Amino acid dipepetide frequency for Changjiang picorna-like virus 11

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.215AlaAla: 5.215 ± 0.595
1.203AlaCys: 1.203 ± 0.037
5.616AlaAsp: 5.616 ± 1.041
2.407AlaGlu: 2.407 ± 0.074
3.209AlaPhe: 3.209 ± 1.618
5.215AlaGly: 5.215 ± 1.246
0.401AlaHis: 0.401 ± 0.205
4.813AlaIle: 4.813 ± 0.8
4.813AlaLys: 4.813 ± 0.149
6.017AlaLeu: 6.017 ± 3.068
1.604AlaMet: 1.604 ± 0.167
1.604AlaAsn: 1.604 ± 1.134
4.813AlaPro: 4.813 ± 2.101
3.61AlaGln: 3.61 ± 0.762
2.407AlaArg: 2.407 ± 0.576
4.813AlaSer: 4.813 ± 0.149
4.813AlaThr: 4.813 ± 2.101
6.418AlaVal: 6.418 ± 1.283
1.604AlaTrp: 1.604 ± 0.818
2.808AlaTyr: 2.808 ± 1.171
0.0AlaXaa: 0.0 ± 0.0
Cys
1.203CysAla: 1.203 ± 0.037
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.401CysGlu: 0.401 ± 0.205
0.0CysPhe: 0.0 ± 0.0
0.802CysGly: 0.802 ± 0.242
0.0CysHis: 0.0 ± 0.0
0.401CysIle: 0.401 ± 0.446
0.401CysLys: 0.401 ± 0.205
0.802CysLeu: 0.802 ± 0.242
0.0CysMet: 0.0 ± 0.0
0.401CysAsn: 0.401 ± 0.446
0.802CysPro: 0.802 ± 0.893
0.401CysGln: 0.401 ± 0.205
0.802CysArg: 0.802 ± 0.409
1.203CysSer: 1.203 ± 0.688
1.604CysThr: 1.604 ± 0.818
1.203CysVal: 1.203 ± 0.037
0.401CysTrp: 0.401 ± 0.205
0.802CysTyr: 0.802 ± 0.893
0.0CysXaa: 0.0 ± 0.0
Asp
2.006AspAla: 2.006 ± 0.279
0.802AspCys: 0.802 ± 0.409
2.407AspAsp: 2.407 ± 0.725
4.011AspGlu: 4.011 ± 0.744
4.813AspPhe: 4.813 ± 0.8
2.808AspGly: 2.808 ± 0.13
0.802AspHis: 0.802 ± 0.409
3.61AspIle: 3.61 ± 0.539
2.407AspLys: 2.407 ± 0.074
5.215AspLeu: 5.215 ± 0.056
0.802AspMet: 0.802 ± 0.893
3.209AspAsn: 3.209 ± 0.335
0.802AspPro: 0.802 ± 0.409
1.203AspGln: 1.203 ± 0.614
0.802AspArg: 0.802 ± 0.409
6.819AspSer: 6.819 ± 0.223
5.215AspThr: 5.215 ± 0.056
4.011AspVal: 4.011 ± 0.093
0.802AspTrp: 0.802 ± 0.242
2.808AspTyr: 2.808 ± 0.781
0.0AspXaa: 0.0 ± 0.0
Glu
4.813GluAla: 4.813 ± 0.8
0.802GluCys: 0.802 ± 0.893
2.808GluAsp: 2.808 ± 0.13
4.011GluGlu: 4.011 ± 2.045
2.407GluPhe: 2.407 ± 0.074
2.407GluGly: 2.407 ± 1.227
2.407GluHis: 2.407 ± 1.227
3.209GluIle: 3.209 ± 0.985
4.011GluLys: 4.011 ± 0.744
3.61GluLeu: 3.61 ± 0.539
2.808GluMet: 2.808 ± 0.13
4.011GluAsn: 4.011 ± 0.093
3.209GluPro: 3.209 ± 0.335
1.203GluGln: 1.203 ± 0.614
2.808GluArg: 2.808 ± 0.13
5.616GluSer: 5.616 ± 0.26
1.203GluThr: 1.203 ± 0.037
2.006GluVal: 2.006 ± 0.372
0.401GluTrp: 0.401 ± 0.205
3.209GluTyr: 3.209 ± 0.985
0.0GluXaa: 0.0 ± 0.0
Phe
4.011PheAla: 4.011 ± 1.209
0.401PheCys: 0.401 ± 0.446
2.006PheAsp: 2.006 ± 1.023
5.616PheGlu: 5.616 ± 0.391
2.006PhePhe: 2.006 ± 0.279
3.209PheGly: 3.209 ± 0.316
0.401PheHis: 0.401 ± 0.446
2.006PheIle: 2.006 ± 0.279
2.808PheLys: 2.808 ± 0.781
4.011PheLeu: 4.011 ± 1.395
0.802PheMet: 0.802 ± 0.409
1.203PheAsn: 1.203 ± 0.037
2.407PhePro: 2.407 ± 0.725
2.407PheGln: 2.407 ± 0.074
2.407PheArg: 2.407 ± 0.725
3.61PheSer: 3.61 ± 0.539
4.011PheThr: 4.011 ± 1.395
2.407PheVal: 2.407 ± 2.027
0.401PheTrp: 0.401 ± 0.205
1.604PheTyr: 1.604 ± 0.483
0.0PheXaa: 0.0 ± 0.0
Gly
5.215GlyAla: 5.215 ± 2.548
0.401GlyCys: 0.401 ± 0.205
3.61GlyAsp: 3.61 ± 1.19
2.808GlyGlu: 2.808 ± 0.13
3.61GlyPhe: 3.61 ± 1.413
4.011GlyGly: 4.011 ± 0.744
1.604GlyHis: 1.604 ± 0.167
6.017GlyIle: 6.017 ± 2.417
5.616GlyLys: 5.616 ± 0.26
6.418GlyLeu: 6.418 ± 0.669
1.604GlyMet: 1.604 ± 0.818
1.203GlyAsn: 1.203 ± 0.688
2.407GlyPro: 2.407 ± 0.074
1.604GlyGln: 1.604 ± 0.167
2.006GlyArg: 2.006 ± 0.372
6.017GlySer: 6.017 ± 0.837
4.011GlyThr: 4.011 ± 0.093
6.017GlyVal: 6.017 ± 1.488
0.401GlyTrp: 0.401 ± 0.446
2.006GlyTyr: 2.006 ± 1.023
0.0GlyXaa: 0.0 ± 0.0
His
2.006HisAla: 2.006 ± 1.023
0.0HisCys: 0.0 ± 0.0
0.802HisAsp: 0.802 ± 0.409
0.401HisGlu: 0.401 ± 0.205
2.407HisPhe: 2.407 ± 1.227
2.407HisGly: 2.407 ± 0.725
0.0HisHis: 0.0 ± 0.0
0.401HisIle: 0.401 ± 0.205
0.401HisLys: 0.401 ± 0.205
2.006HisLeu: 2.006 ± 1.023
0.0HisMet: 0.0 ± 0.0
0.401HisAsn: 0.401 ± 0.446
0.401HisPro: 0.401 ± 0.205
0.0HisGln: 0.0 ± 0.0
0.802HisArg: 0.802 ± 0.409
1.203HisSer: 1.203 ± 0.614
0.802HisThr: 0.802 ± 0.242
2.407HisVal: 2.407 ± 0.576
0.401HisTrp: 0.401 ± 0.205
1.203HisTyr: 1.203 ± 0.037
0.0HisXaa: 0.0 ± 0.0
Ile
3.209IleAla: 3.209 ± 0.985
0.0IleCys: 0.0 ± 0.0
4.412IleAsp: 4.412 ± 0.353
2.808IleGlu: 2.808 ± 1.432
3.209IlePhe: 3.209 ± 0.985
2.407IleGly: 2.407 ± 0.074
1.604IleHis: 1.604 ± 0.818
2.006IleIle: 2.006 ± 1.023
6.017IleLys: 6.017 ± 1.116
4.813IleLeu: 4.813 ± 1.153
1.203IleMet: 1.203 ± 0.301
2.808IleAsn: 2.808 ± 0.13
3.209IlePro: 3.209 ± 0.967
0.802IleGln: 0.802 ± 0.409
3.61IleArg: 3.61 ± 0.112
2.407IleSer: 2.407 ± 0.725
4.412IleThr: 4.412 ± 0.353
3.61IleVal: 3.61 ± 0.539
1.203IleTrp: 1.203 ± 1.339
1.203IleTyr: 1.203 ± 1.339
