.5DD804 pKa = 3.69VYY806 pKa = 11.6QLDD809 pKa = 3.92SDD811 pKa = 5.8DD812 pKa = 3.91IFKK815 pKa = 9.46TALTGKK821 pKa = 10.39AKK823 pKa = 8.95FTKK826 pKa = 9.74TRR828 pKa = 11.84LTPDD832 pKa = 2.7WVVEE836 pKa = 4.22EE837 pKa = 4.43EE838 pKa = 4.71CEE840 pKa = 4.22LDD842 pKa = 3.58YY843 pKa = 11.32FRR845 pKa = 11.84IKK847 pKa = 10.79YY848 pKa = 10.24LEE850 pKa = 4.06SSVNSEE856 pKa = 4.98HH857 pKa = 7.22IFSVDD862 pKa = 3.45NNCEE866 pKa = 4.07TIAKK870 pKa = 9.82DD871 pKa = 3.03IFGSHH876 pKa = 6.48SLSQHH881 pKa = 4.42QQIGLIGTILLTAGLMSTIKK901 pKa = 10.08TPVNPTTIKK910 pKa = 10.69EE911 pKa = 4.36FFNHH915 pKa = 7.16AIEE918 pKa = 4.73GDD920 pKa = 3.86EE921 pKa = 4.14QGLSLLVQKK930 pKa = 9.44CTTFFSSAATEE941 pKa = 4.31LLDD944 pKa = 3.76NDD946 pKa = 4.08LVKK949 pKa = 10.64FIIKK953 pKa = 9.57ILVRR957 pKa = 11.84ILCYY961 pKa = 9.58MVLYY965 pKa = 9.5CHH967 pKa = 7.01KK968 pKa = 10.47PNILTTACLSTLLVMDD984 pKa = 4.13VTSSSVLSPSCKK996 pKa = 10.58ALMQCLMDD1004 pKa = 4.76GDD1006 pKa = 4.18VKK1008 pKa = 10.98KK1009 pKa = 10.53LAEE1012 pKa = 4.22VVAEE1016 pKa = 4.31SMSNTDD1022 pKa = 3.39DD1023 pKa = 5.99DD1024 pKa = 4.85EE1025 pKa = 5.71IKK1027 pKa = 10.74EE1028 pKa = 4.19QICDD1032 pKa = 3.4TVKK1035 pKa = 9.38YY1036 pKa = 8.64TKK1038 pKa = 10.32QILSNQGPFKK1048 pKa = 10.75GFNEE1052 pKa = 3.59ISTAFRR1058 pKa = 11.84HH1059 pKa = 5.54IDD1061 pKa = 2.73WWIQTLLKK1069 pKa = 10.26IKK1071 pKa = 10.87DD1072 pKa = 3.5MVLSVFKK1079 pKa = 10.7PSVEE1083 pKa = 3.71KK1084 pKa = 10.68RR1085 pKa = 11.84AVEE1088 pKa = 3.54WLEE1091 pKa = 3.63RR1092 pKa = 11.84NKK1094 pKa = 10.75EE1095 pKa = 4.27HH1096 pKa = 6.47VCSILDD1102 pKa = 3.61YY1103 pKa = 11.19ASDD1106 pKa = 4.22IIVKK1110 pKa = 10.6SKK1112 pKa = 11.0DD1113 pKa = 3.15QTKK1116 pKa = 9.83MKK1118 pKa = 9.17TQEE1121 pKa = 3.58FYY1123 pKa = 11.02QRR1125 pKa = 11.84YY1126 pKa = 8.9NDD1128 pKa = 4.04CLSKK1132 pKa = 10.5FKK1134 pKa = 10.46PIMAMCFRR1142 pKa = 11.84SCHH1145 pKa = 5.26NSISNTVYY1153 pKa = 11.05RR1154 pKa = 11.84LFQEE1158 pKa = 4.75LARR1161 pKa = 11.84IPNRR1165 pKa = 11.84MATQNDD1171 pKa = 5.23LIRR1174 pKa = 11.84VEE1176 pKa = 5.3PIGIWIQGEE1185 pKa = 4.03PGQGKK1190 pKa = 9.58SFLTHH1195 pKa = 6.13TLSKK1199 pKa = 10.43QLQKK1203 pKa = 9.82TCGLQGIYY1211 pKa = 10.15TNPTASEE1218 pKa = 4.03FMDD1221 pKa = 5.61GYY1223 pKa = 11.17DD1224 pKa = 3.42NQDD1227 pKa = 2.26IHH1229 pKa = 8.84LIDD1232 pKa = 5.54DD1233 pKa = 4.85LGQTRR1238 pKa = 11.84KK1239 pKa = 9.95EE1240 pKa = 3.53RR1241 pKa = 11.84DD1242 pKa = 2.84IEE1244 pKa = 4.21MLCNCISSDD1253 pKa = 3.67PDD1255 pKa = 3.49IVPMAHH1261 pKa = 6.85LEE1263 pKa = 4.28EE1264 pKa = 4.96KK1265 pKa = 10.95GKK1267 pKa = 10.65FYY1269 pKa = 10.64TSKK1272 pKa = 10.95LVIATTNKK1280 pKa = 9.44PDD1282 pKa = 3.66FSSTVLLDD1290 pKa = 3.19SGALRR1295 pKa = 11.84RR1296 pKa = 11.84RR1297 pKa = 11.84FPYY1300 pKa = 10.1IMHH1303 pKa = 6.27IRR1305 pKa = 11.84AAKK1308 pKa = 9.87HH1309 pKa = 4.44YY1310 pKa = 9.81SKK1312 pKa = 10.67SGKK1315 pKa = 10.35LNVSQAMPHH1324 pKa = 6.01MSTGEE1329 pKa = 3.84CWEE1332 pKa = 3.98VSKK1335 pKa = 11.23NGRR1338 pKa = 11.84DD1339 pKa = 3.31WEE1341 pKa = 4.31TLKK1344 pKa = 11.15LKK1346 pKa = 10.5EE1347 pKa = 5.18LIDD1350 pKa = 5.18KK1351 pKa = 9.17ITVDD1355 pKa = 3.66YY1356 pKa = 10.61KK1357 pKa = 11.26EE1358 pKa = 5.47RR1359 pKa = 11.84IANYY1363 pKa = 7.57NTWKK1367 pKa = 10.41KK1368 pKa = 9.9QLEE1371 pKa = 4.35DD1372 pKa = 3.46QTLDD1376 pKa = 3.87DD1377 pKa = 5.34LDD1379 pKa = 4.95DD1380 pKa = 3.97AVSYY1384 pKa = 10.61IKK1386 pKa = 10.54HH1387 pKa = 6.43NYY1389 pKa = 8.4PDD1391 pKa = 5.49AIPYY1395 pKa = 9.26IDD1397 pKa = 4.35EE1398 pKa = 4.15YY1399 pKa = 11.82LNIEE1403 pKa = 4.2MSTLIEE1409 pKa = 3.92QMEE1412 pKa = 4.28AFIEE1416 pKa = 4.24PKK1418 pKa = 10.23PSVFKK1423 pKa = 11.02CFASRR1428 pKa = 11.84VGDD1431 pKa = 3.9KK1432 pKa = 10.43IKK1434 pKa = 10.09EE1435 pKa = 3.89ASRR1438 pKa = 11.84EE1439 pKa = 4.13VVKK1442 pKa = 10.58WFSDD1446 pKa = 3.24KK1447 pKa = 10.87LKK1449 pKa = 11.23SMLNFVEE1456 pKa = 5.39RR1457 pKa = 11.84NKK1459 pKa = 10.98AWLTVVSAVTSAIGILLLVTKK1480 pKa = 10.21IFKK1483 pKa = 10.52KK1484 pKa = 10.7EE1485 pKa = 3.65EE1486 pKa = 4.31SKK1488 pKa = 11.26DD1489 pKa = 3.36EE1490 pKa = 3.97RR1491 pKa = 11.84AYY1493 pKa = 11.45NPTLPVAKK1501 pKa = 9.81PKK1503 pKa = 9.87GTFPVSQRR1511 pKa = 11.84EE1512 pKa = 4.36FKK1514 pKa = 11.22NEE1516 pKa = 3.52APYY1519 pKa = 10.73DD1520 pKa = 3.79GQLEE1524 pKa = 4.54HH1525 pKa = 7.34IISQMAYY1532 pKa = 7.56ITGSTTGHH1540 pKa = 5.99ITHH1543 pKa = 7.16CAGYY1547 pKa = 9.19QHH1549 pKa = 7.36DD1550 pKa = 4.69EE1551 pKa = 4.6IILHH1555 pKa = 5.29GHH1557 pKa = 5.39SIKK1560 pKa = 10.85YY1561 pKa = 10.14LEE1563 pKa = 4.24QEE1565 pKa = 4.25EE1566 pKa = 4.75EE1567 pKa = 4.11LTLHH1571 pKa = 6.19YY1572 pKa = 9.96KK1573 pKa = 10.74NKK1575 pKa = 9.63VFPIEE1580 pKa = 4.19QPSVTQVTLGGKK1592 pKa = 9.46PMDD1595 pKa = 4.1LAIVKK1600 pKa = 9.99CKK1602 pKa = 10.71LPFRR1606 pKa = 11.84FKK1608 pKa = 10.92KK1609 pKa = 9.64NSKK1612 pKa = 10.37YY1613 pKa = 8.4YY1614 pKa = 7.95TNKK1617 pKa = 10.01IGTEE1621 pKa = 3.93SMLIWMTEE1629 pKa = 3.44QGIITKK1635 pKa = 9.47EE1636 pKa = 4.07VQRR1639 pKa = 11.84VHH1641 pKa = 6.5HH1642 pKa = 6.55SGGIKK1647 pKa = 8.83TRR1649 pKa = 11.84EE1650 pKa = 4.17GTEE1653 pKa = 3.83STKK1656 pKa = 10.53TISYY1660 pKa = 7.54TVKK1663 pKa = 10.09SCKK1666 pKa = 10.15GMCGGLLISKK1676 pKa = 10.17VEE1678 pKa = 4.17GNFKK1682 pKa = 10.38ILGMHH1687 pKa = 6.63IAGNGEE1693 pKa = 3.97MGVAIPFNFLKK1704 pKa = 10.85NDD1706 pKa = 3.28MSDD1709 pKa = 3.06QGIVTEE1715 pKa = 4.2VTPIQPMYY1723 pKa = 10.67INTKK1727 pKa = 7.79SQIHH1731 pKa = 6.37KK1732 pKa = 9.61SPVYY1736 pKa = 10.05GAVEE1740 pKa = 4.4VKK1742 pKa = 9.79MGPAVLSKK1750 pKa = 10.8SDD1752 pKa = 3.37TRR1754 pKa = 11.84LEE1756 pKa = 4.16EE1757 pKa = 4.34PVDD1760 pKa = 3.89CLVKK1764 pKa = 10.58KK1765 pKa = 10.31SASKK1769 pKa = 10.27YY1770 pKa = 9.52RR1771 pKa = 11.84VNKK1774 pKa = 9.43FQVNNEE1780 pKa = 3.27LWQGVKK1786 pKa = 10.43ACVKK1790 pKa = 10.38SKK1792 pKa = 9.88FRR1794 pKa = 11.84EE1795 pKa = 3.9IFGVNGIVDD1804 pKa = 4.36MKK1806 pKa = 10.18TAILGTSHH1814 pKa = 6.4VNSMDD1819 pKa = 3.41LSTSAGYY1826 pKa = 10.81SFVKK1830 pKa = 10.17SGYY1833 pKa = 9.0KK1834 pKa = 10.14KK1835 pKa = 10.28KK1836 pKa = 10.67DD1837 pKa = 3.95LICLEE1842 pKa = 4.44PFSVSPMLEE1851 pKa = 3.69KK1852 pKa = 10.49LVQEE1856 pKa = 4.64KK1857 pKa = 9.15FHH1859 pKa = 6.72NLLKK1863 pKa = 10.72GNQITTIFNTCLKK1876 pKa = 10.92DD1877 pKa = 3.65EE1878 pKa = 4.38LRR1880 pKa = 11.84KK1881 pKa = 9.78LDD1883 pKa = 4.58KK1884 pKa = 10.69IATGKK1889 pKa = 7.31TRR1891 pKa = 11.84CIEE1894 pKa = 3.93ACEE1897 pKa = 3.54IDD1899 pKa = 3.7YY1900 pKa = 11.02CIVYY1904 pKa = 9.99RR1905 pKa = 11.84MIMMEE1910 pKa = 4.57IYY1912 pKa = 10.55DD1913 pKa = 5.04KK1914 pKa = 10.61IYY1916 pKa = 8.81QTPCYY1921 pKa = 10.02YY1922 pKa = 10.63SGLAVGINPYY1932 pKa = 10.2RR1933 pKa = 11.84DD1934 pKa = 2.66WHH1936 pKa = 6.28FMINALNDD1944 pKa = 3.2YY1945 pKa = 9.38NYY1947 pKa = 10.75EE1948 pKa = 3.93MDD1950 pKa = 3.36YY1951 pKa = 11.03SQYY1954 pKa = 11.17DD1955 pKa = 3.59GSLSSMLLWEE1965 pKa = 4.59AVQVLAYY1972 pKa = 10.51CHH1974 pKa = 6.98DD1975 pKa = 4.14SPDD1978 pKa = 4.91LVMQLHH1984 pKa = 6.31KK1985 pKa = 10.58PVIDD1989 pKa = 3.67SDD1991 pKa = 3.66HH1992 pKa = 6.72VVFNEE1997 pKa = 3.18RR1998 pKa = 11.84WLIHH2002 pKa = 6.16GGMPSGSPCTTVLNSLCNLMMCIYY2026 pKa = 6.85TTNLISPGIDD2036 pKa = 3.25CLPIVYY2042 pKa = 10.12GDD2044 pKa = 4.26DD2045 pKa = 4.19VILSLDD2051 pKa = 3.64KK2052 pKa = 10.86EE2053 pKa = 4.34IEE2055 pKa = 4.06PEE2057 pKa = 3.79RR2058 pKa = 11.84LQSIMAEE2065 pKa = 4.11SFGAEE2070 pKa = 3.91VTGSRR2075 pKa = 11.84KK2076 pKa = 10.06DD2077 pKa = 3.48EE2078 pKa = 4.44PPSLKK2083 pKa = 10.06PRR2085 pKa = 11.84MEE2087 pKa = 3.92VEE2089 pKa = 3.72FLKK2092 pKa = 10.66RR2093 pKa = 11.84KK2094 pKa = 9.15PGYY2097 pKa = 9.63FPEE2100 pKa = 4.27STFIVGKK2107 pKa = 10.48LDD2109 pKa = 3.55TEE2111 pKa = 4.15NMIQHH2116 pKa = 6.55LMWMKK2121 pKa = 10.61NFSTFKK2127 pKa = 10.53QQLQSYY2133 pKa = 9.99LMEE2136 pKa = 5.0LCLHH2140 pKa = 6.56GKK2142 pKa = 8.14DD2143 pKa = 3.81TYY2145 pKa = 9.11QHH2147 pKa = 5.5YY2148 pKa = 11.21VKK2150 pKa = 10.46ILNPYY2155 pKa = 8.43LKK2157 pKa = 9.58EE2158 pKa = 3.8WNIPVDD2164 pKa = 3.94DD2165 pKa = 4.39YY2166 pKa = 11.82EE2167 pKa = 4.43VVIGKK2172 pKa = 8.12LVPMVFDD2179 pKa = 4.07
Molecular weight: 245.87 kDa
Isoelectric point according different methods:
Peptides (in silico digests for buttom-up proteomics)
Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.| Try ESI |
 |
|---|
| ChTry ESI |
|
|---|
| ArgC ESI |
|
|---|
| LysN ESI |
|
|---|
| TryLysC ESI |
|
|---|
| Try MALDI |
|
|---|
| ChTry MALDI |
|
|---|
| ArgC MALDI |
|
|---|
| LysN MALDI |
|
|---|
| TryLysC MALDI |
|
|---|
| Try LTQ |
|
|---|
| ChTry LTQ |
|
|---|
| ArgC LTQ |
|
|---|
| LysN LTQ |
|
|---|
| TryLysC LTQ |
|
|---|
| Try MSlow |
|
|---|
| ChTry MSlow |
|
|---|
| ArgC MSlow |
|
|---|
| LysN MSlow |
|
|---|
| TryLysC MSlow |
|
|---|
| Try MShigh |
|
|---|
| ChTry MShigh |
|
|---|
| ArgC MShigh |
|
|---|
| LysN MShigh |
|
|---|
| TryLysC MShigh |
|
|---|
General Statistics
Number of major isoforms |
Number of additional isoforms |
Number of all proteins |
Number of amino acids |
Min. Seq. Length |
Max. Seq. Length |
Avg. Seq. Length |
Avg. Mol. Weight |
|---|---|---|---|---|---|---|---|
0 |
2179 |
2179 |
2179 |
2179.0 |
245.87 |
Amino acid frequency
Ala |
Cys |
Asp |
Glu |
Phe |
Gly |
His |
Ile |
Lys |
Leu |
|---|---|---|---|---|---|---|---|---|---|
4.727 ± 0.0 | 2.111 ± 0.0 |
6.104 ± 0.0 | 5.324 ± 0.0 |
4.406 ± 0.0 | 5.691 ± 0.0 |
2.524 ± 0.0 | 6.7 ± 0.0 |
7.297 ± 0.0 | 8.674 ± 0.0 |
Met |
Asn |
Gln |
Pro |
Arg |
Ser |
Thr |
Val |
Trp |
Tyr |
|---|---|---|---|---|---|---|---|---|---|
2.937 ± 0.0 | 5.002 ± 0.0 |
4.543 ± 0.0 | 3.809 ± 0.0 |
3.212 ± 0.0 | 7.756 ± 0.0 |
7.343 ± 0.0 | 6.563 ± 0.0 |
1.239 ± 0.0 | 4.039 ± 0.0 |
Most of the basic statistics you can see at this page can be downloaded from this CSV file
See this proteome in:
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here
| Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 | Contact: Lukasz P. Kozlowski |