Amino acid dipepetide frequency for Corallococcus sp. H22C18031201

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.079AlaAla: 15.079 ± 0.103	1.332AlaCys: 1.332 ± 0.025	5.341AlaAsp: 5.341 ± 0.05	7.697AlaGlu: 7.697 ± 0.079	4.015AlaPhe: 4.015 ± 0.047	9.895AlaGly: 9.895 ± 0.082	2.639AlaHis: 2.639 ± 0.035	3.22AlaIle: 3.22 ± 0.043	3.171AlaLys: 3.171 ± 0.049	15.692AlaLeu: 15.692 ± 0.128	2.568AlaMet: 2.568 ± 0.033	2.266AlaAsn: 2.266 ± 0.036	7.907AlaPro: 7.907 ± 0.075	4.775AlaGln: 4.775 ± 0.056	11.905AlaArg: 11.905 ± 0.095	7.443AlaSer: 7.443 ± 0.067	6.517AlaThr: 6.517 ± 0.056	9.344AlaVal: 9.344 ± 0.077	1.84AlaTrp: 1.84 ± 0.032	2.403AlaTyr: 2.403 ± 0.029	0.0AlaXaa: 0.0 ± 0.0
Cys	1.209CysAla: 1.209 ± 0.026	0.091CysCys: 0.091 ± 0.006	0.526CysAsp: 0.526 ± 0.018	0.53CysGlu: 0.53 ± 0.014	0.301CysPhe: 0.301 ± 0.012	0.985CysGly: 0.985 ± 0.025	0.257CysHis: 0.257 ± 0.012	0.282CysIle: 0.282 ± 0.01	0.219CysLys: 0.219 ± 0.011	0.893CysLeu: 0.893 ± 0.019	0.143CysMet: 0.143 ± 0.008	0.227CysAsn: 0.227 ± 0.011	0.532CysPro: 0.532 ± 0.019	0.281CysGln: 0.281 ± 0.011	0.644CysArg: 0.644 ± 0.017	0.543CysSer: 0.543 ± 0.02	0.513CysThr: 0.513 ± 0.016	0.757CysVal: 0.757 ± 0.018	0.11CysTrp: 0.11 ± 0.007	0.177CysTyr: 0.177 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	7.715AspAla: 7.715 ± 0.063	0.464AspCys: 0.464 ± 0.014	2.481AspAsp: 2.481 ± 0.035	3.205AspGlu: 3.205 ± 0.032	2.051AspPhe: 2.051 ± 0.031	4.9AspGly: 4.9 ± 0.064	0.847AspHis: 0.847 ± 0.017	1.703AspIle: 1.703 ± 0.029	1.247AspLys: 1.247 ± 0.027	5.304AspLeu: 5.304 ± 0.048	0.858AspMet: 0.858 ± 0.019	0.974AspAsn: 0.974 ± 0.025	2.962AspPro: 2.962 ± 0.041	1.08AspGln: 1.08 ± 0.023	3.051AspArg: 3.051 ± 0.041	2.665AspSer: 2.665 ± 0.036	2.703AspThr: 2.703 ± 0.035	4.792AspVal: 4.792 ± 0.044	0.76AspTrp: 0.76 ± 0.016	1.076AspTyr: 1.076 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	8.579GluAla: 8.579 ± 0.089	0.422GluCys: 0.422 ± 0.016	3.155GluAsp: 3.155 ± 0.036	3.71GluGlu: 3.71 ± 0.052	1.588GluPhe: 1.588 ± 0.028	5.254GluGly: 5.254 ± 0.053	1.468GluHis: 1.468 ± 0.023	1.42GluIle: 1.42 ± 0.026	1.967GluLys: 1.967 ± 0.038	7.067GluLeu: 7.067 ± 0.072	1.131GluMet: 1.131 ± 0.02	1.075GluAsn: 1.075 ± 0.024	3.61GluPro: 3.61 ± 0.043	2.528GluGln: 2.528 ± 0.04	6.215GluArg: 6.215 ± 0.067	3.328GluSer: 3.328 ± 0.038	2.63GluThr: 2.63 ± 0.032	5.333GluVal: 5.333 ± 0.051	0.732GluTrp: 0.732 ± 0.022	1.063GluTyr: 1.063 ± 0.025	0.0GluXaa: 0.0 ± 0.0