0.0IleXaa: 0.0 ± 0.0
Lys
4.011LysAla: 4.011 ± 1.395
0.0LysCys: 0.0 ± 0.0
4.412LysAsp: 4.412 ± 1.599
5.215LysGlu: 5.215 ± 2.008
2.808LysPhe: 2.808 ± 1.171
3.61LysGly: 3.61 ± 1.19
0.802LysHis: 0.802 ± 0.409
2.006LysIle: 2.006 ± 0.279
6.017LysLys: 6.017 ± 3.068
3.61LysLeu: 3.61 ± 0.112
2.808LysMet: 2.808 ± 0.641
1.203LysAsn: 1.203 ± 0.614
4.011LysPro: 4.011 ± 0.558
2.808LysGln: 2.808 ± 0.13
3.61LysArg: 3.61 ± 1.841
4.011LysSer: 4.011 ± 0.744
4.011LysThr: 4.011 ± 0.093
5.616LysVal: 5.616 ± 0.391
0.0LysTrp: 0.0 ± 0.0
1.203LysTyr: 1.203 ± 0.614
0.0LysXaa: 0.0 ± 0.0
Leu
6.418LeuAla: 6.418 ± 0.019
1.604LeuCys: 1.604 ± 0.818
5.215LeuAsp: 5.215 ± 0.707
4.813LeuGlu: 4.813 ± 0.502
2.006LeuPhe: 2.006 ± 0.279
6.017LeuGly: 6.017 ± 1.488
2.006LeuHis: 2.006 ± 1.023
4.011LeuIle: 4.011 ± 0.744
7.22LeuLys: 7.22 ± 3.031
4.813LeuLeu: 4.813 ± 0.8
0.802LeuMet: 0.802 ± 0.409
6.819LeuAsn: 6.819 ± 0.874
3.61LeuPro: 3.61 ± 2.064
2.808LeuGln: 2.808 ± 0.781
6.418LeuArg: 6.418 ± 0.669
5.616LeuSer: 5.616 ± 1.041
5.616LeuThr: 5.616 ± 2.213
2.006LeuVal: 2.006 ± 0.372
2.407LeuTrp: 2.407 ± 0.576
2.808LeuTyr: 2.808 ± 0.521
0.0LeuXaa: 0.0 ± 0.0
Met
2.407MetAla: 2.407 ± 0.576
0.0MetCys: 0.0 ± 0.0
0.401MetAsp: 0.401 ± 0.205
1.203MetGlu: 1.203 ± 0.037
1.203MetPhe: 1.203 ± 0.614
0.401MetGly: 0.401 ± 0.205
0.401MetHis: 0.401 ± 0.205
1.604MetIle: 1.604 ± 0.167
3.209MetLys: 3.209 ± 0.316
1.203MetLeu: 1.203 ± 0.614
0.802MetMet: 0.802 ± 0.409
1.203MetAsn: 1.203 ± 0.614
1.203MetPro: 1.203 ± 0.037
0.401MetGln: 0.401 ± 0.205
1.203MetArg: 1.203 ± 0.037
3.61MetSer: 3.61 ± 0.112
2.407MetThr: 2.407 ± 0.074
2.006MetVal: 2.006 ± 0.372
0.401MetTrp: 0.401 ± 0.446
0.802MetTyr: 0.802 ± 0.409
0.0MetXaa: 0.0 ± 0.0
Asn
4.011AsnAla: 4.011 ± 1.209
0.401AsnCys: 0.401 ± 0.205
1.203AsnAsp: 1.203 ± 0.037
2.808AsnGlu: 2.808 ± 0.13
3.209AsnPhe: 3.209 ± 0.316
3.61AsnGly: 3.61 ± 0.539
0.802AsnHis: 0.802 ± 0.409
3.209AsnIle: 3.209 ± 0.335
1.203AsnLys: 1.203 ± 0.614
3.61AsnLeu: 3.61 ± 0.539
2.006AsnMet: 2.006 ± 0.372
2.006AsnAsn: 2.006 ± 0.93
1.203AsnPro: 1.203 ± 0.037
0.802AsnGln: 0.802 ± 0.409
0.802AsnArg: 0.802 ± 0.242
2.808AsnSer: 2.808 ± 0.521
2.407AsnThr: 2.407 ± 2.027
3.209AsnVal: 3.209 ± 0.967
0.401AsnTrp: 0.401 ± 0.446
3.209AsnTyr: 3.209 ± 0.985
0.0AsnXaa: 0.0 ± 0.0
Pro
2.407ProAla: 2.407 ± 0.074
0.0ProCys: 0.0 ± 0.0
3.209ProAsp: 3.209 ± 0.967
2.808ProGlu: 2.808 ± 0.13
2.006ProPhe: 2.006 ± 0.93
2.808ProGly: 2.808 ± 0.521
0.401ProHis: 0.401 ± 0.205
3.209ProIle: 3.209 ± 1.618
0.802ProLys: 0.802 ± 0.409
4.011ProLeu: 4.011 ± 1.209
1.604ProMet: 1.604 ± 0.818
0.802ProAsn: 0.802 ± 0.242
0.802ProPro: 0.802 ± 0.242
2.407ProGln: 2.407 ± 1.227
1.604ProArg: 1.604 ± 0.483
2.006ProSer: 2.006 ± 0.279
6.017ProThr: 6.017 ± 2.138
4.813ProVal: 4.813 ± 2.101
0.401ProTrp: 0.401 ± 0.446
2.006ProTyr: 2.006 ± 0.93
0.0ProXaa: 0.0 ± 0.0
Gln
2.808GlnAla: 2.808 ± 0.13
0.0GlnCys: 0.0 ± 0.0
2.006GlnAsp: 2.006 ± 0.372
0.401GlnGlu: 0.401 ± 0.205
0.802GlnPhe: 0.802 ± 0.409
2.006GlnGly: 2.006 ± 1.023
0.401GlnHis: 0.401 ± 0.205
1.604GlnIle: 1.604 ± 0.167
1.203GlnLys: 1.203 ± 0.614
4.011GlnLeu: 4.011 ± 1.209
0.401GlnMet: 0.401 ± 0.205
1.604GlnAsn: 1.604 ± 0.818
1.604GlnPro: 1.604 ± 0.483
0.0GlnGln: 0.0 ± 0.0
1.604GlnArg: 1.604 ± 0.818
2.808GlnSer: 2.808 ± 0.781
2.407GlnThr: 2.407 ± 1.227
2.006GlnVal: 2.006 ± 1.581
0.802GlnTrp: 0.802 ± 0.242
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.407ArgAla: 2.407 ± 0.725
0.401ArgCys: 0.401 ± 0.205
3.209ArgAsp: 3.209 ± 0.335
2.407ArgGlu: 2.407 ± 0.576
4.011ArgPhe: 4.011 ± 0.744
4.011ArgGly: 4.011 ± 0.558
0.802ArgHis: 0.802 ± 0.242
4.011ArgIle: 4.011 ± 0.744
2.407ArgLys: 2.407 ± 1.227
5.215ArgLeu: 5.215 ± 0.707
0.802ArgMet: 0.802 ± 0.409
1.604ArgAsn: 1.604 ± 0.818
2.006ArgPro: 2.006 ± 0.93
0.802ArgGln: 0.802 ± 0.409
3.209ArgArg: 3.209 ± 0.335
4.412ArgSer: 4.412 ± 0.353
0.401ArgThr: 0.401 ± 0.446
4.813ArgVal: 4.813 ± 1.804
0.401ArgTrp: 0.401 ± 0.205
1.203ArgTyr: 1.203 ± 0.614
0.0ArgXaa: 0.0 ± 0.0
Ser
8.424SerAla: 8.424 ± 4.165
0.401SerCys: 0.401 ± 0.446
3.61SerAsp: 3.61 ± 0.762
3.61SerGlu: 3.61 ± 1.19
4.011SerPhe: 4.011 ± 0.744
4.412SerGly: 4.412 ± 0.948
0.802SerHis: 0.802 ± 0.409
4.412SerIle: 4.412 ± 0.353
6.017SerLys: 6.017 ± 2.138
7.621SerLeu: 7.621 ± 2.585
2.407SerMet: 2.407 ± 0.074
4.412SerAsn: 4.412 ± 1.004
2.808SerPro: 2.808 ± 0.521
2.407SerGln: 2.407 ± 1.376
5.215SerArg: 5.215 ± 0.707
6.418SerSer: 6.418 ± 0.632
6.017SerThr: 6.017 ± 0.837
4.813SerVal: 4.813 ± 0.149
2.006SerTrp: 2.006 ± 0.372
3.61SerTyr: 3.61 ± 2.064
0.0SerXaa: 0.0 ± 0.0
Thr
3.61ThrAla: 3.61 ± 0.762
1.604ThrCys: 1.604 ± 0.483
