Amino acid dipepetide frequency for Desulfovibrio piger ATCC 29098

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.737AlaAla: 14.737 ± 0.236	2.241AlaCys: 2.241 ± 0.058	5.689AlaAsp: 5.689 ± 0.093	6.208AlaGlu: 6.208 ± 0.11	3.863AlaPhe: 3.863 ± 0.082	9.716AlaGly: 9.716 ± 0.135	2.133AlaHis: 2.133 ± 0.054	4.327AlaIle: 4.327 ± 0.08	3.112AlaLys: 3.112 ± 0.078	13.156AlaLeu: 13.156 ± 0.168	3.181AlaMet: 3.181 ± 0.058	2.094AlaAsn: 2.094 ± 0.05	5.556AlaPro: 5.556 ± 0.13	3.818AlaGln: 3.818 ± 0.071	8.679AlaArg: 8.679 ± 0.133	5.453AlaSer: 5.453 ± 0.079	4.591AlaThr: 4.591 ± 0.077	8.062AlaVal: 8.062 ± 0.12	1.409AlaTrp: 1.409 ± 0.047	2.284AlaTyr: 2.284 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	1.74CysAla: 1.74 ± 0.049	0.424CysCys: 0.424 ± 0.025	0.766CysAsp: 0.766 ± 0.03	0.723CysGlu: 0.723 ± 0.031	0.632CysPhe: 0.632 ± 0.027	1.787CysGly: 1.787 ± 0.048	0.522CysHis: 0.522 ± 0.03	0.856CysIle: 0.856 ± 0.035	0.499CysLys: 0.499 ± 0.025	1.967CysLeu: 1.967 ± 0.057	0.485CysMet: 0.485 ± 0.025	0.41CysAsn: 0.41 ± 0.021	1.243CysPro: 1.243 ± 0.052	0.429CysGln: 0.429 ± 0.022	1.563CysArg: 1.563 ± 0.048	0.879CysSer: 0.879 ± 0.035	0.764CysThr: 0.764 ± 0.03	1.109CysVal: 1.109 ± 0.04	0.25CysTrp: 0.25 ± 0.018	0.403CysTyr: 0.403 ± 0.024	0.0CysXaa: 0.0 ± 0.0
Asp	6.278AspAla: 6.278 ± 0.097	0.77AspCys: 0.77 ± 0.03	2.86AspAsp: 2.86 ± 0.062	3.33AspGlu: 3.33 ± 0.072	2.247AspPhe: 2.247 ± 0.055	4.827AspGly: 4.827 ± 0.083	0.97AspHis: 0.97 ± 0.032	3.096AspIle: 3.096 ± 0.061	2.074AspLys: 2.074 ± 0.057	5.22AspLeu: 5.22 ± 0.091	1.894AspMet: 1.894 ± 0.05	1.344AspAsn: 1.344 ± 0.038	2.635AspPro: 2.635 ± 0.054	1.258AspGln: 1.258 ± 0.036	3.142AspArg: 3.142 ± 0.074	2.654AspSer: 2.654 ± 0.064	2.471AspThr: 2.471 ± 0.055	3.986AspVal: 3.986 ± 0.07	0.829AspTrp: 0.829 ± 0.034	1.38AspTyr: 1.38 ± 0.037	0.0AspXaa: 0.0 ± 0.0
Glu	7.152GluAla: 7.152 ± 0.105	0.636GluCys: 0.636 ± 0.027	3.412GluAsp: 3.412 ± 0.075	4.318GluGlu: 4.318 ± 0.098	1.626GluPhe: 1.626 ± 0.039	4.682GluGly: 4.682 ± 0.074	1.352GluHis: 1.352 ± 0.038	2.746GluIle: 2.746 ± 0.06	3.238GluLys: 3.238 ± 0.077	6.074GluLeu: 6.074 ± 0.111	1.595GluMet: 1.595 ± 0.043	1.935GluAsn: 1.935 ± 0.059	2.292GluPro: 2.292 ± 0.062	2.62GluGln: 2.62 ± 0.069	4.393GluArg: 4.393 ± 0.089	2.8GluSer: 2.8 ± 0.061	2.637GluThr: 2.637 ± 0.066	3.778GluVal: 3.778 ± 0.079	0.589GluTrp: 0.589 ± 0.025	1.34GluTyr: 1.34 ± 0.04	0.0GluXaa: 0.0 ± 0.0
Phe	3.548PheAla: 3.548 ± 0.078	0.839PheCys: 0.839 ± 0.031	2.017PheAsp: 2.017 ± 0.05	1.775PheGlu: 1.775 ± 0.047	2.017PhePhe: 2.017 ± 0.052	3.064PheGly: 3.064 ± 0.061	0.856PheHis: 0.856 ± 0.034	1.711PheIle: 1.711 ± 0.054	1.043PheLys: 1.043 ± 0.037	4.096PheLeu: 4.096 ± 0.095	1.067PheMet: 1.067 ± 0.04	1.009PheAsn: 1.009 ± 0.037	1.923PhePro: 1.923 ± 0.055	1.022PheGln: 1.022 ± 0.035	2.406PheArg: 2.406 ± 0.06	2.673PheSer: 2.673 ± 0.068	1.937PheThr: 1.937 ± 0.052	2.593PheVal: 2.593 ± 0.051	0.72PheTrp: 0.72 ± 0.031	1.074PheTyr: 1.074 ± 0.04	0.0PheXaa: 0.0 ± 0.0
Gly	7.357GlyAla: 7.357 ± 0.105	1.51GlyCys: 1.51 ± 0.048	3.943GlyAsp: 3.943 ± 0.072	4.51GlyGlu: 4.51 ± 0.078	3.015GlyPhe: 3.015 ± 0.063	6.605GlyGly: 6.605 ± 0.108	1.991GlyHis: 1.991 ± 0.057	4.7GlyIle: 4.7 ± 0.084	4.017GlyLys: 4.017 ± 0.081	9.256GlyLeu: 9.256 ± 0.139	2.909GlyMet: 2.909 ± 0.061	2.204GlyAsn: 2.204 ± 0.05	3.412GlyPro: 3.412 ± 0.061	3.468GlyGln: 3.468 ± 0.061	6.116GlyArg: 6.116 ± 0.105	4.537GlySer: 4.537 ± 0.075	4.439GlyThr: 4.439 ± 0.089	5.534GlyVal: 5.534 ± 0.089	1.225GlyTrp: 1.225 ± 0.04	2.163GlyTyr: 2.163 ± 0.056	0.0GlyXaa: 0.0 ± 0.0
His	2.327HisAla: 2.327 ± 0.06	0.478HisCys: 0.478 ± 0.026	1.247HisAsp: 1.247 ± 0.048	1.242HisGlu: 1.242 ± 0.045	0.835HisPhe: 0.835 ± 0.035	1.942HisGly: 1.942 ± 0.048	0.598HisHis: 0.598 ± 0.031	1.137HisIle: 1.137 ± 0.038	0.839HisLys: 0.839 ± 0.037	2.434HisLeu: 2.434 ± 0.057	0.641HisMet: 0.641 ± 0.031	0.582HisAsn: 0.582 ± 0.025	1.389HisPro: 1.389 ± 0.046	0.649HisGln: 0.649 ± 0.028	1.27HisArg: 1.27 ± 0.041	1.078HisSer: 1.078 ± 0.04	1.07HisThr: 1.07 ± 0.033	1.562HisVal: 1.562 ± 0.05	0.362HisTrp: 0.362 ± 0.021	0.604HisTyr: 0.604 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	4.144IleAla: 4.144 ± 0.086	0.894IleCys: 0.894 ± 0.032	2.138IleAsp: 2.138 ± 0.055	2.138IleGlu: 2.138 ± 0.06	2.193IlePhe: 2.193 ± 0.059	3.179IleGly: 3.179 ± 0.07	0.938IleHis: 0.938 ± 0.033	2.54IleIle: 2.54 ± 0.077	1.689IleLys: 1.689 ± 0.064	4.911IleLeu: 4.911 ± 0.092	1.49IleMet: 1.49 ± 0.05	1.48IleAsn: 1.48 ± 0.042	2.618IlePro: 2.618 ± 0.058	1.247IleGln: 1.247 ± 0.038	3.175IleArg: 3.175 ± 0.065	3.018IleSer: 3.018 ± 0.055	2.484IleThr: 2.484 ± 0.062	3.276IleVal: 3.276 ± 0.072	0.608IleTrp: 0.608 ± 0.028	1.245IleTyr: 1.245 ± 0.039	0.0IleXaa: 0.0 ± 0.0
Lys	4.366LysAla: 4.366 ± 0.093	0.357LysCys: 0.357 ± 0.022	2.206LysAsp: 2.206 ± 0.061	2.63LysGlu: 2.63 ± 0.072	0.963LysPhe: 0.963 ± 0.038	3.034LysGly: 3.034 ± 0.068	0.677LysHis: 0.677 ± 0.025	1.747LysIle: 1.747 ± 0.054	2.41LysLys: 2.41 ± 0.073	3.306LysLeu: 3.306 ± 0.067	1.135LysMet: 1.135 ± 0.037	1.408LysAsn: 1.408 ± 0.05	1.687LysPro: 1.687 ± 0.054	1.247LysGln: 1.247 ± 0.039	2.272LysArg: 2.272 ± 0.056	1.804LysSer: 1.804 ± 0.05	2.0LysThr: 2.0 ± 0.057	2.447LysVal: 2.447 ± 0.059	0.298LysTrp: 0.298 ± 0.019	0.954LysTyr: 0.954 ± 0.044	0.0LysXaa: 0.0 ± 0.0
Leu	13.237LeuAla: 13.237 ± 0.17	2.154LeuCys: 2.154 ± 0.057	6.215LeuAsp: 6.215 ± 0.103	6.73LeuGlu: 6.73 ± 0.12	4.084LeuPhe: 4.084 ± 0.081	8.589LeuGly: 8.589 ± 0.127	2.626LeuHis: 2.626 ± 0.056	3.563LeuIle: 3.563 ± 0.078	3.436LeuLys: 3.436 ± 0.081	13.261LeuLeu: 13.261 ± 0.233	2.62LeuMet: 2.62 ± 0.055	2.431LeuAsn: 2.431 ± 0.06	7.445LeuPro: 7.445 ± 0.128	3.708LeuGln: 3.708 ± 0.073	8.328LeuArg: 8.328 ± 0.13	6.629LeuSer: 6.629 ± 0.097	5.141LeuThr: 5.141 ± 0.086	7.086LeuVal: 7.086 ± 0.113	1.472LeuTrp: 1.472 ± 0.048	2.497LeuTyr: 2.497 ± 0.061	0.0LeuXaa: 0.0 ± 0.0
Met	3.346MetAla: 3.346 ± 0.069	0.288MetCys: 0.288 ± 0.019	1.712MetAsp: 1.712 ± 0.045	1.83MetGlu: 1.83 ± 0.05	0.814MetPhe: 0.814 ± 0.036	2.378MetGly: 2.378 ± 0.052	0.6MetHis: 0.6 ± 0.028	1.043MetIle: 1.043 ± 0.036	1.141MetLys: 1.141 ± 0.035	3.146MetLeu: 3.146 ± 0.065	0.696MetMet: 0.696 ± 0.033	0.738MetAsn: 0.738 ± 0.029	1.861MetPro: 1.861 ± 0.048	1.203MetGln: 1.203 ± 0.04	1.986MetArg: 1.986 ± 0.052	1.753MetSer: 1.753 ± 0.049	1.531MetThr: 1.531 ± 0.042	1.754MetVal: 1.754 ± 0.045	0.208MetTrp: 0.208 ± 0.018	0.487MetTyr: 0.487 ± 0.025	0.0MetXaa: 0.0 ± 0.0
Asn	2.724AsnAla: 2.724 ± 0.063	0.405AsnCys: 0.405 ± 0.02	1.27AsnAsp: 1.27 ± 0.041	1.337AsnGlu: 1.337 ± 0.045	1.1AsnPhe: 1.1 ± 0.032	2.114AsnGly: 2.114 ± 0.052	0.474AsnHis: 0.474 ± 0.024	1.62AsnIle: 1.62 ± 0.051	1.034AsnLys: 1.034 ± 0.037	2.531AsnLeu: 2.531 ± 0.065	0.839AsnMet: 0.839 ± 0.033	0.776AsnAsn: 0.776 ± 0.032	1.508AsnPro: 1.508 ± 0.042	0.649AsnGln: 0.649 ± 0.029	1.515AsnArg: 1.515 ± 0.044	1.364AsnSer: 1.364 ± 0.038	1.254AsnThr: 1.254 ± 0.04	1.893AsnVal: 1.893 ± 0.054	0.368AsnTrp: 0.368 ± 0.022	0.733AsnTyr: 0.733 ± 0.032	0.0AsnXaa: 0.0 ± 0.0
Pro	6.632ProAla: 6.632 ± 0.123	0.973ProCys: 0.973 ± 0.041	3.462ProAsp: 3.462 ± 0.061	4.258ProGlu: 4.258 ± 0.085	2.029ProPhe: 2.029 ± 0.051	4.821ProGly: 4.821 ± 0.077	1.217ProHis: 1.217 ± 0.041	1.519ProIle: 1.519 ± 0.041	1.356ProLys: 1.356 ± 0.04	5.945ProLeu: 5.945 ± 0.098	1.165ProMet: 1.165 ± 0.032	1.003ProAsn: 1.003 ± 0.036	2.399ProPro: 2.399 ± 0.064	2.245ProGln: 2.245 ± 0.057	3.279ProArg: 3.279 ± 0.071	2.789ProSer: 2.789 ± 0.064	1.879ProThr: 1.879 ± 0.046	4.644ProVal: 4.644 ± 0.083	0.832ProTrp: 0.832 ± 0.04	1.249ProTyr: 1.249 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	4.607GlnAla: 4.607 ± 0.084	0.562GlnCys: 0.562 ± 0.031	1.911GlnAsp: 1.911 ± 0.054	2.532GlnGlu: 2.532 ± 0.073	0.942GlnPhe: 0.942 ± 0.039	3.264GlnGly: 3.264 ± 0.074	0.775GlnHis: 0.775 ± 0.032	1.504GlnIle: 1.504 ± 0.041	1.534GlnLys: 1.534 ± 0.042	3.22GlnLeu: 3.22 ± 0.064	0.891GlnMet: 0.891 ± 0.034	0.887GlnAsn: 0.887 ± 0.037	1.736GlnPro: 1.736 ± 0.049	1.686GlnGln: 1.686 ± 0.059	2.751GlnArg: 2.751 ± 0.073	1.649GlnSer: 1.649 ± 0.044	1.616GlnThr: 1.616 ± 0.047	2.197GlnVal: 2.197 ± 0.051	0.562GlnTrp: 0.562 ± 0.026	0.85GlnTyr: 0.85 ± 0.03	0.0GlnXaa: 0.0 ± 0.0
Arg	6.813ArgAla: 6.813 ± 0.126	1.173ArgCys: 1.173 ± 0.043	3.8ArgAsp: 3.8 ± 0.074	4.769ArgGlu: 4.769 ± 0.098	2.61ArgPhe: 2.61 ± 0.052	4.559ArgGly: 4.559 ± 0.084	2.201ArgHis: 2.201 ± 0.059	3.522ArgIle: 3.522 ± 0.071	3.014ArgLys: 3.014 ± 0.06	8.254ArgLeu: 8.254 ± 0.13	2.277ArgMet: 2.277 ± 0.051	1.868ArgAsn: 1.868 ± 0.048	3.944ArgPro: 3.944 ± 0.089	3.678ArgGln: 3.678 ± 0.08	5.841ArgArg: 5.841 ± 0.116	3.389ArgSer: 3.389 ± 0.072	3.155ArgThr: 3.155 ± 0.066	4.201ArgVal: 4.201 ± 0.088	0.972ArgTrp: 0.972 ± 0.035	1.9ArgTyr: 1.9 ± 0.051	0.0ArgXaa: 0.0 ± 0.0
Ser	5.068SerAla: 5.068 ± 0.078	1.035SerCys: 1.035 ± 0.036	2.209SerAsp: 2.209 ± 0.051	2.336SerGlu: 2.336 ± 0.055	2.346SerPhe: 2.346 ± 0.055	5.427SerGly: 5.427 ± 0.081	1.175SerHis: 1.175 ± 0.042	2.641SerIle: 2.641 ± 0.06	1.646SerLys: 1.646 ± 0.048	6.86SerLeu: 6.86 ± 0.113	1.626SerMet: 1.626 ± 0.047	1.235SerAsn: 1.235 ± 0.042	3.131SerPro: 3.131 ± 0.066	1.718SerGln: 1.718 ± 0.044	4.196SerArg: 4.196 ± 0.077	3.213SerSer: 3.213 ± 0.073	2.424SerThr: 2.424 ± 0.056	3.813SerVal: 3.813 ± 0.072	0.787SerTrp: 0.787 ± 0.033	1.299SerTyr: 1.299 ± 0.044	0.0SerXaa: 0.0 ± 0.0
Thr	5.491ThrAla: 5.491 ± 0.109	0.757ThrCys: 0.757 ± 0.032	2.544ThrAsp: 2.544 ± 0.056	2.396ThrGlu: 2.396 ± 0.054	1.838ThrPhe: 1.838 ± 0.055	4.801ThrGly: 4.801 ± 0.08	0.923ThrHis: 0.923 ± 0.035	2.191ThrIle: 2.191 ± 0.057	1.282ThrLys: 1.282 ± 0.045	5.256ThrLeu: 5.256 ± 0.08	1.14ThrMet: 1.14 ± 0.036	1.066ThrAsn: 1.066 ± 0.039	3.174ThrPro: 3.174 ± 0.067	1.205ThrGln: 1.205 ± 0.041	2.872ThrArg: 2.872 ± 0.06	2.592ThrSer: 2.592 ± 0.056	2.276ThrThr: 2.276 ± 0.06	3.803ThrVal: 3.803 ± 0.071	0.499ThrTrp: 0.499 ± 0.028	1.129ThrTyr: 1.129 ± 0.039	0.0ThrXaa: 0.0 ± 0.0
Val	7.084ValAla: 7.084 ± 0.108	1.329ValCys: 1.329 ± 0.039	3.818ValAsp: 3.818 ± 0.068	4.207ValGlu: 4.207 ± 0.085	2.775ValPhe: 2.775 ± 0.062	4.838ValGly: 4.838 ± 0.082	1.344ValHis: 1.344 ± 0.043	3.25ValIle: 3.25 ± 0.059	2.121ValLys: 2.121 ± 0.055	7.966ValLeu: 7.966 ± 0.116	1.901ValMet: 1.901 ± 0.05	1.848ValAsn: 1.848 ± 0.048	3.834ValPro: 3.834 ± 0.07	2.298ValGln: 2.298 ± 0.048	5.288ValArg: 5.288 ± 0.101	3.905ValSer: 3.905 ± 0.067	3.677ValThr: 3.677 ± 0.076	4.906ValVal: 4.906 ± 0.103	0.938ValTrp: 0.938 ± 0.034	1.628ValTyr: 1.628 ± 0.04	0.0ValXaa: 0.0 ± 0.0
Trp	1.119TrpAla: 1.119 ± 0.041	0.213TrpCys: 0.213 ± 0.017	0.622TrpAsp: 0.622 ± 0.03	0.662TrpGlu: 0.662 ± 0.025	0.455TrpPhe: 0.455 ± 0.024	1.045TrpGly: 1.045 ± 0.041	0.381TrpHis: 0.381 ± 0.02	0.555TrpIle: 0.555 ± 0.024	0.573TrpLys: 0.573 ± 0.026	1.906TrpLeu: 1.906 ± 0.064	0.321TrpMet: 0.321 ± 0.022	0.399TrpAsn: 0.399 ± 0.021	0.756TrpPro: 0.756 ± 0.032	0.882TrpGln: 0.882 ± 0.033	1.176TrpArg: 1.176 ± 0.038	0.62TrpSer: 0.62 ± 0.029	0.619TrpThr: 0.619 ± 0.028	0.643TrpVal: 0.643 ± 0.032	0.228TrpTrp: 0.228 ± 0.018	0.366TrpTyr: 0.366 ± 0.023	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.538TyrAla: 2.538 ± 0.056	0.412TyrCys: 0.412 ± 0.024	1.424TyrAsp: 1.424 ± 0.044	1.286TyrGlu: 1.286 ± 0.038	1.007TyrPhe: 1.007 ± 0.037	2.24TyrGly: 2.24 ± 0.056	0.531TyrHis: 0.531 ± 0.025	1.136TyrIle: 1.136 ± 0.041	0.89TyrLys: 0.89 ± 0.038	2.486TyrLeu: 2.486 ± 0.054	0.641TyrMet: 0.641 ± 0.028	0.793TyrAsn: 0.793 ± 0.03	1.152TyrPro: 1.152 ± 0.041	0.65TyrGln: 0.65 ± 0.032	1.69TyrArg: 1.69 ± 0.05	1.387TyrSer: 1.387 ± 0.042	1.274TyrThr: 1.274 ± 0.043	1.667TyrVal: 1.667 ± 0.044	0.383TyrTrp: 0.383 ± 0.019	0.731TyrTyr: 0.731 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3106 proteins (841498 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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