Phe	3.685PheAla: 3.685 ± 0.035	0.309PheCys: 0.309 ± 0.01	2.083PheAsp: 2.083 ± 0.026	2.135PheGlu: 2.135 ± 0.031	1.355PhePhe: 1.355 ± 0.026	2.803PheGly: 2.803 ± 0.04	0.806PheHis: 0.806 ± 0.019	1.225PheIle: 1.225 ± 0.023	0.816PheLys: 0.816 ± 0.018	3.402PheLeu: 3.402 ± 0.038	0.592PheMet: 0.592 ± 0.016	0.869PheAsn: 0.869 ± 0.022	1.606PhePro: 1.606 ± 0.025	1.228PheGln: 1.228 ± 0.021	2.312PheArg: 2.312 ± 0.032	2.103PheSer: 2.103 ± 0.028	2.098PheThr: 2.098 ± 0.036	2.637PheVal: 2.637 ± 0.036	0.413PheTrp: 0.413 ± 0.016	0.715PheTyr: 0.715 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	10.287GlyAla: 10.287 ± 0.076	0.959GlyCys: 0.959 ± 0.025	4.186GlyAsp: 4.186 ± 0.043	4.963GlyGlu: 4.963 ± 0.047	3.025GlyPhe: 3.025 ± 0.039	7.607GlyGly: 7.607 ± 0.077	1.897GlyHis: 1.897 ± 0.027	2.828GlyIle: 2.828 ± 0.038	2.728GlyLys: 2.728 ± 0.043	9.236GlyLeu: 9.236 ± 0.084	2.046GlyMet: 2.046 ± 0.029	1.934GlyAsn: 1.934 ± 0.035	4.369GlyPro: 4.369 ± 0.05	2.994GlyGln: 2.994 ± 0.033	6.661GlyArg: 6.661 ± 0.057	4.738GlySer: 4.738 ± 0.055	5.486GlyThr: 5.486 ± 0.066	7.061GlyVal: 7.061 ± 0.068	1.329GlyTrp: 1.329 ± 0.024	1.957GlyTyr: 1.957 ± 0.03	0.0GlyXaa: 0.0 ± 0.0
His	2.765HisAla: 2.765 ± 0.036	0.224HisCys: 0.224 ± 0.008	0.992HisAsp: 0.992 ± 0.021	1.205HisGlu: 1.205 ± 0.024	0.84HisPhe: 0.84 ± 0.018	2.006HisGly: 2.006 ± 0.031	0.613HisHis: 0.613 ± 0.018	0.593HisIle: 0.593 ± 0.016	0.383HisLys: 0.383 ± 0.013	2.434HisLeu: 2.434 ± 0.034	0.324HisMet: 0.324 ± 0.011	0.372HisAsn: 0.372 ± 0.011	1.658HisPro: 1.658 ± 0.027	0.677HisGln: 0.677 ± 0.018	1.71HisArg: 1.71 ± 0.026	1.011HisSer: 1.011 ± 0.02	0.949HisThr: 0.949 ± 0.019	1.829HisVal: 1.829 ± 0.026	0.308HisTrp: 0.308 ± 0.01	0.5HisTyr: 0.5 ± 0.015	0.0HisXaa: 0.0 ± 0.0
Ile	3.603IleAla: 3.603 ± 0.037	0.271IleCys: 0.271 ± 0.01	1.671IleAsp: 1.671 ± 0.03	1.838IleGlu: 1.838 ± 0.025	0.866IlePhe: 0.866 ± 0.021	2.198IleGly: 2.198 ± 0.033	0.778IleHis: 0.778 ± 0.017	1.058IleIle: 1.058 ± 0.026	0.708IleLys: 0.708 ± 0.019	2.592IleLeu: 2.592 ± 0.034	0.327IleMet: 0.327 ± 0.011	0.8IleAsn: 0.8 ± 0.019	1.875IlePro: 1.875 ± 0.03	1.079IleGln: 1.079 ± 0.02	2.007IleArg: 2.007 ± 0.024	1.608IleSer: 1.608 ± 0.027	1.643IleThr: 1.643 ± 0.028	2.15IleVal: 2.15 ± 0.035	0.273IleTrp: 0.273 ± 0.011	0.569IleTyr: 0.569 ± 0.015	0.0IleXaa: 0.0 ± 0.0
Lys	3.441LysAla: 3.441 ± 0.052	0.194LysCys: 0.194 ± 0.009	1.705LysAsp: 1.705 ± 0.035	1.59LysGlu: 1.59 ± 0.031	0.633LysPhe: 0.633 ± 0.015	2.292LysGly: 2.292 ± 0.04	0.504LysHis: 0.504 ± 0.015	0.652LysIle: 0.652 ± 0.017	1.253LysLys: 1.253 ± 0.03	3.007LysLeu: 3.007 ± 0.04	0.566LysMet: 0.566 ± 0.016	0.664LysAsn: 0.664 ± 0.019	1.748LysPro: 1.748 ± 0.031	0.97LysGln: 0.97 ± 0.021	2.02LysArg: 2.02 ± 0.032	1.441LysSer: 1.441 ± 0.026	1.407LysThr: 1.407 ± 0.025	2.458LysVal: 2.458 ± 0.036	0.264LysTrp: 0.264 ± 0.011	0.538LysTyr: 0.538 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	14.414LeuAla: 14.414 ± 0.121	1.033LeuCys: 1.033 ± 0.026	5.995LeuAsp: 5.995 ± 0.054	7.164LeuGlu: 7.164 ± 0.077	3.546LeuPhe: 3.546 ± 0.041	9.88LeuGly: 9.88 ± 0.08	2.297LeuHis: 2.297 ± 0.029	2.766LeuIle: 2.766 ± 0.033	3.31LeuLys: 3.31 ± 0.041	11.795LeuLeu: 11.795 ± 0.107	1.982LeuMet: 1.982 ± 0.03	2.112LeuAsn: 2.112 ± 0.031	6.678LeuPro: 6.678 ± 0.07	3.425LeuGln: 3.425 ± 0.042	9.35LeuArg: 9.35 ± 0.071	7.142LeuSer: 7.142 ± 0.055	6.258LeuThr: 6.258 ± 0.057	8.702LeuVal: 8.702 ± 0.067	1.358LeuTrp: 1.358 ± 0.026	2.172LeuTyr: 2.172 ± 0.035	0.0LeuXaa: 0.0 ± 0.0
Met	2.416MetAla: 2.416 ± 0.033	0.136MetCys: 0.136 ± 0.007	1.011MetAsp: 1.011 ± 0.021	1.174MetGlu: 1.174 ± 0.022	0.489MetPhe: 0.489 ± 0.015	1.767MetGly: 1.767 ± 0.031	0.381MetHis: 0.381 ± 0.013	0.384MetIle: 0.384 ± 0.013	0.784MetLys: 0.784 ± 0.016	1.983MetLeu: 1.983 ± 0.03	0.426MetMet: 0.426 ± 0.014	0.527MetAsn: 0.527 ± 0.014	1.218MetPro: 1.218 ± 0.019	0.579MetGln: 0.579 ± 0.015	1.647MetArg: 1.647 ± 0.025	1.413MetSer: 1.413 ± 0.027	1.141MetThr: 1.141 ± 0.023	1.394MetVal: 1.394 ± 0.022	0.18MetTrp: 0.18 ± 0.008	0.26MetTyr: 0.26 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	2.529AsnAla: 2.529 ± 0.027	0.207AsnCys: 0.207 ± 0.01	1.003AsnAsp: 1.003 ± 0.022	0.969AsnGlu: 0.969 ± 0.024	0.697AsnPhe: 0.697 ± 0.018	1.854AsnGly: 1.854 ± 0.04	0.45AsnHis: 0.45 ± 0.013	0.773AsnIle: 0.773 ± 0.018	0.498AsnLys: 0.498 ± 0.015	2.254AsnLeu: 2.254 ± 0.036	0.345AsnMet: 0.345 ± 0.013	0.532AsnAsn: 0.532 ± 0.021	1.584AsnPro: 1.584 ± 0.024	0.692AsnGln: 0.692 ± 0.019	1.337AsnArg: 1.337 ± 0.023	0.968AsnSer: 0.968 ± 0.023	1.207AsnThr: 1.207 ± 0.026	1.73AsnVal: 1.73 ± 0.028	0.261AsnTrp: 0.261 ± 0.01	0.502AsnTyr: 0.502 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	7.474ProAla: 7.474 ± 0.076	0.384ProCys: 0.384 ± 0.013	3.4ProAsp: 3.4 ± 0.04	4.852ProGlu: 4.852 ± 0.053	1.906ProPhe: 1.906 ± 0.03	5.587ProGly: 5.587 ± 0.056	1.216ProHis: 1.216 ± 0.023	1.468ProIle: 1.468 ± 0.022	1.437ProLys: 1.437 ± 0.027	6.085ProLeu: 6.085 ± 0.061	1.276ProMet: 1.276 ± 0.023	1.175ProAsn: 1.175 ± 0.023	4.776ProPro: 4.776 ± 0.071	1.779ProGln: 1.779 ± 0.027	4.572ProArg: 4.572 ± 0.052	3.992ProSer: 3.992 ± 0.047	3.406ProThr: 3.406 ± 0.041	5.056ProVal: 5.056 ± 0.062	0.869ProTrp: 0.869 ± 0.021	1.065ProTyr: 1.065 ± 0.02	0.0ProXaa: 0.0 ± 0.0
Gln	4.353GlnAla: 4.353 ± 0.053	0.277GlnCys: 0.277 ± 0.012	1.617GlnAsp: 1.617 ± 0.027	1.938GlnGlu: 1.938 ± 0.03	0.867GlnPhe: 0.867 ± 0.019	3.174GlnGly: 3.174 ± 0.041	0.685GlnHis: 0.685 ± 0.015	0.742GlnIle: 0.742 ± 0.019	0.973GlnLys: 0.973 ± 0.025	3.668GlnLeu: 3.668 ± 0.044	0.596GlnMet: 0.596 ± 0.018	0.587GlnAsn: 0.587 ± 0.016	2.045GlnPro: 2.045 ± 0.047	1.314GlnGln: 1.314 ± 0.032	3.049GlnArg: 3.049 ± 0.037	1.73GlnSer: 1.73 ± 0.026	1.494GlnThr: 1.494 ± 0.027	3.308GlnVal: 3.308 ± 0.039	0.464GlnTrp: 0.464 ± 0.014	0.624GlnTyr: 0.624 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	10.493ArgAla: 10.493 ± 0.088	0.729ArgCys: 0.729 ± 0.019	4.01ArgAsp: 4.01 ± 0.044	5.751ArgGlu: 5.751 ± 0.069	3.141ArgPhe: 3.141 ± 0.039	6.008ArgGly: 6.008 ± 0.052	1.814ArgHis: 1.814 ± 0.029	2.84ArgIle: 2.84 ± 0.032	2.151ArgLys: 2.151 ± 0.033	9.298ArgLeu: 9.298 ± 0.083	1.97ArgMet: 1.97 ± 0.027	1.471ArgAsn: 1.471 ± 0.025	4.524ArgPro: 4.524 ± 0.05	2.683ArgGln: 2.683 ± 0.036	6.641ArgArg: 6.641 ± 0.07	3.734ArgSer: 3.734 ± 0.042	4.17ArgThr: 4.17 ± 0.044	6.977ArgVal: 6.977 ± 0.053	1.25ArgTrp: 1.25 ± 0.024	1.895ArgTyr: 1.895 ± 0.026	0.0ArgXaa: 0.0 ± 0.0
Ser	7.044SerAla: 7.044 ± 0.057	0.515SerCys: 0.515 ± 0.015	2.718SerAsp: 2.718 ± 0.033	3.267SerGlu: 3.267 ± 0.036	2.044SerPhe: 2.044 ± 0.03	5.604SerGly: 5.604 ± 0.06	1.141SerHis: 1.141 ± 0.019	1.643SerIle: 1.643 ± 0.023	1.29SerLys: 1.29 ± 0.026	6.618SerLeu: 6.618 ± 0.06	1.125SerMet: 1.125 ± 0.023	1.172SerAsn: 1.172 ± 0.02	3.918SerPro: 3.918 ± 0.049	1.76SerGln: 1.76 ± 0.026	4.485SerArg: 4.485 ± 0.046	3.464SerSer: 3.464 ± 0.045	3.222SerThr: 3.222 ± 0.043	4.493SerVal: 4.493 ± 0.056	0.787SerTrp: 0.787 ± 0.016	1.115SerTyr: 1.115 ± 0.02	0.0SerXaa: 0.0 ± 0.0
Thr	6.131ThrAla: 6.131 ± 0.064	0.565ThrCys: 0.565 ± 0.02	2.501ThrAsp: 2.501 ± 0.038	2.932ThrGlu: 2.932 ± 0.03	2.038ThrPhe: 2.038 ± 0.031	4.976ThrGly: 4.976 ± 0.05	1.228ThrHis: 1.228 ± 0.024	1.169ThrIle: 1.169 ± 0.022	1.096ThrLys: 1.096 ± 0.024	6.554ThrLeu: 6.554 ± 0.056	0.764ThrMet: 0.764 ± 0.017	1.104ThrAsn: 1.104 ± 0.02	4.239ThrPro: 4.239 ± 0.049	2.066ThrGln: 2.066 ± 0.029	4.152ThrArg: 4.152 ± 0.041	3.16ThrSer: 3.16 ± 0.039	2.956ThrThr: 2.956 ± 0.047	4.712ThrVal: 4.712 ± 0.059	0.861ThrTrp: 0.861 ± 0.019	1.286ThrTyr: 1.286 ± 0.026	0.0ThrXaa: 0.0 ± 0.0
Val	10.135ValAla: 10.135 ± 0.089	0.767ValCys: 0.767 ± 0.02	4.698ValAsp: 4.698 ± 0.053	5.459ValGlu: 5.459 ± 0.047	2.498ValPhe: 2.498 ± 0.033	6.615ValGly: 6.615 ± 0.061	1.69ValHis: 1.69 ± 0.025	2.367ValIle: 2.367 ± 0.033	2.413ValLys: 2.413 ± 0.036	9.52ValLeu: 9.52 ± 0.078	1.587ValMet: 1.587 ± 0.028	1.692ValAsn: 1.692 ± 0.028	4.858ValPro: 4.858 ± 0.054	2.421ValGln: 2.421 ± 0.029	6.746ValArg: 6.746 ± 0.051	4.97ValSer: 4.97 ± 0.056	4.779ValThr: 4.779 ± 0.063	7.206ValVal: 7.206 ± 0.076	0.954ValTrp: 0.954 ± 0.022	1.529ValTyr: 1.529 ± 0.028	0.0ValXaa: 0.0 ± 0.0
Trp	1.364TrpAla: 1.364 ± 0.024	0.133TrpCys: 0.133 ± 0.007	0.648TrpAsp: 0.648 ± 0.017	0.731TrpGlu: 0.731 ± 0.023	0.434TrpPhe: 0.434 ± 0.015	1.097TrpGly: 1.097 ± 0.022	0.291TrpHis: 0.291 ± 0.01	0.302TrpIle: 0.302 ± 0.011	0.448TrpLys: 0.448 ± 0.014	1.691TrpLeu: 1.691 ± 0.028	0.371TrpMet: 0.371 ± 0.011	0.371TrpAsn: 0.371 ± 0.012	0.63TrpPro: 0.63 ± 0.016	0.442TrpGln: 0.442 ± 0.013	1.273TrpArg: 1.273 ± 0.028	0.848TrpSer: 0.848 ± 0.019	0.824TrpThr: 0.824 ± 0.018	1.19TrpVal: 1.19 ± 0.022	0.228TrpTrp: 0.228 ± 0.009	0.243TrpTyr: 0.243 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.335TyrAla: 2.335 ± 0.03	0.207TyrCys: 0.207 ± 0.01	1.098TyrAsp: 1.098 ± 0.029	1.164TyrGlu: 1.164 ± 0.024	0.855TyrPhe: 0.855 ± 0.02	1.789TyrGly: 1.789 ± 0.027	0.393TyrHis: 0.393 ± 0.012	0.479TyrIle: 0.479 ± 0.014	0.456TyrLys: 0.456 ± 0.017	2.288TyrLeu: 2.288 ± 0.033	0.311TyrMet: 0.311 ± 0.01	0.468TyrAsn: 0.468 ± 0.016	1.036TyrPro: 1.036 ± 0.02	0.734TyrGln: 0.734 ± 0.018	1.774TyrArg: 1.774 ± 0.029	1.124TyrSer: 1.124 ± 0.023	1.085TyrThr: 1.085 ± 0.025	1.778TyrVal: 1.778 ± 0.028	0.314TyrTrp: 0.314 ± 0.011	0.5TyrTyr: 0.5 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 7103 proteins (2681737 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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