2.808ThrAsp: 2.808 ± 0.521
2.006ThrGlu: 2.006 ± 0.279
2.808ThrPhe: 2.808 ± 0.13
5.616ThrGly: 5.616 ± 0.26
1.203ThrHis: 1.203 ± 0.614
4.412ThrIle: 4.412 ± 1.004
2.006ThrLys: 2.006 ± 0.372
4.813ThrLeu: 4.813 ± 0.502
1.203ThrMet: 1.203 ± 0.037
4.011ThrAsn: 4.011 ± 0.093
2.407ThrPro: 2.407 ± 1.376
2.407ThrGln: 2.407 ± 0.074
4.011ThrArg: 4.011 ± 0.744
7.22ThrSer: 7.22 ± 0.223
4.412ThrThr: 4.412 ± 1.004
6.017ThrVal: 6.017 ± 2.138
0.401ThrTrp: 0.401 ± 0.446
4.813ThrTyr: 4.813 ± 0.502
0.0ThrXaa: 0.0 ± 0.0
Val
5.616ValAla: 5.616 ± 1.692
2.407ValCys: 2.407 ± 1.376
4.813ValAsp: 4.813 ± 1.153
4.412ValGlu: 4.412 ± 1.004
2.006ValPhe: 2.006 ± 0.279
6.418ValGly: 6.418 ± 1.283
1.604ValHis: 1.604 ± 0.167
3.61ValIle: 3.61 ± 0.539
2.407ValLys: 2.407 ± 0.576
7.22ValLeu: 7.22 ± 0.223
3.209ValMet: 3.209 ± 1.636
1.604ValAsn: 1.604 ± 1.134
4.011ValPro: 4.011 ± 0.744
1.604ValGln: 1.604 ± 0.167
1.203ValArg: 1.203 ± 0.614
9.627ValSer: 9.627 ± 4.853
4.011ValThr: 4.011 ± 0.558
4.813ValVal: 4.813 ± 0.8
0.401ValTrp: 0.401 ± 0.205
3.209ValTyr: 3.209 ± 0.967
0.0ValXaa: 0.0 ± 0.0
Trp
1.203TrpAla: 1.203 ± 0.614
0.401TrpCys: 0.401 ± 0.205
1.203TrpAsp: 1.203 ± 0.037
1.203TrpGlu: 1.203 ± 0.614
0.401TrpPhe: 0.401 ± 0.205
0.802TrpGly: 0.802 ± 0.409
0.401TrpHis: 0.401 ± 0.446
0.0TrpIle: 0.0 ± 0.0
0.401TrpLys: 0.401 ± 0.205
1.604TrpLeu: 1.604 ± 1.134
0.0TrpMet: 0.0 ± 0.0
1.203TrpAsn: 1.203 ± 0.037
0.401TrpPro: 0.401 ± 0.205
0.0TrpGln: 0.0 ± 0.0
0.401TrpArg: 0.401 ± 0.205
1.203TrpSer: 1.203 ± 0.037
0.401TrpThr: 0.401 ± 0.446
2.407TrpVal: 2.407 ± 0.725
0.0TrpTrp: 0.0 ± 0.0
0.802TrpTyr: 0.802 ± 0.242
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.407TyrAla: 2.407 ± 0.074
0.802TyrCys: 0.802 ± 0.242
1.604TyrAsp: 1.604 ± 0.483
3.61TyrGlu: 3.61 ± 0.112
0.802TyrPhe: 0.802 ± 0.409
3.61TyrGly: 3.61 ± 0.539
1.604TyrHis: 1.604 ± 0.483
0.802TyrIle: 0.802 ± 0.242
2.407TyrLys: 2.407 ± 0.074
2.407TyrLeu: 2.407 ± 1.376
0.802TyrMet: 0.802 ± 0.242
1.604TyrAsn: 1.604 ± 0.483
2.006TyrPro: 2.006 ± 0.279
0.802TyrGln: 0.802 ± 0.409
3.61TyrArg: 3.61 ± 0.762
2.006TyrSer: 2.006 ± 0.279
3.61TyrThr: 3.61 ± 0.762
3.61TyrVal: 3.61 ± 1.19
1.203TyrTrp: 1.203 ± 0.614
0.802TyrTyr: 0.802 ± 0.242
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2494 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski