Plasmodium falciparum (isolate NF54)

Taxonomy: cellular organisms; Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium falciparum

Average proteome isoelectric point is 7.23

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 5920 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|W7K8M3|W7K8M3_PLAFO Uncharacterized protein OS=Plasmodium falciparum (isolate NF54) OX=5843 GN=PFNF54_05119 PE=4 SV=1
MM1 pKa = 7.87CDD3 pKa = 4.34DD4 pKa = 4.07TNQMYY9 pKa = 11.12DD10 pKa = 3.81DD11 pKa = 3.81TNKK14 pKa = 10.54RR15 pKa = 11.84YY16 pKa = 10.57DD17 pKa = 4.35DD18 pKa = 3.85TNKK21 pKa = 9.98MYY23 pKa = 11.1DD24 pKa = 4.36DD25 pKa = 4.04TNKK28 pKa = 9.32MCDD31 pKa = 4.31DD32 pKa = 4.02TNKK35 pKa = 9.39MCDD38 pKa = 4.32DD39 pKa = 3.91TNKK42 pKa = 10.04MYY44 pKa = 11.12DD45 pKa = 4.36DD46 pKa = 4.04TNKK49 pKa = 9.32MCDD52 pKa = 4.32DD53 pKa = 3.91TNKK56 pKa = 10.04MYY58 pKa = 11.12DD59 pKa = 4.36DD60 pKa = 4.04TNKK63 pKa = 9.32MCDD66 pKa = 4.32DD67 pKa = 3.91TNKK70 pKa = 10.04MYY72 pKa = 11.13DD73 pKa = 4.37DD74 pKa = 3.96TNKK77 pKa = 10.0MYY79 pKa = 11.1DD80 pKa = 4.36DD81 pKa = 4.04TNKK84 pKa = 9.34MCDD87 pKa = 3.39DD88 pKa = 3.78SS89 pKa = 4.3

Molecular weight: 10.71 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|W7JVG4|W7JVG4_PLAFO Small nuclear ribonucleoprotein Sm D3 OS=Plasmodium falciparum (isolate NF54) OX=5843 GN=CK202_3892 PE=3 SV=1
MM1 pKa = 7.47KK2 pKa = 10.52KK3 pKa = 8.97MRR5 pKa = 11.84KK6 pKa = 9.76KK7 pKa = 6.88MTKK10 pKa = 8.52MKK12 pKa = 10.34NIKK15 pKa = 10.1RR16 pKa = 11.84KK17 pKa = 6.52TKK19 pKa = 8.75RR20 pKa = 11.84KK21 pKa = 9.38KK22 pKa = 10.38RR23 pKa = 11.84MVMMMNLMMNMMKK36 pKa = 10.45KK37 pKa = 9.13MKK39 pKa = 9.97KK40 pKa = 9.47KK41 pKa = 10.07KK42 pKa = 9.26KK43 pKa = 9.17KK44 pKa = 9.47KK45 pKa = 8.15RR46 pKa = 11.84KK47 pKa = 9.41KK48 pKa = 9.82RR49 pKa = 11.84IKK51 pKa = 10.25KK52 pKa = 10.16KK53 pKa = 9.58IIKK56 pKa = 9.91KK57 pKa = 8.11ITIKK61 pKa = 10.37ILNLMKK67 pKa = 10.33IIIKK71 pKa = 9.75MIMTMNIMKK80 pKa = 10.34KK81 pKa = 10.08IINKK85 pKa = 9.46NIKK88 pKa = 9.85KK89 pKa = 8.57KK90 pKa = 8.54TIKK93 pKa = 10.5NIRR96 pKa = 11.84KK97 pKa = 9.51NNMKK101 pKa = 9.91SIKK104 pKa = 9.92IITIIKK110 pKa = 9.77KK111 pKa = 9.53II112 pKa = 3.56

Molecular weight: 13.86 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

5887

33

5920

3863743

10

10287

652.7

77.03

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

1.955 ± 0.021

1.786 ± 0.015

6.35 ± 0.026

6.959 ± 0.038

4.426 ± 0.027

2.802 ± 0.028

2.425 ± 0.013

9.35 ± 0.037

11.704 ± 0.04

7.649 ± 0.036

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.222 ± 0.014

14.479 ± 0.092

1.956 ± 0.016

2.751 ± 0.015

2.642 ± 0.017

6.421 ± 0.027

4.091 ± 0.021

3.759 ± 0.021

0.495 ± 0.008

5.778 ± 0.029
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski